Nadk2 (NAD kinase 2, mitochondrial) - Rat Genome Database

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Gene: Nadk2 (NAD kinase 2, mitochondrial) Mus musculus
Analyze
Symbol: Nadk2
Name: NAD kinase 2, mitochondrial
RGD ID: 1315634
MGI Page MGI
Description: Enables NAD+ kinase activity. Involved in NADP biosynthetic process. Located in mitochondrion. Is active in mitochondrial matrix. Is expressed in retina. Orthologous to human NADK2 (NAD kinase 2, mitochondrial).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110020G09Rik; 4933430B08Rik; hypothetical protein LOC68646; mitochondrial NAD kinase; MNA; MNADK; NAD kinase domain-containing protein 1; NAD kinase domain-containing protein 1, mitochondrial; Nadk; Nadkd1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39159,071,340 - 9,110,584 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl159,071,340 - 9,110,979 (+)EnsemblGRCm39 Ensembl
GRCm38159,071,260 - 9,110,496 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,071,260 - 9,110,891 (+)EnsemblGRCm38mm10GRCm38
MGSCv37159,001,009 - 9,040,244 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36158,998,111 - 9,038,170 (+)NCBIMGSCv36mm8
Celera158,884,697 - 8,927,605 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map153.82NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP)
entinostat  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
flutamide  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
glafenine  (ISO)
GSK-J4  (ISO)
inulin  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosomorpholine  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenobarbital  (EXP)
potassium chromate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrial matrix  (IMP)
mitochondrion  (HDA,IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. MNADK, a Long-Awaited Human Mitochondrion-Localized NAD Kinase. Zhang R J Cell Physiol. 2015 Aug;230(8):1697-701. doi: 10.1002/jcp.24926.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:14651853   PMID:16141072   PMID:16141073  
PMID:18799693   PMID:21267068   PMID:21677750   PMID:21873635   PMID:23341629   PMID:23616928   PMID:28923496   PMID:29539633   PMID:29997285   PMID:30418981   PMID:30550785   PMID:30973865  
PMID:35796562   PMID:35944895   PMID:36631013   PMID:38355793  


Genomics

Comparative Map Data
Nadk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39159,071,340 - 9,110,584 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl159,071,340 - 9,110,979 (+)EnsemblGRCm39 Ensembl
GRCm38159,071,260 - 9,110,496 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,071,260 - 9,110,891 (+)EnsemblGRCm38mm10GRCm38
MGSCv37159,001,009 - 9,040,244 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36158,998,111 - 9,038,170 (+)NCBIMGSCv36mm8
Celera158,884,697 - 8,927,605 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map153.82NCBI
NADK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38536,192,589 - 36,242,279 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl536,192,589 - 36,242,279 (-)EnsemblGRCh38hg38GRCh38
GRCh37536,192,691 - 36,242,381 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36536,228,451 - 36,278,015 (-)NCBINCBI36Build 36hg18NCBI36
Celera536,078,373 - 36,127,931 (-)NCBICelera
Cytogenetic Map5p13.2NCBI
HuRef536,143,686 - 36,193,895 (-)NCBIHuRef
CHM1_1536,195,428 - 36,245,010 (-)NCBICHM1_1
T2T-CHM13v2.0536,440,876 - 36,490,588 (-)NCBIT2T-CHM13v2.0
Nadk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8259,844,854 - 59,886,989 (+)NCBIGRCr8
mRatBN7.2258,117,674 - 58,159,815 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl258,117,674 - 58,159,808 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx265,215,434 - 65,257,679 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0263,327,755 - 63,369,942 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0258,329,066 - 58,371,261 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0258,462,588 - 58,504,735 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl258,462,588 - 58,504,728 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0277,550,016 - 77,592,163 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4258,725,461 - 58,767,746 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1258,653,693 - 58,694,420 (+)NCBI
Celera253,725,937 - 53,768,584 (+)NCBICelera
Cytogenetic Map2q16NCBI
Nadk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542621,004,785 - 21,049,050 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542621,002,849 - 21,049,187 (-)NCBIChiLan1.0ChiLan1.0
NADK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2474,087,676 - 74,136,980 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1572,241,308 - 72,290,612 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0574,121,313 - 74,170,774 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1579,402,924 - 79,452,194 (+)NCBIpanpan1.1PanPan1.1panPan2
Nadk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213225,738,877 - 225,786,016 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365185,586,077 - 5,631,018 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365185,585,911 - 5,632,961 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NADK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1621,506,769 - 21,557,274 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11621,507,422 - 21,557,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21622,523,734 - 22,574,171 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NADK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1435,043,211 - 35,088,725 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl435,042,814 - 35,076,288 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607125,374,466 - 25,419,928 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nadk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475918,775,798 - 18,811,811 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475918,775,783 - 18,813,409 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nadk2
1295 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1506
Count of miRNA genes:341
Interacting mature miRNAs:394
Transcripts:ENSMUST00000067760, ENSMUST00000100789, ENSMUST00000100790
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
1301136Pgia8_mproteoglycan induced arthritis 8 (mouse)Not determined15324016724388176Mouse
11252136Modvl4_mmodifier of vacuolated lens (mouse)15562049439620614Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
1357459Nhdlq7_mnon-HDL QTL 7 (mouse)Not determined15120489829Mouse
1300953Bdt5_mbone density traits 5 (mouse)Not determined15120489829Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
1301023Sluc24_msusceptibility to lung cancer 24 (mouse)Not determined15120489829Mouse
1301662Faq8_mfluctuating asymmetry QTL 8 (mouse)Not determined15120489829Mouse
26884439Sklq11_mskull length QTL 11, 10 week (mouse)15812948447663396Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
4141358Ath22_matherosclerosis 22 (mouse)Not determined346465237464652Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
26884429Zlq6_mzygomatic length QTL 6, 10 week (mouse)15682948144963396Mouse
27226759Feml17_mfemur length 17, 10 week (mouse)15762948155263396Mouse
27095940Ulnl8_mulna length 8, 10 week (mouse)15722948155263396Mouse
4141541Tglq3_mtriglyceride QTL 3 (mouse)Not determined15120489829Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15612948172471849Mouse
27226755Feml22_mfemur length 22, 16 week (mouse)15762948159271849Mouse
11062069Bpq31_mblood pressure QTL 31 (mouse)15126273195Mouse
1300594Eae2_msusceptibility to experimental allergic encephalomyelitis 2 (mouse)Not determined15131218736Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
26884409Bzwq16_mbi-zygomatic width QTL 16, 16 week (mouse)15612948138000244Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15612948171471849Mouse
5491193Mobq4_mmultigenic obesity QTL 4 (mouse)Not determined15120489829Mouse
27095922Pglq11_mpelvic girdle length QTL 11, 10 week (mouse)15812948438763395Mouse
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15347438971197538Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
4141446Ffaq4_mfree fatty acid QTL 4 (mouse)Not determined127101390Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15612948168271849Mouse
1302121Cliff_mcliff drop aversion (mouse)Not determined15120489829Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15612948150763396Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001040395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001085410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC139209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC161575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK016988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW537715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE692075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF460794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG143421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY545448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000067760   ⟹   ENSMUSP00000068318
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl159,071,260 - 9,110,487 (+)Ensembl
Ensembl Acc Id: ENSMUST00000100789   ⟹   ENSMUSP00000098353
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl159,071,260 - 9,110,487 (+)Ensembl
Ensembl Acc Id: ENSMUST00000100790   ⟹   ENSMUSP00000098354
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl159,071,260 - 9,110,487 (+)Ensembl
Ensembl Acc Id: ENSMUST00000186069
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,103,076 - 9,106,858 (+)Ensembl
GRCm38.p6 Ensembl159,102,988 - 9,106,770 (+)Ensembl
Ensembl Acc Id: ENSMUST00000188194   ⟹   ENSMUSP00000140212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,100,244 - 9,107,266 (+)Ensembl
GRCm38.p6 Ensembl159,100,156 - 9,107,178 (+)Ensembl
Ensembl Acc Id: ENSMUST00000189211
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,085,880 - 9,106,925 (+)Ensembl
GRCm38.p6 Ensembl159,085,800 - 9,106,837 (+)Ensembl
Ensembl Acc Id: ENSMUST00000189437
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,071,761 - 9,109,948 (+)Ensembl
GRCm38.p6 Ensembl159,071,681 - 9,109,860 (+)Ensembl
Ensembl Acc Id: ENSMUST00000190591
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,071,340 - 9,110,979 (+)Ensembl
GRCm38.p6 Ensembl159,071,260 - 9,110,891 (+)Ensembl
Ensembl Acc Id: ENSMUST00000190874
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,071,767 - 9,107,260 (+)Ensembl
GRCm38.p6 Ensembl159,071,687 - 9,107,172 (+)Ensembl
Ensembl Acc Id: ENSMUST00000227682
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,071,655 - 9,092,955 (+)Ensembl
GRCm38.p6 Ensembl159,071,575 - 9,092,866 (+)Ensembl
Ensembl Acc Id: ENSMUST00000227928
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,094,736 - 9,103,126 (+)Ensembl
GRCm38.p6 Ensembl159,094,647 - 9,103,038 (+)Ensembl
Ensembl Acc Id: ENSMUST00000228397
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,075,357 - 9,091,340 (+)Ensembl
GRCm38.p6 Ensembl159,075,277 - 9,091,260 (+)Ensembl
Ensembl Acc Id: ENSMUST00000228453
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl159,092,298 - 9,108,404 (+)Ensembl
GRCm38.p6 Ensembl159,092,209 - 9,108,316 (+)Ensembl
RefSeq Acc Id: NM_001040395   ⟹   NP_001035485
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39159,071,340 - 9,110,584 (+)NCBI
GRCm38159,071,260 - 9,110,496 (+)NCBI
MGSCv37159,001,009 - 9,040,244 (+)RGD
Celera158,884,697 - 8,927,614 (+)NCBI
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001085410   ⟹   NP_001078879
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39159,071,340 - 9,110,584 (+)NCBI
GRCm38159,071,260 - 9,110,496 (+)NCBI
MGSCv37159,001,009 - 9,040,244 (+)RGD
Celera158,884,697 - 8,927,614 (+)NCBI
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001286253   ⟹   NP_001273182
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39159,071,340 - 9,107,266 (+)NCBI
