Ash1l (ASH1 like histone lysine methyltransferase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ash1l (ASH1 like histone lysine methyltransferase) Mus musculus
Analyze
Symbol: Ash1l
Name: ASH1 like histone lysine methyltransferase
RGD ID: 1314919
MGI Page MGI
Description: Enables histone H3K4 methyltransferase activity and histone H3K9 methyltransferase activity. Acts upstream of or within several processes, including decidualization; tarsal gland development; and uterine gland development. Predicted to be located in Golgi apparatus and nucleus. Predicted to be active in nucleoplasm. Is expressed in cerebral cortex; early conceptus; hindlimb muscle; oocyte; and ureter. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 52. Orthologous to human ASH1L (ASH1 like histone lysine methyltransferase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 8030453L17Rik; absent small and homeotic disks protein 1 homolog; absent, small, or homeotic 1-like; absent, small, or homeotic discs 1; Ash1; ash1 (absent, small, or homeotic)-like; ash1 (absent, small, or homeotic)-like (Drosophila); ASH1-like protein; chromatin remodeling factor; E430018P19Rik; histone-lysine N-methyltransferase ASH1L; Kmt2h; probable histone-lysine N-methyltransferase ASH1L
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39388,857,721 - 88,986,682 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl388,857,929 - 88,986,682 (+)EnsemblGRCm39 Ensembl
GRCm38388,950,414 - 89,079,375 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,950,622 - 89,079,375 (+)EnsemblGRCm38mm10GRCm38
MGSCv37388,769,734 - 88,883,297 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36389,051,739 - 89,165,302 (+)NCBIMGSCv36mm8
Celera389,004,378 - 89,118,066 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cauda epididymis morphology  (IAGP)
abnormal coat appearance  (IEA)
abnormal cornea epithelium morphology  (IAGP)
abnormal decidualization  (IAGP)
abnormal epididymis morphology  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal postimplantation uterine environment  (IAGP)
abnormal sperm number  (IAGP)
abnormal sternum morphology  (IAGP)
abnormal uterus morphology  (IAGP)
abnormal vas deferens morphology  (IAGP)
absent Meibomian glands  (IAGP)
asymmetric sternocostal joints  (IAGP)
blepharitis  (IAGP)
decreased abdominal adipose tissue amount  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased endometrial gland number  (IAGP)
decreased sebaceous gland number  (IAGP)
decreased survivor rate  (IAGP)
female infertility  (IAGP)
glomerulonephritis  (IAGP)
impaired pupillary reflex  (IEA)
increased autoantibody level  (IAGP)
increased basophil cell number  (IEA)
increased circulating interleukin-6 level  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased eosinophil cell number  (IEA)
increased fasting circulating glucose level  (IEA)
increased grip strength  (IEA)
increased heart weight  (IEA)
increased IgA level  (IAGP)
increased IgG1 level  (IAGP)
increased IgG2a level  (IAGP)
increased IgG2b level  (IAGP)
increased IgM level  (IAGP)
increased interleukin-6 secretion  (IAGP)
increased rib number  (IAGP)
increased susceptibility to autoimmune disorder  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to bacterial infection induced morbidity/mortality  (IAGP)
increased susceptibility to endotoxin shock  (IAGP)
increased susceptibility to induced arthritis  (IAGP)
increased tumor necrosis factor secretion  (IAGP)
postnatal growth retardation  (IAGP)
preweaning lethality, complete penetrance  (IEA)
pulmonary hyperemia  (IAGP)
reduced male fertility  (IAGP)
small uterus  (IAGP)
thin endometrium  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12477932   PMID:14610273   PMID:14681479   PMID:15489334   PMID:15618518   PMID:15780994   PMID:16096065  
PMID:16141072   PMID:16141073   PMID:16751776   PMID:17544230   PMID:17981149   PMID:18022353   PMID:18287559   PMID:18799693   PMID:20211142   PMID:20412781   PMID:21267068   PMID:21873635  
PMID:22939622   PMID:24012418   PMID:24019522   PMID:24619213   PMID:25866973   PMID:26333994   PMID:26549848   PMID:27229316   PMID:28374742   PMID:28598443   PMID:29724719   PMID:30186101  
PMID:30487570   PMID:31673123   PMID:32325033   PMID:32398261   PMID:34145365   PMID:34321999   PMID:34782621   PMID:35081333   PMID:35449559   PMID:36094439   PMID:37766518   PMID:38355793  
PMID:38431690  


Genomics

Comparative Map Data
Ash1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39388,857,721 - 88,986,682 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl388,857,929 - 88,986,682 (+)EnsemblGRCm39 Ensembl
