Cpne7 (copine VII) - Rat Genome Database

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Gene: Cpne7 (copine VII) Mus musculus
Analyze
Symbol: Cpne7
Name: copine VII
RGD ID: 1316678
MGI Page MGI
Description: Predicted to enable calcium-dependent phospholipid binding activity. Predicted to be involved in cellular response to calcium ion. Is active in synapse. Is expressed in central nervous system; jaw; and nose. Orthologous to human CPNE7 (copine 7).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AW047065; copine 7 protein; copine-7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,844,054 - 123,861,924 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,844,113 - 123,861,921 (+)EnsemblGRCm39 Ensembl
GRCm388123,117,313 - 123,135,185 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,117,374 - 123,135,182 (+)EnsemblGRCm38mm10GRCm38
MGSCv378125,641,274 - 125,659,085 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368126,003,547 - 126,021,272 (+)NCBIMGSCv36mm8
Celera8127,354,880 - 127,372,744 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map872.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
membrane  (IEA)
nucleus  (ISO)
plasma membrane  (IBA,ISO)
synapse  (EXP,IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9430674   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16602821   PMID:20818386  
PMID:21267068   PMID:21873635   PMID:24952961   PMID:30734591   PMID:30863901   PMID:32283105   PMID:32325033   PMID:35660742   PMID:38105557   PMID:38355793  


Genomics

Comparative Map Data
Cpne7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,844,054 - 123,861,924 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,844,113 - 123,861,921 (+)EnsemblGRCm39 Ensembl
GRCm388123,117,313 - 123,135,185 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,117,374 - 123,135,182 (+)EnsemblGRCm38mm10GRCm38
MGSCv378125,641,274 - 125,659,085 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368126,003,547 - 126,021,272 (+)NCBIMGSCv36mm8
Celera8127,354,880 - 127,372,744 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map872.06NCBI
CPNE7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,575,758 - 89,597,246 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1689,575,758 - 89,597,246 (+)EnsemblGRCh38hg38GRCh38
GRCh371689,642,166 - 89,663,654 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,169,677 - 88,191,155 (+)NCBINCBI36Build 36hg18NCBI36
Build 341688,169,676 - 88,191,154NCBI
Celera1674,705,518 - 74,726,398 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1675,338,670 - 75,358,493 (+)NCBIHuRef
CHM1_11691,053,456 - 91,074,511 (+)NCBICHM1_1
T2T-CHM13v2.01695,656,186 - 95,677,486 (+)NCBIT2T-CHM13v2.0
Cpne7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,072,165 - 68,091,197 (+)NCBIGRCr8
mRatBN7.21951,164,316 - 51,182,676 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,166,034 - 51,182,677 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1957,961,280 - 57,977,864 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,641,026 - 58,657,595 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,859,881 - 60,876,466 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,929,555 - 55,946,251 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,929,609 - 55,946,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,634,960 - 66,651,622 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,449,428 - 53,466,072 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11953,454,423 - 53,470,317 (+)NCBI
Celera1950,401,641 - 50,418,280 (+)NCBICelera
Cytogenetic Map19q12NCBI
Cpne7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555413,159,818 - 3,170,428 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555413,159,485 - 3,170,304 (+)NCBIChiLan1.0ChiLan1.0
CPNE7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21899,359,606 - 99,381,701 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116105,276,736 - 105,298,863 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01670,327,952 - 70,349,898 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,937,091 - 89,951,891 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,936,172 - 89,955,115 (+)Ensemblpanpan1.1panPan2
CPNE7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,951,547 - 63,978,389 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,951,549 - 63,978,601 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha563,964,401 - 63,990,428 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,179,595 - 64,205,647 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,179,600 - 64,205,968 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,199,565 - 64,225,563 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,037,029 - 64,063,036 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,443,812 - 64,469,864 (-)NCBIUU_Cfam_GSD_1.0
Cpne7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,659,779 - 24,673,456 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641413,759 - 426,507 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936641413,331 - 426,514 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CPNE7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.16393,756 - 410,781 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CPNE7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,937,985 - 74,953,406 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666047557,511 - 572,149 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Cpne7
711 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:840
Count of miRNA genes:408
Interacting mature miRNAs:462
Transcripts:ENSMUST00000037900, ENSMUST00000123191, ENSMUST00000127431, ENSMUST00000131659, ENSMUST00000134235
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357494Obsty2_mobesity 2 (mouse)Not determined896245241129745061Mouse
4141435Fbtq3_mfemoral bone trait QTL 3 (mouse)Not determined8100965309130127694Mouse
12904960Gmmq6_mgastrocnemius muscle mass QTL 6 (mouse)8111481497130127694Mouse
11252141Fdr2_mfat response to dietary restriction 2 (mouse)898390634130127694Mouse
1302105Im1_mImmunoregulatory 1 (mouse)Not determined899828531130127694Mouse
12880431Fgf23lq2_mFGF23 serum level QTL 2 (mouse)897626632130127694Mouse
1301080Sluc9_msusceptibility to lung cancer 9 (mouse)Not determined899828531130127694Mouse
10412274Leci1_mleukocyte endothelial cell interactions 1 (mouse)Not determined8110415083130127694Mouse
26884375Skwq2_mskull length QTL 2, 5 week (mouse)8120726739130027694Mouse
12904938Edlmmq7_mextensor digitorum longus muscle mass QTL 7 (mouse)8111481497130127694Mouse
10412273Fcd1_mfunctional capillary density 1 (mouse)Not determined8110415083130127694Mouse
27226796Scvln16_msacral vertebrae length 2, 16 week (mouse)889726628130027694Mouse
14746994Manh65_mmandible shape 65 (mouse)8106489629130127694Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)874126628126826739Mouse
4141546Mrdq3_mmodifier of retinal degeneration QTL 3 (mouse)Not determined114439420126055880Mouse
1301316Dntcs1_mdental caries susceptibility 1 (mouse)Not determined8103443553127781786Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871740461124622354Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71740461124622354Mouse
1301481Lith11_mlithogenic gene 11 (mouse)Not determined898563635130127694Mouse
11532692Sluc38a_msusceptibility to lung cancer 38a (mouse)8105033977130127694Mouse
11532691Sluc38_msusceptibility to lung cancer 38 (mouse)8105033977130127694Mouse

Markers in Region
AW047065  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388123,134,948 - 123,135,084UniSTSGRCm38
MGSCv378125,658,848 - 125,658,984UniSTSGRCm37
Celera8127,372,507 - 127,372,643UniSTS
Cytogenetic Map8E1UniSTS
Whitehead/MRC_RH81428.09UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_170684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006530549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001778387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_387726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI550750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU079878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW047065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC119328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC137595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE864888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF458951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM946575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000037900   ⟹   ENSMUSP00000042159
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8123,844,117 - 123,861,921 (+)Ensembl
GRCm38.p6 Ensembl8123,117,378 - 123,135,182 (+)Ensembl
Ensembl Acc Id: ENSMUST00000123191
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8123,853,256 - 123,854,112 (+)Ensembl
GRCm38.p6 Ensembl8123,126,517 - 123,127,373 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127431
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8123,855,362 - 123,858,631 (+)Ensembl
GRCm38.p6 Ensembl8123,128,623 - 123,131,892 (+)Ensembl
Ensembl Acc Id: ENSMUST00000131659
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8123,844,186 - 123,861,921 (+)Ensembl
GRCm38.p6 Ensembl8123,117,447 - 123,135,182 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134235
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl8123,844,113 - 123,861,919 (+)Ensembl
GRCm38.p6 Ensembl8123,117,374 - 123,135,180 (+)Ensembl
RefSeq Acc Id: NM_170684   ⟹   NP_733785
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398123,844,113 - 123,861,924 (+)NCBI
GRCm388123,117,374 - 123,135,185 (+)NCBI
MGSCv378125,641,274 - 125,659,085 (+)RGD
Celera8127,354,880 - 127,372,744 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006530549   ⟹   XP_006530612
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398123,846,545 - 123,861,924 (+)NCBI
GRCm388123,119,806 - 123,135,185 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001778387
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398123,844,054 - 123,861,924 (+)NCBI
GRCm388123,117,313 - 123,135,185 (+)NCBI
Sequence:
RefSeq Acc Id: XR_387726
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm398123,844,057 - 123,861,924 (+)NCBI
GRCm388123,117,316 - 123,135,185 (+)NCBI
Sequence:
RefSeq Acc Id: NP_733785   ⟸   NM_170684
- UniProtKB: Q0VE82 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006530612   ⟸   XM_006530549
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000042159   ⟸   ENSMUST00000037900
Protein Domains
C2   Copine C-terminal   VWFA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q0VE82-F1-model_v2 AlphaFold Q0VE82 1-557 view protein structure

Promoters
RGD ID:8668547
Promoter ID:EPDNEW_M12305
Type:initiation region
Name:Cpne7_1
Description:Mus musculus copine VII , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm388123,117,453 - 123,117,513EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2142747 AgrOrtholog
Ensembl Genes ENSMUSG00000034796 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000037900 ENTREZGENE
  ENSMUST00000037900.9 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot
  3.40.50.410 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/Swiss-Prot
  C2_domain_sf UniProtKB/Swiss-Prot
  C2B_Copine UniProtKB/Swiss-Prot
  Copine UniProtKB/Swiss-Prot
  Copine UniProtKB/Swiss-Prot
  Copine UniProtKB/TrEMBL
  Copine UniProtKB/TrEMBL
  VWF_A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:102278 UniProtKB/Swiss-Prot
MGD MGI:2142747 ENTREZGENE
NCBI Gene 102278 ENTREZGENE
PANTHER COPINE-7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10857 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Copine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00168 UniProtKB/Swiss-Prot
PhenoGen Cpne7 PhenoGen
PROSITE PS50004 UniProtKB/Swiss-Prot
  VWFA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00239 UniProtKB/Swiss-Prot
  VWA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/Swiss-Prot
  SSF53300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CPNE7_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8BIJ1_MOUSE UniProtKB/TrEMBL
  Q8C019_MOUSE UniProtKB/TrEMBL