Dennd6a (DENN domain containing 6A) - Rat Genome Database

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Gene: Dennd6a (DENN domain containing 6A) Mus musculus
Analyze
Symbol: Dennd6a
Name: DENN domain containing 6A
RGD ID: 1314464
MGI Page MGI
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of cell-cell adhesion mediated by cadherin. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Predicted to be active in recycling endosome. Orthologous to human DENND6A (DENN domain containing 6A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A630054L15Rik; DENN domain-containing protein 6A; DENN/MADD domain containing 6A; Fam11; Fam116a; family with sequence similarity 116, member A; hypothetical protein LOC211922; mFLJ00229; MGC38041
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391426,295,013 - 26,355,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1426,295,011 - 26,355,477 (+)EnsemblGRCm39 Ensembl
GRCm381426,573,858 - 26,634,322 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1426,573,856 - 26,634,322 (+)EnsemblGRCm38mm10GRCm38
MGSCv371427,399,036 - 27,451,586 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361425,412,745 - 25,461,593 (+)NCBIMGSCv36mm8
Celera1422,823,047 - 22,874,957 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1416.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15449545   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18799693  
PMID:21873635   PMID:24200680   PMID:26496610   PMID:27899360   PMID:31138677   PMID:38355793  


Genomics

Comparative Map Data
Dennd6a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391426,295,013 - 26,355,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1426,295,011 - 26,355,477 (+)EnsemblGRCm39 Ensembl
GRCm381426,573,858 - 26,634,322 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1426,573,856 - 26,634,322 (+)EnsemblGRCm38mm10GRCm38
MGSCv371427,399,036 - 27,451,586 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361425,412,745 - 25,461,593 (+)NCBIMGSCv36mm8
Celera1422,823,047 - 22,874,957 (+)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1416.09NCBI
DENND6A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38357,625,454 - 57,693,077 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl357,625,454 - 57,693,077 (-)EnsemblGRCh38hg38GRCh38
GRCh37357,611,181 - 57,678,804 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36357,586,224 - 57,653,844 (-)NCBINCBI36Build 36hg18NCBI36
Celera357,624,256 - 57,692,688 (-)NCBICelera
Cytogenetic Map3p14.3NCBI
HuRef357,708,594 - 57,776,280 (-)NCBIHuRef
CHM1_1357,561,278 - 57,628,877 (-)NCBICHM1_1
T2T-CHM13v2.0357,665,829 - 57,733,445 (-)NCBIT2T-CHM13v2.0
Dennd6a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8161,843,803 - 1,892,165 (+)NCBIGRCr8
mRatBN7.2161,837,019 - 1,885,420 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl161,837,059 - 1,885,420 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx161,843,688 - 1,892,050 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0162,989,384 - 3,037,744 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0161,850,139 - 1,898,501 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0162,278,701 - 2,327,062 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl162,278,701 - 2,327,062 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0162,252,208 - 2,289,395 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0162,297,248 - 2,302,165 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4161,896,071 - 1,944,337 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1161,876,717 - 1,944,327 (+)NCBI
Celera161,806,443 - 1,854,294 (+)NCBICelera
Cytogenetic Map16p16NCBI
Dennd6a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554307,327,602 - 7,397,670 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554307,327,602 - 7,396,961 (-)NCBIChiLan1.0ChiLan1.0
DENND6A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2257,593,496 - 57,665,615 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1357,598,266 - 57,668,504 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0357,558,551 - 57,627,298 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1358,978,866 - 59,046,737 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl358,978,866 - 59,046,737 (-)Ensemblpanpan1.1panPan2
DENND6A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12032,780,529 - 32,830,388 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2032,780,579 - 32,830,478 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2032,668,669 - 32,758,618 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02033,013,800 - 33,103,659 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2033,054,003 - 33,103,575 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12032,469,126 - 32,558,931 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02032,827,460 - 32,917,253 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02032,997,818 - 33,087,850 (+)NCBIUU_Cfam_GSD_1.0
Dennd6a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118174,801,419 - 174,871,721 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364737,939,971 - 8,010,628 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364737,939,992 - 8,010,304 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DENND6A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1339,462,269 - 39,524,080 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11339,456,957 - 39,524,110 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21343,386,676 - 43,444,348 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DENND6A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12218,925,960 - 18,993,689 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2218,924,829 - 18,993,575 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041147,875,453 - 147,945,903 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dennd6a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624821376,525 - 446,583 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624821374,615 - 446,656 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dennd6a
1753 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1120
Count of miRNA genes:608
Interacting mature miRNAs:733
Transcripts:ENSMUST00000037585
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
27226748Femd8_mfemur midshaft diameter 8, 10 week (mouse)141376927346737457Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
11532711Sluc40_msusceptibility to lung cancer 40 (mouse)14127379943Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse
4141265Appd2_mAPP associated premature death 2 (mouse)Not determined14594555230114862Mouse
1301372Sluc13_msusceptibility to lung cancer 13 (mouse)Not determined141882760452827726Mouse
4141550Dbm3_mdiabetes modifier 3 (mouse)Not determined514347339143596Mouse
1300544Hypn_mhyperinsulinemia (mouse)Not determined141516061649160765Mouse
1301991Wta3_mweight adult 3 (mouse)Not determined14388747337887650Mouse
4141864Mrdq4_mmodifier of retinal degeneration QTL 4 (mouse)Not determined992324548765082Mouse
1300779Dyscalc4_mdystrophic cardiac calcinosis 4 (mouse)Not determined141221287146213007Mouse
10412071Ssen3_msuseptibility to Sendai virus 3 (mouse)Not determined14126987934Mouse
14746973Manh76_mmandible shape 76 (mouse)142228721756287217Mouse
27226752Femd4_mfemur midshaft diameter 4, 5 week (mouse)141376927347237457Mouse

Markers in Region
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001134465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001285466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001285467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006518778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036158533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI595650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK054295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB666315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY467690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000037585   ⟹   ENSMUSP00000039361
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1426,300,733 - 26,355,477 (+)Ensembl
GRCm38.p6 Ensembl1426,579,578 - 26,634,322 (+)Ensembl
Ensembl Acc Id: ENSMUST00000203874   ⟹   ENSMUSP00000144906
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1426,300,716 - 26,349,568 (+)Ensembl
GRCm38.p6 Ensembl1426,579,561 - 26,628,413 (+)Ensembl
Ensembl Acc Id: ENSMUST00000224111   ⟹   ENSMUSP00000153187
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1426,295,014 - 26,351,443 (+)Ensembl
GRCm38.p6 Ensembl1426,573,859 - 26,630,288 (+)Ensembl
Ensembl Acc Id: ENSMUST00000224248   ⟹   ENSMUSP00000152966
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1426,295,011 - 26,351,738 (+)Ensembl
GRCm38.p6 Ensembl1426,573,856 - 26,630,583 (+)Ensembl
Ensembl Acc Id: ENSMUST00000224378   ⟹   ENSMUSP00000153200
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1426,295,013 - 26,351,601 (+)Ensembl
GRCm38.p6 Ensembl1426,573,858 - 26,630,446 (+)Ensembl
Ensembl Acc Id: ENSMUST00000225206
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1426,325,826 - 26,332,982 (+)Ensembl
GRCm38.p6 Ensembl1426,604,671 - 26,611,827 (+)Ensembl
RefSeq Acc Id: NM_001134465   ⟹   NP_001127937
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391426,300,705 - 26,355,477 (+)NCBI
GRCm381426,579,550 - 26,634,322 (+)NCBI
MGSCv371427,399,036 - 27,451,586 (+)RGD
Celera1422,817,354 - 22,877,184 (+)NCBI
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001285466   ⟹   NP_001272395
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391426,295,013 - 26,355,477 (+)NCBI
GRCm381426,573,858 - 26,634,322 (+)NCBI
Celera1422,817,354 - 22,877,184 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001285467   ⟹   NP_001272396
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391426,295,013 - 26,355,477 (+)NCBI
GRCm381426,573,858 - 26,634,322 (+)NCBI
Celera1422,817,354 - 22,877,184 (+)NCBI
Sequence:
RefSeq Acc Id: NM_145969   ⟹   NP_666081
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391426,300,705 - 26,349,564 (+)NCBI
GRCm381426,579,550 - 26,628,409 (+)NCBI
MGSCv371427,399,036 - 27,451,586 (+)RGD
Celera1422,817,354 - 22,877,184 (+)NCBI
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006518778   ⟹   XP_006518841
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391426,300,929 - 26,352,890 (+)NCBI
GRCm381426,579,774 - 26,631,735 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036158533   ⟹   XP_036014426
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391426,300,725 - 26,352,890 (+)NCBI
Sequence:
RefSeq Acc Id: NP_666081   ⟸   NM_145969
- Peptide Label: isoform b
- UniProtKB: Q8BH65 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001127937   ⟸   NM_001134465
- Peptide Label: isoform a
- UniProtKB: Q8K2E8 (UniProtKB/Swiss-Prot),   Q8C4Z7 (UniProtKB/Swiss-Prot),   Q8BSG0 (UniProtKB/Swiss-Prot),   Q6KAP4 (UniProtKB/Swiss-Prot),   Q3UX21 (UniProtKB/Swiss-Prot),   Q8R136 (UniProtKB/Swiss-Prot),   Q8BH65 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001272396   ⟸   NM_001285467
- Peptide Label: isoform c
- UniProtKB: Q8BH65 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001272395   ⟸   NM_001285466
- Peptide Label: isoform c
- UniProtKB: Q8BH65 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006518841   ⟸   XM_006518778
- Peptide Label: isoform X1
- UniProtKB: Q8BH65 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000144906   ⟸   ENSMUST00000203874
Ensembl Acc Id: ENSMUSP00000153187   ⟸   ENSMUST00000224111
Ensembl Acc Id: ENSMUSP00000153200   ⟸   ENSMUST00000224378
Ensembl Acc Id: ENSMUSP00000152966   ⟸   ENSMUST00000224248
Ensembl Acc Id: ENSMUSP00000039361   ⟸   ENSMUST00000037585
RefSeq Acc Id: XP_036014426   ⟸   XM_036158533
- Peptide Label: isoform X1
Protein Domains
cDENN   dDENN   uDENN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BH65-F1-model_v2 AlphaFold Q8BH65 1-605 view protein structure

Promoters
RGD ID:8681716
Promoter ID:EPDNEW_M18889
Type:initiation region
Name:Dennd6a_1
Description:Mus musculus DENN/MADD domain containing 6A , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381426,579,553 - 26,579,613EPDNEW
RGD ID:6824614
Promoter ID:MM_KWN:15991
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000037585,   UC007SSX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361427,398,666 - 27,399,492 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2442980 AgrOrtholog
Ensembl Genes ENSMUSG00000040818 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000037585 ENTREZGENE
  ENSMUST00000037585.9 UniProtKB/Swiss-Prot
  ENSMUST00000203874 ENTREZGENE
  ENSMUST00000203874.3 UniProtKB/Swiss-Prot
  ENSMUST00000224111 ENTREZGENE
  ENSMUST00000224111.2 UniProtKB/Swiss-Prot
  ENSMUST00000224248 ENTREZGENE
  ENSMUST00000224248.2 UniProtKB/Swiss-Prot
  ENSMUST00000224378.2 UniProtKB/TrEMBL
InterPro ABL9/DENND6_dom UniProtKB/Swiss-Prot
  DENND6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tripartite_DENN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:211922 UniProtKB/Swiss-Prot
MGD MGI:2442980 ENTREZGENE
NCBI Gene 211922 ENTREZGENE
PANTHER PROTEIN DENND6A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13677 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Avl9 UniProtKB/Swiss-Prot
PhenoGen Dennd6a PhenoGen
PROSITE DENN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286YDD5_MOUSE UniProtKB/TrEMBL
  DEN6A_MOUSE UniProtKB/Swiss-Prot
  Q3UX21 ENTREZGENE
  Q6KAP4 ENTREZGENE
  Q8BH65 ENTREZGENE
  Q8BSG0 ENTREZGENE
  Q8C4Z7 ENTREZGENE
  Q8K2E8 ENTREZGENE
  Q8R136 ENTREZGENE
UniProt Secondary Q3UX21 UniProtKB/Swiss-Prot
  Q6KAP4 UniProtKB/Swiss-Prot
  Q8BSG0 UniProtKB/Swiss-Prot
  Q8C4Z7 UniProtKB/Swiss-Prot
  Q8K2E8 UniProtKB/Swiss-Prot
  Q8R136 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-11-29 Dennd6a  DENN domain containing 6A  Dennd6a  DENN/MADD domain containing 6A  Symbol and/or name change 5135510 APPROVED
2012-11-27 Dennd6a  DENN/MADD domain containing 6A  Fam116a  family with sequence similarity 116, member A  Symbol and/or name change 5135510 APPROVED