Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Btbd7 | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of BTBD7 mRNA | CTD | PMID:22206623 | Btbd7 | Mouse | 17beta-estradiol | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of BTBD7 mRNA | CTD | PMID:19167446 | Btbd7 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of BTBD7 mRNA | CTD | PMID:32109520 | Btbd7 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of BTBD7 mRNA | CTD | PMID:33387578 | Btbd7 | Mouse | 2-methylcholine | affects expression | ISO | BTBD7 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of BTBD7 mRNA | CTD | PMID:21179406 | Btbd7 | Mouse | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of BTBD7 mRNA | CTD | PMID:28628672 | Btbd7 | Mouse | 4,4'-sulfonyldiphenol | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of BTBD7 mRNA | CTD | PMID:28628672 | Btbd7 | Mouse | acrolein | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BTBD7 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of BTBD7 mRNA | CTD | PMID:32699268 | Btbd7 | Mouse | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of BTBD7 mRNA | CTD | PMID:19770486 | Btbd7 | Mouse | aflatoxin B1 | decreases methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of BTBD7 gene | CTD | PMID:27153756 | Btbd7 | Mouse | alpha-pinene | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BTBD7 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of BTBD7 mRNA | CTD | PMID:32699268 | Btbd7 | Mouse | antirheumatic drug | increases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of BTBD7 mRNA | CTD | PMID:24449571 | Btbd7 | Mouse | arsane | affects methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Arsenic affects the methylation of BTBD7 gene | CTD | PMID:25304211 | Btbd7 | Mouse | arsenic atom | affects methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Arsenic affects the methylation of BTBD7 gene | CTD | PMID:25304211 | Btbd7 | Mouse | avobenzone | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | avobenzone results in decreased expression of BTBD7 mRNA | CTD | PMID:29981360 | Btbd7 | Mouse | avobenzone | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | avobenzone inhibits the reaction [IFI27 mRNA results in increased expression of BTBD7 mRNA] and IFI27 mRNA inhibits the reaction [avobenzone results in decreased expression of BTBD7 mRNA] | CTD | PMID:29981360 | Btbd7 | Mouse | benzo[a]pyrene | increases methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of BTBD7 3' UTR and Benzo(a)pyrene results in increased methylation of BTBD7 5' UTR | CTD | PMID:27901495 | Btbd7 | Mouse | benzo[a]pyrene diol epoxide I | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Btbd7 | Mouse | benzo[a]pyrene diol epoxide I | increases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Btbd7 | Mouse | bisphenol A | affects expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of BTBD7 mRNA | CTD | PMID:25181051 | Btbd7 | Mouse | bisphenol A | decreases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of BTBD7 mRNA | CTD | PMID:32145629 | Btbd7 | Mouse | butanal | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of BTBD7 mRNA | CTD | PMID:26079696 | Btbd7 | Mouse | CGP 52608 | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to BTBD7 gene] | CTD | PMID:28238834 | Btbd7 | Mouse | copper atom | increases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of BTBD7 mRNA | CTD | PMID:26033743 | Btbd7 | Mouse | copper(0) | increases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of BTBD7 mRNA | CTD | PMID:26033743 | Btbd7 | Mouse | copper(II) sulfate | increases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of BTBD7 mRNA | CTD | PMID:19549813 | Btbd7 | Mouse | coumestrol | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of BTBD7 mRNA | CTD | PMID:19167446 | Btbd7 | Mouse | dexamethasone | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of BTBD7 mRNA | CTD | PMID:28628672 | Btbd7 | Mouse | disodium selenite | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of BTBD7 mRNA | CTD | PMID:18175754 | Btbd7 | Mouse | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of BTBD7 mRNA | CTD | PMID:35436446 | Btbd7 | Mouse | ethyl methanesulfonate | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of BTBD7 mRNA | CTD | PMID:23649840 | Btbd7 | Mouse | formaldehyde | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of BTBD7 mRNA | CTD | PMID:20655997 | Btbd7 | Mouse | FR900359 | decreases phosphorylation | ISO | BTBD7 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of BTBD7 protein | CTD | PMID:37730182 | Btbd7 | Mouse | indometacin | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of BTBD7 mRNA | CTD | PMID:28628672 | Btbd7 | Mouse | lead diacetate | decreases expression | EXP | | 6480464 | lead acetate results in decreased expression of BTBD7 mRNA | CTD | PMID:21829687 | Btbd7 | Mouse | niclosamide | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Niclosamide results in decreased expression of BTBD7 mRNA | CTD | PMID:36318118 | Btbd7 | Mouse | orphenadrine | affects expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Orphenadrine affects the expression of BTBD7 mRNA | CTD | PMID:23665939 | Btbd7 | Mouse | ozone | multiple interactions | ISO | BTBD7 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BTBD7 mRNA more ... | CTD | PMID:32699268 | Btbd7 | Mouse | paracetamol | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of BTBD7 mRNA | CTD | PMID:21420995 | Btbd7 | Mouse | pentanal | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | pentanal results in decreased expression of BTBD7 mRNA | CTD | PMID:26079696 | Btbd7 | Mouse | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of BTBD7 mRNA | CTD | PMID:23091169 | Btbd7 | Mouse | silicon dioxide | increases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of BTBD7 mRNA and Silicon Dioxide results in increased expression of BTBD7 mRNA | CTD | PMID:25351596 and PMID:25895662 | Btbd7 | Mouse | silver atom | decreases expression | EXP | | 6480464 | Silver results in decreased expression of BTBD7 mRNA | CTD | PMID:27131904 | Btbd7 | Mouse | silver(0) | decreases expression | EXP | | 6480464 | Silver results in decreased expression of BTBD7 mRNA | CTD | PMID:27131904 | Btbd7 | Mouse | sodium arsenate | increases expression | EXP | | 6480464 | sodium arsenate results in increased expression of BTBD7 mRNA | CTD | PMID:21795629 | Btbd7 | Mouse | tamoxifen | decreases expression | EXP | | 6480464 | Tamoxifen results in decreased expression of BTBD7 mRNA | CTD | PMID:25123088 | Btbd7 | Mouse | thioacetamide | increases expression | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of BTBD7 mRNA | CTD | PMID:23411599 and PMID:34492290 | Btbd7 | Mouse | titanium dioxide | increases methylation | EXP | | 6480464 | titanium dioxide results in increased methylation of BTBD7 gene | CTD | PMID:35295148 | Btbd7 | Mouse | trichloroethene | decreases methylation | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased methylation of BTBD7 gene | CTD | PMID:27618143 | Btbd7 | Mouse | triphenyl phosphate | affects expression | ISO | BTBD7 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of BTBD7 mRNA | CTD | PMID:37042841 | Btbd7 | Mouse | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of BTBD7 mRNA | CTD | PMID:28973697 | Btbd7 | Mouse | valproic acid | decreases methylation | ISO | BTBD7 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of BTBD7 gene | CTD | PMID:29154799 | Btbd7 | Mouse | valproic acid | decreases expression | ISO | BTBD7 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of BTBD7 mRNA | CTD | PMID:27188386 | Btbd7 | Mouse | valproic acid | affects splicing | ISO | Btbd7 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of BTBD7 mRNA | CTD | PMID:29427782 | |