Slc39a11 (solute carrier family 39, member 11) - Rat Genome Database

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Gene: Slc39a11 (solute carrier family 39, member 11) Rattus norvegicus
Analyze
Symbol: Slc39a11
Name: solute carrier family 39, member 11
RGD ID: 1311981
Description: Predicted to enable copper ion transmembrane transporter activity and zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion import across plasma membrane. Predicted to be located in Golgi apparatus; nucleus; and plasma membrane. Predicted to be active in membrane. Orthologous to human SLC39A11 (solute carrier family 39 member 11); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC287796; solute carrier family 39 (metal ion transporter), member 11; solute carrier family 39 member 11; zinc transporter ZIP11; ZIP-11; zrt- and Irt-like protein 11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81098,775,155 - 99,196,302 (-)NCBIGRCr8
mRatBN7.21098,275,958 - 98,697,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1098,275,960 - 98,611,295 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10103,339,869 - 103,663,521 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010102,802,903 - 103,126,556 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01098,197,396 - 98,531,352 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010101,754,842 - 102,169,100 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10101,754,830 - 102,084,035 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010101,428,720 - 101,848,639 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410102,863,399 - 103,189,081 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110102,877,768 - 103,203,451 (-)NCBI
Celera1096,892,699 - 97,219,427 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
7,12-dimethyltetraphene  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cyproconazole  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dopamine  (EXP)
dorsomorphin  (ISO)
epoxiconazole  (ISO)
fenoldopam  (EXP)
formaldehyde  (ISO)
glycidol  (EXP)
glyphosate  (EXP)
indole-3-methanol  (EXP)
indometacin  (ISO)
inulin  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
N-acetyl-1,4-benzoquinone imine  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO,ISS)
Golgi apparatus  (IEA,ISO,ISS)
membrane  (IBA,IEA)
nucleus  (IEA,ISO,ISS)
plasma membrane  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:21702047   PMID:23643525   PMID:24089422  


Genomics

Comparative Map Data
Slc39a11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81098,775,155 - 99,196,302 (-)NCBIGRCr8
mRatBN7.21098,275,958 - 98,697,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1098,275,960 - 98,611,295 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10103,339,869 - 103,663,521 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010102,802,903 - 103,126,556 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01098,197,396 - 98,531,352 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010101,754,842 - 102,169,100 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10101,754,830 - 102,084,035 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010101,428,720 - 101,848,639 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410102,863,399 - 103,189,081 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110102,877,768 - 103,203,451 (-)NCBI
Celera1096,892,699 - 97,219,427 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
SLC39A11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381772,645,949 - 73,092,688 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1772,645,949 - 73,092,712 (-)EnsemblGRCh38hg38GRCh38
GRCh371770,642,088 - 71,088,827 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361768,153,683 - 68,600,427 (-)NCBINCBI36Build 36hg18NCBI36
Build 341768,153,683 - 68,600,427NCBI
Celera1767,213,461 - 67,671,934 (-)NCBICelera
Cytogenetic Map17q24.3-q25.1NCBI
HuRef1766,033,664 - 66,497,349 (-)NCBIHuRef
CHM1_11770,705,944 - 71,153,067 (-)NCBICHM1_1
T2T-CHM13v2.01773,518,976 - 73,981,577 (-)NCBIT2T-CHM13v2.0
Slc39a11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911113,135,677 - 113,541,050 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11113,135,679 - 113,540,905 (-)EnsemblGRCm39 Ensembl
GRCm3811113,244,851 - 113,650,200 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11113,244,853 - 113,650,079 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711113,106,169 - 113,427,129 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611113,060,944 - 113,381,858 (-)NCBIMGSCv36mm8
Celera11125,002,068 - 125,320,378 (-)NCBICelera
