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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | KEL | Human | 1,2-dichloroethane | decreases expression | ISO | Kel (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of KEL mRNA | CTD | PMID:28960355 | KEL | Human | 17beta-estradiol | increases expression | ISO | Kel (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of KEL mRNA | CTD | PMID:32145629 | KEL | Human | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Kel (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | KEL | Human | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Kel (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | KEL | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Kel (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KEL mRNA | CTD | PMID:19465110 | KEL | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Kel (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of KEL mRNA | CTD | PMID:21570461 | KEL | Human | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | ISO | Kel (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | KEL | Human | 2-butoxyethanol | increases expression | ISO | Kel (Mus musculus) | 6480464 | n-butoxyethanol results in increased expression of KEL mRNA | CTD | PMID:19812364 | KEL | Human | 6-propyl-2-thiouracil | decreases expression | ISO | Kel (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of KEL mRNA | CTD | PMID:24780913 | KEL | Human | acetamide | decreases expression | ISO | Kel (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of KEL mRNA | CTD | PMID:31881176 | KEL | Human | acrylamide | decreases expression | ISO | Kel (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of KEL mRNA | CTD | PMID:28959563 | KEL | Human | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of KEL mRNA | CTD | PMID:33212167 | KEL | Human | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of KEL exon and Benzo(a)pyrene results in increased methylation of KEL promoter | CTD | PMID:27901495 | KEL | Human | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of KEL 3' UTR | CTD | PMID:27901495 | KEL | Human | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Kel (Mus musculus) | 6480464 | Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA] | CTD | PMID:33484791 | KEL | Human | bis(2-ethylhexyl) phthalate | increases expression | ISO | Kel (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of KEL mRNA | CTD | PMID:34319233 | KEL | Human | bis(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in decreased expression of KEL mRNA | CTD | PMID:31163220 | KEL | Human | bisphenol A | decreases expression | ISO | Kel (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of KEL mRNA | CTD | PMID:25181051 | KEL | Human | bisphenol A | increases expression | ISO | Kel (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of KEL mRNA | CTD | PMID:32145629 | KEL | Human | C60 fullerene | decreases expression | ISO | Kel (Rattus norvegicus) | 6480464 | fullerene C60 results in decreased expression of KEL mRNA | CTD | PMID:19167457 | KEL | Human | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to KEL gene] | CTD | PMID:28238834 | KEL | Human | chloroethene | increases expression | ISO | Kel (Mus musculus) | 6480464 | Vinyl Chloride results in increased expression of KEL mRNA | CTD | PMID:18579281 | KEL | Human | chlorpyrifos | decreases expression | ISO | Kel (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of KEL mRNA | CTD | PMID:37019170 | KEL | Human | copper atom | increases expression | ISO | Kel (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of KEL mRNA | CTD | PMID:26033743 | KEL | Human | copper atom | multiple interactions | ISO | Kel (Rattus norvegicus) | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of KEL mRNA | CTD | PMID:26033743 | KEL | Human | copper(0) | multiple interactions | ISO | Kel (Rattus norvegicus) | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of KEL mRNA | CTD | PMID:26033743 | KEL | Human | copper(0) | increases expression | ISO | Kel (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of KEL mRNA | CTD | PMID:26033743 | KEL | Human | Cuprizon | increases expression | ISO | Kel (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of KEL mRNA | CTD | PMID:26577399 | KEL | Human | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of KEL mRNA | CTD | PMID:29803840 | KEL | Human | ethyl methanesulfonate | increases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in increased expression of KEL mRNA | CTD | PMID:23649840 | KEL | Human | formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of KEL mRNA | CTD | PMID:23649840 | KEL | Human | genistein | decreases expression | ISO | Kel (Mus musculus) | 6480464 | Genistein results in decreased expression of KEL mRNA | CTD | PMID:32186404 | KEL | Human | methimazole | decreases expression | ISO | Kel (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of KEL mRNA | CTD | PMID:30047161 | KEL | Human | methyl methanesulfonate | increases expression | EXP | | 6480464 | Methyl Methanesulfonate results in increased expression of KEL mRNA | CTD | PMID:23649840 | KEL | Human | nitrofen | increases expression | ISO | Kel (Rattus norvegicus) | 6480464 | nitrofen results in increased expression of KEL mRNA | CTD | PMID:33484710 | KEL | Human | oxaliplatin | decreases expression | ISO | Kel (Rattus norvegicus) | 6480464 | oxaliplatin results in decreased expression of KEL mRNA | CTD | PMID:25729387 | KEL | Human | oxaliplatin | multiple interactions | ISO | Kel (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of KEL mRNA | CTD | PMID:25729387 | KEL | Human | paracetamol | affects expression | ISO | Kel (Mus musculus) | 6480464 | Acetaminophen affects the expression of KEL mRNA | CTD | PMID:17562736 | KEL | Human | PCB138 | multiple interactions | ISO | Kel (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | KEL | Human | phosphoramidon | multiple interactions | EXP | | 6480464 | KEL protein alternative form binds to and affects the metabolism of phosphoramidon | CTD | PMID:15769748 | KEL | Human | potassium dichromate | increases expression | ISO | Kel (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of KEL mRNA | CTD | PMID:23608068 | KEL | Human | streptozocin | multiple interactions | ISO | Kel (Mus musculus) | 6480464 | [Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA and Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA] | CTD | PMID:33484791 | KEL | Human | topotecan | multiple interactions | ISO | Kel (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of KEL mRNA | CTD | PMID:25729387 | KEL | Human | topotecan | decreases expression | ISO | Kel (Rattus norvegicus) | 6480464 | Topotecan results in decreased expression of KEL mRNA | CTD | PMID:25729387 | |