GRCm38388,950,414 - 89,079,375 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl388,950,622 - 89,079,375 (+)EnsemblGRCm38mm10GRCm38
MGSCv37388,769,734 - 88,883,297 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36389,051,739 - 89,165,302 (+)NCBIMGSCv36mm8
Celera389,004,378 - 89,118,066 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.01NCBI
ASH1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381155,335,268 - 155,563,202 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1155,335,268 - 155,563,162 (-)EnsemblGRCh38hg38GRCh38
GRCh371155,305,059 - 155,532,594 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361153,571,676 - 153,798,948 (-)NCBINCBI36Build 36hg18NCBI36
Build 341152,119,816 - 152,345,226NCBI
Celera1128,378,194 - 128,605,465 (-)NCBICelera
Cytogenetic Map1q22NCBI
HuRef1126,666,854 - 126,894,253 (-)NCBIHuRef
CHM1_11156,700,472 - 156,927,715 (-)NCBICHM1_1
T2T-CHM13v2.01154,473,797 - 154,701,755 (-)NCBIT2T-CHM13v2.0
Ash1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82176,644,393 - 176,780,848 (+)NCBIGRCr8
mRatBN7.22174,346,267 - 174,483,057 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2174,346,150 - 174,483,055 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2181,493,612 - 181,629,480 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02179,515,973 - 179,651,840 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,115,988 - 174,251,798 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02188,252,592 - 188,389,251 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2188,253,220 - 188,389,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02207,652,622 - 207,801,285 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,015,194 - 181,151,274 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12180,980,929 - 181,099,849 (+)NCBI
Celera2168,291,369 - 168,427,302 (+)NCBICelera
Cytogenetic Map2q34NCBI
Ash1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,778,905 - 1,923,104 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555451,778,905 - 1,950,656 (-)NCBIChiLan1.0ChiLan1.0
ASH1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2194,281,503 - 94,509,171 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,013,794 - 94,240,479 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01130,679,868 - 130,906,918 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11134,284,366 - 134,622,782 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1134,286,761 - 134,468,722 (-)Ensemblpanpan1.1panPan2
ASH1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,046,262 - 42,227,737 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,046,569 - 42,225,456 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,537,531 - 41,718,668 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0741,915,693 - 42,096,922 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl741,916,185 - 42,095,973 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1741,695,692 - 41,876,805 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,749,423 - 41,930,582 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,033,639 - 42,214,584 (+)NCBIUU_Cfam_GSD_1.0
Ash1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,791,003 - 25,966,730 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,820,142 - 4,997,112 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,821,384 - 4,997,112 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASH1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,297,616 - 94,484,990 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,297,532 - 94,484,994 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,140,687 - 103,276,650 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASH1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1208,290,606 - 8,499,991 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl208,322,504 - 8,500,129 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660387,616,915 - 7,837,352 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ash1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624885961,880 - 1,136,731 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624885961,880 - 1,136,990 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ash1l
2966 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:855
Count of miRNA genes:489
Interacting mature miRNAs:564
Transcripts:ENSMUST00000090933
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369625509100655290Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
