Slc25a42 (solute carrier family 25, member 42) - Rat Genome Database

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Gene: Slc25a42 (solute carrier family 25, member 42) Mus musculus
Analyze
Symbol: Slc25a42
Name: solute carrier family 25, member 42
RGD ID: 1313867
MGI Page MGI
Description: Predicted to enable ADP phosphatase activity; adenine nucleotide transmembrane transporter activity; and secondary active transmembrane transporter activity. Predicted to be involved in coenzyme A biosynthetic process and purine ribonucleotide transport. Located in mitochondrial inner membrane. Orthologous to human SLC25A42 (solute carrier family 25 member 42).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2900084M01Rik; MGC37808; mitochondrial coenzyme A transporter SLC25A42; solute carrier family 25 member 42
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,636,990 - 70,664,931 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,636,990 - 70,664,955 (-)EnsemblGRCm39 Ensembl
GRCm38870,184,340 - 70,212,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,184,340 - 70,212,305 (-)EnsemblGRCm38mm10GRCm38
MGSCv37872,708,239 - 72,736,180 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,113,329 - 73,141,245 (-)NCBIMGSCv36mm8
Celera872,740,228 - 72,768,104 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12865426   PMID:14610273   PMID:14681479   PMID:16141072   PMID:16141073   PMID:18614015  
PMID:18799693   PMID:19429682   PMID:21677750   PMID:21873635   PMID:26465331   PMID:31138677   PMID:36316571  


Genomics

Comparative Map Data
Slc25a42
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,636,990 - 70,664,931 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,636,990 - 70,664,955 (-)EnsemblGRCm39 Ensembl
GRCm38870,184,340 - 70,212,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,184,340 - 70,212,305 (-)EnsemblGRCm38mm10GRCm38
MGSCv37872,708,239 - 72,736,180 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,113,329 - 73,141,245 (-)NCBIMGSCv36mm8
Celera872,740,228 - 72,768,104 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
SLC25A42
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381919,063,994 - 19,113,030 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1919,063,994 - 19,113,030 (+)EnsemblGRCh38hg38GRCh38
GRCh371919,174,803 - 19,223,839 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361919,035,808 - 19,084,694 (+)NCBINCBI36Build 36hg18NCBI36
Celera1919,079,646 - 19,128,541 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,738,683 - 18,787,725 (+)NCBIHuRef
CHM1_11919,174,500 - 19,223,537 (+)NCBICHM1_1
T2T-CHM13v2.01919,199,813 - 19,248,846 (+)NCBIT2T-CHM13v2.0
Slc25a42
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,247,874 - 19,286,598 (+)NCBIGRCr8
mRatBN7.21619,213,914 - 19,251,990 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,213,950 - 19,237,025 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1619,253,706 - 19,276,679 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,386,024 - 20,409,006 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,306,666 - 19,329,639 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,962,144 - 21,000,191 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,962,227 - 20,985,225 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,812,201 - 20,850,121 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,697,100 - 19,720,036 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1619,402,645 - 19,425,671 (+)NCBICelera
Cytogenetic Map16p14NCBI
Slc25a42
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,675,747 - 2,683,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,674,508 - 2,683,304 (-)NCBIChiLan1.0ChiLan1.0
SLC25A42
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,925,727 - 23,974,607 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,931,914 - 22,980,745 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,501,567 - 18,550,368 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,504,325 - 19,553,292 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,504,325 - 19,553,158 (+)Ensemblpanpan1.1panPan2
SLC25A42
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,043,672 - 44,074,691 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,044,665 - 44,065,282 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2043,960,305 - 43,991,326 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,531,671 - 44,562,714 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,531,676 - 44,562,648 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12043,769,080 - 43,800,107 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,178,144 - 44,209,391 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,454,014 - 44,485,059 (-)NCBIUU_Cfam_GSD_1.0
Slc25a42
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118202,741,224 - 202,770,526 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,290,362 - 2,319,501 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,290,375 - 2,319,449 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A42
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,753,371 - 58,801,832 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1258,753,363 - 58,803,356 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,580,943 - 58,599,690 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A42
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,529,048 - 17,577,092 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,529,312 - 17,577,093 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660741,743,963 - 1,793,084 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a42
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249082,033,908 - 2,056,590 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249082,033,770 - 2,056,590 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc25a42
692 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2029
Count of miRNA genes:645
Interacting mature miRNAs:768
Transcripts:ENSMUST00000063788, ENSMUST00000110127, ENSMUST00000134596, ENSMUST00000139333, ENSMUST00000150706
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83250657271740637Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3250657271740637Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3250657271740637Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3250657271740637Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84474791478748059Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84809006482090180Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84809006482090180Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84819016882190288Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84924559183245673Mouse
14746987Manh64_mmandible shape 64 (mouse)85050595884505958Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85050595884505958Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85233484386334843Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85474046188740637Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85515925889159407Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85629887290298872Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85913640493136404Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86151347995513605Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6418673698186736Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86466617698666325Mouse
11039503Ccc4_mcolitis susceptibility in the Collaborative Cross 4 (mouse)86517423778002730Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined866084397100084549Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86872247983326976Mouse

Markers in Region
Slc25a42  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8B3.3UniSTS
cM Map834.15UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000063788   ⟹   ENSMUSP00000065903
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl870,636,990 - 70,664,906 (-)Ensembl
GRCm38.p6 Ensembl870,184,340 - 70,212,256 (-)Ensembl
RefSeq Acc Id: ENSMUST00000110127   ⟹   ENSMUSP00000105754
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl870,636,990 - 70,664,955 (-)Ensembl
GRCm38.p6 Ensembl870,184,340 - 70,212,305 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134596
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl870,645,019 - 70,664,955 (-)Ensembl
GRCm38.p6 Ensembl870,192,369 - 70,212,305 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139333
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl870,636,990 - 70,664,955 (-)Ensembl
GRCm38.p6 Ensembl870,184,340 - 70,212,305 (-)Ensembl
RefSeq Acc Id: ENSMUST00000150706
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl870,640,366 - 70,664,955 (-)Ensembl
GRCm38.p6 Ensembl870,187,716 - 70,212,305 (-)Ensembl
RefSeq Acc Id: NM_001007570   ⟹   NP_001007571
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,636,990 - 70,664,931 (-)NCBI
GRCm38870,184,340 - 70,212,281 (-)ENTREZGENE
MGSCv37872,708,239 - 72,736,180 (-)RGD
Celera872,740,228 - 72,768,104 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001007571 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH25937 (Get FASTA)   NCBI Sequence Viewer  
  AAH36140 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000065903.8
  ENSMUSP00000105754
  ENSMUSP00000105754.2
GenBank Protein Q8R0Y8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001007571   ⟸   NM_001007570
- UniProtKB: Q8R0Y8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000105754   ⟸   ENSMUST00000110127
RefSeq Acc Id: ENSMUSP00000065903   ⟸   ENSMUST00000063788

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R0Y8-F1-model_v2 AlphaFold Q8R0Y8 1-318 view protein structure

Promoters
RGD ID:8667287
Promoter ID:EPDNEW_M11674
Type:initiation region
Name:Slc25a42_1
Description:Mus musculus solute carrier family 25, member 42 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38870,212,281 - 70,212,341EPDNEW
RGD ID:6843727
Promoter ID:MM_KWN:54673
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:ENSMUST00000063788
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,717,971 - 72,718,471 (-)MPROMDB
RGD ID:6843725
Promoter ID:MM_KWN:54674
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000110127,   OTTMUST00000052786,   OTTMUST00000052787,   OTTMUST00000052788,   UC009LZF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,736,111 - 72,736,922 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1920345 AgrOrtholog
Ensembl Genes ENSMUSG00000002346 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000063788.8 UniProtKB/Swiss-Prot
  ENSMUST00000110127 ENTREZGENE
  ENSMUST00000110127.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.50.40.10 UniProtKB/Swiss-Prot
InterPro DNA_mismatch_repair_CS UniProtKB/Swiss-Prot
  Graves_DC UniProtKB/Swiss-Prot
  Mit_carrier UniProtKB/Swiss-Prot
  Mitochondrial_sb/sol_carrier UniProtKB/Swiss-Prot
  Mt_carrier_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:73095 UniProtKB/Swiss-Prot
MGD MGI:1920345 ENTREZGENE
NCBI Gene 73095 ENTREZGENE
PANTHER MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42 UniProtKB/Swiss-Prot
  SOLUTE CARRIER FAMILY 25 UniProtKB/Swiss-Prot
Pfam Mito_carr UniProtKB/Swiss-Prot
PhenoGen Slc25a42 PhenoGen
PRINTS GRAVESDC UniProtKB/Swiss-Prot
  MITOCARRIER UniProtKB/Swiss-Prot
PROSITE SOLCAR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103506 UniProtKB/Swiss-Prot
UniProt Q8R0Y8 ENTREZGENE, UniProtKB/Swiss-Prot