Rhbdd3 (rhomboid domain containing 3) - Rat Genome Database

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Gene: Rhbdd3 (rhomboid domain containing 3) Rattus norvegicus
Analyze
Symbol: Rhbdd3
Name: rhomboid domain containing 3
RGD ID: 1311827
Description: Predicted to enable serine-type endopeptidase activity. Predicted to act upstream of or within several processes, including MAPK cascade; negative regulation of natural killer cell activation; and positive regulation of protein catabolic process. Predicted to be located in membrane. Orthologous to human RHBDD3 (rhomboid domain containing 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC289753; RGD1311827; rhomboid domain-containing protein 3; similar to RIKEN cDNA 5730411O18 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,208,155 - 84,214,334 (+)NCBIGRCr8
mRatBN7.21479,994,111 - 80,000,294 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1479,994,158 - 80,000,175 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1484,396,786 - 84,402,453 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01485,636,868 - 85,642,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,086,211 - 82,091,878 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01485,350,852 - 85,357,029 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,351,358 - 85,357,023 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,028,602 - 86,034,643 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41485,759,530 - 85,765,197 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11485,778,674 - 85,784,340 (+)NCBI
Celera1478,884,939 - 78,890,606 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:23610400  


Genomics

Comparative Map Data
Rhbdd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,208,155 - 84,214,334 (+)NCBIGRCr8
mRatBN7.21479,994,111 - 80,000,294 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1479,994,158 - 80,000,175 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1484,396,786 - 84,402,453 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01485,636,868 - 85,642,535 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,086,211 - 82,091,878 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01485,350,852 - 85,357,029 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,351,358 - 85,357,023 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,028,602 - 86,034,643 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41485,759,530 - 85,765,197 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11485,778,674 - 85,784,340 (+)NCBI
Celera1478,884,939 - 78,890,606 (+)NCBICelera
Cytogenetic Map14q21NCBI
RHBDD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382229,259,852 - 29,268,163 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2229,259,872 - 29,268,209 (-)EnsemblGRCh38hg38GRCh38
GRCh372229,655,841 - 29,664,152 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362227,985,844 - 27,993,914 (-)NCBINCBI36Build 36hg18NCBI36
Build 342227,980,397 - 27,988,468NCBI
Celera2213,455,708 - 13,463,777 (-)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2212,620,186 - 12,628,257 (-)NCBIHuRef
CHM1_12229,615,142 - 29,623,212 (-)NCBICHM1_1
T2T-CHM13v2.02229,723,344 - 29,731,654 (-)NCBIT2T-CHM13v2.0
Rhbdd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,048,282 - 5,056,100 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,048,926 - 5,056,093 (+)EnsemblGRCm39 Ensembl
GRCm38115,098,282 - 5,106,100 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,098,926 - 5,106,093 (+)EnsemblGRCm38mm10GRCm38
MGSCv37114,999,441 - 5,006,094 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36114,999,441 - 5,006,094 (+)NCBIMGSCv36mm8
Celera115,596,534 - 5,603,187 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.26NCBI
Rhbdd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554553,564,867 - 3,570,798 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554553,564,867 - 3,570,910 (-)NCBIChiLan1.0ChiLan1.0
RHBDD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22339,243,611 - 39,251,986 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12241,944,116 - 41,952,472 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02210,315,438 - 10,323,803 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12228,123,098 - 28,131,278 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2228,123,115 - 28,131,090 (-)Ensemblpanpan1.1panPan2
RHBDD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12622,573,260 - 22,578,921 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2622,573,316 - 22,577,683 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2622,445,265 - 22,451,052 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02622,947,261 - 22,953,053 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2622,947,263 - 22,952,477 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12622,656,257 - 22,662,047 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02622,920,395 - 22,926,188 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02622,984,609 - 22,990,398 (-)NCBIUU_Cfam_GSD_1.0
Rhbdd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118112,574,283 - 112,580,023 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366573,290,574 - 3,296,705 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366573,290,684 - 3,296,352 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RHBDD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1446,400,026 - 46,408,364 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11446,403,146 - 46,411,217 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21449,367,986 - 49,373,715 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RHBDD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11912,130,500 - 12,138,210 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1912,125,828 - 12,138,761 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045114,011,966 - 114,019,721 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rhbdd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247475,641,855 - 5,647,122 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247475,641,702 - 5,647,808 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rhbdd3
29 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:53
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000031914
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat

Markers in Region
RH129907  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,000,486 - 80,000,668 (+)MAPPERmRatBN7.2
Rnor_6.01485,357,222 - 85,357,403NCBIRnor6.0
Rnor_5.01486,034,840 - 86,035,021UniSTSRnor5.0
RGSC_v3.41485,765,394 - 85,765,575UniSTSRGSC3.4
Celera1478,890,803 - 78,890,984UniSTS
RH 3.4 Map14565.6UniSTS
Cytogenetic Map14q21UniSTS
RH137079  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2660,008,927 - 60,009,091 (+)MAPPERmRatBN7.2
mRatBN7.21480,000,061 - 80,000,225 (-)MAPPERmRatBN7.2
mRatBN7.2660,008,927 - 60,009,091 (-)MAPPERmRatBN7.2
mRatBN7.21480,000,061 - 80,000,225 (+)MAPPERmRatBN7.2
Rnor_6.0662,923,026 - 62,923,189NCBIRnor6.0
Rnor_6.01485,356,797 - 85,356,960NCBIRnor6.0
Rnor_5.01486,034,415 - 86,034,578UniSTSRnor5.0
Rnor_5.0672,511,874 - 72,512,037UniSTSRnor5.0
RGSC_v3.4662,217,609 - 62,217,772UniSTSRGSC3.4
RGSC_v3.41485,764,969 - 85,765,132UniSTSRGSC3.4
Celera1478,890,378 - 78,890,541UniSTS
Celera659,018,734 - 59,018,897UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000031914   ⟹   ENSRNOP00000032424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1479,994,158 - 80,000,175 (+)Ensembl
Rnor_6.0 Ensembl1485,351,358 - 85,357,023 (+)Ensembl
RefSeq Acc Id: NM_001013875   ⟹   NP_001013897
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,667 - 84,214,334 (+)NCBI
mRatBN7.21479,994,623 - 80,000,290 (+)NCBI
Rnor_6.01485,351,358 - 85,357,025 (+)NCBI
Rnor_5.01486,028,602 - 86,034,643 (+)NCBI
RGSC_v3.41485,759,530 - 85,765,197 (+)RGD
Celera1478,884,939 - 78,890,606 (+)RGD
Sequence:
RefSeq Acc Id: XM_006251204   ⟹   XP_006251266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,456 - 84,214,334 (+)NCBI
mRatBN7.21479,994,363 - 80,000,294 (+)NCBI
Rnor_6.01485,351,078 - 85,357,029 (+)NCBI
Rnor_5.01486,028,602 - 86,034,643 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251205   ⟹   XP_006251267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,229 - 84,214,334 (+)NCBI
mRatBN7.21479,994,185 - 80,000,290 (+)NCBI
Rnor_6.01485,350,969 - 85,357,029 (+)NCBI
Rnor_5.01486,028,602 - 86,034,643 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251206   ⟹   XP_006251268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,530 - 84,214,334 (+)NCBI
mRatBN7.21479,994,363 - 80,000,294 (+)NCBI
Rnor_6.01485,351,313 - 85,357,029 (+)NCBI
Rnor_5.01486,028,602 - 86,034,643 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251207   ⟹   XP_006251269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,155 - 84,214,334 (+)NCBI
mRatBN7.21479,994,111 - 80,000,290 (+)NCBI
Rnor_6.01485,350,852 - 85,357,029 (+)NCBI
Rnor_5.01486,028,602 - 86,034,643 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251208   ⟹   XP_006251270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,400 - 84,214,334 (+)NCBI
mRatBN7.21479,994,356 - 80,000,294 (+)NCBI
Rnor_6.01485,351,078 - 85,357,029 (+)NCBI
Rnor_5.01486,028,602 - 86,034,643 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091738   ⟹   XP_038947666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,456 - 84,214,334 (+)NCBI
mRatBN7.21479,994,363 - 80,000,294 (+)NCBI
RefSeq Acc Id: XM_039091740   ⟹   XP_038947668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,403 - 84,214,334 (+)NCBI
mRatBN7.21479,994,356 - 80,000,294 (+)NCBI
RefSeq Acc Id: XM_063272948   ⟹   XP_063129018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,167 - 84,214,334 (+)NCBI
RefSeq Acc Id: XM_063272949   ⟹   XP_063129019
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,208,530 - 84,213,563 (+)NCBI
RefSeq Acc Id: NP_001013897   ⟸   NM_001013875
- UniProtKB: Q642B3 (UniProtKB/Swiss-Prot),   A6IKK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251267   ⟸   XM_006251205
- Peptide Label: isoform X1
- UniProtKB: Q642B3 (UniProtKB/Swiss-Prot),   A6IKK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251269   ⟸   XM_006251207
- Peptide Label: isoform X1
- UniProtKB: Q642B3 (UniProtKB/Swiss-Prot),   A6IKK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251266   ⟸   XM_006251204
- Peptide Label: isoform X1
- UniProtKB: Q642B3 (UniProtKB/Swiss-Prot),   A6IKK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251270   ⟸   XM_006251208
- Peptide Label: isoform X1
- UniProtKB: Q642B3 (UniProtKB/Swiss-Prot),   A6IKK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251268   ⟸   XM_006251206
- Peptide Label: isoform X1
- UniProtKB: Q642B3 (UniProtKB/Swiss-Prot),   A6IKK8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000032424   ⟸   ENSRNOT00000031914
RefSeq Acc Id: XP_038947668   ⟸   XM_039091740
- Peptide Label: isoform X1
- UniProtKB: Q642B3 (UniProtKB/Swiss-Prot),   A6IKK8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947666   ⟸   XM_039091738
- Peptide Label: isoform X1
- UniProtKB: Q642B3 (UniProtKB/Swiss-Prot),   A6IKK8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129018   ⟸   XM_063272948
- Peptide Label: isoform X1
- UniProtKB: Q642B3 (UniProtKB/Swiss-Prot),   A6IKK8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129019   ⟸   XM_063272949
- Peptide Label: isoform X2
- UniProtKB: A6IKK9 (UniProtKB/TrEMBL)
Protein Domains
Peptidase S54 rhomboid   UBA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q642B3-F1-model_v2 AlphaFold Q642B3 1-385 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699455
Promoter ID:EPDNEW_R9979
Type:initiation region
Name:Rhbdd3_1
Description:rhomboid domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01485,351,406 - 85,351,466EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311827 AgrOrtholog
BioCyc Gene G2FUF-15148 BioCyc
Ensembl Genes ENSRNOG00000027032 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000031914 ENTREZGENE
  ENSRNOT00000031914.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1540.10 UniProtKB/Swiss-Prot
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhomboid-like UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7112018 IMAGE-MGC_LOAD
InterPro Peptidase_S54_rhomboid_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rhomboid-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:289753 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93864 IMAGE-MGC_LOAD
NCBI Gene 289753 ENTREZGENE
PANTHER PTHR43066:SF16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHOMBOID-RELATED PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Rhomboid UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rhbdd3 PhenoGen
RatGTEx ENSRNOG00000027032 RatGTEx
Superfamily-SCOP Rhomboid-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  SSF46934 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6IKK8 ENTREZGENE, UniProtKB/TrEMBL
  A6IKK9 ENTREZGENE, UniProtKB/TrEMBL
  Q642B3 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-27 Rhbdd3  rhomboid domain containing 3  RGD1311827  similar to RIKEN cDNA 5730411O18 gene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1311827  similar to RIKEN cDNA 5730411O18 gene  RGD1311827_predicted  similar to RIKEN cDNA 5730411O18 gene (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311827_predicted  similar to RIKEN cDNA 5730411O18 gene (predicted)  LOC289753_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC289753_predicted  similar to RIKEN cDNA 5730411O18 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL