MDM2 (MDM2 proto-oncogene) - Rat Genome Database

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Gene: MDM2 (MDM2 proto-oncogene) Homo sapiens
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Symbol: MDM2
Name: MDM2 proto-oncogene
RGD ID: 1313299
HGNC Page HGNC:6973
Description: Enables several functions, including disordered domain specific binding activity; p53 binding activity; and ubiquitin-like protein transferase activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator; amyloid fibril formation; and negative regulation of signal transduction by p53 class mediator. Located in centriolar satellite; cytosol; and nuclear lumen. Part of transcription repressor complex. Implicated in chronic myeloid leukemia; glioblastoma; hepatocellular carcinoma; pancreatic ductal carcinoma; and sarcoma. Biomarker of acute myeloid leukemia; biliary tract disease (multiple); ichthyosis; pancreatic ductal carcinoma; and urinary bladder cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ACTFS; double minute 2, human homolog of; double minute 2, human homolog of, p53-binding protein; E3 ubiquitin-protein ligase Mdm2; hdm2; HDM2 transcript variant MYO-1; HDM2 transcript variant MYO-18; HDM2 transcript variant MYO-20; HDM2 transcript variant MYO-24; HDM2 transcript variant MYO-25; HDM2 transcript variant MYO-26; HDM2 transcript variant MYO-32; HDM2 transcript variant MYO-4; HDMX; LSKB; MDM2 oncogene, E3 ubiquitin protein ligase; Mdm2 p53 binding protein homolog; MDM2 proto-oncogene, E3 ubiquitin protein ligase; MDM2 variant FB28; MDM2 variant FB30; Mdm2, p53 E3 ubiquitin protein ligase homolog; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; MGC5370; MGC71221; oncoprotein Mdm2; ubiquitin-protein ligase E3 Mdm2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC100130841  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381268,808,172 - 68,850,686 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1268,808,177 - 68,845,544 (+)Ensemblhg38GRCh38
GRCh371269,201,952 - 69,244,466 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361267,488,247 - 67,520,481 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341267,488,246 - 67,520,481NCBI
Celera1268,865,796 - 68,903,026 (+)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1266,252,410 - 66,289,884 (+)NCBIHuRef
CHM1_11269,170,604 - 69,207,918 (+)NCBICHM1_1
T2T-CHM13v2.01268,784,018 - 68,830,265 (+)NCBIT2T-CHM13v2.0
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-schisandrin B  (ISO)
(-)-demecolcine  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-naringenin  (EXP)
(S)-nicotine  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,10-phenanthroline  (EXP)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (EXP)
1,2-dimethylhydrazine  (ISO)
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile  (ISO)
1-nitropyrene  (EXP)
10-Hydroxycamptothecin  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (EXP)
2,2',3,3',6,6'-hexachlorobiphenyl  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-tetrachlorobiphenyl  (EXP)
2,2',4,5-tetrachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one  (EXP)
2,3,3',4,4',5,5'-Heptachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-nitrofluorene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3'-diindolylmethane  (ISO)
3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine  (EXP)
3-phenylprop-2-enal  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroperoxycyclophosphamide  (EXP)
4-hydroxyphenyl retinamide  (EXP,ISO)
5-aza-2'-deoxycytidine  (EXP)
5-azacytidine  (EXP)
5-fluorouracil  (EXP,ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (EXP)
actinomycin D  (EXP)
adefovir pivoxil  (EXP)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (EXP)
alpha-naphthoflavone  (EXP)
alvocidib  (EXP)
amifostine  (EXP)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
amphibole asbestos  (EXP)
amsacrine  (EXP)
androstane  (ISO)
antimycin A  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (EXP,ISO)
aspartame  (ISO)
atorvastatin calcium  (EXP)
atrazine  (ISO)
avobenzone  (EXP)
azoxystrobin  (EXP)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
biphenyl-4-amine  (EXP)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP)
bisphenol F  (ISO)
bortezomib  (EXP)
brassinolide  (EXP)
cadmium acetate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
camptothecin  (EXP)
cannabidiol  (EXP,ISO)
cantharidin  (EXP)
capsaicin  (EXP)
Carbadox  (ISO)
carbamazepine  (EXP)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (EXP)
chlorambucil  (EXP)
chloroacetaldehyde  (EXP)
chloroethene  (EXP)
chloroprene  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
chrysene  (ISO)
cidofovir anhydrous  (EXP)
cisplatin  (EXP,ISO)
citalopram  (ISO)
clofibrate  (ISO)
cobalt atom  (EXP)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
corn oil  (ISO)
coumarin  (EXP)
crocidolite asbestos  (ISO)
cryptolepine  (EXP)
curcumin  (EXP)
cyclosporin A  (EXP)
cylindrospermopsin  (EXP)
cyproconazole  (ISO)
DAPT  (EXP)
DDT  (ISO)
deguelin  (EXP)
DENSPM  (EXP)
deoxynivalenol  (EXP)
desferrioxamine B  (ISO)
diallyl disulfide  (ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
diclofenac  (ISO)
dieldrin  (ISO)
diepoxybutane  (EXP)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (EXP,ISO)
dioxygen  (EXP,ISO)
disodium selenite  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
eflornithine  (ISO)
ellipticine  (EXP)
endosulfan  (ISO)
epoxiconazole  (ISO)
escitalopram  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (EXP)
etoposide  (EXP,ISO)
EUK-134  (EXP)
fenbendazole  (ISO)
fenofibrate  (ISO)
fipronil  (ISO)
flavanones  (EXP)
flucytosine  (EXP)
fluoranthene  (EXP)
flutamide  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (EXP,ISO)
formononetin  (ISO)
FR900359  (EXP)
fumonisin B1  (EXP)
furan  (ISO)
furosemide  (ISO)
ganciclovir  (EXP)
geldanamycin  (EXP)
gemcitabine  (EXP)
genistein  (ISO)
gentamycin  (ISO)
glyphosate  (EXP)
gold atom  (EXP)
gold(0)  (EXP)
GSK-J4  (EXP)
GW 501516  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (EXP)
hydroxyurea  (EXP,ISO)
Icaritin  (EXP)
ifosfamide  (EXP)
Indeno[1,2,3-cd]pyrene  (EXP)
irinotecan  (EXP)
isoflurane  (ISO)
kojic acid  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
leflunomide  (EXP)
leptomycin B  (EXP)
Leucomalachite green  (ISO)
linalool  (EXP)
lipopolysaccharide  (EXP,ISO)
lupeol  (EXP)
luteolin  (ISO)
LY294002  (EXP)
mancozeb  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (EXP)
mercury dibromide  (EXP)
mercury dichloride  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methotrexate  (EXP,ISO)
methyl caffeate  (EXP)
methyl methanesulfonate  (EXP)
methylarsonic acid  (EXP,ISO)
methylmercury chloride  (EXP,ISO)
methylmercury(1+)  (ISO)
microcystin-LR  (ISO)
mifepristone  (ISO)
mitomycin C  (EXP,ISO)
mitoxantrone  (EXP)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monocrotaline  (ISO)
monosodium L-glutamate  (ISO)
motexafin gadolinium  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N-acetylsphingosine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
N-Vinyl-2-pyrrolidone  (ISO)
nefazodone  (ISO)
nickel atom  (EXP)
nickel dichloride  (EXP,ISO)
nicotinamide  (EXP)
nicotine  (EXP)
nimesulide  (ISO)
nitenpyram  (EXP)
Nodularin  (EXP)
Nutlin-3  (EXP,ISO)
O-methyleugenol  (ISO)
ochratoxin A  (EXP,ISO)
Octicizer  (EXP)
okadaic acid  (EXP)
ortho-Aminoazotoluene  (ISO)
ouabain  (EXP)
oxaliplatin  (ISO)
oxfendazole  (ISO)
p-chloromercuribenzoic acid  (EXP)
paclitaxel  (EXP)
palmatine  (EXP)
paracetamol  (EXP,ISO)
Paraoxon-methyl  (EXP)
paraquat  (EXP,ISO)
parathion  (EXP)
parathion-methyl  (EXP)
PCB138  (EXP)
PD123319  (EXP)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (EXP)
phenytoin  (ISO)
PhIP  (EXP)
phlorizin  (ISO)
phosphoramide mustard  (ISO)
picoxystrobin  (EXP)
pifithrin-alpha hydrobromide  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
platycodin D  (EXP)
poly(vinylpyrrolidone)  (EXP)
potassium bromate  (EXP)
potassium dichromate  (ISO)
pravastatin  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
promethazine  (ISO)
propanal  (EXP)
PX-866  (EXP)
quercetin  (EXP,ISO)
raloxifene  (EXP)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rotenone  (EXP)
ruthenium atom  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
SB 431542  (EXP)
selinexor  (EXP)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (EXP)
sirolimus  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sorafenib  (EXP)
staurosporine  (EXP)
succimer  (ISO)
sunitinib  (EXP)
T-2 toxin  (EXP,ISO)
tamoxifen  (EXP,ISO)
tanespimycin  (EXP)
tauroursodeoxycholic acid  (ISO)
tebufenpyrad  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
theaflavin  (ISO)
thioacetamide  (ISO)
thymoquinone  (EXP)
titanium dioxide  (EXP,ISO)
topotecan  (EXP,ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
triphenyl phosphate  (EXP,ISO)
Triptolide  (EXP,ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valdecoxib  (ISO)
valproic acid  (EXP)
vincristine  (EXP)
vorinostat  (EXP)
wortmannin  (EXP)
zidovudine  (EXP)
zinc acetate  (EXP)
zinc atom  (EXP)
zinc pyrithione  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
amyloid fibril formation  (IMP)
apoptotic process  (IDA,IEA)
atrial septum development  (IEA)
atrioventricular valve morphogenesis  (IEA)
blood vessel development  (IEA)
blood vessel remodeling  (IEA)
cardiac septum morphogenesis  (IEA)
cellular response to actinomycin D  (IDA)
cellular response to alkaloid  (IEA,ISO)
cellular response to antibiotic  (IEA,ISO)
cellular response to estrogen stimulus  (IEA,ISO)
cellular response to gamma radiation  (IDA)
cellular response to growth factor stimulus  (IEA,ISO)
cellular response to hydrogen peroxide  (IEA,ISO)
cellular response to hypoxia  (IEP)
cellular response to peptide hormone stimulus  (IEA,ISO)
cellular response to UV-C  (IEA,ISO)
cellular response to vitamin B1  (IEA,ISO)
DNA damage response, signal transduction by p53 class mediator  (IDA,IMP)
endocardial cushion morphogenesis  (IEA)
establishment of protein localization  (IDA)
fibroblast activation  (IEA,ISO)
heart development  (IEA)
heart valve development  (IEA)
negative regulation of apoptotic process  (IBA,IEA,ISO)
negative regulation of apoptotic signaling pathway  (IEA,ISO)
negative regulation of DNA damage response, signal transduction by p53 class mediator  (IDA)
negative regulation of DNA-templated transcription  (IDA,IEA,IMP,ISO)
negative regulation of gene expression  (IEA,ISO)
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator  (IMP)
negative regulation of neuron projection development  (IEA,ISO)
negative regulation of protein processing  (IEA,ISO)
negative regulation of signal transduction by p53 class mediator  (IDA,TAS)
negative regulation of transcription by RNA polymerase II  (IDA)
positive regulation of cell cycle  (IEA)
positive regulation of cell population proliferation  (TAS)
positive regulation of gene expression  (IEA,ISO)
positive regulation of mitotic cell cycle  (IBA,IEA,IMP)
positive regulation of muscle cell differentiation  (IEA)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process  (IDA)
positive regulation of protein export from nucleus  (IEA,ISO)
positive regulation of vascular associated smooth muscle cell migration  (IEA,ISO)
positive regulation of vascular associated smooth muscle cell proliferation  (IEA,ISO)
proteasome-mediated ubiquitin-dependent protein catabolic process  (IDA,TAS)
protein autoubiquitination  (IMP)
protein destabilization  (IDA,IMP)
protein localization to nucleus  (IDA)
protein polyubiquitination  (TAS)
protein sumoylation  (TAS)
protein ubiquitination  (IDA,IEA,ISO)
protein-containing complex assembly  (IDA)
protein-containing complex organization  (IEA)
proteolysis involved in protein catabolic process  (IMP)
regulation of biological quality  (IEA)
regulation of cell cycle  (IDA,IEA)
regulation of gene expression  (IEA)
regulation of heart rate  (IEA)
regulation of postsynaptic neurotransmitter receptor internalization  (IEA)
regulation of protein catabolic process  (IDA)
regulation of protein catabolic process at postsynapse, modulating synaptic transmission  (IEA)
response to antibiotic  (IEP)
response to cocaine  (IEA,ISO)
response to ether  (IEA,ISO)
response to formaldehyde  (IEA,ISO)
response to iron ion  (IEA,ISO)
response to magnesium ion  (IEA,ISO)
response to steroid hormone  (IEA,ISO)
response to toxic substance  (IEA,ISO)
response to water-immersion restraint stress  (IEA,ISO)
response to xenobiotic stimulus  (IEA,ISO)
signal transduction by p53 class mediator  (IDA)
traversing start control point of mitotic cell cycle  (IEA)
ubiquitin-dependent protein catabolic process  (IBA,IDA,IEA,IGI,IMP)
ventricular septum development  (IEA)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Age-related retinal degeneration (arrd2) in a novel mouse model due to a nonsense mutation in the Mdm1 gene. Chang B, etal., Hum Mol Genet. 2008 Dec 15;17(24):3929-41. doi: 10.1093/hmg/ddn295. Epub 2008 Sep 18.