10043981Cia5a_mcollagen induced arthritis QTL 5a (mouse)Not determined38717045489140094Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse

Markers in Region
D3Mit282  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38389,014,012 - 89,014,133UniSTSGRCm38
MGSCv37388,817,934 - 88,818,055UniSTSGRCm37
Celera389,052,390 - 89,052,507UniSTS
Cytogenetic Map3F1UniSTS
cM Map341.0UniSTS
Whitehead Genetic330.6UniSTS
Whitehead/MRC_RH3908.82UniSTS
UniSTS:234728  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38389,030,094 - 89,030,316UniSTSGRCm38
MGSCv37388,834,016 - 88,834,238UniSTSGRCm37
Celera389,068,455 - 89,068,677UniSTS
Cytogenetic Map3F1UniSTS
UniSTS:225099  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38388,973,720 - 88,973,910UniSTSGRCm38
MGSCv37388,777,642 - 88,777,832UniSTSGRCm37
Celera389,012,299 - 89,012,489UniSTS
Cytogenetic Map3F1UniSTS
AL033792  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38388,985,289 - 88,985,428UniSTSGRCm38
MGSCv37388,789,211 - 88,789,350UniSTSGRCm37
Celera389,023,849 - 89,023,988UniSTS
Cytogenetic Map3F1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_138679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006501142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001783666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB221625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB221626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB221627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC127377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC140468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02172195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF167627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK627544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ550002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000090933   ⟹   ENSMUSP00000088451
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl388,873,119 - 88,986,680 (+)Ensembl
GRCm38.p6 Ensembl388,965,812 - 89,079,373 (+)Ensembl
Ensembl Acc Id: ENSMUST00000186583   ⟹   ENSMUSP00000140251
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl388,857,929 - 88,986,682 (+)Ensembl
GRCm38.p6 Ensembl388,950,622 - 89,079,375 (+)Ensembl
Ensembl Acc Id: ENSMUST00000189824
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl388,960,109 - 88,963,087 (+)Ensembl
GRCm38.p6 Ensembl389,052,802 - 89,055,780 (+)Ensembl
Ensembl Acc Id: ENSMUST00000198846
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl388,930,490 - 88,935,575 (+)Ensembl
GRCm38.p6 Ensembl389,023,183 - 89,028,268 (+)Ensembl
RefSeq Acc Id: NM_138679   ⟹   NP_619620
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,873,119 - 88,986,682 (+)NCBI
GRCm38388,965,812 - 89,079,375 (+)NCBI
MGSCv37388,769,734 - 88,883,297 (+)RGD
Celera389,004,378 - 89,118,066 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006501141   ⟹   XP_006501204
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,857,900 - 88,986,682 (+)NCBI
GRCm38388,950,597 - 89,079,375 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006501142   ⟹   XP_006501205
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,857,721 - 88,986,682 (+)NCBI
GRCm38388,950,414 - 89,079,375 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017319499   ⟹   XP_017174988
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,857,900 - 88,939,022 (+)NCBI
GRCm38388,950,597 - 89,033,321 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017319502   ⟹   XP_017174991
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,891,767 - 88,986,682 (+)NCBI
GRCm38388,985,210 - 89,079,375 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030252468   ⟹   XP_030108328
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,857,872 - 88,986,682 (+)NCBI
GRCm38388,950,899 - 89,079,375 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036162956   ⟹   XP_036018849
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,857,900 - 88,930,387 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036162957   ⟹   XP_036018850
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,891,937 - 88,986,682 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001783666
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,857,900 - 88,933,740 (+)NCBI
GRCm38388,950,597 - 89,026,433 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004941297
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39388,857,900 - 88,914,525 (+)NCBI
Sequence:
RefSeq Acc Id: NP_619620   ⟸   NM_138679
