SLC39A6 (solute carrier family 39 member 6) - Rat Genome Database

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Gene: SLC39A6 (solute carrier family 39 member 6) Homo sapiens
Analyze
Symbol: SLC39A6
Name: solute carrier family 39 member 6
RGD ID: 1312236
HGNC Page HGNC:18607
Description: Enables zinc ion transmembrane transporter activity. Involved in several processes, including T cell receptor signaling pathway; intracellular zinc ion homeostasis; and zinc ion import across plasma membrane. Located in lamellipodium membrane and membrane raft.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: estrogen-regulated protein LIV-1; LIV-1; LIV-1 protein, estrogen regulated; LIV1; solute carrier family 39 (metal ion transporter), member 6; solute carrier family 39 (zinc transporter), member 6; zinc transporter 6; zinc transporter ZIP6; ZIP-6; ZIP6; zrt- and Irt-like protein 6; ZRT/IRT-like protein 6
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381836,108,531 - 36,129,340 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1836,108,531 - 36,129,385 (-)EnsemblGRCh38hg38GRCh38
GRCh371833,688,494 - 33,709,303 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361831,942,492 - 31,963,355 (-)NCBINCBI36Build 36hg18NCBI36
Build 341831,943,196 - 31,963,203NCBI
Celera1830,496,380 - 30,517,237 (-)NCBICelera
Cytogenetic Map18q12.2NCBI
HuRef1830,547,399 - 30,568,273 (-)NCBIHuRef
CHM1_11833,615,574 - 33,636,438 (-)NCBICHM1_1
T2T-CHM13v2.01836,300,097 - 36,320,904 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(S)-nicotine  (EXP)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (EXP)
amitrole  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (EXP)
Azoxymethane  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (ISO)
calcitriol  (EXP)
cannabidiol  (ISO)
CGP 52608  (EXP)
chromium(6+)  (EXP)
copper(II) sulfate  (EXP)
Cuprizon  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP)
enzyme inhibitor  (EXP)
ethanol  (ISO)
flutamide  (ISO)
FR900359  (EXP)
fulvestrant  (EXP)
gallium nitrate  (EXP)
geldanamycin  (EXP)
hypochlorous acid  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N-nitrosodimethylamine  (ISO)
nicotine  (EXP)
ochratoxin A  (EXP)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
raloxifene  (EXP)
SB 431542  (EXP)
serpentine asbestos  (EXP)
Soman  (ISO)
sulfadimethoxine  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
thiram  (EXP)
titanium dioxide  (ISO)
torcetrapib  (EXP)
trichloroethene  (ISO)
trichostatin A  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (EXP)
vancomycin  (ISO)
vinclozolin  (ISO)
vorinostat  (EXP)
zearalenone  (EXP)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2903103   PMID:11911440   PMID:12477932   PMID:12659941   PMID:12839489   PMID:12960427   PMID:15340161   PMID:15489334   PMID:15642354   PMID:15986450   PMID:17207965   PMID:17786585  
PMID:17825787   PMID:17959546   PMID:18272141   PMID:18330719   PMID:19066393   PMID:19336002   PMID:19581412   PMID:19724917   PMID:19852955   PMID:19887557   PMID:21422171   PMID:21873635  
PMID:22110740   PMID:22349685   PMID:22779921   PMID:22852056   PMID:23437163   PMID:23644492   PMID:23919497   PMID:24587242   PMID:25420545   PMID:25969539   PMID:26186194   PMID:26439863  
PMID:26444413   PMID:26514267   PMID:26638075   PMID:26684241   PMID:26831064   PMID:27274087   PMID:27880917   PMID:28209530   PMID:28514442   PMID:28833062   PMID:29180619   PMID:30194290  
PMID:30339739   PMID:30552163   PMID:31636012   PMID:31703635   PMID:31732153   PMID:31871319   PMID:32296183   PMID:32797246   PMID:33060197   PMID:33957083   PMID:33961781   PMID:34079125  
PMID:34186245   PMID:34394081   PMID:34453638   PMID:35063084   PMID:35271311   PMID:35696571   PMID:36610398   PMID:36976175   PMID:37435980   PMID:37499664   PMID:38070861   PMID:38117590  
PMID:38334954   PMID:38345361   PMID:38569033   PMID:39499777  


Genomics

Comparative Map Data
SLC39A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381836,108,531 - 36,129,340 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1836,108,531 - 36,129,385 (-)EnsemblGRCh38hg38GRCh38
GRCh371833,688,494 - 33,709,303 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361831,942,492 - 31,963,355 (-)NCBINCBI36Build 36hg18NCBI36
Build 341831,943,196 - 31,963,203NCBI
Celera1830,496,380 - 30,517,237 (-)NCBICelera
Cytogenetic Map18q12.2NCBI
HuRef1830,547,399 - 30,568,273 (-)NCBIHuRef
CHM1_11833,615,574 - 33,636,438 (-)NCBICHM1_1
T2T-CHM13v2.01836,300,097 - 36,320,904 (-)NCBIT2T-CHM13v2.0
Slc39a6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391824,712,938 - 24,736,874 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1824,712,938 - 24,736,874 (-)EnsemblGRCm39 Ensembl
GRCm381824,579,881 - 24,603,817 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1824,579,881 - 24,603,817 (-)EnsemblGRCm38mm10GRCm38
MGSCv371824,738,382 - 24,762,318 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361824,722,891 - 24,744,582 (-)NCBIMGSCv36mm8
Celera1825,061,823 - 25,085,732 (-)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1813.18NCBI
Slc39a6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81816,139,621 - 16,160,163 (-)NCBIGRCr8
mRatBN7.21815,864,874 - 15,885,417 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1815,864,875 - 15,885,417 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1816,052,216 - 16,072,721 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01816,834,922 - 16,855,427 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01816,123,136 - 16,143,636 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01816,523,450 - 16,543,992 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1816,522,982 - 16,543,992 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01816,277,809 - 16,303,318 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41816,353,725 - 16,374,267 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11816,380,371 - 16,400,913 (-)NCBI
Celera1815,793,993 - 15,814,535 (-)NCBICelera
Cytogenetic Map18p12NCBI
Slc39a6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540222,670,437 - 22,698,591 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540222,670,598 - 22,698,455 (-)NCBIChiLan1.0ChiLan1.0
SLC39A6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21753,504,530 - 53,525,425 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11839,197,119 - 39,218,011 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01829,361,261 - 29,382,115 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11832,919,878 - 32,940,703 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1832,919,878 - 32,940,694 (-)Ensemblpanpan1.1panPan2
SLC39A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1754,059,193 - 54,080,582 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl754,059,193 - 54,080,582 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha753,484,787 - 53,506,210 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0754,029,546 - 54,050,763 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl754,029,546 - 54,051,203 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1753,712,679 - 53,734,108 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0753,736,059 - 53,757,253 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0754,028,706 - 54,049,911 (+)NCBIUU_Cfam_GSD_1.0
Slc39a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494449,839,576 - 49,860,672 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365179,167,334 - 9,189,345 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365179,166,989 - 9,188,114 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC39A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6119,861,846 - 119,885,378 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16119,861,853 - 119,885,836 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26112,387,757 - 112,411,495 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC39A6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11844,681,718 - 44,702,741 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1844,681,508 - 44,702,754 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605019,141,804 - 19,163,079 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc39a6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477910,399,198 - 10,432,869 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477910,400,581 - 10,433,405 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC39A6
44 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 18q12.1-12.3(chr18:31655749-42564094)x3 copy number gain See cases [RCV000050773] Chr18:31655749..42564094 [GRCh38]
Chr18:29235712..40144059 [GRCh37]
Chr18:27489710..38398057 [NCBI36]
Chr18:18q12.1-12.3		 pathogenic
GRCh38/hg38 18q12.1-12.3(chr18:29444510-40403652)x1 copy number loss See cases [RCV000051090] Chr18:29444510..40403652 [GRCh38]
Chr18:27024475..37983616 [GRCh37]
Chr18:25278473..36237614 [NCBI36]
Chr18:18q12.1-12.3		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:148963-80252149)x3 copy number gain See cases [RCV000051048] Chr18:148963..80252149 [GRCh38]
Chr18:148963..78010032 [GRCh37]
Chr18:138963..76111023 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q11.1-23(chr18:20960320-80234429)x3 copy number gain See cases [RCV000052543] Chr18:20960320..80234429 [GRCh38]
Chr18:18540281..77992312 [GRCh37]
Chr18:16794279..76093303 [NCBI36]
Chr18:18q11.1-23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:53345-80209986)x3 copy number gain See cases [RCV000052501] Chr18:53345..80209986 [GRCh38]
Chr18:53345..77967869 [GRCh37]
Chr18:43345..76068860 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q11.1-23(chr18:20989762-80209986)x3 copy number gain See cases [RCV000052549] Chr18:20989762..80209986 [GRCh38]
Chr18:18569723..77967869 [GRCh37]
Chr18:16823721..76068860 [NCBI36]
Chr18:18q11.1-23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:148763-80252290)x3 copy number gain See cases [RCV000052507] Chr18:148763..80252290 [GRCh38]
Chr18:148763..78010173 [GRCh37]
Chr18:138763..76111164 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q12.1-22.1(chr18:29249202-65448117)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052563]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052563]|See cases [RCV000052563] Chr18:29249202..65448117 [GRCh38]
Chr18:26829167..63115353 [GRCh37]
Chr18:25083165..61266333 [NCBI36]
Chr18:18q12.1-22.1		 pathogenic
GRCh38/hg38 18q12.1-12.2(chr18:35097761-39379288)x3 copy number gain See cases [RCV000052567] Chr18:35097761..39379288 [GRCh38]
Chr18:32677725..36959252 [GRCh37]
Chr18:30931723..35213250 [NCBI36]
Chr18:18q12.1-12.2		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:148963-80244381)x3 copy number gain See cases [RCV000052514] Chr18:148963..80244381 [GRCh38]
Chr18:148963..78002264 [GRCh37]
Chr18:138963..76103255 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q12.1-12.3(chr18:32111530-44070219)x1 copy number loss See cases [RCV000053829] Chr18:32111530..44070219 [GRCh38]
Chr18:29691493..41650184 [GRCh37]
Chr18:27945491..39904182 [NCBI36]
Chr18:18q12.1-12.3		 pathogenic
GRCh38/hg38 18q12.1-12.3(chr18:34047118-41394354)x1 copy number loss See cases [RCV000053830] Chr18:34047118..41394354 [GRCh38]
Chr18:31627082..38974318 [GRCh37]
Chr18:29881080..37228316 [NCBI36]
Chr18:18q12.1-12.3		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:149089-80234391)x3 copy number gain See cases [RCV000134110] Chr18:149089..80234391 [GRCh38]
Chr18:149089..77992274 [GRCh37]
Chr18:139089..76093265 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q12.1-23(chr18:32123105-80252149)x3 copy number gain See cases [RCV000136890] Chr18:32123105..80252149 [GRCh38]
Chr18:29703068..78010032 [GRCh37]
Chr18:27957066..76111023 [NCBI36]
Chr18:18q12.1-23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:118760-80254946)x3 copy number gain See cases [RCV000138656] Chr18:118760..80254946 [GRCh38]
Chr18:118760..78012829 [GRCh37]
Chr18:108760..76113817 [NCBI36]
Chr18:18p11.32-q23		 pathogenic|conflicting data from submitters
GRCh38/hg38 18q12.1-12.2(chr18:33373798-37364748)x1 copy number loss See cases [RCV000138295] Chr18:33373798..37364748 [GRCh38]
Chr18:30953762..34944711 [GRCh37]
Chr18:29207760..33198709 [NCBI36]
Chr18:18q12.1-12.2		 likely pathogenic
GRCh38/hg38 18p11.32-q23(chr18:149089-80254936)x3 copy number gain See cases [RCV000139397] Chr18:149089..80254936 [GRCh38]
Chr18:149089..78012819 [GRCh37]
Chr18:139089..76113807 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:136227-80256240)x3 copy number gain See cases [RCV000142244] Chr18:136227..80256240 [GRCh38]
Chr18:136227..78014123 [GRCh37]
Chr18:126227..76115097 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18q12.2(chr18:35990843-36963685)x1 copy number loss See cases [RCV000142344] Chr18:35990843..36963685 [GRCh38]
Chr18:33570806..34543648 [GRCh37]
Chr18:31824804..32797646 [NCBI36]
Chr18:18q12.2		 uncertain significance
GRCh38/hg38 18q11.1-12.3(chr18:20941324-40360620)x3 copy number gain See cases [RCV000142226] Chr18:20941324..40360620 [GRCh38]
Chr18:18521285..37940584 [GRCh37]
Chr18:16775283..36194582 [NCBI36]
Chr18:18q11.1-12.3		 pathogenic
GRCh38/hg38 18q11.1-22.3(chr18:20962119-74691446)x3 copy number gain See cases [RCV000143057] Chr18:20962119..74691446 [GRCh38]
Chr18:18542080..72403402 [GRCh37]
Chr18:16796078..70532390 [NCBI36]
Chr18:18q11.1-22.3		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:136226-80256240)x3 copy number gain See cases [RCV000143218] Chr18:136226..80256240 [GRCh38]
Chr18:136226..78014123 [GRCh37]
Chr18:126226..76115097 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh38/hg38 18p11.32-q23(chr18:148963-80252149)x3 copy number gain See cases [RCV000148072] Chr18:148963..80252149 [GRCh38]
Chr18:148963..78010032 [GRCh37]
Chr18:138963..76111023 [NCBI36]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:163323-78005236)x3 copy number gain See cases [RCV000240130] Chr18:163323..78005236 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18q12.2(chr18:33611007-33722860)x4 copy number gain Breast ductal adenocarcinoma [RCV000207101] Chr18:33611007..33722860 [GRCh37]
Chr18:18q12.2		 uncertain significance
GRCh37/hg19 18q11.1-23(chr18:18548019-77954165)x3 copy number gain See cases [RCV000240476] Chr18:18548019..77954165 [GRCh37]
Chr18:18q11.1-23		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:136226-78014123)x3 copy number gain See cases [RCV000446047] Chr18:136226..78014123 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:163323-78005185)x3 copy number gain See cases [RCV000445851] Chr18:163323..78005185 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18q12.2-23(chr18:33417216-78014123)x3 copy number gain See cases [RCV000512081] Chr18:33417216..78014123 [GRCh37]
Chr18:18q12.2-23		 pathogenic
GRCh37/hg19 18q11.2-12.2(chr18:20069932-36887326)x1 copy number loss See cases [RCV000510691] Chr18:20069932..36887326 [GRCh37]
Chr18:18q11.2-12.2		 pathogenic
GRCh37/hg19 18p11.32-q21.1(chr18:136227-46171053)x3 copy number gain See cases [RCV000511857] Chr18:136227..46171053 [GRCh37]
Chr18:18p11.32-q21.1		 pathogenic
GRCh37/hg19 18q12.1-12.2(chr18:30368042-36078516)x1 copy number loss See cases [RCV000511858] Chr18:30368042..36078516 [GRCh37]
Chr18:18q12.1-12.2		 likely pathogenic
GRCh37/hg19 18q11.1-22.1(chr18:18521285-64495798)x3 copy number gain See cases [RCV000511734] Chr18:18521285..64495798 [GRCh37]
Chr18:18q11.1-22.1		 pathogenic
GRCh37/hg19 18p11.21-q23(chr18:14869204-78014123)x3 copy number gain See cases [RCV000512030] Chr18:14869204..78014123 [GRCh37]
Chr18:18p11.21-q23		 pathogenic
GRCh37/hg19 18q11.2-21.1(chr18:24835114-46917217)x3 copy number gain See cases [RCV000511124] Chr18:24835114..46917217 [GRCh37]
Chr18:18q11.2-21.1		 likely benign
GRCh37/hg19 18p11.32-q23(chr18:136227-78014123) copy number gain See cases [RCV000511189] Chr18:136227..78014123 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
NM_012319.4(SLC39A6):c.614T>C (p.Ile205Thr) single nucleotide variant not specified [RCV004297392] Chr18:36126394 [GRCh38]
Chr18:33706357 [GRCh37]
Chr18:18q12.2		 uncertain significance
GRCh37/hg19 18q12.1-23(chr18:31879854-78014123)x3 copy number gain See cases [RCV000512425] Chr18:31879854..78014123 [GRCh37]
Chr18:18q12.1-23		 pathogenic
GRCh37/hg19 18q12.1-12.2(chr18:29711972-35866193)x1 copy number loss not provided [RCV000684043] Chr18:29711972..35866193 [GRCh37]
Chr18:18q12.1-12.2		 pathogenic
GRCh37/hg19 18q12.2(chr18:32988821-33701451)x3 copy number gain not provided [RCV000684010] Chr18:32988821..33701451 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1559C>T (p.Ala520Val) single nucleotide variant not specified [RCV004683745] Chr18:36114381 [GRCh38]
Chr18:33694344 [GRCh37]
Chr18:18q12.2		 uncertain significance
GRCh37/hg19 18q11.1-21.2(chr18:18539806-49926444)x2 copy number gain not provided [RCV000739776] Chr18:18539806..49926444 [GRCh37]
Chr18:18q11.1-21.2		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:12842-78015180)x3 copy number gain not provided [RCV000752245] Chr18:12842..78015180 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:13034-78015180)x3 copy number gain not provided [RCV000752246] Chr18:13034..78015180 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18q12.2(chr18:33554981-36939357) copy number loss not provided [RCV000767741] Chr18:33554981..36939357 [GRCh37]
Chr18:18q12.2		 pathogenic
GRCh37/hg19 18q11.2-21.2(chr18:20689919-49455212)x3 copy number gain not provided [RCV001006980] Chr18:20689919..49455212 [GRCh37]
Chr18:18q11.2-21.2		 pathogenic
NM_012319.4(SLC39A6):c.2248G>A (p.Val750Met) single nucleotide variant not specified [RCV004298361] Chr18:36109613 [GRCh38]
Chr18:33689576 [GRCh37]
Chr18:18q12.2		 uncertain significance
GRCh37/hg19 18q11.2-12.2(chr18:22868759-34335753)x1 copy number loss not provided [RCV001006964] Chr18:22868759..34335753 [GRCh37]
Chr18:18q11.2-12.2		 pathogenic
GRCh37/hg19 18q12.2(chr18:33384923-34561159)x3 copy number gain not provided [RCV001006965] Chr18:33384923..34561159 [GRCh37]
Chr18:18q12.2		 uncertain significance
GRCh37/hg19 18q11.2-23(chr18:23626739-78014976)x3 copy number gain not provided [RCV001537911] Chr18:23626739..78014976 [GRCh37]
Chr18:18q11.2-23		 pathogenic
GRCh37/hg19 18q11.2-12.2(chr18:23971647-33737300)x1 copy number loss See cases [RCV001263022] Chr18:23971647..33737300 [GRCh37]
Chr18:18q11.2-12.2		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:1-78077248) copy number gain Trisomy 18 [RCV002280660] Chr18:1..78077248 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
Single allele deletion Intellectual disability [RCV001787257] Chr18:1262336..53254747 [GRCh37]
Chr18:18p11.32-q21.2		 pathogenic
GRCh37/hg19 18p11.32-q23(chr18:136226-78014123) copy number gain not specified [RCV002052616] Chr18:136226..78014123 [GRCh37]
Chr18:18p11.32-q23		 pathogenic
GRCh37/hg19 18q12.2(chr18:33571456-34552945)x1 copy number loss not provided [RCV001836546] Chr18:33571456..34552945 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1846G>T (p.Ala616Ser) single nucleotide variant not specified [RCV004683746] Chr18:36112579 [GRCh38]
Chr18:33692542 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.437G>A (p.Cys146Tyr) single nucleotide variant not specified [RCV004233772] Chr18:36126571 [GRCh38]
Chr18:33706534 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1189G>A (p.Glu397Lys) single nucleotide variant not specified [RCV004158552] Chr18:36122222 [GRCh38]
Chr18:33702185 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1259C>T (p.Ser420Phe) single nucleotide variant not specified [RCV004091814] Chr18:36122152 [GRCh38]
Chr18:33702115 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1244G>A (p.Ser415Asn) single nucleotide variant not specified [RCV004213952] Chr18:36122167 [GRCh38]
Chr18:33702130 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.541A>G (p.Ser181Gly) single nucleotide variant not specified [RCV004227718] Chr18:36126467 [GRCh38]
Chr18:33706430 [GRCh37]
Chr18:18q12.2		 likely benign
NM_012319.4(SLC39A6):c.446A>G (p.His149Arg) single nucleotide variant not specified [RCV004117220] Chr18:36126562 [GRCh38]
Chr18:33706525 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.398A>G (p.Asn133Ser) single nucleotide variant not specified [RCV004177643] Chr18:36126610 [GRCh38]
Chr18:33706573 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.731T>C (p.Val244Ala) single nucleotide variant not specified [RCV004223331] Chr18:36126277 [GRCh38]
Chr18:33706240 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1376A>G (p.Glu459Gly) single nucleotide variant not specified [RCV004076325] Chr18:36116763 [GRCh38]
Chr18:33696726 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.652G>A (p.Val218Ile) single nucleotide variant not specified [RCV004147299] Chr18:36126356 [GRCh38]
Chr18:33706319 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.329G>A (p.Arg110His) single nucleotide variant not specified [RCV004197845] Chr18:36126679 [GRCh38]
Chr18:33706642 [GRCh37]
Chr18:18q12.2		 likely benign
NM_012319.4(SLC39A6):c.635A>G (p.Lys212Arg) single nucleotide variant not specified [RCV004135220] Chr18:36126373 [GRCh38]
Chr18:33706336 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1771G>A (p.Gly591Ser) single nucleotide variant not specified [RCV004075232] Chr18:36114169 [GRCh38]
Chr18:33694132 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.649G>T (p.Asp217Tyr) single nucleotide variant not specified [RCV004103577] Chr18:36126359 [GRCh38]
Chr18:33706322 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1052G>T (p.Arg351Leu) single nucleotide variant not specified [RCV004083881] Chr18:36123583 [GRCh38]
Chr18:33703546 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1568A>G (p.His523Arg) single nucleotide variant not specified [RCV004254636] Chr18:36114372 [GRCh38]
Chr18:33694335 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1429C>G (p.Leu477Val) single nucleotide variant not specified [RCV004270004] Chr18:36116710 [GRCh38]
Chr18:33696673 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1925G>T (p.Gly642Val) single nucleotide variant not specified [RCV004258298] Chr18:36111249 [GRCh38]
Chr18:33691212 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.227G>T (p.Arg76Ile) single nucleotide variant not specified [RCV004353224] Chr18:36126781 [GRCh38]
Chr18:33706744 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1183G>A (p.Ala395Thr) single nucleotide variant not specified [RCV004355616] Chr18:36122228 [GRCh38]
Chr18:33702191 [GRCh37]
Chr18:18q12.2		 uncertain significance
GRCh37/hg19 18q12.1-12.3(chr18:26595964-38643072)x1 copy number loss not provided [RCV003483335] Chr18:26595964..38643072 [GRCh37]
Chr18:18q12.1-12.3		 pathogenic
Single allele deletion Deletion of long arm of chromosome 18 [RCV004801487] Chr18:23614482..49306881 [GRCh38]
Chr18:18q11.2-21.1		 pathogenic
NM_012319.4(SLC39A6):c.1096G>T (p.Val366Phe) single nucleotide variant not specified [RCV004461583] Chr18:36123539 [GRCh38]
Chr18:33703502 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1463A>G (p.Asp488Gly) single nucleotide variant not specified [RCV004461589] Chr18:36116676 [GRCh38]
Chr18:33696639 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1757A>T (p.Glu586Val) single nucleotide variant not specified [RCV004461591] Chr18:36114183 [GRCh38]
Chr18:33694146 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1834C>A (p.Leu612Ile) single nucleotide variant not specified [RCV004461592] Chr18:36114106 [GRCh38]
Chr18:33694069 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1982A>T (p.Asn661Ile) single nucleotide variant not specified [RCV004461594] Chr18:36111192 [GRCh38]
Chr18:33691155 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.743G>A (p.Arg248Gln) single nucleotide variant not specified [RCV004461598] Chr18:36126265 [GRCh38]
Chr18:33706228 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.797A>G (p.Asn266Ser) single nucleotide variant not specified [RCV004461599] Chr18:36124693 [GRCh38]
Chr18:33704656 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1055T>A (p.Val352Glu) single nucleotide variant not specified [RCV004461582] Chr18:36123580 [GRCh38]
Chr18:33703543 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1133T>C (p.Leu378Pro) single nucleotide variant not specified [RCV004461584] Chr18:36123502 [GRCh38]
Chr18:33703465 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.113C>T (p.Pro38Leu) single nucleotide variant not specified [RCV004461585] Chr18:36126895 [GRCh38]
Chr18:33706858 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1167T>A (p.His389Gln) single nucleotide variant not specified [RCV004461586] Chr18:36122244 [GRCh38]
Chr18:33702207 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1241A>G (p.Glu414Gly) single nucleotide variant not specified [RCV004461587] Chr18:36122170 [GRCh38]
Chr18:33702133 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1598C>T (p.Pro533Leu) single nucleotide variant not specified [RCV004461590] Chr18:36114342 [GRCh38]
Chr18:33694305 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.328C>T (p.Arg110Cys) single nucleotide variant not specified [RCV004461596] Chr18:36126680 [GRCh38]
Chr18:33706643 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.583G>A (p.Val195Ile) single nucleotide variant not specified [RCV004461597] Chr18:36126425 [GRCh38]
Chr18:33706388 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1960G>T (p.Val654Phe) single nucleotide variant not specified [RCV004461593] Chr18:36111214 [GRCh38]
Chr18:33691177 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.2088A>T (p.Leu696Phe) single nucleotide variant not specified [RCV004461595] Chr18:36111086 [GRCh38]
Chr18:33691049 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1996A>G (p.Met666Val) single nucleotide variant not specified [RCV004674701] Chr18:36111178 [GRCh38]
Chr18:33691141 [GRCh37]
Chr18:18q12.2		 uncertain significance
NM_012319.4(SLC39A6):c.1180C>T (p.Pro394Ser) single nucleotide variant not specified [RCV004674702] Chr18:36122231 [GRCh38]
Chr18:33702194 [GRCh37]
Chr18:18q12.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:710
Count of miRNA genes:401
Interacting mature miRNAs:434
Transcripts:ENST00000269187, ENST00000440549, ENST00000586829, ENST00000590986
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407045746GWAS694722_Hsurvival time, squamous cell carcinoma, esophageal carcinoma QTL GWAS694722 (human)4e-08survival time, squamous cell carcinoma, esophageal carcinoma183611415736114158Human

Markers in Region
WI-14709  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371833,688,533 - 33,688,658UniSTSGRCh37
Build 361831,942,531 - 31,942,656RGDNCBI36
Celera1830,496,419 - 30,496,544RGD
Cytogenetic Map18q12.2UniSTS
HuRef1830,547,438 - 30,547,563UniSTS
GeneMap99-GB4 RH Map18293.04UniSTS
Whitehead-RH Map18287.8UniSTS
NCBI RH Map18405.2UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001099406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC091060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK097938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX336036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA443894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CQ834422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC369482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC410860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC414741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DR762943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U41060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000269187   ⟹   ENSP00000269187
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1836,108,531 - 36,129,340 (-)Ensembl
Ensembl Acc Id: ENST00000440549   ⟹   ENSP00000401139
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1836,111,000 - 36,129,385 (-)Ensembl
Ensembl Acc Id: ENST00000586829   ⟹   ENSP00000467724
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1836,111,056 - 36,122,115 (-)Ensembl
Ensembl Acc Id: ENST00000590986   ⟹   ENSP00000465915
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1836,109,148 - 36,129,381 (-)Ensembl
RefSeq Acc Id: NM_001099406   ⟹   NP_001092876
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381836,110,994 - 36,129,340 (-)NCBI
GRCh371833,688,494 - 33,709,357 (-)ENTREZGENE
Build 361831,944,961 - 31,963,355 (-)NCBI Archive
HuRef1830,547,399 - 30,568,273 (-)ENTREZGENE
CHM1_11833,618,043 - 33,636,438 (-)NCBI
T2T-CHM13v2.01836,302,560 - 36,320,904 (-)NCBI
Sequence:
RefSeq Acc Id: NM_012319   ⟹   NP_036451
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381836,108,531 - 36,129,340 (-)NCBI
GRCh371833,688,494 - 33,709,357 (-)ENTREZGENE
Build 361831,942,492 - 31,963,355 (-)NCBI Archive
HuRef1830,547,399 - 30,568,273 (-)ENTREZGENE
CHM1_11833,615,574 - 33,636,438 (-)NCBI
T2T-CHM13v2.01836,300,097 - 36,320,904 (-)NCBI
Sequence:
RefSeq Acc Id: NP_036451   ⟸   NM_012319
- Peptide Label: isoform 1 precursor
- UniProtKB: Q8IXR3 (UniProtKB/Swiss-Prot),   Q13433 (UniProtKB/Swiss-Prot),   B4E224 (UniProtKB/Swiss-Prot),   B4DR49 (UniProtKB/Swiss-Prot),   Q96HP5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001092876   ⟸   NM_001099406
- Peptide Label: isoform 2
- UniProtKB: B4DWH6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000269187   ⟸   ENST00000269187
Ensembl Acc Id: ENSP00000401139   ⟸   ENST00000440549
Ensembl Acc Id: ENSP00000467724   ⟸   ENST00000586829
Ensembl Acc Id: ENSP00000465915   ⟸   ENST00000590986

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q13433-F1-model_v2 AlphaFold Q13433 1-755 view protein structure

Promoters
RGD ID:6795003
Promoter ID:HG_KWN:27892
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001099406,   NM_012319
Position:
Human AssemblyChrPosition (strand)Source
Build 361831,963,246 - 31,964,037 (-)MPROMDB
RGD ID:7237201
Promoter ID:EPDNEW_H24346
Type:initiation region
Name:SLC39A6_1
Description:solute carrier family 39 member 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381836,129,337 - 36,129,397EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:18607 AgrOrtholog
COSMIC SLC39A6 COSMIC
Ensembl Genes ENSG00000141424 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000269187 ENTREZGENE
  ENST00000269187.10 UniProtKB/Swiss-Prot
  ENST00000440549 ENTREZGENE
  ENST00000440549.6 UniProtKB/Swiss-Prot
  ENST00000586829.1 UniProtKB/TrEMBL
  ENST00000590986.5 UniProtKB/Swiss-Prot
GTEx ENSG00000141424 GTEx
HGNC ID HGNC:18607 ENTREZGENE
Human Proteome Map SLC39A6 Human Proteome Map
InterPro ZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZIP_Transporter UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:25800 UniProtKB/Swiss-Prot
NCBI Gene 25800 ENTREZGENE
OMIM 608731 OMIM
PANTHER SOLUTE CARRIER FAMILY 39 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC TRANSPORTER ZIP6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Zip UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134905551 PharmGKB
UniProt B4DR49 ENTREZGENE
  B4DWH6 ENTREZGENE, UniProtKB/TrEMBL
  B4E224 ENTREZGENE
  K7EQ91_HUMAN UniProtKB/TrEMBL
  Q13433 ENTREZGENE
  Q8IXR3 ENTREZGENE
  Q96HP5 ENTREZGENE
  S39A6_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B4DR49 UniProtKB/Swiss-Prot
  B4E224 UniProtKB/Swiss-Prot
  Q8IXR3 UniProtKB/Swiss-Prot
  Q96HP5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-23 SLC39A6  solute carrier family 39 member 6  SLC39A6  solute carrier family 39 (zinc transporter), member 6  Symbol and/or name change 5135510 APPROVED