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Gene: Mill1 (MHC I like leukocyte 1) Rattus norvegicus

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Symbol:

Mill1

Name:

MHC I like leukocyte 1

RGD ID:

1311714

Description:

Predicted to enable natural killer cell lectin-like receptor binding activity and receptor ligand activity. Predicted to be involved in several processes, including defense response to other organism; negative regulation of natural killer cell activation; and negative regulation of natural killer cell mediated cytotoxicity. Predicted to be located in cell surface. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human MICA (MHC class I polypeptide-related sequence A); INTERACTS WITH (+)-catechin (ortholog); 2-hydroxypropanoic acid (ortholog); 5-aza-2'-deoxycytidine (ortholog).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC292671; MHC class I-like located near the leukocyte receptor complex 1; MHC class I-like located near the LRC, 1; MHC class I-like protein MILL1; mhc i - like leukocyte 1

RGD Orthologs

Human

Dog

Pig

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	87,500,591 - 87,526,983 (+)	NCBI		GRCr8
mRatBN7.2	1	78,372,798 - 78,398,932 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	78,372,802 - 78,398,930 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	83,761,826 - 83,787,919 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	92,318,175 - 92,344,204 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	85,516,941 - 85,543,040 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	79,631,266 - 79,657,943 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	79,631,668 - 79,657,941 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	80,887,094 - 80,914,226 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	78,075,659 - 78,102,700 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	78,153,769 - 78,174,435 (+)	NCBI
Celera	1	72,840,406 - 72,866,591 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

coronary aneurysm (ISO)

hepatocellular carcinoma (ISO)

megacolon (ISO)

oral submucous fibrosis (ISO)

proteasome-associated autoinflammatory syndrome 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

2-hydroxypropanoic acid (ISO)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (ISO)

butanal (ISO)

caffeine (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

doxorubicin (ISO)

entinostat (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

gefitinib (ISO)

ketoconazole (ISO)

lycopene (ISO)

malathion (ISO)

methyl methanesulfonate (ISO)

paracetamol (ISO)

phenobarbital (ISO)

propanal (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sulfasalazine (ISO)

temozolomide (ISO)

thimerosal (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vorinostat (ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

defense response to bacterium (ISO)

defense response to virus (ISO)

DNA damage response (ISO)

gamma-delta T cell activation (ISO)

immune response (IBA)

immune response to tumor cell (ISO)

natural killer cell mediated cytotoxicity (ISO)

negative regulation of natural killer cell activation (ISO)

negative regulation of natural killer cell mediated cytotoxicity (ISO)

response to heat (ISO)

signal transduction (IEA)

T cell mediated cytotoxicity (ISO)

Cellular Component

cell surface (ISO)

external side of plasma membrane (IBA)

extracellular space (IBA,ISO)

membrane (IEA)

plasma membrane (IEA,ISO)

side of membrane (IEA)

Molecular Function

beta-2-microglobulin binding (ISO)

natural killer cell lectin-like receptor binding (ISO)

protein binding (ISO)

receptor ligand activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8901601	PMID:9497295	PMID:10359807	PMID:10426993	PMID:11224526	PMID:11239445	PMID:11287116	PMID:11485740	PMID:11491531	PMID:11830641	PMID:12569559	PMID:12782710
PMID:15162429	PMID:15995699	PMID:16750166	PMID:16920948	PMID:18676862	PMID:20068167

Genomics

Comparative Map Data

Mill1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	87,500,591 - 87,526,983 (+)	NCBI		GRCr8
mRatBN7.2	1	78,372,798 - 78,398,932 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	78,372,802 - 78,398,930 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	83,761,826 - 83,787,919 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	92,318,175 - 92,344,204 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	85,516,941 - 85,543,040 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	79,631,266 - 79,657,943 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	79,631,668 - 79,657,941 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	80,887,094 - 80,914,226 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	78,075,659 - 78,102,700 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	78,153,769 - 78,174,435 (+)	NCBI
Celera	1	72,840,406 - 72,866,591 (+)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

MICA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	31,400,711 - 31,415,315 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	31,399,784 - 31,415,315 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	31,368,488 - 31,383,092 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	31,479,350 - 31,491,069 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	31,479,349 - 31,491,069	NCBI
Celera	6	32,969,923 - 33,031,516 (+)	NCBI		Celera
Cytogenetic Map	6	p21.33	NCBI
HuRef	6	31,157,962 - 31,173,490 (+)	NCBI		HuRef
CHM1_1	6	31,369,533 - 31,385,168 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	31,256,597 - 31,271,201 (+)	NCBI		T2T-CHM13v2.0

MICA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ROS_Cfam_1.0	12	1,107,161 - 1,110,593 (+)	NCBI		ROS_Cfam_1.0
UNSW_CanFamBas_1.0	12	1,034,631 - 1,038,065 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	1,101,167 - 1,104,600 (+)	NCBI		UU_Cfam_GSD_1.0

LOC100153163
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	7	23,596,900 - 23,610,431 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	27,222,832 - 27,236,381 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Variants

Variants in Mill1
284 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	144
Count of miRNA genes:	119
Interacting mature miRNAs:	125
Transcripts:	ENSRNOT00000035286
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	35239598	78430678	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49393172	94393172	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	53895117	82174945	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	33449848	78449848	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	49361465	82174945	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	11481312	82174945	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	34836858	79836858	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	50343510	99980958	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	35239598	78430678	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	11481312	82174945	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
2302059	Pia36	Pristane induced arthritis QTL 36	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	43333002	88333002	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	11481312	82174945	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	72197680	90508767	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	11481312	82174945	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	45803140	78430678	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	77876254	106047988	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	28879780	78430678	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	32737273	90665040	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	53863041	90532583	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	33449848	78449848	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	53895117	82174945	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	34836858	79836858	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat

Markers in Region

PMC129743P2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	78,390,475 - 78,391,265 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	79,649,489 - 79,650,278	NCBI	Rnor6.0
Rnor_5.0	1	80,905,772 - 80,906,561	UniSTS	Rnor5.0
RGSC_v3.4	1	78,093,744 - 78,094,533	UniSTS	RGSC3.4
Celera	1	72,858,137 - 72,858,926	UniSTS
Cytogenetic Map	1	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	29	98	55	54	23	25	23	6	159	77	78	42	59	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001011931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008758906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008758907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB113960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB113999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB126063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC093995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000035286 ⟹ ENSRNOP00000033032

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	78,372,802 - 78,398,930 (+)	Ensembl
Rnor_6.0 Ensembl	1	79,631,812 - 79,657,941 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083546 ⟹ ENSRNOP00000071141

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	78,372,802 - 78,393,012 (+)	Ensembl
Rnor_6.0 Ensembl	1	79,631,668 - 79,652,788 (+)	Ensembl

RefSeq Acc Id:

NM_001011931 ⟹ NP_001011931

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	87,500,850 - 87,526,983 (+)	NCBI
mRatBN7.2	1	78,372,798 - 78,398,932 (+)	NCBI
Rnor_6.0	1	79,631,821 - 79,657,943 (+)	NCBI
Rnor_5.0	1	80,887,094 - 80,914,226 (+)	NCBI
RGSC_v3.4	1	78,075,659 - 78,102,700 (+)	RGD
Celera	1	72,840,406 - 72,866,591 (+)	RGD

Sequence:

show sequence

TCAGGAGTCTCAGAAAGGCAGAAGAAGATGATGTTGTCCAGGGACCTCAGAGCTGAAGCTGCAG
TTCGGCTGTGGATAATGTTCTTGCTCCTGGAGGATTTACTGGGCGCTTGTGCAGTGGGTGACTA
CCAAAGACGAGTGCCTTCTGCCCCCAACACAGACATCAGGAACACTCTAGAGAAGCCTAGAGTA
ACCACACAGGAGGTAGCAGGACCCCACACTCTGCGCTATGACCTCATGGCCTTGTCTCTGAAGT
TGCCTGAGTTGCCCCAGGTCCTGATCTGGAGATACTTTGATGATGAGCCCTTCCTACATTATAA
TGAAAGCAGCAACAGAACAGACTCCTGGGAACCTAGGATCAAGAGACATTGGAGAGCTATGACT
TGGGCAAGAGAGACTGAGGATCTGCAGGAAATGGTGGAGCAACTCAAAAGGATGCTAGCTGAGG
TCACAGGCCAGAAAGGCCAAGATAAGGGCCTTCACATCCTCCAGGCAACCCTGGGCTGTGAGCT
TCAAAGAAATGGAAGCACTAGAGGCTTCTGGCACCTGGGCTATGACGGGCGGAACCTCCTCACC
TTCGACCAGAAGACTCTCACATGGACAATGGATATGCCCTTCACCCAGCAGAAGAAGACGTTCT
GGGAGCCACGTGCACCCAGGGCTGACCTAGTTAAGACGTTCTTGGATGACACATGTCCTGCTCA
GCTCCAGAGACATCTGGCTTCCTTGAGAAGTGAACCACTTGACACAGGTTCCCCGATGGTGATC
GTGACCTTCAGGAATTATCCACTGGGCAGGGTCACACTGACATGCCGGGCTTTTAATCTGTATC
CCCATATGGCCACCAGGGGCACCCTGGCCTGGCTTCAGGATAGGAAGCTGGTAAAGCAGAAAGC
TTTTGAGCCAGGGACCATCTTGCCCAGTGGGGACAGGACCTACCAGATCTGGGTGTCCATTTGG
GTTCTTCCTGGACAGGAACCACAGTTCACCTGTAATCTGAGTTACCATGGTGGCAACATAGAGA
AGCGTGCTGTTATTGTGAACACTGTCTCTGGTGAGAAAACAAGACAACCTTCCACCTCAGGTGT
GGGAGGCAGGGTCAAGAAAAGCCTGTGGACTACAATGACCACAGCTTTTATGGTGACCTCCTGG
ACCAGGAAAACTGGTGGGGACTCCACTCTGCTTCTGCTCTGGTGGCTTCTGTTCTTTTCTACAG
TGTTGGCAGTTCTGACCCTCGTCTAGAGCAGCACGAACACCCAAGACAGCAAGAAACCAGGTTA
CCGAACTCAATGGGCAAGGACTCCGGCACTTCCTGCATTCATTATGGCTCCTGTGCTCTGTATG
GCTCCTGTACTCCATATGATTCCGAACAACAGATTCACAACAGATTCACATCAGGCTCCTTCCA
GAAAAAGGAAGGTTCTCGGGTCTTGTTTTAACTAGCATGTTTGTAGTATCACTGTTATTAGTAC
CTAAAGCTGCTTCCATAGCGACCCAACAAGTACAAACTGCCCATTTTGTTAATTGGCAGATGCC
ATGCAGGAGTAGCAGCAATGGTCAAGTGAGCTCCCTGGAGAAGGCCCACCATCTTGTCCTCCTG
AGATGCGTGTGCTCTGGTGAGGCATTGCCCCAGAGACTTAGTCCCAGGGCTGTTCCTGCTACTG
TGTGTTTTCTCATGGTTGTCAGTACCGTGCTCCTCATTGATTTGGCTTGGTGAGAGTGGACTCC
GGGAGACCCTCACTCACTGCCTACAGACTGTTGTGGTTACTTCCTGGTTGCCAGCCACCCTATT
GGGAAAATGTCCTGCAGATCAACATGAAGATGAGCTTTCGTGAATTAATGCCATTTAGGTGGTT
GTTTTGCCAGAAAGATGTAGTAAAGTTAGAACTGAGAATAAATTGTGCCCCCTCCTCGTAGAAT
GGTTAAGTAAGGGCTGCATAACAAGGAGTACAATGAGCTTTCATACATTGCACTAAGAAGAGAA
ATAGGATTAAGACAGATTTGTGATGAAAGAAGAAACCTTCTTTCTAGGTCCGGTCCAAGGAAGA
AGCCACAGGTGTGCACTGTGATAAAGCAAGGCCGTGTGGAACTGTTGCTTTGAACTTATAACGA
GCTTACAAAATGAAAAGCTGCTTTGAACTTACTATCCCTTTGGACAACATCCTTTTGAACTCCC
CTTATATGTAACATTTTCTCTATGAGGTAATTTTATAAATAATTTTTTAATCTAAAAATGTATA
AAAAGGCTAAGAAAAAAGTGTGGCTGTTGAGGCTCTGCCCCATCCAACAAGTGTGTGTGTGTGT
GTGTGTGTGTGTGTGTGTGTATTCTTTATTTCCTTCGTCTGTGAAATTGCCATCAGCTTTTGGC
GCCAGAACAGCAAGAGAGTTAAAAGCCAGAAGTCATTGGCCTTCAGCCTTTGGTTGTGTCCCAC
CTCAGTACCTGATCCAGTTGAAGCTGGCCCACAGCAGCTAATCAGCTAGCTTATAATCCTTCTG
TAGCTTCTGCCTCACAGGAATGTATAGATACAAACCTAGAAGCTGTCTTGAATGCTTTAGAAAC
TATGTGATTGTACCTAGGAGATACAGTACAAACTGCACAGCATCCGTTAGTTACAGGATCCTGC
TGCTGTTATATGTGTATGTTACTCTTTTAAGCTAAATGAAAATGAAATAAAATTTAAAATAACT
TACAGGGAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063283111 ⟹ XP_063139181

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	87,500,591 - 87,526,983 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001011931	(Get FASTA)	NCBI Sequence Viewer
	XP_063139181	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAD54760	(Get FASTA)	NCBI Sequence Viewer
	BAD54762	(Get FASTA)	NCBI Sequence Viewer
	BAD54763	(Get FASTA)	NCBI Sequence Viewer
	BAD54764	(Get FASTA)	NCBI Sequence Viewer
	BAD54765	(Get FASTA)	NCBI Sequence Viewer
	BAD54766	(Get FASTA)	NCBI Sequence Viewer
	BAD54767	(Get FASTA)	NCBI Sequence Viewer
	BAD54768	(Get FASTA)	NCBI Sequence Viewer
	BAD54769	(Get FASTA)	NCBI Sequence Viewer
	BAD54770	(Get FASTA)	NCBI Sequence Viewer
	BAD54771	(Get FASTA)	NCBI Sequence Viewer
	BAD54772	(Get FASTA)	NCBI Sequence Viewer
	BAD54773	(Get FASTA)	NCBI Sequence Viewer
	BAD54774	(Get FASTA)	NCBI Sequence Viewer
	BAD54775	(Get FASTA)	NCBI Sequence Viewer
	BAD54776	(Get FASTA)	NCBI Sequence Viewer
	BAD54777	(Get FASTA)	NCBI Sequence Viewer
	BAD54778	(Get FASTA)	NCBI Sequence Viewer
	BAD54779	(Get FASTA)	NCBI Sequence Viewer
	BAD54780	(Get FASTA)	NCBI Sequence Viewer
	BAD54781	(Get FASTA)	NCBI Sequence Viewer
	BAD54782	(Get FASTA)	NCBI Sequence Viewer
	BAD54783	(Get FASTA)	NCBI Sequence Viewer
	BAD54784	(Get FASTA)	NCBI Sequence Viewer
	BAD54785	(Get FASTA)	NCBI Sequence Viewer
	BAD54786	(Get FASTA)	NCBI Sequence Viewer
	BAD54787	(Get FASTA)	NCBI Sequence Viewer
	BAD54788	(Get FASTA)	NCBI Sequence Viewer
	BAD54789	(Get FASTA)	NCBI Sequence Viewer
	BAD54790	(Get FASTA)	NCBI Sequence Viewer
	BAD54791	(Get FASTA)	NCBI Sequence Viewer
	BAD54792	(Get FASTA)	NCBI Sequence Viewer
	BAD54793	(Get FASTA)	NCBI Sequence Viewer
	BAD54794	(Get FASTA)	NCBI Sequence Viewer
	BAD54795	(Get FASTA)	NCBI Sequence Viewer
	BAD54796	(Get FASTA)	NCBI Sequence Viewer
	BAD54797	(Get FASTA)	NCBI Sequence Viewer
	BAD54798	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000033032
	ENSRNOP00000033032.3
	ENSRNOP00000071141.2
GenBank Protein	Q60I18	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001011931 ⟸ NM_001011931
- Peptide Label:	precursor
- UniProtKB:	Q60I18 (UniProtKB/TrEMBL), Q60I20 (UniProtKB/TrEMBL)
- Sequence:	show sequence MMLSRDLRAEAAVRLWIMFLLLEDLLGACAVGDYQRRVPSAPNTDIRNTLEKPRVTTQEVAGPH TLRYDLMALSLKLPELPQVLIWRYFDDEPFLHYNESSNRTDSWEPRIKRHWRAMTWARETEDLQ EMVEQLKRMLAEVTGQKGQDKGLHILQATLGCELQRNGSTRGFWHLGYDGRNLLTFDQKTLTWT MDMPFTQQKKTFWEPRAPRADLVKTFLDDTCPAQLQRHLASLRSEPLDTGSPMVIVTFRNYPLG RVTLTCRAFNLYPHMATRGTLAWLQDRKLVKQKAFEPGTILPSGDRTYQIWVSIWVLPGQEPQF TCNLSYHGGNIEKRAVIVNTVSGEKTRQPSTSGVGGRVKKSLWTTMTTAFMVTSWTRKTGGDST LLLLWWLLFFSTVLAVLTLV hide sequence

Ensembl Acc Id:

ENSRNOP00000071141 ⟸ ENSRNOT00000083546

Ensembl Acc Id:

ENSRNOP00000033032 ⟸ ENSRNOT00000035286

RefSeq Acc Id:	XP_063139181 ⟸ XM_063283111
- Peptide Label:	isoform X1
- UniProtKB:	Q60I18 (UniProtKB/Swiss-Prot), Q60I20 (UniProtKB/TrEMBL)

Protein Domains

Ig-like Ig-like C1-type Immunoglobulin C1-set MHC class I-like antigen recognition-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q60I18-F1-model_v2	AlphaFold	Q60I18	1-404	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311714	AgrOrtholog
BioCyc Gene	G2FUF-60565	BioCyc
Ensembl Genes	ENSRNOG00000017699	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000035286	ENTREZGENE
	ENSRNOT00000035286.6	UniProtKB/Swiss-Prot
	ENSRNOT00000083546.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.30.500.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Ig-like	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_C1-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_class-I_related	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_I-like_Ag-recog	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_I-like_Ag-recog_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_I/II-like_Ag-recog	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC_I_a_a1/a2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:292671	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	292671	ENTREZGENE
PANTHER	MHC CLASS I-LIKE PROTEIN MILL1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MHC CLASS I-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	C1-set	UniProtKB/TrEMBL
	MHC_I	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mill1	PhenoGen
PRINTS	MHCCLASSI	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017699	RatGTEx
SMART	IGc1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	MHC_I/II-like_Ag-recog	UniProtKB/TrEMBL
	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF54452	UniProtKB/Swiss-Prot
UniProt	A0A8L2R3K0_RAT	UniProtKB/TrEMBL
	MILL1_RAT	UniProtKB/Swiss-Prot
	Q60HY2_RAT	UniProtKB/TrEMBL
	Q60HY3_RAT	UniProtKB/TrEMBL
	Q60HY4_RAT	UniProtKB/TrEMBL
	Q60HY5_RAT	UniProtKB/TrEMBL
	Q60HY6_RAT	UniProtKB/TrEMBL
	Q60HY7_RAT	UniProtKB/TrEMBL
	Q60HY8_RAT	UniProtKB/TrEMBL
	Q60HY9_RAT	UniProtKB/TrEMBL
	Q60HZ0_RAT	UniProtKB/TrEMBL
	Q60HZ1_RAT	UniProtKB/TrEMBL
	Q60HZ2_RAT	UniProtKB/TrEMBL
	Q60HZ3_RAT	UniProtKB/TrEMBL
	Q60HZ4_RAT	UniProtKB/TrEMBL
	Q60HZ5_RAT	UniProtKB/TrEMBL
	Q60HZ6_RAT	UniProtKB/TrEMBL
	Q60HZ7_RAT	UniProtKB/TrEMBL
	Q60HZ8_RAT	UniProtKB/TrEMBL
	Q60HZ9_RAT	UniProtKB/TrEMBL
	Q60I00_RAT	UniProtKB/TrEMBL
	Q60I01_RAT	UniProtKB/TrEMBL
	Q60I02_RAT	UniProtKB/TrEMBL
	Q60I03_RAT	UniProtKB/TrEMBL
	Q60I04_RAT	UniProtKB/TrEMBL
	Q60I05_RAT	UniProtKB/TrEMBL
	Q60I06_RAT	UniProtKB/TrEMBL
	Q60I07_RAT	UniProtKB/TrEMBL
	Q60I08_RAT	UniProtKB/TrEMBL
	Q60I09_RAT	UniProtKB/TrEMBL
	Q60I10_RAT	UniProtKB/TrEMBL
	Q60I11_RAT	UniProtKB/TrEMBL
	Q60I12_RAT	UniProtKB/TrEMBL
	Q60I13_RAT	UniProtKB/TrEMBL
	Q60I14_RAT	UniProtKB/TrEMBL
	Q60I15_RAT	UniProtKB/TrEMBL
	Q60I16_RAT	UniProtKB/TrEMBL
	Q60I17_RAT	UniProtKB/TrEMBL
	Q60I18	ENTREZGENE
	Q60I20	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Mill1	MHC I like leukocyte 1	Mill1_predicted	MHC I like leukocyte 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Mill1_predicted	MHC I - like leukocyte 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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