Celera11134,571,484 - 134,573,124 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1178.74NCBI
Slc39a11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955478123,887 - 489,791 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955478123,873 - 489,704 (+)NCBIChiLan1.0ChiLan1.0
SLC39A11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21988,643,336 - 89,109,232 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11793,468,319 - 93,934,134 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01766,554,202 - 67,019,899 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11772,012,486 - 72,476,865 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1772,014,122 - 72,472,918 (-)Ensemblpanpan1.1panPan2
SLC39A11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.196,978,031 - 7,244,985 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha97,601,802 - 8,003,712 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.097,653,100 - 8,055,260 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl97,724,580 - 8,055,230 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.197,693,507 - 8,096,086 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.097,796,370 - 8,197,028 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.097,857,406 - 8,260,622 (+)NCBIUU_Cfam_GSD_1.0
Slc39a11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056027,534,401 - 7,709,948 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366551,103,728 - 1,442,716 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366551,103,805 - 1,208,723 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC39A11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl127,759,820 - 8,204,246 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1127,759,732 - 8,204,249 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2128,040,168 - 8,500,314 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC39A11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11648,440,063 - 48,999,755 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1648,440,108 - 49,000,037 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607719,261,446 - 19,827,471 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc39a11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248012,734,544 - 3,196,570 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248012,734,761 - 3,226,349 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc39a11
2859 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:90
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000042156
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093223816107057807Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090404397107211142Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)107877551698279596Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1092238497101012337Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
1578672Bmd16Bone mineral density QTL 166.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)1096703043107057807Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087307617107211142Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090627439107211142Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1090627439107057807Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
1578663Bss18Bone structure and strength QTL 183.6femur width (VT:1000666)femoral neck width (CMO:0001695)1096703043107057807Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1080515287101325465Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1090404397107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1088539139107211142Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
1576313Pia25Pristane induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096120911104060283Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1576307Cia28Collagen induced arthritis QTL 28joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1096120911104060283Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1094759759107211142Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1085565469103884409Rat
631539Oia6Oil induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1097010147104670812Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087055121107211142Rat
61436Cia5Collagen induced arthritis QTL 54.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1091228102104060283Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat

Markers in Region
D10Rat201  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21098,279,434 - 98,279,596 (+)MAPPERmRatBN7.2
Rnor_6.010101,758,317 - 101,758,478NCBIRnor6.0
Rnor_5.010101,432,195 - 101,432,356UniSTSRnor5.0
RGSC_v3.410102,865,474 - 102,865,929RGDRGSC3.4
RGSC_v3.410102,865,504 - 102,865,665UniSTSRGSC3.4
RGSC_v3.110102,879,844 - 102,880,299RGD
Celera1096,894,804 - 96,894,965UniSTS
RH 3.4 Map101119.0UniSTS
RH 3.4 Map101119.0RGD
SHRSP x BN Map1083.68UniSTS
SHRSP x BN Map1083.68RGD
Cytogenetic Map10q32.1UniSTS
D10Rat230  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21098,334,951 - 98,335,153 (+)MAPPERmRatBN7.2
Rnor_6.010101,814,047 - 101,814,248NCBIRnor6.0
Rnor_5.010101,487,925 - 101,488,126UniSTSRnor5.0
RGSC_v3.410102,920,914 - 102,921,116RGDRGSC3.4
RGSC_v3.410102,920,915 - 102,921,116UniSTSRGSC3.4
RGSC_v3.110102,935,284 - 102,935,486RGD
Celera1096,949,941 - 96,950,142UniSTS
SHRSP x BN Map1084.82UniSTS
SHRSP x BN Map1084.82RGD
Cytogenetic Map10q32.1UniSTS
D10Rat231  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21098,554,101 - 98,554,338 (+)MAPPERmRatBN7.2
Rnor_6.010102,032,317 - 102,032,553NCBIRnor6.0
Rnor_5.010101,705,454 - 101,705,690UniSTSRnor5.0
RGSC_v3.410103,140,164 - 103,140,401RGDRGSC3.4
RGSC_v3.410103,140,165 - 103,140,401UniSTSRGSC3.4
RGSC_v3.110103,154,534 - 103,154,771RGD
Celera1097,168,598 - 97,168,834UniSTS
SHRSP x BN Map1083.4UniSTS
SHRSP x BN Map1083.4RGD
Cytogenetic Map10q32.1UniSTS
AU048139  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21098,466,486 - 98,466,631 (+)MAPPERmRatBN7.2
Rnor_6.010101,944,808 - 101,944,952NCBIRnor6.0
Rnor_5.010101,618,518 - 101,618,662UniSTSRnor5.0
RGSC_v3.410103,052,433 - 103,052,577UniSTSRGSC3.4
Celera1097,081,114 - 97,081,258UniSTS
Cytogenetic Map10q32.1UniSTS
D7Arb609a  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21098,302,467 - 98,303,434 (+)MAPPERmRatBN7.2
Rnor_6.010101,780,904 - 101,781,870NCBIRnor6.0
Rnor_5.010101,454,782 - 101,455,748UniSTSRnor5.0
RGSC_v3.410102,888,434 - 102,889,400UniSTSRGSC3.4
Celera1096,917,468 - 96,918,434UniSTS
Cytogenetic Map10q32.1UniSTS
RH141506  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21098,456,253 - 98,456,433 (+)MAPPERmRatBN7.2
Rnor_6.010101,934,575 - 101,934,754NCBIRnor6.0
Rnor_5.010101,608,285 - 101,608,464UniSTSRnor5.0
RGSC_v3.410103,042,202 - 103,042,381UniSTSRGSC3.4
Celera1097,070,876 - 97,071,055UniSTS
Cytogenetic Map10q32.1UniSTS
fc37g07.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21098,279,538 - 98,280,010 (+)MAPPERmRatBN7.2
Rnor_6.010101,758,421 - 101,758,892NCBIRnor6.0
Rnor_5.010101,432,299 - 101,432,770UniSTSRnor5.0
RGSC_v3.41722,612,449 - 22,613,616UniSTSRGSC3.4
RGSC_v3.410102,865,608 - 102,866,079UniSTSRGSC3.4
Celera1716,199,374 - 16,200,543UniSTS
Celera1096,894,908 - 96,895,379UniSTS
Cytogenetic Map10q32.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 8 35 2 21 1
Low 43 49 41 19 41 8 11 39 33 20 10 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001013042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006247670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000042156   ⟹   ENSRNOP00000039028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1098,275,960 - 98,608,165 (-)Ensembl
Rnor_6.0 Ensembl10101,754,830 - 102,084,035 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097833   ⟹   ENSRNOP00000091972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1098,277,328 - 98,611,295 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108406   ⟹   ENSRNOP00000083419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1098,277,328 - 98,608,570 (-)Ensembl
RefSeq Acc Id: NM_001013042   ⟹   NP_001013060
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,776,525 - 99,110,456 (-)NCBI
mRatBN7.21098,277,328 - 98,611,295 (-)NCBI
Rnor_6.010101,756,212 - 102,083,480 (-)NCBI
Rnor_5.010101,428,720 - 101,848,639 (-)NCBI
RGSC_v3.410102,863,399 - 103,189,081 (-)RGD
Celera1096,892,699 - 97,219,427 (-)RGD
Sequence:
RefSeq Acc Id: XM_006247664   ⟹   XP_006247726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,107,430 (-)NCBI
mRatBN7.21098,275,958 - 98,608,260 (-)NCBI
Rnor_6.010101,754,842 - 102,080,572 (-)NCBI
Rnor_5.010101,428,720 - 101,848,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247668   ⟹   XP_006247730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,110,499 (-)NCBI
mRatBN7.21098,275,958 - 98,611,538 (-)NCBI
Rnor_6.010101,754,842 - 102,083,542 (-)NCBI
Rnor_5.010101,428,720 - 101,848,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247670   ⟹   XP_006247732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,196,302 (-)NCBI
mRatBN7.21098,275,958 - 98,697,021 (-)NCBI
Rnor_6.010101,754,842 - 102,169,100 (-)NCBI
Rnor_5.010101,428,720 - 101,848,639 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597148   ⟹   XP_017452637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,110,829 (-)NCBI
mRatBN7.21098,275,958 - 98,611,786 (-)NCBI
Rnor_6.010101,754,842 - 102,083,817 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039085655   ⟹   XP_038941583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,107,761 (-)NCBI
mRatBN7.21098,275,958 - 98,608,588 (-)NCBI
RefSeq Acc Id: XM_039085656   ⟹   XP_038941584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,108,698 (-)NCBI
mRatBN7.21098,275,958 - 98,609,533 (-)NCBI
RefSeq Acc Id: XM_039085657   ⟹   XP_038941585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,196,302 (-)NCBI
mRatBN7.21098,275,958 - 98,697,042 (-)NCBI
RefSeq Acc Id: XM_039085658   ⟹   XP_038941586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,893,328 - 99,106,741 (-)NCBI
mRatBN7.21098,394,127 - 98,607,578 (-)NCBI
RefSeq Acc Id: XM_039085659   ⟹   XP_038941587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,893,328 - 99,107,434 (-)NCBI
mRatBN7.21098,394,127 - 98,607,578 (-)NCBI
RefSeq Acc Id: XM_039085660   ⟹   XP_038941588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 98,957,419 (-)NCBI
mRatBN7.21098,275,958 - 98,458,242 (-)NCBI
RefSeq Acc Id: XM_063268765   ⟹   XP_063124835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,107,747 (-)NCBI
RefSeq Acc Id: XM_063268766   ⟹   XP_063124836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,196,302 (-)NCBI
RefSeq Acc Id: XM_063268767   ⟹   XP_063124837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81098,775,155 - 99,196,302 (-)NCBI
RefSeq Acc Id: NP_001013060   ⟸   NM_001013042
- UniProtKB: Q6P6S2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006247732   ⟸   XM_006247670
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006247730   ⟸   XM_006247668
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006247726   ⟸   XM_006247664
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QK09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452637   ⟸   XM_017597148
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000039028   ⟸   ENSRNOT00000042156
RefSeq Acc Id: XP_038941585   ⟸   XM_039085657
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038941584   ⟸   XM_039085656
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038941583   ⟸   XM_039085655
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038941588   ⟸   XM_039085660
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038941587   ⟸   XM_039085659
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038941586   ⟸   XM_039085658
- Peptide Label: isoform X8
RefSeq Acc Id: ENSRNOP00000091972   ⟸   ENSRNOT00000097833
RefSeq Acc Id: ENSRNOP00000083419   ⟸   ENSRNOT00000108406
RefSeq Acc Id: XP_063124837   ⟸   XM_063268767
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063124836   ⟸   XM_063268766
- Peptide Label: isoform X5
- UniProtKB: Q6P6S2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063124835   ⟸   XM_063268765
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZZC3 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P6S2-F1-model_v2 AlphaFold Q6P6S2 1-335 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311981 AgrOrtholog
BioCyc Gene G2FUF-22766 BioCyc
Ensembl Genes ENSRNOG00000031213 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042156.6 UniProtKB/TrEMBL
  ENSRNOT00000097833.1 UniProtKB/Swiss-Prot
  ENSRNOT00000108406.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5598901 IMAGE-MGC_LOAD
InterPro ZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:287796 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72592 IMAGE-MGC_LOAD
NCBI Gene 287796 ENTREZGENE
PANTHER ZINC TRANSPORTER ZIP11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC/IRON TRANSPORTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Zip UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc39a11 PhenoGen
RatGTEx ENSRNOG00000031213 RatGTEx
UniProt A0A8I5ZZC3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QK09 ENTREZGENE, UniProtKB/TrEMBL
  A6HKF6_RAT UniProtKB/TrEMBL
  A6HKF8_RAT UniProtKB/TrEMBL
  Q6P6S2 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-02 Slc39a11  solute carrier family 39, member 11  Slc39a11  solute carrier family 39 (metal ion transporter), member 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Slc39a11  solute carrier family 39 (metal ion transporter), member 11  Slc39a11_predicted  solute carrier family 39 (metal ion transporter), member 11 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Slc39a11_predicted  solute carrier family 39 (metal ion transporter), member 11 (predicted)      Symbol and Name status set to approved 70820 APPROVED