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Gene: Chsy1 (chondroitin sulfate synthase 1) Rattus norvegicus

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Symbol:

Chsy1

Name:

chondroitin sulfate synthase 1

RGD ID:

1311904

Description:

Predicted to enable N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity and glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Involved in response to nutrient levels. Predicted to be located in extracellular region. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in temtamy preaxial brachydactyly syndrome. Orthologous to human CHSY1 (chondroitin sulfate synthase 1); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

carbohydrate (chondroitin) synthase 1; LOC292999

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CHSY1 (chondroitin sulfate synthase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Chsy1 (chondroitin sulfate synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Chsy1 (chondroitin sulfate synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CHSY1 (chondroitin sulfate synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CHSY1 (chondroitin sulfate synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Chsy1 (chondroitin sulfate synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CHSY1 (chondroitin sulfate synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CHSY1 (chondroitin sulfate synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Chsy1 (chondroitin sulfate synthase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CHSY1 (chondroitin sulfate synthase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CHSY1 (chondroitin sulfate synthase 1)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Chsy1 (chondroitin sulfate synthase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Chsy1 (chondroitin sulfate synthase 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	chsy1 (chondroitin sulfate synthase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	chsy1 (chondroitin sulfate synthase 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9220	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9220	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	sqv-5	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	sqv-5	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	chsy1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Chsy1^{Tn(sb-T2/Bart3)2.165Mcwi}

Genetic Models:

F344-Chsy1^{Tn(sb-T2/Bart3)2.165Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	129,100,088 - 129,161,167 (+)	NCBI		GRCr8
GRCr8 Ensembl	1	129,100,041 - 129,161,081 (+)	Ensembl		GRCr8 Ensembl
mRatBN7.2	1	119,689,626 - 119,750,711 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	119,686,350 - 119,750,601 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	127,682,577 - 127,743,312 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	134,854,019 - 134,914,754 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	127,663,508 - 127,724,487 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	127,010,587 - 127,071,570 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	127,010,588 - 127,071,570 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	128,095,353 - 128,156,041 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	120,539,002 - 120,600,102 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	111,901,152 - 111,961,962 (+)	NCBI		Celera
RGSC_v3.1	1	120,616,912 - 120,677,080 (+)	NCBI
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 15q26-qter deletion syndrome (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

Hearing Loss (ISO)

temtamy preaxial brachydactyly syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (EXP)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (EXP,ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

3',5'-cyclic AMP (EXP)

3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine (ISO)

4,4'-diaminodiphenylmethane (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

chloropicrin (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dioxygen (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

genistein (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

L-methionine (ISO)

lipopolysaccharide (ISO)

methimazole (EXP)

N-nitrosodimethylamine (EXP)

nickel dichloride (EXP)

nickel subsulfide (EXP)

okadaic acid (ISO)

panobinostat (ISO)

paracetamol (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

poly(I:C) (EXP)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (EXP)

Soman (EXP)

sunitinib (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

Thrombin (ISO)

titanium dioxide (ISO)

triadimefon (EXP)

trichostatin A (ISO)

triphenyl phosphate (EXP,ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bone morphogenesis (IEA,ISO)

cartilage development (IEA,ISO)

chondrocyte development (IEA,ISO)

chondroitin sulfate proteoglycan biosynthetic process (IBA,IEA,ISO)

negative regulation of ossification (IEA,ISO)

positive regulation of smoothened signaling pathway (IEA,ISO)

proximal/distal pattern formation (IEA,ISO)

response to nutrient levels (IEP)

sulfation (IEA,ISO)

Cellular Component

extracellular region (IEA,ISO)

Golgi apparatus (IEA,ISO)

Golgi cisterna membrane (IEA)

membrane (IEA)

Molecular Function

acetylgalactosaminyltransferase activity (IEA)

glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity (IBA,IEA,ISO)

glycosyltransferase activity (IEA,ISO)

metal ion binding (IEA)

N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity (IEA,ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

chondroitin sulfate biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation
7.	Glycosaminoglycan polymerization may enable osmotically inactive Na+ storage in the skin.	Titze J, etal., Am J Physiol Heart Circ Physiol. 2004 Jul;287(1):H203-8. Epub 2004 Feb 19.

Additional References at PubMed

PMID:11514575	PMID:19946888	PMID:21129727	PMID:22280990	PMID:22952769	PMID:26356269

Genomics

Comparative Map Data

Chsy1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	129,100,088 - 129,161,167 (+)	NCBI		GRCr8
GRCr8 Ensembl	1	129,100,041 - 129,161,081 (+)	Ensembl		GRCr8 Ensembl
mRatBN7.2	1	119,689,626 - 119,750,711 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	119,686,350 - 119,750,601 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	127,682,577 - 127,743,312 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	134,854,019 - 134,914,754 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	127,663,508 - 127,724,487 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	127,010,587 - 127,071,570 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	127,010,588 - 127,071,570 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	128,095,353 - 128,156,041 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	120,539,002 - 120,600,102 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	111,901,152 - 111,961,962 (+)	NCBI		Celera
RGSC_v3.1	1	120,616,912 - 120,677,080 (+)	NCBI
Cytogenetic Map	1	q22	NCBI

CHSY1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	101,175,727 - 101,252,048 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	101,175,727 - 101,252,048 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	101,715,932 - 101,792,253 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	99,533,455 - 99,609,649 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	99,533,455 - 99,609,649	NCBI
Celera	15	78,129,035 - 78,204,977 (-)	NCBI		Celera
Cytogenetic Map	15	q26.3	NCBI
HuRef	15	77,838,413 - 77,914,374 (-)	NCBI		HuRef
CHM1_1	15	101,556,975 - 101,633,122 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	98,930,755 - 99,007,076 (-)	NCBI		T2T-CHM13v2.0

Chsy1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	65,759,240 - 65,823,546 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	65,759,263 - 65,823,546 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	66,109,492 - 66,173,798 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	66,109,515 - 66,173,798 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	73,254,401 - 73,318,684 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	65,988,465 - 66,052,748 (+)	NCBI		MGSCv36	mm8
Celera	7	63,545,296 - 63,619,383 (+)	NCBI		Celera
Cytogenetic Map	7	C	NCBI

Chsy1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	28,070,710 - 28,135,590 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	28,070,981 - 28,136,848 (-)	NCBI	ChiLan1.0	ChiLan1.0

CHSY1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	90,765,804 - 90,841,828 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	94,466,529 - 94,543,052 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	79,901,340 - 79,976,067 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	99,186,705 - 99,259,882 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	99,186,705 - 99,260,591 (-)	Ensembl	panpan1.1		panPan2

CHSY1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	39,844,227 - 39,916,484 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	39,844,195 - 40,021,573 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	42,532,031 - 42,605,585 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	40,234,309 - 40,307,861 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	40,235,605 - 40,306,490 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	39,767,324 - 39,840,760 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	40,004,150 - 40,077,669 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	40,207,051 - 40,279,606 (+)	NCBI		UU_Cfam_GSD_1.0

Chsy1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	143,648,412 - 143,720,663 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936483	2,613,820 - 2,686,276 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936483	2,613,820 - 2,685,986 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CHSY1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	139,730,721 - 139,804,657 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	139,730,703 - 139,804,458 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	155,960,054 - 156,033,821 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CHSY1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	19,633,335 - 19,707,547 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	19,632,026 - 19,707,425 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	26,833,395 - 26,907,460 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Chsy1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624768	3,567,770 - 3,628,360 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Chsy1
211 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	809
Count of miRNA genes:	303
Interacting mature miRNAs:	378
Transcripts:	ENSRNOT00000016939
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	176289080	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	101228864	146228864	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
631684	Bp117	Blood pressure QTL 117	8.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	120082258	165082258	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	112521556	157521556	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	128019551	173019551	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
61399	Tcat1	Tongue tumor resistance QTL 1	3.3		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)	1	108680016	153680016	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	91302413	136302413	Rat
631569	Bp93	Blood pressure QTL 93		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	131244255	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	102359314	153680016	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	127329268	206393015	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	112521556	157521556	Rat
2317833	Alcrsp19	Alcohol response QTL 19	12.4	0.001	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	124975316	152612788	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	111949780	160574007	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)	1	92683681	137683681	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
1641897	Alcrsp1	Alcohol response QTL 1			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	92683681	137683681	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	97582336	142582336	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	116099376	191260518	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	101594089	146594089	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	100345976	145345976	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	96717367	160111531	Rat
61370	Mcs3	Mammary carcinoma susceptibility QTL 3	2.15		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	111404407	142582336	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat

Markers in Region

D1Rat185

Rat Assembly	Chr	Position (strand)	Source
Celera	1	111,906,278 - 111,906,428	UniSTS
RH 3.4 Map	1	1448.59	RGD
RH 3.4 Map	1	1448.59	UniSTS
SHRSP x BN Map	1	56.5	UniSTS
SHRSP x BN Map	1	56.5	RGD
FHH x ACI Map	1	57.02	RGD
Cytogenetic Map	1	q22	UniSTS

AI598496

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	119,749,741 - 119,749,948 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	127,070,711 - 127,070,917	NCBI	Rnor6.0
Rnor_5.0	1	128,155,182 - 128,155,388	UniSTS	Rnor5.0
RGSC_v3.4	1	120,599,243 - 120,599,449	UniSTS	RGSC3.4
Celera	1	111,961,103 - 111,961,309	UniSTS
RH 3.4 Map	1	1447.0	UniSTS
Cytogenetic Map	1	q22	UniSTS

Genetic Models

This gene Chsy1 is modified in the following models/strains:

F344-Chsy1^{Tn(sb-T2/Bart3)2.165Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	11	49	113	91	90	59	25	59	6	218	97	11	93	45	60	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000016939 ⟹ ENSRNOP00000016939

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	129,100,041 - 129,161,081 (+)	Ensembl
mRatBN7.2 Ensembl	1	119,686,350 - 119,750,601 (+)	Ensembl
Rnor_6.0 Ensembl	1	127,010,588 - 127,071,570 (+)	Ensembl

RefSeq Acc Id:

NM_001106268 ⟹ NP_001099738

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	129,100,088 - 129,161,058 (+)	NCBI
mRatBN7.2	1	119,689,626 - 119,750,601 (+)	NCBI
Rnor_6.0	1	127,010,587 - 127,071,570 (+)	NCBI
Rnor_5.0	1	128,095,353 - 128,156,041 (+)	NCBI
RGSC_v3.4	1	120,539,002 - 120,600,102 (+)	RGD
Celera	1	111,901,152 - 111,961,962 (+)	RGD

Sequence:

show sequence

CGCGCGGCCGGCGCGCCTGGCTCAGCATGCTGCTCGGGCTCGTGCTGGGCTTCGTGCTGGCCTC
GCGACTCGTCCTGCCCCGCGCCTCGGAGCTGAAGCGAGTGGGCCCGCGGCGGCGCCCCAATCCC
GAGGGATGCCGGCCAGGACAGGCAGCGTCGCAGCCCGGCGGTGCTCCGGGGGATGCGCGCGGGG
CGCAGCTCTGGCCGCAGGGCTCGGCCGCGGAGGGCGTCCCGCGCGACAGGAACTTTCTCTTCGT
GGGAGTCATGACCGCCCAGAAATACCTGCAGACTCGCGCCGTGGCCGCTTACAGAACATGGTCC
AAGACAATTCCCGGGAAGGTTGAGTTCTTCTCTAGTGAGGGTTCAGACACATCTATACCCATTC
CAGTAGTGCCACTGAGGGGTGTGGACGACTCCTATCCCCCCCAGAAGAAGTCTTTCATGATGCT
CAAGTACATGCACGATCACTACTTGGACAAGTACGAATGGTTTATGAGAGCAGATGATGATGTC
TACATCAAGGGAGATCGTCTGGAGAGCTTTCTGAGGAGTTTGAATAGCAGCGAGCCCCTCTTTC
TCGGGCAGACAGGACTGGGCACCACTGAAGAAATGGGGAAACTGGCTCTTGAGCCTGGAGAGAA
CTTCTGCATGGGGGGACCTGGTGTGATTCTGAGCCGGGAAGTGCTTCGGAGAATGGCACCACAC
ATTGGCAAGTGTCTCCGGGAAATGTACACCACCCACGAGGATGTAGAGGTGGGGAGGTGCGTCC
GGAGATTCGCAGGCGTGCAGTGCGTCTGGTCATATGAGATGCAGCAGCTTTTTTACGAGAATTA
TGAACAGAACAAGAAAGGGTACATTAGAGATCTCCATAGCAGTAAAATCCACCGAGCGATCACT
TTACACCCCAACAAAAACCCGCCCTACCAGTACAGGCTACACAGTTACATGCTCAGCCGCAAGA
TCGCTGAGCTGCGCCATCGCACAATCCAGCTGCACCGGGAGATCGTCCTGATGAGCAAGTACAG
CAGCACGGAAATCCAGAAGGAAGACCTCCAGCTGGGCATCCCTCCCTCCTTCATGCGCTTTCAG
GCCCGCCAGCGAGAGGAGATCCTGGAGTGGGAGTTTCTGACTGGGAAATACTTATATTCAGCCA
CGGAAGGCCAGCCTCCCCGGAGAGGGATGGACTCAGCGCAGAGGGAGGCCTTGGATGACATTGT
CCTGCAAGTGATGGAGATGATCAATGCCAATGCCAAGACCCGGGGCCGCATCATCGACTTCAAG
GAGATCCAGTATGGCTACAGACGCGTGAATCCCATGTACGGGGCAGAGTACATCCTGGATCTGC
TGCTCCTGTATAAGAAGCACAAAGGGAAGAAGATGACGGTCCCTGTGAGGAGGCACGCGTACCT
GCAGCAGACCTTCAGCAAGATCCAGTTTGTGGAGCATGAGGGCCTGGATGCACAAGAGCTCGCT
GACAGAATCAACCAGGACTCTGGGTCCCTGTCATTCCTCTCCAATTCCTTGAAGAAGCTCGTTC
CCTTCCAGCTTCCTGGATCCAAGATGGAGCACAAAGAGCCCAAAGAAAAGAAGATAAACATTCT
GATCCCTTTGTCTGGACGCTTCGACATGTTTGTGAGGTTCATGGGAAACTTTGAGAAGACGTGT
CTCATTCCAAATCTGAACGTGAAGCTGGTCATTCTGCTTTTCAATTCTGACTCTAACCCCGACA
AGGCCAAGCAGGTCGAGCTGATGCGAGATTACCGAGTCAAGTACCCGAAGGCTGACATGCAAGT
TTTGCCTGTGTCTGGAGGGTTTTCGAGAGCACTGGCCCTAGAAGTAGGCTCTTCGCAGTTTAGT