GRCm38159,071,260 - 9,107,178 (+)NCBI
Celera158,884,697 - 8,927,614 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001286255   ⟹   NP_001273184
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39159,071,340 - 9,110,584 (+)NCBI
GRCm38159,071,260 - 9,110,496 (+)NCBI
Celera158,884,697 - 8,927,614 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001035485   ⟸   NM_001040395
- Peptide Label: isoform 2
- UniProtKB: Q14BL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001078879   ⟸   NM_001085410
- Peptide Label: isoform 1
- UniProtKB: Q3UEY1 (UniProtKB/Swiss-Prot),   Q3TRP5 (UniProtKB/Swiss-Prot),   Q9CTE4 (UniProtKB/Swiss-Prot),   Q8C5H8 (UniProtKB/Swiss-Prot),   Q14BL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273184   ⟸   NM_001286255
- Peptide Label: isoform 4
- UniProtKB: A0A7N9VS49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273182   ⟸   NM_001286253
- Peptide Label: isoform 3
- UniProtKB: A0A7P0A156 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000068318   ⟸   ENSMUST00000067760
Ensembl Acc Id: ENSMUSP00000140212   ⟸   ENSMUST00000188194
Ensembl Acc Id: ENSMUSP00000098354   ⟸   ENSMUST00000100790
Ensembl Acc Id: ENSMUSP00000098353   ⟸   ENSMUST00000100789

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C5H8-F1-model_v2 AlphaFold Q8C5H8 1-452 view protein structure

Promoters
RGD ID:6825568
Promoter ID:MM_KWN:18012
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:ENSMUST00000100789,   NM_001040395,   NM_001085410,   UC007VFC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36159,000,631 - 9,001,282 (+)MPROMDB
RGD ID:8683380
Promoter ID:EPDNEW_M19720
Type:initiation region
Name:Nadk2_1
Description:Mus musculus NAD kinase 2, mitochondrial , transcript variant4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19721  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38159,071,268 - 9,071,328EPDNEW
RGD ID:8683396
Promoter ID:EPDNEW_M19721
Type:initiation region
Name:Nadk2_2
Description:Mus musculus NAD kinase 2, mitochondrial , transcript variant4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19720  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38159,071,460 - 9,071,520EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915896 AgrOrtholog
Ensembl Genes ENSMUSG00000022253 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000189437 ENTREZGENE
  ENSMUST00000190591 ENTREZGENE
  ENSMUST00000190591.10 UniProtKB/Swiss-Prot
  ENSMUST00000190874 ENTREZGENE
Gene3D-CATH Probable inorganic polyphosphate/atp-NAD kinase, domain 1 UniProtKB/Swiss-Prot
  Probable inorganic polyphosphate/atp-NAD kinase, domain 2 UniProtKB/Swiss-Prot
InterPro ATP-NAD_kinase_N UniProtKB/Swiss-Prot
  ATP-NAD_kinase_PpnK-typ_C UniProtKB/Swiss-Prot
  NAD/diacylglycerol_kinase_sf UniProtKB/Swiss-Prot
  NADK UniProtKB/Swiss-Prot
  NADK2_mit UniProtKB/Swiss-Prot
KEGG Report mmu:68646 UniProtKB/Swiss-Prot
MGD MGI:1915896 ENTREZGENE
NCBI Gene 68646 ENTREZGENE
PANTHER NAD KINASE 2, MITOCHONDRIAL UniProtKB/Swiss-Prot
  PTHR13158 UniProtKB/Swiss-Prot
Pfam NAD_kinase UniProtKB/Swiss-Prot
PhenoGen Nadk2 PhenoGen
PIRSF Kin_ATP-NAD_euk UniProtKB/Swiss-Prot
Superfamily-SCOP SSF111331 UniProtKB/Swiss-Prot
UniProt A0A087WQI8_MOUSE UniProtKB/TrEMBL
  A0A7N9VS49 ENTREZGENE, UniProtKB/TrEMBL
  A0A7N9VSY3_MOUSE UniProtKB/TrEMBL
  A0A7N9VT10_MOUSE UniProtKB/TrEMBL
  A0A7P0A156 ENTREZGENE, UniProtKB/TrEMBL
  NAKD2_MOUSE UniProtKB/Swiss-Prot
  Q14BL1 ENTREZGENE, UniProtKB/TrEMBL
  Q3TRP5 ENTREZGENE
  Q3UEY1 ENTREZGENE
  Q8C5H8 ENTREZGENE
  Q9CTE4 ENTREZGENE
  Q9CUB4_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TRP5 UniProtKB/Swiss-Prot
  Q3UEY1 UniProtKB/Swiss-Prot
  Q9CTE4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-06 Nadk2  NAD kinase 2, mitochondrial  Nadkd1  NAD kinase domain containing 1  Symbol and/or name change 5135510 APPROVED
2012-06-19 Nadkd1  NAD kinase domain containing 1  1110020G09Rik  RIKEN cDNA 1110020G09 gene  Symbol and/or name change 5135510 APPROVED