Lmo2 (LIM domain only 2) - Rat Genome Database

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Gene: Lmo2 (LIM domain only 2) Mus musculus
Analyze
Symbol: Lmo2
Name: LIM domain only 2
RGD ID: 1316094
MGI Page MGI
Description: Enables chromatin binding activity. Contributes to DNA binding activity. Involved in negative regulation of erythrocyte differentiation. Acts upstream of or within embryonic hemopoiesis and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human LMO2 (LIM domain only 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cysteine-rich protein TTG-2; LIM domain only protein 2; LIM only 2; LMO-2; Rbt; Rbtn; Rbtn-2; Rbtn2; Rhom; Rhom-2; rhombotin-2; T-cell translocation protein 2; Ttg2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392103,788,309 - 103,812,223 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2103,788,331 - 103,812,223 (+)EnsemblGRCm39 Ensembl
GRCm382103,957,903 - 103,981,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2103,957,986 - 103,981,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv372103,798,152 - 103,822,035 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362103,771,062 - 103,782,713 (+)NCBIMGSCv36mm8
Celera2105,204,167 - 105,227,999 (+)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (EXP)
butanal  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloroprene  (EXP)
cisplatin  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
dioxygen  (EXP)
diquat  (EXP)
dorsomorphin  (ISO)
endosulfan  (ISO)
flusilazole  (ISO)
furan  (ISO)
isotretinoin  (ISO)
lipopolysaccharide  (ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
O-methyleugenol  (ISO)
ozone  (EXP)
panobinostat  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pomalidomide  (ISO)
propanal  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal allantois morphology  (IAGP)
abnormal blood cell morphology  (IAGP)
abnormal bone marrow cell number  (IAGP)
abnormal bone marrow morphology  (IAGP)
abnormal cell death  (IAGP)
abnormal common myeloid progenitor cell morphology  (IAGP)
abnormal dorsal aorta morphology  (IAGP)
abnormal embryonic hematopoiesis  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal mast cell morphology  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal megakaryocyte progenitor cell morphology  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal spleen red pulp morphology  (IAGP)
abnormal spleen white pulp morphology  (IAGP)
absent visceral yolk sac blood islands  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased embryo size  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased erythroid progenitor cell number  (IAGP)
decreased granulocyte monocyte progenitor cell number  (IAGP)
decreased granulocyte number  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased hemoglobin content  (IAGP)
decreased megakaryocyte-erythroid progenitor cell number  (IAGP)
decreased monocyte cell number  (IAGP)
delayed embryo turning  (IAGP)
delayed somite formation  (IAGP)
distended pericardium  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged spleen  (IAGP)
increased hemolymphoid system tumor incidence  (IAGP)
increased leukemia incidence  (IAGP)
increased mean corpuscular volume  (IAGP)
increased red blood cell distribution width  (IAGP)
macrocytic anemia  (IAGP)
macrocytosis  (IAGP)
pale kidney  (IAGP)
pale liver  (IAGP)
pale yolk sac  (IAGP)
pallor  (IAGP)
premature death  (IAGP)
prenatal lethality  (IAGP)
short rostral-caudal axis  (IAGP)
small visceral yolk sac  (IAGP)
thrombocytopenia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Jak2 is essential for signaling through a variety of cytokine receptors. Parganas E, etal., Cell 1998 May 1;93(3):385-95.
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1507224   PMID:2034676   PMID:7568177   PMID:7579400   PMID:7624372   PMID:7830794   PMID:7970726   PMID:8033210   PMID:9001422   PMID:9028937   PMID:9116269   PMID:9204936  
PMID:9391090   PMID:9520463   PMID:9736723   PMID:9819382   PMID:9860983   PMID:10349636   PMID:10431247   PMID:10477673   PMID:10618416   PMID:10631184   PMID:11042159   PMID:11076861  
PMID:11165475   PMID:11466623   PMID:11751867   PMID:12477932   PMID:12619132   PMID:12727888   PMID:12781363   PMID:14645513   PMID:14681479   PMID:15295034   PMID:15489334   PMID:15761153  
PMID:15782199   PMID:15911088   PMID:15914564   PMID:15994290   PMID:16096649   PMID:16109169   PMID:16141072   PMID:16141073   PMID:16407974   PMID:16597514   PMID:16602821   PMID:17090656  
PMID:17108004   PMID:17535249   PMID:17605779   PMID:17878155   PMID:18184866   PMID:18213587   PMID:18287559   PMID:18347158   PMID:18438427   PMID:19011221   PMID:19171877   PMID:19323994  
PMID:19461887   PMID:19799863   PMID:19877281   PMID:19966810   PMID:20059953   PMID:20093438   PMID:20211142   PMID:20231428   PMID:20531244   PMID:20554972   PMID:20647008   PMID:20660741  
PMID:20861166   PMID:21057528   PMID:21267068   PMID:21427293   PMID:21670468   PMID:21862448   PMID:21873635   PMID:22058113   PMID:22222369   PMID:22628281   PMID:22936624   PMID:23112163  
PMID:23193182   PMID:23285212   PMID:23378057   PMID:23708655   PMID:23801765   PMID:23840778   PMID:23892628   PMID:23926305   PMID:24146773   PMID:24465765   PMID:24475213   PMID:24792354  
PMID:25283843   PMID:25694434   PMID:26764384   PMID:26862168   PMID:27118408   PMID:27256700   PMID:28065741   PMID:28973433   PMID:29141987   PMID:29778661   PMID:29880602   PMID:30700838  
PMID:34321664   PMID:34321999   PMID:34382935   PMID:35364055   PMID:35508511   PMID:36920307  


Genomics

Comparative Map Data
Lmo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392103,788,309 - 103,812,223 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2103,788,331 - 103,812,223 (+)EnsemblGRCm39 Ensembl
GRCm382103,957,903 - 103,981,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2103,957,986 - 103,981,878 (+)EnsemblGRCm38mm10GRCm38
MGSCv372103,798,152 - 103,822,035 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362103,771,062 - 103,782,713 (+)NCBIMGSCv36mm8
Celera2105,204,167 - 105,227,999 (+)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.46NCBI
LMO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381133,858,576 - 33,892,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1133,858,576 - 33,892,076 (-)EnsemblGRCh38hg38GRCh38
GRCh371133,880,122 - 33,913,623 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361133,836,698 - 33,870,412 (-)NCBINCBI36Build 36hg18NCBI36
Build 341133,836,700 - 33,870,412NCBI
Celera1134,027,627 - 34,061,421 (-)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1133,576,315 - 33,610,063 (-)NCBIHuRef
CHM1_11133,879,643 - 33,913,368 (-)NCBICHM1_1
T2T-CHM13v2.01133,995,616 - 34,029,225 (-)NCBIT2T-CHM13v2.0
Lmo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2390,355,234 - 90,377,970 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl390,365,883 - 90,377,953 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx393,848,260 - 93,870,995 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03102,447,339 - 102,470,072 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03100,277,857 - 100,300,590 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0393,909,156 - 93,931,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl393,909,156 - 93,931,871 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03100,549,307 - 100,572,039 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4389,356,199 - 89,367,641 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1389,252,944 - 89,263,314 (+)NCBI
Celera389,416,677 - 89,439,412 (+)NCBICelera
Cytogenetic Map3q32NCBI
Lmo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542212,354,845 - 12,362,470 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542212,354,865 - 12,362,026 (+)NCBIChiLan1.0ChiLan1.0
LMO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11136,082,565 - 36,115,729 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01133,830,370 - 33,863,960 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,712,099 - 33,720,729 (-)NCBIpanpan1.1PanPan1.1panPan2
LMO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1833,481,882 - 33,492,473 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01834,487,785 - 34,497,780 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11834,045,610 - 34,056,746 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01833,639,096 - 33,649,686 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01834,274,467 - 34,285,055 (+)NCBIUU_Cfam_GSD_1.0
Lmo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494730,982,272 - 30,992,326 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365334,107,067 - 4,117,222 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365334,107,073 - 4,117,121 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LMO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl227,044,763 - 27,055,453 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1227,033,924 - 27,055,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2229,401,270 - 29,422,801 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LMO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1131,382,437 - 31,416,256 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl131,404,872 - 31,416,883 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038128,481,321 - 128,514,918 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lmo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476713,245,984 - 13,257,440 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476713,245,783 - 13,257,322 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lmo2
519 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2734
Count of miRNA genes:596
Interacting mature miRNAs:728
Transcripts:ENSMUST00000111139, ENSMUST00000111140, ENSMUST00000111143, ENSMUST00000123437, ENSMUST00000133210, ENSMUST00000138815, ENSMUST00000156813, ENSMUST00000163256, ENSMUST00000170926
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286095716120095823Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286095716120095823Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287440643121440778Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288015003122015170Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88143423122143570Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291089974125090104Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292778465126778607Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
4141448Mpaps1_mmicrophthalmia anophthalmia susceptibility 1 (mouse)Not determined97028557112115196Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse

Markers in Region
PMC309712P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382103,976,012 - 103,976,195UniSTSGRCm38
MGSCv372103,816,169 - 103,816,352UniSTSGRCm37
Celera2105,222,132 - 105,222,315UniSTS
Cytogenetic Map2E2UniSTS
cM Map260.0UniSTS
GDB:197859  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382103,976,072 - 103,976,223UniSTSGRCm38
MGSCv372103,816,229 - 103,816,380UniSTSGRCm37
Celera2105,222,192 - 105,222,343UniSTS
Cytogenetic Map2E2UniSTS
cM Map260.0UniSTS
Lmo2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map260.0UniSTS
cM Map260.0UniSTS
cM Map260.0UniSTS
Lmo2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map260.0UniSTS
Lmo2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS
cM Map260.0UniSTS
Lmo2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2E2UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001142335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001142336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001142337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK013416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV361906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB864414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX523983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX640578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX226855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX228914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX234489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M64359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M64360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W76814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000111139   ⟹   ENSMUSP00000106769
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,800,589 - 103,812,184 (+)Ensembl
GRCm38.p6 Ensembl2103,970,244 - 103,981,839 (+)Ensembl
RefSeq Acc Id: ENSMUST00000111140   ⟹   ENSMUSP00000106770
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,800,568 - 103,812,219 (+)Ensembl
GRCm38.p6 Ensembl2103,970,223 - 103,981,874 (+)Ensembl
RefSeq Acc Id: ENSMUST00000111143   ⟹   ENSMUSP00000106773
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,800,474 - 103,812,200 (+)Ensembl
GRCm38.p6 Ensembl2103,970,129 - 103,981,855 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123437   ⟹   ENSMUSP00000117703
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,799,873 - 103,811,437 (+)Ensembl
GRCm38.p6 Ensembl2103,969,528 - 103,981,092 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,801,524 - 103,811,261 (+)Ensembl
GRCm38.p6 Ensembl2103,971,179 - 103,980,916 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138815   ⟹   ENSMUSP00000121927
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,800,486 - 103,806,487 (+)Ensembl
GRCm38.p6 Ensembl2103,970,141 - 103,976,142 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156813   ⟹   ENSMUSP00000122369
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,788,331 - 103,811,395 (+)Ensembl
GRCm38.p6 Ensembl2103,957,986 - 103,981,050 (+)Ensembl
RefSeq Acc Id: ENSMUST00000170926   ⟹   ENSMUSP00000128317
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2103,788,340 - 103,812,223 (+)Ensembl
GRCm38.p6 Ensembl2103,957,995 - 103,981,878 (+)Ensembl
RefSeq Acc Id: NM_001142335   ⟹   NP_001135807
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,800,495 - 103,812,223 (+)NCBI
GRCm382103,970,287 - 103,981,878 (+)NCBI
MGSCv372103,798,152 - 103,822,035 (+)RGD
Celera2105,204,167 - 105,227,999 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001142336   ⟹   NP_001135808
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,799,902 - 103,812,223 (+)NCBI
GRCm382103,969,557 - 103,981,878 (+)NCBI
MGSCv372103,798,152 - 103,822,035 (+)RGD
Celera2105,204,167 - 105,227,999 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001142337   ⟹   NP_001135809
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,788,309 - 103,812,223 (+)NCBI
GRCm382103,957,995 - 103,981,878 (+)NCBI
MGSCv372103,798,152 - 103,822,035 (+)RGD
Celera2105,204,167 - 105,227,999 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001420375   ⟹   NP_001407304
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,800,495 - 103,807,874 (+)NCBI
RefSeq Acc Id: NM_001420376   ⟹   NP_001407305
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,788,309 - 103,812,223 (+)NCBI
RefSeq Acc Id: NM_001420377   ⟹   NP_001407306
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,788,309 - 103,812,223 (+)NCBI
RefSeq Acc Id: NM_001420378   ⟹   NP_001407307
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,788,309 - 103,812,223 (+)NCBI
RefSeq Acc Id: NM_001420379   ⟹   NP_001407308
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,799,902 - 103,812,223 (+)NCBI
RefSeq Acc Id: NM_001420380   ⟹   NP_001407309
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,788,309 - 103,807,874 (+)NCBI
RefSeq Acc Id: NM_001420381   ⟹   NP_001407310
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,799,902 - 103,807,874 (+)NCBI
RefSeq Acc Id: NM_001420382   ⟹   NP_001407311
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,799,902 - 103,807,874 (+)NCBI
RefSeq Acc Id: NM_008505   ⟹   NP_032531
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,800,495 - 103,812,223 (+)NCBI
GRCm382103,970,287 - 103,981,878 (+)NCBI
MGSCv372103,798,152 - 103,822,035 (+)RGD
Celera2105,204,167 - 105,227,999 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006498820   ⟹   XP_006498883
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392103,800,088 - 103,812,223 (+)NCBI
GRCm382103,969,743 - 103,981,878 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032531   ⟸   NM_008505
- Peptide Label: isoform 1
- UniProtKB: A2BHP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001135809   ⟸   NM_001142337
- Peptide Label: isoform 3
- UniProtKB: P25801 (UniProtKB/Swiss-Prot),   Q544Z2 (UniProtKB/TrEMBL),   A2BHP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001135808   ⟸   NM_001142336
- Peptide Label: isoform 3
- UniProtKB: P25801 (UniProtKB/Swiss-Prot),   Q544Z2 (UniProtKB/TrEMBL),   A2BHP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001135807   ⟸   NM_001142335
- Peptide Label: isoform 2
- UniProtKB: A2BHP5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498883   ⟸   XM_006498820
- Peptide Label: isoform X1
- UniProtKB: P25801 (UniProtKB/Swiss-Prot),   Q544Z2 (UniProtKB/TrEMBL),   A2BHP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000106769   ⟸   ENSMUST00000111139
RefSeq Acc Id: ENSMUSP00000106773   ⟸   ENSMUST00000111143
RefSeq Acc Id: ENSMUSP00000106770   ⟸   ENSMUST00000111140
RefSeq Acc Id: ENSMUSP00000121927   ⟸   ENSMUST00000138815
RefSeq Acc Id: ENSMUSP00000128317   ⟸   ENSMUST00000170926
RefSeq Acc Id: ENSMUSP00000117703   ⟸   ENSMUST00000123437
RefSeq Acc Id: ENSMUSP00000122369   ⟸   ENSMUST00000156813
RefSeq Acc Id: NP_001407305   ⟸   NM_001420376
- Peptide Label: isoform 3
- UniProtKB: P25801 (UniProtKB/Swiss-Prot),   A2BHP2 (UniProtKB/TrEMBL),   Q544Z2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001407306   ⟸   NM_001420377
- Peptide Label: isoform 3
- UniProtKB: P25801 (UniProtKB/Swiss-Prot),   A2BHP2 (UniProtKB/TrEMBL),   Q544Z2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001407307   ⟸   NM_001420378
- Peptide Label: isoform 3
- UniProtKB: P25801 (UniProtKB/Swiss-Prot),   A2BHP2 (UniProtKB/TrEMBL),   Q544Z2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001407309   ⟸   NM_001420380
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001407308   ⟸   NM_001420379
- Peptide Label: isoform 3
- UniProtKB: P25801 (UniProtKB/Swiss-Prot),   A2BHP2 (UniProtKB/TrEMBL),   Q544Z2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001407310   ⟸   NM_001420381
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001407311   ⟸   NM_001420382
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001407304   ⟸   NM_001420375
- Peptide Label: isoform 4
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P25801-F1-model_v2 AlphaFold P25801 1-158 view protein structure

Promoters
RGD ID:6831721
Promoter ID:MM_KWN:30810
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung
Transcripts:ENSMUST00000040619,   ENSMUST00000111139,   ENSMUST00000111143,   OTTMUST00000035398,   OTTMUST00000035403,   OTTMUST00000035407
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362103,809,681 - 103,811,257 (+)MPROMDB
RGD ID:6878086
Promoter ID:EPDNEW_M2494
Type:initiation region
Name:Lmo2_1
Description:Mus musculus LIM domain only 2 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2495  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382103,969,557 - 103,969,617EPDNEW
RGD ID:6878088
Promoter ID:EPDNEW_M2495
Type:initiation region
Name:Lmo2_2
Description:Mus musculus LIM domain only 2 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2494  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382103,970,231 - 103,970,291EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102811 AgrOrtholog
Ensembl Genes ENSMUSG00000032698 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000111139.3 UniProtKB/TrEMBL
  ENSMUST00000111140 ENTREZGENE
  ENSMUST00000111140.3 UniProtKB/TrEMBL
  ENSMUST00000111143 ENTREZGENE
  ENSMUST00000111143.8 UniProtKB/TrEMBL
  ENSMUST00000123437 ENTREZGENE
  ENSMUST00000123437.8 UniProtKB/Swiss-Prot
  ENSMUST00000138815.2 UniProtKB/TrEMBL
  ENSMUST00000156813.8 UniProtKB/TrEMBL
  ENSMUST00000170926 ENTREZGENE
  ENSMUST00000170926.8 UniProtKB/Swiss-Prot
Gene3D-CATH Cysteine Rich Protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Znf_LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16909 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:102811 ENTREZGENE
NCBI Gene 16909 ENTREZGENE
PANTHER LD11652P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHOMBOTIN-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lmo2 PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2BHP1_MOUSE UniProtKB/TrEMBL
  A2BHP2 ENTREZGENE, UniProtKB/TrEMBL
  A2BHP3 ENTREZGENE, UniProtKB/TrEMBL
  A2BHP4_MOUSE UniProtKB/TrEMBL
  A2BHP5 ENTREZGENE, UniProtKB/TrEMBL
  P25801 ENTREZGENE
  Q544Z2 ENTREZGENE, UniProtKB/TrEMBL
  RBTN2_MOUSE UniProtKB/Swiss-Prot