Gfi1b (growth factor independent 1B transcriptional repressor) - Rat Genome Database

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Gene: Gfi1b (growth factor independent 1B transcriptional repressor) Rattus norvegicus
Analyze
Symbol: Gfi1b
Name: growth factor independent 1B transcriptional repressor
RGD ID: 1311727
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of granulocyte differentiation; and regulation of erythrocyte differentiation. Predicted to be located in nuclear matrix; nucleoplasm; and plasma membrane. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in gray platelet syndrome and platelet-type bleeding disorder 17. Orthologous to human GFI1B (growth factor independent 1B transcriptional repressor); INTERACTS WITH bisphenol A; cadmium dichloride; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: growth factor independent 1B; growth factor independent 1B transcription repressor; LOC311832; zinc finger protein Gfi-1b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,338,213 - 32,350,963 (-)NCBIGRCr8
mRatBN7.2311,940,232 - 11,952,989 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,940,233 - 11,952,942 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx315,012,664 - 15,025,303 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,597,615 - 23,610,254 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,852,075 - 21,864,709 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,190,721 - 7,203,444 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,190,722 - 7,203,420 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,540,994 - 12,553,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,598,772 - 7,611,402 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,599,577 - 7,605,032 (-)NCBI
Celera36,721,072 - 6,733,683 (-)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nuclear matrix  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
plasma membrane  (IEA,ISO)
transcription regulator complex  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Growth factor-independent 1B gene (GFI1B) is overexpressed in erythropoietic and megakaryocytic malignancies and increases their proliferation rate. Elmaagacli AH, etal., Br J Haematol. 2007 Jan;136(2):212-9. Epub 2006 Dec 8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. A dominant-negative GFI1B mutation in the gray platelet syndrome. Monteferrario D, etal., N Engl J Med. 2014 Jan 16;370(3):245-53. doi: 10.1056/NEJMoa1308130. Epub 2013 Dec 10.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia. Vassen L, etal., Int J Hematol. 2009 May;89(4):422-30. doi: 10.1007/s12185-009-0286-5. Epub 2009 Apr 10.
Additional References at PubMed
PMID:9566867   PMID:12477932   PMID:12874834   PMID:15920471   PMID:17707228  


Genomics

Comparative Map Data
Gfi1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,338,213 - 32,350,963 (-)NCBIGRCr8
mRatBN7.2311,940,232 - 11,952,989 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,940,233 - 11,952,942 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx315,012,664 - 15,025,303 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,597,615 - 23,610,254 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,852,075 - 21,864,709 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,190,721 - 7,203,444 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,190,722 - 7,203,420 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,540,994 - 12,553,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,598,772 - 7,611,402 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,599,577 - 7,605,032 (-)NCBI
Celera36,721,072 - 6,733,683 (-)NCBICelera
Cytogenetic Map3p12NCBI
GFI1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389132,945,531 - 132,993,434 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9132,944,000 - 132,991,687 (+)EnsemblGRCh38hg38GRCh38
GRCh379135,820,918 - 135,867,074 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,843,919 - 134,856,903 (+)NCBINCBI36Build 36hg18NCBI36
Build 349132,883,651 - 132,896,636NCBI
Celera9106,395,838 - 106,408,823 (+)NCBICelera
Cytogenetic Map9q34.13NCBI
HuRef9105,347,908 - 105,360,763 (+)NCBIHuRef
CHM1_19136,004,426 - 136,017,406 (+)NCBICHM1_1
T2T-CHM13v2.09145,157,346 - 145,209,367 (+)NCBIT2T-CHM13v2.0
Gfi1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39228,499,462 - 28,511,994 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl228,499,462 - 28,511,994 (-)EnsemblGRCm39 Ensembl
GRCm38228,609,450 - 28,621,982 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl228,609,450 - 28,621,982 (-)EnsemblGRCm38mm10GRCm38
MGSCv37228,464,970 - 28,477,502 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36228,431,466 - 28,443,953 (-)NCBIMGSCv36mm8
Celera228,313,956 - 28,326,488 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
Gfi1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555132,277,981 - 2,281,515 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555132,273,267 - 2,281,850 (+)NCBIChiLan1.0ChiLan1.0
GFI1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,363,078 - 6,376,517 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan196,365,415 - 6,378,854 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09104,061,236 - 104,113,208 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19132,692,343 - 132,742,326 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9132,692,343 - 132,742,326 (+)Ensemblpanpan1.1panPan2
GFI1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1951,380,697 - 51,394,679 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl951,380,696 - 51,392,812 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,643,918 - 50,674,158 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0952,273,983 - 52,304,414 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl952,273,980 - 52,278,963 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1951,052,489 - 51,082,796 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0951,376,978 - 51,407,295 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0951,456,418 - 51,486,732 (-)NCBIUU_Cfam_GSD_1.0
Gfi1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947199,639,690 - 199,649,460 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648719,414,135 - 19,417,465 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648719,414,135 - 19,417,465 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GFI1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1272,702,184 - 272,715,539 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11272,701,386 - 272,715,551 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21306,852,829 - 306,866,368 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GFI1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1125,145,194 - 5,158,659 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl125,145,844 - 5,150,274 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607910,500,764 - 10,505,862 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gfi1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247603,446,028 - 3,454,818 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247603,446,028 - 3,454,818 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gfi1b
98 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:301
Count of miRNA genes:190
Interacting mature miRNAs:218
Transcripts:ENSRNOT00000015236
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3612543751125437Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat

Markers in Region
RH143268  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2311,940,304 - 11,940,419 (+)MAPPERmRatBN7.2
Rnor_6.037,190,794 - 7,190,908NCBIRnor6.0
Rnor_5.0312,541,067 - 12,541,181UniSTSRnor5.0
RGSC_v3.437,598,791 - 7,598,905UniSTSRGSC3.4
Celera36,721,091 - 6,721,205UniSTS
RH 3.4 Map321.9UniSTS
Cytogenetic Map3p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 1 41 70 70 73 47 21 47 6 170 78 53 36 50 26

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC129847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC158685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000015236   ⟹   ENSRNOP00000015236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl311,940,233 - 11,952,942 (-)Ensembl
Rnor_6.0 Ensembl37,190,722 - 7,203,420 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078428   ⟹   ENSRNOP00000070622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl37,190,726 - 7,202,848 (-)Ensembl
RefSeq Acc Id: NM_001107823   ⟹   NP_001101293
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,267 - 32,350,901 (-)NCBI
mRatBN7.2311,940,286 - 11,952,927 (-)NCBI
Rnor_6.037,190,775 - 7,203,405 (-)NCBI
Rnor_5.0312,540,994 - 12,553,716 (-)NCBI
RGSC_v3.437,598,772 - 7,611,402 (-)RGD
Celera36,721,072 - 6,733,683 (-)RGD
Sequence:
RefSeq Acc Id: XM_006233789   ⟹   XP_006233851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,963 (-)NCBI
mRatBN7.2311,940,232 - 11,952,988 (-)NCBI
Rnor_6.037,190,721 - 7,203,444 (-)NCBI
Rnor_5.0312,540,994 - 12,553,716 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105213   ⟹   XP_038961141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,951 (-)NCBI
mRatBN7.2311,940,232 - 11,952,986 (-)NCBI
RefSeq Acc Id: XM_039105214   ⟹   XP_038961142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,434 (-)NCBI
mRatBN7.2311,940,232 - 11,952,814 (-)NCBI
RefSeq Acc Id: XM_039105215   ⟹   XP_038961143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,945 (-)NCBI
mRatBN7.2311,940,232 - 11,952,984 (-)NCBI
RefSeq Acc Id: XM_039105216   ⟹   XP_038961144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,346,665 (-)NCBI
mRatBN7.2311,940,232 - 11,948,686 (-)NCBI
RefSeq Acc Id: XM_039105218   ⟹   XP_038961146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,963 (-)NCBI
mRatBN7.2311,940,232 - 11,952,989 (-)NCBI
RefSeq Acc Id: XM_039105219   ⟹   XP_038961147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,346,864 (-)NCBI
mRatBN7.2311,940,232 - 11,948,885 (-)NCBI
RefSeq Acc Id: XM_063283925   ⟹   XP_063139995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,338,213 - 32,350,790 (-)NCBI
RefSeq Acc Id: NP_001101293   ⟸   NM_001107823
- UniProtKB: B0BN50 (UniProtKB/TrEMBL),   D3ZHB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233851   ⟸   XM_006233789
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070622   ⟸   ENSRNOT00000078428
Ensembl Acc Id: ENSRNOP00000015236   ⟸   ENSRNOT00000015236
RefSeq Acc Id: XP_038961146   ⟸   XM_039105218
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961141   ⟸   XM_039105213
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961143   ⟸   XM_039105215
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961142   ⟸   XM_039105214
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961147   ⟸   XM_039105219
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961144   ⟸   XM_039105216
- Peptide Label: isoform X1
- UniProtKB: A0A8J8XL46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139995   ⟸   XM_063283925
- Peptide Label: isoform X2
- UniProtKB: B0BN50 (UniProtKB/TrEMBL),   D3ZHB6 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BN50-F1-model_v2 AlphaFold B0BN50 1-330 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311727 AgrOrtholog
BioCyc Gene G2FUF-50274 BioCyc
Ensembl Genes ENSRNOG00000011353 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015236 ENTREZGENE
  ENSRNOT00000015236.6 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8374780 IMAGE-MGC_LOAD
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:311832 UniProtKB/TrEMBL
MGC_CLONE MGC:187699 IMAGE-MGC_LOAD
NCBI Gene 311832 ENTREZGENE
PANTHER FI21258P1-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 771 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Gfi1b PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011353 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A8J8XL46 ENTREZGENE, UniProtKB/TrEMBL
  B0BN50 ENTREZGENE, UniProtKB/TrEMBL
  D3ZHB6 ENTREZGENE
UniProt Secondary D3ZHB6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-11 Gfi1b  growth factor independent 1B transcriptional repressor  Gfi1b  growth factor independent 1B transcription repressor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-17 Gfi1b  growth factor independent 1B transcription repressor  Gfi1b  growth factor independent 1B   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Gfi1b  growth factor independent 1B   Gfi1b_predicted  growth factor independent 1B (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Gfi1b_predicted  growth factor independent 1B (predicted)      Symbol and Name status set to approved 70820 APPROVED