Olig2 (oligodendrocyte transcription factor 2) - Rat Genome Database

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Gene: Olig2 (oligodendrocyte transcription factor 2) Mus musculus
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Symbol: Olig2
Name: oligodendrocyte transcription factor 2
RGD ID: 1316089
MGI Page MGI
Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; HMG box domain binding activity; and identical protein binding activity. Acts upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; nervous system development; and positive regulation of oligodendrocyte differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; epidermis; future brain; genitourinary system; and sensory organ. Orthologous to human OLIG2 (oligodendrocyte transcription factor 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI604895; Bhlhb; Bhlhb1; bHLHe1; bHLHe19; Olg; Olg-2; Oligo2; RK1; RK17
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391691,016,745 - 91,025,567 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1691,022,345 - 91,025,565 (+)EnsemblGRCm39 Ensembl
GRCm381691,225,550 - 91,228,677 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1691,225,457 - 91,228,677 (+)EnsemblGRCm38mm10GRCm38
MGSCv371691,225,795 - 91,228,922 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361691,114,409 - 91,117,536 (+)NCBIMGSCv36mm8
Celera1692,308,914 - 92,312,041 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1652.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal brain development  (IAGP)
abnormal brain morphology  (IAGP)
abnormal brainstem morphology  (IAGP)
abnormal breathing pattern  (IAGP)
abnormal cell differentiation  (IAGP)
abnormal CNS synaptic transmission  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal dendrite morphology  (IAGP)
abnormal dorsal root ganglion morphology  (IAGP)
abnormal excitatory postsynaptic potential  (IAGP)
abnormal glial cell physiology  (IAGP)
abnormal hindbrain development  (IAGP)
abnormal miniature endplate potential  (IAGP)
abnormal muscle morphology  (IAGP)
abnormal myelination  (IAGP)
abnormal nervous system development  (IAGP)
abnormal neuromuscular synapse morphology  (IAGP)
abnormal neuronal migration  (IAGP)
abnormal oligodendrocyte morphology  (IAGP)
abnormal oligodendrocyte physiology  (IAGP)
abnormal optic nerve morphology  (IAGP)
abnormal PNS synaptic transmission  (IAGP)
abnormal posture  (IAGP)
abnormal proprioceptive neuron morphology  (IAGP)
abnormal reflex  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal sensory neuron morphology  (IAGP)
abnormal spinal cord lateral motor column morphology  (IAGP)
abnormal spinal cord medial motor column morphology  (IAGP)
abnormal spinal cord morphology  (IAGP)
abnormal spinal cord motor column morphology  (IAGP)
abnormal spinal cord ventral horn morphology  (IAGP)
abnormal synaptic bouton morphology  (IAGP)
abnormal synaptic transmission  (IAGP)
abnormal ventral interneuron 1 morphology  (IAGP)
abnormal ventral interneuron 2 morphology  (IAGP)
absent oligodendrocytes  (IAGP)
aphagia  (IAGP)
ataxia  (IAGP)
decreased body weight  (IAGP)
decreased epididymal fat pad weight  (IAGP)
decreased fetal size  (IAGP)
decreased grip strength  (IAGP)
decreased motor neuron number  (IAGP)
decreased oligodendrocyte number  (IAGP)
decreased oligodendrocyte progenitor number  (IAGP)
decreased skeletal muscle fiber number  (IAGP)
decreased survivor rate  (IAGP)
dysmyelination  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged lateral ventricles  (IAGP)
hypotonia  (IAGP)
impaired coordination  (IAGP)
impaired spatial learning  (IAGP)
increased brain tumor incidence  (IAGP)
increased brain weight  (IAGP)
increased glioma incidence  (IAGP)
increased medulloblastoma incidence  (IAGP)
increased oligodendrocyte number  (IAGP)
increased skeletal muscle fiber size  (IAGP)
kyphosis  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
limb grasping  (IAGP)
motor neuron degeneration  (IAGP)
muscle spasm  (IAGP)
muscle weakness  (IAGP)
muscular atrophy  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no spontaneous movement  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
seizures  (IAGP)
skeletal muscle fiber degeneration  (IAGP)
tremors  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. A gene expression map of human chromosome 21 orthologues in the mouse. Gitton Y, etal., Nature 2002 Dec 5;420(6915):586-90.
2. Neurotoxocarosis alters myelin protein gene transcription and expression. Heuer L, etal., Parasitol Res. 2015 Jun;114(6):2175-86. doi: 10.1007/s00436-015-4407-1. Epub 2015 Mar 17.
