Ryr1 (ryanodine receptor 1, skeletal muscle) - Rat Genome Database

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Gene: Ryr1 (ryanodine receptor 1, skeletal muscle) Mus musculus
Analyze
Symbol: Ryr1
Name: ryanodine receptor 1, skeletal muscle
RGD ID: 1316414
MGI Page MGI
Description: Enables protease binding activity; ryanodine-sensitive calcium-release channel activity; and voltage-gated calcium channel activity. Involved in several processes, including cellular response to caffeine; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; and skeletal muscle fiber development. Acts upstream of or within muscle contraction and release of sequestered calcium ion into cytosol. Located in T-tubule; sarcoplasmic reticulum membrane; and smooth endoplasmic reticulum. Part of junctional membrane complex. Is expressed in several structures, including brain; embryo mesenchyme; endocrine gland; heart; and skeletal musculature. Used to study central core disease and malignant hyperthermia. Human ortholog(s) of this gene implicated in central core disease; malignant hyperthermia; and multiminicore disease. Orthologous to human RYR1 (ryanodine receptor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI528790; calcium release channel; R; ryanodine receptor 1; Ryr; RYR-1; s; skeletal muscle calcium release channel; skeletal muscle ryanodine receptor; skeletal muscle-type ryanodine receptor; skrr; type 1 ryanodine receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39728,702,765 - 28,824,599 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl728,702,769 - 28,824,604 (-)EnsemblGRCm39 Ensembl
GRCm38729,003,340 - 29,125,179 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl729,003,344 - 29,125,179 (-)EnsemblGRCm38mm10GRCm38
MGSCv37729,788,359 - 29,910,170 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36728,712,104 - 28,833,911 (-)NCBIMGSCv36mm8
Celera723,565,768 - 23,695,212 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map716.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
ankyloglossia  (ISO)
Aortic Coarctation  (ISO)
arthrogryposis multiplex congenita  (ISO)
atrial heart septal defect  (ISO)
Axial Myopathy, Late-Onset  (ISO)
Bronchomalacia  (ISO)
cardiomyopathy  (ISO)
caudal regression syndrome  (ISO)
centronuclear myopathy  (ISO)
clubfoot  (ISO)
Congenital Hip Dislocation  (ISO)
congenital muscular dystrophy  (ISO)
congenital myasthenic syndrome  (ISO)
congenital myasthenic syndrome 12  (ISO)
congenital myopathy  (ISO)
congenital myopathy 1A  (IAGP,ISO)
congenital myopathy 1B  (ISO)
congenital myopathy 4A  (ISO)
Congenital Neuromuscular Disease, with Uniform Type 1 Fiber  (ISO)
congenital structural myopathy  (ISO)
congestive heart failure  (IDA,ISO)
Developmental Disabilities  (ISO)
distal arthrogryposis  (ISO)
Dwarfism  (ISO)
Dyskinesias  (ISO)
dystonia  (ISO)
fetal akinesia deformation sequence syndrome  (ISO)
fetal akinesia deformation sequence syndrome 1  (ISO)
gastroesophageal reflux disease  (ISO)
genetic disease  (ISO)
glaucoma  (ISO)
GNE myopathy  (ISO)
Heart Block  (ISO)
Heat Stroke  (IMP)
Hereditary Motor Neuropathy with Myopathic Features  (ISO)
Hydrops Fetalis  (ISO)
intracranial vasospasm  (ISO)
isolated elevated serum creatine phosphokinase levels  (ISO)
King Denborough syndrome  (ISO)
Lead Poisoning  (ISO)
learning disability  (ISO)
Left Ventricular Hypertrophy  (ISO)
Malignant Fever  (ISO)
malignant hyperthermia  (IAGP,IMP,ISO)
Malignant Hypothermia  (ISO)
Mitochondrial Progressive Myopathy with Congenital Cataract, Hearing Loss, and Developmental Delay  (ISO)
Muscle Hypotonia  (ISO)
Muscle Weakness  (ISO)
muscular disease  (ISO)
Myalgia  (ISO)
myocardial infarction  (ISO)
myopathy  (ISO)
Myotonia  (ISO)
