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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nek7 | Rat | Weight Gain | | ISO | NEK7 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:19030233 | |
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nek7 | Rat | Weight Gain | | ISO | NEK7 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:19030233 | |
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# | Reference Title | Reference Citation |
1. | Identification of the NIMA family kinases NEK6/7 as regulators of the p70 ribosomal S6 kinase. | Belham C, etal., Curr Biol. 2001 Aug 7;11(15):1155-67. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:12840024 | PMID:21531765 | PMID:26188091 | PMID:31505169 | PMID:34414459 |
Nek7 (Rattus norvegicus - Norway rat) |
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NEK7 (Homo sapiens - human) |
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Nek7 (Mus musculus - house mouse) |
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Nek7 (Chinchilla lanigera - long-tailed chinchilla) |
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NEK7 (Pan paniscus - bonobo/pygmy chimpanzee) |
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NEK7 (Canis lupus familiaris - dog) |
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Nek7 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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NEK7 (Sus scrofa - pig) |
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NEK7 (Chlorocebus sabaeus - green monkey) |
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Nek7 (Heterocephalus glaber - naked mole-rat) |
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Variants in Nek7
783 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
BF386197 |
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RH136376 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_001108346 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_017598846 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272469 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272470 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063272471 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | CH473958 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
JAXUCZ010000013 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000000817 ⟹ ENSRNOP00000000817 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000090162 ⟹ ENSRNOP00000069169 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000095155 ⟹ ENSRNOP00000086821 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000098011 ⟹ ENSRNOP00000093817 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001108346 ⟹ NP_001101816 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063272469 ⟹ XP_063128539 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272470 ⟹ XP_063128540 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063272471 ⟹ XP_063128541 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001101816 | (Get FASTA) | NCBI Sequence Viewer |
XP_063128539 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128540 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063128541 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | D3ZBE5 | (Get FASTA) | NCBI Sequence Viewer |
EDM09639 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000000817.4 | ||
ENSRNOP00000069169.1 | |||
ENSRNOP00000086821.1 | |||
ENSRNOP00000093817.1 |
RefSeq Acc Id: | NP_001101816 ⟸ NM_001108346 |
- UniProtKB: | D3ZBE5 (UniProtKB/Swiss-Prot), A0A0G2JUP0 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000069169 ⟸ ENSRNOT00000090162 |
Ensembl Acc Id: | ENSRNOP00000000817 ⟸ ENSRNOT00000000817 |
Ensembl Acc Id: | ENSRNOP00000093817 ⟸ ENSRNOT00000098011 |
Ensembl Acc Id: | ENSRNOP00000086821 ⟸ ENSRNOT00000095155 |
RefSeq Acc Id: | XP_063128540 ⟸ XM_063272470 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A8I6AKB8 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063128539 ⟸ XM_063272469 |
- Peptide Label: | isoform X1 |
- UniProtKB: | D3ZBE5 (UniProtKB/Swiss-Prot), A0A0G2JUP0 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063128541 ⟸ XM_063272471 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A8I6AKB8 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-D3ZBE5-F1-model_v2 | AlphaFold | D3ZBE5 | 1-302 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1311160 | AgrOrtholog |
BioCyc Gene | G2FUF-18102 | BioCyc |
Ensembl Genes | ENSRNOG00000000657 | Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000000817.7 | UniProtKB/Swiss-Prot |
ENSRNOT00000090162.2 | UniProtKB/TrEMBL | |
ENSRNOT00000095155.1 | UniProtKB/TrEMBL | |
ENSRNOT00000098011.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | Phosphorylase Kinase, domain 1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Transferase(Phosphotransferase) domain 1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
InterPro | Kinase-like_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Prot_kinase_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Protein_kinase_ATP_BS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Ser-Thr/Tyr_kinase_cat_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Ser/Thr_kinase_AS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:360850 | UniProtKB/Swiss-Prot |
NCBI Gene | 360850 | ENTREZGENE |
PANTHER | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SERINE/THREONINE-PROTEIN KINASE NEK7 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Pkinase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Nek7 | PhenoGen |
PIRSF | Integrin-linked_kinase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PRINTS | TYRKINASE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROSITE | PROTEIN_KINASE_ATP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROTEIN_KINASE_DOM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PROTEIN_KINASE_ST | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000000657 | RatGTEx |
ENSRNOG00055000899 | RatGTEx | |
ENSRNOG00060004647 | RatGTEx | |
ENSRNOG00065021005 | RatGTEx | |
SMART | S_TKc | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | SSF56112 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A0G2JUP0 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6A625_RAT | UniProtKB/TrEMBL | |
A0A8I6AKB8 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZBE5 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2012-11-21 | Nek7 | NIMA-related kinase 7 | Nek7 | NIMA (never in mitosis gene a)-related kinase 7 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-10-23 | Nek7 | NIMA (never in mitosis gene a)-related kinase 7 | Nek7 | NIMA (never in mitosis gene a)-related expressed kinase 7 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-03-06 | Nek7 | NIMA (never in mitosis gene a)-related expressed kinase 7 | Nek7_predicted | NIMA (never in mitosis gene a)-related expressed kinase 7 (predicted) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-01-12 | Nek7_predicted | NIMA (never in mitosis gene a)-related expressed kinase 7 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |