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Gene: Sec24d (SEC24 homolog D, COPII coat complex component) Rattus norvegicus

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Symbol:

Sec24d

Name:

SEC24 homolog D, COPII coat complex component

RGD ID:

1311720

Description:

Predicted to enable SNARE binding activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading. Predicted to act upstream of or within in utero embryonic development. Predicted to be located in ER to Golgi transport vesicle membrane; cytosol; and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Orthologous to human SEC24D (SEC24 homolog D, COPII coat complex component); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC310843; protein transport protein Sec24D; SEC24 family member D; SEC24 family, member D; SEC24 family, member D (S. cerevisiae); SEC24 related gene family, member D; SEC24 related gene family, member D (S. cerevisiae)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SEC24D (SEC24 homolog D, COPII coat complex component)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Sec24d (SEC24 homolog D, COPII coat complex component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sec24d (SEC24 homolog D, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SEC24D (SEC24 homolog D, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SEC24D (SEC24 homolog D, COPII coat complex component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sec24d (SEC24 homolog D, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SEC24D (SEC24 homolog D, COPII coat complex component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SEC24D (SEC24 homolog D, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sec24d (SEC24 homolog D, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Sec24d (SEC24 homolog D, COPII component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SEC24D (SEC24 homolog D, COPII coat complex component)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SEC24D (SEC24 homolog D, COPII coat complex component)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sec24d (SEC24 homolog D, COPII coat complex component)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sec24d (SEC24 homolog D, COPII coat complex component)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sec24d (SEC24 homolog D, COPII coat complex component)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	sec-24.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	sec-24.1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SFB3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	SFB3	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Sec24CD	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Sec24CD	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	anxa2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sec24d	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sec24d	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	214,103,138 - 214,211,155 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	214,103,190 - 214,211,144 (+)	Ensembl				GRCr8
mRatBN7.2	2	211,418,557 - 211,526,588 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	211,418,623 - 211,526,587 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	219,091,582 - 219,198,356 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	216,991,462 - 217,098,234 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	211,845,703 - 211,952,480 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	227,455,704 - 227,562,801 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	227,455,722 - 227,562,319 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	246,815,650 - 246,919,957 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	219,985,811 - 220,096,797 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	203,833,456 - 203,940,242 (+)	NCBI		Celera
RGSC_v3.1	2	219,950,676 - 220,059,192 (+)	NCBI
Cytogenetic Map	2	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cole-Carpenter syndrome (ISO)

Cole-Carpenter Syndrome 2 (ISO)

Desbuquois dysplasia (ISO)

epilepsy (ISO)

genetic disease (ISO)

osteoporosis-pseudoglioma syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

2-bromohexadecanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

avobenzone (ISO)

Benoxacor (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

beta-naphthoflavone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

bupropion (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) chloride (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

cyproconazole (ISO)

decabromodiphenyl ether (ISO)

Dibutyl phosphate (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

fenthion (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

genistein (ISO)

glyphosate (EXP)

hydroquinone (ISO)

ibogaine (ISO)

iron dichloride (ISO)

ivermectin (ISO)

lead diacetate (ISO)

methapyrilene (EXP)

methidathion (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

methylseleninic acid (ISO)

nefazodone (EXP)

nickel atom (ISO)

nickel subsulfide (EXP)

orlistat (ISO)

oxaliplatin (EXP)

panobinostat (ISO)

paracetamol (EXP,ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

propiconazole (ISO)

quercetin (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichostatin A (ISO)

trovafloxacin (EXP)

tunicamycin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

COPII-coated vesicle cargo loading (IBA,IEA,ISO)

endoplasmic reticulum to Golgi vesicle-mediated transport (IEA,ISO)

in utero embryonic development (IEA,ISO)

intracellular protein transport (IEA)

protein transport (IEA)

vesicle-mediated transport (IEA)

Cellular Component

COPII vesicle coat (IBA,IEA,ISO)

cytoplasmic vesicle (IEA)

cytosol (IEA)

endoplasmic reticulum exit site (IBA)

endoplasmic reticulum membrane (IEA)

ER to Golgi transport vesicle membrane (IEA)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

SNARE binding (IBA,IEA,ISO)

zinc ion binding (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:17499046	PMID:18843296	PMID:20427317	PMID:23596517	PMID:24876386	PMID:28801610

Genomics

Comparative Map Data

Sec24d
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	214,103,138 - 214,211,155 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	214,103,190 - 214,211,144 (+)	Ensembl				GRCr8
mRatBN7.2	2	211,418,557 - 211,526,588 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	211,418,623 - 211,526,587 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	219,091,582 - 219,198,356 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	216,991,462 - 217,098,234 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	211,845,703 - 211,952,480 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	227,455,704 - 227,562,801 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	227,455,722 - 227,562,319 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	246,815,650 - 246,919,957 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	219,985,811 - 220,096,797 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	203,833,456 - 203,940,242 (+)	NCBI		Celera
RGSC_v3.1	2	219,950,676 - 220,059,192 (+)	NCBI
Cytogenetic Map	2	q42	NCBI

SEC24D
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	118,722,823 - 118,836,126 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	118,722,822 - 118,838,683 (-)	Ensembl			hg38	GRCh38
GRCh37	4	119,643,978 - 119,757,281 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	119,863,427 - 119,976,702 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	4	120,001,581 - 120,114,857	NCBI
Celera	4	117,004,529 - 117,117,866 (-)	NCBI		Celera
Cytogenetic Map	4	q26	NCBI
HuRef	4	115,365,531 - 115,479,569 (-)	NCBI		HuRef
CHM1_1	4	119,619,921 - 119,733,840 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	122,028,139 - 122,141,474 (-)	NCBI		T2T-CHM13v2.0

Sec24d
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	123,058,451 - 123,159,290 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	123,061,104 - 123,159,290 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	123,264,801 - 123,365,641 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	123,267,455 - 123,365,641 (+)	Ensembl			mm10	GRCm38
MGSCv37	3	122,970,414 - 123,068,554 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	123,259,518 - 123,357,658 (+)	NCBI		MGSCv36	mm8
Celera	3	129,677,953 - 129,787,733 (+)	NCBI		Celera
Cytogenetic Map	3	G1	NCBI
cM Map	3	53.82	NCBI

Sec24d
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955428	21,381,809 - 21,500,429 (+)	Ensembl
ChiLan1.0	NW_004955428	21,381,809 - 21,475,329 (+)	NCBI	ChiLan1.0	ChiLan1.0

SEC24D
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	116,505,263 - 116,622,112 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	116,802,002 - 116,918,966 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	110,916,508 - 111,033,298 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	121,468,914 - 121,584,647 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	121,468,914 - 121,582,156 (-)	Ensembl			panPan2	panpan1.1

SEC24D
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	37,690,158 - 37,795,762 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	37,690,399 - 37,924,252 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	4,279,402 - 4,383,982 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	37,911,481 - 38,017,151 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	37,911,481 - 38,014,944 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	37,933,932 - 38,039,567 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	37,657,914 - 37,762,852 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	2,038,782 - 2,143,773 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Sec24d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405301	67,620,346 - 67,698,409 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936869	522,706 - 563,704 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936869	485,706 - 566,591 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SEC24D
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	104,882,035 - 105,005,398 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	8	104,560,723 - 105,005,400 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	112,778,267 - 112,789,489 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SEC24D
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	66,208,005 - 66,318,222 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	66,207,765 - 66,318,206 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	45,045,256 - 45,155,626 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sec24d
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624867	5,536,888 - 5,631,867 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Sec24d
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	36,450,702 - 36,550,246 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Sec24d
622 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	506
Count of miRNA genes:	232
Interacting mature miRNAs:	264
Transcripts:	ENSRNOT00000064809
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	163997722	225110681	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	169358774	214358774	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
631563	Hcuc3	Hepatic copper content QTL 3	3.87		liver copper amount (VT:0003065)	liver copper weight to liver dry weight ratio (CMO:0001512)	2	212145502	231732847	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149957381	221199885	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1300126	Bp175	Blood pressure QTL 175	3.46		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	204795005	249795005	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
61458	Bp10	Blood pressure QTL 10	3.42		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	191709311	217961898	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	145807215	220931416	Rat
1302789	Stl26	Serum triglyceride level QTL 26	3.1	0.0035	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	206613059	226891081	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	122597372	215234002	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	196140964	251540988	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	205135267	250135267	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170652929	215652929	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	220931218	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	192287802	229609668	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	188565047	233565047	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	184856304	229856304	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	184856304	229856304	Rat
631203	Gluco14	Glucose level QTL 14		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	2	209350500	221678003	Rat
1298083	Bp158	Blood pressure QTL 158	2.62		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	191709311	217961898	Rat
1357991	Ael2	Aortic elastin QTL 2	4.2	0.000071	aorta elastin amount (VT:0003905)	aortic elastin	2	169227906	214227906	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1331745	Bp203	Blood pressure QTL 203	4.377		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	192287802	221089121	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	192287802	237287802	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	184856304	229856304	Rat
1578671	Bmd10	Bone mineral density QTL 10	5.4		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	175931416	220931416	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	182024327	227024327	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	159440760	228950743	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	184482291	229482291	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	210956252	251712708	Rat
1598813	Memor9	Memory QTL 9	2.7		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	202029709	236904960	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
2298479	Eau5	Experimental allergic uveoretinitis QTL 5		0.0021	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	2	205135267	225627153	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	114384617	215381366	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	186850607	231850607	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	192287802	237287802	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	114384617	215381366	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	223841096	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	182635347	227635347	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	220008837	Rat
1598835	Anxrr18	Anxiety related response QTL 18	2.98		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	2	203664411	248664411	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	184856304	229856304	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166372086	229820014	Rat

