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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dtd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of DTD1 mRNA | CTD | PMID:22298810 | Dtd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DTD1 mRNA | CTD | PMID:33387578 | Dtd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dtd1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DTD1 mRNA | CTD | PMID:21570461 | Dtd1 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DTD1 mRNA | CTD | PMID:30851411 | Dtd1 | Rat | 3H-1,2-dithiole-3-thione | increases expression | EXP | | 6480464 | 1 and 2-dithiol-3-thione results in increased expression of DTD1 mRNA | CTD | PMID:19162173 | Dtd1 | Rat | aflatoxin B1 | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of DTD1 mRNA | CTD | PMID:21641981 | Dtd1 | Rat | aflatoxin B1 | increases methylation | ISO | DTD1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of DTD1 intron | CTD | PMID:30157460 | Dtd1 | Rat | all-trans-retinoic acid | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DTD1 mRNA | CTD | PMID:33167477 | Dtd1 | Rat | aristolochic acid A | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of DTD1 mRNA | CTD | PMID:33212167 | Dtd1 | Rat | arsenite(3-) | multiple interactions | ISO | DTD1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to DTD1 mRNA] | CTD | PMID:32406909 | Dtd1 | Rat | benzo[a]pyrene | decreases expression | ISO | Dtd1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of DTD1 mRNA | CTD | PMID:21715664 | Dtd1 | Rat | benzo[a]pyrene | affects methylation | ISO | DTD1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of DTD1 intron | CTD | PMID:30157460 | Dtd1 | Rat | benzo[a]pyrene | decreases methylation | ISO | DTD1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of DTD1 promoter | CTD | PMID:27901495 | Dtd1 | Rat | benzo[a]pyrene | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of DTD1 mRNA | CTD | PMID:21632981 | Dtd1 | Rat | benzo[a]pyrene | increases expression | ISO | Dtd1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of DTD1 mRNA | CTD | PMID:22228805 | Dtd1 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | Dtd1 | Rat | bisphenol A | decreases expression | ISO | Dtd1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of DTD1 mRNA | CTD | PMID:26063408 and PMID:33221593 | Dtd1 | Rat | bisphenol A | multiple interactions | ISO | DTD1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of DTD1 gene | CTD | PMID:31601247 | Dtd1 | Rat | bisphenol A | affects expression | ISO | DTD1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of DTD1 mRNA | CTD | PMID:30903817 | Dtd1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DTD1 mRNA | CTD | PMID:30816183 | Dtd1 | Rat | caffeine | decreases phosphorylation | ISO | DTD1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of DTD1 protein | CTD | PMID:35688186 | Dtd1 | Rat | carbon nanotube | decreases expression | ISO | Dtd1 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of DTD1 mRNA | CTD | PMID:25554681 | Dtd1 | Rat | chlorpyrifos | decreases expression | ISO | Dtd1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of DTD1 mRNA | CTD | PMID:37019170 | Dtd1 | Rat | choline | multiple interactions | ISO | Dtd1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DTD1 gene | CTD | PMID:20938992 | Dtd1 | Rat | cisplatin | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of DTD1 mRNA | CTD | PMID:27594783 | Dtd1 | Rat | cyclosporin A | increases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DTD1 mRNA | CTD | PMID:20106945 more ... | Dtd1 | Rat | doxorubicin | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of DTD1 mRNA | CTD | PMID:29803840 | Dtd1 | Rat | ethanol | increases expression | ISO | Dtd1 (Mus musculus) | 6480464 | Ethanol results in increased expression of DTD1 mRNA | CTD | PMID:30319688 | Dtd1 | Rat | ethyl methanesulfonate | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of DTD1 mRNA | CTD | PMID:23649840 | Dtd1 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of DTD1 mRNA | CTD | PMID:24136188 | Dtd1 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of DTD1 mRNA | CTD | PMID:24793618 | Dtd1 | Rat | folic acid | multiple interactions | ISO | Dtd1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DTD1 gene | CTD | PMID:20938992 | Dtd1 | Rat | formaldehyde | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of DTD1 mRNA | CTD | PMID:23649840 | Dtd1 | Rat | fulvestrant | multiple interactions | ISO | DTD1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of DTD1 gene | CTD | PMID:31601247 | Dtd1 | Rat | ivermectin | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DTD1 protein | CTD | PMID:32959892 | Dtd1 | Rat | L-methionine | multiple interactions | ISO | Dtd1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of DTD1 gene | CTD | PMID:20938992 | Dtd1 | Rat | methyl methanesulfonate | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of DTD1 mRNA | CTD | PMID:23649840 | Dtd1 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of DTD1 gene | CTD | PMID:33148267 | Dtd1 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of DTD1 mRNA | CTD | PMID:24136188 | Dtd1 | Rat | nickel sulfate | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of DTD1 mRNA | CTD | PMID:22714537 | Dtd1 | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of DTD1 mRNA | CTD | PMID:24136188 | Dtd1 | Rat | nitrates | multiple interactions | ISO | Dtd1 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of DTD1 mRNA | CTD | PMID:35964746 | Dtd1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DTD1 mRNA | CTD | PMID:25729387 | Dtd1 | Rat | paracetamol | affects expression | ISO | Dtd1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of DTD1 mRNA | CTD | PMID:17562736 | Dtd1 | Rat | paracetamol | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of DTD1 mRNA | CTD | PMID:25704631 | Dtd1 | Rat | parathion | increases expression | ISO | Dtd1 (Mus musculus) | 6480464 | Parathion results in increased expression of DTD1 mRNA | CTD | PMID:34813904 | Dtd1 | Rat | perfluorononanoic acid | increases expression | ISO | DTD1 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of DTD1 mRNA | CTD | PMID:32588087 | Dtd1 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of DTD1 gene | CTD | PMID:33148267 | Dtd1 | Rat | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of DTD1 mRNA | CTD | PMID:19162173 | Dtd1 | Rat | rac-lactic acid | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DTD1 mRNA | CTD | PMID:30851411 | Dtd1 | Rat | SB 431542 | multiple interactions | ISO | DTD1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of DTD1 protein | CTD | PMID:37664457 | Dtd1 | Rat | sodium arsenite | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of DTD1 mRNA | CTD | PMID:22714537 | Dtd1 | Rat | sunitinib | increases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of DTD1 mRNA | CTD | PMID:31533062 | Dtd1 | Rat | temozolomide | increases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of DTD1 mRNA | CTD | PMID:31758290 | Dtd1 | Rat | testosterone | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of DTD1 mRNA | CTD | PMID:33359661 | Dtd1 | Rat | thiram | decreases expression | ISO | DTD1 (Homo sapiens) | 6480464 | Thiram results in decreased expression of DTD1 mRNA | CTD | PMID:38568856 | Dtd1 | Rat | titanium dioxide | decreases methylation | ISO | Dtd1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of DTD1 gene | CTD | PMID:35295148 | Dtd1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DTD1 mRNA | CTD | PMID:25729387 | Dtd1 | Rat | valproic acid | affects expression | ISO | DTD1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DTD1 mRNA | CTD | PMID:25979313 | |