Advanced Search (OLGA)

Gene: Ptpn3 (protein tyrosine phosphatase, non-receptor type 3) Rattus norvegicus

Analyze

Symbol:

Ptpn3

Name:

protein tyrosine phosphatase, non-receptor type 3

RGD ID:

1311363

Description:

Predicted to enable several functions, including ATPase binding activity; phosphotyrosine residue binding activity; and sodium channel regulator activity. Involved in liver regeneration. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and cytoplasmic side of plasma membrane. Orthologous to human PTPN3 (protein tyrosine phosphatase non-receptor type 3); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC362524; tyrosine-protein phosphatase non-receptor type 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	76,703,687 - 76,822,584 (-)	NCBI		GRCr8
mRatBN7.2	5	71,908,520 - 72,027,323 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	71,911,135 - 72,065,443 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	5	74,248,996 - 74,368,167 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	74,248,996 - 74,368,186 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	78,399,259 - 78,528,991 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	75,106,880 - 75,222,735 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	75,111,995 - 75,139,197 (-)	NCBI
Celera	5	70,758,167 - 70,876,826 (-)	NCBI		Celera
Cytogenetic Map	5	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptpn3	Rat	prostate cancer		ISO	RGD:1322781	8554872	ClinVar Annotator: match by term: Malignant tumor of prostate	ClinVar	PMID:23265383

Imported Disease Annotations - CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptpn3	Rat	diastolic heart failure		ISO	RGD:1322781	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:29556499

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptpn3	Rat	(-)-demecolcine	increases expression	ISO	RGD:1322781	6480464	Demecolcine results in increased expression of PTPN3 mRNA	CTD	PMID:23649840
Ptpn3	Rat	(-)-epigallocatechin 3-gallate	multiple interactions	ISO	RGD:1322781	6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PTPN3 mRNA	CTD	PMID:22079256
Ptpn3	Rat	1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene	multiple interactions	ISO	RGD:1322782	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Ptpn3	Rat	1,2-dimethylhydrazine	decreases expression	ISO	RGD:1322782	6480464	1,2-Dimethylhydrazine results in decreased expression of PTPN3 mRNA	CTD	PMID:22206623
Ptpn3	Rat	1,3-dinitrobenzene	increases expression	EXP		6480464	3-dinitrobenzene results in increased expression of PTPN3 mRNA	CTD	PMID:21983209
Ptpn3	Rat	17beta-estradiol	increases expression	ISO	RGD:1322782	6480464	Estradiol results in increased expression of PTPN3 mRNA	CTD	PMID:39298647
Ptpn3	Rat	2,2',4,4',5,5'-hexachlorobiphenyl	multiple interactions	ISO	RGD:1322782	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Ptpn3	Rat	2,2',5,5'-tetrachlorobiphenyl	multiple interactions	ISO	RGD:1322782	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Ptpn3	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	RGD:1322782	6480464	[Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased expression of PTPN3 mRNA	CTD	PMID:21212295
Ptpn3	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1322782	6480464	Tetrachlorodibenzodioxin affects the expression of PTPN3 mRNA	CTD	PMID:21570461
Ptpn3	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of PTPN3 mRNA	CTD	PMID:21215274\|PMID:33387578
Ptpn3	Rat	2,4,4'-trichlorobiphenyl	multiple interactions	ISO	RGD:1322782	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Ptpn3	Rat	2-hydroxypropanoic acid	decreases expression	ISO	RGD:1322781	6480464	Lactic Acid results in decreased expression of PTPN3 mRNA	CTD	PMID:30851411
Ptpn3	Rat	4,4'-sulfonyldiphenol	affects expression	ISO	RGD:1322782	6480464	bisphenol S affects the expression of PTPN3 mRNA	CTD	PMID:39298647
Ptpn3	Rat	4-aminobenzohydrazide	multiple interactions	ISO	RGD:1322781	6480464	4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PTPN3 mRNA]	CTD	PMID:24530881
Ptpn3	Rat	4-hydroxyphenyl retinamide	increases expression	ISO	RGD:1322782	6480464	Fenretinide results in increased expression of PTPN3 mRNA	CTD	PMID:28973697
Ptpn3	Rat	6-propyl-2-thiouracil	decreases expression	EXP		6480464	Propylthiouracil results in decreased expression of PTPN3 mRNA	CTD	PMID:24780913\|PMID:25825206
Ptpn3	Rat	acrylamide	decreases expression	EXP		6480464	Acrylamide results in decreased expression of PTPN3 mRNA	CTD	PMID:28959563
Ptpn3	Rat	aflatoxin B1	increases methylation	ISO	RGD:1322781	6480464	Aflatoxin B1 results in increased methylation of PTPN3 gene	CTD	PMID:27153756
Ptpn3	Rat	all-trans-retinoic acid	decreases expression	ISO	RGD:1322781	6480464	Tretinoin results in decreased expression of PTPN3 mRNA	CTD	PMID:16129123\|PMID:33167477
Ptpn3	Rat	all-trans-retinoic acid	increases expression	ISO	RGD:1322781	6480464	Tretinoin results in increased expression of PTPN3 mRNA	CTD	PMID:21934132
Ptpn3	Rat	all-trans-retinoic acid	affects expression	ISO	RGD:1322781	6480464	Tretinoin affects the expression of PTPN3 mRNA	CTD	PMID:15498508
Ptpn3	Rat	alpha-Zearalanol	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PTPN3 mRNA	CTD	PMID:35163327
Ptpn3	Rat	amiodarone	increases expression	ISO	RGD:1322781	6480464	Amiodarone results in increased expression of PTPN3 mRNA	CTD	PMID:19774075
Ptpn3	Rat	aristolochic acid A	decreases expression	ISO	RGD:1322781	6480464	aristolochic acid I results in decreased expression of PTPN3 mRNA	CTD	PMID:33212167
Ptpn3	Rat	arsenite(3-)	increases expression	ISO	RGD:1322782	6480464	arsenite results in increased expression of PTPN3 mRNA	CTD	PMID:33053406
Ptpn3	Rat	arsenite(3-)	decreases expression	ISO	RGD:1322782	6480464	arsenite results in decreased expression of PTPN3 protein	CTD	PMID:37955338
Ptpn3	Rat	belinostat	decreases expression	ISO	RGD:1322781	6480464	belinostat results in decreased expression of PTPN3 mRNA	CTD	PMID:27188386
Ptpn3	Rat	benzene-1,2,4-triol	decreases expression	ISO	RGD:1322781	6480464	hydroxyhydroquinone results in decreased expression of PTPN3 mRNA	CTD	PMID:24530881
Ptpn3	Rat	benzene-1,2,4-triol	multiple interactions	ISO	RGD:1322781	6480464	4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PTPN3 mRNA]	CTD	PMID:24530881
Ptpn3	Rat	benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of PTPN3 mRNA	CTD	PMID:21839799
Ptpn3	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1322781	6480464	Benzo(a)pyrene results in increased expression of PTPN3 mRNA	CTD	PMID:30453624
Ptpn3	Rat	benzo[a]pyrene	affects methylation	ISO	RGD:1322781	6480464	Benzo(a)pyrene affects the methylation of PTPN3 5' UTR	CTD	PMID:27901495
Ptpn3	Rat	benzo[a]pyrene	decreases methylation	ISO	RGD:1322782	6480464	Benzo(a)pyrene results in decreased methylation of PTPN3 exon; Benzo(a)pyrene results in decreased methylation of PTPN3 more ...	CTD	PMID:27901495
Ptpn3	Rat	beta-naphthoflavone	multiple interactions	EXP		6480464	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTPN3 mRNA	CTD	PMID:18164116
Ptpn3	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	RGD:1322781	6480464	Diethylhexyl Phthalate results in increased expression of PTPN3 mRNA	CTD	PMID:31163220
Ptpn3	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1322782	6480464	Diethylhexyl Phthalate results in decreased expression of PTPN3 mRNA	CTD	PMID:34319233
Ptpn3	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of PTPN3 mRNA	CTD	PMID:25181051\|PMID:32145629
Ptpn3	Rat	bisphenol A	decreases methylation	ISO	RGD:1322781	6480464	bisphenol A results in decreased methylation of PTPN3 gene	CTD	PMID:31601247
Ptpn3	Rat	bisphenol A	increases expression	ISO	RGD:1322782	6480464	bisphenol A results in increased expression of PTPN3 mRNA	CTD	PMID:25594700
Ptpn3	Rat	bisphenol F	increases expression	ISO	RGD:1322782	6480464	bisphenol F results in increased expression of PTPN3 mRNA	CTD	PMID:38685157
Ptpn3	Rat	butanal	decreases expression	ISO	RGD:1322781	6480464	butyraldehyde results in decreased expression of PTPN3 mRNA	CTD	PMID:26079696
Ptpn3	Rat	cadmium dichloride	decreases expression	EXP		6480464	Cadmium Chloride results in decreased expression of PTPN3 mRNA	CTD	PMID:33453195
Ptpn3	Rat	cadmium dichloride	increases expression	EXP		6480464	Cadmium Chloride results in increased expression of PTPN3 mRNA	CTD	PMID:25993096
Ptpn3	Rat	caffeine	affects phosphorylation	ISO	RGD:1322781	6480464	Caffeine affects the phosphorylation of PTPN3 protein	CTD	PMID:35688186
Ptpn3	Rat	calcitriol	decreases expression	ISO	RGD:1322781	6480464	Calcitriol results in decreased expression of PTPN3 mRNA	CTD	PMID:16129123
Ptpn3	Rat	calcitriol	increases expression	ISO	RGD:1322781	6480464	Calcitriol results in increased expression of PTPN3 mRNA	CTD	PMID:26485663
Ptpn3	Rat	calyculin A	decreases expression	ISO	RGD:1322782	6480464	calyculin A results in decreased expression of PTPN3 mRNA	CTD	PMID:25270620
Ptpn3	Rat	cannabidiol	decreases methylation	ISO	RGD:1322782	6480464	Cannabidiol results in decreased methylation of PTPN3 gene	CTD	PMID:32579259
Ptpn3	Rat	carmustine	decreases expression	ISO	RGD:1322781	6480464	Carmustine results in decreased expression of PTPN3 mRNA	CTD	PMID:15980968
Ptpn3	Rat	CGP 52608	multiple interactions	ISO	RGD:1322781	6480464	CGP 52608 promotes the reaction [RORA protein binds to PTPN3 gene]	CTD	PMID:28238834
Ptpn3	Rat	choline	multiple interactions	ISO	RGD:1322782	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression more ...	CTD	PMID:20938992
Ptpn3	Rat	cisplatin	increases expression	ISO	RGD:1322781	6480464	Cisplatin results in increased expression of PTPN3 mRNA	CTD	PMID:27392435
Ptpn3	Rat	cisplatin	multiple interactions	ISO	RGD:1322781	6480464	[Cisplatin co-treated with jinfukang] results in increased expression of PTPN3 mRNA	CTD	PMID:27392435
Ptpn3	Rat	clofibrate	decreases expression	ISO	RGD:1322782	6480464	Clofibrate results in decreased expression of PTPN3 mRNA	CTD	PMID:25270620
Ptpn3	Rat	clothianidin	increases expression	ISO	RGD:1322781	6480464	clothianidin results in increased expression of PTPN3 mRNA	CTD	PMID:29044138
Ptpn3	Rat	cocaine	affects expression	EXP		6480464	Cocaine affects the expression of PTPN3 mRNA	CTD	PMID:20187946
Ptpn3	Rat	copper atom	multiple interactions	ISO	RGD:1322781	6480464	[NSC 689534 binds to Copper] which results in decreased expression of PTPN3 mRNA	CTD	PMID:20971185
Ptpn3	Rat	copper(0)	multiple interactions	ISO	RGD:1322781	6480464	[NSC 689534 binds to Copper] which results in decreased expression of PTPN3 mRNA	CTD	PMID:20971185
Ptpn3	Rat	copper(II) sulfate	decreases expression	ISO	RGD:1322781	6480464	Copper Sulfate results in decreased expression of PTPN3 mRNA	CTD	PMID:19549813
Ptpn3	Rat	corticosterone	decreases expression	EXP		6480464	Corticosterone results in decreased expression of PTPN3 mRNA	CTD	PMID:15755911
Ptpn3	Rat	coumarin	decreases phosphorylation	ISO	RGD:1322781	6480464	coumarin results in decreased phosphorylation of PTPN3 protein	CTD	PMID:35688186
Ptpn3	Rat	crotonaldehyde	decreases expression	ISO	RGD:1322781	6480464	2-butenal results in decreased expression of PTPN3 mRNA	CTD	PMID:20471460
Ptpn3	Rat	cyclosporin A	increases expression	ISO	RGD:1322781	6480464	Cyclosporine results in increased expression of PTPN3 mRNA	CTD	PMID:25562108
Ptpn3	Rat	cyclosporin A	increases methylation	ISO	RGD:1322781	6480464	Cyclosporine results in increased methylation of PTPN3 promoter	CTD	PMID:27989131
Ptpn3	Rat	dioxygen	multiple interactions	EXP		6480464	[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression more ...	CTD	PMID:33729688
Ptpn3	Rat	dorsomorphin	multiple interactions	ISO	RGD:1322781	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Ptpn3	Rat	doxorubicin	decreases expression	ISO	RGD:1322781	6480464	Doxorubicin results in decreased expression of PTPN3 mRNA	CTD	PMID:29803840
Ptpn3	Rat	endosulfan	increases expression	EXP		6480464	Endosulfan results in increased expression of PTPN3 mRNA	CTD	PMID:29391264
Ptpn3	Rat	entinostat	increases expression	ISO	RGD:1322781	6480464	entinostat results in increased expression of PTPN3 mRNA	CTD	PMID:27188386
Ptpn3	Rat	ethanol	increases expression	ISO	RGD:1322781	6480464	Ethanol results in increased expression of PTPN3 mRNA	CTD	PMID:28986285
Ptpn3	Rat	finasteride	increases expression	EXP		6480464	Finasteride results in increased expression of PTPN3 mRNA	CTD	PMID:24136188
Ptpn3	Rat	folic acid	multiple interactions	ISO	RGD:1322782	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression more ...	CTD	PMID:20938992
Ptpn3	Rat	FR900359	affects phosphorylation	ISO	RGD:1322781	6480464	FR900359 affects the phosphorylation of PTPN3 protein	CTD	PMID:37730182
Ptpn3	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of PTPN3 mRNA	CTD	PMID:33387578
Ptpn3	Rat	glafenine	increases expression	EXP		6480464	Glafenine results in increased expression of PTPN3 mRNA	CTD	PMID:24136188
Ptpn3	Rat	glyphosate	affects methylation	EXP		6480464	Glyphosate affects the methylation of PTPN3 gene	CTD	PMID:35440735
Ptpn3	Rat	indometacin	decreases expression	EXP		6480464	Indomethacin results in decreased expression of PTPN3 mRNA	CTD	PMID:25972201
Ptpn3	Rat	ivermectin	decreases expression	ISO	RGD:1322781	6480464	Ivermectin results in decreased expression of PTPN3 protein	CTD	PMID:32959892
Ptpn3	Rat	L-methionine	multiple interactions	ISO	RGD:1322782	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression more ...	CTD	PMID:20938992
Ptpn3	Rat	lapatinib	multiple interactions	ISO	RGD:1322781	6480464	lapatinib inhibits the reaction [EGFR protein binds to PTPN3 protein]; lapatinib promotes the reaction [pirfenidone more ...	CTD	PMID:28739874
Ptpn3	Rat	lipopolysaccharide	decreases expression	ISO	RGD:1322782	6480464	Lipopolysaccharides results in decreased expression of PTPN3 mRNA	CTD	PMID:21212295
Ptpn3	Rat	lipopolysaccharide	multiple interactions	ISO	RGD:1322782	6480464	[Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased expression of PTPN3 mRNA	CTD	PMID:21212295
Ptpn3	Rat	methapyrilene	decreases expression	EXP		6480464	Methapyrilene results in decreased expression of PTPN3 mRNA	CTD	PMID:30467583
Ptpn3	Rat	methyl methanesulfonate	decreases expression	ISO	RGD:1322781	6480464	Methyl Methanesulfonate results in decreased expression of PTPN3 mRNA	CTD	PMID:23649840
Ptpn3	Rat	methylmercury chloride	increases expression	ISO	RGD:1322781	6480464	methylmercuric chloride results in increased expression of PTPN3 mRNA	CTD	PMID:28001369
Ptpn3	Rat	N(6)-dimethylallyladenine	decreases expression	ISO	RGD:1322781	6480464	N(6)-(delta(2)-isopentenyl)adenine results in decreased expression of PTPN3 mRNA	CTD	PMID:16129123
Ptpn3	Rat	N-nitrosodiethylamine	multiple interactions	EXP		6480464	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTPN3 mRNA	CTD	PMID:18164116
Ptpn3	Rat	paracetamol	decreases expression	ISO	RGD:1322781	6480464	Acetaminophen results in decreased expression of PTPN3 mRNA	CTD	PMID:21420995\|PMID:29067470
Ptpn3	Rat	paracetamol	increases expression	ISO	RGD:1322781	6480464	Acetaminophen results in increased expression of PTPN3 mRNA	CTD	PMID:22230336
Ptpn3	Rat	PCB138	multiple interactions	ISO	RGD:1322782	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Ptpn3	Rat	perfluorooctanoic acid	multiple interactions	EXP		6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of PTPN3 mRNA	CTD	PMID:35163327
Ptpn3	Rat	phenformin	increases expression	EXP		6480464	Phenformin results in increased expression of PTPN3 mRNA	CTD	PMID:31324951
Ptpn3	Rat	phenobarbital	decreases expression	ISO	RGD:1322782	6480464	Phenobarbital results in decreased expression of PTPN3 mRNA	CTD	PMID:25270620
Ptpn3	Rat	pirfenidone	multiple interactions	ISO	RGD:1322781	6480464	[pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]] which results in decreased phosphorylation more ...	CTD	PMID:28739874
Ptpn3	Rat	potassium chromate	decreases expression	ISO	RGD:1322781	6480464	potassium chromate(VI) results in decreased expression of PTPN3 mRNA	CTD	PMID:22079256
Ptpn3	Rat	potassium chromate	multiple interactions	ISO	RGD:1322781	6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of PTPN3 mRNA	CTD	PMID:22079256
Ptpn3	Rat	rac-lactic acid	decreases expression	ISO	RGD:1322781	6480464	Lactic Acid results in decreased expression of PTPN3 mRNA	CTD	PMID:30851411
Ptpn3	Rat	rotenone	decreases expression	ISO	RGD:1322781	6480464	Rotenone results in decreased expression of PTPN3 mRNA	CTD	PMID:29955902
Ptpn3	Rat	rotenone	increases expression	EXP		6480464	Rotenone results in increased expression of PTPN3 mRNA	CTD	PMID:28374803
Ptpn3	Rat	SB 431542	multiple interactions	ISO	RGD:1322781	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Ptpn3	Rat	sunitinib	decreases expression	ISO	RGD:1322781	6480464	Sunitinib results in decreased expression of PTPN3 mRNA	CTD	PMID:31533062
Ptpn3	Rat	tamibarotene	affects expression	ISO	RGD:1322781	6480464	tamibarotene affects the expression of PTPN3 mRNA	CTD	PMID:15498508
Ptpn3	Rat	temozolomide	decreases expression	ISO	RGD:1322781	6480464	Temozolomide results in decreased expression of PTPN3 mRNA	CTD	PMID:31758290
Ptpn3	Rat	tetrachloromethane	decreases expression	ISO	RGD:1322782	6480464	Carbon Tetrachloride results in decreased expression of PTPN3 mRNA	CTD	PMID:31919559
Ptpn3	Rat	thiram	decreases expression	ISO	RGD:1322781	6480464	Thiram results in decreased expression of PTPN3 mRNA	CTD	PMID:38568856
Ptpn3	Rat	titanium dioxide	increases expression	ISO	RGD:1322782	6480464	titanium dioxide results in increased expression of PTPN3 mRNA	CTD	PMID:35295148
Ptpn3	Rat	titanium dioxide	increases methylation	ISO	RGD:1322782	6480464	titanium dioxide results in increased methylation of PTPN3 gene	CTD	PMID:35295148
Ptpn3	Rat	toluene	increases expression	EXP		6480464	Toluene results in increased expression of PTPN3 mRNA	CTD	PMID:22967744
Ptpn3	Rat	triclosan	increases expression	ISO	RGD:1322781	6480464	Triclosan results in increased expression of PTPN3 mRNA	CTD	PMID:30510588
Ptpn3	Rat	triphenyl phosphate	increases expression	EXP		6480464	triphenyl phosphate results in increased expression of PTPN3 mRNA	CTD	PMID:30589522
Ptpn3	Rat	valproic acid	decreases methylation	ISO	RGD:1322781	6480464	Valproic Acid results in decreased methylation of PTPN3 gene	CTD	PMID:29154799
Ptpn3	Rat	valproic acid	affects expression	ISO	RGD:1322781	6480464	Valproic Acid affects the expression of PTPN3 mRNA	CTD	PMID:25979313
Ptpn3	Rat	valproic acid	increases expression	ISO	RGD:1322781	6480464	Valproic Acid results in increased expression of PTPN3 mRNA	CTD	PMID:19101580\|PMID:23179753\|PMID:24935251\|PMID:26272509\|PMID:28001369
Ptpn3	Rat	valproic acid	multiple interactions	ISO	RGD:1322781	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Ptpn3	Rat	vincristine	increases expression	ISO	RGD:1322781	6480464	Vincristine results in increased expression of PTPN3 mRNA	CTD	PMID:23649840