Markers in Region

UniSTS:234818

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	211,510,769 - 211,510,858 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	227,545,448 - 227,545,536	NCBI	Rnor6.0
Rnor_5.0	2	246,904,396 - 246,904,484	UniSTS	Rnor5.0
RGSC_v3.4	2	220,081,023 - 220,081,111	UniSTS	RGSC3.4
Celera	2	203,924,201 - 203,924,289	UniSTS
Cytogenetic Map	2	q42	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
17	12	81	201	91	90	59	124	59	6	423	242	15	184	97	114	31	32	32

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001309453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000064809 ⟹ ENSRNOP00000059031

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	214,103,190 - 214,211,144 (+)	Ensembl
mRatBN7.2 Ensembl	2	211,418,623 - 211,526,587 (+)	Ensembl
Rnor_6.0 Ensembl	2	227,455,722 - 227,562,319 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105511 ⟹ ENSRNOP00000094826

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	214,103,509 - 214,211,144 (+)	Ensembl

RefSeq Acc Id:

NM_001309453 ⟹ NP_001296382

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	214,103,200 - 214,211,155 (+)	NCBI
mRatBN7.2	2	211,418,623 - 211,526,588 (+)	NCBI
Rnor_6.0	2	227,455,723 - 227,562,801 (+)	NCBI
Celera	2	203,833,456 - 203,940,242 (+)	NCBI

Sequence:

show sequence

ACTCGCAGCCCAGAGCGACTCGGCGGCGGCGGCGGTGGCGCGGGGCGCGGAGCGTGCAGAGCAG
GATTCTTCTGCAGTAGCTCTCCTTTGGAATGATATTTTCATAATGAGCCAACAAGGTTACGTGG
CGACACCCCCCTATTCTCAGTCCCAGCCTGGAATGGGCATTTCTCCCCCTCACTACGGGCACTA
TGGGGACCCGTCCCATGTGTCCTCTCCACCAGGCATGATGAAGCCTCCGGGGCCTACAGGAGCC
ACTGCTCCTTCAGGGCTGCTGCCCCCAGGTCCTTTACCTCCTGGACCCCCACAGTTTGGTCCCA
ATGGAGCCCATGCCGCAGGCCATCCTCCTCAAAGATTTCCGGGACACCCACCCGTCAATAATGC
AGCACCCCCTTATGCATCAGGCCAGCCCCTGCCACAGTCATCTTACCCAGGTCCTGGGTCCACC
TCCTCTGTCACCCAGCTGGGCAGTCAGTTCGGCTCCATGCAGATCAACAACTATGGTGTGGGCG
TGACTCCCCAGGGCCAGGGTCCGCCTGGCCCCCAGTCAGCAGGCGCCTTTCAGGGGCCTCCACA
GCCTACACAGCCATCTATTCTGCAGCCAGGACCTCAGGTTCCACCACCACCACCCACCGCCATG
AACGGCCCTGGTGCCTCTCCAATGTCTGCACCAGCTCACAGGCAAGATGGACTTCCTGCGCCTA
CTCCTCTGAATGCCCAGTATCAACCTCCACCTCCACCAGGCCAGACCCTGGGTGCTGGTTACCA
TCCACAGCAAGCAGCCAACTATGGACCACAGATGGGAGGTGCACAGCTGTCCTACCCAGGAGGT
TTTCCTGGAGGTCCGGCACAGATGGCTGGGCCAGCACCTCAGCTCCAGAGGAAGCTTGATCCAG
ACTCCATCCCCAGCCCCATTCAAGTGATCGAGAATGACAGGGCCACCAGAGGCGGACAGGTCTA
TACCACCAACACCAGGGGCCAGGTGCCTCCACTGGTCACCACCGAGTGTATGATTCAAGATCAA
GGCCACTCGAGCCCCCGCTACATTCGCTGTACCACATACTGCTTCCCATGCACGTCAGACATGG
CCAAGCAAGCCCAGATCCCACTAGCTGCCGTCATCAAACCCTTTGCTGACATTCCATCAAACGA
GACCCCCTTGTACTTGGTGAACCATGGAGAGAGCGGACCAGTGAGATGCAACAGGTGCAAAGCC
TACATGTGCCCGTTCATGCAGTTCATCGAAGGCGGACGGCGCTATCAGTGCGGATTTTGCAGCT
GCGTGAACGATGTCCCACCGTTCTATTTCCAACATCTGGACCACATTGGGAGAAGACTGGACCA
CTATGAGAAGCCAGAGCTGTCTTTAGGATCCTATGAATATGTTGCTACTTTGGATTACTGCAGA
AAGAATAAACCACCCAACCCACCAGCCTTTATCTTCATGATCGATGTCTCGTACAGTAACATAA
AGAACGGGCTCGTCAAGCTCATCTGTGAGGAACTGAAGACCGTGCTGAAGAGGCTACCCAAGGA
GGAGCATGAGGAGAAATCTGCAATTCGAGTTGGTTTCATCACATACAACAAAGTTCTCCACTTC
TTTAACGTGAAGAGTAATCTGGCCCAACCTCAGATGATGGTGGTGACGGATGTTGGAGAGGTCT
TTGTTCCTTTGTTGGATGGGTTCCTTGTCAACTATGAAGAATCCCAGTCTGTGATCCACAATTT
ATTGGACCAGATTCCTGAGATGTTTGCCGACTCCAATGAAAACGAGACAGTCTTTGCTCCTGTC
ATCCAGGCTGGCATGGAGGCCCTGAAGGCAGCAGAGTGCCCTGGGAAGCTCTTCATCTTCCATT
CGTCCCTGCCTACTGCCGAAGCACCGGGAAAGCTCAAGAACAGAGACGACAAAAAGCTGGTTAA
CACAGACAAGGAGAAGATACTTTTCCAGCCCCAAACAGCTGTCTACGAATCTCTGGCCAAGGAC
TGTGTAGCCAACAGCTGCTCGGTGACTCTGTTCCTCTTTCCCAGTCAGTTTGTGGATGTGGCTT
CCTTGGGTCTGGTTCCTCTGCTCACGGGAGGATCCCTTTACAAATACAATGTTTTTCAGGTACA
CGTGGATAGTCAAAGGTTTTTGAACGACCTCCGGAATGATATTGAGAAGAAAATAGGCTTCGAT
GCTATCATGAGGGTTCGGACCAGCACAGGTTTCAGGGCCACCGATTTCTTCGGTGGGATATTCA
TGAACAACACCACAGATGTGGAAATGGCAGCCATCGACTGTGATAAGGCGGTGACCGTGGAGTT
CAAGCACGATGACAAGCTCAGTGAAGATGTCGGGGCTCTGATCCAGTGTGCCCTGCTCTACACG
ACCATCGGTGGTCAGCGAAGACTCCGGATTCACAATGTCGCCTTAAACTGCAGCACCCAGCTAG
CAGATCTGTACAAGAGCTGTGAAACAGATGCCCTGATCAACTTCTTTGCCAAGTCAGCTTTTAA
AGCCGTTTTGAACCAGCCTTTGAAGACCATCCGGGAAATTCTAGTTAATCAGACTGCCCATATG
TTGGCGTGTTACCGGAAGCACTGTGCGAGCCCTTCTGCAGCAAGCCAGCTTATACTGCCAGATT
CCATGAAAGTTCTGCCCGTGTACATGAACAGTCTGTTGAAAAACTGTGTGCTGCTCAGCAGACC
CGAGATCTCCCCTGACGAGCGGGCGTACCAACGGCAGCTGGTGATGACCATGGGCGTGGCTGAC
TCCCAGCTCTTCTTCTATCCACTGCTCCTGCCAATACACACGTTGGATGTGAAGAGCGCAGCAC
TGCCGCCGGCTGTCCGCTGCTCCGAGTCCCGACTCTCCGAAGAAGGAATATTCCTGCTGGCTGA
TGGTCTGAACATGTTCTTGTGGTTCGGAGTGGGGAGCCCAGCGGAGCTGATTCAGGGAATATTC
AATGTGCCATCGTTTGCACATATCAACACAGATATGACATCGCTGCCTGAGGTGGGAAGTCCGC
ACTCTCAACAACTCAGGATGATTATGAATAATATCCAGCAGAAGAAGCCATACTCAATGAAGCT
CATCATAGTGAAGCAGCGAGAGCAGCGGGAGATGGTTTTCCGACAGTTCCTGGTGGAAGACAAA
GGGCTCTACGGAGGATCATCTTATGTGGATTTCCTCTGCTGTGTGCACAAGGAGATCTGTCAGC
TGCTTAACTGAGTACTCCGCTCTCCCACTGAGGCTGCATCCCTGAGGAGACAGTCTCCGACTTG
GTGCCTAATTTTCTGATGATAGTAGGCTAGTTTTAATTTCTCGATTACTTTCAGGATAGCTTGC
CTGGACAGCACCCAGACCGTCAGCTTTGGTGCTCAGTGGTAGCCCGTGGAGGGGTAGTGTACTG
TAAAGGGAACACTATTTGCTGTCCAACTTCTAATTTCTAAAGCTGACACAATTTGCATTTCATA
AATACATAGTTTACAGAACCATTTGCAGCCTCAATTTTCTTTGTGCTTGATATATAAATTATTT
TTCAAACTGTATAGATTCATGGTAAAATTATCTTGGTTCCTCTCTCTTTTACAATGAGAGGAAA
AGATTTCATTTTTATCTTACACCTAATGTTTTTAAAACCCCGTGACTACATTAAACAGATTTTT
TTTTTCAACTTAAGATCTGCAACAGCAGACTTTTAAAAAAGCCTGAAATCTGTCTGGTAGAACA
ATTTGTGTTCTCCTTTTTTCATAATTATATATTGTCTGTTTAAAATATTTTCCAGTTGTTTTGT
CTATAAAATGGTATCTATATTCTTAATGGTTCTTTGTACAATTTTGATGGTTTCTACCTGTATA
TAATGGATCTTAACCAATATCAATAAATTACTTCATGTACTCTGGCTTAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006233272 ⟹ XP_006233334

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	214,103,138 - 214,211,145 (+)	NCBI
mRatBN7.2	2	211,418,557 - 211,526,588 (+)	NCBI
Rnor_6.0	2	227,455,704 - 227,562,801 (+)	NCBI
Rnor_5.0	2	246,815,650 - 246,919,957 (+)	NCBI

Sequence:

show sequence

GCCGGGCGCCTGACGTGGCACTCGCAGCCCAGAGCGACTCGGCGGCGGCGGCGGTGGCGCGGGG
CGCGGAGCGTGCAGAGCAGGATTCTTCTGCAGTAGCTCTCCTTTGGAATGATATTTTCATAATG
AGCCAACAAGGTTACGTGGCGACACCCCCCTATTCTCAGTCCCAGCCTGGAATGGGCATTTCTC
CCCCTCACTACGGGCACTATGGGGACCCGTCCCATGTGTCCTCTCCACCAGGCATGATGAAGCC
TCCGGGGCCTACAGGAGCCACTGCTCCTTCAGGGCTGCTGCCCCCAGGTCCTTTACCTCCTGGA
CCCCCACAGTTTGGTCCCAATGGAGCCCATGCCGCAGGCCATCCTCCTCAAAGATTTCCGGGAC
ACCCACCCGTCAATAATGCAGCACCCCCTTATGCATCAGGCCAGCCCCTGCCACAGTCATCTTA
CCCAGGTCCTGGGTCCACCTCCTCTGTCACCCAGCTGGGCAGTCAGTTCGGCTCCATGCAGATC
AACAACTATGGTGTGGGCGTGACTCCCCAGGGCCAGGGTCCGCCTGGCCCCCAGTCAGCAGGCG
CCTTTCAGGGGCCTCCACAGCCTACACAGCCATCTATTCTGCAGCCAGGACCTCAGGTTCCACC
ACCACCACCCACCGCCATGAACGGCCCTGGTGCCTCTCCAATGTCTGCACCAGCTCACAGGCAA
GATGGACTTCCTGCGCCTACTCCTCTGAATGCCCAGTATCAACCTCCACCTCCACCAGGCCAGA
CCCTGGGTGCTGGTTACCATCCACAGCAAGCCAACTATGGACCACAGATGGGAGGTGCACAGCT
GTCCTACCCAGGAGGTTTTCCTGGAGGTCCGGCACAGATGGCTGGGCCAGCACCTCAGCTCCAG
AGGAAGCTTGATCCAGACTCCATCCCCAGCCCCATTCAAGTGATCGAGAATGACAGGGCCACCA
GAGGCGGACAGGTCTATACCACCAACACCAGGGGCCAGGTGCCTCCACTGGTCACCACCGAGTG
TATGATTCAAGATCAAGGCCACTCGAGCCCCCGCTACATTCGCTGTACCACATACTGCTTCCCA
TGCACGTCAGACATGGCCAAGCAAGCCCAGATCCCACTAGCTGCCGTCATCAAACCCTTTGCTG
ACATTCCATCAAACGAGACCCCCTTGTACTTGGTGAACCATGGAGAGAGCGGACCAGTGAGATG
CAACAGGTGCAAAGCCTACATGTGCCCGTTCATGCAGTTCATCGAAGGCGGACGGCGCTATCAG
TGCGGATTTTGCAGCTGCGTGAACGATGTCCCACCGTTCTATTTCCAACATCTGGACCACATTG
GGAGAAGACTGGACCACTATGAGAAGCCAGAGCTGTCTTTAGGATCCTATGAATATGTTGCTAC
TTTGGATTACTGCAGAAAGAATAAACCACCCAACCCACCAGCCTTTATCTTCATGATCGATGTC
TCGTACAGTAACATAAAGAACGGGCTCGTCAAGCTCATCTGTGAGGAACTGAAGACCGTGCTGA
AGAGGCTACCCAAGGAGGAGCATGAGGAGAAATCTGCAATTCGAGTTGGTTTCATCACATACAA
CAAAGTTCTCCACTTCTTTAACGTGAAGAGTAATCTGGCCCAACCTCAGATGATGGTGGTGACG
GATGTTGGAGAGGTCTTTGTTCCTTTGTTGGATGGGTTCCTTGTCAACTATGAAGAATCCCAGT
CTGTGATCCACAATTTATTGGACCAGATTCCTGAGATGTTTGCCGACTCCAATGAAAACGAGAC
AGTCTTTGCTCCTGTCATCCAGGCTGGCATGGAGGCCCTGAAGGCAGCAGAGTGCCCTGGGAAG
CTCTTCATCTTCCATTCGTCCCTGCCTACTGCCGAAGCACCGGGAAAGCTCAAGAACAGAGACG
ACAAAAAGCTGGTTAACACAGACAAGGAGAAGATACTTTTCCAGCCCCAAACAGCTGTCTACGA
ATCTCTGGCCAAGGACTGTGTAGCCAACAGCTGCTCGGTGACTCTGTTCCTCTTTCCCAGTCAG
TTTGTGGATGTGGCTTCCTTGGGTCTGGTTCCTCTGCTCACGGGAGGATCCCTTTACAAATACA
ATGTTTTTCAGGTACACGTGGATAGTCAAAGGTTTTTGAACGACCTCCGGAATGATATTGAGAA
GAAAATAGGCTTCGATGCTATCATGAGGGTTCGGACCAGCACAGGTTTCAGGGCCACCGATTTC
TTCGGTGGGATATTCATGAACAACACCACAGATGTGGAAATGGCAGCCATCGACTGTGATAAGG
CGGTGACCGTGGAGTTCAAGCACGATGACAAGCTCAGTGAAGATGTCGGGGCTCTGATCCAGTG
TGCCCTGCTCTACACGACCATCGGTGGTCAGCGAAGACTCCGGATTCACAATGTCGCCTTAAAC
TGCAGCACCCAGCTAGCAGATCTGTACAAGAGCTGTGAAACAGATGCCCTGATCAACTTCTTTG
CCAAGTCAGCTTTTAAAGCCGTTTTGAACCAGCCTTTGAAGACCATCCGGGAAATTCTAGTTAA
TCAGACTGCCCATATGTTGGCGTGTTACCGGAAGCACTGTGCGAGCCCTTCTGCAGCAAGCCAG
CTTATACTGCCAGATTCCATGAAAGTTCTGCCCGTGTACATGAACAGTCTGTTGAAAAACTGTG
TGCTGCTCAGCAGACCCGAGATCTCCCCTGACGAGCGGGCGTACCAACGGCAGCTGGTGATGAC
CATGGGCGTGGCTGACTCCCAGCTCTTCTTCTATCCACTGCTCCTGCCAATACACACGTTGGAT
GTGAAGAGCGCAGCACTGCCGCCGGCTGTCCGCTGCTCCGAGTCCCGACTCTCCGAAGAAGGAA
TATTCCTGCTGGCTGATGGTCTGAACATGTTCTTGTGGTTCGGAGTGGGGAGCCCAGCGGAGCT
GATTCAGGGAATATTCAATGTGCCATCGTTTGCACATATCAACACAGATATGACATCGCTGCCT
GAGGTGGGAAGTCCGCACTCTCAACAACTCAGGATGATTATGAATAATATCCAGCAGAAGAAGC
CATACTCAATGAAGCTCATCATAGTGAAGCAGCGAGAGCAGCGGGAGATGGTTTTCCGACAGTT
CCTGGTGGAAGACAAAGGGCTCTACGGAGGATCATCTTATGTGGATTTCCTCTGCTGTGTGCAC
AAGGAGATCTGTCAGCTGCTTAACTGAGTACTCCGCTCTCCCACTGAGGCTGCATCCCTGAGGA
GACAGTCTCCGACTTGGTGCCTAATTTTCTGATGATAGTAGGCTAGTTTTAATTTCTCGATTAC
TTTCAGGATAGCTTGCCTGGACAGCACCCAGACCGTCAGCTTTGGTGCTCAGTGGTAGCCCGTG
GAGGGGTAGTGTACTGTAAAGGGAACACTATTTGCTGTCCAACTTCTAATTTCTAAAGCTGACA
CAATTTGCATTTCATAAATACATAGTTTACAGAACCATTTGCAGCCTCAATTTTCTTTGTGCTT
GATATATAAATTATTTTTCAAACTGTATAGATTCATGGTAAAATTATCTTGGTTCCTCTCTCTT
TTACAATGAGAGGAAAAGATTTCATTTTTATCTTACACCTAATGTTTTTAAAACCCCGTGACTA
CATTAAACAGATTTTTTTTTTCAACTTAAGATCTGCAACAGCAGACTTTTAAAAAAGCCTGAAA
TCTGTCTGGTAGAACAATTTGTGTTCTCCTTTTTTCATAATTATATATTGTCTGTTTAAAATAT
TTTCCAGTTGTTTTGTCTATAAAATGGTATCTATATTCTTAATGGTTCTTTGTACAATTTTGAT
GGTTTCTACCTGTATATAATGGATCTTAACCAATATCAATAAATTACTTCATGTACTCTGGCTT
A

hide sequence

Protein Sequences


Protein RefSeqs	NP_001296382	(Get FASTA)	NCBI Sequence Viewer
	XP_006233334	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68946	(Get FASTA)	NCBI Sequence Viewer
	EDL82122	(Get FASTA)	NCBI Sequence Viewer
	EDL82123	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000059031
	ENSRNOP00000059031.5
	ENSRNOP00000094826.2

RefSeq Acc Id:	XP_006233334 ⟸ XM_006233272
- Peptide Label:	isoform X1
- UniProtKB:	G3V9S9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSQQGYVATPPYSQSQPGMGISPPHYGHYGDPSHVSSPPGMMKPPGPTGATAPSGLLPPGPLPP GPPQFGPNGAHAAGHPPQRFPGHPPVNNAAPPYASGQPLPQSSYPGPGSTSSVTQLGSQFGSMQ INNYGVGVTPQGQGPPGPQSAGAFQGPPQPTQPSILQPGPQVPPPPPTAMNGPGASPMSAPAHR QDGLPAPTPLNAQYQPPPPPGQTLGAGYHPQQANYGPQMGGAQLSYPGGFPGGPAQMAGPAPQL QRKLDPDSIPSPIQVIENDRATRGGQVYTTNTRGQVPPLVTTECMIQDQGHSSPRYIRCTTYCF PCTSDMAKQAQIPLAAVIKPFADIPSNETPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRY QCGFCSCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKNKPPNPPAFIFMID VSYSNIKNGLVKLICEELKTVLKRLPKEEHEEKSAIRVGFITYNKVLHFFNVKSNLAQPQMMVV TDVGEVFVPLLDGFLVNYEESQSVIHNLLDQIPEMFADSNENETVFAPVIQAGMEALKAAECPG KLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTAVYESLAKDCVANSCSVTLFLFPS QFVDVASLGLVPLLTGGSLYKYNVFQVHVDSQRFLNDLRNDIEKKIGFDAIMRVRTSTGFRATD FFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDVGALIQCALLYTTIGGQRRLRIHNVAL NCSTQLADLYKSCETDALINFFAKSAFKAVLNQPLKTIREILVNQTAHMLACYRKHCASPSAAS QLILPDSMKVLPVYMNSLLKNCVLLSRPEISPDERAYQRQLVMTMGVADSQLFFYPLLLPIHTL DVKSAALPPAVRCSESRLSEEGIFLLADGLNMFLWFGVGSPAELIQGIFNVPSFAHINTDMTSL PEVGSPHSQQLRMIMNNIQQKKPYSMKLIIVKQREQREMVFRQFLVEDKGLYGGSSYVDFLCCV HKEICQLLN hide sequence

RefSeq Acc Id:

NP_001296382 ⟸ NM_001309453

- UniProtKB:

B5DF68 (UniProtKB/TrEMBL), G3V9S9 (UniProtKB/TrEMBL), A6HVI6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSQQGYVATPPYSQSQPGMGISPPHYGHYGDPSHVSSPPGMMKPPGPTGATAPSGLLPPGPLPP
GPPQFGPNGAHAAGHPPQRFPGHPPVNNAAPPYASGQPLPQSSYPGPGSTSSVTQLGSQFGSMQ
INNYGVGVTPQGQGPPGPQSAGAFQGPPQPTQPSILQPGPQVPPPPPTAMNGPGASPMSAPAHR
QDGLPAPTPLNAQYQPPPPPGQTLGAGYHPQQAANYGPQMGGAQLSYPGGFPGGPAQMAGPAPQ
LQRKLDPDSIPSPIQVIENDRATRGGQVYTTNTRGQVPPLVTTECMIQDQGHSSPRYIRCTTYC
FPCTSDMAKQAQIPLAAVIKPFADIPSNETPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRR
YQCGFCSCVNDVPPFYFQHLDHIGRRLDHYEKPELSLGSYEYVATLDYCRKNKPPNPPAFIFMI
DVSYSNIKNGLVKLICEELKTVLKRLPKEEHEEKSAIRVGFITYNKVLHFFNVKSNLAQPQMMV
VTDVGEVFVPLLDGFLVNYEESQSVIHNLLDQIPEMFADSNENETVFAPVIQAGMEALKAAECP
GKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTAVYESLAKDCVANSCSVTLFLFP
SQFVDVASLGLVPLLTGGSLYKYNVFQVHVDSQRFLNDLRNDIEKKIGFDAIMRVRTSTGFRAT
DFFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDVGALIQCALLYTTIGGQRRLRIHNVA
LNCSTQLADLYKSCETDALINFFAKSAFKAVLNQPLKTIREILVNQTAHMLACYRKHCASPSAA
SQLILPDSMKVLPVYMNSLLKNCVLLSRPEISPDERAYQRQLVMTMGVADSQLFFYPLLLPIHT
LDVKSAALPPAVRCSESRLSEEGIFLLADGLNMFLWFGVGSPAELIQGIFNVPSFAHINTDMTS
LPEVGSPHSQQLRMIMNNIQQKKPYSMKLIIVKQREQREMVFRQFLVEDKGLYGGSSYVDFLCC
VHKEICQLLN

hide sequence

Ensembl Acc Id:

ENSRNOP00000059031 ⟸ ENSRNOT00000064809

Ensembl Acc Id:

ENSRNOP00000094826 ⟸ ENSRNOT00000105511

Protein Domains

Gelsolin-like Sec23/Sec24 beta-sandwich Sec23/Sec24 helical Sec23/Sec24 trunk Zinc finger Sec23/Sec24-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V9S9-F1-model_v2	AlphaFold	G3V9S9	1-1033	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691737

Promoter ID:

EPDNEW_R2258

Type:

initiation region

Name:

Sec24d_1

Description:

SEC24 homolog D, COPII coat complex component

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	227,455,723 - 227,455,783	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311720	AgrOrtholog
BioCyc Gene	G2FUF-51328	BioCyc
Ensembl Genes	ENSRNOG00000014872	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000064809	ENTREZGENE
	ENSRNOT00000064809.5	UniProtKB/TrEMBL
	ENSRNOT00000105511.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.20.10	UniProtKB/TrEMBL
	3.40.50.410	UniProtKB/TrEMBL
	beta-sandwich domain of Sec23/24	UniProtKB/TrEMBL
	Sec23/Sec24 helical domain	UniProtKB/TrEMBL
	Zn-finger domain of Sec23/24	UniProtKB/TrEMBL
InterPro	ADF-H/Gelsolin-like_dom	UniProtKB/TrEMBL
	Gelsolin-like_dom_sf	UniProtKB/TrEMBL
	Gelsolin_dom	UniProtKB/TrEMBL
	Sec23/24_helical_dom	UniProtKB/TrEMBL
	Sec23/24_helical_dom_sf	UniProtKB/TrEMBL
	Sec23/24_trunk_dom	UniProtKB/TrEMBL
	Sec23_24_beta_S	UniProtKB/TrEMBL
	SEC23_SEC24_subfamily	UniProtKB/TrEMBL
	Sec24-like_trunk_dom	UniProtKB/TrEMBL
	vWFA_dom_sf	UniProtKB/TrEMBL
	Znf_Sec23_Sec24	UniProtKB/TrEMBL
	Znf_Sec23_Sec24_sf	UniProtKB/TrEMBL
KEGG Report	rno:310843	UniProtKB/TrEMBL
NCBI Gene	310843	ENTREZGENE
PANTHER	PROTEIN TRANSPORT PROTEIN SEC24D	UniProtKB/TrEMBL
	SEC24-RELATED PROTEIN	UniProtKB/TrEMBL
Pfam	Gelsolin	UniProtKB/TrEMBL
	Sec23_BS	UniProtKB/TrEMBL
	Sec23_helical	UniProtKB/TrEMBL
	Sec23_trunk	UniProtKB/TrEMBL
	zf-Sec23_Sec24	UniProtKB/TrEMBL
PhenoGen	Sec24d	PhenoGen
RatGTEx	ENSRNOG00000014872	RatGTEx
Superfamily-SCOP	beta-sandwich domain of Sec23/24	UniProtKB/TrEMBL
	Sec23_helical	UniProtKB/TrEMBL
	SSF53300	UniProtKB/TrEMBL
	SSF82754	UniProtKB/TrEMBL
	SSF82919	UniProtKB/TrEMBL
UniProt	A0A0G2QC63_RAT	UniProtKB/TrEMBL
	A0A8I6AII2_RAT	UniProtKB/TrEMBL
	A6HVI6	ENTREZGENE, UniProtKB/TrEMBL
	B5DF68	ENTREZGENE
	G3V9S9	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	B5DF68	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-13	Sec24d	SEC24 homolog D, COPII coat complex component	Sec24d	SEC24 family member D	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-11-11	Sec24d	SEC24 family member D	Sec24d	SEC24 family, member D (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-20	Sec24d	SEC24 family, member D (S. cerevisiae)	Sec24d	SEC24 related gene family, member D (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Sec24d	SEC24 related gene family, member D (S. cerevisiae)	Sec24d_predicted	SEC24 related gene family, member D (S. cerevisiae) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Sec24d_predicted	SEC24 related gene family, member D (S. cerevisiae) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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