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Gene: Slc16a12 (solute carrier family 16, member 12) Rattus norvegicus

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Symbol:

Slc16a12

Name:

solute carrier family 16, member 12

RGD ID:

1311468

Description:

Enables creatine transmembrane transporter activity. Involved in creatine transmembrane transport and creatinine metabolic process. Located in basolateral plasma membrane. Human ortholog(s) of this gene implicated in cataract 47. Orthologous to human SLC16A12 (solute carrier family 16 member 12); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC309525; MCT 12; monocarboxylate transporter 12; RGD1311468; similar to expressed sequence AW210596; solute carrier family 16 (monocarboxylic acid transporters), member 12; solute carrier family 16, member 12 (monocarboxylic acid transporter 12)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC16A12 (solute carrier family 16 member 12)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Slc16a12 (solute carrier family 16 (monocarboxylic acid transporters), member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc16a12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC16A12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC16A12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc16a12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC16A12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC16A12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc16a12 (solute carrier family 16 member 12)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HNRNPA3 (heterogeneous nuclear ribonucleoprotein A3)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Slc16a12 (solute carrier family 16 (monocarboxylic acid transporters), member 12)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SLC16A12 (solute carrier family 16 member 12)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc16a12a (solute carrier family 16 member 12a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	slc16a12b (solute carrier family 16 member 12b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11665	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	MCH5	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ESBP6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ESBP6	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	MCH2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mct-2	Alliance	DIOPT (OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG14196	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	MCH4	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Mct1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA)
Drosophila melanogaster (fruit fly):	Mct1	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mct-6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mct-6	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8389	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	mct-1	Alliance	DIOPT (OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mct-5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mct-5	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8028	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG8034	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG8051	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	mct-3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	out	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Sln	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	slc16a12	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Slc16a12^{Tn(sb-T2/Bart3)2.298Mcwi}

Genetic Models:

F344-Slc16a12^{Tn(sb-T2/Bart3)2.298Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	241,597,165 - 241,674,821 (-)	NCBI		GRCr8
GRCr8 Ensembl	1	241,599,066 - 241,674,743 (-)	Ensembl		GRCr8 Ensembl
mRatBN7.2	1	232,184,004 - 232,262,170 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	232,185,907 - 232,262,141 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	240,579,603 - 240,608,453 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	247,498,691 - 247,521,337 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	240,336,893 - 240,359,535 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	252,976,071 - 253,054,500 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	252,976,644 - 253,000,760 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	260,197,556 - 260,275,962 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	238,643,040 - 238,665,699 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	229,298,962 - 229,321,612 (-)	NCBI		Celera
RGSC_v3.1	1	238,807,343 - 238,830,600 (-)	NCBI
Cytogenetic Map	1	q53	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autoimmune lymphoproliferative syndrome (ISO)

cataract (ISO)

cataract 47 (ISO)

coloboma (ISO)

Wolman disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

2-palmitoylglycerol (ISO)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bilirubin IXalpha (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

CGP 52608 (ISO)

chloropicrin (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cyproconazole (ISO)

dexamethasone (ISO)

doxorubicin (ISO)

endosulfan (EXP,ISO)

epoxiconazole (ISO)

flutamide (EXP)

fonofos (ISO)

hydrogen peroxide (ISO)

hydroxyurea (ISO)

indometacin (ISO)

inulin (ISO)

N-methyl-N-nitrosourea (ISO)

nickel sulfate (ISO)

O-methyleugenol (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (EXP)

parathion (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

potassium dichromate (ISO)

propiconazole (ISO)

resveratrol (ISO)

rifampicin (ISO)

senecionine (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

succimer (ISO)

terbufos (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triclosan (ISO)

trimellitic anhydride (ISO)

valproic acid (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

creatine transmembrane transport (IBA,IDA,IEA,ISO)

creatinine metabolic process (IDA)

transmembrane transport (IEA)

Cellular Component

basolateral plasma membrane (IDA,IEA,ISO)

