Emg1 (EMG1 N1-specific pseudouridine methyltransferase) - Rat Genome Database

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Gene: Emg1 (EMG1 N1-specific pseudouridine methyltransferase) Mus musculus
Analyze
Symbol: Emg1
Name: EMG1 N1-specific pseudouridine methyltransferase
RGD ID: 1316987
MGI Page MGI
Description: Predicted to enable identical protein binding activity; rRNA (pseudouridine) methyltransferase activity; and rRNA binding activity. Acts upstream of or within blastocyst development and nucleologenesis. Predicted to be located in chromosome; nucleolus; and nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleus. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system; and integumental system. Used to study Bowen-Conradi syndrome. Human ortholog(s) of this gene implicated in Bowen-Conradi syndrome. Orthologous to human EMG1 (EMG1 N1-specific pseudouridine methyltransferase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 18S rRNA (pseudouridine(1248)-N1)-methyltransferase; 18S rRNA (pseudouridine-N1-)-methyltransferase NEP1; 18S rRNA Psi1248 methyltransferase; C2f; EMG1 nucleolar protein homolog; gene rich cluster, C2f; Grcc2; Grcc2f; nucleolar protein EMG1 homolog; probable ribosome biogenesis protein NEP1; ribosomal RNA small subunit methyltransferase NEP1; ribosome biogenesis protein NEP1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,681,344 - 124,689,118 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,681,048 - 124,689,141 (-)EnsemblGRCm39 Ensembl
GRCm386124,704,370 - 124,712,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,704,085 - 124,712,178 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,654,388 - 124,662,196 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,670,006 - 124,677,746 (-)NCBIMGSCv36mm8
Celera6126,386,095 - 126,393,903 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
clobetasol  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
diethyl malate  (ISO)
folic acid  (EXP)
genistein  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP)
menadione  (ISO)
methimazole  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP)
pirinixic acid  (EXP)
potassium chromate  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium dichromate  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (ISO)
nucleolus  (IBA,IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)
small-subunit processome  (IBA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9445485   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:17967808   PMID:18799693   PMID:20858271   PMID:21677750   PMID:21873635   PMID:24194600   PMID:24457600   PMID:25708872   PMID:26336360   PMID:27113764  
PMID:30196744   PMID:38355793  


Genomics

Comparative Map Data
Emg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,681,344 - 124,689,118 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,681,048 - 124,689,141 (-)EnsemblGRCm39 Ensembl
GRCm386124,704,370 - 124,712,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,704,085 - 124,712,178 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,654,388 - 124,662,196 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,670,006 - 124,677,746 (-)NCBIMGSCv36mm8
Celera6126,386,095 - 126,393,903 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
EMG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,970,913 - 6,997,428 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,970,913 - 6,979,936 (+)EnsemblGRCh38hg38GRCh38
GRCh37127,080,076 - 7,105,520 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,950,255 - 6,955,404 (+)NCBINCBI36Build 36hg18NCBI36
Celera128,700,963 - 8,706,185 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,938,409 - 6,943,631 (+)NCBIHuRef
CHM1_1127,078,897 - 7,084,119 (+)NCBICHM1_1
T2T-CHM13v2.0126,984,388 - 7,010,891 (+)NCBIT2T-CHM13v2.0
Emg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,195,545 - 159,203,826 (-)NCBIGRCr8
mRatBN7.24157,509,258 - 157,517,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,509,277 - 157,517,540 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,737,748 - 163,746,028 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,520,654 - 159,528,933 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,162,220 - 158,170,500 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,222,366 - 157,230,647 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,222,385 - 157,230,647 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,239,962 - 224,248,243 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,826,925 - 160,835,206 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14161,072,842 - 161,080,012 (-)NCBI
Celera4146,247,921 - 146,256,202 (-)NCBICelera
Cytogenetic Map4q42NCBI
Emg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,563,864 - 4,570,809 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,563,864 - 4,570,809 (+)NCBIChiLan1.0ChiLan1.0
EMG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,536,820 - 12,542,053 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,533,579 - 12,538,816 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,102,619 - 7,108,594 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1127,018,291 - 7,023,807 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl127,018,291 - 7,023,807 (+)Ensemblpanpan1.1panPan2
EMG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,069,089 - 38,075,577 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,068,231 - 38,076,300 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,541,114 - 8,547,601 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,421,686 - 38,428,179 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,421,686 - 38,428,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,296,590 - 38,303,061 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,337,556 - 38,344,041 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,019,877 - 8,026,362 (+)NCBIUU_Cfam_GSD_1.0
Emg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,179,680 - 102,186,891 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709845,633 - 854,976 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936709847,229 - 854,471 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EMG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,745,476 - 63,751,469 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,746,326 - 63,751,469 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,182,467 - 66,187,610 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EMG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,004,507 - 7,009,702 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl117,004,645 - 7,009,527 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,206,934 - 1,213,103 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Emg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,605,126 - 3,611,108 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,605,114 - 3,611,108 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Emg1
213 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:396
Count of miRNA genes:274
Interacting mature miRNAs:304
Transcripts:ENSMUST00000004379, ENSMUST00000125795, ENSMUST00000141251, ENSMUST00000142187
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449436Pas17_mpulmonary adenoma susceptibility 17 (mouse)6124334273145601739Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103754405136400690Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698908709132916997Mouse
1301083Bhr5_mbronchial hyperresponsiveness 5 (mouse)Not determined6115694477132578150Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698219814132219938Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4140980Mvwf2_mmodifier of von Willebrand factor 2 (mouse)Not determined114345693145601739Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1301509Sluc3_msusceptibility to lung cancer 3 (mouse)Not determined6104480321127019938Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699132089133132228Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
10043891Tilss4_mTNF-induced lethal shock susceptibility 3 (mouse)Not determined6112246918125333748Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690772571124772807Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698694477132694676Mouse
10412207Cypr5_mcytokine production 5 (mouse)Not determined6110815180144815323Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696324286130324483Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
13463481Mcvq14_mmean corpuscular volume QTL 14 (mouse)6111142448145142541Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141064Ath37_matherosclerosis 37 (mouse)Not determined6116641858128495988Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104480321136400690Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined694981612128981699Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696324286130324483Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001409781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA185226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC002397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC164157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB948801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000004379   ⟹   ENSMUSP00000004379
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,681,344 - 124,689,141 (-)Ensembl
GRCm38.p6 Ensembl6124,704,381 - 124,712,178 (-)Ensembl
Ensembl Acc Id: ENSMUST00000125795
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,681,345 - 124,682,622 (-)Ensembl
GRCm38.p6 Ensembl6124,704,382 - 124,705,659 (-)Ensembl
Ensembl Acc Id: ENSMUST00000141251
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,681,914 - 124,689,104 (-)Ensembl
GRCm38.p6 Ensembl6124,704,951 - 124,712,141 (-)Ensembl
Ensembl Acc Id: ENSMUST00000142187
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,681,421 - 124,689,032 (-)Ensembl
GRCm38.p6 Ensembl6124,704,458 - 124,712,069 (-)Ensembl
Ensembl Acc Id: ENSMUST00000203238   ⟹   ENSMUSP00000144730
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,682,123 - 124,689,020 (-)Ensembl
GRCm38.p6 Ensembl6124,705,160 - 124,712,057 (-)Ensembl
Ensembl Acc Id: ENSMUST00000204334
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6124,681,048 - 124,685,376 (-)Ensembl
GRCm38.p6 Ensembl6124,704,085 - 124,708,413 (-)Ensembl
RefSeq Acc Id: NM_001409781   ⟹   NP_001396710
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,681,344 - 124,689,118 (-)NCBI
RefSeq Acc Id: NM_001409782   ⟹   NP_001396711
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,681,344 - 124,689,118 (-)NCBI
RefSeq Acc Id: NM_001409783   ⟹   NP_001396712
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,681,344 - 124,689,118 (-)NCBI
RefSeq Acc Id: NM_001409784   ⟹   NP_001396713
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,681,344 - 124,689,118 (-)NCBI
RefSeq Acc Id: NM_001409785   ⟹   NP_001396714
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,681,344 - 124,689,118 (-)NCBI
RefSeq Acc Id: NM_001409786   ⟹   NP_001396715
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,681,344 - 124,689,118 (-)NCBI
RefSeq Acc Id: NM_013536   ⟹   NP_038564
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396124,681,344 - 124,689,118 (-)NCBI
GRCm386124,704,370 - 124,712,178 (-)ENTREZGENE
MGSCv376124,654,388 - 124,662,196 (-)RGD
Celera6126,386,095 - 126,393,903 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_038564   ⟸   NM_013536
- Peptide Label: isoform 1
- UniProtKB: O35130 (UniProtKB/Swiss-Prot),   Q542P8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000144730   ⟸   ENSMUST00000203238
Ensembl Acc Id: ENSMUSP00000004379   ⟸   ENSMUST00000004379
RefSeq Acc Id: NP_001396713   ⟸   NM_001409784
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001396710   ⟸   NM_001409781
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001396711   ⟸   NM_001409782
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001396714   ⟸   NM_001409785
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001396715   ⟸   NM_001409786
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001396712   ⟸   NM_001409783
- Peptide Label: isoform 4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35130-F1-model_v2 AlphaFold O35130 1-244 view protein structure

Promoters
RGD ID:6839224
Promoter ID:MM_KWN:47551
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B6,   Spleen
Transcripts:OTTMUST00000057565
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366124,655,241 - 124,656,642 (-)MPROMDB
RGD ID:6839238
Promoter ID:MM_KWN:47552
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000100958,   NM_007531,   NM_013536,   OTTMUST00000048977,   OTTMUST00000048978,   OTTMUST00000048980,   OTTMUST00000057563,   OTTMUST00000057564,   OTTMUST00000067270,   OTTMUST00000067271,   UC009DRH.1,   UC009DRI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366124,662,026 - 124,663,437 (-)MPROMDB
RGD ID:6890974
Promoter ID:EPDNEW_M8936
Type:multiple initiation site
Name:Emg1_1
Description:Mus musculus EMG1 N1-specific pseudouridine methyltransferase, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8937  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386124,712,054 - 124,712,114EPDNEW
RGD ID:6890972
Promoter ID:EPDNEW_M8937
Type:initiation region
Name:Emg1_2
Description:Mus musculus EMG1 N1-specific pseudouridine methyltransferase, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8936  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386124,712,155 - 124,712,215EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1315195 AgrOrtholog
Ensembl Genes ENSMUSG00000004268 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000004379 ENTREZGENE
  ENSMUST00000004379.8 UniProtKB/Swiss-Prot
  ENSMUST00000203238.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Alpha/beta_knot_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rbsml_bgen_MeTrfase_EMG1/NEP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  tRNA_m1G_MTases_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14791 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1315195 ENTREZGENE
NCBI Gene 14791 ENTREZGENE
PANTHER PTHR12636 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EMG1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Emg1 PhenoGen
Superfamily-SCOP SSF75217 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUL6_MOUSE UniProtKB/TrEMBL
  NEP1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q542P8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-29 Emg1  EMG1 N1-specific pseudouridine methyltransferase    EMG1 nucleolar protein homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED