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Gene: Rae1 (ribonucleic acid export 1) Rattus norvegicus

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Symbol:

Rae1

Name:

ribonucleic acid export 1

RGD ID:

1311540

Description:

Predicted to enable RNA binding activity and ubiquitin binding activity. Predicted to be involved in RNA export from nucleus; regulation of mitotic spindle organization; and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Located in nuclear envelope. Orthologous to human RAE1 (ribonucleic acid export 1); PARTICIPATES IN influenza A pathway; RNA transport pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC362281; MGC124870; MGC125198; mRNA export factor; mRNA-associated protein mrnp 41; rae1 protein homolog; RAE1 RNA export 1 homolog; RAE1 RNA export 1 homolog (S. pombe)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RAE1 (ribonucleic acid export 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rae1 (ribonucleic acid export 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rae1 (ribonucleic acid export 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RAE1 (ribonucleic acid export 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RAE1 (ribonucleic acid export 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rae1 (ribonucleic acid export 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RAE1 (ribonucleic acid export 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RAE1 (ribonucleic acid export 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rae1 (ribonucleic acid export 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RAE1 (ribonucleic acid export 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rae1 (ribonucleic acid export 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rae1 (ribonucleic acid export 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12782	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	GLE2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rae-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Rae1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rae1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	182,197,432 - 182,212,381 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	182,197,459 - 182,213,135 (+)	Ensembl				GRCr8
mRatBN7.2	3	161,779,096 - 161,794,048 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	161,779,088 - 161,794,038 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	165,591,130 - 165,605,882 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	174,090,072 - 174,104,824 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	171,831,889 - 171,846,641 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	171,012,984 - 171,030,392 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	171,015,617 - 171,030,384 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	177,081,924 - 177,096,857 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	163,863,196 - 163,877,975 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	160,972,801 - 160,987,580 (+)	NCBI		Celera
RGSC_v3.1	3	163,769,222 - 163,784,038 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-methylcholine (ISO)

3,4-methylenedioxymethamphetamine (EXP)

4-amino-2,6-dinitrotoluene (EXP)

6-propyl-2-thiouracil (EXP)

amitrole (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

bisphenol A (EXP,ISO)

CGP 52608 (ISO)

chlorpyrifos (EXP,ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

deoxynivalenol (ISO)

dibutyl phthalate (EXP)

dioxygen (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

fenvalerate (EXP)

flutamide (EXP)

folic acid (ISO)

ivermectin (ISO)

methimazole (EXP)

methotrexate (ISO)

methyl methanesulfonate (ISO)

nitrates (ISO)

Nivalenol (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sulforaphane (ISO)

tetrachloromethane (EXP,ISO)

thiram (ISO)

titanium dioxide (ISO)

tremolite asbestos (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

regulation of mitotic spindle organization (IEA,ISO,ISS)

RNA export from nucleus (IBA)

transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery (IBA)

Cellular Component

cytoplasm (IEA)

cytoskeleton (IEA)

fibrillar center (IEA,ISO)

mitotic spindle pole (IEA,ISO,ISS)

nuclear envelope (IDA,IEA,ISO)

nuclear pore (IBA,IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA)

spindle pole (IEA)

Molecular Function

protein binding (IPI,ISO)

RNA binding (IBA,IEA,ISO)

ubiquitin binding (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

influenza A pathway (IEA)

RNA transport pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	RAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegans.	Grill B, etal., J Neurosci. 2012 Feb 22;32(8):2628-36. doi: 10.1523/JNEUROSCI.2901-11.2012.
4.	mRNA binding protein mrnp 41 localizes to both nucleus and cytoplasm.	Kraemer D and Blobel G, Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9119-24.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11567106	PMID:12477932	PMID:15489334	PMID:17172455	PMID:25931508

Genomics

Comparative Map Data

Rae1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	182,197,432 - 182,212,381 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	182,197,459 - 182,213,135 (+)	Ensembl				GRCr8
mRatBN7.2	3	161,779,096 - 161,794,048 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	161,779,088 - 161,794,038 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	165,591,130 - 165,605,882 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	174,090,072 - 174,104,824 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	171,831,889 - 171,846,641 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	171,012,984 - 171,030,392 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	171,015,617 - 171,030,384 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	177,081,924 - 177,096,857 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	163,863,196 - 163,877,975 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	160,972,801 - 160,987,580 (+)	NCBI		Celera
RGSC_v3.1	3	163,769,222 - 163,784,038 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

RAE1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	57,351,255 - 57,379,202 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	57,351,223 - 57,379,211 (+)	Ensembl			hg38	GRCh38
GRCh37	20	55,926,311 - 55,954,258 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	55,359,552 - 55,386,926 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	55,359,723 - 55,386,918	NCBI
Celera	20	52,666,382 - 52,693,760 (+)	NCBI		Celera
Cytogenetic Map	20	q13.31	NCBI
HuRef	20	52,708,342 - 52,735,720 (+)	NCBI		HuRef
CHM1_1	20	55,827,102 - 55,854,476 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	59,128,709 - 59,156,957 (+)	NCBI		T2T-CHM13v2.0

Rae1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	172,841,909 - 172,857,532 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	172,841,910 - 172,857,532 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	173,000,116 - 173,015,739 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	173,000,117 - 173,015,739 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	172,825,638 - 172,841,233 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	172,643,076 - 172,658,671 (+)	NCBI		MGSCv36	mm8
Celera	2	178,965,522 - 178,981,108 (+)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	95.66	NCBI

Rae1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	2,068,431 - 2,084,734 (-)	Ensembl
ChiLan1.0	NW_004955445	2,069,791 - 2,084,210 (-)	NCBI	ChiLan1.0	ChiLan1.0

RAE1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	63,102,341 - 63,129,559 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	63,095,469 - 63,122,678 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	53,691,491 - 53,719,456 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	54,970,065 - 54,997,278 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	54,972,913 - 54,997,273 (+)	Ensembl			panPan2	panpan1.1

RAE1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	42,364,559 - 42,385,209 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	42,345,547 - 42,384,481 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	41,612,165 - 41,632,772 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	43,230,084 - 43,250,699 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	43,211,048 - 43,250,014 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	42,315,596 - 42,335,573 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	42,454,744 - 42,475,358 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	43,112,941 - 43,133,549 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rae1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	183,085,769 - 183,105,515 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936530	200,584 - 220,520 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936530	200,369 - 219,807 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAE1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	57,751,852 - 57,768,591 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	57,751,858 - 57,768,594 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	64,916,069 - 64,932,171 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAE1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	6,744,984 - 6,772,870 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	6,744,982 - 6,772,736 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	54,807,840 - 54,835,141 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rae1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	23,803,292 - 23,825,834 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624741	23,803,325 - 23,825,718 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	63
Count of miRNA genes:	53
Interacting mature miRNAs:	59
Transcripts:	ENSRNOT00000038182
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	141555229	186555229	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141555229	186555229	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	152055202	189428310	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	142898802	187898802	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	141555229	186555229	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	141555229	186555229	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	145335553	189428310	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	151075912	189428310	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	141555229	186555229	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	141555229	186555229	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	161492708	189428310	Rat
1582256	Insul9	Insulin level QTL 9	4.4	0.0016	blood insulin amount (VT:0001560)	absolute change in serum insulin level (CMO:0002038)	3	155759447	189428310	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	139299381	184299381	Rat
1582248	Insul7	Insulin level QTL 7	3.9	0.0041	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	151075912	189428310	Rat
1300161	Rf10	Renal function QTL 10	3.57		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	3	181611379	189428310	Rat
8552791	Vie2	Viral induced encephalitis QTL 2	4.1		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	3	166376089	189428310	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	151075912	189428310	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	161799270	187311134	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	141555229	186555229	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	144575244	189428310	Rat
1582213	Insul6	Insulin level QTL 6	3.7	0.0009	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	3	155759447	189428310	Rat
1598854	Memor10	Memory QTL 10	2		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	3	166376089	189428310	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001033708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235692	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762517	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762518	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC104721	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC105758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000038182 ⟹ ENSRNOP00000029085

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	182,199,852 - 182,213,135 (+)	Ensembl
mRatBN7.2 Ensembl	3	161,779,259 - 161,794,038 (+)	Ensembl
Rnor_6.0 Ensembl	3	171,015,617 - 171,030,384 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094842 ⟹ ENSRNOP00000077776

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	161,779,518 - 161,794,038 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114946 ⟹ ENSRNOP00000087391

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	182,197,459 - 182,212,406 (+)	Ensembl
mRatBN7.2 Ensembl	3	161,779,088 - 161,794,038 (+)	Ensembl

RefSeq Acc Id:

NM_001033708 ⟹ NP_001028880

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	182,197,602 - 182,212,381 (+)	NCBI
mRatBN7.2	3	161,779,259 - 161,794,039 (+)	NCBI
Rnor_6.0	3	171,015,617 - 171,030,385 (+)	NCBI
Rnor_5.0	3	177,081,924 - 177,096,857 (+)	NCBI
RGSC_v3.4	3	163,863,196 - 163,877,975 (+)	RGD
Celera	3	160,972,801 - 160,987,580 (+)	RGD

Sequence:

show sequence

CGCCCCCGTCCCCGCCAGCCGCGCTCCCTCAGGAAAGCCCCCGGCCCGCGTGGGGAAAACTGAG
TCCCTCTCTGCAGCCGGACCCTGTGCGCTCCGCCAGCCAACATGAGTCTGTTTGGAACAACCTC
TGGTTTTGGGACTGGTGGGACCAGCATGTTTGGGAGCACAACCACAGATAACCATAACCCAATG
AAGGATATTGAAGTAACGTCTTCTCCTGATGACAGCATCGGTTGTCTGTCTTTCAGCCCACCAA
CCTTACCAGGGAACTTCCTTATTGCAGGATCGTGGGCTAATGATGTTCGCTGCTGGGAAGTGCA
AGACAGCGGGCAAACCATTCCAAAGGCCCAGCAAATGCATACCGGGCCAGTGCTTGATGTCTGC
TGGAGTGACGATGGGAGCAAAGTGTTCACAGCATCGTGTGACAAGACAGCCAAGATGTGGGACC
TGAACAGCAACCAGGCCATTCAGATAGCACAGCACGATGCTCCCGTTAAGACCATACATTGGAT
CAAAGCCCCAAACTACAGCTGCGTGATGACCGGGAGCTGGGATAAGACCCTGAAGTTTTGGGAT
ACCCGGTCGTCAAATCCTATGATGGTCCTGCAGCTCCCTGAGCGCTGTTACTGTGCAGATGTGA
TCTATCCGATGGCTGTGGTGGCCACTGCAGAAAGGGGCCTGATTGTGTACCAGTTGGAGAACCA
GCCCTCTGAGTTCAGGAGGATAGAGTCTCCACTGAAGCACCAGCATCGGTGTGTGGCTATCTTT
AAAGACAAACAGAACAAGCCAACGGGTTTTGCTCTTGGGAGTATTGAGGGGAGAGTGGCCATTC
ACTACATCAACCCTCCAAATCCGGCCAAAGATAACTTCACCTTCAAATGCCATCGATCCAACGG
TACCAACACTTCTGCTCCTCAAGACATCTATGCAGTGAACGGCATCGCCTTCCACCCTGTCCAT
GGCACCCTGGCCACTGTGGGGTCCGACGGCCGGTTCAGCTTCTGGGACAAAGATGCCAGGACAA
AGCTGAAGACCTCAGAGCAGCTGGACCAGCCCGTGGCAGCGTGTGGCTTCAACCACAACGGGAA
CATATTTGCCTATGCCTCCAGCTACGACTGGTCCAAGGGGCATGAGTTTTATAATCCCCAAAAG
AAAAATTACATTTTCCTGCGTAATGCAGCTGAAGAGCTAAAGCCAAGAAATAAAAAGTAGTGGC
CTGAAGCCGGGGCTGTCGGAGCCCCACCTCCTCTGCACCACCTCTGCCCACACTTGGGCCCTGC
CTGTGGTGTCCACCCCTGGAGGGACTGTGTTCTGTTCCGCATCGGTGCAGCCTCCCGGCGGCTT
GCTGTCTCTCCATTCCACTCCCTGCTGCGGGTTCTCTAAGGGAACTGAGACTCAATGAAGTCGG
GGTCTCGAGGGGATCATGAGCAGCAGTGTGTACTTGACAGCGTTGGGAGGGAACTGCTGATGAG
CCCTGTGGTGTTTTATAATAAAATACTTTGAAGATGGCCTAACTCCATCTTCTCCAACTCCTCA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006235692 ⟹ XP_006235754

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	182,197,432 - 182,212,377 (+)	NCBI
mRatBN7.2	3	161,779,096 - 161,794,048 (+)	NCBI
Rnor_6.0	3	171,015,447 - 171,030,392 (+)	NCBI
Rnor_5.0	3	177,081,924 - 177,096,857 (+)	NCBI

Sequence:

show sequence

CGGAAGTGGCTTGTAGCGCATGCGCTGTGCTTCTGTGGTAACTGGGCAGTTTCCACCGGTTTAA
GACGACTGCGAGGTCTGGGGTCTCCTTGCTGCGCCCCCTCCGCCCCGCGCCAGAGCAGGCTCGT
GGCTTCGGGCCCCGCCGCGTGCGCAACCCTCAGGCGGCCGCGCGCCCCCGTCCCCGCCAGCCGC
GCTCCCTCAGGAAAGCCCCCGGCCCGCGTGGGGAAAACTGAGTCCCTCTCTGCAGCCGGACCCT
GTGCGCTCCGCCAGAGGACAGCTTTGAGTTCTCTGGGGATCACACTCATGTCTCCAGGCTTGTG
CACCGGGGGTCTTCGCTGTCTGAGCCGACCGGCCAGCCCCAGAGCAGGCCTGGAGAGTGCGTGC
TGCGTTTTCACCACAGCTGGAAGCTGAAGCATGGCAACCAACATGAGTCTGTTTGGAACAACCT
CTGGTTTTGGGACTGGTGGGACCAGCATGTTTGGGAGCACAACCACAGATAACCATAACCCAAT
GAAGGATATTGAAGTAACGTCTTCTCCTGATGACAGCATCGGTTGTCTGTCTTTCAGCCCACCA
ACCTTACCAGGGAACTTCCTTATTGCAGGATCGTGGGCTAATGATGTTCGCTGCTGGGAAGTGC
AAGACAGCGGGCAAACCATTCCAAAGGCCCAGCAAATGCATACCGGGCCAGTGCTTGATGTCTG
CTGGAGTGACGATGGGAGCAAAGTGTTCACAGCATCGTGTGACAAGACAGCCAAGATGTGGGAC
CTGAACAGCAACCAGGCCATTCAGATAGCACAGCACGATGCTCCCGTTAAGACCATACATTGGA
TCAAAGCCCCAAACTACAGCTGCGTGATGACCGGGAGCTGGGATAAGACCCTGAAGTTTTGGGA
TACCCGGTCGTCAAATCCTATGATGGTCCTGCAGCTCCCTGAGCGCTGTTACTGTGCAGATGTG
ATCTATCCGATGGCTGTGGTGGCCACTGCAGAAAGGGGCCTGATTGTGTACCAGTTGGAGAACC
AGCCCTCTGAGTTCAGGAGGATAGAGTCTCCACTGAAGCACCAGCATCGGTGTGTGGCTATCTT
TAAAGACAAACAGAACAAGCCAACGGGTTTTGCTCTTGGGAGTATTGAGGGGAGAGTGGCCATT
CACTACATCAACCCTCCAAATCCGGCCAAAGATAACTTCACCTTCAAATGCCATCGATCCAACG
GTACCAACACTTCTGCTCCTCAAGACATCTATGCAGTGAACGGCATCGCCTTCCACCCTGTCCA
TGGCACCCTGGCCACTGTGGGGTCCGACGGCCGGTTCAGCTTCTGGGACAAAGATGCCAGGACA
AAGCTGAAGACCTCAGAGCAGCTGGACCAGCCCGTGGCAGCGTGTGGCTTCAACCACAACGGGA
ACATATTTGCCTATGCCTCCAGCTACGACTGGTCCAAGGGGCATGAGTTTTATAATCCCCAAAA
GAAAAATTACATTTTCCTGCGTAATGCAGCTGAAGAGCTAAAGCCAAGAAATAAAAAGTAGTGG
CCTGAAGCCGGGGCTGTCGGAGCCCCACCTCCTCTGCACCACCTCTGCCCACACTTGGGCCCTG
CCTGTGGTGTCCACCCCTGGAGGGACTGTGTTCTGTTCCGCATCGGTGCAGCCTCCCGGCGGCT
TGCTGTCTCTCCATTCCACTCCCTGCTGCGGGTTCTCTAAGGGAACTGAGACTCAATGAAGTCG
GGGTCTCGAGGGGATCATGAGCAGCAGTGTGTACTTGACAGCGTTGGGAGGGAACTGCTGATGA
GCCCTGTGGTGTTTTATAATAAAATACTTTGAAGATGGCCTAACTCCATCTTCTCCAACTCCTC
AGGAAATA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001028880	(Get FASTA)	NCBI Sequence Viewer
	XP_006235754	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI04722	(Get FASTA)	NCBI Sequence Viewer
	AAI05759	(Get FASTA)	NCBI Sequence Viewer
	EDL85129	(Get FASTA)	NCBI Sequence Viewer
	EDL85130	(Get FASTA)	NCBI Sequence Viewer
	EDL85131	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000029085
	ENSRNOP00000029085.4
	ENSRNOP00000087391
GenBank Protein	Q3SWS8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001028880 ⟸ NM_001033708

