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Gene: Utp15 (UTP15, small subunit processome component) Rattus norvegicus

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Symbol:

Utp15

Name:

UTP15, small subunit processome component

RGD ID:

1310992

Description:

Predicted to be involved in positive regulation of RNA metabolic process and ribosome biogenesis. Predicted to be located in endoplasmic reticulum and fibrillar center. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human UTP15 (UTP15 small subunit processome component); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC310019; RGD1310992; similar to hypothetical protein FLJ12787; U3 small nucleolar RNA-associated protein 15 homolog; UTP15 SSU processome component; UTP15, U3 small nucleolar ribonucleoprotein, homolog; UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae); UTP15, U3 small nucleolar ribonucleoprotein, homolog (yeast)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UTP15 (UTP15 small subunit processome component)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Utp15 (UTP15 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Utp15 (UTP15 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UTP15 (UTP15 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UTP15 (UTP15 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Utp15 (UTP15 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UTP15 (UTP15 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UTP15 (UTP15 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Utp15 (UTP15 small subunit processome component)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	UTP15 (UTP15 small subunit processome component)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Utp15 (UTP15 small subunit processome component)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	utp15 (UTP15 small subunit processome component)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3071	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	UTP15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y23H5B.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	Y23H5B.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	utp15	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	31,329,222 - 31,347,022 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	31,329,223 - 31,347,046 (-)	Ensembl				GRCr8
mRatBN7.2	2	29,594,405 - 29,612,819 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	29,594,941 - 29,612,773 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	36,653,455 - 36,669,889 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	34,747,808 - 34,764,242 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	29,565,685 - 29,582,127 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	28,351,925 - 28,370,315 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	28,353,854 - 28,370,261 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	47,453,635 - 47,472,141 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	28,837,115 - 28,853,532 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	25,634,575 - 25,651,001 (-)	NCBI		Celera
RGSC_v3.1	2	28,758,349 - 28,771,165 (-)	NCBI
Cytogenetic Map	2	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

choline (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

deoxynivalenol (ISO)

dexamethasone (ISO)

dicrotophos (ISO)

diethylstilbestrol (ISO)

dioxygen (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

indometacin (ISO)

L-methionine (ISO)

leflunomide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

Nivalenol (ISO)

paraquat (EXP)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

potassium dichromate (ISO)

quercetin (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tetrachloromethane (EXP)

theophylline (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

troglitazone (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of rRNA processing (IEA,ISO)

positive regulation of transcription by RNA polymerase I (IBA,IEA,ISO)

ribosomal small subunit biogenesis (IEA,ISO,ISS)

rRNA processing (IBA,IEA)

Cellular Component

cytoplasm (IEA,ISO)

endoplasmic reticulum (IEA,ISO)

fibrillar center (IEA,ISO,ISS)

nucleolus (IBA,IEA,ISO,ISS)

nucleus (IEA)

small-subunit processome (IEA,ISO,ISS)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ribosome biogenesis pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:17699751	PMID:22658674	PMID:22681889	PMID:24219289

Genomics

Comparative Map Data

Utp15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	31,329,222 - 31,347,022 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	31,329,223 - 31,347,046 (-)	Ensembl				GRCr8
mRatBN7.2	2	29,594,405 - 29,612,819 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	29,594,941 - 29,612,773 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	36,653,455 - 36,669,889 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	34,747,808 - 34,764,242 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	29,565,685 - 29,582,127 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	28,351,925 - 28,370,315 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	28,353,854 - 28,370,261 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	47,453,635 - 47,472,141 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	28,837,115 - 28,853,532 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	25,634,575 - 25,651,001 (-)	NCBI		Celera
RGSC_v3.1	2	28,758,349 - 28,771,165 (-)	NCBI
Cytogenetic Map	2	q12	NCBI

UTP15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	73,565,741 - 73,583,380 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	73,565,443 - 73,583,380 (+)	Ensembl			hg38	GRCh38
GRCh37	5	72,861,566 - 72,879,205 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	72,897,354 - 72,913,550 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	5	68,756,885 - 68,773,081 (+)	NCBI		Celera
Cytogenetic Map	5	q13.2	NCBI
HuRef	5	68,067,100 - 68,083,293 (+)	NCBI		HuRef
CHM1_1	5	72,294,331 - 72,310,527 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	74,047,053 - 74,064,689 (+)	NCBI		T2T-CHM13v2.0

