C16h19orf44 (similar to human chromosome 19 open reading frame 44) - Rat Genome Database

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Gene: C16h19orf44 (similar to human chromosome 19 open reading frame 44) Rattus norvegicus
Analyze
Symbol: C16h19orf44
Name: similar to human chromosome 19 open reading frame 44
RGD ID: 1311847
Description: Orthologous to human C19orf44 (chromosome 19 open reading frame 44); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; cadmium dichloride; gentamycin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical protein LOC290615; LOC290615; RGD1311847; similar to 1700030K09Rik protein; uncharacterized protein C19orf44 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21617,379,999 - 17,396,088 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1617,380,003 - 17,396,002 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1617,448,533 - 17,464,527 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,579,685 - 18,595,699 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01617,501,453 - 17,517,447 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01619,081,329 - 19,097,329 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1619,081,333 - 19,097,329 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01618,944,080 - 18,960,080 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41617,798,175 - 17,814,175 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11617,798,173 - 17,814,173 (-)NCBI
Celera1617,599,777 - 17,615,780 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data
C16h19orf44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21617,379,999 - 17,396,088 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1617,380,003 - 17,396,002 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1617,448,533 - 17,464,527 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,579,685 - 18,595,699 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01617,501,453 - 17,517,447 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01619,081,329 - 19,097,329 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1619,081,333 - 19,097,329 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01618,944,080 - 18,960,080 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41617,798,175 - 17,814,175 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11617,798,173 - 17,814,173 (-)NCBI
Celera1617,599,777 - 17,615,780 (-)NCBICelera
Cytogenetic Map16p14NCBI
C19orf44
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381916,496,394 - 16,521,352 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1916,496,394 - 16,521,352 (+)EnsemblGRCh38hg38GRCh38
GRCh371916,607,205 - 16,632,163 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361916,468,205 - 16,493,163 (+)NCBINCBI36Build 36hg18NCBI36
Celera1916,509,042 - 16,534,003 (+)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1916,175,706 - 16,200,749 (+)NCBIHuRef
CHM1_11916,606,686 - 16,631,648 (+)NCBICHM1_1
T2T-CHM13v2.01916,631,180 - 16,656,141 (+)NCBIT2T-CHM13v2.0
1700030K09Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39873,197,724 - 73,214,385 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl873,197,724 - 73,214,845 (+)EnsemblGRCm39 Ensembl
GRCm38872,443,880 - 72,460,541 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl872,443,880 - 72,461,001 (+)EnsemblGRCm38mm10GRCm38
MGSCv37874,967,779 - 74,984,440 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36875,372,915 - 75,389,530 (+)NCBIMGSCv36mm8
Celera876,782,393 - 76,803,189 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map835.08NCBI
LOC102026345
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555241,235,137 - 1,245,526 (-)NCBIChiLan1.0ChiLan1.0
C19H19orf44
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11920,375,015 - 20,400,180 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01915,986,955 - 16,011,991 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11916,965,343 - 16,991,670 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1916,970,877 - 16,987,604 (+)Ensemblpanpan1.1panPan2
C20H19orf44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12046,019,750 - 46,039,201 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2046,020,441 - 46,037,713 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2045,933,824 - 45,953,374 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02046,507,333 - 46,526,860 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2046,507,340 - 46,526,419 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12045,742,522 - 45,762,020 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02046,153,286 - 46,172,813 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02046,428,598 - 46,448,362 (-)NCBIUU_Cfam_GSD_1.0
CUNH19orf44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118204,545,718 - 204,571,073 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365964,092,974 - 4,120,153 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365964,095,441 - 4,120,127 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C2H19orf44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl261,081,452 - 61,105,091 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1261,076,623 - 61,105,142 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2260,664,710 - 60,674,792 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH19orf44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1615,007,289 - 15,028,062 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660744,440,248 - 4,464,753 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH19orf44
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624908937,199 - 949,594 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C16h19orf44
54 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:205
Count of miRNA genes:147
Interacting mature miRNAs:164
Transcripts:ENSRNOT00000030617
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16422773017696785Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat

Markers in Region
RH128504  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21617,379,749 - 17,379,937 (+)MAPPERmRatBN7.2
Rnor_6.01619,081,080 - 19,081,267NCBIRnor6.0
Rnor_5.01618,943,831 - 18,944,018UniSTSRnor5.0
RGSC_v3.41617,797,926 - 17,798,113UniSTSRGSC3.4
Celera1617,599,528 - 17,599,715UniSTS
RH 3.4 Map16213.62UniSTS
Cytogenetic Map16p14UniSTS
AI713000  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21617,380,235 - 17,380,425 (+)MAPPERmRatBN7.2
Rnor_6.01619,081,566 - 19,081,755NCBIRnor6.0
Rnor_5.01618,944,317 - 18,944,506UniSTSRnor5.0
RGSC_v3.41617,798,412 - 17,798,601UniSTSRGSC3.4
Celera1617,600,014 - 17,600,203UniSTS
Cytogenetic Map16p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 26 19 6 14 6 2 63 32 41 11
Low 3 17 38 35 5 35 8 9 11 3 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000030617   ⟹   ENSRNOP00000032342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1617,380,003 - 17,396,002 (-)Ensembl
Rnor_6.0 Ensembl1619,081,333 - 19,097,329 (-)Ensembl
RefSeq Acc Id: NM_001013879   ⟹   NP_001013901
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21617,379,999 - 17,396,002 (-)NCBI
Rnor_6.01619,081,329 - 19,097,329 (-)NCBI
Rnor_5.01618,944,080 - 18,960,080 (-)NCBI
RGSC_v3.41617,798,175 - 17,814,175 (-)RGD
Celera1617,599,777 - 17,615,780 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252799   ⟹   XP_006252861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21617,380,098 - 17,396,049 (-)NCBI
Rnor_6.01619,081,428 - 19,097,265 (-)NCBI
Rnor_5.01618,944,080 - 18,960,080 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094275   ⟹   XP_038950203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21617,380,098 - 17,396,088 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001013901   ⟸   NM_001013879
- UniProtKB: Q6AXP1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006252861   ⟸   XM_006252799
- Peptide Label: isoform X1
- UniProtKB: Q6AXP1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000032342   ⟸   ENSRNOT00000030617
RefSeq Acc Id: XP_038950203   ⟸   XM_039094275
- Peptide Label: isoform X2
- UniProtKB: A0A8L2UKS5 (UniProtKB/TrEMBL)
Protein Domains
DUF4614

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXP1-F1-model_v2 AlphaFold Q6AXP1 1-624 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699983
Promoter ID:EPDNEW_R10505
Type:initiation region
Name:RGD1311847_1
Description:similar to 1700030K09Rik protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01619,097,351 - 19,097,411EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311847 AgrOrtholog
BioCyc Gene G2FUF-11884 BioCyc
Ensembl Genes ENSRNOG00000023700 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030617 ENTREZGENE
  ENSRNOT00000030617.4 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7114707 IMAGE-MGC_LOAD
InterPro C19orf44-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF4614 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:290615 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94976 IMAGE-MGC_LOAD
NCBI Gene 290615 ENTREZGENE
PANTHER DUF4614 DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF4614 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen C16h19orf44 PhenoGen
RatGTEx ENSRNOG00000023700 RatGTEx
UniProt A0A8L2UKS5 ENTREZGENE, UniProtKB/TrEMBL
  CS044_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-27 C16h19orf44  similar to human chromosome 19 open reading frame 44  RGD1311847  similar to 1700030K09Rik protein  Name and Symbol changed 629549 APPROVED
2005-12-06 RGD1311847  similar to 1700030K09Rik protein  RGD1311847_predicted  similar to 1700030K09Rik protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311847_predicted  similar to 1700030K09Rik protein (predicted)  LOC290615_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC290615_predicted  similar to 1700030K09Rik protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL