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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dtwd1 | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of DTWD1 mRNA | CTD | PMID:17351261 | Dtwd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Dtwd1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to DTWD1 promoter] | CTD | PMID:19654925 | Dtwd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DTWD1 mRNA | CTD | PMID:32109520|PMID:33387578 | Dtwd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DTWD1 mRNA | CTD | PMID:21570461 | Dtwd1 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of DTWD1 mRNA | CTD | PMID:21346803 | Dtwd1 | Rat | 2-methylcholine | affects expression | ISO | DTWD1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of DTWD1 mRNA | CTD | PMID:21179406 | Dtwd1 | Rat | 5-fluorouracil | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Fluorouracil results in increased expression of DTWD1 mRNA | CTD | PMID:33770205 | Dtwd1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of DTWD1 mRNA | CTD | PMID:30047161 | Dtwd1 | Rat | acrolein | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Dtwd1 | Rat | acrylamide | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of DTWD1 mRNA | CTD | PMID:32763439 | Dtwd1 | Rat | aflatoxin B1 | decreases methylation | ISO | DTWD1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of DTWD1 gene | CTD | PMID:27153756 | Dtwd1 | Rat | aflatoxin M1 | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of DTWD1 mRNA | CTD | PMID:30928695 | Dtwd1 | Rat | all-trans-retinoic acid | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DTWD1 mRNA | CTD | PMID:33167477 | Dtwd1 | Rat | alpha-pinene | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Dtwd1 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of DTWD1 mRNA | CTD | PMID:30047161 | Dtwd1 | Rat | arsenite(3-) | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to DTWD1 mRNA] | CTD | PMID:32406909 | Dtwd1 | Rat | benzo[a]pyrene | multiple interactions | ISO | Dtwd1 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of DTWD1 mRNA] | CTD | PMID:22228805 | Dtwd1 | Rat | benzo[a]pyrene | increases expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of DTWD1 mRNA | CTD | PMID:22228805 | Dtwd1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DTWD1 mRNA | CTD | PMID:25181051 | Dtwd1 | Rat | bisphenol A | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of DTWD1 gene | CTD | PMID:31601247 | Dtwd1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DTWD1 mRNA | CTD | PMID:30816183 | Dtwd1 | Rat | butyric acid | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Butyric Acid results in decreased expression of DTWD1 mRNA | CTD | PMID:33770205 | Dtwd1 | Rat | cadmium dichloride | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of DTWD1 mRNA | CTD | PMID:38568856 | Dtwd1 | Rat | calcitriol | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of DTWD1 mRNA | CTD | PMID:16002434 | Dtwd1 | Rat | camptothecin | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Camptothecin results in increased expression of DTWD1 mRNA | CTD | PMID:33770205 | Dtwd1 | Rat | cisplatin | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of DTWD1 mRNA | CTD | PMID:27392435 | Dtwd1 | Rat | copper(II) sulfate | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of DTWD1 mRNA | CTD | PMID:19549813 | Dtwd1 | Rat | cyclosporin A | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DTWD1 mRNA | CTD | PMID:27989131 | Dtwd1 | Rat | dibutyl phthalate | decreases expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of DTWD1 mRNA | CTD | PMID:21266533 | Dtwd1 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of DTWD1 mRNA | CTD | PMID:21266533 | Dtwd1 | Rat | dicrotophos | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of DTWD1 mRNA | CTD | PMID:28302478 | Dtwd1 | Rat | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of DTWD1 mRNA | CTD | PMID:36653537 | Dtwd1 | Rat | dioxygen | decreases expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Oxygen deficiency results in decreased expression of DTWD1 mRNA | CTD | PMID:22629407 | Dtwd1 | Rat | dioxygen | multiple interactions | ISO | Dtwd1 (Mus musculus) | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in decreased expression of DTWD1 mRNA] | CTD | PMID:22629407 | Dtwd1 | Rat | dorsomorphin | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Dtwd1 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of DTWD1 mRNA | CTD | PMID:29391264 | Dtwd1 | Rat | ethanol | increases expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Ethanol results in increased expression of DTWD1 mRNA | CTD | PMID:30319688 | Dtwd1 | Rat | ethanol | affects expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Ethanol affects the expression of DTWD1 mRNA | CTD | PMID:30319688 | Dtwd1 | Rat | ethyl methanesulfonate | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of DTWD1 mRNA | CTD | PMID:23649840 | Dtwd1 | Rat | formaldehyde | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of DTWD1 mRNA | CTD | PMID:23649840 | Dtwd1 | Rat | fulvestrant | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of DTWD1 gene | CTD | PMID:31601247 | Dtwd1 | Rat | Garcinol | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | garcinol results in increased expression of DTWD1 mRNA | CTD | PMID:33770205 | Dtwd1 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of DTWD1 mRNA | CTD | PMID:33387578 | Dtwd1 | Rat | lead diacetate | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | lead acetate results in decreased expression of DTWD1 mRNA | CTD | PMID:38568856 | Dtwd1 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of DTWD1 mRNA | CTD | PMID:30047161 | Dtwd1 | Rat | methyl methanesulfonate | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of DTWD1 mRNA | CTD | PMID:23649840 | Dtwd1 | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of DTWD1 mRNA | CTD | PMID:38685446 | Dtwd1 | Rat | nickel atom | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of DTWD1 mRNA | CTD | PMID:25583101 | Dtwd1 | Rat | ozone | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of more ... | CTD | PMID:32699268 | Dtwd1 | Rat | panobinostat | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Panobinostat results in decreased expression of DTWD1 mRNA | CTD | PMID:33770205 | Dtwd1 | Rat | paracetamol | affects expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of DTWD1 mRNA | CTD | PMID:17562736 | Dtwd1 | Rat | paracetamol | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of DTWD1 mRNA | CTD | PMID:21420995 | Dtwd1 | Rat | pentachlorophenol | increases expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of DTWD1 mRNA | CTD | PMID:23892564 | Dtwd1 | Rat | phenylmercury acetate | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of DTWD1 mRNA | CTD | PMID:26272509 | Dtwd1 | Rat | phenylmercury acetate | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Dtwd1 | Rat | pirinixic acid | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Dtwd1 | Rat | pomalidomide | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | pomalidomide results in increased degradation of and results in decreased expression of DTWD1 protein | CTD | PMID:30067223 | Dtwd1 | Rat | quercetin | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of DTWD1 mRNA | CTD | PMID:21632981 | Dtwd1 | Rat | quercitrin | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | quercitrin results in decreased expression of DTWD1 mRNA | CTD | PMID:25193878 | Dtwd1 | Rat | SB 431542 | multiple interactions | ISO | DTWD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Dtwd1 | Rat | silver atom | decreases expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Silver results in decreased expression of DTWD1 mRNA | CTD | PMID:27131904 | Dtwd1 | Rat | silver(0) | decreases expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Silver results in decreased expression of DTWD1 mRNA | CTD | PMID:27131904 | Dtwd1 | Rat | sodium arsenite | increases stability | ISO | DTWD1 (Homo sapiens) | 6480464 | sodium arsenite results in increased stability of DTWD1 mRNA | CTD | PMID:25493608 | Dtwd1 | Rat | sodium arsenite | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of DTWD1 mRNA | CTD | PMID:38568856 | Dtwd1 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of DTWD1 mRNA | CTD | PMID:19281266 | Dtwd1 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of DTWD1 mRNA | CTD | PMID:30047161 | Dtwd1 | Rat | temozolomide | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of DTWD1 mRNA | CTD | PMID:31758290 | Dtwd1 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of DTWD1 mRNA | CTD | PMID:34492290 | Dtwd1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of DTWD1 mRNA | CTD | PMID:33387578 | Dtwd1 | Rat | trichostatin A | affects expression | ISO | DTWD1 (Homo sapiens) | 6480464 | trichostatin A affects the expression of DTWD1 mRNA | CTD | PMID:28542535 | Dtwd1 | Rat | triphenyl phosphate | affects expression | ISO | DTWD1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of DTWD1 mRNA | CTD | PMID:37042841 | Dtwd1 | Rat | triptonide | increases expression | ISO | Dtwd1 (Mus musculus) | 6480464 | triptonide results in increased expression of DTWD1 mRNA | CTD | PMID:33045310 | Dtwd1 | Rat | urethane | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of DTWD1 mRNA | CTD | PMID:28818685 | Dtwd1 | Rat | valproic acid | decreases expression | ISO | Dtwd1 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of DTWD1 mRNA | CTD | PMID:21427059 | Dtwd1 | Rat | valproic acid | decreases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DTWD1 mRNA | CTD | PMID:23179753 | Dtwd1 | Rat | valproic acid | affects expression | ISO | DTWD1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DTWD1 mRNA | CTD | PMID:25979313 | Dtwd1 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of DTWD1 mRNA | CTD | PMID:23034163 | Dtwd1 | Rat | vorinostat | increases expression | ISO | DTWD1 (Homo sapiens) | 6480464 | vorinostat results in increased expression of DTWD1 mRNA | CTD | PMID:27188386 | |