- UniProtKB:

Q3SWS8 (UniProtKB/Swiss-Prot), A6KKY5 (UniProtKB/TrEMBL), A0A8I5XWH8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSLFGTTSGFGTGGTSMFGSTTTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWAN
DVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSNQAIQIAQHDA
PVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGL
IVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFT
FKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPVAA
CGFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAEELKPRNKK

hide sequence

RefSeq Acc Id:	XP_006235754 ⟸ XM_006235692
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A498 (UniProtKB/TrEMBL), A0A8I5XWH8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATNMSLFGTTSGFGTGGTSMFGSTTTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAG SWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSNQAIQIA QHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATA ERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAK DNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQ PVAACGFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAEELKPRNKK hide sequence

Ensembl Acc Id:

ENSRNOP00000029085 ⟸ ENSRNOT00000038182

Ensembl Acc Id:

ENSRNOP00000087391 ⟸ ENSRNOT00000114946

Ensembl Acc Id:

ENSRNOP00000077776 ⟸ ENSRNOT00000094842

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q3SWS8-F1-model_v2	AlphaFold	Q3SWS8	1-368	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311540	AgrOrtholog
BioCyc Gene	G2FUF-46523	BioCyc
Ensembl Genes	ENSRNOG00000021295	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000038182	ENTREZGENE
	ENSRNOT00000038182.6	UniProtKB/Swiss-Prot
	ENSRNOT00000114946	ENTREZGENE
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:5623260	IMAGE-MGC_LOAD
	IMAGE:7383476	IMAGE-MGC_LOAD
InterPro	G-protein_beta_WD-40_rep	UniProtKB/Swiss-Prot
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot
	WD40_repeat	UniProtKB/Swiss-Prot
	WD40_repeat_CS	UniProtKB/Swiss-Prot
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:362281	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:124870	IMAGE-MGC_LOAD
	MGC:125198	IMAGE-MGC_LOAD
NCBI Gene	362281	ENTREZGENE
PANTHER	MRNA EXPORT FACTOR AND BUB3	UniProtKB/Swiss-Prot
Pfam	WD40	UniProtKB/Swiss-Prot
PhenoGen	Rae1	PhenoGen
PRINTS	GPROTEINBRPT	UniProtKB/Swiss-Prot
PROSITE	WD_REPEATS_1	UniProtKB/Swiss-Prot
	WD_REPEATS_2	UniProtKB/Swiss-Prot
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000021295	RatGTEx
SMART	WD40	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot
UniProt	A0A8I5XWH8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A498	ENTREZGENE, UniProtKB/TrEMBL
	A6KKY5	ENTREZGENE, UniProtKB/TrEMBL
	A6KKY6_RAT	UniProtKB/TrEMBL
	A6KKY7_RAT	UniProtKB/TrEMBL
	Q3SWS8	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-09-16	Rae1	ribonucleic acid export 1	Rae1	RAE1 RNA export 1 homolog (S. pombe)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Rae1	RAE1 RNA export 1 homolog (S. pombe)	Rae1_predicted	RAE1 RNA export 1 homolog (S. pombe) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Rae1_predicted	RAE1 RNA export 1 homolog (S. pombe) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)