Lrig1 (leucine-rich repeats and immunoglobulin-like domains 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Lrig1 (leucine-rich repeats and immunoglobulin-like domains 1) Mus musculus
Analyze
Symbol: Lrig1
Name: leucine-rich repeats and immunoglobulin-like domains 1
RGD ID: 1315603
MGI Page MGI
Description: Acts upstream of or within several processes, including innervation; otolith morphogenesis; and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; heart; integumental system; and sensory organ. Orthologous to human LRIG1 (leucine rich repeats and immunoglobulin like domains 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D6Bwg0781e; Im; Img; integral membrane glycoprotein; leucine-rich repeats and immunoglobulin-like domains protein 1; LIG; LIG-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39694,581,510 - 94,677,205 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl694,581,510 - 94,677,139 (-)EnsemblGRCm39 Ensembl
GRCm38694,604,529 - 94,700,298 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl694,604,529 - 94,700,158 (-)EnsemblGRCm38mm10GRCm38
MGSCv37694,554,523 - 94,650,139 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36694,569,992 - 94,665,608 (-)NCBIMGSCv36mm8
Celera696,504,989 - 96,600,773 (-)NCBICelera
Cytogenetic Map6D2NCBI
cM Map643.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
amphetamine  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
clothianidin  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (EXP,ISO)
cytarabine  (ISO)
dexamethasone  (EXP,ISO)
Dibutyl phosphate  (ISO)
dioxygen  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
fenthion  (EXP)
fluoranthene  (EXP)
folic acid  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
indometacin  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
Monobutylphthalate  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
okadaic acid  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
progesterone  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
SM-164  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal auditory brainstem response  (IAGP)
abnormal auditory brainstem response waveform shape  (IAGP)
abnormal behavior  (IEA)
abnormal crypts of Lieberkuhn morphology  (IAGP)
abnormal dermis papillary layer morphology  (IEA)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal facial morphology  (IAGP)
abnormal hair cycle  (IAGP)
abnormal hair follicle matrix region morphology  (IEA)
abnormal hair shaft morphology  (IEA)
abnormal hair shedding  (IAGP)
abnormal inner ear development  (IAGP)
abnormal keratinocyte differentiation  (IAGP)
abnormal lateral semicircular canal morphology  (IAGP)
abnormal otolith organ morphology  (IAGP)
abnormal posterior semicircular canal morphology  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal skin adnexa morphology  (IAGP)
abnormal skin condition  (IAGP)
abnormal skin morphology  (IAGP)
abnormal tail morphology  (IEA)
alopecia  (IAGP)
circling  (IAGP)
decreased body length  (IEA)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral density  (IAGP)
decreased circulating alanine transaminase level  (IAGP)
decreased circulating alkaline phosphatase level  (IAGP)
decreased circulating aspartate transaminase level  (IAGP)
decreased hair follicle number  (IEA)
decreased posterior semicircular canal size  (IAGP)
decreased total body fat amount  (IAGP)
disheveled coat  (IAGP)
distorted hair follicle pattern  (IAGP)
epidermal hyperplasia  (IAGP)
fusion of vertebral arches  (IAGP)
hair follicle degeneration  (IEA)
hyperkeratosis  (IAGP)
increased intestinal adenoma incidence  (IAGP)
increased keratinocyte proliferation  (IAGP)
increased or absent distortion product otoacoustic emission threshold  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
microphthalmia  (IAGP)
no abnormal phenotype detected  (IAGP)
parakeratosis  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
psoriasis  (IAGP)
scaly skin  (IAGP)
thick epidermis  (IAGP)
thick tail  (IAGP)
vertebral fusion  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis. Barbieri AM, etal., Proc Natl Acad Sci U S A 1999 Sep 14;96(19):10729-34.
2. Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Neidhardt L, etal., Mech Dev 2000 Nov;98(1-2):77-94.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8798419   PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11414704   PMID:12067728   PMID:12477932   PMID:14610273   PMID:14681479   PMID:14691545  
PMID:15345710   PMID:16141072   PMID:16141073   PMID:18171921   PMID:18480165   PMID:18848646   PMID:18922900   PMID:19004851   PMID:19427292   PMID:20223988   PMID:21677750   PMID:21873635  
PMID:22008794   PMID:22227295   PMID:22388892   PMID:22464327   PMID:23208928   PMID:23271346   PMID:23487314   PMID:23558895   PMID:23954751   PMID:24086156   PMID:24198274   PMID:24316976  
PMID:24336287   PMID:24652767   PMID:24721909   PMID:24735878   PMID:24833705   PMID:25340873   PMID:25358790   PMID:25480918   PMID:25794708   PMID:25826454   PMID:25842978   PMID:25921371  
PMID:26015543   PMID:26073039   PMID:26590425   PMID:26651291   PMID:26753643   PMID:26837596   PMID:26930384   PMID:26935556   PMID:27287810   PMID:28094771   PMID:28099467   PMID:28475038  
PMID:28494873   PMID:28504705   PMID:28814482   PMID:29153838   PMID:29249464   PMID:29391393   PMID:29395868   PMID:29643507   PMID:30033638   PMID:30109253   PMID:30248341   PMID:30323305  
PMID:30415840   PMID:30472156   PMID:30550785   PMID:30578323   PMID:30585163   PMID:30689807   PMID:30886049   PMID:30956133   PMID:30973865   PMID:31059499   PMID:31481792   PMID:31488717  
PMID:31564613   PMID:31690663   PMID:31796338   PMID:31813825   PMID:32183906   PMID:32245826   PMID:32259481   PMID:32325033   PMID:32515350   PMID:32730753   PMID:32828819   PMID:32944951  
PMID:33053360   PMID:33759564   PMID:33972529   PMID:33984283   PMID:33989815   PMID:34124060   PMID:34338291   PMID:34582748   PMID:34939928   PMID:35132078   PMID:35294885   PMID:35364055  
PMID:35508126   PMID:35815643   PMID:36631891   PMID:36899019   PMID:37081165   PMID:37142655   PMID:37166989   PMID:37652012   PMID:37666819   PMID:37715952   PMID:37873577   PMID:38355793  
PMID:38758807   PMID:38941190   PMID:39250533   PMID:39361422   PMID:39587709   PMID:39955307  


Genomics

Comparative Map Data
Lrig1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39694,581,510 - 94,677,205 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl694,581,510 - 94,677,139 (-)EnsemblGRCm39 Ensembl
GRCm38694,604,529 - 94,700,298 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl694,604,529 - 94,700,158 (-)EnsemblGRCm38mm10GRCm38
MGSCv37694,554,523 - 94,650,139 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36694,569,992 - 94,665,608 (-)NCBIMGSCv36mm8
Celera696,504,989 - 96,600,773 (-)NCBICelera
Cytogenetic Map6D2NCBI
cM Map643.15NCBI
LRIG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38366,378,797 - 66,501,121 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl366,378,797 - 66,501,263 (-)EnsemblGRCh38hg38GRCh38
GRCh37366,429,221 - 66,551,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36366,511,911 - 66,633,535 (-)NCBINCBI36Build 36hg18NCBI36
Build 34366,511,911 - 66,633,535NCBI
Celera366,375,063 - 66,496,661 (-)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef366,446,562 - 66,568,141 (-)NCBIHuRef
CHM1_1366,380,462 - 66,502,073 (-)NCBICHM1_1
T2T-CHM13v2.0366,423,367 - 66,545,661 (-)NCBIT2T-CHM13v2.0
Lrig1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84128,687,723 - 128,788,219 (-)NCBIGRCr8
mRatBN7.24127,130,899 - 127,230,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4127,130,898 - 127,231,513 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.04126,615,998 - 126,717,434 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4126,617,244 - 126,644,895 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04191,129,832 - 191,231,014 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44128,919,630 - 129,082,488 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14129,164,514 - 129,327,329 (-)NCBI
Celera4116,039,860 - 116,139,967 (-)NCBICelera
Cytogenetic Map4q34NCBI
Lrig1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542121,108,611 - 21,218,016 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542121,108,609 - 21,219,293 (+)NCBIChiLan1.0ChiLan1.0
LRIG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2266,291,853 - 66,413,885 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1366,296,639 - 66,418,810 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0366,271,849 - 66,394,056 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1367,642,858 - 67,764,513 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl367,644,289 - 67,765,194 (-)Ensemblpanpan1.1panPan2
LRIG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12024,907,904 - 25,033,841 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2024,890,191 - 25,032,647 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2024,866,159 - 24,944,926 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02024,948,748 - 25,059,572 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2024,948,172 - 25,058,308 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12024,645,797 - 24,756,555 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02024,992,924 - 25,103,683 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02025,052,534 - 25,163,376 (+)NCBIUU_Cfam_GSD_1.0
Lrig1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118161,718,879 - 161,849,167 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936637108,471 - 237,390 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936637108,433 - 238,723 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRIG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1347,909,011 - 48,027,384 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11347,909,002 - 48,027,396 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21352,651,474 - 52,770,251 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRIG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12227,401,399 - 27,573,395 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2227,402,851 - 27,528,331 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041139,284,707 - 139,411,562 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrig1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624773713,520 - 849,999 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624773712,193 - 850,086 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lrig1
4856 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1186
Count of miRNA genes:579
Interacting mature miRNAs:679
Transcripts:ENSMUST00000032105, ENSMUST00000101126, ENSMUST00000124165, ENSMUST00000141014, ENSMUST00000150811
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
11532719Sluc45_msusceptibility to lung cancer 45 (mouse)69258428798235894Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671958006105958152Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671958006105958152Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67797698396976961Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
12792979Fbmd2_mfemoral bone mineral density 2, females only (mouse)675026989115026943Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671552042105552160Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675424566104480516Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined688982366122982564Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684099474118099474Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687480321121480516Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675584287109584431Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686783787113521563Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670402880104403016Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670402880104403016Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676440930110441074Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66346172197461888Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675693484109693678Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690772571124772807Mouse
4141578Obrq1_mobesity resistance QTL 1 (mouse)Not determined92584287111981699Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666690851100691013Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670402880104403016Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681476981102176961Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678606487121092347Mouse

Markers in Region
AW557176  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38694,604,072 - 94,604,180UniSTSGRCm38
MGSCv37694,554,066 - 94,554,174UniSTSGRCm37
Celera696,504,532 - 96,504,640UniSTS
Cytogenetic Map6D3UniSTS
Cytogenetic Map6D2UniSTS
cM Map639.0UniSTS
Whitehead/MRC_RH6976.33UniSTS
RH125079  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38694,604,428 - 94,604,536UniSTSGRCm38
MGSCv37694,554,422 - 94,554,530UniSTSGRCm37
Celera696,504,888 - 96,504,996UniSTS
Cytogenetic Map6D3UniSTS
Cytogenetic Map6D2UniSTS
cM Map639.0UniSTS
Lrig1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38694,605,760 - 94,607,314UniSTSGRCm38
MGSCv37694,555,754 - 94,557,308UniSTSGRCm37
Celera696,506,250 - 96,507,737UniSTS
Cytogenetic Map6D2UniSTS
cM Map639.0UniSTS
D5Bwg0834e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38694,604,371 - 94,604,537UniSTSGRCm38
MGSCv37694,554,365 - 94,554,531UniSTSGRCm37
Celera696,504,831 - 96,504,997UniSTS
Cytogenetic Map6D2UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map6D3UniSTS
cM Map568.0UniSTS
cM Map639.0UniSTS
Lrig1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D2UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001355269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036165882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC122272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC155330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF465831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN699905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D78572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000032105   ⟹   ENSMUSP00000032105
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl694,581,515 - 94,677,126 (-)Ensembl
GRCm38.p6 Ensembl694,604,534 - 94,700,145 (-)Ensembl
Ensembl Acc Id: ENSMUST00000101126   ⟹   ENSMUSP00000098686
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl694,581,517 - 94,677,118 (-)Ensembl
GRCm38.p6 Ensembl694,604,536 - 94,700,137 (-)Ensembl
Ensembl Acc Id: ENSMUST00000124165
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl694,605,056 - 94,655,846 (-)Ensembl
GRCm38.p6 Ensembl694,628,075 - 94,678,865 (-)Ensembl
Ensembl Acc Id: ENSMUST00000141014
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl694,602,015 - 94,657,611 (-)Ensembl
GRCm38.p6 Ensembl694,625,034 - 94,680,630 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150811
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl694,603,431 - 94,632,506 (-)Ensembl
GRCm38.p6 Ensembl694,626,450 - 94,655,525 (-)Ensembl
Ensembl Acc Id: ENSMUST00000203876
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl694,581,661 - 94,582,374 (-)Ensembl
GRCm38.p6 Ensembl694,604,680 - 94,605,393 (-)Ensembl