neuromuscular disease  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
osteochondrodysplasia  (ISO)
osteoporosis  (ISO)
panhypopituitarism  (ISO)
primary pulmonary hypertension  (ISO)
ptosis  (ISO)
pulmonary hypertension  (ISO)
renal cell carcinoma  (ISO)
Rhabdomyolysis  (ISO)
rigid spine muscular dystrophy 1  (ISO)
scoliosis  (ISO)
Ullrich congenital muscular dystrophy  (ISO)
ventricular septal defect  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP)
2,2',3,3',6,6'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-chloro-m-cresol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (ISO)
Ammothamnine  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
atrazine  (ISO)
baclofen  (EXP)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bicuculline  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
caffeine  (EXP,ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
CGP 52608  (ISO)
chlordecone  (EXP)
chlorpyrifos  (ISO)
choline  (EXP)
chrysene  (EXP)
Cuprizon  (ISO)
dantrolene  (ISO)
DDE  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (EXP)
dimethylarsinic acid  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
ethanol  (EXP)
fenvalerate  (EXP)
flubendiamide  (EXP)
folic acid  (EXP)
graphite  (EXP)
halothane  (EXP,ISO)
L-methionine  (EXP)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methylarsonic acid  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
paracetamol  (EXP)
perfluorooctanoic acid  (ISO)
pioglitazone  (EXP)
raloxifene  (ISO)
ryanodine  (EXP,ISO)
SCH 23390  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
sotorasib  (ISO)
spermine  (EXP)
tacrolimus hydrate  (EXP)
tamoxifen  (ISO)
tetracaine  (EXP)
titanium dioxide  (EXP)
trametinib  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
triptonide  (EXP)
valproic acid  (EXP,ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axial skeleton morphology  (IAGP)
abnormal body temperature homeostasis  (IAGP)
abnormal calcium ion homeostasis  (IAGP)
abnormal cell physiology  (IAGP)
abnormal coronary artery morphology  (IAGP)
abnormal dermal layer morphology  (IAGP)
abnormal diaphragm morphology  (IAGP)
abnormal interventricular groove morphology  (IAGP)
abnormal limb morphology  (IAGP)
abnormal locomotor behavior  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal mitochondrial shape  (IAGP)
abnormal muscle contractility  (IAGP)
abnormal muscle development  (IAGP)
abnormal muscle electrophysiology  (IAGP)
abnormal muscle fiber morphology  (IAGP)
abnormal muscle physiology  (IAGP)
abnormal physiological response to xenobiotic  (IAGP)
abnormal posture  (IAGP)
abnormal potassium ion homeostasis  (IAGP)
abnormal rib morphology  (IAGP)
abnormal sarcomere morphology  (IAGP)
abnormal sarcoplasmic reticulum morphology  (IAGP)
abnormal skeletal muscle fiber morphology  (IAGP)
abnormal skeletal muscle morphology  (IAGP)
abnormal skin condition  (IAGP)
abnormal soleus morphology  (IAGP)
abnormal spine curvature  (IAGP)
abnormal thoracic cage shape  (IAGP)
abnormal Z line morphology  (IAGP)
acidemia  (IAGP)
centrally nucleated skeletal muscle fibers  (IAGP)
cleft secondary palate  (IAGP)
cyanosis  (IAGP)
decreased birth body size  (IAGP)
decreased birth weight  (IAGP)
decreased body length  (IAGP)
decreased body weight  (IAGP)
decreased grip strength  (IAGP)
decreased skeletal muscle fiber diameter  (IAGP)
decreased skeletal muscle fiber number  (IAGP)
decreased skeletal muscle fiber size  (IAGP)
decreased skeletal muscle mass  (IAGP)
decreased total body fat amount  (IAGP)
delayed bone ossification  (IAGP)
delayed heart development  (IAGP)
domed cranium  (IAGP)
edema  (IAGP)
enhanced behavioral response to xenobiotic  (IAGP)
fetal growth retardation  (IAGP)
hindlimb paralysis  (IAGP)
hypercapnia  (IAGP)
impaired muscle contractility  (IAGP)
impaired muscle relaxation  (IAGP)
impaired skeletal muscle contractility  (IAGP)
increased body weight  (IAGP)
increased brown adipose tissue amount  (IAGP)
increased circulating potassium level  (IAGP)
increased core body temperature  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased pulmonary respiratory rate  (IAGP)
increased respiratory quotient  (IEA)
increased sensitivity to induced morbidity/mortality  (IAGP)
increased sensitivity to xenobiotic induced morbidity/mortality  (IAGP)
increased spleen weight  (IEA)
increased susceptibility to malignant hyperthermia  (IAGP)
increased variability of skeletal muscle fiber size  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
muscle tetany  (IAGP)
muscle twitch  (IAGP)
muscle weakness  (IAGP)
myopathy  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no spontaneous movement  (IAGP)
omphalocele  (IAGP)
ostium primum atrial septal defect  (IAGP)
ostium secundum atrial septal defect  (IAGP)
paralysis  (IAGP)
pectus excavatum  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IEA)
respiratory distress  (IAGP)
respiratory failure  (IAGP)
skeletal muscle degeneration  (IAGP)
skin edema  (IAGP)
thin ribs  (IAGP)
tight skin  (IAGP)
translucent skin  (IAGP)
underdeveloped hair follicles  (IAGP)
unresponsive to tactile stimuli  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Skeletal muscle dysfunction in idiopathic pulmonary arterial hypertension. Batt J, etal., Am J Respir Cell Mol Biol. 2014 Jan;50(1):74-86. doi: 10.1165/rcmb.2012-0506OC.
2. Stretch-induced Ca2+ signalling in vascular smooth muscle cells depends on Ca2+ store segregation. Gilbert G, etal., Cardiovasc Res. 2014 Jul 15;103(2):313-23. doi: 10.1093/cvr/cvu069. Epub 2014 Apr 1.
3. Common variants in RYR1 are associated with left ventricular hypertrophy assessed by electrocardiogram. Hong KW, etal., Eur Heart J. 2012 May;33(10):1250-6. doi: 10.1093/eurheartj/ehr267. Epub 2011 Aug 9.
4. Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure. Kushnir A, etal., Circulation. 2018 Sep 11;138(11):1144-1154. doi: 10.1161/CIRCULATIONAHA.117.032703.
5. Ryanodine receptors: structure, expression, molecular details, and function in calcium release. Lanner JT, etal., Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a003996. doi: 10.1101/cshperspect.a003996. Epub 2010 Oct 20.
6. Malignant hyperthermia, environmental heat stress, and intracellular calcium dysregulation in a mouse model expressing the p.G2435R variant of RYR1. Lopez JR, etal., Br J Anaesth. 2018 Oct;121(4):953-961. doi: 10.1016/j.bja.2018.07.008. Epub 2018 Aug 10.
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Search for genetic variants in the ryanodine receptor 1 gene in patients with symptomatic cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Rueffert H, etal., Neurocrit Care. 2011 Dec;15(3):410-5. doi: 10.1007/s12028-011-9542-7.
15. Ryanodine receptor 1 mediated dexamethasone-induced chondrodysplasia in fetal rats. Wang YZ, etal., Biochim Biophys Acta Mol Cell Res. 2020 Oct;1867(10):118791. doi: 10.1016/j.bbamcr.2020.118791. Epub 2020 Jun 30.
16. Defects in ryanodine receptor calcium release in skeletal muscle from post-myocardial infarct rats. Ward CW, etal., FASEB J. 2003 Aug;17(11):1517-9. doi: 10.1096/fj.02-1083fje. Epub 2003 Jun 3.
17. ECG conduction disturbances and ryanodine receptor expression levels in occupational lead exposure workers. Xie J, etal., Occup Environ Med. 2019 Mar;76(3):151-156. doi: 10.1136/oemed-2018-105463. Epub 2019 Jan 19.
18. A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke. Yamazawa T, etal., Nat Commun. 2021 Jul 13;12(1):4293. doi: 10.1038/s41467-021-24644-1.
19. [Therapeutic effects of novel type1 ryanodine receptor inhibitor on skeletal muscle diseases]. Yamazawa T, etal., Nihon Yakurigaku Zasshi. 2022;157(1):15-22. doi: 10.1254/fpj.21068.
Additional References at PubMed
PMID:1315127   PMID:1774073   PMID:1967823   PMID:1970795   PMID:2300206   PMID:2421615   PMID:3161450   PMID:4600883   PMID:7515481   PMID:7621815   PMID:7635066   PMID:7724570  
PMID:7832748   PMID:7876312   PMID:7931345   PMID:7959768   PMID:8288260   PMID:8598910   PMID:8618963   PMID:8626432   PMID:8812484   PMID:8910220   PMID:8943043   PMID:9054435  
PMID:9124414   PMID:9192302   PMID:9204703   PMID:9242641   PMID:9384575   PMID:9461216   PMID:9472036   PMID:9480761   PMID:9489997   PMID:9799464   PMID:9817784   PMID:9986730  
PMID:10213392   PMID:10349636   PMID:10444070   PMID:10473538   PMID:10736313   PMID:10788707   PMID:11042159   PMID:11076861   PMID:11159936   PMID:11217851   PMID:11500519   PMID:11784029  
PMID:11818962   PMID:11852053   PMID:11860456   PMID:12023238   PMID:12364321   PMID:12376096   PMID:12414688   PMID:12466851   PMID:12477932   PMID:12486242   PMID:12640042   PMID:12642598  
PMID:12654335   PMID:12704193   PMID:12732639   PMID:12954602   PMID:14592808   PMID:14592949   PMID:14610273   PMID:14660561   PMID:14672973   PMID:15033925   PMID:15102471   PMID:15280431  
PMID:15289441   PMID:15313613   PMID:15381065   PMID:15469935   PMID:15536090   PMID:15619962   PMID:15894801   PMID:15972723   PMID:16141072   PMID:16141073   PMID:16246297   PMID:16284304  
PMID:16357209   PMID:16484216   PMID:16602821   PMID:16737973   PMID:16762927   PMID:16844763   PMID:16920191   PMID:17033962   PMID:17074386   PMID:17118445   PMID:17122579   PMID:17158949  
PMID:17520475   PMID:17925380   PMID:17942409   PMID:18003898   PMID:18089560   PMID:18206662   PMID:18215135   PMID:18268335   PMID:18313230   PMID:18322139   PMID:18394989   PMID:18403125  
PMID:18434328   PMID:18434746   PMID:18488020   PMID:18556650   PMID:18643873   PMID:18650434   PMID:18663468   PMID:18676612   PMID:18772199   PMID:18927079   PMID:19011160   PMID:19033399  
PMID:19131108   PMID:19198614   PMID:19246389   PMID:19398467   PMID:19549818   PMID:19802526   PMID:19959667   PMID:19966218   PMID:20207743   PMID:20479108   PMID:20479110   PMID:20519450  
PMID:20576841   PMID:20926377   PMID:20955474   PMID:20961389   PMID:20978128   PMID:21150295   PMID:21156754   PMID:21262876   PMID:21267068   PMID:21289290   PMID:21441923   PMID:21575570  
PMID:21646399   PMID:21784520   PMID:21803290   PMID:21803293   PMID:21825032   PMID:21858002   PMID:21873635   PMID:21896730   PMID:21933672   PMID:21969454   PMID:22036948   PMID:22131268  
PMID:22139840   PMID:22203976   PMID:22231556   PMID:22355118   PMID:22411552   PMID:22504960   PMID:22505613   PMID:22853897   PMID:22939628   PMID:22962299   PMID:23070698   PMID:23071115  
PMID:23152933   PMID:23159934   PMID:23223241   PMID:23247505   PMID:23278119   PMID:23308296   PMID:23413940   PMID:23454728   PMID:23463619   PMID:23482488   PMID:23509717   PMID:23695157  
PMID:23785297   PMID:23798496   PMID:23818578   PMID:23918386   PMID:23992453   PMID:24123915   PMID:24143248   PMID:24194600   PMID:24325401   PMID:24509862   PMID:24703692   PMID:24962901  
PMID:25239916   PMID:25384984   PMID:25548159   PMID:25564733   PMID:25619131   PMID:25640239   PMID:25874477   PMID:26025922   PMID:26114725   PMID:26134413   PMID:26462735   PMID:26494785  
PMID:26575622   PMID:26831464   PMID:26910427   PMID:27150455   PMID:27382027   PMID:27621462   PMID:27655403   PMID:27802169   PMID:27841305   PMID:28465322   PMID:28724790   PMID:28831123  
PMID:29130937   PMID:29543863   PMID:29701772   PMID:29949772   PMID:30071129   PMID:30311737   PMID:30420428   PMID:30563862   PMID:30689883   PMID:30770808   PMID:30786075   PMID:30870432  
PMID:31044239   PMID:31107960   PMID:31199454   PMID:31607937   PMID:31804576   PMID:32242214   PMID:32325033   PMID:32367593   PMID:32499372   PMID:32506037   PMID:32693782   PMID:32826313  
PMID:32883967   PMID:32994313   PMID:33037202   PMID:33065384   PMID:33176865   PMID:33230847   PMID:34893614   PMID:34924936   PMID:34938155   PMID:35046046   PMID:35081489   PMID:35238775  
PMID:36010545   PMID:36200983   PMID:36862731  


Genomics

Comparative Map Data
Ryr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39728,702,765 - 28,824,599 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl728,702,769 - 28,824,604 (-)EnsemblGRCm39 Ensembl
GRCm38729,003,340 - 29,125,179 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl729,003,344 - 29,125,179 (-)EnsemblGRCm38mm10GRCm38
MGSCv37729,788,359 - 29,910,170 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36728,712,104 - 28,833,911 (-)NCBIMGSCv36mm8
Celera723,565,768 - 23,695,212 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map716.94NCBI
RYR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381938,433,691 - 38,587,564 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1938,433,691 - 38,595,273 (+)EnsemblGRCh38hg38GRCh38
GRCh371938,924,331 - 39,078,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361943,616,180 - 43,770,044 (+)NCBINCBI36Build 36hg18NCBI36
Build 341943,616,179 - 43,770,012NCBI
Celera1935,726,452 - 35,880,238 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1935,371,495 - 35,526,332 (+)NCBIHuRef
CHM1_11938,924,701 - 39,079,134 (+)NCBICHM1_1
T2T-CHM13v2.01941,235,876 - 41,391,545 (+)NCBIT2T-CHM13v2.0
Ryr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2184,292,578 - 84,423,799 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl184,292,578 - 84,423,812 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0187,959,596 - 88,066,252 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl187,959,712 - 88,066,101 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0189,135,622 - 89,241,311 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4184,116,098 - 84,254,503 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera178,682,691 - 78,812,242 (-)NCBICelera
Cytogenetic Map1q21NCBI
Ryr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955468879,951 - 1,000,036 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955468879,807 - 1,000,118 (-)NCBIChiLan1.0ChiLan1.0
RYR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11946,595,023 - 46,752,872 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01935,527,466 - 35,685,446 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11944,099,196 - 44,256,470 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1944,106,036 - 44,256,327 (+)Ensemblpanpan1.1panPan2
RYR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11114,461,350 - 114,579,577 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1114,461,348 - 114,579,493 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1113,865,988 - 113,983,252 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01115,063,307 - 115,181,223 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1115,063,305 - 115,204,391 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11114,636,271 - 114,754,225 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01114,253,994 - 114,371,830 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01115,292,565 - 115,410,455 (-)NCBIUU_Cfam_GSD_1.0
Ryr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934913,020,295 - 13,133,060 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368011,185,733 - 1,298,289 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049368011,185,615 - 1,298,416 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RYR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl647,343,768 - 47,458,458 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1647,339,759 - 47,458,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2642,840,240 - 42,960,110 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q1.2NCBI
RYR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1633,080,443 - 33,234,478 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl633,080,758 - 33,213,788 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607311,024,332 - 11,181,890 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ryr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479411,888,289 - 12,004,314 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479411,888,211 - 12,004,457 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ryr1
4322 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:393
Count of miRNA genes:190
Interacting mature miRNAs:194
Transcripts:ENSMUST00000032813, ENSMUST00000179893
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301572Sluc30_msusceptibility to lung cancer 30 (mouse)Not determined7243169636431844Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1357699Nhdlq6_mnon-HDL QTL 6 (mouse)Not determined7998886743988984Mouse
1558893Spir1_mStreptococcus pneumoniae infection resistance 1 (mouse)Not determined71030579844305936Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
1301041Prnr2_mprion resistance 2 (mouse)Not determined71872879439674033Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
7394747asp3_maudiogenic seizure prone 3 (mouse)Not determined72730579836842367Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse

Markers in Region
AI528790  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38729,003,373 - 29,003,512UniSTSGRCm38
MGSCv37729,788,392 - 29,788,531UniSTSGRCm37
Celera723,565,801 - 23,565,940UniSTS
Cytogenetic Map7B1UniSTS
Cytogenetic Map7A2-B3UniSTS
Whitehead/MRC_RH7401.22UniSTS
AW534727  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38729,069,088 - 29,069,629UniSTSGRCm38
MGSCv37729,854,107 - 29,854,648UniSTSGRCm37
Celera723,639,537 - 23,640,078UniSTS
Cytogenetic Map7A2-B3UniSTS
Ryr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A2-B3UniSTS
Ryr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A2-B3UniSTS
cM Map710.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006539689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC164564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC165142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ308737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ310365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ310366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY268935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U23754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X95655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000032813   ⟹   ENSMUSP00000032813
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,702,769 - 28,824,576 (-)Ensembl
GRCm38.p6 Ensembl729,003,344 - 29,125,151 (-)Ensembl
RefSeq Acc Id: ENSMUST00000179893   ⟹   ENSMUSP00000137123
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,702,769 - 28,824,576 (-)Ensembl
GRCm38.p6 Ensembl729,003,344 - 29,125,151 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207764
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,768,424 - 28,771,502 (-)Ensembl
GRCm38.p6 Ensembl729,068,999 - 29,072,077 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207783
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,813,608 - 28,824,604 (-)Ensembl
GRCm38.p6 Ensembl729,114,183 - 29,125,179 (-)Ensembl
RefSeq Acc Id: ENSMUST00000208010
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,744,621 - 28,746,939 (-)Ensembl
GRCm38.p6 Ensembl729,045,196 - 29,047,514 (-)Ensembl
RefSeq Acc Id: ENSMUST00000208318
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,721,524 - 28,746,108 (-)Ensembl
GRCm38.p6 Ensembl729,022,099 - 29,046,683 (-)Ensembl
RefSeq Acc Id: ENSMUST00000208922
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,822,053 - 28,824,577 (-)Ensembl
GRCm38.p6 Ensembl729,122,628 - 29,125,152 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214374   ⟹   ENSMUSP00000149042
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl728,702,769 - 28,824,440 (-)Ensembl
GRCm38.p6 Ensembl729,003,344 - 29,125,015 (-)Ensembl
RefSeq Acc Id: NM_009109   ⟹   NP_033135
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,702,765 - 28,824,576 (-)NCBI
GRCm38729,003,340 - 29,125,151 (-)NCBI
MGSCv37729,788,359 - 29,910,170 (-)RGD
Celera723,565,768 - 23,695,212 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006539689   ⟹   XP_006539752
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,702,765 - 28,824,599 (-)NCBI
GRCm38729,003,340 - 29,125,179 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152814   ⟹   XP_036008707
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,702,765 - 28,824,599 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152815   ⟹   XP_036008708
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,702,765 - 28,824,599 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152816   ⟹   XP_036008709
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,702,765 - 28,824,599 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152817   ⟹   XP_036008710
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,702,765 - 28,824,599 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152818   ⟹   XP_036008711
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,702,765 - 28,824,599 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036152819   ⟹   XP_036008712
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39728,702,765 - 28,824,599 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033135   ⟸   NM_009109
- UniProtKB: Q99JF9 (UniProtKB/Swiss-Prot),   E9PZQ0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006539752   ⟸   XM_006539689
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSMUSP00000032813   ⟸   ENSMUST00000032813
RefSeq Acc Id: ENSMUSP00000137123   ⟸   ENSMUST00000179893
RefSeq Acc Id: ENSMUSP00000149042   ⟸   ENSMUST00000214374
RefSeq Acc Id: XP_036008712   ⟸   XM_036152819
- Peptide Label: isoform X7
RefSeq Acc Id: XP_036008710   ⟸   XM_036152817
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036008708   ⟸   XM_036152815
- Peptide Label: isoform X2
RefSeq Acc Id: XP_036008711   ⟸   XM_036152818
- Peptide Label: isoform X6
RefSeq Acc Id: XP_036008709   ⟸   XM_036152816
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036008707   ⟸   XM_036152814
- Peptide Label: isoform X1
Protein Domains
B30.2/SPRY   EF-hand   MIR   RIH

Promoters
RGD ID:6892512
Promoter ID:EPDNEW_M9707
Type:multiple initiation site
Name:Ryr1_1
Description:Mus musculus ryanodine receptor 1, skeletal muscle , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38729,125,152 - 29,125,212EPDNEW
RGD ID:6841968
Promoter ID:MM_KWN:49695
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:NM_009109,   UC009GAR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36729,909,806 - 29,910,306 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99659 AgrOrtholog
Ensembl Genes ENSMUSG00000030592 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000032813 ENTREZGENE
  ENSMUSP00000032813.10 UniProtKB/TrEMBL
  ENSMUSP00000137123 ENTREZGENE
  ENSMUSP00000137123.2 UniProtKB/Swiss-Prot
  ENSMUSP00000149042 ENTREZGENE
  ENSMUSP00000149042.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032813 ENTREZGENE
  ENSMUST00000032813.10 UniProtKB/TrEMBL
  ENSMUST00000179893 ENTREZGENE
  ENSMUST00000179893.9 UniProtKB/Swiss-Prot
  ENSMUST00000214374 ENTREZGENE
  ENSMUST00000214374.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.490.160 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.120.920 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.80.10.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.20.350.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IP3 receptor type 1 binding core, RIH domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ins145_P3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryan_recept UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryanodine_IP3_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryanodine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryanrecept_TM4-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR/IP3R_RIH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY1_RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY2_RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY3_RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20190 UniProtKB/Swiss-Prot
MGD MGI:99659 ENTREZGENE
NCBI Gene 20190 ENTREZGENE
PANTHER B30.2/SPRY DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RYANODINE RECEPTOR 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ins145_P3_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RR_TM4-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RYDR_ITPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB RYR1 RGD
PhenoGen Ryr1 PhenoGen
PRINTS RYANODINER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPRY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF100909 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1L1SQG7_MOUSE UniProtKB/TrEMBL
  E9PZQ0 ENTREZGENE
  K3W4M2_MOUSE UniProtKB/TrEMBL
  P70272_MOUSE UniProtKB/TrEMBL
  Q8C4R0_MOUSE UniProtKB/TrEMBL
  Q99JE8_MOUSE UniProtKB/TrEMBL
  Q99JF9 ENTREZGENE
  RYR1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q60834 UniProtKB/Swiss-Prot
  Q61779 UniProtKB/Swiss-Prot
  Q61780 UniProtKB/Swiss-Prot
  Q62173 UniProtKB/Swiss-Prot
  Q62196 UniProtKB/Swiss-Prot
  Q62235 UniProtKB/Swiss-Prot
  Q78EJ6 UniProtKB/Swiss-Prot
  Q7TNG1 UniProtKB/Swiss-Prot
  Q80UQ5 UniProtKB/Swiss-Prot
  Q80X16 UniProtKB/Swiss-Prot
  Q99JF9 UniProtKB/Swiss-Prot