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptpn3	Rat	liver regeneration		IEP		1599982		RGD
Ptpn3	Rat	negative regulation of membrane protein ectodomain proteolysis	involved_in	ISO	RGD:1322781	1624291	PMID:12207026	RGD	PMID:12207026
Ptpn3	Rat	negative regulation of mitotic cell cycle	involved_in	ISO	RGD:1322781	1624291	PMID:10364224	RGD	PMID:10364224
Ptpn3	Rat	regulation of membrane depolarization during action potential	involved_in	ISO	RGD:1322781	1624291	PMID:16930557	RGD	PMID:16930557
Ptpn3	Rat	regulation of sodium ion transmembrane transport	involved_in	ISO	RGD:1322781	1624291	PMID:16930557	RGD	PMID:16930557

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptpn3	Rat	cytoplasm	located_in	ISO	RGD:1322781	1624291	PMID:10940933	RGD	PMID:10940933
Ptpn3	Rat	cytoplasm	is_active_in	IBA	PANTHER:PTN001057123\|UniProtKB:P26045\|UniProtKB:P29074	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ptpn3	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ptpn3	Rat	cytoplasmic side of plasma membrane	located_in	ISO	RGD:1322781	1624291	PMID:10940933	RGD	PMID:10940933
Ptpn3	Rat	cytoplasmic side of plasma membrane	is_active_in	IBA	PANTHER:PTN001057123\|UniProtKB:P26045\|UniProtKB:P29074	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ptpn3	Rat	cytoskeleton	located_in	IEA	UniProtKB-SubCell:SL-0090	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Ptpn3	Rat	cytoskeleton	located_in	IEA	InterPro:IPR000299	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Ptpn3	Rat	cytoskeleton	located_in	IEA	UniProtKB-KW:KW-0206	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ptpn3	Rat	ATPase binding	enables	ISO	RGD:1322781	1624291	UniProtKB:P55072 PMID:10364224	RGD	PMID:10364224
Ptpn3	Rat	cytoskeletal protein binding	enables	IEA	InterPro:IPR012151	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Ptpn3	Rat	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ptpn3	Rat	phosphoprotein phosphatase activity	enables	IEA	UniProtKB-KW:KW-0904	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ptpn3	Rat	phosphotyrosine residue binding	enables	ISO	RGD:1322781	1624291	UniProtKB:P55072 PMID:10364224	RGD	PMID:10364224
Ptpn3	Rat	protein binding	enables	ISO	RGD:1322781	1624291	UniProtKB:P06463\|UniProtKB:P10912\|UniProtKB:P11473\|UniProtKB:P23508\|UniProtKB:P25800\|UniProtKB:P31040\|UniProtKB:P31946\|UniProtKB:P40692\|UniProtKB:P42566-1\|UniProtKB:P55072\|UniProtKB:P61981\|UniProtKB:P63104\|UniProtKB:P78536\|UniProtKB:Q01664\|UniProtKB:Q04828\|UniProtKB:Q14524\|UniProtKB:Q14689-6\|UniProtKB:Q5GFL6-3\|UniProtKB:Q6ZRS2-3\|UniProtKB:Q8NEK8\|UniProtKB:Q8TAA9\|UniProtKB:Q8TBK6\|UniProtKB:Q8WV44\|UniProtKB:Q96QG7\|UniProtKB:Q9H8W4\|UniProtKB:Q9NNW5\|UniProtKB:Q9NPJ8\|UniProtKB:Q9ULK5 PMID:10364224, PMID:12207026, PMID:12907755, PMID:15161933, PMID:16930557, PMID:17947517, PMID:20936779, PMID:21119599, PMID:25416956, PMID:25728925, PMID:27880917, PMID:28330616, PMID:28514442, more ...	RGD	PMID:10364224\|PMID:12207026\|PMID:12907755\|PMID:15161933\|PMID:16930557\|PMID:17947517\|PMID:20936779\|PMID:21119599\|PMID:25416956\|PMID:25728925\|PMID:27880917\|PMID:28330616\|PMID:28514442\|PMID:32296183\|PMID:33961781\|PMID:35271311\|PMID:36931259\|PMID:9341175
Ptpn3	Rat	protein tyrosine phosphatase activity	enables	ISO	RGD:1322781	1624291	PMID:10364224, PMID:19167335	RGD	PMID:10364224\|PMID:19167335
Ptpn3	Rat	protein tyrosine phosphatase activity	enables	IEA	EC:3.1.3.48	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Ptpn3	Rat	protein tyrosine phosphatase activity	enables	IEA	InterPro:IPR000242\|InterPro:IPR012151	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Ptpn3	Rat	protein tyrosine phosphatase activity	enables	IBA	FB:FBgn0261985\|MGI:1099792\|PANTHER:PTN005236628\|RGD:620216\|UniProtKB:P26045\|UniProtKB:Q15678	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ptpn3	Rat	sodium channel regulator activity	enables	ISO	RGD:1322781	1624291	PMID:16930557	RGD	PMID:16930557

Disease Annotations Click to see Annotation Detail View

diastolic heart failure (ISO)

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

4-aminobenzohydrazide (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

amiodarone (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

belinostat (ISO)

benzene-1,2,4-triol (ISO)

benzo[a]pyrene (EXP,ISO)

beta-naphthoflavone (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

calcitriol (ISO)

calyculin A (ISO)

cannabidiol (ISO)

carmustine (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

clofibrate (ISO)

clothianidin (ISO)

cocaine (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

corticosterone (EXP)

coumarin (ISO)

crotonaldehyde (ISO)

cyclosporin A (ISO)

dioxygen (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethanol (ISO)

finasteride (EXP)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

glafenine (EXP)

glyphosate (EXP)

indometacin (EXP)

ivermectin (ISO)

L-methionine (ISO)

lapatinib (ISO)

lipopolysaccharide (ISO)

methapyrilene (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N(6)-dimethylallyladenine (ISO)

N-nitrosodiethylamine (EXP)

paracetamol (ISO)

PCB138 (ISO)

perfluorooctanoic acid (EXP)

phenformin (EXP)

phenobarbital (ISO)

pirfenidone (ISO)

potassium chromate (ISO)

rac-lactic acid (ISO)

rotenone (EXP,ISO)

SB 431542 (ISO)

sunitinib (ISO)

tamibarotene (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thiram (ISO)

titanium dioxide (ISO)

toluene (EXP)

triclosan (ISO)

triphenyl phosphate (EXP)

valproic acid (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

liver regeneration (IEP)

negative regulation of membrane protein ectodomain proteolysis (ISO)

negative regulation of mitotic cell cycle (ISO)

regulation of membrane depolarization during action potential (ISO)

regulation of sodium ion transmembrane transport (ISO)

Cellular Component

cytoplasm (IBA,IEA,ISO)

cytoplasmic side of plasma membrane (IBA,ISO)

cytoskeleton (IEA)

Molecular Function

ATPase binding (ISO)

cytoskeletal protein binding (IEA)

hydrolase activity (IEA)

phosphoprotein phosphatase activity (IEA)

phosphotyrosine residue binding (ISO)

protein binding (ISO)

protein tyrosine phosphatase activity (IBA,IEA,ISO)

sodium channel regulator activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Gene expressions of protein tyrosine phosphatases in regenerating rat liver and rat ascites hepatoma cells.	Kitamura T, etal., Jpn J Cancer Res. 1995 Sep;86(9):811-8.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation
9.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:10364224	PMID:10940933	PMID:12207026	PMID:16930557	PMID:19167335

Genomics

Comparative Map Data

Ptpn3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	76,703,687 - 76,822,584 (-)	NCBI		GRCr8
mRatBN7.2	5	71,908,520 - 72,027,323 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	71,911,135 - 72,065,443 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	5	74,248,996 - 74,368,167 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	74,248,996 - 74,368,186 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	78,399,259 - 78,528,991 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	75,106,880 - 75,222,735 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	75,111,995 - 75,139,197 (-)	NCBI
Celera	5	70,758,167 - 70,876,826 (-)	NCBI		Celera
Cytogenetic Map	5	q24	NCBI

PTPN3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	109,375,694 - 109,538,420 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	109,375,466 - 109,498,313 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	112,137,974 - 112,260,587 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	111,180,337 - 111,265,557 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	109,220,072 - 109,305,289	NCBI
Celera	9	82,637,279 - 82,759,899 (-)	NCBI		Celera
Cytogenetic Map	9	q31.3	NCBI
HuRef	9	81,738,137 - 81,860,645 (-)	NCBI		HuRef
CHM1_1	9	112,284,708 - 112,407,241 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	121,545,088 - 121,707,765 (-)	NCBI		T2T-CHM13v2.0

Ptpn3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	57,190,841 - 57,339,036 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	57,190,841 - 57,301,837 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	57,190,841 - 57,339,040 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	57,190,841 - 57,301,837 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	57,203,713 - 57,314,709 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	57,284,895 - 57,394,944 (-)	NCBI		MGSCv36	mm8
Celera	4	57,101,096 - 57,212,390 (-)	NCBI		Celera
Cytogenetic Map	4	B3	NCBI
cM Map	4	31.66	NCBI

Ptpn3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	17,493,518 - 17,645,477 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	17,560,664 - 17,645,420 (+)	NCBI	ChiLan1.0	ChiLan1.0

PTPN3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	29,908,994 - 30,031,769 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	29,911,359 - 30,031,626 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	80,528,896 - 80,651,629 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	108,699,761 - 108,787,464 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	108,699,761 - 108,787,464 (-)	Ensembl	panpan1.1		panPan2

PTPN3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	64,486,293 - 64,595,416 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	64,489,446 - 64,630,004 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	62,886,334 - 63,029,951 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	65,619,500 - 65,763,908 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	65,619,501 - 65,764,431 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	64,139,495 - 64,283,404 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	64,160,914 - 64,305,281 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	64,851,489 - 64,995,173 (-)	NCBI		UU_Cfam_GSD_1.0

Ptpn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	179,719,264 - 179,830,375 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936559	3,436,651 - 3,547,275 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936559	3,436,114 - 3,547,316 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTPN3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	250,418,133 - 250,540,480 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	250,418,131 - 250,583,148 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PTPN3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	30,048,941 - 30,168,816 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	30,083,128 - 30,171,473 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666035	12,548,993 - 12,668,966 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ptpn3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	2,011,732 - 2,170,348 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	2,011,998 - 2,170,096 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ptpn3
573 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	559
Count of miRNA genes:	254
Interacting mature miRNAs:	298
Transcripts:	ENSRNOT00000059627
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578776	Stresp18	Stress response QTL 18	2.9		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	5	27955440	72955440	Rat
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	33215665	78215665	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	47869062	90099692	Rat
1357396	Bw44	Body weight QTL 44	4.19		body mass (VT:0001259)	body weight (CMO:0000012)	5	68984307	104251008	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
61380	Edpm5	Estrogen-dependent pituitary mass QTL 5	4.5	0.92	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	5	68984307	104251008	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	18873947	74251464	Rat
634305	Mamtr1	Mammary tumor resistance QTL 1		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	12789751	113558310	Rat
61386	Bp49	Blood pressure QTL 49	16.6		cerebrum integrity trait (VT:0010549)	brain infarction volume (CMO:0001013)	5	60293434	98603051	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	43726656	129132602	Rat
1357402	Bw46	Body weight QTL 46	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	68984307	104251008	Rat
2302381	Bw84	Body weight QTL 84	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	68984307	104251008	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	33215665	78215665	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	33215665	78215665	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
6903292	Stl28	Serum triglyceride level QTL 28	2.6	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	5	28515489	73515489	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1578767	Stresp17	Stress response QTL 17	4.3	0.01	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	5	27955440	72955440	Rat
7411561	Bw134	Body weight QTL 134	24	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	49463600	94463600	Rat
2303615	Vencon7	Ventilatory control QTL 7		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	5	50983895	95983895	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
6903306	Scl35	Serum cholesterol QTL 35	2.6	0.0073	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	28515489	73515489	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	34730116	104251008	Rat
7394712	Emca13	Estrogen-induced mammary cancer QTL 13			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	9823266	99753708	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	43726656	86724018	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55805606	132207589	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	729470	86724018	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	55715622	100715622	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	31663789	131345958	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
9589025	Epfw7	Epididymal fat weight QTL 7	20.66	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	5	49463600	94463600	Rat
2303574	Gluco42	Glucose level QTL 42	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	53496719	98496719	Rat
2290005	Mcs24	Mammary carcinoma susceptibility QTL 24			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	64719390	109719390	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	1	90450412	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	66174080	124160948	Rat
2316954	Rf57	Renal function QTL 57	0		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	59793528	90450144	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	58829236	128034027	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	34944474	113558310	Rat
2312671	Scl64	Serum cholesterol level QTL 64		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	68984307	104251008	Rat
2316957	Pur21	Proteinuria QTL 21	6.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	5	59793528	113558156	Rat

Markers in Region

D5Mit17

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	71,963,533 - 71,963,668 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	74,304,359 - 74,304,493	NCBI	Rnor6.0
Rnor_5.0	5	78,454,425 - 78,454,559	UniSTS	Rnor5.0
RGSC_v3.4	5	75,159,412 - 75,159,546	UniSTS	RGSC3.4
RGSC_v3.4	5	75,159,411 - 75,159,546	RGD	RGSC3.4
RGSC_v3.1	5	75,164,525 - 75,164,659	RGD
Celera	5	70,813,108 - 70,813,242	UniSTS
RH 3.4 Map	5	487.8	UniSTS
RH 3.4 Map	5	487.8	RGD
RH 2.0 Map	5	371.2	RGD
Cytogenetic Map	5	q24	UniSTS

D5Rat182

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	71,963,532 - 71,963,722 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	74,304,358 - 74,304,547	NCBI	Rnor6.0
Rnor_5.0	5	78,454,424 - 78,454,613	UniSTS	Rnor5.0
RGSC_v3.4	5	75,159,410 - 75,159,600	RGD	RGSC3.4
RGSC_v3.4	5	75,159,411 - 75,159,600	UniSTS	RGSC3.4
RGSC_v3.1	5	75,164,413 - 75,164,721	RGD
Celera	5	70,813,107 - 70,813,296	UniSTS
FHH x ACI Map	5	36.89	RGD
FHH x ACI Map	5	36.89	UniSTS
Cytogenetic Map	5	q24	UniSTS

RH141861

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	71,908,518 - 71,908,725 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	74,248,995 - 74,249,201	NCBI	Rnor6.0
Rnor_5.0	5	78,399,258 - 78,399,464	UniSTS	Rnor5.0
RGSC_v3.4	5	75,104,609 - 75,104,815	UniSTS	RGSC3.4
Celera	5	70,758,166 - 70,758,372	UniSTS
RH 3.4 Map	5	483.5	UniSTS
Cytogenetic Map	5	q24	UniSTS

RH132655

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	71,960,402 - 71,960,593 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	74,301,229 - 74,301,419	NCBI	Rnor6.0
Rnor_5.0	5	78,451,295 - 78,451,485	UniSTS	Rnor5.0
RGSC_v3.4	5	75,156,347 - 75,156,537	UniSTS	RGSC3.4
Celera	5	70,810,035 - 70,810,225	UniSTS
RH 3.4 Map	5	484.6	UniSTS
Cytogenetic Map	5	q24	UniSTS

AI555271

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	71,911,367 - 71,911,552 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	74,251,844 - 74,252,028	NCBI	Rnor6.0
Rnor_5.0	5	78,402,107 - 78,402,291	UniSTS	Rnor5.0
RGSC_v3.4	5	75,107,458 - 75,107,642	UniSTS	RGSC3.4
Celera	5	70,761,015 - 70,761,199	UniSTS
RH 3.4 Map	5	486.1	UniSTS
Cytogenetic Map	5	q24	UniSTS

AU049242

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	71,963,570 - 71,963,711 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	74,304,396 - 74,304,536	NCBI	Rnor6.0
Rnor_5.0	5	78,454,462 - 78,454,602	UniSTS	Rnor5.0
RGSC_v3.4	5	75,159,449 - 75,159,589	UniSTS	RGSC3.4
Celera	5	70,813,145 - 70,813,285	UniSTS
Cytogenetic Map	5	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001055793	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001059757	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006225308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763739	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775961	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017603009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC092605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC103629	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000059627 ⟹ ENSRNOP00000056382

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	71,911,135 - 72,026,586 (-)	Ensembl
Rnor_6.0 Ensembl	5	74,250,453 - 74,368,186 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076106 ⟹ ENSRNOP00000068051

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	71,911,135 - 72,026,586 (-)	Ensembl
Rnor_6.0 Ensembl	5	74,248,996 - 74,367,267 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076705 ⟹ ENSRNOP00000068252

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	71,911,135 - 72,026,492 (-)	Ensembl
Rnor_6.0 Ensembl	5	74,252,602 - 74,366,817 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096667 ⟹ ENSRNOP00000081216

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	71,911,135 - 72,065,443 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104839 ⟹ ENSRNOP00000077016

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	71,911,135 - 72,025,696 (-)	Ensembl

RefSeq Acc Id:

NM_001100754 ⟹ NP_001094224

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	76,703,687 - 76,821,221 (-)	NCBI

RefSeq Acc Id:

XM_001059757 ⟹ XP_001059757

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	76,703,687 - 76,821,763 (-)	NCBI
mRatBN7.2	5	71,908,520 - 72,026,608 (-)	NCBI
Rnor_6.0	5	74,248,996 - 74,367,571 (-)	NCBI
Rnor_5.0	5	78,399,259 - 78,528,991 (-)	NCBI
RGSC_v3.4	5	75,106,880 - 75,222,735 (-)	RGD

Sequence:

show sequence

TGAATGGATGAGTGATACTGTTTAGAAGGCGATAAAGGACTTGGAGAGGAGCAAGAGGTCAGGG
CTAATTTAGAAAGGTAGCTGGAAAGGTACGAAAGGTACCTGAACGATTAGAGGGCGCAGGGCAC
CAGCAAAGCAGAGGAAAAGGCGTCCTACCCGGAGGGAAAGGCAGTGTAAACGTCTCGAGGCGGG
TCAAGTTCAGAGGGTGTGATGGGGAGGAAGGTGCAGTCTGAGCGCAGGAAGGCAGGTGTGGGAG
GAGGCGGAAGAGGCCGGCTGGAACGCCGGCCACTAGGGGCCCTGAAGGCTTTGGGAAGGGCTAA
CCTTCCTGGCGTCCTAGGGCCAGCAAAGGAGCCCCGCGACTCCCAACTCAGCCACGGAGCCGCT
GGAGTCGGCGCAACCCCCAACTCAGCCACGGAACCACCGAGCAAGGCTCGCTGTCATTTCAGAT
TCGTTGTGCGCCAAGCTCTTGCCATTCCTAGGCATGCAATCCCGGAAAGCCAAGCACACAGTTA
CTCGGCGGCCGTTATGACCTCCCGGTTACGTGCGTTGGGTGGAAGAATTAATAATATACGGACC
TCAGAATTGCCCAAAGAGAAAACTCGATCCGAGGTCACCTGCAGCATACGCTTTTTAGATGGCT
TGGTACAGACCTTTAAAGTTAATAAACAAGATTTGGGCCAGTCACTTCTGGATATGGCCTATGG
CCACCTGGGCGTGACGGAGAAGGAATACTTCGGCTTGCAACATGGCGATGACCCAGTGGACTCC
CCCAGATGGCTCGAGGCAAGCAAACCCCTCAGGAAGCAGCTGAAAGGAGGTCTCCCCTGTATCC
TGCATTTTCGAGTAAGATATTTTATACCTGACCCCAACACGCTGCAGCAGGAACAAACCAGGCA
TTTGTATTTCTTACAACTGAAGATGGATGTTTGTGAAGGAAGGTTAACCTGCCCTCTCAACTCA
GCGGTGGTTCTAGCATCCTATGCAGTGCAATCTCATATCGGAGACTTTAATTCTTCCATACATC
ATCCAGGCTATCTTGCCGACAGCCAGTTCATACCAGATCAAAATGATGACTTTCTAAGCAAGGT
GGAGTCACTCCACGAACAGCACAGTGGGCTAAAGCAGTCAGAAGCCGAATCTTGCTACATCAAC
ATAGCTCGAACCCTTGACTTCTACGGAGTGGAGCTTCATGGAGGCAGAGATCTACACAATTTAG
ATCTAATGATCGGAATTGCGTCTGCAGGCATCGCAGTGTACCGAAAATACATCTGCACAAGTTT
CTACCCTTGGGTGAACATACTCAAAATTTCTTTCAAAAGGAAAAAGTTCTTCATACACCAGCGG
CAAAAGCAGGCTGAATCCAGGGAACATATCGTGGCCTTCAACATGCTGAATTACCGATCCTGCA
AGAACTTGTGGAAATCCTGCGTGGAGCACCATTCGTTCTTTCAGGCAAAAAAGTTACTACCTCA
GGAAAAGAATGTTCTGTCTCAGTACTGGACTCTAGGCTCCAGGAACCCCAAAAAGTCTGTAAAT
AACCAATATTGCAAAAAGGTGATTGGAGGGATGGTGTGGAACCCAGTCATGAGGAGATCCTTAT
CGGTGGAACGGCTAGAAACCAAGAGTCTGCCTTCCCGGTCGCCTCCCATCACCCCCAACTGGCG
AAGTCCACGGCTCCGCCATGAAATCCGCAAGCCCCGCCATTCCTCCGCAGACAACCTGGCCAAT
GAGATGACCTACATCACAGAAACGGAGGACGTGTTCTATACCTACAAGGGATCCCTATCCCCCA
AAGACAGCGATTCCGAAGTTTCCCAGAACCACAGCCCACACCGGGGGAGTCTGTCTGAAAACAA
CCCAGCCCAAAGCTGCCTGACCCAGAAGTCATCCAGTTCTGTGTCTCCATGTTCAAATGCACCA
GGCTCCTTCTCCCCAGATGGAGTTGACCAGCAGTTCTTAGAAGACTACCACAAGGTGACCAAAG
GAGGCTCCATCGAGGAAGCCAGCCAGTACTACTGTGATAAGAATGACGATGGCGATGGCTACCT
AGTCCTGATCCGGATCACACCAGATAAAGAGGGAAGATTTGGATTTAATCTTAAGGGAGGAGTG
GATCAAAAGATGCCGCTTGTGGTCTCGAGGATCAACCCAGAGTCCCCTGCGGATACCTGCATGC
CGAAACTGAATGAAGGGGATCAGATCGTGCTGATCAATGGCCGGGACATCTCAGAGCACACTCA
CGACCAGGTGGTGATGTTCATCAAAGCAAGCCGGGAGTCCCACTCGAGAGAATTGGCCCTGGTG
ATCAGGAGGAAAGCTGTACGCTCGCTGGCGGAGATCAGATCGGAAGATGAGCTGAGTCAGCTTT
TCCCAGAAGCCATGTTTCCTGCGTGTCCTGAGGGTGGGGACAGTCTGGAGGGATCCATGGAGCT
GTTAAAGAAAGGTCTGGAAAGCGGTACAGTGTTGATCCAGTTTGAGCAACTCTACAGAAAGAAG
CCCGGCTTGGCCGTCACATTTGCAAAGCTGCCTCAAAATTTGGATAAAAACCGATACAAAGATG
TGTTGCCTTACGACACCACCCGGGTATTATTGCAGGGAAATGAAGATTATATTAATGCCAGTTA
TGTGAACATGGAGATTCCCGCTGCTAACCTTGTGAACAAGTACATTGCCACTCAGGGACCGCTG
CCACACACCTGTGCACAGTTTTGGCAAGTTGTCTGGGATCAGAAGTTGTCTCTTGTTGTCATGC
TGACAACTCTCACAGAGCGAGGGCGGACCAAATGTCACCAGTACTGGCCAGATCCCCCTGACAT
CATGGACCACGGCATCTTTCACATCCAGTGTCAGGCAGAGGACTGTACCATTGCTTACGTGTCC
CGAGAAATGCTTGTTACAAACACTGAGACCGGGGAAGAGCACACAGTGACCCATCTCCAATATG
TCGCGTGGCCTGACCACGGCGTGCCTGATGACTCCTCAGACTTCCTGGAGTTTGTGAAGTACGT
GAGGTCCCTGCGGGTAGGCGGTGAGCCTGCCCTTGTTCACTGCAGTGCGGGAATAGGTCGAACA
GGTGTATTGGTCACTATGGAAACAGCCATGTGCTTAATTGAGAGGAACCTGCCTGTTTACCCAC
TGGATATTGTCCGGAAAATGAGAGACCAGCGCGCCATGATGGTGCAGACATCAAGCCAATACAA
GTTTGTGTGTGAAGCGATTCTTCGAGTGTATGAAGAAGGCTTAGTCCAGACGTTGGATCCCAGT
TAGGACAACTGTGAAGTGGTCATTCCTCCTTCCCTAGGGCGACTTCCTGAACAAGGGGACGCAC
ATTCCCCTGGAGGCCTCCAGAGATGCTGGTCACTGTGGGAAAGGGATGAGCTTCTCCGAACCCA
GGCACTTTAAATTTCTGTGGAAAAGATATCCTGTACATAAGAACTGATATGTAGATGTGCATGC
AGCTATGACTCCTTTGGGCCCAGAGATAAGCAACAGGGGATCTCCAGTTGGGAACTGTGTTTCT
CCCTACATATCACCGTCCCCCGTCATCCATCCTTGAGCAGTGAAAGGGGACACCAGCAGTGCTG
TTGACACCCCTCCCACCAGAAGCCAGACAACGTGGCTGCTTGTGGTTGCTCAAGTGTTTTGTGT
GTTGTTCTGTGTGGGACTCCAAGGGCTGAACTTGCTTGGCAATTGGTGTCCATTACCCCTGACA
CCAGGGAAAACTCAGATGAATGTAACACAGGCAGGGCACAAGGGACTTCAGGCCGGAGGATAAA
CAGGATCTATTCTGCCCTCCCTCCCTCCTTCTGCCTCATCTCTACCCCTTCTGCCACCCAAAGC
ACCCCGTTTCCCCACCCCGAATTCCTTCTCTTCAGGATCACGCCCAGTGCCTGAACCAGTCTCA
TGATGTATGTTCAGGTGAATTCTCAGCCGAGACTGGGAACCAGACTCTGCATAATTCTGAGTCT
CAGGCTTTGGAAGCAGGCGAGCCTCTGCTCACCCCCTACTGTATCCTCGGACTCCATGACTGGA
ATCGCCGACTACTGAATCTCTGGATTGCTGCTACTTCAAGCTCTCACACTTGAAACAAGACGAT
TTTCTTGGGGGCGGGGGGATGATAGCATCCAAATATTCAGAATTTTAGACCCTTCTGAGAAATG
ACCTTCTAGTAAGTGGCCATGAGAAACACTGCTTCTCAAGAGTGGTGCGTGCGTGTGTGTGTGT
GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTCTGTCTGTCTGTCT
GTCTGTCTGTCTCTGTGTGTGTGTCTGTCTGTGTGTGTCTTTGTATGCCTGTAGGTGGGTGACT
TTCTCAGGATTCCTAACTTGATTCAAATTATTGTTGAGTTTATGTAAAGAATTCATGTCTATAC
AGAAGAACAAGTGTGTTCGTTCACCCTAGGTTACAATGGTCTCCATTTCATTTCAGAGGAGAGA
ATCAGGCTATCTGAATATAAACACAATTTGATGTTAATTTATTCTAAGTACTCTGGGATTTTGA
TTGTCCTAAAGAATTCTGCTCTGTGAATACCATGTTAATTTTTTTTTTAATTTGTGGCAGGATT
GTAGCGAATTATTTAAGGAAAATAAATTACATGAATGCTTTAAGGTGGTATTTTTAAATAGCCG
TTTTTATGTATTGAGAAGAATGTCAGCAGGTTTCTTAATGGTATTAAGGGAAAAGGATACTTTA
ACGTTATCATGTATGAAGACGAAGCTACATAGATACTTACTTAACAGGTACGGGACCAATTAAA
GCATTTTCTAGTTGCAAGATGGGTAAGGACCTGTAGAAAGGATGCCAGGTTGTTAAACGTTCTT
TATTTGCAGGCTCAGTTTATGTGTCTACTTCCCCTGCCTGTCTTTTTACCCATGCACATCTTAA
TGCTCAGTGACATGAGTGGAAGGTGCCCAGTGCCCTGTACAATGAGAAACTGGAATTTGGTTCT
CTATGCCACTCAACATCAGGGAGCCCTCAGTCTAGGAACTTGGGATCTGTGCCTCTTTCTGTGT
CCAATAAAGAGAACCAACACTTGGGACTTGAGGGCACTCAAGAATTAGATCACACTATGAAAAC
TAATTTCCACCCTCTGGAATTTATAAACCAGTGCCACTGAAGTCCTAGGAAGGTTGACTTCTTT
GGTTGACCCTAAGTGCATCAGACAAGTGAAACCCACCGGGATTTCATAGAACAGTGTTGGGGGG
AGGAGTGGGGAGCACAGAAGACAGAGGACTGATACCTTTTCTCAGCCTGGATTCTGAGAACGCT
CTCAGTAAAGCACCGAAAAGAGGAGGAGTAGAGAGGGTGCTGGGTGCATTTCAGTGGTACCAGG
CTGTTTAACAAATCATCATTGTTTGATAGAAATGTTTATCACCACCCTGTGGGCAAACCACTTG
CAGAGTCTGAATGTCCTTGGAGATTGTTTTATTATTTTTCTGGAAACAAGTTGTTGAGTGTGGT
CATGAAAATGCTGCTGTTAGACTTACATAATATTCTGTGAAGCTTGAAAAAGCTGCAACTGCGC
TCGCTCGCTCTCTCTCCCTCCTCCTCCTCCTCCTTCCCTCCCTTTCTCCCTCTCCCTCCCTCCC
TCTCTCTCTCTCTCCTTCTTTCCCTTCCCCTCCCCCCTCTGCCATTGTATGGGGCCAGCAGTTC
AGACACAGCAGTCATTGCCAGAAACAAAATCCGTGGGATCTTGAGAAGGACAAGACAAGAAAAT
GACCCCAAGGAGCAGAATGCCCAGGTAAACTGGGTCATTATTACCACTTAAAAACAAAAGCTCC
GAGCTCCCATTTTCCTGCATCCCACACTTCACGGTTGCTTTTAAGAAGCTATGTTTCATCCTAA
GAATTGCATCAGGAGCAAGGCTAAATATTTTGCCTGGAAAATTTGGCTGGTTGTGAATGGAGAA
GGTATTTATATCCTACATTCCAGCACCTTCCCAAAGAGCAGATTAGACACCCCAGTGTACTTCC
TTCATCCGGGTGGGTTCCCTGCTGGTACCACTCTCCAGAACCCATGCGTGGTGTGTTGATTTTC
CAGAGAGAAAAATTAAGTGAAGTTCATTTAGTGGTGGGGAGGCAGGGTGGGTGGATCTCCAGCG
TGTAGCGGTATTTGTACTTTCCAGGGTGCCTTGGGACTTAAATGTGCCTCCAAGACTTGTGAGG
TTCTCTCAATGCTGTGCTCTTGATTGACCCTCTCCCCCTCCCCCCTGCATGCCTTTATCCTTCA
AAGTTACGATGGGGGGTGGGGGGGAGTAAGTAGCCTCTTCATCCTCCCAAGGCAACCGGGAGGC
AGCATCAGCAGGGAAGAATTAATGGGACGTAGTCCAGACCTGGGCCTGGGCGTCAGCCCTCAGC
CCCTCAGCCAGTTTCTGTTTGCTTGTGTTGAGAAGTGCTGATGACTGGGTAGAACAGATGAGGT
CAGTCACAGGTATATTTCAGGGAAACAAGATTCAACCTTAACCCGATCTGAAGAGCTGGCACAG
AGAAACACCCGGTCGGTCTGTGACTTGTCCCCAAGAGATTGGTTTTCTCAGCCCTTATCACTGT
GGAATTGCAAAGGTAGAGATCACCACCCTCCTGGTTCTTCACCTGTCATCCTAGAGCAGACCTA
GAAAAGACGGCCAAGTCCCTTGTGAGCTCAGCCTGAGCAATCAAACCCCGAAGACTGAGAATAG
CAATGTCGCTTGCTTGATAGCTCTCGTACCACTGGAGCAACCACAGGACTGTGCTAAGCCATAG
TTTTGTAAAGTTATCTTTAGTCAATCAGCAATATGTGTTCCTGTAAATTTGGAATGTTTTTCAT
TCTGACTTGTTGTCAGGGACTCTACTGAAAAACAACTTGATCAATATAAAAGCGTCCGAGCTAT
GCAACACTA

hide sequence

RefSeq Acc Id:

XM_008763740 ⟹ XP_008761962

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	76,703,687 - 76,765,452 (-)	NCBI
mRatBN7.2	5	71,910,793 - 71,970,317 (-)	NCBI
Rnor_6.0	5	74,251,269 - 74,311,597 (-)	NCBI

Sequence:

show sequence

TTAGTTCCTCAAGGAGATGCCCGTTTTCAGTCTGATTGATTGGCCTCCAAGCTGATTGAACCAG
GCATGCCTTTCAGCATTTACCCCATGTAATAAAATAAGCCATTCCCTCCCGTGTCTTTGAGGGA
GAGACGGGAGAGCTGATGGGGGTGGGTGGTCCTGGATTGAGACTGCTCTCCTTCCACATAGGGA
GTCGCCTTGGGACAAGCCTTGCCTCGTCCAAATACTACTTCCCACTCCTAGCCTCTTCTTCCCA
CTCCTCACGTGACTCAGTGTTACTGTGGCGGCAGCTGTTCTGTTCCCATTAAATGAGAACCACG
CCGACCCAGGCCAGCCCTCCAGAGACATCTCATTTCTTGGGAAGGGCCATAAAAACAAAGGGCA
AGCTAGCGGCGTACCTTCTCAGAGGGCGCCGCCAGCCCTTTCTCCCGGAATTGCTCCTGGGACA
GAAGTCAGCATCCTAAAATAGCACAGGGCCACTGGCGTTTGAAGCGTGTGGCCACTGTTGAGAG
GCTTGACAGGCAGAATGATCAGAGATTACCTATTAATCGAGCTCCATGGCATGACGAGAGGGCA
GGCATCTTGAAAGGGGATAGGCAGTTCTCACTGACCTCCCGGGGAGCCCACTAAGTGGGGAGGG
TGTCAGTCAAAAAACAGAGGGATCCAGAGGAGGTCCGGTTCTGTGGACAAGAAACAAAACCTGC
TTCATTAGGATTGAAAGCCTGAGTGCTTACGGGGACTGGCCCAAGGCACTTAGGAACTGTTAAT
AACTTACAGAGGGCCATTACAACGTTTTCCAGTGGGCTAAAGCAGTCAGAAGCCGAATCTTGCT
ACATCAACATAGCTCGAACCCTTGACTTCTACGGAGTGGAGCTTCATGGAGGCAGAGATCTACA
CAATTTAGATCTAATGATCGGAATTGCGTCTGCAGGCATCGCAGTGTACCGAAAATACATCTGC
ACAAGTTTCTACCCTTGGGTGAACATACTCAAAATTTCTTTCAAAAGGAAAAAGTTCTTCATAC
ACCAGCGGCAAAAGCAGGCTGAATCCAGGGAACATATCGTGGCCTTCAACATGCTGAATTACCG
ATCCTGCAAGAACTTGTGGAAATCCTGCGTGGAGCACCATTCGTTCTTTCAGGCAAAAAAGTTA
CTACCTCAGGAAAAGAATGTTCTGTCTCAGTACTGGACTCTAGGCTCCAGGAACCCCAAAAAGT
CTGTAAATAACCAATATTGCAAAAAGGTGATTGGAGGGATGGTGTGGAACCCAGTCATGAGGAG
ATCCTTATCGGTGGAACGGCTAGAAACCAAGAGTCTGCCTTCCCGGTCGCCTCCCATCACCCCC
AACTGGCGAAGTCCACGGCTCCGCCATGAAATCCGCAAGCCCCGCCATTCCTCCGCAGACAACC
TGGCCAATGAGATGACCTACATCACAGAAACGGAGGACGTGTTCTATACCTACAAGGGATCCCT
ATCCCCCAAAGACAGCGATTCCGAAGTTTCCCAGAACCACAGCCCACACCGGGGGAGTCTGTCT
GAAAACAACCCAGCCCAAAGCTGCCTGACCCAGAAGTCATCCAGTTCTGTGTCTCCATGTTCAA
ATGCACCAGGCTCCTTCTCCCCAGATGGAGTTGACCAGCAGTTCTTAGAAGACTACCACAAGGT
GACCAAAGGAGGCTCCATCGAGGAAGCCAGCCAGTACTACTGTGATAAGAATGACGATGGCGAT
GGCTACCTAGTCCTGATCCGGATCACACCAGATAAAGAGGGAAGATTTGGATTTAATCTTAAGG
GAGGAGTGGATCAAAAGATGCCGCTTGTGGTCTCGAGGATCAACCCAGAGTCCCCTGCGGATAC
CTGCATGCCGAAACTGAATGAAGGGGATCAGATCGTGCTGATCAATGGCCGGGACATCTCAGAG
CACACTCACGACCAGGTGGTGATGTTCATCAAAGCAAGCCGGGAGTCCCACTCGAGAGAATTGG
CCCTGGTGATCAGGAGGAAAGCTGTACGCTCGCTGGCGGAGATCAGATCGGAAGATGAGCTGAG
TCAGCTTTTCCCAGAAGCCATGTTTCCTGCGTGTCCTGAGGGTGGGGACAGTCTGGAGGGATCC
ATGGAGCTGTTAAAGAAAGGTCTGGAAAGCGGTACAGTGTTGATCCAGTTTGAGCAACTCTACA
GAAAGAAGCCCGGCTTGGCCGTCACATTTGCAAAGCTGCCTCAAAATTTGGATAAAAACCGATA
CAAAGATGTGTTGCCTTACGACACCACCCGGGTATTATTGCAGGGAAATGAAGATTATATTAAT
GCCAGTTATGTGAACATGGAGATTCCCGCTGCTAACCTTGTGAACAAGTACATTGCCACTCAGG
GACCGCTGCCACACACCTGTGCACAGTTTTGGCAAGTTGTCTGGGATCAGAAGTTGTCTCTTGT
TGTCATGCTGACAACTCTCACAGAGCGAGGGCGGACCAAATGTCACCAGTACTGGCCAGATCCC
CCTGACATCATGGACCACGGCATCTTTCACATCCAGTGTCAGGCAGAGGACTGTACCATTGCTT
ACGTGTCCCGAGAAATGCTTGTTACAAACACTGAGACCGGGGAAGAGCACACAGTGACCCATCT
CCAATATGTCGCGTGGCCTGACCACGGCGTGCCTGATGACTCCTCAGACTTCCTGGAGTTTGTG
AAGTACGTGAGGTCCCTGCGGGTAGGCGGTGAGCCTGCCCTTGTTCACTGCAGTGCGGGAATAG
GTCGAACAGGTGTATTGGTCACTATGGAAACAGCCATGTGCTTAATTGAGAGGAACCTGCCTGT
TTACCCACTGGATATTGTCCGGAAAATGAGAGACCAGCGCGCCATGATGGTGCAGACATCAAGC
CAATACAAGTTTGTGTGTGAAGCGATTCTTCGAGTGTATGAAGAAGGCTTAGTCCAGACGTTGG
ATCCCAGTTAGGACAACTGTGAAGTGGTCATTCCTCCTTCCCTAGGGCGACTTCCTGAACAAGG
GGACGCACATTCCCCTGGAGGCCTCCAGAGATGCTGGTCACTGTGGGAAAGGGATGAGCTTCTC
CGAACCCAGGCACTTTAAATTTCTGTGGAAAAGATATCCTGTACATAAGAACTGATATGTAGAT
GTGCATGCAGCTATGACTCCTTTGGGCCCAGAGATAAGCAACAGGGGATCTCCAGTTGGGAACT
GTGTTTCTCCCTACATATCACCGTCCCCCGTCATCCATCCTTGAGCAGTGAAAGGGGACACCAG
CAGTGCTGTTGACACCCCTCCCACCAGAAGCCAGACAACGTGGCTGCTTGTGGTTGCTCAAGTG
TTTTGTGTGTTGTTCTGTGTGGGACTCCAAGGGCTGAACTTGCTTGGCAATTGGTGTCCATTAC
CCCTGACACCAGGGAAAACTCAGATGAATGTAACACAGGCAGGGCACAAGGGACTTCAGGCCGG
AGGATAAACAGGATCTATTCTGCCCTCCCTCCCTCCTTCTGCCTCATCTCTACCCCTTCTGCCA
CCCAAAGCACCCCGTTTCCCCACCCCGAATTCCTTCTCTTCAGGATCACGCCCAGTGCCTGAAC
CAGTCTCATGATGTATGTTCAGGTGAATTCTCAGCCGAGACTGGGAACCAGACTCTGCATAATT
CTGAGTCTCAGGCTTTGGAAGCAGGCGAGCCTCTGCTCACCCCCTACTGTATCCTCGGACTCCA
TGACTGGAATCGCCGACTACTGAATCTCTGGATTGCTGCTACTTCAAGCTCTCACACTTGAAAC
AAGACGATTTTCTTGGGGGCGGGGGGATGATAGCATCCAAATATTCAGAATTTTAGACCCTTCT
GAGAAATGACCTTCTAGTAAGTGGCCATGAGAAACACTGCTTCTCAAGAGTGGTGCGTGCGTGT
GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTCTGTCT
GTCTGTCTGTCTGTCTGTCTCTGTGTGTGTGTCTGTCTGTGTGTGTCTTTGTATGCCTGTAGGT
GGGTGACTTTCTCAGGATTCCTAACTTGATTCAAATTATTGTTGAGTTTATGTAAAGAATTCAT
GTCTATACAGAAGAACAAGTGTGTTCGTTCACCCTAGGTTACAATGGTCTCCATTTCATTTCAG
AGGAGAGAATCAGGCTATCTGAATATAAACACAATTTGATGTTAATTTATTCTAAGTACTCTGG
GATTTTGATTGTCCTAAAGAATTCTGCTCTGTGAATACCATGTTAATTTTTTTTTTAATTTGTG
GCAGGATTGTAGCGAATTATTTAAGGAAAATAAATTACATGAATGCTT

hide sequence

RefSeq Acc Id:

XM_017593736 ⟹ XP_017449225

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	76,703,687 - 76,822,584 (-)	NCBI
mRatBN7.2	5	71,910,793 - 72,027,323 (-)	NCBI
Rnor_6.0	5	74,251,269 - 74,368,167 (-)	NCBI

Sequence:

show sequence

TGGGACAGGGACTGGGACGTCAGGCACGGCGGAGGGTCTCATGGTGACATGGGAACAAAAGGTT
CTCAGGATATCTAGCACCCAGGTTACTCGGCGGCCGTTATGACCTCCCGGTTACGTGCGTTGGG
TGGAAGAATTAATAATATACGGACCTCAGAATTGCCCAAAGAGAAAACTCGATCCGAGGTCACC
TGCAGCATACGCTTTTTAGATGGCTTGGTACAGACCTTTAAAGTTAATAAACAAGATTTGGGCC
AGTCACTTCTGGATATGGCCTATGGCCACCTGGGCGTGACGGAGAAGGAATACTTCGGCTTGCA
ACATGGCGATGACCCAGTGGACTCCCCCAGATGGCTCGAGGCAAGCAAACCCCTCAGGAAGCAG
CTGAAAGGAGGTCTCCCCTGTATCCTGCATTTTCGAGTAAGATATTTTATACCTGACCCCAACA
CGCTGCAGCAGGAACAAACCAGGCATTTGTATTTCTTACAACTGAAGATGGATGTTTGTGAAGG
AAGGTTAACCTGCCCTCTCAACTCAGCGGTGGTTCTAGCATCCTATGCAGTGCAATCTCATATC
GGAGACTTTAATTCTTCCATACATCATCCAGGCTATCTTGCCGACAGCCAGTTCATACCAGATC
AAAATGATGACTTTCTAAGCAAGGTGGAGTCACTCCACGAACAGCACAGTGGGCTAAAGCAGTC
AGAAGCCGAATCTTGCTACATCAACATAGCTCGAACCCTTGACTTCTACGGAGTGGAGCTTCAT
GGAGGCAGAGATCTACACAATTTAGATCTAATGATCGGAATTGCGTCTGCAGGCATCGCAGTGT
ACCGAAAATACATCTGCACAAGTTTCTACCCTTGGGTGAACATACTCAAAATTTCTTTCAAAAG
GAAAAAGTTCTTCATACACCAGCGGCAAAAGCAGGCTGAATCCAGGGAACATATCGTGGCCTTC
AACATGCTGAATTACCGATCCTGCAAGAACTTGTGGAAATCCTGCGTGGAGCACCATTCGTTCT
TTCAGGCAAAAAAGTTACTACCTCAGGAAAAGAATGTTCTGTCTCAGTACTGGACTCTAGGCTC
CAGGAACCCCAAAAAGTCTGTAAATAACCAATATTGCAAAAAGGTGATTGGAGGGATGGTGTGG
AACCCAGTCATGAGGAGATCCTTATCGGTGGAACGGCTAGAAACCAAGAGTCTGCCTTCCCGGT
CGCCTCCCATCACCCCCAACTGGCGAAGTCCACGGCTCCGCCATGAAATCCGCAAGCCCCGCCA
TTCCTCCGCAGACAACCTGGCCAATGAGATGACCTACATCACAGAAACGGAGGACGTGTTCTAT
ACCTACAAGGGATCCCTATCCCCCAAAGACAGCGATTCCGAAGTTTCCCAGAACCACAGCCCAC
ACCGGGGGAGTCTGTCTGAAAACAACCCAGCCCAAAGCTGCCTGACCCAGAAGTCATCCAGTTC
TGTGTCTCCATGTTCAAATGCACCAGGCTCCTTCTCCCCAGATGGAGTTGACCAGCAGTTCTTA
GAAGACTACCACAAGGTGACCAAAGGAGGCTCCATCGAGGAAGCCAGCCAGTACTACTGTGATA
AGAATGACGATGGCGATGGCTACCTAGTCCTGATCCGGATCACACCAGATAAAGAGGGAAGATT
TGGATTTAATCTTAAGGGAGGAGTGGATCAAAAGATGCCGCTTGTGGTCTCGAGGATCAACCCA
GAGTCCCCTGCGGATACCTGCATGCCGAAACTGAATGAAGGGGATCAGATCGTGCTGATCAATG
GCCGGGACATCTCAGAGCACACTCACGACCAGGTGGTGATGTTCATCAAAGCAAGCCGGGAGTC
CCACTCGAGAGAATTGGCCCTGGTGATCAGGAGGAAAGCTGTACGCTCGCTGGCGGAGATCAGA
TCGGAAGATGAGCTGAGTCAGCTTTTCCCAGAAGCCATGTTTCCTGCGTGTCCTGAGGGTGGGG
ACAGTCTGGAGGGATCCATGGAGCTGTTAAAGAAAGGTCTGGAAAGCGGTACAGTGTTGATCCA
GTTTGAGCAACTCTACAGAAAGAAGCCCGGCTTGGCCGTCACATTTGCAAAGCTGCCTCAAAAT
TTGGATAAAAACCGATACAAAGATGTGTTGCCTTACGACACCACCCGGGTATTATTGCAGGGAA
ATGAAGATTATATTAATGCCAGTTATGTGAACATGGAGATTCCCGCTGCTAACCTTGTGAACAA
GTACATTGCCACTCAGGGACCGCTGCCACACACCTGTGCACAGTTTTGGCAAGTTGTCTGGGAT
CAGAAGTTGTCTCTTGTTGTCATGCTGACAACTCTCACAGAGCGAGGGCGGACCAAATGTCACC
AGTACTGGCCAGATCCCCCTGACATCATGGACCACGGCATCTTTCACATCCAGTGTCAGGCAGA
GGACTGTACCATTGCTTACGTGTCCCGAGAAATGCTTGTTACAAACACTGAGACCGGGGAAGAG
CACACAGTGACCCATCTCCAATATGTCGCGTGGCCTGACCACGGCGTGCCTGATGACTCCTCAG
ACTTCCTGGAGTTTGTGAAGTACGTGAGGTCCCTGCGGGTAGGCGGTGAGCCTGCCCTTGTTCA
CTGCAGTGCGGGAATAGGTCGAACAGGTGTATTGGTCACTATGGAAACAGCCATGTGCTTAATT
GAGAGGAACCTGCCTGTTTACCCACTGGATATTGTCCGGAAAATGAGAGACCAGCGCGCCATGA
TGGTGCAGACATCAAGCCAATACAAGTTTGTGTGTGAAGCGATTCTTCGAGTGTATGAAGAAGG
CTTAGTCCAGACGTTGGATCCCAGTTAGGACAACTGTGAAGTGGTCATTCCTCCTTCCCTAGGG
CGACTTCCTGAACAAGGGGACGCACATTCCCCTGGAGGCCTCCAGAGATGCTGGTCACTGTGGG
AAAGGGATGAGCTTCTCCGAACCCAGGCACTTTAAATTTCTGTGGAAAAGATATCCTGTACATA
AGAACTGATATGTAGATGTGCATGCAGCTATGACTCCTTTGGGCCCAGAGATAAGCAACAGGGG
ATCTCCAGTTGGGAACTGTGTTTCTCCCTACATATCACCGTCCCCCGTCATCCATCCTTGAGCA
GTGAAAGGGGACACCAGCAGTGCTGTTGACACCCCTCCCACCAGAAGCCAGACAACGTGGCTGC
TTGTGGTTGCTCAAGTGTTTTGTGTGTTGTTCTGTGTGGGACTCCAAGGGCTGAACTTGCTTGG
CAATTGGTGTCCATTACCCCTGACACCAGGGAAAACTCAGATGAATGTAACACAGGCAGGGCAC
AAGGGACTTCAGGCCGGAGGATAAACAGGATCTATTCTGCCCTCCCTCCCTCCTTCTGCCTCAT
CTCTACCCCTTCTGCCACCCAAAGCACCCCGTTTCCCCACCCCGAATTCCTTCTCTTCAGGATC
ACGCCCAGTGCCTGAACCAGTCTCATGATGTATGTTCAGGTGAATTCTCAGCCGAGACTGGGAA
CCAGACTCTGCATAATTCTGAGTCTCAGGCTTTGGAAGCAGGCGAGCCTCTGCTCACCCCCTAC
TGTATCCTCGGACTCCATGACTGGAATCGCCGACTACTGAATCTCTGGATTGCTGCTACTTCAA
GCTCTCACACTTGAAACAAGACGATTTTCTTGGGGGCGGGGGGATGATAGCATCCAAATATTCA
GAATTTTAGACCCTTCTGAGAAATGACCTTCTAGTAAGTGGCCATGAGAAACACTGCTTCTCAA
GAGTGGTGCGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG
TGTGTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTCTGTGTGTGTGTCTGTCTGTGTGTGTC
TTTGTATGCCTGTAGGTGGGTGACTTTCTCAGGATTCCTAACTTGATTCAAATTATTGTTGAGT
TTATGTAAAGAATTCATGTCTATACAGAAGAACAAGTGTGTTCGTTCACCCTAGGTTACAATGG
TCTCCATTTCATTTCAGAGGAGAGAATCAGGCTATCTGAATATAAACACAATTTGATGTTAATT
TATTCTAAGTACTCTGGGATTTTGATTGTCCTAAAGAATTCTGCTCTGTGAATACCATGTTAAT
TTTTTTTTTAATTTGTGGCAGGATTGTAGCGAATTATTTAAGGAAAATAAATTACATGAATGCT
T

hide sequence

RefSeq Acc Id:

XM_039111038 ⟹ XP_038966966

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	76,703,687 - 76,800,540 (-)	NCBI
mRatBN7.2	5	71,910,793 - 72,005,372 (-)	NCBI

RefSeq Acc Id:

XM_063287932 ⟹ XP_063144002

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	76,703,687 - 76,802,244 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001094224	(Get FASTA)	NCBI Sequence Viewer
	XP_001059757	(Get FASTA)	NCBI Sequence Viewer
	XP_008761962	(Get FASTA)	NCBI Sequence Viewer
	XP_017449225	(Get FASTA)	NCBI Sequence Viewer
	XP_038966966	(Get FASTA)	NCBI Sequence Viewer
	XP_063144002	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH92605	(Get FASTA)	NCBI Sequence Viewer
	EDL91675	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000056382.3
	ENSRNOP00000068051.2
	ENSRNOP00000068252
	ENSRNOP00000068252.2
	ENSRNOP00000077016
	ENSRNOP00000077016.1
	ENSRNOP00000081216.1
	ENSRNOP00000101241

RefSeq Acc Id:	XP_001059757 ⟸ XM_001059757
- Peptide Label:	isoform X1
- UniProtKB:	F1LQQ5 (UniProtKB/TrEMBL), A6KDS9 (UniProtKB/TrEMBL), A0A096MJA1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGRKVQSERRKAGVGGGGRGRLERRPLGALKALGRANLPGVLGPAKEPRDSQLSHGAAGVGATP NSATEPPSKARCHFRFVVRQALAIPRHAIPESQAHSYSAAVMTSRLRALGGRINNIRTSELPKE KTRSEVTCSIRFLDGLVQTFKVNKQDLGQSLLDMAYGHLGVTEKEYFGLQHGDDPVDSPRWLEA SKPLRKQLKGGLPCILHFRVRYFIPDPNTLQQEQTRHLYFLQLKMDVCEGRLTCPLNSAVVLAS YAVQSHIGDFNSSIHHPGYLADSQFIPDQNDDFLSKVESLHEQHSGLKQSEAESCYINIARTLD FYGVELHGGRDLHNLDLMIGIASAGIAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAES REHIVAFNMLNYRSCKNLWKSCVEHHSFFQAKKLLPQEKNVLSQYWTLGSRNPKKSVNNQYCKK VIGGMVWNPVMRRSLSVERLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYIT ETEDVFYTYKGSLSPKDSDSEVSQNHSPHRGSLSENNPAQSCLTQKSSSSVSPCSNAPGSFSPD GVDQQFLEDYHKVTKGGSIEEASQYYCDKNDDGDGYLVLIRITPDKEGRFGFNLKGGVDQKMPL VVSRINPESPADTCMPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRKAV RSLAEIRSEDELSQLFPEAMFPACPEGGDSLEGSMELLKKGLESGTVLIQFEQLYRKKPGLAVT FAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQ FWQVVWDQKLSLVVMLTTLTERGRTKCHQYWPDPPDIMDHGIFHIQCQAEDCTIAYVSREMLVT NTETGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVKYVRSLRVGGEPALVHCSAGIGRTGVLVTM ETAMCLIERNLPVYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQTLDPS hide sequence

RefSeq Acc Id:

XP_008761962 ⟸ XM_008763740

- Peptide Label:

isoform X4

- Sequence:

show sequence

MIGIASAGIAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKN
LWKSCVEHHSFFQAKKLLPQEKNVLSQYWTLGSRNPKKSVNNQYCKKVIGGMVWNPVMRRSLSV
ERLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLSPKD
SDSEVSQNHSPHRGSLSENNPAQSCLTQKSSSSVSPCSNAPGSFSPDGVDQQFLEDYHKVTKGG
SIEEASQYYCDKNDDGDGYLVLIRITPDKEGRFGFNLKGGVDQKMPLVVSRINPESPADTCMPK
LNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRKAVRSLAEIRSEDELSQLFP
EAMFPACPEGGDSLEGSMELLKKGLESGTVLIQFEQLYRKKPGLAVTFAKLPQNLDKNRYKDVL
PYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLVVMLT
TLTERGRTKCHQYWPDPPDIMDHGIFHIQCQAEDCTIAYVSREMLVTNTETGEEHTVTHLQYVA
WPDHGVPDDSSDFLEFVKYVRSLRVGGEPALVHCSAGIGRTGVLVTMETAMCLIERNLPVYPLD
IVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQTLDPS

hide sequence

RefSeq Acc Id:	XP_017449225 ⟸ XM_017593736
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5YBL2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTSRLRALGGRINNIRTSELPKEKTRSEVTCSIRFLDGLVQTFKVNKQDLGQSLLDMAYGHLGV TEKEYFGLQHGDDPVDSPRWLEASKPLRKQLKGGLPCILHFRVRYFIPDPNTLQQEQTRHLYFL QLKMDVCEGRLTCPLNSAVVLASYAVQSHIGDFNSSIHHPGYLADSQFIPDQNDDFLSKVESLH EQHSGLKQSEAESCYINIARTLDFYGVELHGGRDLHNLDLMIGIASAGIAVYRKYICTSFYPWV NILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHSFFQAKKLLPQEKNV LSQYWTLGSRNPKKSVNNQYCKKVIGGMVWNPVMRRSLSVERLETKSLPSRSPPITPNWRSPRL RHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLSPKDSDSEVSQNHSPHRGSLSENNPAQS CLTQKSSSSVSPCSNAPGSFSPDGVDQQFLEDYHKVTKGGSIEEASQYYCDKNDDGDGYLVLIR ITPDKEGRFGFNLKGGVDQKMPLVVSRINPESPADTCMPKLNEGDQIVLINGRDISEHTHDQVV MFIKASRESHSRELALVIRRKAVRSLAEIRSEDELSQLFPEAMFPACPEGGDSLEGSMELLKKG LESGTVLIQFEQLYRKKPGLAVTFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNME IPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLVVMLTTLTERGRTKCHQYWPDPPDIMDHG IFHIQCQAEDCTIAYVSREMLVTNTETGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVKYVRSLR VGGEPALVHCSAGIGRTGVLVTMETAMCLIERNLPVYPLDIVRKMRDQRAMMVQTSSQYKFVCE AILRVYEEGLVQTLDPS hide sequence

Ensembl Acc Id:

ENSRNOP00000056382 ⟸ ENSRNOT00000059627

Ensembl Acc Id:

ENSRNOP00000068051 ⟸ ENSRNOT00000076106

Ensembl Acc Id:

ENSRNOP00000068252 ⟸ ENSRNOT00000076705

RefSeq Acc Id:	XP_038966966 ⟸ XM_039111038
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5YBL2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000077016 ⟸ ENSRNOT00000104839

Ensembl Acc Id:

ENSRNOP00000081216 ⟸ ENSRNOT00000096667

RefSeq Acc Id:	NP_001094224 ⟸ NM_001100754
- UniProtKB:	A0A8I5YBL2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063144002 ⟸ XM_063287932
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5YBL2 (UniProtKB/TrEMBL)

Protein Domains

FERM PDZ Tyrosine specific protein phosphatases Tyrosine-protein phosphatase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LQQ5-F1-model_v2	AlphaFold	F1LQQ5	1-1018	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693759

Promoter ID:

EPDNEW_R4282

Type:

multiple initiation site

Name:

Ptpn3_1

Description:

protein tyrosine phosphatase, non-receptor type 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4283

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	74,366,841 - 74,366,901	EPDNEW

RGD ID:

13693760

Promoter ID:

EPDNEW_R4283

Type:

initiation region

Name:

Ptpn3_2

Description:

protein tyrosine phosphatase, non-receptor type 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R4282

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	74,367,253 - 74,367,313	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311363	AgrOrtholog
BioCyc Gene	G2FUF-41211	BioCyc
Ensembl Genes	ENSRNOG00000011425	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000059627.5	UniProtKB/TrEMBL
	ENSRNOT00000076106.3	UniProtKB/TrEMBL
	ENSRNOT00000076705	ENTREZGENE
	ENSRNOT00000076705.2	UniProtKB/TrEMBL
	ENSRNOT00000096667.1	UniProtKB/TrEMBL
	ENSRNOT00000104839	ENTREZGENE
	ENSRNOT00000104839.1	UniProtKB/TrEMBL
	ENSRNOT00000158623	ENTREZGENE
Gene3D-CATH	1.20.80.10	UniProtKB/TrEMBL
	2.30.29.30	UniProtKB/TrEMBL
	2.30.42.10	UniProtKB/TrEMBL
	3.90.190.10	UniProtKB/TrEMBL
	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7308722	IMAGE-MGC_LOAD
InterPro	Band_41_domain	UniProtKB/TrEMBL
	FERM/acyl-CoA-bd_prot_3-hlx	UniProtKB/TrEMBL
	FERM_2	UniProtKB/TrEMBL
	FERM_central	UniProtKB/TrEMBL
	FERM_CS	UniProtKB/TrEMBL
	FERM_domain	UniProtKB/TrEMBL
	FERM_N	UniProtKB/TrEMBL
	FERM_PH-like_C	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	PDZ_sf	UniProtKB/TrEMBL
	PH_like_dom	UniProtKB/TrEMBL
	Prot-tyrosine_phosphatase-like	UniProtKB/TrEMBL
	PTPN3/4_FERM_C	UniProtKB/TrEMBL
	Tyr/Dual-specificity_Pase	UniProtKB/TrEMBL
	Tyr_Pase_AS	UniProtKB/TrEMBL
	Tyr_Pase_cat	UniProtKB/TrEMBL
	Tyr_Pase_non-rcpt_typ-3/4	UniProtKB/TrEMBL
	Tyr_Pase_rcpt/non-rcpt	UniProtKB/TrEMBL
	Ubiquitin-rel_dom	UniProtKB/TrEMBL
KEGG Report	rno:362524	UniProtKB/TrEMBL
MGC_CLONE	MGC:109219	IMAGE-MGC_LOAD
NCBI Gene	362524	ENTREZGENE
PANTHER	TYROSINE-PROTEIN PHOSPHATASE	UniProtKB/TrEMBL
	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 3	UniProtKB/TrEMBL
Pfam	FERM_C	UniProtKB/TrEMBL
	FERM_M	UniProtKB/TrEMBL
	FERM_N	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	Y_phosphatase	UniProtKB/TrEMBL
PhenoGen	Ptpn3	PhenoGen
PIRSF	Tyr-Ptase_nr3	UniProtKB/TrEMBL
PRINTS	BAND41	UniProtKB/TrEMBL
	PRTYPHPHTASE	UniProtKB/TrEMBL
PROSITE	FERM_2	UniProtKB/TrEMBL
	FERM_3	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_1	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_2	UniProtKB/TrEMBL
	TYR_PHOSPHATASE_PTP	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000011425	RatGTEx
SMART	B41	UniProtKB/TrEMBL
	FERM_C	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	PTPc	UniProtKB/TrEMBL
	PTPc_motif	UniProtKB/TrEMBL
Superfamily-SCOP	FERM_3-hlx	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	PH domain-like	UniProtKB/TrEMBL
	SSF52799	UniProtKB/TrEMBL
	SSF54236	UniProtKB/TrEMBL
UniProt	A0A096MJA1	ENTREZGENE, UniProtKB/TrEMBL
	A0A096MJT2_RAT	UniProtKB/TrEMBL
	A0A8I5YBL2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZUL2_RAT	UniProtKB/TrEMBL
	A6KDS9	ENTREZGENE, UniProtKB/TrEMBL
	F1LQQ5	ENTREZGENE, UniProtKB/TrEMBL
	Q562B7_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Ptpn3	protein tyrosine phosphatase, non-receptor type 3	Ptpn3_predicted	protein tyrosine phosphatase, non-receptor type 3 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Ptpn3_predicted	protein tyrosine phosphatase, non-receptor type 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD