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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Acyp1 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Acyp1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ACYP1 mRNA | CTD | PMID:36331819 | Acyp1 | Rat | 1,2-dichloroethane | decreases expression | ISO | Acyp1 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of ACYP1 mRNA | CTD | PMID:28960355 | Acyp1 | Rat | 17beta-estradiol | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Estradiol affects the expression of ACYP1 mRNA | CTD | PMID:22574217 | Acyp1 | Rat | 17beta-estradiol | decreases expression | ISO | Acyp1 (Mus musculus) | 6480464 | Estradiol results in decreased expression of ACYP1 mRNA | CTD | PMID:39298647 | Acyp1 | Rat | 17beta-estradiol | multiple interactions | ISO | ACYP1 (Homo sapiens) | 6480464 | Estradiol promotes the reaction [ACYP1 protein binds to ESR1 protein] | CTD | PMID:27156127 | Acyp1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ACYP1 mRNA | CTD | PMID:33387578 | Acyp1 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of ACYP1 mRNA | CTD | PMID:21346803 | Acyp1 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2,6-dinitrotoluene affects the expression of ACYP1 mRNA | CTD | PMID:21346803 | Acyp1 | Rat | 2-palmitoylglycerol | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of ACYP1 mRNA | CTD | PMID:37199045 | Acyp1 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Acyp1 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of ACYP1 mRNA | CTD | PMID:18648102 | Acyp1 | Rat | aflatoxin B1 | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of ACYP1 protein | CTD | PMID:20106945 | Acyp1 | Rat | all-trans-retinoic acid | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ACYP1 mRNA | CTD | PMID:33167477 | Acyp1 | Rat | amiodarone | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of ACYP1 mRNA | CTD | PMID:19774075 | Acyp1 | Rat | arsenous acid | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of ACYP1 mRNA | CTD | PMID:26705709 | Acyp1 | Rat | benzo[a]pyrene | increases methylation | ISO | ACYP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ACYP1 promoter | CTD | PMID:27901495 | Acyp1 | Rat | benzo[a]pyrene | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ACYP1 mRNA | CTD | PMID:32234424 | Acyp1 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in decreased expression of ACYP1 mRNA | CTD | PMID:26496021 | Acyp1 | Rat | bisphenol A | decreases expression | ISO | Acyp1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ACYP1 mRNA | CTD | PMID:35598803 | Acyp1 | Rat | bisphenol A | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ACYP1 protein | CTD | PMID:37567409 | Acyp1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ACYP1 gene | CTD | PMID:28505145 | Acyp1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ACYP1 mRNA | CTD | PMID:25181051 | Acyp1 | Rat | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of ACYP1 protein | CTD | PMID:28903499 | Acyp1 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of ACYP1 promoter | CTD | PMID:22457795 | Acyp1 | Rat | cadmium dichloride | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of ACYP1 mRNA | CTD | PMID:38568856 | Acyp1 | Rat | carbamazepine | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of ACYP1 mRNA | CTD | PMID:25979313 | Acyp1 | Rat | CGP 52608 | multiple interactions | ISO | ACYP1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ACYP1 gene] | CTD | PMID:28238834 | Acyp1 | Rat | cobalt dichloride | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of ACYP1 mRNA | CTD | PMID:19376846 | Acyp1 | Rat | copper(II) sulfate | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Copper Sulfate affects the expression of ACYP1 mRNA | CTD | PMID:19549813 | Acyp1 | Rat | coumestrol | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of ACYP1 mRNA | CTD | PMID:19167446 | Acyp1 | Rat | coumestrol | multiple interactions | ISO | ACYP1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ACYP1 mRNA; [Coumestrol co-treated with resveratrol] more ... | CTD | PMID:19167446 | Acyp1 | Rat | crocidolite asbestos | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in increased expression of ACYP1 mRNA | CTD | PMID:29523930 | Acyp1 | Rat | cyclosporin A | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ACYP1 mRNA | CTD | PMID:21632981 | Acyp1 | Rat | cyclosporin A | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Cyclosporine affects the expression of ACYP1 mRNA | CTD | PMID:20106945|PMID:25562108 | Acyp1 | Rat | diarsenic trioxide | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of ACYP1 mRNA | CTD | PMID:26705709 | Acyp1 | Rat | Dibutyl phosphate | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ACYP1 mRNA | CTD | PMID:37042841 | Acyp1 | Rat | dioxygen | multiple interactions | ISO | Acyp1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ACYP1 mRNA | CTD | PMID:30529165 | Acyp1 | Rat | Enterolactone | multiple interactions | ISO | ACYP1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ACYP1 mRNA | CTD | PMID:19167446 | Acyp1 | Rat | epoxiconazole | decreases expression | ISO | Acyp1 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of ACYP1 mRNA | CTD | PMID:35436446 | Acyp1 | Rat | ethyl methanesulfonate | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of ACYP1 mRNA | CTD | PMID:23649840 | Acyp1 | Rat | folic acid | decreases expression | ISO | Acyp1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of ACYP1 mRNA | CTD | PMID:25629700 | Acyp1 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of ACYP1 mRNA | CTD | PMID:22061828 | Acyp1 | Rat | hydrogen peroxide | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of ACYP1 mRNA | CTD | PMID:20044591 | Acyp1 | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of ACYP1 mRNA | CTD | PMID:21396975 | Acyp1 | Rat | ivermectin | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ACYP1 protein | CTD | PMID:32959892 | Acyp1 | Rat | lead(0) | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Lead affects the expression of ACYP1 mRNA | CTD | PMID:28903495 | Acyp1 | Rat | leflunomide | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of ACYP1 mRNA | CTD | PMID:28988120 | Acyp1 | Rat | methidathion | decreases expression | ISO | Acyp1 (Mus musculus) | 6480464 | methidathion results in decreased expression of ACYP1 mRNA | CTD | PMID:34813904 | Acyp1 | Rat | methyl methanesulfonate | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of ACYP1 mRNA | CTD | PMID:23649840 | Acyp1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ACYP1 mRNA | CTD | PMID:25729387 | Acyp1 | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of ACYP1 mRNA | CTD | PMID:25729387 | Acyp1 | Rat | ozone | multiple interactions | ISO | Acyp1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Acyp1 | Rat | paracetamol | affects expression | ISO | Acyp1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ACYP1 mRNA | CTD | PMID:17562736 | Acyp1 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ACYP1 mRNA | CTD | PMID:33387578 | Acyp1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ACYP1 mRNA | CTD | PMID:30723492 | Acyp1 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Acyp1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of ACYP1 mRNA | CTD | PMID:37995155 | Acyp1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Acyp1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ACYP1 mRNA | CTD | PMID:36331819 | Acyp1 | Rat | pirinixic acid | decreases expression | ISO | Acyp1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ACYP1 mRNA | CTD | PMID:18445702 | Acyp1 | Rat | pirinixic acid | increases expression | ISO | Acyp1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of ACYP1 mRNA | CTD | PMID:17426115|PMID:18301758 | Acyp1 | Rat | quercetin | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Quercetin results in increased expression of ACYP1 mRNA | CTD | PMID:21632981 | Acyp1 | Rat | resorcinol | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | resorcinol results in increased expression of ACYP1 mRNA | CTD | PMID:22623647 | Acyp1 | Rat | resveratrol | multiple interactions | ISO | ACYP1 (Homo sapiens) | 6480464 | [Coumestrol co-treated with Resveratrol] results in increased expression of ACYP1 mRNA; [Plant Extracts co-treated with more ... | CTD | PMID:19167446|PMID:23557933 | Acyp1 | Rat | resveratrol | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | resveratrol results in increased expression of ACYP1 mRNA | CTD | PMID:19167446 | Acyp1 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of ACYP1 mRNA | CTD | PMID:19013527 | Acyp1 | Rat | sodium arsenite | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ACYP1 mRNA | CTD | PMID:28595984 | Acyp1 | Rat | sodium arsenite | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of ACYP1 mRNA | CTD | PMID:34032870 | Acyp1 | Rat | sodium arsenite | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ACYP1 mRNA | CTD | PMID:38568856 | Acyp1 | Rat | sunitinib | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ACYP1 mRNA | CTD | PMID:31533062 | Acyp1 | Rat | temozolomide | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of ACYP1 mRNA | CTD | PMID:31758290 | Acyp1 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of ACYP1 mRNA | CTD | PMID:15336504 | Acyp1 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in decreased expression of ACYP1 mRNA | CTD | PMID:26496021 | Acyp1 | Rat | tetrachloromethane | decreases expression | ISO | Acyp1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of ACYP1 mRNA | CTD | PMID:31919559 | Acyp1 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ACYP1 mRNA | CTD | PMID:33387578 | Acyp1 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of ACYP1 mRNA | CTD | PMID:34492290 | Acyp1 | Rat | toluene 2,4-diisocyanate | increases expression | ISO | Acyp1 (Mus musculus) | 6480464 | Toluene 2,4-Diisocyanate results in increased expression of ACYP1 mRNA | CTD | PMID:11379042 | Acyp1 | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of ACYP1 mRNA | CTD | PMID:25729387 | Acyp1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ACYP1 mRNA | CTD | PMID:25729387 | Acyp1 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of ACYP1 mRNA | CTD | PMID:33387578 | Acyp1 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of ACYP1 mRNA | CTD | PMID:30589522 | Acyp1 | Rat | triphenyl phosphate | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ACYP1 mRNA | CTD | PMID:37042841 | Acyp1 | Rat | tungsten | increases expression | ISO | Acyp1 (Mus musculus) | 6480464 | Tungsten results in increased expression of ACYP1 mRNA | CTD | PMID:30912803 | Acyp1 | Rat | valproic acid | increases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ACYP1 mRNA | CTD | PMID:29154799 | Acyp1 | Rat | valproic acid | decreases expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ACYP1 mRNA | CTD | PMID:23179753 | Acyp1 | Rat | valproic acid | affects expression | ISO | ACYP1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ACYP1 mRNA | CTD | PMID:25979313 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