Ensembl Acc Id: ENSMUST00000204645   ⟹   ENSMUSP00000144963
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl694,581,510 - 94,677,139 (-)Ensembl
GRCm38.p6 Ensembl694,604,529 - 94,700,158 (-)Ensembl
RefSeq Acc Id: NM_001355269   ⟹   NP_001342198
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,677,149 (-)NCBI
GRCm38694,604,529 - 94,700,145 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001410069   ⟹   NP_001396998
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,658,671 (-)NCBI
RefSeq Acc Id: NM_001410070   ⟹   NP_001396999
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,657,626 (-)NCBI
RefSeq Acc Id: NM_008377   ⟹   NP_032403
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,677,149 (-)NCBI
GRCm38694,604,529 - 94,700,145 (-)NCBI
MGSCv37694,554,523 - 94,650,139 (-)RGD
Celera696,504,989 - 96,600,773 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_176936
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,677,149 (-)NCBI
RefSeq Acc Id: NR_176937
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,677,149 (-)NCBI
RefSeq Acc Id: XM_030255196   ⟹   XP_030111056
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,677,205 (-)NCBI
GRCm38694,604,529 - 94,700,200 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255197   ⟹   XP_030111057
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,607,609 (-)NCBI
GRCm38694,604,529 - 94,630,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030255198   ⟹   XP_030111058
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,616,837 (-)NCBI
GRCm38694,604,529 - 94,639,856 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036165882   ⟹   XP_036021775
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39694,581,510 - 94,612,054 (-)NCBI
Sequence:
RefSeq Acc Id: NP_032403   ⟸   NM_008377
- Peptide Label: isoform 1 precursor
- UniProtKB: E9QL89 (UniProtKB/Swiss-Prot),   P70193 (UniProtKB/Swiss-Prot),   B7ZP45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030111056   ⟸   XM_030255196
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001342198   ⟸   NM_001355269
- Peptide Label: isoform 2 precursor
- UniProtKB: B7ZP45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030111058   ⟸   XM_030255198
- Peptide Label: isoform X2
RefSeq Acc Id: XP_030111057   ⟸   XM_030255197
- Peptide Label: isoform X2
Ensembl Acc Id: ENSMUSP00000032105   ⟸   ENSMUST00000032105
Ensembl Acc Id: ENSMUSP00000144963   ⟸   ENSMUST00000204645
Ensembl Acc Id: ENSMUSP00000098686   ⟸   ENSMUST00000101126
RefSeq Acc Id: XP_036021775   ⟸   XM_036165882
- Peptide Label: isoform X1
- UniProtKB: B7ZP45 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001396998   ⟸   NM_001410069
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001396999   ⟸   NM_001410070
- Peptide Label: isoform 3
Protein Domains
Ig-like   Ig-like C2-type   LRRCT   LRRNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70193-F1-model_v2 AlphaFold P70193 1-1091 view protein structure

Promoters
RGD ID:6839579
Promoter ID:MM_KWN:46974
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4
Transcripts:OTTMUST00000060277
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36694,605,166 - 94,606,477 (-)MPROMDB
RGD ID:6839581
Promoter ID:MM_KWN:46975
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4
Transcripts:OTTMUST00000060279
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36694,628,456 - 94,629,857 (-)MPROMDB
RGD ID:6839580
Promoter ID:MM_KWN:46976
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Kidney
Transcripts:OTTMUST00000060278
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36694,630,386 - 94,631,607 (-)MPROMDB
RGD ID:6839578
Promoter ID:MM_KWN:46977
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000032105,   NM_008377
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36694,649,821 - 94,651,027 (-)MPROMDB
RGD ID:6890496
Promoter ID:EPDNEW_M8699
Type:multiple initiation site
Name:Lrig1_1
Description:Mus musculus leucine-rich repeats and immunoglobulin-like domains1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38694,700,164 - 94,700,224EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107935 AgrOrtholog
Ensembl Genes ENSMUSG00000030029 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000032105.11 UniProtKB/Swiss-Prot
  ENSMUST00000101126 ENTREZGENE
  ENSMUST00000101126.3 UniProtKB/Swiss-Prot
  ENSMUST00000204645.3 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.80.10.10 UniProtKB/Swiss-Prot
InterPro Cys-rich_flank_reg_C UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Leu-rich_rpt UniProtKB/Swiss-Prot
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot
  LRFN UniProtKB/Swiss-Prot
  LRR_dom_sf UniProtKB/Swiss-Prot
  LRRNT UniProtKB/Swiss-Prot
KEGG Report mmu:16206 UniProtKB/Swiss-Prot
MGD MGI:107935 ENTREZGENE
NCBI Gene 16206 ENTREZGENE
PANTHER INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT ISOFORM X1 UniProtKB/Swiss-Prot
  SYNAPTIC ADHESION-LIKE MOLECULE SALM UniProtKB/Swiss-Prot
Pfam I-set UniProtKB/Swiss-Prot
  Ig_3 UniProtKB/Swiss-Prot
  LRR_8 UniProtKB/Swiss-Prot
  LRRCT UniProtKB/Swiss-Prot
  LRRNT UniProtKB/Swiss-Prot
PhenoGen Lrig1 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
  LRR UniProtKB/Swiss-Prot
SMART IGc2 UniProtKB/Swiss-Prot
  LRR_SD22 UniProtKB/Swiss-Prot
  LRR_TYP UniProtKB/Swiss-Prot
  LRRCT UniProtKB/Swiss-Prot
  LRRNT UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot
  SSF48726 UniProtKB/Swiss-Prot
UniProt B7ZP45 ENTREZGENE, UniProtKB/TrEMBL
  E9QL89 ENTREZGENE
  LRIG1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary E9QL89 UniProtKB/Swiss-Prot