3. Effects of Olig2-overexpressing neural stem cells and myelin basic protein-activated T cells on recovery from spinal cord injury. Hu JG, etal., Neurotherapeutics. 2012 Apr;9(2):422-45. doi: 10.1007/s13311-011-0090-9.
4. Gene Expression Profiling of Breast Cancer Brain Metastasis. Lee JY, etal., Sci Rep. 2016 Jun 24;6:28623. doi: 10.1038/srep28623.
5. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Lu QR, etal., Cell 2002 Apr 5;109(1):75-86.
6. Demyelination contributes to depression comorbidity in a rat model of chronic epilepsy via dysregulation of Olig2/LINGO-1 and disturbance of calcium homeostasis. Ma T, etal., Exp Neurol. 2019 Nov;321:113034. doi: 10.1016/j.expneurol.2019.113034. Epub 2019 Aug 12.
7. Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis. Masliah E, etal., J Neuroimmunol. 2004 Dec;157(1-2):163-75. doi: 10.1016/j.jneuroim.2004.08.026.
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. MGD IEA MGD IEA
10. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11. Therapeutic Potential of Pien Tze Huang on Experimental Autoimmune Encephalomyelitis Rat. Qiu X, etal., J Immunol Res. 2018 Feb 27;2018:2952471. doi: 10.1155/2018/2952471. eCollection 2018.
12. Human chromosome 21 gene expression atlas in the mouse. Reymond A, etal., Nature 2002 Dec 5;420(6915):582-6.
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Local injection of Lenti-Olig2 at lesion site promotes functional recovery of spinal cord injury in rats. Tan BT, etal., CNS Neurosci Ther. 2017 Jun;23(6):475-487. doi: 10.1111/cns.12694. Epub 2017 Apr 27.
16. [Effect of Yishen Daluo Decoction on the expression of PLP, Olig1, and Olig2 in mice with experimental autoimmune encephalomyelitis]. Zhu WH, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 May;34(5):562-5.
Additional References at PubMed
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PMID:32129762   PMID:32135084   PMID:32142668   PMID:32179479   PMID:32187534   PMID:32234482   PMID:32238932   PMID:32266943   PMID:32278722   PMID:32294450   PMID:32366272   PMID:32386572  
PMID:32449185   PMID:32450295   PMID:32515730   PMID:32521266   PMID:32541003   PMID:32568216   PMID:32579270   PMID:32702291   PMID:32708917   PMID:32737167   PMID:32758357   PMID:32765228  
PMID:32817053   PMID:32913108   PMID:32937136   PMID:32943498   PMID:32976762   PMID:33060130   PMID:33086038   PMID:33165593   PMID:33187539   PMID:33203872   PMID:33277484   PMID:33462220  
PMID:33510480   PMID:33547135   PMID:33570491   PMID:33574458   PMID:33591268   PMID:33602870   PMID:33618751   PMID:33674582   PMID:33739968   PMID:33775695   PMID:33787491   PMID:33848959  
PMID:33869166   PMID:33887203   PMID:33899734   PMID:33938018   PMID:34132778   PMID:34222248   PMID:34287339   PMID:34296073   PMID:34321999   PMID:34336815   PMID:34339499   PMID:34400844  
PMID:34428430   PMID:34429415   PMID:34486668   PMID:34536353   PMID:34587162   PMID:34610310   PMID:34614421   PMID:34615523   PMID:34630045   PMID:34655526   PMID:34749773   PMID:34752747  
PMID:34963132   PMID:34974536   PMID:34994686   PMID:35022234   PMID:35089129   PMID:35132995   PMID:35177643   PMID:35187673   PMID:35231638   PMID:35301318   PMID:35315772   PMID:35353806  
PMID:35377797   PMID:35399523   PMID:35524725   PMID:35535852   PMID:35695185   PMID:35736214   PMID:35815610   PMID:35853870   PMID:35906071   PMID:36067211   PMID:36154712   PMID:36198499  
PMID:36265906   PMID:36280666   PMID:36323680   PMID:36370145   PMID:36402907   PMID:36476860   PMID:36512397   PMID:36547371   PMID:36549270   PMID:36550293   PMID:36634201   PMID:36669111  
PMID:36737666   PMID:36915679   PMID:37017184   PMID:37054704   PMID:37075114   PMID:37099424   PMID:37300483   PMID:37307456   PMID:37364986   PMID:37371026   PMID:37389991   PMID:37390294  
PMID:37407594   PMID:37414952   PMID:37416774   PMID:37463107   PMID:37463454   PMID:37543947   PMID:37553426   PMID:37566909   PMID:37590144   PMID:37684687   PMID:37738575   PMID:37756583  
PMID:37858465   PMID:37869988   PMID:37897724   PMID:37906993   PMID:37924811   PMID:37943875   PMID:38025769   PMID:38062045   PMID:38079449   PMID:38086370   PMID:38091994   PMID:38101413  
PMID:38171360   PMID:38227267   PMID:38269113   PMID:38366596   PMID:38383496   PMID:38419656   PMID:38429579   PMID:38433925   PMID:38487272   PMID:38507412   PMID:38546197   PMID:38696583  
PMID:38713624   PMID:38942786  


Genomics

Comparative Map Data
Olig2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391691,016,745 - 91,025,567 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1691,022,345 - 91,025,565 (+)EnsemblGRCm39 Ensembl
GRCm381691,225,550 - 91,228,677 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1691,225,457 - 91,228,677 (+)EnsemblGRCm38mm10GRCm38
MGSCv371691,225,795 - 91,228,922 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361691,114,409 - 91,117,536 (+)NCBIMGSCv36mm8
Celera1692,308,914 - 92,312,041 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1652.6NCBI
OLIG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382133,025,935 - 33,029,185 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2133,025,935 - 33,029,196 (+)EnsemblGRCh38hg38GRCh38
GRCh372134,398,243 - 34,401,493 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362133,320,109 - 33,323,370 (+)NCBINCBI36Build 36hg18NCBI36
Build 342133,320,162 - 33,323,371NCBI
Celera2119,583,840 - 19,587,101 (+)NCBICelera
Cytogenetic Map21q22.11NCBI
HuRef2119,809,438 - 19,812,730 (+)NCBIHuRef
CHM1_12133,960,322 - 33,963,610 (+)NCBICHM1_1
T2T-CHM13v2.02131,394,108 - 31,397,358 (+)NCBIT2T-CHM13v2.0
Olig2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81143,961,585 - 43,964,961 (+)NCBIGRCr8
mRatBN7.21130,475,510 - 30,478,886 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1130,475,398 - 30,480,152 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1139,162,510 - 39,165,873 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01131,833,948 - 31,837,317 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01131,008,354 - 31,011,714 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01131,389,514 - 31,392,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1131,389,514 - 31,392,890 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01134,998,542 - 35,001,918 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,205,416 - 31,208,792 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11131,244,022 - 31,245,269 (+)NCBI
Celera1130,143,763 - 30,147,131 (+)NCBICelera
Cytogenetic Map11q11NCBI
Olig2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540732,433,849 - 32,434,923 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540732,432,888 - 32,436,209 (+)NCBIChiLan1.0ChiLan1.0
OLIG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22229,138,290 - 29,141,729 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12123,998,222 - 24,001,643 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02119,387,860 - 19,391,291 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12132,766,039 - 32,769,408 (+)NCBIpanpan1.1PanPan1.1panPan2
OLIG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13127,674,112 - 27,677,521 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3127,674,107 - 27,676,822 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3127,667,931 - 27,670,007 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03127,878,129 - 27,880,215 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3127,878,117 - 27,880,829 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13127,745,936 - 27,748,017 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03127,755,719 - 27,757,790 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03128,259,002 - 28,261,083 (+)NCBIUU_Cfam_GSD_1.0
Olig2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497128,219,922 - 28,222,625 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365009,245,880 - 9,247,756 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365009,244,595 - 9,247,756 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OLIG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13196,599,822 - 196,600,793 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113196,596,838 - 196,602,197 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213206,661,824 - 206,663,897 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OLIG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1259,151,151 - 59,161,253 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl259,152,487 - 59,153,458 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660711,690,456 - 1,693,867 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Olig2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474521,270,965 - 21,272,932 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474521,270,804 - 21,274,225 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Olig2
238 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:441
Count of miRNA genes:305
Interacting mature miRNAs:349
Transcripts:ENSMUST00000035608
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302194Pgia10_mproteoglycan induced arthritis 10 (mouse)Not determined166860072298008968Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163544664392573008Mouse
1300928Etia_methanol induced activation (mouse)Not determined166331390797314016Mouse
1558740Bpq9_mblood pressure QTL 9 (mouse)Not determined166332733697327472Mouse
1301125Sluc27_msusceptibility to lung cancer 27 (mouse)Not determined166160864495608764Mouse
4141113Tgq28_mtriglyceride QTL 28 (mouse)Not determined6298664696986646Mouse
4142262Lmr18_mleishmaniasis resistance 18 (mouse)Not determined166912761198008968Mouse
1301032Tauph_mtau phosphorylation (mouse)Not determined166907613298008968Mouse
11049573Lmr18b_mleishmaniasis resistance 18b (mouse)166912761198008968Mouse
1301598Renf2_mrenal failure 2 (mouse)Not determined167038025298008968Mouse
11049574Lmr18a_mleishmaniasis resistance 18a (mouse)166912761198008968Mouse
11522753Cocia19_mcocaine-induced activity, QTL 19 (mouse)166925448298008968Mouse

Markers in Region
AI604895  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381691,228,376 - 91,228,507UniSTSGRCm38
MGSCv371691,228,621 - 91,228,752UniSTSGRCm37
Celera1692,311,740 - 92,311,871UniSTS
Cytogenetic Map16C3.3UniSTS
Whitehead/MRC_RH16965.09UniSTS
Olig2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381691,226,668 - 91,226,918UniSTSGRCm38
MGSCv371691,226,913 - 91,227,163UniSTSGRCm37
Celera1692,310,032 - 92,310,282UniSTS
Cytogenetic Map16C3.3UniSTS
cM Map1663.0UniSTS
REN83531  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381691,226,870 - 91,227,127UniSTSGRCm38
MGSCv371691,227,115 - 91,227,372UniSTSGRCm37
Celera1692,310,234 - 92,310,491UniSTS
Cytogenetic Map16C3.3UniSTS
REN83532  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381691,227,109 - 91,227,369UniSTSGRCm38
MGSCv371691,227,354 - 91,227,614UniSTSGRCm37
Celera1692,310,473 - 92,310,733UniSTS
Cytogenetic Map16C3.3UniSTS
Olig2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381691,227,938 - 91,228,440UniSTSGRCm38
MGSCv371691,228,183 - 91,228,685UniSTSGRCm37
Celera1692,311,302 - 92,311,804UniSTS
Cytogenetic Map16C3.3UniSTS
Olig2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C3.3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000035608   ⟹   ENSMUSP00000036797
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1691,022,345 - 91,025,565 (+)Ensembl
GRCm38.p6 Ensembl1691,225,457 - 91,228,677 (+)Ensembl
RefSeq Acc Id: NM_016967   ⟹   NP_058663
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391691,022,438 - 91,025,565 (+)NCBI
GRCm381691,225,550 - 91,228,677 (+)ENTREZGENE
MGSCv371691,225,795 - 91,228,922 (+)RGD
Celera1692,308,914 - 92,312,041 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036160000   ⟹   XP_036015893
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391691,016,745 - 91,025,567 (+)NCBI
Sequence:
RefSeq Acc Id: NP_058663   ⟸   NM_016967
- UniProtKB: Q9JKN4 (UniProtKB/Swiss-Prot),   Q9EQW6 (UniProtKB/Swiss-Prot),   Q542S0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000036797   ⟸   ENSMUST00000035608
RefSeq Acc Id: XP_036015893   ⟸   XM_036160000
- Peptide Label: isoform X1
- UniProtKB: Q9EQW6 (UniProtKB/Swiss-Prot),   Q9JKN4 (UniProtKB/Swiss-Prot),   Q542S0 (UniProtKB/TrEMBL)
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EQW6-F1-model_v2 AlphaFold Q9EQW6 1-323 view protein structure

Promoters
RGD ID:13674426
Promoter ID:EPDNEW_M21362
Type:multiple initiation site
Name:Olig2_1
Description:Mus musculus oligodendrocyte transcription factor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381691,225,572 - 91,225,632EPDNEW
RGD ID:6827316
Promoter ID:MM_KWN:21685
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell
Transcripts:NM_016967
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361691,225,674 - 91,226,174 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1355331 AgrOrtholog
Ensembl Genes ENSMUSG00000039830 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000035608 ENTREZGENE
  ENSMUST00000035608.10 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bHLH_transcription_factors UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Olig2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:50913 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1355331 ENTREZGENE
NCBI Gene 50913 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR19290:SF32 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Olig2 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt OLIG2_MOUSE UniProtKB/Swiss-Prot
  Q542S0 ENTREZGENE, UniProtKB/TrEMBL
  Q9EQW6 ENTREZGENE
  Q9JKN4 ENTREZGENE
UniProt Secondary Q9JKN4 UniProtKB/Swiss-Prot