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

Molecular Function

creatine transmembrane transporter activity (IDA,IEA,ISO)

protein binding (ISO)

transmembrane transporter activity (IBA,IEA)

uniporter activity (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Contribution of monocarboxylate transporter 12 to blood supply of creatine on the sinusoidal membrane of the hepatocytes.	Jomura R, etal., Am J Physiol Gastrointest Liver Physiol. 2021 Aug 1;321(2):G113-G122. doi: 10.1152/ajpgi.00143.2021. Epub 2021 Jun 2.
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:21778275	PMID:23578822	PMID:32781157	PMID:33459166

Genomics

Comparative Map Data

Slc16a12
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	241,597,165 - 241,674,821 (-)	NCBI		GRCr8
GRCr8 Ensembl	1	241,599,066 - 241,674,743 (-)	Ensembl		GRCr8 Ensembl
mRatBN7.2	1	232,184,004 - 232,262,170 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	232,185,907 - 232,262,141 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	240,579,603 - 240,608,453 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	247,498,691 - 247,521,337 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	240,336,893 - 240,359,535 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	252,976,071 - 253,054,500 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	252,976,644 - 253,000,760 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	260,197,556 - 260,275,962 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	238,643,040 - 238,665,699 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	229,298,962 - 229,321,612 (-)	NCBI		Celera
RGSC_v3.1	1	238,807,343 - 238,830,600 (-)	NCBI
Cytogenetic Map	1	q53	NCBI

SLC16A12
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	89,430,299 - 89,556,704 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	89,430,299 - 89,556,641 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	91,190,056 - 91,295,351 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	91,180,036 - 91,285,293 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	10	84,936,860 - 85,042,126 (-)	NCBI		Celera
Cytogenetic Map	10	q23.31	NCBI
HuRef	10	84,824,228 - 84,929,593 (-)	NCBI		HuRef
CHM1_1	10	91,472,067 - 91,577,412 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	90,314,133 - 90,419,429 (-)	NCBI		T2T-CHM13v2.0

Slc16a12
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	34,645,801 - 34,725,223 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	34,645,803 - 34,724,689 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	34,668,401 - 34,747,493 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	34,668,403 - 34,747,289 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	34,742,896 - 34,821,601 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	34,734,403 - 34,813,108 (-)	NCBI		MGSCv36	mm8
Celera	19	35,442,689 - 35,521,028 (-)	NCBI		Celera
Cytogenetic Map	19	C1	NCBI
cM Map	19	29.79	NCBI

Slc16a12
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	3,509,142 - 3,560,138 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	3,474,814 - 3,560,138 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC16A12
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	101,446,803 - 101,481,472 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	101,452,146 - 101,486,786 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	86,155,527 - 86,187,917 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	89,696,148 - 89,727,585 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	89,696,148 - 89,727,585 (-)	Ensembl	panpan1.1		panPan2

SLC16A12
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	4,343,773 - 4,430,653 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	4,345,546 - 4,421,234 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	4,579,217 - 4,664,998 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	4,565,289 - 4,652,174 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	4,567,687 - 4,651,465 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	4,323,134 - 4,402,863 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	4,365,926 - 4,445,342 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	4,501,245 - 4,580,912 (-)	NCBI		UU_Cfam_GSD_1.0