2. Clinicopathological significance of p53 and mdm2 protein expression in human pancreatic cancer. Dong M, etal., World J Gastroenterol. 2005 Apr 14;11(14):2162-5.
3. Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis. Dongiovanni P, etal., Am J Pathol. 2010 Feb;176(2):1006-17. Epub 2009 Dec 17.
4. Long-term effects of hypothermia on neuronal cell death and the concentration of apoptotic proteins after incomplete cerebral ischemia and reperfusion in rats. Eberspacher E, etal., Acta Anaesthesiol Scand. 2005 Apr;49(4):477-87.
5. The prognostic significance of p16(INK4a)/p14(ARF) locus deletion and MDM-2 protein expression in adult acute myelogenous leukemia. Faderl S, etal., Cancer. 2000 Nov 1;89(9):1976-82.
6. Characterizing the role of MDM2 in diethylnitrosamine induced acute liver damage and development of pre-neoplastic lesions. Finnberg N, etal., Carcinogenesis. 2004 Jan;25(1):113-22. Epub 2003 Oct 10.
7. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
8. MDM2 SNP309 associates with accelerated pancreatic adenocarcinoma formation. Grochola LF, etal., Pancreas. 2010 Jan;39(1):76-80.
9. ZEB2, interacting with MDM2, contributes to the dysfuntion of brain microvascular endothelial cells and brain injury after intracerebral hemorrhage. Guo Q, etal., Cell Cycle. 2021 Sep;20(17):1692-1707. doi: 10.1080/15384101.2021.1959702. Epub 2021 Aug 2.
10. Inhibition of MDM2 attenuates neointimal hyperplasia via suppression of vascular proliferation and inflammation. Hashimoto T, etal., Cardiovasc Res. 2011 Sep 1;91(4):711-9. doi: 10.1093/cvr/cvr108. Epub 2011 Apr 14.
11. Frequent p16ink4a inactivation is an early and frequent event of intraductal papillary neoplasm of the liver arising in hepatolithiasis. Ishikawa A, etal., Hum Pathol. 2004 Dec;35(12):1505-14.
12. Differential cell cycle-regulatory protein expression in biliary tract adenocarcinoma: correlation with anatomic site, pathologic variables, and clinical outcome. Jarnagin WR, etal., J Clin Oncol. 2006 Mar 1;24(7):1152-60.
13. Experimental priapism is associated with increased oxidative stress and activation of protein degradation pathways in corporal tissue. Kanika ND, etal., Int J Impot Res. 2010 Nov-Dec;22(6):363-73. doi: 10.1038/ijir.2010.27. Epub 2010 Nov 18.
14. Nonresponsiveness of cerebral p53-MDM2 functional circuit in newborn rat pups rendered IUGR via uteroplacental insufficiency. Ke X, etal., Am J Physiol Regul Integr Comp Physiol. 2005 Apr;288(4):R1038-45. Epub 2004 Nov 24.
15. Expression of the p53 Inhibitors MDM2 and MDM4 as Outcome Predictor in Muscle-invasive Bladder Cancer. Kriegmair MC, etal., Anticancer Res. 2016 Oct;36(10):5205-5213. doi: 10.21873/anticanres.11091.
16. Modes of p53 regulation. Kruse JP and Gu W, Cell. 2009 May 15;137(4):609-22. doi: 10.1016/j.cell.2009.04.050.
17. The complexity of p53 stabilization and activation. Lavin MF and Gueven N, Cell Death Differ. 2006 Jun;13(6):941-50.
18. A molecular basis for the efficacy of magnesium treatment following traumatic brain injury in rats. Lee JS, etal., J Neurotrauma. 2004 May;21(5):549-61.
19. Up-regulation of Smurf1 after spinal cord injury in adult rats. Li D, etal., J Mol Histol. 2013 Aug;44(4):381-90. doi: 10.1007/s10735-013-9499-2. Epub 2013 Apr 18.
20. REGgamma deficiency promotes premature aging via the casein kinase 1 pathway. Li L, etal., Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11005-10. doi: 10.1073/pnas.1308497110. Epub 2013 Jun 13.
21. Molecular pathways: targeting Mdm2 and Mdm4 in cancer therapy. Li Q and Lozano G, Clin Cancer Res. 2013 Jan 1;19(1):34-41. doi: 10.1158/1078-0432.CCR-12-0053. Epub 2012 Dec 21.
22. MDM2 promoter polymorphism and p53 codon 72 polymorphism in chronic myeloid leukemia: the association between MDM2 promoter genotype and disease susceptibility, age of onset, and blast-free survival in chronic phase patients receiving imatinib. Liu YC, etal., Mol Carcinog. 2014 Dec;53(12):951-9. doi: 10.1002/mc.22061. Epub 2013 Jul 2.
23. Over-expression of PUMA correlates with the apoptosis of spinal cord cells in rat neuropathic intermittent claudication model. Ma B, etal., PLoS One. 2013 May 2;8(5):e56580. doi: 10.1371/journal.pone.0056580. Print 2013.
24. Lack of association between MDM2 SNP309 and TP53 Arg72Pro polymorphisms with clinical outcomes in myelodysplastic syndrome. Machado-Neto JA, etal., Neoplasma. 2012;59(5):530-5. doi: 10.4149/neo_2012_068.
25. p53 down-regulation: a new molecular mechanism involved in ischaemic preconditioning. Mocanu MM and Yellon DM, FEBS Lett. 2003 Dec 4;555(2):302-6.
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PMID:32856486   PMID:32874188   PMID:32880469   PMID:32894144   PMID:32901886   PMID:32904724   PMID:32910383   PMID:32929379   PMID:32951271   PMID:32985545   PMID:32994424   PMID:33020477  
PMID:33061576   PMID:33061808   PMID:33067207   PMID:33069768   PMID:33071125   PMID:33109563   PMID:33144356   PMID:33173438   PMID:33185004   PMID:33262524   PMID:33277368   PMID:33277871  
PMID:33332287   PMID:33355139   PMID:33396576   PMID:33450248   PMID:33495326   PMID:33503543   PMID:33579943   PMID:33645339   PMID:33649538   PMID:33650658   PMID:33660414   PMID:33691908  
PMID:33727672   PMID:33760190   PMID:33765973   PMID:33767425   PMID:33788740   PMID:33801773   PMID:33806062   PMID:33811963   PMID:33844281   PMID:33845483   PMID:33866408   PMID:33870698  
PMID:33889569   PMID:33903120   PMID:33930714   PMID:33955525   PMID:33961781   PMID:33985974   PMID:34017077   PMID:34032749   PMID:34040386   PMID:34048709   PMID:34077778   PMID:34099490  
PMID:34111705   PMID:34114479   PMID:34117220   PMID:34153655   PMID:34166715   PMID:34179958   PMID:34185411   PMID:34230221   PMID:34257081   PMID:34257372   PMID:34272277   PMID:34298892  
PMID:34312479   PMID:34349018   PMID:34362424   PMID:34396583   PMID:34408321   PMID:34481841   PMID:34502494   PMID:34551723   PMID:34562520   PMID:34591612   PMID:34591642   PMID:34592889  
PMID:34615546   PMID:34634443   PMID:34650049   PMID:34688145   PMID:34695137   PMID:34716260   PMID:34799561   PMID:34853296   PMID:34857952   PMID:34883204   PMID:34900978   PMID:34916375  
PMID:34927257   PMID:34954226   PMID:34975328   PMID:34986184   PMID:34992144   PMID:35025136   PMID:35030630   PMID:35044719   PMID:35053170   PMID:35066205   PMID:35073964   PMID:35136024  
PMID:35140242   PMID:35150860   PMID:35165289   PMID:35179215   PMID:35201567   PMID:35205710   PMID:35213076   PMID:35249280   PMID:35253629   PMID:35371302   PMID:35372071   PMID:35387975  
PMID:35468874   PMID:35489754   PMID:35505093   PMID:35512704   PMID:35513074   PMID:35524581   PMID:35546651   PMID:35585048   PMID:35628480   PMID:35649362   PMID:35671810   PMID:35672379  
PMID:35674210   PMID:35710596   PMID:35714490   PMID:35859155   PMID:35896951   PMID:35901340   PMID:35927984   PMID:35944929   PMID:35960313   PMID:35992795   PMID:35995868   PMID:35996826  
PMID:36042202   PMID:36050601   PMID:36114200   PMID:36396725   PMID:36503900   PMID:36513218   PMID:36515454   PMID:36521007   PMID:36525936   PMID:36528911   PMID:36546586   PMID:36578176  
PMID:36612117   PMID:36741966   PMID:36811957   PMID:36812228   PMID:36831540   PMID:36837574   PMID:36865087   PMID:36942988   PMID:36952348   PMID:37005481   PMID:37018978   PMID:37087976  
PMID:37119456   PMID:37132262   PMID:37139431   PMID:37217797   PMID:37217945   PMID:37219487   PMID:37228401   PMID:37257061   PMID:37279970   PMID:37353565   PMID:37353627   PMID:37373182  
PMID:37379210   PMID:37382239   PMID:37409874   PMID:37438558   PMID:37454155   PMID:37480689   PMID:37532224   PMID:37537694   PMID:37700392   PMID:37804415   PMID:37805657   PMID:37821635  
PMID:37981069   PMID:38104352   PMID:38134636   PMID:38159247   PMID:38200609   PMID:38263255   PMID:38396916   PMID:38519029   PMID:38580884   PMID:38708906   PMID:38924101   PMID:39047034  
PMID:39079530   PMID:39134014   PMID:39199272   PMID:39417407  


Genomics

Comparative Map Data
MDM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381268,808,172 - 68,850,686 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1268,808,177 - 68,845,544 (+)Ensemblhg38GRCh38
GRCh371269,201,952 - 69,244,466 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361267,488,247 - 67,520,481 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341267,488,246 - 67,520,481NCBI
Celera1268,865,796 - 68,903,026 (+)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1266,252,410 - 66,289,884 (+)NCBIHuRef
CHM1_11269,170,604 - 69,207,918 (+)NCBICHM1_1
T2T-CHM13v2.01268,784,018 - 68,830,265 (+)NCBIT2T-CHM13v2.0
Mdm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910117,524,780 - 117,546,663 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10117,524,780 - 117,546,663 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3810117,688,875 - 117,710,758 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10117,688,875 - 117,710,758 (-)Ensemblmm10GRCm38
MGSCv3710117,125,961 - 117,147,772 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610117,091,898 - 117,113,709 (-)NCBIMGSCv36mm8
Celera10119,626,758 - 119,648,336 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1066.32NCBI
Mdm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8755,176,558 - 55,201,757 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl755,176,560 - 55,200,791 (-)EnsemblGRCr8
mRatBN7.2753,290,660 - 53,315,205 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl753,290,664 - 53,314,915 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx755,197,377 - 55,221,597 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0757,400,491 - 57,424,715 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0757,178,368 - 57,202,590 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0760,719,060 - 60,743,618 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl760,719,066 - 60,743,328 (-)Ensemblrn6Rnor6.0
Rnor_5.0760,719,023 - 60,743,581 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4756,996,694 - 57,020,926 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera750,062,029 - 50,086,121 (-)NCBICelera
RGSC_v3.1757,018,654 - 57,054,110 (-)NCBI
Cytogenetic Map7q22NCBI
Mdm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545815,263,739 - 15,286,808 (+)Ensembl
ChiLan1.0NW_00495545815,264,028 - 15,287,290 (+)NCBIChiLan1.0ChiLan1.0
MDM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21076,824,907 - 76,859,369 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11276,824,089 - 76,858,786 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01266,322,340 - 66,357,010 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11269,102,083 - 69,133,278 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1269,102,084 - 69,133,278 (+)EnsemblpanPan2panpan1.1
MDM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11010,936,288 - 10,963,118 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1010,893,719 - 10,962,596 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1010,869,091 - 10,894,634 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01011,060,051 - 11,086,867 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1011,016,172 - 11,087,383 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11010,928,429 - 10,953,972 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01011,174,449 - 11,199,967 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01011,296,600 - 11,322,142 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mdm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494547,377,991 - 47,400,191 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365456,710,171 - 6,734,522 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365456,709,903 - 6,732,334 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MDM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl533,105,759 - 33,137,739 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1533,105,717 - 33,137,602 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2535,889,682 - 35,921,569 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MDM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11164,434,203 - 64,465,490 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1164,434,261 - 64,469,890 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037181,237,754 - 181,268,657 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in MDM2
181 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_002392.6(MDM2):c.14+309T>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV000014918]|not provided [RCV004707852] Chr12:68808800 [GRCh38]
Chr12:69202580 [GRCh37]
Chr12:12q15		 risk factor|benign
GRCh38/hg38 12q14.2-15(chr12:64368308-69123358)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052815]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052815]|See cases [RCV000052815] Chr12:64368308..69123358 [GRCh38]
Chr12:64762088..69517138 [GRCh37]
Chr12:63048355..67803405 [NCBI36]
Chr12:12q14.2-15		 pathogenic
GRCh38/hg38 12q14.3-15(chr12:65958499-69057308)x1 copy number loss See cases [RCV000052816] Chr12:65958499..69057308 [GRCh38]
Chr12:66352279..69451088 [GRCh37]
Chr12:64638546..67737355 [NCBI36]
Chr12:12q14.3-15		 pathogenic|likely pathogenic
GRCh38/hg38 12q15-21.2(chr12:68011417-75383054)x1 copy number loss See cases [RCV000135587] Chr12:68011417..75383054 [GRCh38]
Chr12:68405197..75776834 [GRCh37]
Chr12:66691464..74063101 [NCBI36]
Chr12:12q15-21.2		 likely pathogenic|uncertain significance
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33		 pathogenic
GRCh38/hg38 12q14.3-15(chr12:65445176-71026337)x1 copy number loss See cases [RCV000142445] Chr12:65445176..71026337 [GRCh38]
Chr12:65838956..71420117 [GRCh37]
Chr12:64125223..69706384 [NCBI36]
Chr12:12q14.3-15		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic|likely pathogenic
NM_002392.6(MDM2):c.1121A>G (p.Asn374Ser) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001368105] Chr12:68839476 [GRCh38]
Chr12:69233256 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.631A>C (p.Ile211Leu) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV000531653]|not specified [RCV004024212] Chr12:68828878 [GRCh38]
Chr12:69222658 [GRCh37]
Chr12:12q15		 uncertain significance
GRCh37/hg19 12q14.1-15(chr12:59495114-70574966)x1 copy number loss See cases [RCV000447164] Chr12:59495114..70574966 [GRCh37]
Chr12:12q14.1-15		 pathogenic
NM_002392.6(MDM2):c.607C>T (p.Leu203=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV000553365]|MDM2-related condition [RCV004758705]|not provided [RCV004707335] Chr12:68828854 [GRCh38]
Chr12:69222634 [GRCh37]
Chr12:12q15		 benign
GRCh37/hg19 12q15(chr12:69032901-69432620)x4 copy number gain See cases [RCV000445932] Chr12:69032901..69432620 [GRCh37]
Chr12:12q15		 uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
NM_002392.6(MDM2):c.100-10C>A single nucleotide variant Accelerated tumor formation, susceptibility to [RCV000538596]|not provided [RCV004708941] Chr12:68813544 [GRCh38]
Chr12:69207324 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.565C>T (p.Arg189Cys) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV000649880] Chr12:68828812 [GRCh38]
Chr12:69222592 [GRCh37]
Chr12:12q15		 uncertain significance
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
NM_002392.6(MDM2):c.14+55C>T single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001520940]|not provided [RCV004705792] Chr12:68808546 [GRCh38]
Chr12:69202326 [GRCh37]
Chr12:12q15		 benign|likely benign
NM_002392.6(MDM2):c.1492T>C (p.Ter498Gln) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV004813145]|Lessel-kubisch syndrome [RCV000856714] Chr12:68839847 [GRCh38]
Chr12:69233627 [GRCh37]
Chr12:12q15		 pathogenic|likely pathogenic
NM_002392.6(MDM2):c.524-3C>T single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001400522] Chr12:68828768 [GRCh38]
Chr12:69222548 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.44C>T (p.Pro15Leu) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001061986]|Accelerated tumor formation, susceptibility to [RCV005005022]|Lessel-kubisch syndrome [RCV005394707] Chr12:68809237 [GRCh38]
Chr12:69203017 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1202C>G (p.Ser401Cys) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001242918] Chr12:68839557 [GRCh38]
Chr12:69233337 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.918T>C (p.Ala306=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001239900] Chr12:68836749 [GRCh38]
Chr12:69230529 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.999G>T (p.Glu333Asp) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003105209] Chr12:68839354 [GRCh38]
Chr12:69233134 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.961C>T (p.Leu321Phe) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001211000] Chr12:68839316 [GRCh38]
Chr12:69233096 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.995G>A (p.Arg332His) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001060294]|Accelerated tumor formation, susceptibility to [RCV005005020] Chr12:68839350 [GRCh38]
Chr12:69233130 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.955C>A (p.Pro319Thr) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001219017] Chr12:68839310 [GRCh38]
Chr12:69233090 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1241A>T (p.Gln414Leu) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001217018] Chr12:68839596 [GRCh38]
Chr12:69233376 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1446A>G (p.Pro482=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001205406] Chr12:68839801 [GRCh38]
Chr12:69233581 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.683C>T (p.Pro228Leu) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001055702] Chr12:68828930 [GRCh38]
Chr12:69222710 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.309G>A (p.Arg103=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001247427] Chr12:68820325 [GRCh38]
Chr12:69214105 [GRCh37]
Chr12:12q15		 uncertain significance
GRCh37/hg19 12q15(chr12:68572386-70833868)x1 copy number loss not provided [RCV001259617] Chr12:68572386..70833868 [GRCh37]
Chr12:12q15		 pathogenic
NM_002392.6(MDM2):c.350A>G (p.Asn117Ser) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001350990]|not specified [RCV004036641] Chr12:68820366 [GRCh38]
Chr12:69214146 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.560G>C (p.Arg187Thr) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001326190] Chr12:68828807 [GRCh38]
Chr12:69222587 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.450A>G (p.Glu150=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001433550] Chr12:68824578 [GRCh38]
Chr12:69218358 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1232A>G (p.Tyr411Cys) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001319458]|not specified [RCV004034971] Chr12:68839587 [GRCh38]
Chr12:69233367 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.583A>G (p.Ile195Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001297108] Chr12:68828830 [GRCh38]
Chr12:69222610 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.777T>C (p.Ser259=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001450569] Chr12:68835921 [GRCh38]
Chr12:69229701 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.264A>G (p.Leu88=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001404590] Chr12:68816901 [GRCh38]
Chr12:69210681 [GRCh37]
Chr12:12q15		 likely benign
NC_000012.12:g.68808017C>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001509967] Chr12:68808017 [GRCh38]
Chr12:69201797 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.1002T>C (p.Asn334=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001471422] Chr12:68839357 [GRCh38]
Chr12:69233137 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1080A>G (p.Glu360=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001517224]|not provided [RCV004709054] Chr12:68839435 [GRCh38]
Chr12:69233215 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.724T>C (p.Leu242=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001479493] Chr12:68835868 [GRCh38]
Chr12:69229648 [GRCh37]
Chr12:12q15		 likely benign
GRCh37/hg19 12q14.3-21.1(chr12:65251705-75263379)x1 copy number loss not provided [RCV001537907] Chr12:65251705..75263379 [GRCh37]
Chr12:12q14.3-21.1		 pathogenic
NM_002392.6(MDM2):c.175-7A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001494474] Chr12:68816805 [GRCh38]
Chr12:69210585 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.366G>A (p.Ser122=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001475884] Chr12:68824370 [GRCh38]
Chr12:69218150 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.447G>A (p.Gln149=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001496590] Chr12:68824575 [GRCh38]
Chr12:69218355 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.-94A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001509968]|not provided [RCV004707634] Chr12:68808384 [GRCh38]
Chr12:69202164 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.960C>G (p.Pro320=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001455869] Chr12:68839315 [GRCh38]
Chr12:69233095 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.14+285G>C single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001518321] Chr12:68808776 [GRCh38]
Chr12:69202556 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.385A>C (p.Ser129Arg) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003011639] Chr12:68824389 [GRCh38]
Chr12:69218169 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.185A>T (p.Tyr62Phe) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001895953] Chr12:68816822 [GRCh38]
Chr12:69210602 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.536A>G (p.Asp179Gly) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002025289] Chr12:68828783 [GRCh38]
Chr12:69222563 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.226A>C (p.Lys76Gln) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001947987] Chr12:68816863 [GRCh38]
Chr12:69210643 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.85G>A (p.Glu29Lys) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001894478] Chr12:68809278 [GRCh38]
Chr12:69203058 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.91G>C (p.Glu31Gln) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001894316]|not specified [RCV004641713] Chr12:68809284 [GRCh38]
Chr12:69203064 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.971A>T (p.His324Leu) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001889387] Chr12:68839326 [GRCh38]
Chr12:69233106 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.886T>G (p.Ser296Ala) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001966673] Chr12:68836717 [GRCh38]
Chr12:69230497 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1237A>G (p.Ser413Gly) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002048016] Chr12:68839592 [GRCh38]
Chr12:69233372 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.15-2A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001888518] Chr12:68809206 [GRCh38]
Chr12:69202986 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.365C>T (p.Ser122Leu) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001959738] Chr12:68824369 [GRCh38]
Chr12:69218149 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1219A>G (p.Ser407Gly) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001957660] Chr12:68839574 [GRCh38]
Chr12:69233354 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.698_700del (p.Gly233del) deletion Accelerated tumor formation, susceptibility to [RCV001899541] Chr12:68835840..68835842 [GRCh38]
Chr12:69229620..69229622 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.46A>G (p.Thr16Ala) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002014376] Chr12:68809239 [GRCh38]
Chr12:69203019 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1242A>C (p.Gln414His) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001867545] Chr12:68839597 [GRCh38]
Chr12:69233377 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.154G>C (p.Asp52His) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001918232] Chr12:68813608 [GRCh38]
Chr12:69207388 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.818A>C (p.Glu273Ala) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002028690]|not specified [RCV004824058] Chr12:68835962 [GRCh38]
Chr12:69229742 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.523+5A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001905692]|Accelerated tumor formation, susceptibility to [RCV005006156] Chr12:68824656 [GRCh38]
Chr12:69218436 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.948A>C (p.Glu316Asp) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001957654] Chr12:68839303 [GRCh38]
Chr12:69233083 [GRCh37]
Chr12:12q15		 uncertain significance
NC_000012.11:g.(?_69202258)_(69233629_?)dup duplication Accelerated tumor formation, susceptibility to [RCV001900526] Chr12:69202258..69233629 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1289A>T (p.Glu430Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001997086] Chr12:68839644 [GRCh38]
Chr12:69233424 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.14+3A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001954751] Chr12:68808494 [GRCh38]
Chr12:69202274 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.57_59del (p.Val20del) deletion Accelerated tumor formation, susceptibility to [RCV002033358] Chr12:68809250..68809252 [GRCh38]
Chr12:69203030..69203032 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.212G>A (p.Arg71Gln) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002017467] Chr12:68816849 [GRCh38]
Chr12:69210629 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.913T>G (p.Leu305Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001959539] Chr12:68836744 [GRCh38]
Chr12:69230524 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1002T>A (p.Asn334Lys) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001881016] Chr12:68839357 [GRCh38]
Chr12:69233137 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1039A>G (p.Ile347Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV001918677] Chr12:68839394 [GRCh38]
Chr12:69233174 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.99+13del deletion Accelerated tumor formation, susceptibility to [RCV002187662] Chr12:68809305 [GRCh38]
Chr12:69203085 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.524-8A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002205727] Chr12:68828763 [GRCh38]
Chr12:69222543 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1491C>T (p.Pro497=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002125746] Chr12:68839846 [GRCh38]
Chr12:69233626 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.840+14del deletion Accelerated tumor formation, susceptibility to [RCV002208603] Chr12:68835991 [GRCh38]
Chr12:69229771 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.816A>G (p.Gln272=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002127091] Chr12:68835960 [GRCh38]
Chr12:69229740 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.175-13A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002196868] Chr12:68816799 [GRCh38]
Chr12:69210579 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.919-11T>C single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002113901] Chr12:68839263 [GRCh38]
Chr12:69233043 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.99+7_99+14del deletion Accelerated tumor formation, susceptibility to [RCV002131030] Chr12:68809297..68809304 [GRCh38]
Chr12:69203077..69203084 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.309-5A>C single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002215209] Chr12:68820320 [GRCh38]
Chr12:69214100 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.359-15T>C single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002117601] Chr12:68824348 [GRCh38]
Chr12:69218128 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.162T>C (p.Tyr54=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002102792] Chr12:68813616 [GRCh38]
Chr12:69207396 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.15-9dup duplication Accelerated tumor formation, susceptibility to [RCV002143594] Chr12:68809191..68809192 [GRCh38]
Chr12:69202971..69202972 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.15-9del deletion Accelerated tumor formation, susceptibility to [RCV002201216] Chr12:68809192 [GRCh38]
Chr12:69202972 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.918+15A>T single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002117864] Chr12:68836764 [GRCh38]
Chr12:69230544 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.1365C>T (p.Cys455=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002220921]|not provided [RCV004704707] Chr12:68839720 [GRCh38]
Chr12:69233500 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.243A>G (p.Val81=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002123721] Chr12:68816880 [GRCh38]
Chr12:69210660 [GRCh37]
Chr12:12q15		 likely benign
GRCh37/hg19 12q14.2-15(chr12:64609458-70352103)x1 copy number loss not provided [RCV002511748] Chr12:64609458..70352103 [GRCh37]
Chr12:12q14.2-15		 pathogenic
NM_002392.6(MDM2):c.372A>G (p.Ser124=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002967779] Chr12:68824376 [GRCh38]
Chr12:69218156 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.684+19G>A single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003073995] Chr12:68828950 [GRCh38]
Chr12:69222730 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.99+14T>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002794983] Chr12:68809306 [GRCh38]
Chr12:69203086 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1030A>G (p.Lys344Glu) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002839484] Chr12:68839385 [GRCh38]
Chr12:69233165 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.421C>G (p.Gln141Glu) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002615264] Chr12:68824425 [GRCh38]
Chr12:69218205 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.174+18A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002613782] Chr12:68813646 [GRCh38]
Chr12:69207426 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.403C>T (p.Leu135Phe) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002926834] Chr12:68824407 [GRCh38]
Chr12:69218187 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.398G>A (p.Cys133Tyr) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002662600] Chr12:68824402 [GRCh38]
Chr12:69218182 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.14+5T>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002923045] Chr12:68808496 [GRCh38]
Chr12:69202276 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1301C>G (p.Ser434Cys) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002691215] Chr12:68839656 [GRCh38]
Chr12:69233436 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.910T>C (p.Ser304Pro) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002619737] Chr12:68836741 [GRCh38]
Chr12:69230521 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1114A>G (p.Ile372Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002638650] Chr12:68839469 [GRCh38]
Chr12:69233249 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1011T>A (p.Pro337=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003038274] Chr12:68839366 [GRCh38]
Chr12:69233146 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.840+6dup duplication Accelerated tumor formation, susceptibility to [RCV002953174] Chr12:68835989..68835990 [GRCh38]
Chr12:69229769..69229770 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.99+12del deletion Accelerated tumor formation, susceptibility to [RCV002766660] Chr12:68809300 [GRCh38]
Chr12:69203080 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.393C>T (p.Asn131=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002625420] Chr12:68824397 [GRCh38]
Chr12:69218177 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1161A>C (p.Lys387Asn) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003085125] Chr12:68839516 [GRCh38]
Chr12:69233296 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.99+8T>C single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003083868] Chr12:68809300 [GRCh38]
Chr12:69203080 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.615G>C (p.Leu205=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003082790] Chr12:68828862 [GRCh38]
Chr12:69222642 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.175-15A>T single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002891000] Chr12:68816797 [GRCh38]
Chr12:69210577 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.359-4T>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002890240] Chr12:68824359 [GRCh38]
Chr12:69218139 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1248T>C (p.Asp416=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003084086] Chr12:68839603 [GRCh38]
Chr12:69233383 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.589C>T (p.Leu197Phe) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002626604] Chr12:68828836 [GRCh38]
Chr12:69222616 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.431T>C (p.Leu144Pro) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003089923]|not specified [RCV004073126] Chr12:68824559 [GRCh38]
Chr12:69218339 [GRCh37]
Chr12:12q15		 likely benign|uncertain significance
NM_002392.6(MDM2):c.684+20T>C single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002601719] Chr12:68828951 [GRCh38]
Chr12:69222731 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.88C>A (p.Gln30Lys) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003066042] Chr12:68809281 [GRCh38]
Chr12:69203061 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1191T>G (p.Ser397Arg) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002966470] Chr12:68839546 [GRCh38]
Chr12:69233326 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.305A>G (p.His102Arg) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003047192] Chr12:68816942 [GRCh38]
Chr12:69210722 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1190G>A (p.Ser397Asn) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002647445]|not specified [RCV004070702] Chr12:68839545 [GRCh38]
Chr12:69233325 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.841-16G>T single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002876942] Chr12:68836656 [GRCh38]
Chr12:69230436 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.359-8TC[2] microsatellite Accelerated tumor formation, susceptibility to [RCV002937705] Chr12:68824355..68824356 [GRCh38]
Chr12:69218135..69218136 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.613C>G (p.Leu205Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003088284] Chr12:68828860 [GRCh38]
Chr12:69222640 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1304G>A (p.Ser435Asn) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002938109] Chr12:68839659 [GRCh38]
Chr12:69233439 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.919G>A (p.Asp307Asn) single nucleotide variant not specified [RCV004163554] Chr12:68839274 [GRCh38]
Chr12:69233054 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1079A>G (p.Glu360Gly) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002814719] Chr12:68839434 [GRCh38]
Chr12:69233214 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1202C>T (p.Ser401Phe) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003051470] Chr12:68839557 [GRCh38]
Chr12:69233337 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.234A>G (p.Gln78=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003073288] Chr12:68816871 [GRCh38]
Chr12:69210651 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.694G>T (p.Ala232Ser) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002606216] Chr12:68835838 [GRCh38]
Chr12:69229618 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.643A>G (p.Arg215Gly) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002943900] Chr12:68828890 [GRCh38]
Chr12:69222670 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.99+17C>T single nucleotide variant Accelerated tumor formation, susceptibility to [RCV002582205] Chr12:68809309 [GRCh38]
Chr12:69203089 [GRCh37]
Chr12:12q15		 likely benign
GRCh37/hg19 12q14.1-15(chr12:61755618-70035424)x1 copy number loss not provided [RCV003483154] Chr12:61755618..70035424 [GRCh37]
Chr12:12q14.1-15		 pathogenic
NM_002392.6(MDM2):c.175-18A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003630806] Chr12:68816794 [GRCh38]
Chr12:69210574 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.582T>A (p.Ser194Arg) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003630830] Chr12:68828829 [GRCh38]
Chr12:69222609 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.792T>C (p.Asp264=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003515551] Chr12:68835936 [GRCh38]
Chr12:69229716 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.309-5A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003630856] Chr12:68820320 [GRCh38]
Chr12:69214100 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.524-18T>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003630763] Chr12:68828753 [GRCh38]
Chr12:69222533 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1485T>C (p.Tyr495=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003514246] Chr12:68839840 [GRCh38]
Chr12:69233620 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.56C>T (p.Ala19Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003630629]|not specified [RCV004371758] Chr12:68809249 [GRCh38]
Chr12:69203029 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.524-2A>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003630764] Chr12:68828769 [GRCh38]
Chr12:69222549 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.980G>C (p.Arg327Thr) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003630888] Chr12:68839335 [GRCh38]
Chr12:69233115 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.279C>T (p.Gly93=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003630893] Chr12:68816916 [GRCh38]
Chr12:69210696 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.156C>T (p.Asp52=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003516259] Chr12:68813610 [GRCh38]
Chr12:69207390 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.672G>A (p.Thr224=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003629487] Chr12:68828919 [GRCh38]
Chr12:69222699 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1309C>T (p.Pro437Ser) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003514074] Chr12:68839664 [GRCh38]
Chr12:69233444 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1150A>T (p.Asn384Tyr) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003515760] Chr12:68839505 [GRCh38]
Chr12:69233285 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.50A>G (p.Asp17Gly) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003629745] Chr12:68809243 [GRCh38]
Chr12:69203023 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.15-11T>C single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003629810] Chr12:68809197 [GRCh38]
Chr12:69202977 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1103G>A (p.Cys368Tyr) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003630359] Chr12:68839458 [GRCh38]
Chr12:69233238 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.864G>A (p.Gln288=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003515708] Chr12:68836695 [GRCh38]
Chr12:69230475 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.858G>T (p.Val286=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003515081] Chr12:68836689 [GRCh38]
Chr12:69230469 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.783C>T (p.Asp261=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003629300] Chr12:68835927 [GRCh38]
Chr12:69229707 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.992T>G (p.Leu331Arg) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003516268] Chr12:68839347 [GRCh38]
Chr12:69233127 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1284_1287del (p.Glu429fs) deletion Accelerated tumor formation, susceptibility to [RCV003630079] Chr12:68839637..68839640 [GRCh38]
Chr12:69233417..69233420 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.443T>C (p.Leu148Pro) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003629829] Chr12:68824571 [GRCh38]
Chr12:69218351 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1368T>C (p.Ile456=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003629652] Chr12:68839723 [GRCh38]
Chr12:69233503 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1179A>G (p.Gln393=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003628638] Chr12:68839534 [GRCh38]
Chr12:69233314 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.178C>G (p.Leu60Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003629790] Chr12:68816815 [GRCh38]
Chr12:69210595 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.685-20A>T single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003513932] Chr12:68835809 [GRCh38]
Chr12:69229589 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.685-18A>T single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003513933] Chr12:68835811 [GRCh38]
Chr12:69229591 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.377C>T (p.Thr126Ile) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003513998] Chr12:68824381 [GRCh38]
Chr12:69218161 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1405A>T (p.Thr469Ser) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003514041] Chr12:68839760 [GRCh38]
Chr12:69233540 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.815A>G (p.Gln272Arg) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003631020] Chr12:68835959 [GRCh38]
Chr12:69229739 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.100-5T>G single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003835078] Chr12:68813549 [GRCh38]
Chr12:69207329 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.652A>G (p.Ser218Gly) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003871275] Chr12:68828899 [GRCh38]
Chr12:69222679 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.685-3del deletion Accelerated tumor formation, susceptibility to [RCV003842289] Chr12:68835823 [GRCh38]
Chr12:69229603 [GRCh37]
Chr12:12q15		 benign
NM_002392.6(MDM2):c.840+14T>C single nucleotide variant Accelerated tumor formation, susceptibility to [RCV003863417] Chr12:68835998 [GRCh38]
Chr12:69229778 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.865G>A (p.Ala289Thr) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005006389]|Accelerated tumor formation, susceptibility to [RCV005104542]|not specified [RCV004421472] Chr12:68836696 [GRCh38]
Chr12:69230476 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.14+19G>A single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005011565] Chr12:68808510 [GRCh38]
Chr12:69202290 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.28A>C (p.Thr10Pro) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005011566] Chr12:68809221 [GRCh38]
Chr12:69203001 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.598G>A (p.Asp200Asn) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005011567] Chr12:68828845 [GRCh38]
Chr12:69222625 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1151A>G (p.Asn384Ser) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005011568] Chr12:68839506 [GRCh38]
Chr12:69233286 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1073A>C (p.Gln358Pro) single nucleotide variant not specified [RCV004824112] Chr12:68839428 [GRCh38]
Chr12:69233208 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.568C>T (p.His190Tyr) single nucleotide variant not specified [RCV004828101] Chr12:68828815 [GRCh38]
Chr12:69222595 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.74T>C (p.Ile25Thr) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005004987] Chr12:68809267 [GRCh38]
Chr12:69203047 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.301G>C (p.Glu101Gln) single nucleotide variant not specified [RCV004828098] Chr12:68816938 [GRCh38]
Chr12:69210718 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.821T>C (p.Leu274Pro) single nucleotide variant not specified [RCV004828099] Chr12:68835965 [GRCh38]
Chr12:69229745 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.544T>C (p.Ser182Pro) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005004988] Chr12:68828791 [GRCh38]
Chr12:69222571 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1022G>A (p.Gly341Glu) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005107115]|not specified [RCV005379718] Chr12:68839377 [GRCh38]
Chr12:69233157 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.780C>T (p.Leu260=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005170280] Chr12:68835924 [GRCh38]
Chr12:69229704 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.378A>C (p.Thr126=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005187207] Chr12:68824382 [GRCh38]
Chr12:69218162 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.1061A>G (p.Glu354Gly) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005189655] Chr12:68839416 [GRCh38]
Chr12:69233196 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.32A>G (p.Asn11Ser) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005070771] Chr12:68809225 [GRCh38]
Chr12:69203005 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.857del (p.Val286fs) deletion not specified [RCV005231828] Chr12:68836688 [GRCh38]
Chr12:69230468 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.114A>G (p.Pro38=) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005137023] Chr12:68813568 [GRCh38]
Chr12:69207348 [GRCh37]
Chr12:12q15		 likely benign
NM_002392.6(MDM2):c.80C>T (p.Ala27Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005147996] Chr12:68809273 [GRCh38]
Chr12:69203053 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.625A>G (p.Arg209Gly) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005181604] Chr12:68828872 [GRCh38]
Chr12:69222652 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.899A>T (p.Asp300Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005186588] Chr12:68836730 [GRCh38]
Chr12:69230510 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.419A>T (p.Asp140Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005190424] Chr12:68824423 [GRCh38]
Chr12:69218203 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.631A>G (p.Ile211Val) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005176588] Chr12:68828878 [GRCh38]
Chr12:69222658 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.781G>A (p.Asp261Asn) single nucleotide variant Accelerated tumor formation, susceptibility to [RCV005128621] Chr12:68835925 [GRCh38]
Chr12:69229705 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.1267G>C (p.Glu423Gln) single nucleotide variant not specified [RCV005378057] Chr12:68839622 [GRCh38]
Chr12:69233402 [GRCh37]
Chr12:12q15		 uncertain significance
NM_002392.6(MDM2):c.533C>T (p.Ser178Leu) single nucleotide variant not specified [RCV005378056] Chr12:68828780 [GRCh38]
Chr12:69222560 [GRCh37]
Chr12:12q15		 uncertain significance
miRNA Target Status (No longer updated)

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR25hsa-miR-25-3pOncomiRDBexternal_infoNANA22431589
MIR3929hsa-miR-3929Mirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248
MIR143hsa-miR-143-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI22330136
MIR143hsa-miR-143-3pOncomiRDBexternal_infoNANA22330136
MIR145hsa-miR-145-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI22330136
MIR18Bhsa-miR-18b-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23365201
MIR26Bhsa-miR-26b-5pMirtarbaseexternal_infoSequencingFunctional MTI (Weak)20371350
MIR145hsa-miR-145-5pOncomiRDBexternal_infoNANA22330136
MIR194-2hsa-miR-194-5pOncomiRDBexternal_infoNANA20951946
MIR192hsa-miR-192-5pOncomiRDBexternal_infoNANA20951946
MIR32hsa-miR-32-5pOncomiRDBexternal_infoNANA22431589
MIR504hsa-miR-504-3pTarbaseexternal_infoWesternblitNEGATIVE
MIR605hsa-miR-605-5pMirtarbaseexternal_infoReporter assay;Western blotFunctional MTI21217645
MIR605hsa-miR-605-3pTarbaseexternal_infoReporter GenePOSITIVE
MIR605hsa-miR-605-3pTarbaseexternal_infoWesternblitPOSITIVE
MIR215hsa-miR-215-5pOncomiRDBexternal_infoNANA20951946

Predicted Target Of
Summary Value
Count of predictions:14239
Count of miRNA genes:1239
Interacting mature miRNAs:1572
Transcripts:ENST00000258148, ENST00000258149, ENST00000299252, ENST00000311420, ENST00000348801, ENST00000350057, ENST00000356290, ENST00000360430, ENST00000393410, ENST00000393412, ENST00000393413, ENST00000393415, ENST00000393416, ENST00000393417, ENST00000400501, ENST00000428863, ENST00000462284, ENST00000471946, ENST00000478070, ENST00000481186, ENST00000493419, ENST00000496959, ENST00000517852, ENST00000523991, ENST00000536089, ENST00000537182, ENST00000539479, ENST00000540352, ENST00000540709, ENST00000540827, ENST00000542502, ENST00000543046, ENST00000543323, ENST00000544125, ENST00000544561, ENST00000545204, ENST00000546048
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597307610GWAS1403684_Herythrocyte count QTL GWAS1403684 (human)2e-11erythrocyte countred blood cell count (CMO:0000025)126882685668826857Human
597611774GWAS1668634_Herythrocyte count QTL GWAS1668634 (human)6e-12erythrocyte countred blood cell count (CMO:0000025)126884705068847051Human
597049698GWAS1145772_Herythrocyte count QTL GWAS1145772 (human)4e-13erythrocyte countred blood cell count (CMO:0000025)126882685668826857Human
407112193GWAS761169_Hmean corpuscular hemoglobin QTL GWAS761169 (human)2e-09erythrocyte hemoglobin amount (VT:0010953)mean corpuscular hemoglobin (CMO:0000290)126882685668826857Human
597108114GWAS1204188_Herythrocyte count QTL GWAS1204188 (human)4e-11erythrocyte countred blood cell count (CMO:0000025)126882685668826857Human
597616475GWAS1673335_Herythrocyte count QTL GWAS1673335 (human)8e-12erythrocyte countred blood cell count (CMO:0000025)126884705068847051Human
406995260GWAS644236_Hmean corpuscular hemoglobin concentration QTL GWAS644236 (human)1e-10erythrocyte hemoglobin amount (VT:0010953)mean corpuscular hemoglobin concentration (CMO:0000291)126882274168822742Human

Markers in Region
RH65828  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,237,711 - 69,237,852UniSTSGRCh37
Build 361267,523,978 - 67,524,119RGDNCBI36
Celera1268,901,533 - 68,901,674RGD
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,288,277 - 66,288,418UniSTS
HuRef1266,288,177 - 66,288,418UniSTS
GeneMap99-GB4 RH Map12289.85UniSTS
NCBI RH Map12511.5UniSTS
STS-H58373  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,238,227 - 69,238,411UniSTSGRCh37
Build 361267,524,494 - 67,524,678RGDNCBI36
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,288,793 - 66,288,977UniSTS
GeneMap99-GB4 RH Map12276.75UniSTS
NCBI RH Map12535.1UniSTS
RH11003  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,236,407 - 69,236,557UniSTSGRCh37
Build 361267,522,674 - 67,522,824RGDNCBI36
Celera1268,900,229 - 68,900,379RGD
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,286,975 - 66,287,125UniSTS
