Gene: UPP1 (uridine phosphorylase 1) Homo sapiens
Symbol: UPP1
Name: uridine phosphorylase 1
Description: This gene encodes a uridine phosphorylase, an enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded enzyme functions in the degradation and salvage of pyrimidine ribonucleosides. [provided by RefSeq, Oct 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: OTTHUMP00000159566; OTTHUMP00000208692; UDRPASE; UP; UPASE; UPase 1; UPP; urdPase 1
Mus musculus (house mouse) : Upp1 (uridine phosphorylase 1)  MGI  AGR
Rattus norvegicus (Norway rat) : Upp1 (uridine phosphorylase 1)  AGR
Chinchilla lanigera (long-tailed chinchilla) : Upp1 (uridine phosphorylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : UPP1 (uridine phosphorylase 1)
Canis lupus familiaris (dog) : LOC100856638 (uridine phosphorylase 1-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Upp1 (uridine phosphorylase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38748,088,308 - 48,108,746 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37748,128,355 - 48,148,330 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36748,094,880 - 48,114,855 (+)NCBINCBI36hg18NCBI36
Celera748,227,538 - 48,247,515 (+)NCBI
Cytogenetic Map7p12.3NCBI
HuRef748,013,793 - 48,033,924 (+)NCBIHuRef
CHM1_1748,131,900 - 48,152,030 (+)NCBICHM1_1
CRA_TCAGchr7v2748,168,224 - 48,188,201 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on UPP1
AGR Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313669
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2017-12-26
Status: ACTIVE