Utp15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	98,383,353 - 98,399,500 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	98,383,353 - 98,399,549 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	98,246,845 - 98,262,992 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	98,246,845 - 98,263,041 (-)	Ensembl			mm10	GRCm38
MGSCv37	13	99,016,800 - 99,032,947 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	99,347,002 - 99,363,149 (-)	NCBI		MGSCv36	mm8
Celera	13	101,897,013 - 101,913,154 (-)	NCBI		Celera
Cytogenetic Map	13	D1	NCBI
cM Map	13	51.87	NCBI

Utp15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	27,017,817 - 27,035,431 (-)	Ensembl
ChiLan1.0	NW_004955425	27,018,938 - 27,035,715 (-)	NCBI	ChiLan1.0	ChiLan1.0

UTP15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	41,738,496 - 41,754,457 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	39,892,130 - 39,908,057 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	41,735,713 - 41,753,026 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	42,336,817 - 42,351,574 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	42,337,245 - 42,349,974 (-)	Ensembl			panPan2	panpan1.1

UTP15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	56,378,116 - 56,395,009 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	56,381,734 - 56,393,813 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	53,354,396 - 53,372,975 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	56,900,377 - 56,918,895 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	56,900,404 - 56,918,891 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	53,960,779 - 53,979,333 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	54,728,707 - 54,747,412 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	55,620,047 - 55,638,574 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Utp15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	187,835,539 - 187,848,932 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936549	3,011,513 - 3,020,266 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936549	3,010,676 - 3,023,362 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UTP15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	82,715,416 - 82,734,113 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	82,715,411 - 82,733,042 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	84,210,698 - 84,227,058 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UTP15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	67,928,440 - 67,942,820 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	67,929,900 - 67,943,970 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666049	16,698,570 - 16,713,041 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Utp15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624924	1,435,938 - 1,453,704 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624924	1,435,240 - 1,456,193 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Utp15
166 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	587
Count of miRNA genes:	279
Interacting mature miRNAs:	357
Transcripts:	ENSRNOT00000022259
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	13325041	58325041	Rat
7387318	Stl32	Serum triglyceride level QTL 32	3.2	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	24117813	69117813	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
738010	Lnnr3	Liver neoplastic nodule remodeling QTL 3	2.94		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	2	1	42977529	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
9590080	Insglur4	Insulin/glucose ratio QTL 4	28.7	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	2	6152767	51152767	Rat
1579916	Bp270	Blood pressure QTL 270		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	16051883	61051883	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	22038044	67038044	Rat
731166	Mamtr2	Mammary tumor resistance QTL 2		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	9623581	54623581	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	27148328	145807373	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	28889991	73889991	Rat
1331764	Bp205	Blood pressure QTL 205	3.476		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	14368707	59368707	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1600379	Mcs18	Mammary carcinoma susceptibility QTL 18	2.6		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	9623581	44538110	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	7605533	104774005	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	83465677	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	5736325	50736325	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	28652666	139067443	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	18227137	63227137	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	73652666	Rat

Markers in Region

BF396985

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	29,595,000 - 29,595,129 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	28,352,521 - 28,352,649	NCBI	Rnor6.0
Rnor_5.0	2	47,453,692 - 47,453,820	UniSTS	Rnor5.0
RGSC_v3.4	2	28,835,791 - 28,835,919	UniSTS	RGSC3.4
Celera	2	25,633,251 - 25,633,379	UniSTS
RH 3.4 Map	2	34.5	UniSTS
Cytogenetic Map	2	q12	UniSTS

RH140112

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	29,596,385 - 29,596,603 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	28,353,906 - 28,354,123	NCBI	Rnor6.0
Rnor_5.0	2	47,455,077 - 47,455,294	UniSTS	Rnor5.0
RGSC_v3.4	2	28,837,176 - 28,837,393	UniSTS	RGSC3.4
Celera	2	25,634,636 - 25,634,853	UniSTS
Cytogenetic Map	2	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281718	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC098799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC107908	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC131851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022259 ⟹ ENSRNOP00000022259