- UniProtKB: Q8BTX0 (UniProtKB/Swiss-Prot),   Q8BM69 (UniProtKB/Swiss-Prot),   Q80VY5 (UniProtKB/Swiss-Prot),   Q3U598 (UniProtKB/Swiss-Prot),   E9QNM2 (UniProtKB/Swiss-Prot),   Q8BZY6 (UniProtKB/Swiss-Prot),   Q99MY8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006501205   ⟸   XM_006501142
- Peptide Label: isoform X1
- UniProtKB: Q8BTX0 (UniProtKB/Swiss-Prot),   Q8BM69 (UniProtKB/Swiss-Prot),   Q80VY5 (UniProtKB/Swiss-Prot),   Q3U598 (UniProtKB/Swiss-Prot),   E9QNM2 (UniProtKB/Swiss-Prot),   Q8BZY6 (UniProtKB/Swiss-Prot),   Q99MY8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006501204   ⟸   XM_006501141
- Peptide Label: isoform X1
- UniProtKB: Q8BTX0 (UniProtKB/Swiss-Prot),   Q8BM69 (UniProtKB/Swiss-Prot),   Q80VY5 (UniProtKB/Swiss-Prot),   Q3U598 (UniProtKB/Swiss-Prot),   E9QNM2 (UniProtKB/Swiss-Prot),   Q8BZY6 (UniProtKB/Swiss-Prot),   Q99MY8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017174988   ⟸   XM_017319499
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017174991   ⟸   XM_017319502
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_030108328   ⟸   XM_030252468
- Peptide Label: isoform X1
- UniProtKB: Q99MY8 (UniProtKB/Swiss-Prot),   Q8BTX0 (UniProtKB/Swiss-Prot),   Q8BM69 (UniProtKB/Swiss-Prot),   Q80VY5 (UniProtKB/Swiss-Prot),   Q3U598 (UniProtKB/Swiss-Prot),   E9QNM2 (UniProtKB/Swiss-Prot),   Q8BZY6 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000088451   ⟸   ENSMUST00000090933
Ensembl Acc Id: ENSMUSP00000140251   ⟸   ENSMUST00000186583
RefSeq Acc Id: XP_036018849   ⟸   XM_036162956
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036018850   ⟸   XM_036162957
- Peptide Label: isoform X4
Protein Domains
AWS   BAH   Bromo   Post-SET   SET

Promoters
RGD ID:6881190
Promoter ID:EPDNEW_M4046
Type:multiple initiation site
Name:Ash1l_1
Description:Mus musculus ASH1 like histone lysine methyltransferase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4047  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38388,950,439 - 88,950,499EPDNEW
RGD ID:6881192
Promoter ID:EPDNEW_M4047
Type:initiation region
Name:Ash1l_2
Description:Mus musculus ASH1 like histone lysine methyltransferase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M4046  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38388,950,687 - 88,950,747EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2183158 AgrOrtholog
Ensembl Genes ENSMUSG00000028053 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000090933 ENTREZGENE
  ENSMUST00000090933.5 UniProtKB/Swiss-Prot
  ENSMUST00000186583 ENTREZGENE
  ENSMUST00000186583.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.920.10 UniProtKB/Swiss-Prot
  2.170.270.10 UniProtKB/Swiss-Prot
  2.30.30.490 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
InterPro AT_hook_DNA-bd_motif UniProtKB/Swiss-Prot
  AWS_dom UniProtKB/Swiss-Prot
  BAH_dom UniProtKB/Swiss-Prot
  BAH_sf UniProtKB/Swiss-Prot
  Bromo_ASH1L UniProtKB/Swiss-Prot
  Bromodomain UniProtKB/Swiss-Prot
  Bromodomain-like_sf UniProtKB/Swiss-Prot
  PHD_ASH1L UniProtKB/Swiss-Prot
  Post-SET_dom UniProtKB/Swiss-Prot
  SET_dom UniProtKB/Swiss-Prot
  SET_dom_sf UniProtKB/Swiss-Prot
  Zinc_finger_PHD-type_CS UniProtKB/Swiss-Prot
  Znf_FYVE_PHD UniProtKB/Swiss-Prot
  Znf_PHD UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report mmu:192195 UniProtKB/Swiss-Prot
MGD MGI:2183158 ENTREZGENE
NCBI Gene 192195 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 UniProtKB/Swiss-Prot
  SET-BINDING PROTEIN UniProtKB/Swiss-Prot
Pfam AWS UniProtKB/Swiss-Prot
  BAH UniProtKB/Swiss-Prot
  Bromodomain UniProtKB/Swiss-Prot
  PHD_5 UniProtKB/Swiss-Prot
  SET UniProtKB/Swiss-Prot
PhenoGen Ash1l PhenoGen
PROSITE AWS UniProtKB/Swiss-Prot
  BAH UniProtKB/Swiss-Prot
  BROMODOMAIN_2 UniProtKB/Swiss-Prot
  POST_SET UniProtKB/Swiss-Prot
  SET UniProtKB/Swiss-Prot
  ZF_PHD_1 UniProtKB/Swiss-Prot
SMART AT_hook UniProtKB/Swiss-Prot
  AWS UniProtKB/Swiss-Prot
  BAH UniProtKB/Swiss-Prot
  BROMO UniProtKB/Swiss-Prot
  PHD UniProtKB/Swiss-Prot
  SET UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47370 UniProtKB/Swiss-Prot
  SSF57903 UniProtKB/Swiss-Prot
  SSF82199 UniProtKB/Swiss-Prot
UniProt ASH1L_MOUSE UniProtKB/Swiss-Prot
  E9QNM2 ENTREZGENE
  Q3U598 ENTREZGENE
  Q80VY5 ENTREZGENE
  Q8BM69 ENTREZGENE
  Q8BTX0 ENTREZGENE
  Q8BZY6 ENTREZGENE
  Q99MY8 ENTREZGENE
UniProt Secondary E9QNM2 UniProtKB/Swiss-Prot
  Q3U598 UniProtKB/Swiss-Prot
  Q80VY5 UniProtKB/Swiss-Prot
  Q8BM69 UniProtKB/Swiss-Prot
  Q8BTX0 UniProtKB/Swiss-Prot
  Q8BZY6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-31 Ash1l  ASH1 like histone lysine methyltransferase    ash1 (absent, small, or homeotic)-like (Drosophila)  Symbol and/or name change 5135510 APPROVED