RH93271  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372104,678,892 - 104,679,096UniSTSGRCh37
GRCh371269,237,151 - 69,237,337UniSTSGRCh37
Build 362104,045,324 - 104,045,528RGDNCBI36
Celera298,880,087 - 98,880,291RGD
Celera1268,900,973 - 68,901,159UniSTS
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,287,719 - 66,287,905UniSTS
HuRef298,444,590 - 98,444,794UniSTS
GeneMap99-GB4 RH Map12280.75UniSTS
GDB:451622  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,235,652 - 69,235,751UniSTSGRCh37
GRCh371174,197,038 - 74,197,143UniSTSGRCh37
Build 361173,874,686 - 73,874,791RGDNCBI36
Celera1171,503,804 - 71,503,909RGD
Celera1268,899,474 - 68,899,573UniSTS
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,286,220 - 66,286,319UniSTS
HuRef1170,493,049 - 70,493,154UniSTS
G66928  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,232,985 - 69,233,693UniSTSGRCh37
Build 361267,519,252 - 67,519,960RGDNCBI36
Celera1268,896,810 - 68,897,518RGD
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,283,556 - 66,284,264UniSTS
G66929  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,233,528 - 69,233,736UniSTSGRCh37
Build 361267,519,795 - 67,520,003RGDNCBI36
Celera1268,897,353 - 68,897,561RGD
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,284,099 - 66,284,307UniSTS
RH45597  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,218,548 - 69,218,702UniSTSGRCh37
Build 361267,504,815 - 67,504,969RGDNCBI36
Celera1268,882,373 - 68,882,527RGD
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,269,000 - 66,269,154UniSTS
GeneMap99-GB4 RH Map12290.24UniSTS
NCBI RH Map12513.1UniSTS
PMC100259P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,202,653 - 69,202,825UniSTSGRCh37
Build 361267,488,920 - 67,489,092RGDNCBI36
Celera1268,866,478 - 68,866,650RGD
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,253,111 - 66,253,283UniSTS
PMC129072P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,202,676 - 69,202,792UniSTSGRCh37
Build 361267,488,943 - 67,489,059RGDNCBI36
Celera1268,866,501 - 68,866,617RGD
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,253,134 - 66,253,250UniSTS
MDM2_1161  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,233,582 - 69,234,271UniSTSGRCh37
Build 361267,519,849 - 67,520,538RGDNCBI36
Celera1268,897,407 - 68,898,096RGD
HuRef1266,284,153 - 66,284,842UniSTS
SGC38056  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,218,186 - 69,218,467UniSTSGRCh37
Build 361267,504,453 - 67,504,734RGDNCBI36
Celera1268,882,011 - 68,882,292RGD
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,268,638 - 66,268,919UniSTS
GeneMap99-GB4 RH Map12289.4UniSTS
Whitehead-RH Map12388.7UniSTS
NCBI RH Map12514.8UniSTS
RH45825  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,218,191 - 69,218,370UniSTSGRCh37
Build 361267,504,458 - 67,504,637RGDNCBI36
Celera1268,882,016 - 68,882,195RGD
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,268,643 - 66,268,822UniSTS
GeneMap99-GB4 RH Map12289.64UniSTS
NCBI RH Map12515.3UniSTS
D8S2278  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5p15.33UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map4q32.1UniSTS
Cytogenetic Map6q22UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map16q13UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map13q14.3UniSTS
Cytogenetic Map12q21.33UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map6q25.3UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map3p25.3-p24.1UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map2q11.2-q12.1UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map10q11UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map12q21.31UniSTS
Cytogenetic Map2q33-q34UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map7q34-q35UniSTS
Cytogenetic MapXp22.1UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map2q37UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map4q34.1UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map6q25UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map6p22UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map2p23.1UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map12p12.3UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map15q22.1UniSTS
Cytogenetic Map1p34-p33UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map17q21.1UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic Map3q25.31UniSTS
Cytogenetic Map14q22UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map5p12UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map3q26.32UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map13q11UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map3p25.1UniSTS
Cytogenetic Map14q12-q13UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map17q11.2-q12UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map11p15UniSTS
Cytogenetic Map4q31UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map7p22UniSTS
Cytogenetic Map15q15-q21.1UniSTS
Cytogenetic Map1p32-p31UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map10q25.3UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map10q22.3UniSTS
Cytogenetic Map6q27UniSTS
Cytogenetic Map11p15.3UniSTS
Cytogenetic Map4q22.1-q23UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map17q22-q23.2UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map18q22.3UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic MapXq26.1UniSTS
Cytogenetic Map4q21.21UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic MapXq13.2UniSTS
Cytogenetic Map2q32.1UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.32UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic MapXq22.3UniSTS
Cytogenetic Map3q13.13UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map10p11.23UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map11q14UniSTS
Cytogenetic Map13q33.1UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic Map1q31-q41UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map14q23UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map7q31UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map14q24.2UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map20q11.22-q11.23UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map6p24.3UniSTS
Cytogenetic Map9p24.1UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map9p21UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map3p12.1UniSTS
Cytogenetic Map1p13.2UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map12q14.3-q15UniSTS
Cytogenetic Map15q11-q13UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map3q28UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map14q24.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map14q32.2UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map2q23.3UniSTS
Cytogenetic Map7p21.1UniSTS
Cytogenetic Map8p12-p11UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map3p21.32UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map13q32.3UniSTS
Cytogenetic Map11q24UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map12q24.33UniSTS
Cytogenetic Map5q31.3UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map5q21.2UniSTS
Cytogenetic Map5q15UniSTS
Cytogenetic Map3p26.1UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map19q13.13UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map20p11UniSTS
Cytogenetic Map2p12UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map3p21.1-p14.3UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map9q33.1UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map7q35UniSTS
Cytogenetic Map16p12.3UniSTS
Cytogenetic Map2p25.3UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map3p26UniSTS
Cytogenetic Map4q32.3UniSTS
Cytogenetic Map3p14.2UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map1p36.3-p36.2UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map7p12.3UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map21q21.1UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map12q23.3UniSTS
Cytogenetic Map12q23.1UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map8q23.3UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map2q12UniSTS
Cytogenetic Map11q25UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map6p21.31UniSTS
Cytogenetic Map5p15.3UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map10q21-q22UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map17q24UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map7p13-p11.1UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map7q31.3UniSTS
Cytogenetic MapXp22.13UniSTS
Cytogenetic Map14q24UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map1p13-p12UniSTS
Cytogenetic Map4q32UniSTS
Cytogenetic Map9q22.33UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map10q21.1UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map7q21.11UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map1q12UniSTS
Cytogenetic Map3q13.1-q13.2UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map14q31UniSTS
RH44942  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,289,512 - 66,289,628UniSTS
GeneMap99-GB4 RH Map12289.11UniSTS
GDB:371587  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371269,201,977 - 69,203,047UniSTSGRCh37
Celera1268,865,802 - 68,866,872UniSTS
Cytogenetic Map12q14.3-q15UniSTS
HuRef1266,252,435 - 66,253,505UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1204 2434 2788 2247 4960 1724 2350 5 622 1950 464 2268 7292 6461 53 3725 851 1741 1616 174

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_016708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001145337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001145339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001145340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001278462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001367990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006719399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006719400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054372059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054372060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA708958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC025423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF092843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF092844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF092845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF201370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF201371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF385322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF385323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF385324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF385325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF385326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF385327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF527840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH009394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ251943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ276888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ278975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ278976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ278977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ278978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ430612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ430613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ430614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ491698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ491699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ491700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ491701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ517838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ517839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ517840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ550516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ550517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ550518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ550519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ550520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM902681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX057138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC065505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC107414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC152384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC152390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE296905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE930512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF208689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT007258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU076746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU076747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU076748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU076749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ848196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM213901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM213902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM213903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM213904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY174841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JX015392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX302151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX302152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M92424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF125237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MF125238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U28935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U33199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U33200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U33201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U33202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U33203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U39736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z12020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000258148   ⟹   ENSP00000258148
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,808,464 - 68,839,867 (+)Ensembl
Ensembl Acc Id: ENST00000258149   ⟹   ENSP00000258149
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,808,177 - 68,845,544 (+)Ensembl
Ensembl Acc Id: ENST00000299252   ⟹   ENSP00000299252
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000311420   ⟹   ENSP00000310742
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,808,273 - 68,839,867 (+)Ensembl
Ensembl Acc Id: ENST00000348801   ⟹   ENSP00000335096
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,226 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000350057   ⟹   ENSP00000266624
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000360430   ⟹   ENSP00000353611
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000393410   ⟹   ENSP00000377062
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000393412   ⟹   ENSP00000377064
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,808,191 - 68,840,216 (+)Ensembl
Ensembl Acc Id: ENST00000393413   ⟹   ENSP00000377065
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000393415   ⟹   ENSP00000377067
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,017 - 68,839,282 (+)Ensembl
Ensembl Acc Id: ENST00000393416   ⟹   ENSP00000377068
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,024 - 68,839,961 (+)Ensembl
Ensembl Acc Id: ENST00000393417   ⟹   ENSP00000429021
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,808,383 - 68,839,856 (+)Ensembl
Ensembl Acc Id: ENST00000400501
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,843,689 - 68,844,195 (+)Ensembl
Ensembl Acc Id: ENST00000428863   ⟹   ENSP00000410694
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,808,191 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000471946
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,813,602 - 68,820,414 (+)Ensembl
Ensembl Acc Id: ENST00000478070   ⟹   ENSP00000430906
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,226 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000481186   ⟹   ENSP00000431110
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,211 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000493419
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,808,282 - 68,817,018 (+)Ensembl
Ensembl Acc Id: ENST00000496959   ⟹   ENSP00000429692
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000517852   ⟹   ENSP00000430257
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000523991   ⟹   ENSP00000427828
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,017 - 68,839,314 (+)Ensembl
Ensembl Acc Id: ENST00000536089   ⟹   ENSP00000444028
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000537182   ⟹   ENSP00000443450
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000539479   ⟹   ENSP00000444430
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,002 - 68,840,807 (+)Ensembl
Ensembl Acc Id: ENST00000540352   ⟹   ENSP00000445030
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000540709
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,842,441 - 68,844,181 (+)Ensembl
Ensembl Acc Id: ENST00000542502   ⟹   ENSP00000444566
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000543046
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,824,203 - 68,824,758 (+)Ensembl
Ensembl Acc Id: ENST00000543323   ⟹   ENSP00000439238
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,017 - 68,839,314 (+)Ensembl
Ensembl Acc Id: ENST00000544125
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,843,066 - 68,844,190 (+)Ensembl
Ensembl Acc Id: ENST00000544561   ⟹   ENSP00000441841
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,961 (+)Ensembl
Ensembl Acc Id: ENST00000545204   ⟹   ENSP00000444597
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,961 (+)Ensembl
Ensembl Acc Id: ENST00000546048   ⟹   ENSP00000445222
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,849 (+)Ensembl
Ensembl Acc Id: ENST00000665020   ⟹   ENSP00000499718
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,961 (+)Ensembl
Ensembl Acc Id: ENST00000666617   ⟹   ENSP00000499763
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,961 (+)Ensembl
Ensembl Acc Id: ENST00000671567   ⟹   ENSP00000499407
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1268,809,212 - 68,839,961 (+)Ensembl
RefSeq Acc Id: NM_001145337   ⟹   NP_001138809
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,809,024 - 68,850,686 (+)NCBI
GRCh371269,201,952 - 69,239,324 (+)NCBI
HuRef1266,252,410 - 66,289,884 (+)NCBI
CHM1_11269,171,449 - 69,207,918 (+)NCBI
T2T-CHM13v2.01268,788,607 - 68,830,265 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001145339   ⟹   NP_001138811
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,808,172 - 68,845,544 (+)NCBI
GRCh371269,201,952 - 69,239,324 (+)NCBI
HuRef1266,252,410 - 66,289,884 (+)NCBI
CHM1_11269,170,604 - 69,207,918 (+)NCBI
T2T-CHM13v2.01268,787,755 - 68,825,123 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001145340   ⟹   NP_001138812
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,809,024 - 68,850,686 (+)NCBI
GRCh371269,201,952 - 69,239,324 (+)NCBI
HuRef1266,252,410 - 66,289,884 (+)NCBI
CHM1_11269,171,449 - 69,207,918 (+)NCBI
T2T-CHM13v2.01268,788,607 - 68,830,265 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001278462   ⟹   NP_001265391
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,809,024 - 68,850,686 (+)NCBI
GRCh371269,201,952 - 69,239,324 (+)NCBI
HuRef1266,252,410 - 66,289,884 (+)NCBI
CHM1_11269,171,449 - 69,207,918 (+)NCBI
T2T-CHM13v2.01268,788,607 - 68,830,265 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001367990   ⟹   NP_001354919
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,809,017 - 68,845,430 (+)NCBI
T2T-CHM13v2.01268,788,600 - 68,825,009 (+)NCBI
Sequence:
RefSeq Acc Id: NM_002392   ⟹   NP_002383
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,808,177 - 68,845,544 (+)NCBI
GRCh371269,201,952 - 69,239,324 (+)NCBI
Build 361267,488,247 - 67,520,481 (+)NCBI Archive
HuRef1266,252,410 - 66,289,884 (+)NCBI
CHM1_11269,170,604 - 69,207,918 (+)NCBI
T2T-CHM13v2.01268,787,760 - 68,825,123 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047428853   ⟹   XP_047284809
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,813,568 - 68,845,544 (+)NCBI
RefSeq Acc Id: XM_054372059   ⟹   XP_054228034
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01268,784,018 - 68,825,123 (+)NCBI
RefSeq Acc Id: XM_054372060   ⟹   XP_054228035
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01268,793,150 - 68,825,123 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001138809 (Get FASTA)   NCBI Sequence Viewer  
  NP_001138811 (Get FASTA)   NCBI Sequence Viewer  
  NP_001138812 (Get FASTA)   NCBI Sequence Viewer  
  NP_001265391 (Get FASTA)   NCBI Sequence Viewer  
  NP_001354919 (Get FASTA)   NCBI Sequence Viewer  
  NP_002383 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284809 (Get FASTA)   NCBI Sequence Viewer  
  XP_054228034 (Get FASTA)   NCBI Sequence Viewer  
  XP_054228035 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA60568 (Get FASTA)   NCBI Sequence Viewer  
  AAA75514 (Get FASTA)   NCBI Sequence Viewer  
  AAA75515 (Get FASTA)   NCBI Sequence Viewer  
  AAA75516 (Get FASTA)   NCBI Sequence Viewer  
  AAA75517 (Get FASTA)   NCBI Sequence Viewer  
  AAA75518 (Get FASTA)   NCBI Sequence Viewer  
  AAA82061 (Get FASTA)   NCBI Sequence Viewer  
  AAA82237 (Get FASTA)   NCBI Sequence Viewer  
  AAF42995 (Get FASTA)   NCBI Sequence Viewer  
  AAI52385 (Get FASTA)   NCBI Sequence Viewer  
  AAI52391 (Get FASTA)   NCBI Sequence Viewer  
  AAL13242 (Get FASTA)   NCBI Sequence Viewer  
  AAL13243 (Get FASTA)   NCBI Sequence Viewer  
  AAL13244 (Get FASTA)   NCBI Sequence Viewer  
  AAL13245 (Get FASTA)   NCBI Sequence Viewer  
  AAL13246 (Get FASTA)   NCBI Sequence Viewer  
  AAL13247 (Get FASTA)   NCBI Sequence Viewer  
  AAL40178 (Get FASTA)   NCBI Sequence Viewer  
  AAL40179 (Get FASTA)   NCBI Sequence Viewer  
  AAL40180 (Get FASTA)   NCBI Sequence Viewer  
  AAM78554 (Get FASTA)   NCBI Sequence Viewer  
  AAP35922 (Get FASTA)   NCBI Sequence Viewer  
  ABT17083 (Get FASTA)   NCBI Sequence Viewer  
  ABT17084 (Get FASTA)   NCBI Sequence Viewer  
  ABT17085 (Get FASTA)   NCBI Sequence Viewer  
  ABT17086 (Get FASTA)   NCBI Sequence Viewer  
  ACX31156 (Get FASTA)   NCBI Sequence Viewer  
  AFM80527 (Get FASTA)   NCBI Sequence Viewer  
  AFM80528 (Get FASTA)   NCBI Sequence Viewer  
  AFM80529 (Get FASTA)   NCBI Sequence Viewer  
  AFM80530 (Get FASTA)   NCBI Sequence Viewer  
  AFM80531 (Get FASTA)   NCBI Sequence Viewer  
  AFM80532 (Get FASTA)   NCBI Sequence Viewer  
  AFM80533 (Get FASTA)   NCBI Sequence Viewer  
  AFM80534 (Get FASTA)   NCBI Sequence Viewer  
  AFM80535 (Get FASTA)   NCBI Sequence Viewer  
  AFM80536 (Get FASTA)   NCBI Sequence Viewer  
  AFM80537 (Get FASTA)   NCBI Sequence Viewer  
  AFM80538 (Get FASTA)   NCBI Sequence Viewer  
  AFM80539 (Get FASTA)   NCBI Sequence Viewer  
  AFM80540 (Get FASTA)   NCBI Sequence Viewer  
  BAF83030 (Get FASTA)   NCBI Sequence Viewer  
  BAG35041 (Get FASTA)   NCBI Sequence Viewer  
  CAA78055 (Get FASTA)   NCBI Sequence Viewer  
  CAB64448 (Get FASTA)   NCBI Sequence Viewer  
  CAC07809 (Get FASTA)   NCBI Sequence Viewer  
  CAC07810 (Get FASTA)   NCBI Sequence Viewer  
  CAC07811 (Get FASTA)   NCBI Sequence Viewer  
  CAC07812 (Get FASTA)   NCBI Sequence Viewer  
  CAC22426 (Get FASTA)   NCBI Sequence Viewer  
  CAD23251 (Get FASTA)   NCBI Sequence Viewer  
  CAD23252 (Get FASTA)   NCBI Sequence Viewer  
  CAD36959 (Get FASTA)   NCBI Sequence Viewer  
  CAD36960 (Get FASTA)   NCBI Sequence Viewer  
  CAD36961 (Get FASTA)   NCBI Sequence Viewer  
  CAD36962 (Get FASTA)   NCBI Sequence Viewer  
  CAD57166 (Get FASTA)   NCBI Sequence Viewer  
  CAD57167 (Get FASTA)   NCBI Sequence Viewer  
  CAD57168 (Get FASTA)   NCBI Sequence Viewer  
  CAD79455 (Get FASTA)   NCBI Sequence Viewer  
  CAD79456 (Get FASTA)   NCBI Sequence Viewer  
  CAD79457 (Get FASTA)   NCBI Sequence Viewer  
  CAD79458 (Get FASTA)   NCBI Sequence Viewer  
  CAD79459 (Get FASTA)   NCBI Sequence Viewer  
  CAP16703 (Get FASTA)   NCBI Sequence Viewer  
  CAP16704 (Get FASTA)   NCBI Sequence Viewer  
  CAP16705 (Get FASTA)   NCBI Sequence Viewer  
  CAP16706 (Get FASTA)   NCBI Sequence Viewer  
  CAP16707 (Get FASTA)   NCBI Sequence Viewer  
  CAP16708 (Get FASTA)   NCBI Sequence Viewer  
  CAP16709 (Get FASTA)   NCBI Sequence Viewer  
  CAP16710 (Get FASTA)   NCBI Sequence Viewer  
  CAP16711 (Get FASTA)   NCBI Sequence Viewer  
  CAP16712 (Get FASTA)   NCBI Sequence Viewer  
  CAP16713 (Get FASTA)   NCBI Sequence Viewer  
  CAP16714 (Get FASTA)   NCBI Sequence Viewer  
  CAP16715 (Get FASTA)   NCBI Sequence Viewer  
  CAP16716 (Get FASTA)   NCBI Sequence Viewer  
  CAP16717 (Get FASTA)   NCBI Sequence Viewer  
  CAP16718 (Get FASTA)   NCBI Sequence Viewer  
  CAP16719 (Get FASTA)   NCBI Sequence Viewer  
  CAP16720 (Get FASTA)   NCBI Sequence Viewer  
  CAP16721 (Get FASTA)   NCBI Sequence Viewer  
  CAP16722 (Get FASTA)   NCBI Sequence Viewer  
  CAP16723 (Get FASTA)   NCBI Sequence Viewer  
  CAP16724 (Get FASTA)   NCBI Sequence Viewer  
  CAP16725 (Get FASTA)   NCBI Sequence Viewer  
  CAP16726 (Get FASTA)   NCBI Sequence Viewer  
  CAP16727 (Get FASTA)   NCBI Sequence Viewer  
  CAP16728 (Get FASTA)   NCBI Sequence Viewer  
  CAP16729 (Get FASTA)   NCBI Sequence Viewer  
  CAP16730 (Get FASTA)   NCBI Sequence Viewer  
  CAP16731 (Get FASTA)   NCBI Sequence Viewer  
  CAP16732 (Get FASTA)   NCBI Sequence Viewer  
  CAP16733 (Get FASTA)   NCBI Sequence Viewer  
  CAP16734 (Get FASTA)   NCBI Sequence Viewer  
  CAP16735 (Get FASTA)   NCBI Sequence Viewer  
  CAP16736 (Get FASTA)   NCBI Sequence Viewer  
  CAP16737 (Get FASTA)   NCBI Sequence Viewer  
  CAP16738 (Get FASTA)   NCBI Sequence Viewer  
  CAP16739 (Get FASTA)   NCBI Sequence Viewer  
  CAP16740 (Get FASTA)   NCBI Sequence Viewer  
  CAP16741 (Get FASTA)   NCBI Sequence Viewer  
  CAP16742 (Get FASTA)   NCBI Sequence Viewer  
  CAP16743 (Get FASTA)   NCBI Sequence Viewer  
  EAW97201 (Get FASTA)   NCBI Sequence Viewer  
  EAW97202 (Get FASTA)   NCBI Sequence Viewer  
  EAW97203 (Get FASTA)   NCBI Sequence Viewer  
  EAW97204 (Get FASTA)   NCBI Sequence Viewer  
  EAW97205 (Get FASTA)   NCBI Sequence Viewer  
  EAW97206 (Get FASTA)   NCBI Sequence Viewer  
  EAW97207 (Get FASTA)   NCBI Sequence Viewer  
  EAW97208 (Get FASTA)   NCBI Sequence Viewer  
  EAW97209 (Get FASTA)   NCBI Sequence Viewer  
  EAW97210 (Get FASTA)   NCBI Sequence Viewer  
  EAW97211 (Get FASTA)   NCBI Sequence Viewer  
  EAW97212 (Get FASTA)   NCBI Sequence Viewer  
  EAW97213 (Get FASTA)   NCBI Sequence Viewer  
  EAW97214 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000258148
  ENSP00000258149
  ENSP00000258149.6
  ENSP00000299252
  ENSP00000299252.4
  ENSP00000335096
  ENSP00000353611.2
  ENSP00000377065.3
  ENSP00000444430
  ENSP00000444430.2
GenBank Protein Q00987 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_002383   ⟸   NM_002392
- Peptide Label: isoform a
- UniProtKB: A8WFP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001138811   ⟸   NM_001145339
- Peptide Label: isoform h
- UniProtKB: G3XA89 (UniProtKB/TrEMBL),   A8WFP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001138809   ⟸   NM_001145337
- Peptide Label: isoform g
- UniProtKB: A0A0A8KB75 (UniProtKB/TrEMBL),   A0A0A8KB70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001265391   ⟸   NM_001278462
- Peptide Label: isoform l
- UniProtKB: A0A0C4DFR5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001138812   ⟸   NM_001145340
- Peptide Label: isoform i
- UniProtKB: A0A0C4DFR5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001354919   ⟸   NM_001367990
- Peptide Label: isoform 2
- UniProtKB: Q9UGI3 (UniProtKB/Swiss-Prot),   Q8WYJ2 (UniProtKB/Swiss-Prot),   Q8WYJ1 (UniProtKB/Swiss-Prot),   Q71TW9 (UniProtKB/Swiss-Prot),   Q53XW0 (UniProtKB/Swiss-Prot),   Q13301 (UniProtKB/Swiss-Prot),   Q13300 (UniProtKB/Swiss-Prot),   Q13299 (UniProtKB/Swiss-Prot),   Q13298 (UniProtKB/Swiss-Prot),   Q13297 (UniProtKB/Swiss-Prot),   Q13226 (UniProtKB/Swiss-Prot),   Q00987 (UniProtKB/Swiss-Prot),   A8K2S6 (UniProtKB/Swiss-Prot),   A6NL51 (UniProtKB/Swiss-Prot),   Q9UMT8 (UniProtKB/Swiss-Prot),   A8WFP2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSP00000444566   ⟸   ENST00000542502
Ensembl Acc Id: ENSP00000430906   ⟸   ENST00000478070
Ensembl Acc Id: ENSP00000430257   ⟸   ENST00000517852
Ensembl Acc Id: ENSP00000439238   ⟸   ENST00000543323
Ensembl Acc Id: ENSP00000335096   ⟸   ENST00000348801
Ensembl Acc Id: ENSP00000441841   ⟸   ENST00000544561
Ensembl Acc Id: ENSP00000444597   ⟸   ENST00000545204
Ensembl Acc Id: ENSP00000353611   ⟸   ENST00000360430
Ensembl Acc Id: ENSP00000445222   ⟸   ENST00000546048
Ensembl Acc Id: ENSP00000410694   ⟸   ENST00000428863
Ensembl Acc Id: ENSP00000258148   ⟸   ENST00000258148
Ensembl Acc Id: ENSP00000258149   ⟸   ENST00000258149
Ensembl Acc Id: ENSP00000499718   ⟸   ENST00000665020
Ensembl Acc Id: ENSP00000431110   ⟸   ENST00000481186
Ensembl Acc Id: ENSP00000299252   ⟸   ENST00000299252
Ensembl Acc Id: ENSP00000499763   ⟸   ENST00000666617
Ensembl Acc Id: ENSP00000429692   ⟸   ENST00000496959
Ensembl Acc Id: ENSP00000310742   ⟸   ENST00000311420
Ensembl Acc Id: ENSP00000266624   ⟸   ENST00000350057
Ensembl Acc Id: ENSP00000444028   ⟸   ENST00000536089
Ensembl Acc Id: ENSP00000427828   ⟸   ENST00000523991
Ensembl Acc Id: ENSP00000443450   ⟸   ENST00000537182
Ensembl Acc Id: ENSP00000444430   ⟸   ENST00000539479
Ensembl Acc Id: ENSP00000377067   ⟸   ENST00000393415
Ensembl Acc Id: ENSP00000429021   ⟸   ENST00000393417
Ensembl Acc Id: ENSP00000377068   ⟸   ENST00000393416
Ensembl Acc Id: ENSP00000377062   ⟸   ENST00000393410
Ensembl Acc Id: ENSP00000377065   ⟸   ENST00000393413
Ensembl Acc Id: ENSP00000377064   ⟸   ENST00000393412
Ensembl Acc Id: ENSP00000499407   ⟸   ENST00000671567
Ensembl Acc Id: ENSP00000445030   ⟸   ENST00000540352
RefSeq Acc Id: XP_047284809   ⟸   XM_047428853
- Peptide Label: isoform X1
- UniProtKB: J3KN53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054228034   ⟸   XM_054372059
- Peptide Label: isoform X2
- UniProtKB: A8WFP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054228035   ⟸   XM_054372060
- Peptide Label: isoform X1
- UniProtKB: J3KN53 (UniProtKB/TrEMBL)
Protein Domains
DM2   RanBP2-type   RING-type   SWIB/MDM2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q00987-F1-model_v2 AlphaFold Q00987 1-491 view protein structure

Promoters
RGD ID:6790249
Promoter ID:HG_KWN:16116
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000258148,   ENST00000311420,   ENST00000311440,   ENST00000350057,   ENST00000356290,   ENST00000358483,   ENST00000393412,   ENST00000393413,   ENST00000393416,   OTTHUMT00000286419,   OTTHUMT00000286433,   UC001SUK.1,   UC001SUL.1,   UC009ZQW.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361267,487,821 - 67,488,347 (+)MPROMDB
RGD ID:6790252
Promoter ID:HG_KWN:16117
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000299252,   OTTHUMT00000286420,   OTTHUMT00000286430,   OTTHUMT00000286431,   UC001SUM.1,   UC001SUN.2,   UC001SUO.1,   UC009ZQY.1,   UC009ZQZ.1,   UC009ZRA.1,   UC009ZRB.1,   UC009ZRC.1,   UC009ZRD.1,   UC009ZRE.1,   UC009ZRF.1,   UC009ZRG.1,   UC009ZRH.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361267,488,221 - 67,489,077 (+)MPROMDB
RGD ID:6790247
Promoter ID:HG_KWN:16118
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:OTTHUMT00000286432
Position:
Human AssemblyChrPosition (strand)Source
Build 361267,492,721 - 67,493,772 (+)MPROMDB
RGD ID:6810347
Promoter ID:HG_ACW:17741
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:MDM2.LAPR07,   MDM2.TAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 361267,503,736 - 67,504,236 (+)MPROMDB
RGD ID:7224753
Promoter ID:EPDNEW_H18123
Type:initiation region
Name:MDM2_2
Description:MDM2 proto-oncogene
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18124  EPDNEW_H18125  EPDNEW_H18126  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,808,179 - 68,808,239EPDNEW
RGD ID:7224757
Promoter ID:EPDNEW_H18124
Type:initiation region
Name:MDM2_3
Description:MDM2 proto-oncogene
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18123  EPDNEW_H18125  EPDNEW_H18126  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,808,448 - 68,808,508EPDNEW
RGD ID:7224759
Promoter ID:EPDNEW_H18125
Type:initiation region
Name:MDM2_1
Description:MDM2 proto-oncogene
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18123  EPDNEW_H18124  EPDNEW_H18126  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,809,024 - 68,809,084EPDNEW
RGD ID:7224761
Promoter ID:EPDNEW_H18126
Type:initiation region
Name:MDM2_4
Description:MDM2 proto-oncogene
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H18123  EPDNEW_H18124  EPDNEW_H18125  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381268,809,246 - 68,809,306EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6973 AgrOrtholog
COSMIC MDM2 COSMIC
Ensembl Genes ENSG00000135679 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000258148 ENTREZGENE
  ENST00000258149 ENTREZGENE
  ENST00000258149.11 UniProtKB/Swiss-Prot
  ENST00000299252 ENTREZGENE
  ENST00000299252.8 UniProtKB/Swiss-Prot
  ENST00000348801 ENTREZGENE
  ENST00000360430.6 UniProtKB/Swiss-Prot
  ENST00000393413.7 UniProtKB/Swiss-Prot
  ENST00000539479 ENTREZGENE
  ENST00000539479.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.245.10 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
  Zn-finger domain of Sec23/24 UniProtKB/Swiss-Prot
GTEx ENSG00000135679 GTEx
HGNC ID HGNC:6973 ENTREZGENE
Human Proteome Map MDM2 Human Proteome Map
InterPro Mdm2 UniProtKB/Swiss-Prot
  MDM2_mRING-HC-C2H2C4 UniProtKB/Swiss-Prot
  p53_neg-reg_MDM_2/4 UniProtKB/Swiss-Prot
  SWIB_MDM2_dom_sf UniProtKB/Swiss-Prot
  SWIB_MDM2_domain UniProtKB/Swiss-Prot
  Znf_RanBP2 UniProtKB/Swiss-Prot
  Znf_RanBP2_sf UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report hsa:4193 UniProtKB/Swiss-Prot
NCBI Gene 4193 ENTREZGENE
OMIM 164785 OMIM
PANTHER E3 UBIQUITIN-PROTEIN LIGASE MDM2 UniProtKB/Swiss-Prot
  OS05G0521000 PROTEIN UniProtKB/Swiss-Prot
Pfam SWIB UniProtKB/Swiss-Prot
  zf-C3HC4_3 UniProtKB/Swiss-Prot
  zf-RanBP UniProtKB/Swiss-Prot
PharmGKB PA30718 PharmGKB
PIRSF MDM2 UniProtKB/Swiss-Prot
  p53_MDM_2/4 UniProtKB/Swiss-Prot
PROSITE SWIB_MDM2 UniProtKB/Swiss-Prot
  ZF_RANBP2_1 UniProtKB/Swiss-Prot
  ZF_RANBP2_2 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF47592 UniProtKB/Swiss-Prot
  SSF90209 UniProtKB/Swiss-Prot
UniProt A0A0A8K972_HUMAN UniProtKB/TrEMBL
  A0A0A8K975_HUMAN UniProtKB/TrEMBL
  A0A0A8K978_HUMAN UniProtKB/TrEMBL
  A0A0A8K982_HUMAN UniProtKB/TrEMBL
  A0A0A8K986_HUMAN UniProtKB/TrEMBL
  A0A0A8K992_HUMAN UniProtKB/TrEMBL
  A0A0A8K9A1_HUMAN UniProtKB/TrEMBL
  A0A0A8K9A4_HUMAN UniProtKB/TrEMBL
  A0A0A8K9G1_HUMAN UniProtKB/TrEMBL
  A0A0A8K9G9_HUMAN UniProtKB/TrEMBL
  A0A0A8K9H4_HUMAN UniProtKB/TrEMBL
  A0A0A8K9H7_HUMAN UniProtKB/TrEMBL
  A0A0A8K9I1_HUMAN UniProtKB/TrEMBL
  A0A0A8KA03_HUMAN UniProtKB/TrEMBL
  A0A0A8KA06_HUMAN UniProtKB/TrEMBL
  A0A0A8KA17_HUMAN UniProtKB/TrEMBL
  A0A0A8KB67_HUMAN UniProtKB/TrEMBL
  A0A0A8KB70 ENTREZGENE, UniProtKB/TrEMBL
  A0A0A8KB75 ENTREZGENE, UniProtKB/TrEMBL
  A0A0A8KB78_HUMAN UniProtKB/TrEMBL
  A0A0A8KB88_HUMAN UniProtKB/TrEMBL
  A0A0A8KB92_HUMAN UniProtKB/TrEMBL
  A0A0A8KB97_HUMAN UniProtKB/TrEMBL
  A0A0A8KBA1_HUMAN UniProtKB/TrEMBL
  A0A0C4DFR5 ENTREZGENE, UniProtKB/TrEMBL
  A0A1B0GXJ6_HUMAN UniProtKB/TrEMBL
  A6NL51 ENTREZGENE
  A7UKX7_HUMAN UniProtKB/TrEMBL
  A7UKX8_HUMAN UniProtKB/TrEMBL
  A7UKX9_HUMAN UniProtKB/TrEMBL
  A7UKY0_HUMAN UniProtKB/TrEMBL
  A8K2S6 ENTREZGENE
  A8WFP2 ENTREZGENE, UniProtKB/TrEMBL
  D0EKL1_HUMAN UniProtKB/TrEMBL
  E5RHE2_HUMAN UniProtKB/TrEMBL
  E5RJQ0_HUMAN UniProtKB/TrEMBL
  E7EMW5_HUMAN UniProtKB/TrEMBL
  E7EPE2_HUMAN UniProtKB/TrEMBL
  F5GWH7_HUMAN UniProtKB/TrEMBL
  F5GZB0_HUMAN UniProtKB/TrEMBL
  F5GZC3_HUMAN UniProtKB/TrEMBL
  F5H1M7_HUMAN UniProtKB/TrEMBL
  F5H4Q8_HUMAN UniProtKB/TrEMBL
  F6UXB6_HUMAN UniProtKB/TrEMBL
  G3XA89 ENTREZGENE, UniProtKB/TrEMBL
  J3KN53 ENTREZGENE, UniProtKB/TrEMBL
  J3QST1_HUMAN UniProtKB/TrEMBL
  MDM2_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q13226 ENTREZGENE
  Q13297 ENTREZGENE
  Q13298 ENTREZGENE
  Q13299 ENTREZGENE
  Q13300 ENTREZGENE
  Q13301 ENTREZGENE
  Q53XW0 ENTREZGENE
  Q546E6_HUMAN UniProtKB/TrEMBL
  Q71TW9 ENTREZGENE
  Q8NDV9_HUMAN UniProtKB/TrEMBL
  Q8NDW0_HUMAN UniProtKB/TrEMBL
  Q8NDW1_HUMAN UniProtKB/TrEMBL
  Q8NDW2_HUMAN UniProtKB/TrEMBL
  Q8WYJ1 ENTREZGENE
  Q8WYJ2 ENTREZGENE
  Q8WYJ3_HUMAN UniProtKB/TrEMBL
  Q96DS0_HUMAN UniProtKB/TrEMBL
  Q96DS1_HUMAN UniProtKB/TrEMBL
  Q96DS2_HUMAN UniProtKB/TrEMBL
  Q96DS3_HUMAN UniProtKB/TrEMBL
  Q96DS4_HUMAN UniProtKB/TrEMBL
  Q96DS5_HUMAN UniProtKB/TrEMBL
  Q9H4C2_HUMAN UniProtKB/TrEMBL
  Q9H4C3_HUMAN UniProtKB/TrEMBL
  Q9H4C4_HUMAN UniProtKB/TrEMBL
  Q9H4C5_HUMAN UniProtKB/TrEMBL
  Q9UGI3 ENTREZGENE
  Q9UMT8 ENTREZGENE
UniProt Secondary A6NL51 UniProtKB/Swiss-Prot
  A8K2S6 UniProtKB/Swiss-Prot
  Q13226 UniProtKB/Swiss-Prot
  Q13297 UniProtKB/Swiss-Prot
  Q13298 UniProtKB/Swiss-Prot
  Q13299 UniProtKB/Swiss-Prot
  Q13300 UniProtKB/Swiss-Prot
  Q13301 UniProtKB/Swiss-Prot
  Q53XW0 UniProtKB/Swiss-Prot
  Q71TW9 UniProtKB/Swiss-Prot
  Q8WYJ1 UniProtKB/Swiss-Prot
  Q8WYJ2 UniProtKB/Swiss-Prot
  Q9UGI3 UniProtKB/Swiss-Prot
  Q9UMT8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-21 MDM2  MDM2 proto-oncogene  MDM2  MDM2 proto-oncogene, E3 ubiquitin protein ligase  Symbol and/or name change 5135510 APPROVED
2014-07-01 MDM2  MDM2 proto-oncogene, E3 ubiquitin protein ligase  MDM2  MDM2 oncogene, E3 ubiquitin protein ligase  Symbol and/or name change 5135510 APPROVED
2013-03-12 MDM2  MDM2 oncogene, E3 ubiquitin protein ligase  MDM2  Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)  Symbol and/or name change 5135510 APPROVED
2012-03-01 MDM2  Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)  MDM2  Mdm2 p53 binding protein homolog (mouse)  Symbol and/or name change 5135510 APPROVED