Tiparp (TCDD-inducible poly(ADP-ribose) polymerase) - Rat Genome Database

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Gene: Tiparp (TCDD-inducible poly(ADP-ribose) polymerase) Mus musculus
Analyze
Symbol: Tiparp
Name: TCDD-inducible poly(ADP-ribose) polymerase
RGD ID: 1314637
MGI Page MGI
Description: Enables NAD+ ADP-ribosyltransferase activity. Acts upstream of or within several processes, including androgen metabolic process; face morphogenesis; and vasculogenesis. Predicted to be active in nucleus. Is expressed in bladder; reproductive system; telencephalon; and tongue. Orthologous to human TIPARP (TCDD inducible poly(ADP-ribose) polymerase).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosyltransferase diphtheria toxin-like 14; ARTD14; AW558171; DDF1; P; PA; PARP-7; PARP7; TCDD-inducible poly [ADP-ribose] polymerase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39365,435,868 - 65,462,939 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl365,435,831 - 65,462,939 (+)EnsemblGRCm39 Ensembl
GRCm38365,528,447 - 65,555,518 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl365,528,410 - 65,555,518 (+)EnsemblGRCm38mm10GRCm38
MGSCv37365,332,369 - 65,359,440 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36365,616,376 - 65,643,447 (+)NCBIMGSCv36mm8
Celera365,663,643 - 65,691,202 (+)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(S)-nicotine  (EXP)
1,2,3,7,8-Pentachlorodibenzodioxin  (ISO)
1,2-dimethylhydrazine  (EXP)
1,8-Dinitropyrene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,3',4,4',5-Hexachlorobiphenyl  (ISO)
2,3,4,7,8-Pentachlorodibenzofuran  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-butoxyethanol  (EXP)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3-methylcholanthrene  (EXP,ISO)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxynon-2-enal  (EXP)
4-vinylcyclohexene dioxide  (EXP)
7,12-dimethyltetraphene  (EXP)
8-Br-cAMP  (ISO)
acrylamide  (ISO)
actinomycin D  (EXP)
adefovir pivoxil  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-naphthoflavone  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
Benzo[k]fluoranthene  (EXP,ISO)
beta-naphthoflavone  (EXP,ISO)
bilirubin IXalpha  (ISO)
bisphenol A  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
chloroprene  (ISO)
chlorpromazine  (ISO)
cidofovir anhydrous  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clodronic acid  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cycloheximide  (EXP)
cyclosporin A  (EXP,ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (EXP)
dibenzofuran  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (ISO)
diuron  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenofibrate  (ISO)
fluoranthene  (EXP,ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
gentamycin  (ISO)
hydrogen cyanide  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
ibuprofen  (ISO)
inulin  (EXP)
iron dichloride  (ISO)
isobutanol  (ISO)
lactacystin  (EXP)
lead(0)  (ISO)
leflunomide  (ISO)
lucanthone  (ISO)
menadione  (EXP,ISO)
metformin  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mifepristone  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phytoestrogen  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
poly(vinylpyrrolidone)  (ISO)
potassium cyanide  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
puromycin  (EXP)
raloxifene  (ISO)
resveratrol  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
Soman  (ISO)
succimer  (EXP)
tamoxifen  (EXP,ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
tryptophan  (ISO)
tunicamycin  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood vessel morphology  (IAGP)
abnormal frontal bone morphology  (IAGP)
abnormal heart morphology  (IEA)
abnormal kidney morphology  (IAGP)
abnormal neurocranium morphology  (IAGP)
abnormal palate morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal skin morphology  (IEA)
abnormal smooth muscle morphology  (IAGP)
abnormal spleen morphology  (IEA)
abnormal sternum morphology  (IAGP)
abnormal thymus involution  (IAGP)
anemia  (IAGP)
asymmetric sternocostal joints  (IAGP)
broad snout  (IAGP)
decreased circulating estradiol level  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased fasting circulating glucose level  (IAGP)
decreased hematocrit  (IAGP)
decreased hemoglobin content  (IAGP)
decreased litter size  (IAGP)
decreased palatine bone horizontal plate size  (IAGP)
enlarged heart  (IEA)
enlarged liver  (IAGP)
enlarged ovary  (IAGP)
enlarged spleen  (IEA)
enlarged uterus  (IAGP)
female infertility  (IAGP)
hemorrhage  (IAGP)
hepatic steatosis  (IAGP)
hydrometra  (IEA)
increased blood urea nitrogen level  (IAGP)
increased circulating alanine transaminase level  (IAGP)
increased corpora lutea number  (IAGP)
increased physiological sensitivity to xenobiotic  (IAGP)
increased susceptibility to weight loss  (IAGP)
increased susceptibility to xenobiotic induced morbidity/mortality  (IAGP)
increased tertiary ovarian follicle number  (IAGP)
kidney inflammation  (IAGP)
liver degeneration  (IAGP)
long gestation period  (IAGP)
ovary cyst  (IAGP)
pale kidney  (IAGP)
polychromatophilia  (IAGP)
postnatal lethality  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
prolonged estrous cycle  (IAGP)
reduced female fertility  (IAGP)
reticulocytosis  (IAGP)
scaly skin  (IEA)
short maxilla  (IAGP)
short nasal bone  (IAGP)
short premaxilla  (IAGP)
short snout  (IAGP)
small kidney  (IAGP)
small presphenoid bone  (IAGP)
small superior vagus ganglion  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation. Barkauskaite E, etal., Mol Cell. 2015 Jun 18;58(6):935-46. doi: 10.1016/j.molcel.2015.05.007.
2. Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor. Hsu CN, etal., Int J Mol Sci. 2020 Jun 26;21(12):4552. doi: 10.3390/ijms21124552.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11716501   PMID:12147270   PMID:12477932   PMID:12520002   PMID:15142957  
PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17143286   PMID:17967808   PMID:19056881   PMID:21156168   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22615585  
PMID:23275542   PMID:24194600   PMID:24806346   PMID:25975270   PMID:26814197   PMID:26984772   PMID:27089381   PMID:28213497   PMID:29873790   PMID:29938598   PMID:31083300   PMID:31694960  
PMID:31704703   PMID:33572475   PMID:34129049   PMID:34146543   PMID:34453220   PMID:35055106   PMID:37509350  


Genomics

Comparative Map Data
Tiparp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39365,435,868 - 65,462,939 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl365,435,831 - 65,462,939 (+)EnsemblGRCm39 Ensembl
GRCm38365,528,447 - 65,555,518 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl365,528,410 - 65,555,518 (+)EnsemblGRCm38mm10GRCm38
MGSCv37365,332,369 - 65,359,440 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36365,616,376 - 65,643,447 (+)NCBIMGSCv36mm8
Celera365,663,643 - 65,691,202 (+)NCBICelera
Cytogenetic Map3E1NCBI
cM Map330.2NCBI
TIPARP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383156,674,590 - 156,706,770 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3156,673,235 - 156,706,770 (+)EnsemblGRCh38hg38GRCh38
GRCh373156,392,379 - 156,424,559 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363157,875,073 - 157,907,228 (+)NCBINCBI36Build 36hg18NCBI36
Build 343157,875,080 - 157,907,236NCBI
Celera3154,815,555 - 154,847,904 (+)NCBICelera
Cytogenetic Map3q25.31NCBI
HuRef3153,788,071 - 153,820,428 (+)NCBIHuRef
CHM1_13156,353,862 - 156,386,212 (+)NCBICHM1_1
T2T-CHM13v2.03159,449,273 - 159,481,452 (+)NCBIT2T-CHM13v2.0
Tiparp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82152,063,769 - 152,090,414 (+)NCBIGRCr8
mRatBN7.22149,753,682 - 149,780,327 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2149,753,682 - 149,780,327 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2156,856,323 - 156,882,972 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02154,906,806 - 154,933,457 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02149,539,488 - 149,566,139 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02157,316,293 - 157,342,979 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2157,316,266 - 157,341,469 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02176,685,223 - 176,711,918 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42155,312,341 - 155,339,357 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12155,264,128 - 155,288,955 (+)NCBI
Celera2144,165,974 - 144,192,615 (+)NCBICelera
Cytogenetic Map2q31NCBI
Tiparp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554487,687,668 - 7,716,707 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554487,687,668 - 7,716,481 (+)NCBIChiLan1.0ChiLan1.0
TIPARP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22154,590,906 - 154,624,445 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13154,595,679 - 154,629,176 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03153,730,307 - 153,762,442 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13161,784,004 - 161,816,525 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3161,783,999 - 161,816,525 (+)Ensemblpanpan1.1panPan2
TIPARP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12350,253,645 - 50,279,615 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2350,249,327 - 50,280,144 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2350,124,312 - 50,154,046 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02350,883,652 - 50,913,363 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2350,883,621 - 50,913,330 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12350,467,974 - 50,497,675 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02350,518,863 - 50,548,568 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02350,805,561 - 50,835,202 (+)NCBIUU_Cfam_GSD_1.0
Tiparp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560286,021,871 - 86,049,211 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365193,684,515 - 3,712,081 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365193,683,972 - 3,712,081 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIPARP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1396,496,439 - 96,525,777 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11396,496,386 - 96,524,879 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213104,603,588 - 104,630,839 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TIPARP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11534,041,208 - 34,073,428 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1534,039,657 - 34,073,319 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660416,662,900 - 6,694,976 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tiparp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473034,262,468 - 34,293,087 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473034,262,630 - 34,293,034 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tiparp
968 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:528
Count of miRNA genes:353
Interacting mature miRNAs:426
Transcripts:ENSMUST00000047906, ENSMUST00000130705, ENSMUST00000154094
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1300961Bh4p_mbar holding four paws (mouse)Not determined33183785465837997Mouse
10412073Ssen2_msuseptibility to Sendai virus 2 (mouse)Not determined33353546567535615Mouse
9587784Afw13_mabdominal fat weight QTL 13 (mouse)Not determined33375204567752228Mouse
10043882Bwtq13_mbody weight QTL 13 (mouse)Not determined33375204567752228Mouse
15039332Nmrs6_mNAFLD-associated magnetic resonance shift 6 (mouse)33417074168170741Mouse
15039336Nmrs2_mNAFLD-associated magnetic resonance shift 2 (mouse)33457610368576103Mouse
18337272Bmd46_mbone mineral density 46, males (mouse)33540742169407421Mouse
14746977Manh53_mmandible shape 53 (mouse)33592528069925280Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
1300587Aod2_mautoimmune ovarian dysgenesis 2 (mouse)Not determined33717974268716946Mouse
11041901Lmr11b_mleishmaniasis resistance 11b (mouse)33970410273704231Mouse
11039513Ltpr3a_mLeishmania tropica response 3a (mouse)33970410273704231Mouse
1301585Cd4ts1_mCD4 T cell subset 1 (mouse)Not determined33970410273704231Mouse
10755516Amzn1_manatomical modifier of Zfp423 1 (mouse)33970410273704231Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
4141079Ath23_matherosclerosis 23 (mouse)Not determined4935758183357581Mouse
1300895Hdl5_mHDL level 5 (mouse)Not determined34949500583495118Mouse
1301824Susp_msuppressor of superoxide production (mouse)Not determined34949500583495118Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35262550986625745Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35262550986625745Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35262550986625745Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35292318386923183Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse

Markers in Region
AW558171  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38365,554,634 - 65,554,758UniSTSGRCm38
MGSCv37365,358,556 - 65,358,680UniSTSGRCm37
Celera365,690,318 - 65,690,442UniSTS
Cytogenetic Map3E1UniSTS
Whitehead/MRC_RH3590.8UniSTS
09.MMHAP5FRC9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37365,342,640 - 65,342,792UniSTSGRCm37
Celera365,674,453 - 65,674,605UniSTS
Celera365,673,917 - 65,674,069UniSTS
Whitehead_YAC3 UniSTS
AI599420  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38365,554,380 - 65,554,542UniSTSGRCm38
MGSCv37365,358,302 - 65,358,464UniSTSGRCm37
Celera365,690,064 - 65,690,226UniSTS
Cytogenetic Map3E1UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000047906   ⟹   ENSMUSP00000048051
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl365,435,831 - 65,462,939 (+)Ensembl
GRCm38.p6 Ensembl365,528,410 - 65,555,518 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130705   ⟹   ENSMUSP00000119951
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl365,435,881 - 65,455,018 (+)Ensembl
GRCm38.p6 Ensembl365,528,460 - 65,547,597 (+)Ensembl
RefSeq Acc Id: ENSMUST00000154094
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl365,453,461 - 65,460,053 (+)Ensembl
GRCm38.p6 Ensembl365,546,040 - 65,552,632 (+)Ensembl
RefSeq Acc Id: NM_178892   ⟹   NP_849223
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39365,435,868 - 65,462,939 (+)NCBI
GRCm38365,528,447 - 65,555,518 (+)ENTREZGENE
MGSCv37365,332,369 - 65,359,440 (+)RGD
Celera365,663,643 - 65,691,202 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_849223   ⟸   NM_178892
- UniProtKB: Q3UD50 (UniProtKB/Swiss-Prot),   Q8C032 (UniProtKB/Swiss-Prot),   Q8C1B2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000119951   ⟸   ENSMUST00000130705
RefSeq Acc Id: ENSMUSP00000048051   ⟸   ENSMUST00000047906
Protein Domains
C3H1-type   PARP catalytic   WWE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C1B2-F1-model_v2 AlphaFold Q8C1B2 1-657 view protein structure

Promoters
RGD ID:6833276
Promoter ID:MM_KWN:34511
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000052185,   OTTMUST00000052639,   OTTMUST00000052640
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36365,331,621 - 65,332,977 (-)MPROMDB
RGD ID:6880808
Promoter ID:EPDNEW_M3855
Type:initiation region
Name:Tiparp_1
Description:Mus musculus TCDD-inducible poly(ADP-ribose) polymerase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38365,528,447 - 65,528,507EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2159210 AgrOrtholog
Ensembl Genes ENSMUSG00000034640 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000047906 ENTREZGENE
  ENSMUST00000047906.10 UniProtKB/Swiss-Prot
  ENSMUST00000130705.2 UniProtKB/TrEMBL
Gene3D-CATH 3.90.228.10 UniProtKB/Swiss-Prot
InterPro Poly(ADP-ribose)pol_cat_dom UniProtKB/Swiss-Prot
  WWE-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WWE_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:99929 UniProtKB/Swiss-Prot
MGD MGI:2159210 ENTREZGENE
NCBI Gene 99929 ENTREZGENE
PANTHER POLY [ADP-RIBOSE] POLYMERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN MONO-ADP-RIBOSYLTRANSFERASE TIPARP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PARP UniProtKB/Swiss-Prot
PhenoGen Tiparp PhenoGen
PROSITE PARP_CATALYTIC UniProtKB/Swiss-Prot
  WWE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_C3H1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP ADP-ribosylation UniProtKB/Swiss-Prot
  SSF117839 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z7U2_MOUSE UniProtKB/TrEMBL
  PARPT_MOUSE UniProtKB/Swiss-Prot
  Q3UD50 ENTREZGENE
  Q8C032 ENTREZGENE
  Q8C1B2 ENTREZGENE
UniProt Secondary Q3UD50 UniProtKB/Swiss-Prot
  Q8C032 UniProtKB/Swiss-Prot