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	29,596,569 - 29,612,773 (-)	Ensembl
Rnor_6.0 Ensembl	2	28,353,854 - 28,370,261 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097680 ⟹ ENSRNOP00000095293

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	31,329,223 - 31,347,046 (-)	Ensembl
mRatBN7.2 Ensembl	2	29,594,941 - 29,609,858 (-)	Ensembl

RefSeq Acc Id:

NM_001107647 ⟹ NP_001101117

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	31,330,579 - 31,346,995 (-)	NCBI
mRatBN7.2	2	29,596,325 - 29,612,741 (-)	NCBI
Rnor_6.0	2	28,353,845 - 28,370,261 (-)	NCBI
Rnor_5.0	2	47,453,635 - 47,472,141 (-)	NCBI
RGSC_v3.4	2	28,837,115 - 28,853,532 (-)	RGD
Celera	2	25,634,575 - 25,651,001 (-)	RGD

Sequence:

show sequence

GTGATTTTGAGCGAGTGCTTCTGAGTGGTCTGCTGTAGGGAGCTGGCGAAGTCTGGGGAGTCGT
CCTGGGGATCGGGGTGCCTCGGCGGACCCTCGGTGCCCCGCGGAGACCCAGAGCAGAATCACTG
CTATTCTTTAGCTCCAGACTACTGACTCCCGTCCAAAAGTGCACTTGCATGAAACCATGGCTGG
TTATAAACCTGTAGTGATTCAGACATATCCTGTACTTGGTGAGAAAATCACCCAAGACACTCTG
TACTGGAACAACTATAAGACCCCTGTTCAGATTAAGGAATTTGGTGCAGTGTCCAAAGTAGACT
TTTCTCCTCAGCCTCCATATAACTATGCCGTCACAGCTTCTTCAAGGATCCACATTTATGGCCG
GTACTCTCAAGAGCCTGTAAAAACCTTTTCCCGCTTTAAGGACACAGCATACTGTGCTACTTTT
CGTCAGGATGGTCAGTTGCTTGTCGCTGGCAGTGAAGATGGCGTGGTTCAACTTTTTGATATTA
GTGGGAGGGCTCCCCTCAGGCAATTTGAAGGCCACACAAAAGCGGTTCATACAGTAGATTTTAC
AGCTGACAAATATCACGTGGTCTCTGGAGCCGATGACTATACTGTTAAATTATGGGATATTCCA
AACTCCAAAGAAATTCTGACATTCAAAGAACATTCTGACTATGTGAGGTGTGGCTGTGCTAGCA
AACTGAACCCAGACCTTTTTGTAACAGGATCATATGATCATACCGTGAAGATGTTTGATGCCCG
GACAAATAAAAATGTTCTCTGTGTGGAGCATGGGCAGCCTGTGGAGAGTGTCCTCCTTTTCCCC
TCTGGAGGGCTTCTGGTGTCTGCAGGAGGCCGCTACGTTAAAGTCTGGGACATGTTAAAAGGCG
GGCAGCTGCTTGTTTCTTTGAAAAATCATCACAAGACGGTGACGTGTTTATGTCTGAGCAGCTC
TGGACAGAGGTTACTTTCCGGCTCACTGGACAGGAAAGTCAAAATCTACAGCACCACTTCCTAC
AAAGTCGTCCACAGCTTTGACTATGCAGCCTCAATCTTGAGTCTGGCGCTTTCTCATCAAGATG
AGACGGTTGTTGTAGGAATGACCAATGGAATACTGAGCGTTAAACACCGGAAGTCTGAAGCAAA
GAAGGAGTCTCTTCCCAGGAGAAGGAGGCCTGCATATCGAACCTTTATTAAAGGAAAAATTTAC
ACGAAGCAACGGGATGACATTGTGGTCACTAGGCCAGCGAAGAAGCACCTAGAGTGGTATGACA
GGGATCTGAAAAGTTTTCGGATCTCAAAGGCCCTCGACAGAGTCCTCGAGCCTAACTGTGTGAT
AAAGACCCCTGAGGTTACAGTTTCCATCATAAAGGAACTGAATCGGAGAGGCGTCCTTGCCAAC
GCTCTTGCAGGTCGGGACGAGAAGGAGATTACCCGGGTCCTTAACTTTTTGATAAGGAATCTGT
CTCAGCCAAGATTTGCCCCCGTTTTGATTAACGCTGCTGAAATAATCATTGATATATATTTACC
TGTAATTGGCCAGTCATCAGTAGTCGATAAAAAGTTTATAGTACTTCAAGGACTCGTAGAAAAA
GAAATCGATTACCAAAGAGAACTCCTAGAAACCTTGGGGATGATGGACATGCTGTTTGCTACCA
TGACACGGAATGGCAGCGCCCCTGTGTGGGAGCACGTGCCTGCTGAACTCCCAGAGGAGAAGAC
AGAGTCACCGAGGCAGCCCAGTGACACAGACAAGAACTCCTAACGGGAATTGTGTGACTGAATT
ACCAGGAAGAGGGCGGCTTCAGTACATTCAAAAGGATGATTGACAGAAGTTTGATGGAAGAGAC
TGGATTAACTAAAATTGGGGCATAAGTATCTGTTTCAAGATGTGGTTTTCCATGTATTGATTTC
TCTTATTTTGTATCGAAGACCTTAGTTGTCTCGGTCACAGTGTCTGTTGACCTTGGATGAATTG
ATACTGACCTTAATGGAGCCAAAACCTCAGTTGCTGTGGGGCCTTGTGGCCCTCTGGAGAGGTT
TCCAAGCGGAGTCCTGCCAAGAGAACAACCTTGGTTTTGTGCTTTCTGCTTTTAGCCTGGGAAA
TATCAAGAACAGCAATAAGGAAACATCCTTCTCTGTCCTCCCTGCCCCGGGGAGCCTCGCCCTA
CCCGCTTGCTGGTGTCTTCGAAGTGTTGAGTCAAGTGCTTTCATCAGCTGCTTGTGGGACTGTC
TTGTAAGTGTGGCACAACACTGGATATTGCCCCTGGAAGTGTGTTTAGGGTGTGATGAGTCTGT
TTTGTCACCCCCAAATTGTGCCCATCACCAGTGTTTTCTTTAGCCTGGCCTATCCAGAGAGAAC
TGACTGAACCAGTTCCCGCCCCTCAGCCTGCTGCCTCCCTTCCGTCTTCACGGTGCTTCAGCTG
TCCTCTCCTCTATTGTGAAGGCCTTTTAGCTTGCACCTGTGTCTTAGAGTGTATCTGTATGTGT
AACCCTTTGTAACAATTCTCTTTCTCTGCTTAACACTTCTTCTCTGTTCTTCATTTTGTAGGTC
AGATCAAACAGCAGCCAGTTTGTTTTGAAAATTTGTTTTTGAAAGTTCATTGTAAATTATATTT
TTTTATAAAGACAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039102170 ⟹ XP_038958098

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	31,329,222 - 31,347,022 (-)	NCBI
mRatBN7.2	2	29,594,405 - 29,612,819 (-)	NCBI

RefSeq Acc Id:

XM_063281718 ⟹ XP_063137788

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	31,329,222 - 31,347,022 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101117	(Get FASTA)	NCBI Sequence Viewer
	XP_038958098	(Get FASTA)	NCBI Sequence Viewer
	XP_063137788	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	A2RRU3	(Get FASTA)	NCBI Sequence Viewer
	AAI07909	(Get FASTA)	NCBI Sequence Viewer
	AAI31852	(Get FASTA)	NCBI Sequence Viewer
	EDM10143	(Get FASTA)	NCBI Sequence Viewer
	EDM10144	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022259.5
	ENSRNOP00000095293

RefSeq Acc Id:

NP_001101117 ⟸ NM_001107647

- UniProtKB:

A2RRU3 (UniProtKB/Swiss-Prot), A6I536 (UniProtKB/TrEMBL), A0A8I6B2C6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGYKPVVIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHI
YGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTV
DFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKMF
DARTNKNVLCVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCL
SSSGQRLLSGSLDRKVKIYSTTSYKVVHSFDYAASILSLALSHQDETVVVGMTNGILSVKHRKS
EAKKESLPRRRRPAYRTFIKGKIYTKQRDDIVVTRPAKKHLEWYDRDLKSFRISKALDRVLEPN
CVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIIIDI
YLPVIGQSSVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMTRNGSAPVWEHVPAELPE
EKTESPRQPSDTDKNS

hide sequence

Ensembl Acc Id:

ENSRNOP00000022259 ⟸ ENSRNOT00000022259

RefSeq Acc Id:	XP_038958098 ⟸ XM_039102170
- Peptide Label:	isoform X1
- UniProtKB:	A2RRU3 (UniProtKB/Swiss-Prot), A6I536 (UniProtKB/TrEMBL), A0A8I6B2C6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000095293 ⟸ ENSRNOT00000097680

RefSeq Acc Id:	XP_063137788 ⟸ XM_063281718
- Peptide Label:	isoform X1
- UniProtKB:	A2RRU3 (UniProtKB/Swiss-Prot), A6I536 (UniProtKB/TrEMBL), A0A8I6B2C6 (UniProtKB/TrEMBL)

Protein Domains

U3 small nucleolar RNA-associated protein 15 C-

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A2RRU3-F1-model_v2	AlphaFold	A2RRU3	1-528	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691089

Promoter ID:

EPDNEW_R1614

Type:

initiation region

Name:

Utp15_1

Description:

UTP15, small subunit processome component

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	28,370,287 - 28,370,347	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310992	AgrOrtholog
BioCyc Gene	G2FUF-54732	BioCyc
Ensembl Genes	ENSRNOG00000016591	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000022259.8	UniProtKB/Swiss-Prot
	ENSRNOT00000097680	ENTREZGENE
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7189311	IMAGE-MGC_LOAD
	IMAGE:7454138	IMAGE-MGC_LOAD
InterPro	U3_snoRNA-assocProt_15_C	UniProtKB/Swiss-Prot
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot
	WD40_repeat	UniProtKB/Swiss-Prot
	WD40_repeat_CS	UniProtKB/Swiss-Prot
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:310019	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:125224	IMAGE-MGC_LOAD
	MGC:156811	IMAGE-MGC_LOAD
NCBI Gene	310019	ENTREZGENE
PANTHER	U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG	UniProtKB/Swiss-Prot
	UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER	UniProtKB/Swiss-Prot
Pfam	UTP15_C	UniProtKB/Swiss-Prot
	WD40	UniProtKB/Swiss-Prot
PhenoGen	Utp15	PhenoGen
PROSITE	WD_REPEATS_1	UniProtKB/Swiss-Prot
	WD_REPEATS_2	UniProtKB/Swiss-Prot
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000016591	RatGTEx
SMART	WD40	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot
UniProt	A0A8I6B2C6	ENTREZGENE, UniProtKB/TrEMBL
	A2RRU3	ENTREZGENE
	A6I536	ENTREZGENE, UniProtKB/TrEMBL
	Q32Q03_RAT	UniProtKB/TrEMBL
	UTP15_RAT	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-01	Utp15	UTP15, small subunit processome component	Utp15	UTP15 SSU processome component	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-03	Utp15	UTP15 SSU processome component	Utp15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-23	Utp15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)	Utp15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (yeast)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-27	Utp15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (yeast)	RGD1310992	similar to hypothetical protein FLJ12787	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1310992	similar to hypothetical protein FLJ12787	RGD1310992_predicted	similar to hypothetical protein FLJ12787 (predicted)	Symbol and Name status set to approved	1299863	APPROVED
2005-01-20	RGD1310992_predicted	similar to hypothetical protein FLJ12787 (predicted)	LOC310019_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC310019_predicted	similar to hypothetical protein FLJ12787 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)