Krtap3-3 (keratin associated protein 3-3) - Rat Genome Database

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Gene: Krtap3-3 (keratin associated protein 3-3) Mus musculus
Analyze
Symbol: Krtap3-3
Name: keratin associated protein 3-3
RGD ID: 1316738
MGI Page MGI
Description: Is expressed in central nervous system and retina. Orthologous to several human genes including KRTAP3-2 (keratin associated protein 3-2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2310020D06Rik; KAP3; KAP3.3; keratin associated protein 3-2; keratin-associated protein 3-2; keratin-associated protein 3-3; KRTAP; Krtap3-2; KRTAP3.3
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,440,958 - 99,441,689 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,440,956 - 99,441,691 (-)EnsemblGRCm39 Ensembl
GRCm381199,550,132 - 99,550,863 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1199,550,130 - 99,550,865 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,411,446 - 99,412,177 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,329,753 - 100,330,582 (-)NCBIMGSCv36mm8
MGSCv361199,366,222 - 99,366,953 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1162.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18721477  


Genomics

Comparative Map Data
Krtap3-3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,440,958 - 99,441,689 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,440,956 - 99,441,691 (-)EnsemblGRCm39 Ensembl
GRCm381199,550,132 - 99,550,863 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1199,550,130 - 99,550,865 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,411,446 - 99,412,177 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,329,753 - 100,330,582 (-)NCBIMGSCv36mm8
MGSCv361199,366,222 - 99,366,953 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1162.92NCBI
KRTAP3-3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381740,993,430 - 40,994,164 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1740,993,430 - 40,994,164 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,149,682 - 39,150,416 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,403,208 - 36,403,911 (-)NCBINCBI36Build 36hg18NCBI36
Celera1735,811,286 - 35,811,989 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1734,944,705 - 34,945,408 (-)NCBIHuRef
CHM1_11739,385,416 - 39,386,119 (-)NCBICHM1_1
T2T-CHM13v2.01741,857,895 - 41,858,629 (-)NCBIT2T-CHM13v2.0
Krtap3-3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81085,007,606 - 85,007,905 (-)NCBIGRCr8
mRatBN7.21084,511,459 - 84,511,758 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1084,517,977 - 84,518,988 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1084,511,092 - 84,511,812 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01087,468,002 - 87,468,697 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1087,467,991 - 87,468,711 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01087,264,855 - 87,265,154 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41088,497,766 - 88,498,065 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11088,511,768 - 88,519,640 (-)NCBI
Celera1083,250,727 - 83,251,422 (-)NCBICelera
Cytogenetic Map10q31NCBI
LOC103783813
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21923,957,823 - 23,958,685 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11725,848,415 - 25,849,157 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01716,289,544 - 16,290,404 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11716,515,015 - 16,515,312 (+)NCBIpanpan1.1PanPan1.1panPan2
LOC102151831
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,687,965 - 21,688,695 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha921,161,381 - 21,162,085 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0922,474,934 - 22,475,638 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1921,255,684 - 21,256,388 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0921,514,544 - 21,515,248 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0921,638,381 - 21,639,085 (+)NCBIUU_Cfam_GSD_1.0
LOC110256008
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11221,469,579 - 21,470,654 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in Krtap3-3
36 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:177
Count of miRNA genes:133
Interacting mature miRNAs:163
Transcripts:ENSMUST00000092700
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse

Markers in Region
UniSTS:490511  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381199,550,441 - 99,550,859UniSTSGRCm38
MGSCv371199,411,755 - 99,412,173UniSTSGRCm37
Cytogenetic Map11DUniSTS
UniSTS:495527  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381199,550,364 - 99,550,831UniSTSGRCm38
MGSCv371199,411,678 - 99,412,145UniSTSGRCm37
Cytogenetic Map11DUniSTS


Expression


Sequence


Ensembl Acc Id: ENSMUST00000092700   ⟹   ENSMUSP00000090374
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1199,440,956 - 99,441,691 (-)Ensembl
GRCm38.p6 Ensembl1199,550,130 - 99,550,865 (-)Ensembl
RefSeq Acc Id: NM_025524   ⟹   NP_079800
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391199,440,958 - 99,441,689 (-)NCBI
GRCm381199,550,132 - 99,550,863 (-)ENTREZGENE
MGSCv371199,411,446 - 99,412,177 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_079800   ⟸   NM_025524
- UniProtKB: Q9D7P0 (UniProtKB/Swiss-Prot),   Q9CPW1 (UniProtKB/Swiss-Prot),   Q9D638 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000090374   ⟸   ENSMUST00000092700

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D638-F1-model_v2 AlphaFold Q9D638 1-99 view protein structure
AF-Q9D7P0-F1-model_v2 AlphaFold Q9D7P0 1-99 view protein structure

Promoters
RGD ID:8676582
Promoter ID:EPDNEW_M16321
Type:single initiation site
Name:Krtap3-3_1
Description:Mus musculus keratin associated protein 3-3 (Krtap3-3), mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381199,550,863 - 99,550,923EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913630 AgrOrtholog
Ensembl Genes ENSMUSG00000069721 UniProtKB/Swiss-Prot
  ENSMUSG00000069722 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000092699.3 UniProtKB/Swiss-Prot
  ENSMUST00000092700 ENTREZGENE
  ENSMUST00000092700.5 UniProtKB/Swiss-Prot
InterPro Keratin_matx UniProtKB/Swiss-Prot
KEGG Report mmu:66380 UniProtKB/Swiss-Prot
  mmu:66708 UniProtKB/Swiss-Prot
MGD MGI:1913630 ENTREZGENE
NCBI Gene 66380 ENTREZGENE
PANTHER KERATIN-ASSOCIATED PROTEIN 3-3 UniProtKB/Swiss-Prot
  PTHR23260 UniProtKB/Swiss-Prot
Pfam Keratin_matx UniProtKB/Swiss-Prot
PhenoGen Krtap3-3 PhenoGen
UniProt KRA32_MOUSE UniProtKB/Swiss-Prot
  KRA33_MOUSE UniProtKB/Swiss-Prot
  Q9CPW1 ENTREZGENE
  Q9D638 ENTREZGENE
  Q9D7P0 ENTREZGENE
UniProt Secondary Q9CPW1 UniProtKB/Swiss-Prot