Slc16a12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	43,114,853 - 43,133,513 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936601	4,747,489 - 4,763,697 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936601	4,685,215 - 4,766,116 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC16A12
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	101,273,996 - 101,368,132 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	101,273,977 - 101,368,350 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	110,262,470 - 110,354,305 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC16A12
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	82,817,476 - 82,917,004 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	82,818,994 - 82,916,837 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	43,493,620 - 43,592,283 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc16a12
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	312,039 - 365,915 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	312,039 - 405,432 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc16a12
338 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	54
Count of miRNA genes:	48
Interacting mature miRNAs:	53
Transcripts:	ENSRNOT00000030024
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8693637	Alc29	Alcohol consumption QTL 29	2.7	0.258	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	1	217412367	243666627	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1357335	Bw39	Body weight QTL 39	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	1	207243873	252243873	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	186658830	266453731	Rat
2293674	Bss39	Bone structure and strength QTL 39	7.1	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	1	210980612	255980612	Rat
61455	Niddm7	Non-insulin dependent diabetes mellitus QTL 7	5.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	223964326	248681945	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	226175591	270518180	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	205233991	267096252	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	218829748	263829748	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	186658830	266453731	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	176288899	270518180	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
2293694	Bss38	Bone structure and strength QTL 38	7.05	0.0001	femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	1	210980612	255980612	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	237995023	269633915	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	233480549	270108840	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	200449456	256003563	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	234540191	270518180	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	146080545	243492863	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	233480549	270108840	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	207163993	269633915	Rat
2300175	Bmd40	Bone mineral density QTL 40	15.4	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	1	210980612	255980612	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
724538	Kidm1	Kidney mass QTL 1	3.2		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	223134011	262090599	Rat
2293655	Bss36	Bone structure and strength QTL 36	10.66	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	210980612	255980612	Rat
1298084	Thym4	Thymus enlargement QTL 4	10.68		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	207243873	252243873	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
2314011	Gluco56	Glucose level QTL 56			blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	209203273	254203273	Rat
8552891	Epfw5	Epididymal fat weight QTL 5	4.4		epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	1	202543537	247543537	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	225108840	270108840	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	228180370	266453608	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
1358292	Cm37	Cardiac mass QTL 37	6.2	8e-07	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	1	205674651	250674651	Rat
61376	Bp42	Blood pressure QTL 42	23.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	207243873	252243873	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	208479811	269633915	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	224633915	269633915	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	232312773	270518180	Rat
2316896	Gluco57	Glucose level QTL 57	7.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	238398865	255849249	Rat
1358916	Kidm22	Kidney mass QTL 22	3.32		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	212738576	257738576	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	194786607	262083703	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	188241285	250779312	Rat
2292218	Kidm35	Kidney mass QTL 35			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	208798288	253798288	Rat
61400	Niddm1	Non-insulin dependent diabetes mellitus QTL 1	11		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	228180243	255849249	Rat
61403	Niddm4	Non-insulin dependent diabetes mellitus QTL 4			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	201464383	246464383	Rat
1641926	Teswt2	Testicular weight QTL 2	2.82		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	1	203675682	248675682	Rat
631658	Cm7	Cardiac mass QTL 7	5.32	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	1	205674651	250674651	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
2293700	Bmd27	Bone mineral density QTL 27	6.6	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	210980612	255980612	Rat
2293701	Bmd34	Bone mineral density QTL 34	8.3	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	1	210980612	255980612	Rat
7387289	Uae45	Urinary albumin excretion QTL 45	2.86	0.0021	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	233204160	270518180	Rat
1600374	Mcs17	Mammary carcinoma susceptibility QTL 17	3		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	207099883	252099883	Rat
1581544	Rf52	Renal function QTL 52		0.05	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	1	241569529	269633915	Rat
1600363	Hc6	Hypercalciuria QTL 6	2.7		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	210980612	255980612	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	185857683	270518180	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	226175591	270518180	Rat
631669	Iddm9	Insulin dependent diabetes mellitus QTL 9	2.8	0.039	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	233349180	270518180	Rat
7394701	Uae46	Urinary albumin excretion QTL 46	3.6	0.0056	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	210980612	255980612	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	228174566	270518180	Rat

Markers in Region

RH139695

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	232,261,919 - 232,262,109 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	253,054,145 - 253,054,334	NCBI	Rnor6.0
Rnor_5.0	1	260,275,712 - 260,275,901	UniSTS	Rnor5.0
RGSC_v3.4	1	238,718,730 - 238,718,919	UniSTS	RGSC3.4
Celera	1	229,374,607 - 229,374,796	UniSTS
RH 3.4 Map	4	511.02	UniSTS
Cytogenetic Map	1	q52	UniSTS

Genetic Models

This gene Slc16a12 is modified in the following models/strains:

F344-Slc16a12^{Tn(sb-T2/Bart3)2.298Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	11	49	113	91	90	59	25	59	6	218	97	11	93	45	60	31	15	15

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC098155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC128768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211380	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000030024 ⟹ ENSRNOP00000038838

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	241,599,066 - 241,674,111 (-)	Ensembl
mRatBN7.2 Ensembl	1	232,185,907 - 232,262,141 (-)	Ensembl
Rnor_6.0 Ensembl	1	252,976,644 - 253,000,760 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000167047 ⟹ ENSRNOP00000104843

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	241,599,066 - 241,674,743 (-)	Ensembl

RefSeq Acc Id:

