Rnf2 (ring finger protein 2) - Rat Genome Database

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Gene: Rnf2 (ring finger protein 2) Mus musculus
Analyze
Symbol: Rnf2
Name: ring finger protein 2
RGD ID: 1313549
MGI Page MGI
Description: Enables chromatin binding activity and histone H2AK119 ubiquitin ligase activity. Involved in germ cell development and negative regulation of transcription by RNA polymerase II. Acts upstream of or within with a positive effect on chromatin organization. Acts upstream of or within with a negative effect on gene expression. Acts upstream of or within anterior/posterior axis specification; gastrulation with mouth forming second; and mitotic cell cycle. Located in euchromatin; nuclear body; and sex chromatin. Part of PRC1 complex. Is active in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early embryo; genitourinary system; limb; and retina. Human ortholog(s) of this gene implicated in Luo-Schoch-Yamamoto syndrome. Orthologous to human RNF2 (ring finger protein 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI326319; AI450156; AU019207; di; dinG; E3 ubiquitin-protein ligase RING2; Rin; RING finger protein 1B; RING-type E3 ubiquitin transferase RING2; Ring1B
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm18023  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391151,345,159 - 151,376,562 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1151,333,755 - 151,376,706 (-)EnsemblGRCm39 Ensembl
GRCm381151,469,398 - 151,500,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1151,458,004 - 151,500,955 (-)EnsemblGRCm38mm10GRCm38
MGSCv371153,316,536 - 153,347,953 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,231,624 - 153,263,041 (-)NCBIMGSCv36mm8
Celera1153,898,457 - 153,929,917 (-)NCBICelera
Cytogenetic Map1G1NCBI
cM Map164.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA)
euchromatin  (IDA)
heterochromatin  (IDA)
MLL1 complex  (ISO,ISS)
nuclear body  (IDA,ISO)
nucleoplasm  (ISO)
nucleus  (IDA,ISO)
PcG protein complex  (IBA,IDA,ISO)
PRC1 complex  (IDA,ISO)
sex chromatin  (IDA)
ubiquitin ligase complex  (IBA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. PRC1 complex diversity: where is it taking us? Gil J and O'Loghlen A, Trends Cell Biol. 2014 Jul 22. pii: S0962-8924(14)00102-0. doi: 10.1016/j.tcb.2014.06.005.
2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
5. The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma. Martinez-Romero C, etal., J Pathol. 2009 Oct;219(2):205-13. doi: 10.1002/path.2585.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Simon JA and Kingston RE, Mol Cell. 2013 Mar 7;49(5):808-24. doi: 10.1016/j.molcel.2013.02.013.
13. Retinal proteomic changes under different ischemic conditions - implication of an epigenetic regulatory mechanism. Stowell C, etal., Int J Physiol Pathophysiol Pharmacol. 2010 Jun 30;2(2):148-160.
14. Polycomb group proteins are essential for spinal cord development. Wang C, etal., Front Biosci (Landmark Ed). 2010 Jun 1;15:1018-22.
Additional References at PubMed
PMID:9312051   PMID:9627119   PMID:10349636   PMID:10369680   PMID:10512203   PMID:10922068   PMID:11042159   PMID:11060235   PMID:11076861   PMID:12167161   PMID:12183370   PMID:12477932  
PMID:12520002   PMID:12589020   PMID:12904583   PMID:14557078   PMID:14610273   PMID:15489334   PMID:15509584   PMID:15525528   PMID:15741318   PMID:15761153   PMID:15782199   PMID:15840001  
PMID:15889154   PMID:16024804   PMID:16107646   PMID:16141072   PMID:16141073   PMID:16359901   PMID:16624538   PMID:16625203   PMID:16687444   PMID:16710298   PMID:16786585   PMID:17070805  
PMID:17093407   PMID:17107999   PMID:17296600   PMID:17428788   PMID:17620408   PMID:17931718   PMID:17935356   PMID:18037880   PMID:18039844   PMID:18076574   PMID:18287559   PMID:18311137  
PMID:18316406   PMID:18339675   PMID:18493325   PMID:18650381   PMID:18799693   PMID:18848501   PMID:19170609   PMID:19369945   PMID:19412891   PMID:19515240   PMID:19521500   PMID:19544461  
PMID:19755104   PMID:20059953   PMID:20161715   PMID:20237291   PMID:20351251   PMID:20362541   PMID:20471950   PMID:20573702   PMID:20808772   PMID:21220025   PMID:21402785   PMID:21530438  
PMID:21589869   PMID:21873635   PMID:22083510   PMID:22269950   PMID:22305566   PMID:22325148   PMID:22325351   PMID:22496869   PMID:22499591   PMID:22562112   PMID:22609416   PMID:22713603  
PMID:22770845   PMID:22844243   PMID:22872859   PMID:23027973   PMID:23207902   PMID:23271347   PMID:23395003   PMID:23486062   PMID:23604909   PMID:23727134   PMID:23892456   PMID:24034696  
PMID:24055057   PMID:24070375   PMID:24091011   PMID:24183668   PMID:24374176   PMID:24457600   PMID:24497168   PMID:24856970   PMID:24980959   PMID:24999238   PMID:25344075   PMID:25463925  
PMID:25519132   PMID:25703348   PMID:26206133   PMID:26323060   PMID:26385961   PMID:26450788   PMID:26526724   PMID:26674308   PMID:26711264   PMID:26711500   PMID:27730210   PMID:27913604  
PMID:27930960   PMID:28111200   PMID:28584103   PMID:28596365   PMID:28855339   PMID:28900001   PMID:28924034   PMID:29242538   PMID:29371181   PMID:29727681   PMID:29874594   PMID:30186101  
PMID:30190278   PMID:30428357   PMID:30562514   PMID:30567998   PMID:30709709   PMID:30954952   PMID:31029541   PMID:31043422   PMID:31077711   PMID:31269445   PMID:31598710   PMID:31837995  
PMID:32571933   PMID:33177537   PMID:33602871   PMID:34321999   PMID:34473941   PMID:34637754   PMID:34994686   PMID:35121884   PMID:35390228   PMID:35640597   PMID:36443290   PMID:36635505  
PMID:37158107   PMID:37196079   PMID:37542070   PMID:37838801  


Genomics

Comparative Map Data
Rnf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391151,345,159 - 151,376,562 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1151,333,755 - 151,376,706 (-)EnsemblGRCm39 Ensembl
GRCm381151,469,398 - 151,500,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1151,458,004 - 151,500,955 (-)EnsemblGRCm38mm10GRCm38
MGSCv371153,316,536 - 153,347,953 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,231,624 - 153,263,041 (-)NCBIMGSCv36mm8
Celera1153,898,457 - 153,929,917 (-)NCBICelera
Cytogenetic Map1G1NCBI
cM Map164.15NCBI
RNF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381185,045,558 - 185,102,603 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1185,045,497 - 185,102,603 (+)EnsemblGRCh38hg38GRCh38
GRCh371185,014,690 - 185,071,735 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361183,281,174 - 183,338,363 (+)NCBINCBI36Build 36hg18NCBI36
Build 341181,746,207 - 181,803,397NCBI
Celera1158,125,254 - 158,182,437 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1156,249,794 - 156,306,846 (+)NCBIHuRef
CHM1_11186,434,264 - 186,493,430 (+)NCBICHM1_1
T2T-CHM13v2.01184,402,444 - 184,459,513 (+)NCBIT2T-CHM13v2.0
Rnf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81366,103,943 - 66,136,038 (-)NCBIGRCr8
mRatBN7.21363,553,964 - 63,584,047 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1363,554,862 - 63,583,099 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1366,173,599 - 66,202,587 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01367,438,219 - 67,467,208 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01364,701,587 - 64,730,534 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01368,829,714 - 68,859,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1368,830,620 - 68,858,809 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01373,791,946 - 73,821,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41366,345,663 - 66,373,826 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11366,359,742 - 66,387,906 (-)NCBI
Celera1363,485,726 - 63,513,888 (-)NCBICelera
Cytogenetic Map13q21NCBI
Rnf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540623,672,947 - 23,725,253 (+)NCBIChiLan1.0ChiLan1.0
RNF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2164,620,643 - 64,679,042 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,304,249 - 64,362,614 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01160,568,438 - 160,626,783 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,721,554 - 164,779,420 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,721,458 - 164,779,420 (+)Ensemblpanpan1.1panPan2
RNF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1718,240,672 - 18,283,091 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl718,236,115 - 18,281,387 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha717,818,956 - 17,868,157 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0717,967,438 - 18,016,584 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl717,967,947 - 18,014,756 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1717,876,830 - 17,926,016 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0717,984,666 - 18,033,949 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0718,115,806 - 18,164,938 (+)NCBIUU_Cfam_GSD_1.0
Rnf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934487,222,673 - 87,263,262 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364815,070,578 - 5,110,068 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364815,070,578 - 5,110,087 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9126,172,301 - 126,287,603 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19126,172,637 - 126,284,567 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29138,670,468 - 138,730,404 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12544,289,662 - 44,345,168 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2544,291,576 - 44,345,236 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605545,500,165 - 45,555,796 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248148,470,818 - 8,516,252 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf2
1536 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:453
Count of miRNA genes:321
Interacting mature miRNAs:352
Transcripts:ENSMUST00000076110
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139602037173602216Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141095010175095156Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
14746980Manh50_mmandible shape 50 (mouse)1134131564168131564Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147219390181219390Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142489543176489734Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141233173175233272Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139602037173602216Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139602037173602216Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145077630179077630Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147125258182873798Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147219390181219390Mouse
1301135Pas8_mpulmonary adenoma susceptibility 8 (mouse)Not determined1147125258158233272Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150756737184756922Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150193673188359312Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139602037173602216Mouse
13452392Ity3a_mimmunity to S. typhimurium 3a (mouse)1149028612154228616Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150193673188359312Mouse
1301818Ap1q_malcohol preference 1 QTL (mouse)Not determined1146908199167586222Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1135877901169878015Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139602037173602216Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150193673188359312Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9147875502181875616Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139602037173602216Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135794822169795012Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141233173175233272Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144531347178531592Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139602037173602216Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141233173175233272Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145145207179145325Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143284665177284803Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139452188173452308Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139602037173602216Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147125258188983224Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1147875502181875616Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131156308165139464Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144449142178449142Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
1357567Nidd3k_mNidd3 on KK-A<y> (mouse)Not determined7147125258169038913Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136209950170210094Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141233173175233272Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
12903996Cfq5_mconditioned fear QTL 5 (mouse)1150606337159307464Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151186243185186402Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129130858163130993Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147125258171632257Mouse

Markers in Region
RH136542  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381151,470,923 - 151,471,121UniSTSGRCm38
MGSCv371153,318,053 - 153,318,251UniSTSGRCm37
Celera1153,899,978 - 153,900,176UniSTS
Cytogenetic Map1G2UniSTS
AI326319  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381151,473,187 - 151,473,282UniSTSGRCm38
MGSCv371153,320,317 - 153,320,412UniSTSGRCm37
Celera1153,902,251 - 153,902,346UniSTS
Cytogenetic Map1G2UniSTS
Whitehead/MRC_RH11852.82UniSTS
AI450156  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381151,469,650 - 151,469,831UniSTSGRCm38
MGSCv371153,316,780 - 153,316,961UniSTSGRCm37
Celera1153,898,701 - 153,898,882UniSTS
Cytogenetic Map1G2UniSTS
Whitehead/MRC_RH11854.64UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001360844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001360845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001360847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC115060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC165946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y12783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y12880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000076110   ⟹   ENSMUSP00000075476
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1151,345,157 - 151,376,706 (-)Ensembl
GRCm38.p6 Ensembl1151,469,406 - 151,500,955 (-)Ensembl
Ensembl Acc Id: ENSMUST00000185945
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1151,347,070 - 151,349,870 (-)Ensembl
GRCm38.p6 Ensembl1151,471,319 - 151,474,119 (-)Ensembl
Ensembl Acc Id: ENSMUST00000186415   ⟹   ENSMUSP00000140594
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1151,346,873 - 151,376,584 (-)Ensembl
GRCm38.p6 Ensembl1151,471,122 - 151,500,833 (-)Ensembl
Ensembl Acc Id: ENSMUST00000187048   ⟹   ENSMUSP00000140896
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1151,345,156 - 151,376,562 (-)Ensembl
GRCm38.p6 Ensembl1151,469,405 - 151,500,811 (-)Ensembl
Ensembl Acc Id: ENSMUST00000187991   ⟹   ENSMUSP00000140299
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1151,352,652 - 151,376,545 (-)Ensembl
GRCm38.p6 Ensembl1151,476,901 - 151,500,794 (-)Ensembl
Ensembl Acc Id: ENSMUST00000188871
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1151,346,905 - 151,347,782 (-)Ensembl
GRCm38.p6 Ensembl1151,471,154 - 151,472,031 (-)Ensembl
Ensembl Acc Id: ENSMUST00000190070   ⟹   ENSMUSP00000139676
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1151,333,755 - 151,351,913 (-)Ensembl
GRCm38.p6 Ensembl1151,458,004 - 151,476,162 (-)Ensembl
RefSeq Acc Id: NM_001360844   ⟹   NP_001347773
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391151,345,159 - 151,376,562 (-)NCBI
GRCm381151,469,398 - 151,500,991 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001360845   ⟹   NP_001347774
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391151,345,159 - 151,376,562 (-)NCBI
GRCm381151,469,398 - 151,500,991 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001360847   ⟹   NP_001347776
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391151,345,159 - 151,376,562 (-)NCBI
GRCm381151,469,398 - 151,500,991 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001420940   ⟹   NP_001407869
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391151,345,159 - 151,376,562 (-)NCBI
RefSeq Acc Id: NM_001420941   ⟹   NP_001407870
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391151,345,159 - 151,376,562 (-)NCBI
RefSeq Acc Id: NM_011277   ⟹   NP_035407
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391151,345,159 - 151,376,562 (-)NCBI
GRCm381151,469,398 - 151,500,991 (-)NCBI
MGSCv371153,316,536 - 153,347,953 (-)RGD
Celera1153,898,457 - 153,929,917 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036162867   ⟹   XP_036018760
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391151,345,159 - 151,359,178 (-)NCBI
Sequence:
RefSeq Acc Id: NP_035407   ⟸   NM_011277
- UniProtKB: Q4FJV5 (UniProtKB/Swiss-Prot),   O35729 (UniProtKB/Swiss-Prot),   O35699 (UniProtKB/Swiss-Prot),   Q8C1X8 (UniProtKB/Swiss-Prot),   Q9CQJ4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001347774   ⟸   NM_001360845
- UniProtKB: Q9CQJ4 (UniProtKB/Swiss-Prot),   Q4FJV5 (UniProtKB/Swiss-Prot),   O35729 (UniProtKB/Swiss-Prot),   O35699 (UniProtKB/Swiss-Prot),   Q8C1X8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001347776   ⟸   NM_001360847
- UniProtKB: Q9CQJ4 (UniProtKB/Swiss-Prot),   Q4FJV5 (UniProtKB/Swiss-Prot),   O35729 (UniProtKB/Swiss-Prot),   O35699 (UniProtKB/Swiss-Prot),   Q8C1X8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001347773   ⟸   NM_001360844
- UniProtKB: Q9CQJ4 (UniProtKB/Swiss-Prot),   Q8C1X8 (UniProtKB/Swiss-Prot),   Q4FJV5 (UniProtKB/Swiss-Prot),   O35729 (UniProtKB/Swiss-Prot),   O35699 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000140594   ⟸   ENSMUST00000186415
Ensembl Acc Id: ENSMUSP00000139676   ⟸   ENSMUST00000190070
Ensembl Acc Id: ENSMUSP00000075476   ⟸   ENSMUST00000076110
Ensembl Acc Id: ENSMUSP00000140299   ⟸   ENSMUST00000187991
Ensembl Acc Id: ENSMUSP00000140896   ⟸   ENSMUST00000187048
RefSeq Acc Id: XP_036018760   ⟸   XM_036162867
- Peptide Label: isoform X2
- UniProtKB: Q9CQJ4 (UniProtKB/Swiss-Prot),   Q4FJV5 (UniProtKB/Swiss-Prot),   O35729 (UniProtKB/Swiss-Prot),   O35699 (UniProtKB/Swiss-Prot),   Q8C1X8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001407870   ⟸   NM_001420941
- UniProtKB: Q9CQJ4 (UniProtKB/Swiss-Prot),   Q8C1X8 (UniProtKB/Swiss-Prot),   Q4FJV5 (UniProtKB/Swiss-Prot),   O35729 (UniProtKB/Swiss-Prot),   O35699 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001407869   ⟸   NM_001420940
- UniProtKB: Q9CQJ4 (UniProtKB/Swiss-Prot),   Q8C1X8 (UniProtKB/Swiss-Prot),   Q4FJV5 (UniProtKB/Swiss-Prot),   O35729 (UniProtKB/Swiss-Prot),   O35699 (UniProtKB/Swiss-Prot)
Protein Domains
RAWUL   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CQJ4-F1-model_v2 AlphaFold Q9CQJ4 1-336 view protein structure

Promoters
RGD ID:6875224
Promoter ID:EPDNEW_M1063
Type:initiation region
Name:Rnf2_1
Description:Mus musculus ring finger protein 2 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381151,500,811 - 151,500,871EPDNEW
RGD ID:6818402
Promoter ID:MM_KWN:2407
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_011277,   UC007CYY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361153,347,839 - 153,348,339 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1101759 AgrOrtholog
Ensembl Genes ENSMUSG00000026484 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000076110 ENTREZGENE
  ENSMUST00000076110.11 UniProtKB/Swiss-Prot
  ENSMUST00000186415.7 UniProtKB/TrEMBL
  ENSMUST00000187048 ENTREZGENE
  ENSMUST00000187048.7 UniProtKB/Swiss-Prot
  ENSMUST00000187991.2 UniProtKB/TrEMBL
  ENSMUST00000190070.7 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RAWUL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING1/RING2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19821 UniProtKB/Swiss-Prot
MGD MGI:1101759 ENTREZGENE
NCBI Gene 19821 ENTREZGENE
PANTHER PTHR46076 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR46076:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RAWUL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C3HC4_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rnf2 PhenoGen
PROSITE ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WP87_MOUSE UniProtKB/TrEMBL
  A0A087WQQ3_MOUSE UniProtKB/TrEMBL
  A0A087WRE9_MOUSE UniProtKB/TrEMBL
  O35699 ENTREZGENE
  O35729 ENTREZGENE
  Q4FJV5 ENTREZGENE
  Q8C1X8 ENTREZGENE
  Q9CQJ4 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O35699 UniProtKB/Swiss-Prot
  O35729 UniProtKB/Swiss-Prot
  Q4FJV5 UniProtKB/Swiss-Prot
  Q8C1X8 UniProtKB/Swiss-Prot