AATGAGTCTCTGCTCTTCTTCTGTGATGTGGACCTGGTGTTTACAGCGGAGTTCCTGCAGAGGT
GCCGAGCCAACACTGTGCTGGGCCAGCAGATCTACTTCCCAATCATCTTTAGCCAGTACGATCC
AAAGATTGTCTATAGTGGGAAGGTTCCCAGTGACAACCATTTTGCCTTTACTCAAAAAACCGGC
TTCTGGAGAAACTATGGGTTTGGCATTACTTGTATCTATAAGGGAGATCTTGTCAGAGTGGGAG
GCTTCGATGTCTCCATCCAGGGCTGGGGGCTGGAGGATGTGGACCTCTTTAACAAGGTCGTCCA
GGCAGGATTGAAGACATTCCGGAGCCAGGAGGTCGGGGTTGTTCACGTCCACCACCCTGTCTTC
TGTGACCCGAATCTGGACCCCAAGCAGTATAAAATGTGCCTGGGGTCGAAGGCGTCAACATTCG
GGTCCACACAGCAGTTGGCTGAAATGTGGCTGGAGAAGAATGACCCCAGTTACAGCAGAGGCGG
CAACGGCTCGGCCAGGACAGTCTGATTCCGGCCCGCTGCGAAGGACAGTTTTAATTGCCTAATT
TATTTTTAAAAAATTTTTGTATAATCAGTTTTTGAAGTCCGTACAAGGATATATTTTCCAAGTG
GTTTTCTTACACAGGACTCCTTTAAGATTGAGCTTTTTGAACAAAAATGTGATCAATGTTTGCC
TTTGAACACACCTTGCTGAACACTATGTAGCACCGGCTTAGTCCTGACTTGAAGCCCACCCAAT
GAGCAAAACTTTTCTATAAGAATTTTTTGGTCTTTGGTTTTTACATTTCTTTTCCAGACAACTC
CCCTTTTTCTCTCTAGTCCTAAGGCAGAAAAAACGTGAACATTCCTAAGAAGTATTATCGTGAT
AAGAACACTGTAACCCTGGTGGATGTCCTGTTGAGACTGTTGACCTGTCTCTGGTAAATGTCCT
GTTGTGACTGTTAACCTGTTGCCTTTGCACAAATTCTACCTTTTTCCTGTTTTTTTTTTTAAAC
AGTTTGGTTTTTTTTTTTAAAGCCATCCTGAGTTCCAGTCACAAAGTAAAGAGATGTGATAGTG
GTTGTATTGTCATTCTCTCCAGGAGAGCCTTCCAAATCAGATTACTTCCCCGCTGTGCTCCACC
CCCCACTGTCACAGGTTTTTCCCACCCAGCCCGTGGTGGGTGGGGGATGGAGGAAGGCACGCAT
GTGCTGACCCCTCTCTAATCCTGCGACCCAGACGGACCTGGCACTGAAGTCCAAGAAGGACTCG
GCATTTTCTCTGCCCCGCCCTTCTCTGTAGAGGGTACAGTATTATTAGGGTGACAAAGAACGGC
TGGTAGCAGTGGAATGAATGCAAGCTTACAGACAAACCCCTGATGGACGTGTGAGGGAAGTTGG
CGCTTTGTTCTCTGTCCTGTGTTGTGGATGGAGATGACTGCTCCATTTTTTAATTACTGGTTTT
TCTATCTTGTTATCTGCAATACCTTTAATTTATTTAATACCATTGTTTAGATCTCTGCCATTTT
GAGTACTTGTCAGTCACTAGTATTTATGTGTACCATGAGTGTGGTTAGAACGTTTTATTTGCAG
TAAACTGATCTCCAAAGATTTCCTTTTGAAAACACTTTTCCCTCATCCTTAATTTTTACATTCC
CGTCTTACTAAAGATTAAGTGTTCTTTGATAATTTTGGTGCTCATGTGTTTTGGGGACAAAGGT
GAAATGAGTCTGTTGTTATACCAGAGTGTTTGTTTTCAACTTACAGATCCAATGTGCCTTAATA
ATTTGTTTTCATTTAGAGTTCAGACAGTTGATAGAGTTGCCATTTTTAATATACATCATTGGAG
ATCTGCTTATCTGTAAATAGCCTGTTGCACATCCGAACAAATAAAC

hide sequence

RefSeq Acc Id:

XM_039105374 ⟹ XP_038961302

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	129,142,047 - 129,161,167 (+)	NCBI
mRatBN7.2	1	119,731,589 - 119,750,711 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099738	(Get FASTA)	NCBI Sequence Viewer
	XP_038961302	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM08427	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000016939
	ENSRNOP00000016939.6

RefSeq Acc Id:	NP_001099738 ⟸ NM_001106268
- Peptide Label:	precursor
- UniProtKB:	D3ZRM3 (UniProtKB/TrEMBL), A6JBQ0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLGLVLGFVLASRLVLPRASELKRVGPRRRPNPEGCRPGQAASQPGGAPGDARGAQLWPQGSA AEGVPRDRNFLFVGVMTAQKYLQTRAVAAYRTWSKTIPGKVEFFSSEGSDTSIPIPVVPLRGVD DSYPPQKKSFMMLKYMHDHYLDKYEWFMRADDDVYIKGDRLESFLRSLNSSEPLFLGQTGLGTT EEMGKLALEPGENFCMGGPGVILSREVLRRMAPHIGKCLREMYTTHEDVEVGRCVRRFAGVQCV WSYEMQQLFYENYEQNKKGYIRDLHSSKIHRAITLHPNKNPPYQYRLHSYMLSRKIAELRHRTI QLHREIVLMSKYSSTEIQKEDLQLGIPPSFMRFQARQREEILEWEFLTGKYLYSATEGQPPRRG MDSAQREALDDIVLQVMEMINANAKTRGRIIDFKEIQYGYRRVNPMYGAEYILDLLLLYKKHKG KKMTVPVRRHAYLQQTFSKIQFVEHEGLDAQELADRINQDSGSLSFLSNSLKKLVPFQLPGSKM EHKEPKEKKINILIPLSGRFDMFVRFMGNFEKTCLIPNLNVKLVILLFNSDSNPDKAKQVELMR DYRVKYPKADMQVLPVSGGFSRALALEVGSSQFSNESLLFFCDVDLVFTAEFLQRCRANTVLGQ QIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGGFDVSIQGW GLEDVDLFNKVVQAGLKTFRSQEVGVVHVHHPVFCDPNLDPKQYKMCLGSKASTFGSTQQLAEM WLEKNDPSYSRGGNGSARTV hide sequence

Ensembl Acc Id:

ENSRNOP00000016939 ⟸ ENSRNOT00000016939

RefSeq Acc Id:	XP_038961302 ⟸ XM_039105374
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZRM3-F1-model_v2	AlphaFold	D3ZRM3	1-788	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311904	AgrOrtholog
BioCyc Gene	G2FUF-59017	BioCyc
Ensembl Genes	ENSRNOG00000012698	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000016939	ENTREZGENE
	ENSRNOT00000016939.7	UniProtKB/TrEMBL
Gene3D-CATH	3.90.550.50	UniProtKB/TrEMBL
	Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A	UniProtKB/TrEMBL
InterPro	Chond_GalNAc	UniProtKB/TrEMBL
	CS_glycosyltransferase	UniProtKB/TrEMBL
	Nucleotide-diphossugar_trans	UniProtKB/TrEMBL
KEGG Report	rno:292999	UniProtKB/TrEMBL
NCBI Gene	292999	ENTREZGENE
PANTHER	CHONDROITIN SULFATE SYNTHASE 1	UniProtKB/TrEMBL
	CHONDROITIN SYNTHASE	UniProtKB/TrEMBL
Pfam	CHGN	UniProtKB/TrEMBL
PhenoGen	Chsy1	PhenoGen
RatGTEx	ENSRNOG00000012698	RatGTEx
Superfamily-SCOP	SSF53448	UniProtKB/TrEMBL
UniProt	A6JBQ0	ENTREZGENE, UniProtKB/TrEMBL
	D3ZRM3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-18	Chsy1	chondroitin sulfate synthase 1	Chsy1_predicted	carbohydrate (chondroitin) synthase 1 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Chsy1_predicted	carbohydrate (chondroitin) synthase 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)