NM_001191637 ⟹ NP_001178566

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	241,599,066 - 241,621,716 (-)	NCBI
mRatBN7.2	1	232,185,907 - 232,208,555 (-)	NCBI
Rnor_6.0	1	252,977,974 - 253,000,624 (-)	NCBI
Rnor_5.0	1	260,197,556 - 260,275,962 (-)	NCBI
Celera	1	229,298,962 - 229,321,612 (-)	NCBI

Sequence:

show sequence

ATGACGAAGATAACTAGAGTTGGTTCCGCATCCCCTCCAGATGGAGGCTGGGGATGGATGATTG
TGGCCGGCTGCTTTCTTGTTACCATCTGCACCCGGGCAGTCACCAGGTGTATCTCCATATTTTT
TGTGGAGTTTCAGACGTACTTTGCTCAGGATTATTCCCAAACAGCATGGATCCATTCCATTGTA
GACTGCATGACAATGCTCTGTGCTCCGCTTGGGAGTGTTGTCAGTAACCAATTATCCTGTCAAG
CGGGGATCATGCTGGGTGGCTTGCTGGCATCTACTGGTCTCATCCTGGGCTCATTTGCCACCAG
TTTGAAGCACCTCTACCTCAGTCTGGGAGTTCTCACAGGTCTTGGATTTGCACTTTGTTACTCC
CCAGCAATTGCCATGGTGGGCAAGTACTTCAGCAGGCGGAAAGCCTTCGCTTACGGGATTGCCA
TGTCAGGCAGTGGCATTGGTACCTTCATCCTGGCCCCTGTGGTTCAGCTCCTCATTGAACAGTT
CTCCTGGCGAGGAGCACTGCTCATTCTTGGTGGGTTCGTTCTGAATCTCTGCGTCTGCGGCGCG
CTGATGCGTCCAATTACCCTTAAAGAGGACCCGTCAGGCCCAGAGAAGAGTCACGACCGTGACG
CTCAGAGAGAAGACTGTAAGCAGGCATCTCCCTATTCACCTTTGACCAAAGAATGGACAGAGAC
CCGTCTTTGCTGCTCTTTGCAGCAAGGATACGGCTTTTTACTGATGTCAGACTTCGTCGTGCTG
GCTGTCTCTGTTCTGTTCATGGCCTACGGCTGCAGCCCTCTCTTTGTGTACCTGGTGCCTTATG
CTTTGAGTGTCGGAGTGAGTCACCATCAAGCTGCTTTCCTCATGTCCATCCTCGGAGTGATTGA
TATTGTCGGCAACATCACGTTTGGCTGGCTAACTGACAGAAGGTGTCTGAAGAATTACCGATAT
GTTTGCTACCTCTTTGCTGTGGCACTAGATGGGCTGTGCTATCTGTGTCTCCCAATGCTTCAAA
GCTTCCCCCTTCTTGTGCCTTTCTCTTGTACCTTTGGCTACTTCGACGGAGCCTACGTTACCTT
GATCCCAGTAGTGACTGCAGAGATAGTAGGGACCACCTCTTTGTCATCAGCACTTGGCGTGGTC
TACTTCCTCCATGCAGTGCCATACTTGGTGAGCCCACCCATTGCAGGATGGCTGGTGGACACGA
CGGGCAGCTATACTGCAGCCTTCCTTCTTTGTGGATTTGCCATGATATTTAGTTCCATCCTGCT
TGGCTTTGCCAAAATTGCAAAAAGAATGAAAAGAACACAGGTGCCCTTCCTGGTCAAAGACTCA
GATCCCAAGCTGCATCTGTGGACCAATGGATCAGTGGCCTACTCTATAGCGAAGGAGTTAGATC
AGAAAGATGAGGAATCCCTGGCTAAAGCTAGGACTGGTTGCAATCTCACATGACCTGTGTGGCC
TTGTCCTGGGAATCTGCAAGGCTGGTGGATACCAGGCCACCAGGTTGTTCACAGTCTGGAAATA
TTTTATTTTGACAGAGTATCACCTCCCAAGTAAATTATTAATACTGTTTTGTTAACATATTTAT
ATGGGGACAATAATGAGCAACAAAGAAATCTGGAGTTAGCCTGGAGTTTTCTCATTCAGGATTT
GTACTCACTACAAACTTAGCTCTGGGAGAAGGGCAGGACACAGTTGACAGGGTCAGTTGTATTT
CAGGACAACTCTAAGCAGAGGCCACTGTGAAGAGTTTTCATAAAATCTGCCCCACCCCCTCATT
CTGAACAGAAGCAGTGGTGGTTGTGCTGGCAGTGGGGATGCAGAGGTGACTTGAGAACAGAGCG
CCTCAATGTTTAGAGTGGCA

hide sequence

RefSeq Acc Id:

XM_017589300 ⟹ XP_017444789

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	241,597,165 - 241,674,078 (-)	NCBI
mRatBN7.2	1	232,186,279 - 232,262,170 (-)	NCBI
Rnor_6.0	1	252,978,244 - 253,054,500 (-)	NCBI

Sequence:

show sequence

GGGGATGGCTAGCTAGGAAACTGCAGGACAGATGCCTCCTGGAGGGCGGGGCAAACACCATTTA
CCCTCCACTGTTAAGGAACCTGGCACCCCATTTTTTCTTCAGCAGGAGCAAACTTTGTTTTTAT
TTTATTGAGAAACTGAGACCAAGTGAACTGTTTAAAGTCATAGAGTTTGCGAGCGAGTTGAACT
CAAGTCCTTAGGACTGATTGATGTGTGCAGTGGTCTGACCAGGGTCCTGGTCCTTGCCAGATGC
CGGTGCAGGAGACTTTGAACAGCTTCTACTCTCTGACCATTCAGGGACATAGTCTTCTGGAGAA
CACCCAGGCACTCCTTTAGTGTAGGTCCCAGGCACACAGGGCTGTTCCAGAGAGAGCCCTGCAA
GTCCCTAGTGGGCTGGCTCGTGACTCGGCGGGCCGGCCGGGCCGGAGCATTACATAACCTGGAG
GCGCCCCTCCTCCGTGGCCGAGCCCCCAGCGCAGAGCGGATCCGGGGACAAGGCCAGTCTGGCA
GCAGGGCAGAGTCACCCTCGGGGCTGGCGTCACTGAGAGCCTTGGTTCTCCGGGGCGGGGCGGT
GGGATCTCCTCAGTGACAGTGTCCGGCGGGCTCTGCCTGTGGCCCCGGCCCCTACGGCGCCTCC
GCCCCGTGCGCACCCCGCCCCTCGGCCGGACCGGACTCCAGGGGCCGTGGGAAGGGGCCGCCGT
GCAGGGGGCATGTGGGCTCACCGTCGCCAGCTCTGCAGCTGTCCCCGCGAGTGCAAGCTGATGA
TTCAGCGTTCCGAACCACTCGCTCGCGTTTTGTCTGGACGCTGGTTCGTTCTTCCCAGCTTTGC
TGAGAGCTATGTGGGCAATTCCAGCGGCTCTGCTGACCTAGTCCAGAAGGAAAAATCTTCAGGC
TTGCCAAGTTCAGGAAGACCCCGTGGCTACAGATGGGCAGTAATCCCTGTGCCAGGTAGCATCC
TGAACCAACTTTGAGGATCAACAGGAAGTTGCTGGGTAGCAACCACTGAGGATCCTAACTTACT
GCTGCAGTGACCTGGAAAGAGAAGAAAACCAAAATTGCAACCATGACGAAGATAACTAGAGTTG
GTTCCGCATCCCCTCCAGATGGAGGCTGGGGATGGATGATTGTGGCCGGCTGCTTTCTTGTTAC
CATCTGCACCCGGGCAGTCACCAGGTGTATCTCCATATTTTTTGTGGAGTTTCAGACGTACTTT
GCTCAGGATTATTCCCAAACAGCATGGATCCATTCCATTGTAGACTGCATGACAATGCTCTGTG
CTCCGCTTGGGAGTGTTGTCAGTAACCAATTATCCTGTCAAGCGGGGATCATGCTGGGTGGCTT
GCTGGCATCTACTGGTCTCATCCTGGGCTCATTTGCCACCAGTTTGAAGCACCTCTACCTCAGT
CTGGGAGTTCTCACAGGTCTTGGATTTGCACTTTGTTACTCCCCAGCAATTGCCATGGTGGGCA
AGTACTTCAGCAGGCGGAAAGCCTTCGCTTACGGGATTGCCATGTCAGGCAGTGGCATTGGTAC
CTTCATCCTGGCCCCTGTGGTTCAGCTCCTCATTGAACAGTTCTCCTGGCGAGGAGCACTGCTC
ATTCTTGGTGGGTTCGTTCTGAATCTCTGCGTCTGCGGCGCGCTGATGCGTCCAATTACCCTTA
AAGAGGACCCGTCAGGCCCAGAGAAGAGTCACGACCGTGACGCTCAGAGAGAAGACTGTAAGCA
GGCATCTCCCTATTCACCTTTGACCAAAGAATGGACAGAGACCCGTCTTTGCTGCTCTTTGCAG
CAAGGATACGGCTTTTTACTGATGTCAGACTTCGTCGTGCTGGCTGTCTCTGTTCTGTTCATGG
CCTACGGCTGCAGCCCTCTCTTTGTGTACCTGGTGCCTTATGCTTTGAGTGTCGGAGTGAGTCA
CCATCAAGCTGCTTTCCTCATGTCCATCCTCGGAGTGATTGATATTGTCGGCAACATCACGTTT
GGCTGGCTAACTGACAGAAGGTGTCTGAAGAATTACCGATATGTTTGCTACCTCTTTGCTGTGG
CACTAGATGGGCTGTGCTATCTGTGTCTCCCAATGCTTCAAAGCTTCCCCCTTCTTGTGCCTTT
CTCTTGTACCTTTGGCTACTTCGACGGAGCCTACGTTACCTTGATCCCAGTAGTGACTGCAGAG
ATAGTAGGGACCACCTCTTTGTCATCAGCACTTGGCGTGGTCTACTTCCTCCATGCAGTGCCAT
ACTTGGTGAGCCCACCCATTGCAGGATGGCTGGTGGACACGACGGGCAGCTATACTGCAGCCTT
CCTTCTTTGTGGATTTGCCATGATATTTAGTTCCATCCTGCTTGGCTTTGCCAAAATTGCAAAA
AGAATGAAAAGAACACAGGTGCCCTTCCTGGTCAAAGACTCAGATCCCAAGCTGCATCTGTGGA
CCAATGGATCAGTGGCCTACTCTATAGCGAAGGAGTTAGATCAGAAAGATGAGGAATCCCTGGC
TAAAGCTAGGACTGGTTGCAATCTCACATGACCTGTGTGGCCTTGTCCTGGGAATCTGCAAGGC
TGGTGGATACCAGGCCACCAGGTTGTTCACAGTCTGGAAATATTTTATTTTGACAGAGTATCAC
CTCCCAAGTAAATTATTAATACTGTTTTGTTAACATATTTATATGGGG

hide sequence

RefSeq Acc Id:

XM_017589301 ⟹ XP_017444790

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	241,597,165 - 241,674,821 (-)	NCBI
mRatBN7.2	1	232,184,004 - 232,262,170 (-)	NCBI
Rnor_6.0	1	252,978,244 - 253,054,500 (-)	NCBI

Sequence:

show sequence

GGGGATGGCTAGCTAGGAAACTGCAGGACAGATGCCTCCTGGAGGGCGGGGCAAACACCATTTA
CCCTCCACTGTTAAGGAACCTGGCACCCCATTTTTTCTTCAGCAGGAGCAAACTTTGTTTTTAT
TTTATTGAGAAACTGAGACCAAGTGAACTGTTTAAAGTCATAGAGTTTGCGAGCGAGTTGAACT
CAAGTCCTTAGGACTGATTGATGTGTGCAGTGGTCTGACCAGGGTCCTGGTCCTTGCCAGATGC
CGGTGCAGGAGACTTTGAACAGCTTCTACTCTCTGACCATTCAGGGACATAGTCTTCTGGAGAA
CACCCAGGCACTCCTTTAGTGTAGGTCCCAGGCACACAGGGCTGTTCCAGAGAGAGCCCTGCAA
GTCCCTAGTGGGCTGGCTCGTGACTCGGCGGGCCGGCCGGGCCGGAGCATTACATAACCTGGAG
GCGCCCCTCCTCCGTGGCCGAGCCCCCAGCGCAGAGCGGATCCGGGGACAAGGCCAGTCTGGCA
GCAGGGCAGAGTCACCCTCGGGGCTGGCGTCACTGAGAGCCTTGGTTCTCCGGGGCGGGGCGGT
GGGATCTCCTCAGTGACAGTGTCCGGCGGGCTCTGCCTGTGGCCCCGGCCCCTACGGCGCCTCC
GCCCCGTGCGCACCCCGCCCCTCGGCCGGACCGGACTCCAGGGGCCGTGGGAAGGGGCCGCCGT
GCAGGGGGCATGTGGGCTCACCGTCGCCAGCTCTGCAGCTGTCCCCGCGAGATGGGCAGTAATC
CCTGTGCCAGGTAGCATCCTGAACCAACTTTGAGGATCAACAGGAAGTTGCTGGGTAGCAACCA
CTGAGGATCCTAACTTACTGCTGCAGTGACCTGGAAAGAGAAGAAAACCAAAATTGCAACCATG
ACGAAGATAACTAGAGTTGGTTCCGCATCCCCTCCAGATGGAGGCTGGGGATGGATGATTGTGG
CCGGCTGCTTTCTTGTTACCATCTGCACCCGGGCAGTCACCAGGTGTATCTCCATATTTTTTGT
GGAGTTTCAGACGTACTTTGCTCAGGATTATTCCCAAACAGCATGGATCCATTCCATTGTAGAC
TGCATGACAATGCTCTGTGCTCCGCTTGGGAGTGTTGTCAGTAACCAATTATCCTGTCAAGCGG
GGATCATGCTGGGTGGCTTGCTGGCATCTACTGGTCTCATCCTGGGCTCATTTGCCACCAGTTT
GAAGCACCTCTACCTCAGTCTGGGAGTTCTCACAGGTCTTGGATTTGCACTTTGTTACTCCCCA
GCAATTGCCATGGTGGGCAAGTACTTCAGCAGGCGGAAAGCCTTCGCTTACGGGATTGCCATGT
CAGGCAGTGGCATTGGTACCTTCATCCTGGCCCCTGTGGTTCAGCTCCTCATTGAACAGTTCTC
CTGGCGAGGAGCACTGCTCATTCTTGGTGGGTTCGTTCTGAATCTCTGCGTCTGCGGCGCGCTG
ATGCGTCCAATTACCCTTAAAGAGGACCCGTCAGGCCCAGAGAAGAGTCACGACCGTGACGCTC
AGAGAGAAGACTGTAAGCAGGCATCTCCCTATTCACCTTTGACCAAAGAATGGACAGAGACCCG
TCTTTGCTGCTCTTTGCAGCAAGGATACGGCTTTTTACTGATGTCAGACTTCGTCGTGCTGGCT
GTCTCTGTTCTGTTCATGGCCTACGGCTGCAGCCCTCTCTTTGTGTACCTGGTGCCTTATGCTT
TGAGTGTCGGAGTGAGTCACCATCAAGCTGCTTTCCTCATGTCCATCCTCGGAGTGATTGATAT
TGTCGGCAACATCACGTTTGGCTGGCTAACTGACAGAAGGTGTCTGAAGAATTACCGATATGTT
TGCTACCTCTTTGCTGTGGCACTAGATGGGCTGTGCTATCTGTGTCTCCCAATGCTTCAAAGCT
TCCCCCTTCTTGTGCCTTTCTCTTGTACCTTTGGCTACTTCGACGGAGCCTACGTTACCTTGAT
CCCAGTAGTGACTGCAGAGATAGTAGGGACCACCTCTTTGTCATCAGCACTTGGCGTGGTCTAC
TTCCTCCATGCAGTGCCATACTTGGTGAGCCCACCCATTGCAGGATGGCTGGTGGACACGACGG
GCAGCTATACTGCAGCCTTCCTTCTTTGTGGATTTGCCATGATATTTAGTTCCATCCTGCTTGG
CTTTGCCAAAATTGCAAAAAGAATGAAAAGAACACAGGTGCCCTTCCTGGTCAAAGACTCAGAT
CCCAAGCTGCATCTGTGGACCAATGGATCAGTGGCCTACTCTATAGCGAAGGAGTTAGATCAGA
AAGATGAGGAATCCCTGGCTAAAGCTAGGACTGGTTGCAATCTCACATGACCTGTGTGGCCTTG
TCCTGGGAATCTGCAAGGCTGGTGGATACCAGGCCACCAGGTTGTTCACAGTCTGGAAATATTT
TATTTTGACAGAGTATCACCTCCCAAGTAAATTATTAATACTGTTTTGTTAACATATTTATATG
GGG

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Protein Sequences


Protein RefSeqs	NP_001178566	(Get FASTA)	NCBI Sequence Viewer
	NP_001424503	(Get FASTA)	NCBI Sequence Viewer
	XP_017444789	(Get FASTA)	NCBI Sequence Viewer
	XP_017444790	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D4A734	(Get FASTA)	NCBI Sequence Viewer
	EDM13169	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000038838
	ENSRNOP00000038838.3
	ENSRNOP00000104843

RefSeq Acc Id:

NP_001178566 ⟸ NM_001191637

- UniProtKB:

D4A734 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIV
DCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYS
PAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGA
LMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVL
AVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRY
VCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVV
YFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVKDS
DPKLHLWTNGSVAYSIAKELDQKDEESLAKARTGCNLT

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RefSeq Acc Id:

XP_017444790 ⟸ XM_017589301

- Peptide Label:

isoform X1

- Sequence:

show sequence

MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIV
DCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYS
PAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGA
LMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVL
AVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRY
VCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVV
YFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVKDS
DPKLHLWTNGSVAYSIAKELDQKDEESLAKARTGCNLT

hide sequence

RefSeq Acc Id:

XP_017444789 ⟸ XM_017589300

- Peptide Label:

isoform X1

- Sequence:

show sequence

MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIV
DCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYS
PAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGA
LMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVL
AVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRY
VCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVV
YFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVKDS
DPKLHLWTNGSVAYSIAKELDQKDEESLAKARTGCNLT

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Ensembl Acc Id:

ENSRNOP00000038838 ⟸ ENSRNOT00000030024

Ensembl Acc Id:

ENSRNOP00000104843 ⟸ ENSRNOT00000167047

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A734-F1-model_v2	AlphaFold	D4A734	1-486	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311468	AgrOrtholog
BioCyc Gene	G2FUF-55866	BioCyc
Ensembl Genes	ENSRNOG00000021916	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000030024	ENTREZGENE
	ENSRNOT00000030024.6	UniProtKB/Swiss-Prot
	ENSRNOT00000167047	ENTREZGENE
Gene3D-CATH	1.20.1250.20	UniProtKB/Swiss-Prot
InterPro	MFS	UniProtKB/Swiss-Prot
	MFS_dom	UniProtKB/Swiss-Prot
	MFS_trans_sf	UniProtKB/Swiss-Prot
	Proton-linked_MCT	UniProtKB/Swiss-Prot
KEGG Report	rno:309525	UniProtKB/Swiss-Prot
NCBI Gene	309525	ENTREZGENE
PANTHER	MONOCARBOXYLATE TRANSPORTER	UniProtKB/Swiss-Prot
	MONOCARBOXYLATE TRANSPORTER 12	UniProtKB/Swiss-Prot
Pfam	MFS_1	UniProtKB/Swiss-Prot
PhenoGen	Slc16a12	PhenoGen
PROSITE	MFS	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000021916	RatGTEx
Superfamily-SCOP	SSF103473	UniProtKB/Swiss-Prot
UniProt	D4A734	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-19	Slc16a12	solute carrier family 16, member 12 (monocarboxylic acid transporter 12)	Slc16a12	solute carrier family 16 (monocarboxylic acid transporters), member 12	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Slc16a12	solute carrier family 16 (monocarboxylic acid transporters), member 12	Slc16a12_predicted	solute carrier family 16 (monocarboxylic acid transporters), member 12 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Slc16a12_predicted	solute carrier family 16 (monocarboxylic acid transporters), member 12 (predicted)	RGD1311468_predicted	similar to expressed sequence AW210596 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1311468_predicted	similar to expressed sequence AW210596 (predicted)	LOC309525_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC309525_predicted	similar to expressed sequence AW210596 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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