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Gene: Ebf2 (EBF transcription factor 2) Rattus norvegicus

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Symbol:

Ebf2

Name:

EBF transcription factor 2

RGD ID:

1310805

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including adipose tissue development; brown fat cell differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human EBF2 (EBF transcription factor 2); INTERACTS WITH (S)-nicotine; atrazine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

early B-cell factor 2; LOC361060; transcription factor COE2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EBF2 (EBF transcription factor 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ebf2 (early B cell factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ebf2 (EBF transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EBF2 (EBF transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EBF2 (EBF transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ebf2 (EBF transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EBF2 (EBF transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EBF2 (EBF transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ebf2 (EBF transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	EBF3 (EBF transcription factor 3)	HGNC	OrthoDB
Homo sapiens (human):	EBF1 (EBF transcription factor 1)	HGNC	OrthoDB
Homo sapiens (human):	EBF4 (EBF family member 4)	HGNC	OrthoDB
Homo sapiens (human):	HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	EBF2 (EBF transcription factor 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ebf2 (early B cell factor 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ebf2 (EBF transcription factor 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	ebf2 (EBF transcription factor 2)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	kn	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	unc-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	unc-3	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ebf2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	45,610,949 - 45,809,828 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	45,610,949 - 45,809,822 (+)	Ensembl				GRCr8
mRatBN7.2	15	41,435,509 - 41,634,403 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	41,435,509 - 41,634,403 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	43,300,099 - 43,499,091 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	44,450,328 - 44,649,316 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	42,895,757 - 43,094,640 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	43,905,099 - 44,103,742 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	43,905,099 - 44,103,742 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	47,492,258 - 47,690,729 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	46,779,220 - 46,977,125 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	41,100,921 - 41,298,980 (+)	NCBI		Celera
RGSC_v3.1	15	46,796,369 - 46,991,761 (+)	NCBI
Cytogenetic Map	15	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease type 2E (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (EXP)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,4,4'-trichlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

4-nonylphenol (ISO)

4-tert-Octylphenol (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzene (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

dicamba (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

fenvalerate (EXP)

folic acid (ISO)

glyphosate (EXP,ISO)

herbicide (ISO)

ivermectin (ISO)

L-methionine (ISO)

lead(0) (ISO)

lipopolysaccharide (ISO)

mercury dichloride (EXP)

nickel atom (ISO)

nicotine (EXP)

okadaic acid (ISO)

p-tert-Amylphenol (ISO)

PCB138 (ISO)

resveratrol (ISO)

sulforaphane (ISO)

tanespimycin (ISO)

titanium dioxide (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adipose tissue development (ISO)

brown fat cell differentiation (ISO)

cell fate determination (ISO)

positive regulation of cold-induced thermogenesis (ISO,ISS)

positive regulation of DNA-templated transcription (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IEA)

Molecular Function

chromatin binding (ISO)

DNA binding (IEA,ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	EBF2 promotes the recruitment of beige adipocytes in white adipose tissue.	Stine RR, etal., Mol Metab. 2015 Nov 14;5(1):57-65. doi: 10.1016/j.molmet.2015.11.001. eCollection 2016 Jan.

Additional References at PubMed

PMID:9211912	PMID:12139918	PMID:23499423

Genomics

Comparative Map Data

Ebf2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	45,610,949 - 45,809,828 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	45,610,949 - 45,809,822 (+)	Ensembl				GRCr8
mRatBN7.2	15	41,435,509 - 41,634,403 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	41,435,509 - 41,634,403 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	43,300,099 - 43,499,091 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	44,450,328 - 44,649,316 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	42,895,757 - 43,094,640 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	43,905,099 - 44,103,742 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	43,905,099 - 44,103,742 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	47,492,258 - 47,690,729 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	46,779,220 - 46,977,125 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	41,100,921 - 41,298,980 (+)	NCBI		Celera
RGSC_v3.1	15	46,796,369 - 46,991,761 (+)	NCBI
Cytogenetic Map	15	p12	NCBI

EBF2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	25,841,725 - 26,045,413 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	25,841,725 - 26,045,413 (-)	Ensembl			hg38	GRCh38
GRCh37	8	25,699,241 - 25,902,929 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	25,757,490 - 25,958,309 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	25,757,489 - 25,803,239	NCBI
Celera	8	24,663,002 - 24,864,217 (-)	NCBI		Celera
Cytogenetic Map	8	p21.2	NCBI
HuRef	8	24,243,986 - 24,447,881 (-)	NCBI		HuRef
CHM1_1	8	25,900,716 - 26,104,235 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	26,116,725 - 26,320,915 (-)	NCBI		T2T-CHM13v2.0

Ebf2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	67,470,741 - 67,668,401 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	67,470,741 - 67,668,367 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	67,233,292 - 67,430,952 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	67,233,292 - 67,430,918 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	67,852,129 - 68,048,604 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	66,187,402 - 66,383,877 (+)	NCBI		MGSCv36	mm8
Celera	14	64,988,821 - 65,184,707 (+)	NCBI		Celera
Cytogenetic Map	14	D1	NCBI
cM Map	14	34.63	NCBI

Ebf2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	48,671,777 - 48,859,874 (-)	Ensembl
ChiLan1.0	NW_004955403	48,674,218 - 48,859,843 (-)	NCBI	ChiLan1.0	ChiLan1.0

EBF2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	44,379,989 - 44,585,163 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	20,094,337 - 20,299,596 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	25,119,782 - 25,325,305 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	22,030,143 - 22,094,788 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	22,027,573 - 22,231,421 (-)	Ensembl			panPan2	panpan1.1
PanPan1.1 Ensembl	8	22,027,573 - 22,231,421 (-)	NCBI			panPan2	panpan1.1

EBF2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	31,478,361 - 31,671,018 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	31,478,349 - 31,668,555 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	32,065,662 - 32,257,085 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	31,678,367 - 31,870,138 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	31,678,348 - 31,870,632 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	31,635,136 - 31,826,469 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	31,483,350 - 31,674,342 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	31,650,661 - 31,842,117 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ebf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	9,526,814 - 9,701,965 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936757	780,041 - 954,021 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936757	779,529 - 954,409 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EBF2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	9,817,002 - 10,025,164 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	9,816,992 - 10,027,574 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	10,983,965 - 11,188,786 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EBF2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	23,949,496 - 24,160,949 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666052	18,000,296 - 18,201,495 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ebf2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	20,794,698 - 20,989,306 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624758	20,791,824 - 20,989,836 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Ebf2
516 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	353
Count of miRNA genes:	219
Interacting mature miRNAs:	275
Transcripts:	ENSRNOT00000016568
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331729	Rf42	Renal function QTL 42	3.071		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	15	17362897	73690657	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	42356671	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	306329	45306329	Rat
2293686	Bmd36	Bone mineral density QTL 36	7.4	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	15	33611058	71477291	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	12496141	65205939	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
2293691	Bmd37	Bone mineral density QTL 37	6.6	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	15	33611058	71477291	Rat
2293688	Bss29	Bone structure and strength QTL 29	5.31	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	15	11111142	56111142	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat
631273	Lecl2	Lens clarity QTL 2		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	15	10596089	55596089	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	40631268	98288169	Rat
2300167	Bmd63	Bone mineral density QTL 63	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
731170	Pur3	Proteinuria QTL 3	2.3	0.0005	urine protein amount (VT:0005160)	urine protein excretion rate (CMO:0000759)	15	1	41686771	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2266368	46921453	Rat
152025253	Hrtrt24	Heart rate QTL 24	3.82		heart pumping trait (VT:2000009)		15	27885774	86257085	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	22117933	67117933	Rat
2300173	Bmd62	Bone mineral density QTL 62	12.8	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	19856566	46187442	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	5530756	50530756	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	34054139	79054139	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
2306968	Anxrr23	Anxiety related response QTL 23	4.83		reflex trait (VT:0001961)	amplitude of the acoustic startle response (CMO:0001520)	15	40631268	46187442	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
7411725	Strs7	Sensitivity to stroke QTL 7	3.8		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	15	40289901	49308583	Rat

Markers in Region

BQ203388

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	41,632,639 - 41,632,856 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	44,101,979 - 44,102,195	NCBI	Rnor6.0
Rnor_5.0	15	47,493,805 - 47,494,021	UniSTS	Rnor5.0
RGSC_v3.4	15	46,975,362 - 46,975,578	UniSTS	RGSC3.4
Celera	15	41,297,217 - 41,297,433	UniSTS
RH 3.4 Map	15	329.71	UniSTS
Cytogenetic Map	15	p12	UniSTS

AU048465

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	41,450,450 - 41,450,551 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	43,919,967 - 43,920,067	NCBI	Rnor6.0
Rnor_5.0	15	47,675,761 - 47,675,861	UniSTS	Rnor5.0
RGSC_v3.4	15	46,794,162 - 46,794,262	UniSTS	RGSC3.4
Celera	15	41,115,854 - 41,115,954	UniSTS
Cytogenetic Map	15	p12	UniSTS

PMC134715P3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	41,631,685 - 41,631,777 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	44,101,025 - 44,101,116	NCBI	Rnor6.0
Rnor_5.0	15	47,494,884 - 47,494,975	UniSTS	Rnor5.0
RGSC_v3.4	15	46,974,408 - 46,974,499	UniSTS	RGSC3.4
Celera	15	41,296,263 - 41,296,354	UniSTS
Cytogenetic Map	15	p12	UniSTS

UniSTS:498231

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	41,632,113 - 41,632,515 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	44,101,453 - 44,101,854	NCBI	Rnor6.0
Rnor_5.0	15	47,494,146 - 47,494,547	UniSTS	Rnor5.0
RGSC_v3.4	15	46,974,836 - 46,975,237	UniSTS	RGSC3.4
Celera	15	41,296,691 - 41,297,092	UniSTS
Cytogenetic Map	15	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	12	65	136	59	58	27	27	27	6	224	125	11	115	55	88	31	12	12

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108383	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC132635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000016568 ⟹ ENSRNOP00000016568

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	45,610,949 - 45,809,822 (+)	Ensembl
mRatBN7.2 Ensembl	15	41,435,509 - 41,634,403 (+)	Ensembl
Rnor_6.0 Ensembl	15	43,905,099 - 44,103,742 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000173641 ⟹ ENSRNOP00000104492

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	45,610,949 - 45,807,047 (+)	Ensembl

RefSeq Acc Id:

NM_001108383 ⟹ NP_001101853

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	45,610,949 - 45,809,822 (+)	NCBI
mRatBN7.2	15	41,435,509 - 41,634,403 (+)	NCBI
Rnor_6.0	15	43,905,099 - 44,103,742 (+)	NCBI
Rnor_5.0	15	47,492,258 - 47,690,729 (-)	NCBI
RGSC_v3.4	15	46,779,220 - 46,977,125 (+)	RGD
Celera	15	41,100,921 - 41,298,980 (+)	RGD

Sequence:

show sequence

CTATGGAGAGTCGCAGTCTCTGAAAGCGCAAGCTTCCCCTTCGCTCGCCTAGCAAACCTGCACC
GCAGGCGCTGTATCCTCTAGCGGCTAACTCTCGTAGTTCTTCTGTGAGCGCTCACCTACAGCTA
GGGGGTCCGGTCAGGAGTCAATTGGCACTCAAACAAGAGCCCAGAGTAGAGAGGAGAGTCTCCC
GAATGTAATGATGCTGGGAGGCTCGGGTGCAGCCGCTCGAACCGCGGTGCAGCTGATTGTCTCC
TCTACGGCAGATGGTCTTTGAGCACAGATTTGCATTCATTGTCTTCAAATCTGTTTTCGCTCTG
GTGTTCTAGATTTCAGCAGCAGATCTACGCGCAGATCAGAATACAAAAAGAGAAGCGAGAAAAT
AACACCCAGCCAGGAGGATTTTTTTTTTTAATAGGCACCTCCAGCCGTCTAGGGTTTCAGCTAT
TTTGTGGAGCCGCTGCTTCCCGACCACCAACCTTCGTGACCACAGCGCATGGCGGACAAAGTTT
CCAGGACTTCTTCACAGACGCCTCGTGTCTCCTCCGCAGGGTTCCCCGGGCTTCAATGATTGGG
GAGGGAAGATAAAAAGGGGGGATTTGAAACTACACCCGCAGTTCTCAGCCAGCCACGCTGTCAG
CAACCTCTCCCATCTGCAAAGAACAGGTGATGCTTCTAAATTGTGGCCACTTTCTGGAGAACGC
TCTGCAGCTGGAAGGATGCGGGCGACCTAGAGTGGAAGCCCCGAGGCGACAGATCTGAAGCTAC
CGAGGATAAAAACGCAAAGTTTGCATTGTGCGTGGAGGAAAGGGCTGGCTATTTCTTTCCAGGA
GGGCCCCAAACTTCGGCCCTCTGCCGCTTTTCTCGGATTGCTTTGGAGAACACCATTTGCTGGC
AGCGCTGGAAAGTCGGGACGGTGTTGTCGTAAAGTCACTTTTAAGGCGACAGTAGAGGACTAGA
CTTTTTAAATGTTTGGGATTCAAGATACGCTAGGAAGAGGACCAGTTCTGAAAGAAAAGTCGCT
GGGTGCCGAGATGGATTCGGTCAGGTCCTGGGTCCGGAATGTCGGCGTGGTGGATGCCAATGTC
GCGGCTCAGAGTGGCGTTGCCCTGTCTCGGGCCCACTTTGAAAAGCAACCTCCTTCTAACTTGA
GGAAATCCAACTTCTTCCATTTTGTCCTGGCGCTCTACGACAGGCAGGGACAGCCGGTGGAGAT
TGAGCGCACAGCCTTCGTGGACTTTGTGGAGAATGACAAAGAGCAAGGCAACGAGAAAACCAAC
AATGGCACTCACTACAAGTTACAGCTCCTTTACAGCAATGGTGTCCGCACAGAGCAGGACCTCT
ATGTCAGGCTCATAGACTCAGTCACAAAACAGCCTATTGCCTATGAGGGACAGAATAAGAATCC
AGAAATGTGCAGAGTTCTGCTGACACACGAGGTGATGTGCAGCCGATGCTGCGAGAAAAAGAGC
TGTGGGAACCGGAATGAGACCCCGTCAGACCCCGTCATCATCGACAGATTCTTTTTAAAATTTT
TCCTGAAGTGCAATCAGAATTGTTTGAAAACAGCAGGAAACCCAAGGGACATGAGACGGTTTCA
GGTCGTGTTGTCTACAACGGTCAATGTGGATGGACATGTGCTGGCTGTTTCTGACAACATGTTT
GTTCATAACAACTCTAAGCATGGAAGGAGAGCGAGAAGGCTTGACCCATCAGAAGCTACACCCT
GCATCAAAGCCATCAGTCCAAGTGAAGGCTGGACCACGGGAGGGGCCATGGTCATCATCATTGG
TGACAACTTTTTTGATGGTCTCCAAGTTGTATTTGGTACCATGCTCGTATGGAGTGAGCTTATA
ACCCCTCATGCCATCAGAGTACAGACCCCTCCCCGGCATATCCCTGGAGTTGTGGAAGTGACAC
TATCTTATAAATCCAAACAGTTCTGCAAAGGAGCCCCAGGCAGGTTCATCTACACAGCCTTAAA
TGAACCCACCATAGACTATGGCTTCCAAAGACTGCAGAAAGTCATCCCAAGGCACCCAGGAGAC
CCTGAGAGGCTAGCTAAGGAAATGCTATTGAAAAGAGCTGCAGACCTGGTGGAAGCCCTCTACG
GCACACCCCACAATAACCAGGACATCATTTTAAAGCGTGCTGCAGACATTGCAGAAGCCCTGTA
CAGTGTCCCCCGGAACCCCAGCCAGATTCCAGCTCTCTCCAGCTCCCCAGCTCATAGCGGCATG
ATGGGTATCAACTCTTACGGCAGCCAGCTGGGGGTCAGCATTTCAGAGTCTACACAAGGAAATA
ACCAAGGATACATCCGCAACACAAGCAGCATCTCCCCTCGGGGATACTCCTCCAGCTCCACGCC
CCAGCAGTCTAATTACAGCACCTCCAGTAACAGCATGAATGGCTACAGCAACGTTCCTATGGCC
AACCTGGGTGTGCCAGGATCACCGGGTTTTCTGAACGGCTCACCTACAGGCTCCCCATATGGAA
TCATGTCTTCAAGCCCCACCGTGGGATCCTCCAGCACATCCTCCATCCTCCCGTTCTCCTCTTC
AGTTTTTCCTGCTGTCAAACAGAAGAGTGCCTTTGCCCCTGTCATCAGGCCCCAAGGCTCCCCT
TCGCCTGCCTGCTCCAGTGGCAATGGGAATGGATTCAGAGCCATGACGGGACTTGTTGTACCCC
CGATGTAAAGTAGAGGAAGAACTGCTTTCTCATAGCACAAAACTACTTATTCCAATGGACCAAT
TATGAAGGAAGCACTCTGAGCTTGTTGGGGAGACTTGCACCCCCAAGCGGCCATGTTGGACAGA
TTTGGGAAGGCAGAGAGCCGCCATCTTGGTCTCGTGTTCCTCATGAAGCATTGACAGTCACTAC
ACAAACTGACCCTTTTGGAGACAAGAACAGAGAAATGTCATTCTCTGACGTGGTCAGTGCTAAG
AGCAGAAACGCAATTCTTTGTTATGAACATTACGAAAACCACCTTCCTATGTTTGTAAAATATT
TAAGAAAAACATTGGCAAACATTCATGCTTAATATTTTGGATACTATTTGTTTTTCTTTGTAGG
AAAAAAGTTGAAAGTTTCTATTTTCTATGAATCCTTTCAGATACCAATTTAGTTTATGCAGAAA
AAAGTTGAACAAAACAGGGTACCAACATGGAAGACTTTCTTAAAATGAAACCTGAATTGAATGA
GGAAATGTTGTGTGTGTGTTTGCTTATACTTTAAGCTCTTTAAAAGAAAAAGGGAAAAAATTTT
AAATGTTTTACAGTTATTTAAATAAATAAACGTGTAACTTATTGTAAGTAGACGTAGAAATTAA
GACCTTTTTTAAGAAGAGAAGAATTCTCTTCCTGATGTAAAATGAAATTGACAACACGTAGTGA
CAAGTTTTAAAGGTGTGTTGCTTATTAGATTCTTATCCTACATCCCACACCCCCTCTTTGTCCA
TCATTTTATCCACCTATGCACAAGAACATGTAACTTGTGCAGATTCCCACAGAACAATCCACCA
CAGAAACCAGACTCAGATAAATGCCAGCACACCAACACTTCAGTCCACAACTTCATTCCCAGAT
CTGCTTTCTGGTTCACAAATCACTTGTGGTATCCACTCTTGGTAAAGCATTTTAAAAACTATAT
TCTTCCCTGAGGAAATGCAGGGAATCCCCACGTTACCATCTCAGCTTTGAACATTCCCAGGCAA
GAAGTATCTCACCTCTAGGAAGAGCCAAAGCCACACGGCTACACTGACCAAGGACTCCACAATT
TTCCTCCGACAGAGCGGTATAGTCCTTCCTCTTTGGGTACCTGATTCAGGTATGGCAGCAGGAA
GCTCCACAGAACTTTGCAGAAAGAGCTTGGGGAGGTTGCCTATGTTTCTTGGACTCTTAAGACT
CGGTCTTTGACTGCTTCCTTTCTAGGCAGTTTTCATTTTATGTTACTAAACTCCCCTGGAAAAG
CATGTATCTCACCTGACACTTGTTTCTGAGGTGAGTGGGATGGGGTGAAGAAGGAAGAACTTAA
AAATCCCTAAGCGGCTCTCCTACTGGGAGATTTGTGGCAGCTGTGTTCCAAGCCTGCCCCGGGA
GCCTTGTGCTACCTACCTAGTTCTTAGCAGGGAAACCTTTGCAGTAGTTGCTAACAGTGGTAGA
CTCTTGAAAATGTGTGGTCCTGGAGATGCATCTAGACTTGCTTGGCTTGCCAATAGGATGTCAT
GATTTTCCAGGTCAGGTGTCTTCTCTTTGCTTCCACTGACTTAGCTTGGGGTTCTTGGTTAGGC
TTCTAGCGTTGGATGCAGCTTTTGTGAAAAAAGCAAAACCATCATTAGTACTTCTGAGCCATTT
TAGATGACCCTCTCATTGCCCCTCTGATGTAGTCCTCCCCCAAACCCGCAACTGTCTTATTTGC
CTTCAGTTTGCTCTGGAGTTACCCAATACGACACTTTTTTCTATGCACATGAGAATCCACATTT
TTGAAACCTGGCATGCTCATAACTACTGCTGACAGTCCTCCACAGTCAGGGCTCACAGTGCCAA
AATATACGGAAATGCATGAGAGAAACTTCCCTGGCTAACAACATGGTACAGGGAACGGATGTGT
GGAATACGTAAATTACCATCCCAAAATGGAGGCAGACTACAATTAAGCATGTTTAGACCTGGCT
TTGAGCCAATCCAACCTAAGAATTTTCTTTCTTTCTTTCATTTTTTTTTTAAAGTAGCATAGCT
TTTAGAACCTGTGAATCTTTCTCTTGCATGAGGATTAGTGCAGTACTGTCTCCAGAATGATCGT
AGAATCTGTCAGTAGCTTTACACCGAAAACTGTGTGTAACTAAATACCAGACATCTTTGACCAT
TCACTAGGACATCAGCAGCCACAGATCTATTTAATTGTACAAACGTGTGTAAGGGTTATTTTTA
GTGTACTAATAAATTAAAAACAAAGCCACTCTGTCCTCTTTAGTCATTGCTATTAAATGATTCT
GGTCCCAGGTTGTTTTTGTGCTACTTGGCAGACAAGTATCTCTATAGGTAATGACAAAATTCTG
TTCTATTTTTGAGAGGAGCTGTGTAAGATTTTCATTTAAAGGGACAACTTACTGCATTATTTAT
CATATTTCTTTTGTTACAGCATCGAAATTCTTCCCAGTTTTTCTTTGCACATTTCAACATGCAT
GGTTTAAAAACCATTATCTTTACCTTTTGTACAGTAAGGTCTCATTTCCAAACTGTATAGTTTT
GTTGTTTTTGCTTTGTCAGTTACATACAGTATAAAGTTGCTATGCACAGAGCTTTTTGTAAAGA
CAGCTTTTTTTTGTTTACTGTTTTTAATGGTCTTCCTTATGAAAGAATATCTTGTTTGTAAAAT
GAATATGTCTACTTCAGTTTTAAACTTTAAATTATCCTAACAAAAAATAAAATTTTTGTACTG

hide sequence

RefSeq Acc Id:

XM_006252133 ⟹ XP_006252195

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	45,612,223 - 45,809,828 (+)	NCBI
mRatBN7.2	15	41,436,965 - 41,632,209 (+)	NCBI
Rnor_6.0	15	43,906,353 - 44,101,548 (+)	NCBI
Rnor_5.0	15	47,492,258 - 47,690,729 (-)	NCBI

Sequence:

show sequence

CCGGCCAATCCCGGGCGTCCATGCAAATGAGGCTCCTTATCGGGCCTCGGCTCCGCCTCCCGCG
GCCCGGGTTGTAGTAACCATTCATGGGGCCCGCGCGCTGCTGCAGCCGGGCTCTGCGGCTTGCT
CAACCACCGCCTCCTCCCGGCTCCGGGTCTTCCCCTCCATCTTACAACTAACTGATCCTGTTGG
GGATTTTTTTTTTCTATATCGGAACAGTGGGGAGGAGCAGGGAGGGGGGACAAGGAGGAAGGGG
AGAGATCAGGCAGCTATCTATCTCCTCCTGTTTTTCCCAGAACAGGTGATGCTTCTAAATTGTG
GCCACTTTCTGGAGAACGCTCTGCAGCTGGAAGGATGCGGGCGACCTAGAGTGGAAGCCCCGAG
GCGACAGATCTGAAGCTACCGAGGATAAAAACGCAAAGTTTGCATTGTGCGTGGAGGAAAGGGC
TGGCTATTTCTTTCCAGGAGGGCCCCAAACTTCGGCCCTCTGCCGCTTTTCTCGGATTGCTTTG
GAGAACACCATTTGCTGGCAGCGCTGGAAAGTCGGGACGGTGTTGTCGTAAAGTCACTTTTAAG
GCGACAGTAGAGGACTAGACTTTTTAAATGTTTGGGATTCAAGATACGCTAGGAAGAGGACCAG
TTCTGAAAGAAAAGTCGCTGGGTGCCGAGATGGATTCGGTCAGGTCCTGGGTCCGGAATGTCGG
CGTGGTGGATGCCAATGTCGCGGCTCAGAGTGGCGTTGCCCTGTCTCGGGCCCACTTTGAAAAG
CAACCTCCTTCTAACTTGAGGAAATCCAACTTCTTCCATTTTGTCCTGGCGCTCTACGACAGGC
AGGGACAGCCGGTGGAGATTGAGCGCACAGCCTTCGTGGACTTTGTGGAGAATGACAAAGAGCA
AGGCAACGAGAAAACCAACAATGGCACTCACTACAAGTTACAGCTCCTTTACAGCAATGGTGTC
CGCACAGAGCAGGACCTCTATGTCAGGCTCATAGACTCAGTCACAAAACAGCCTATTGCCTATG
AGGGACAGAATAAGAATCCAGAAATGTGCAGAGTTCTGCTGACACACGAGGTGATGTGCAGCCG
ATGCTGCGAGAAAAAGAGCTGTGGGAACCGGAATGAGACCCCGTCAGACCCCGTCATCATCGAC
AGATTCTTTTTAAAATTTTTCCTGAAGTGCAATCAGAATTGTTTGAAAACAGCAGGAAACCCAA
GGGACATGAGACGGTTTCAGGTCGTGTTGTCTACAACGGTCAATGTGGATGGACATGTGCTGGC
TGTTTCTGACAACATGTTTGTTCATAACAACTCTAAGCATGGAAGGAGAGCGAGAAGGCTTGAC
CCATCAGAAGCTACACCCTGCATCAAAGCCATCAGTCCAAGTGAAGGCTGGACCACGGGAGGGG
CCATGGTCATCATCATTGGTGACAACTTTTTTGATGGTCTCCAAGTTGTATTTGGTACCATGCT
CGTATGGAGTGAGCTTATAACCCCTCATGCCATCAGAGTACAGACCCCTCCCCGGCATATCCCT
GGAGTTGTGGAAGTGACACTATCTTATAAATCCAAACAGTTCTGCAAAGGAGCCCCAGGCAGGT
TCATCTACACAGCCTTAAATGAACCCACCATAGACTATGGCTTCCAAAGACTGCAGAAAGTCAT
CCCAAGGCACCCAGGAGACCCTGAGAGGCTAGCTAAGGAAATGCTATTGAAAAGAGCTGCAGAC
CTGGTGGAAGCCCTCTACGGCACACCCCACAATAACCAGGACATCATTTTAAAGCGTGCTGCAG
ACATTGCAGAAGCCCTGTACAGTGTCCCCCGGAACCCCAGCCAGATTCCAGCTCTCTCCAGCTC
CCCAGCTCATAGCGGCATGATGGGTATCAACTCTTACGGCAGCCAGCTGGGGGTCAGCATTTCA
GAGTCTACACAAGGAAATAACCAAGGATACATCCGCAACACAAGCAGCATCTCCCCTCGGGGAT
ACTCCTCCAGCTCCACGCCCCAGCAGTCTAATTACAGCACCTCCAGTAACAGCATGAATGGCTA
CAGCAACGTTCCTATGGCCAACCTGGGTGTGCCAGGATCACCGGGTTTTCTGAACGGCTCACCT
ACAGGCTCCCCATATGGAATCATGTCTTCAAGCCCCACCGTGGGATCCTCCAGCACATCCTCCA
TCCTCCCGTTCTCCTCTTCAGTTTTTCCTGCTGTCAAACAGAAGAGTGCCTTTGCCCCTGTCAT
CAGGCCCCAAGGCTCCCCTTCGCCTGCCTGCTCCAGTGGCAATGGGAATGGATTCAGAGCCATG
ACGGGACTTGTTGTACCCCCGATGTAAAGTAGAGGAAGAACTGCTTTCTCATAGCACAAAACTA
CTTATTCCAATGGACCAATTATGAAGGAAGCACTCTGAGCTTGTTGGGGAGACTTGCACCCCCA
AGCGGCCATGTTGGACAGATTTGGGAAGGCAGAGAGCCGCCATCTTGGTCTCGTGTTCCTCATG
AAGCATTGACAGTCACTACACAAACTGACCCTTTTGGAGACAAGAACAGAGAAATGTCATTCTC
TGACGTGGTCAGTGCTAAGAGCAGAAACGCAATTCTTTGTTATGAACATTACGAAAACCACCTT
CCTATGTTTGTAAAATATTTAAGAAAAACATTGGCAAACATTCATGCTTAATATTTTGGATACT
ATTTGTTTTTCTTTGTAGGAAAAAAGTTGAAAGTTTCTATTTTCTATGAATCCTTTCAGATACC
AATTTAGTTTATGCAGAAAAAAGTTGAACAAAACAGGGTACCAACATGGAAGACTTTCTTAAAA
TGAAACCTGAATTGAATGAGGAAATGTTGTGTGTGTGTTTGCTTATACTTTAAGCTCTTTAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101853	(Get FASTA)	NCBI Sequence Viewer
	NP_001418514	(Get FASTA)	NCBI Sequence Viewer
	NP_001418515	(Get FASTA)	NCBI Sequence Viewer
	XP_006252195	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL85404	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000016568
	ENSRNOP00000016568.4

RefSeq Acc Id:

NP_001101853 ⟸ NM_001108383

- UniProtKB:

D3ZT68 (UniProtKB/TrEMBL), A6K6P4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFGIQDTLGRGPVLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKS
NFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVR
LIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLK
CNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEATPCIK
AISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSY
KSKQFCKGAPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLAKEMLLKRAADLVEALYGTP
HNNQDIILKRAADIAEALYSVPRNPSQIPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQG
YIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMS
SSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPVIRPQGSPSPACSSGNGNGFRAMTGLVVPPM

hide sequence

RefSeq Acc Id:

XP_006252195 ⟸ XM_006252133

- Peptide Label:

isoform X1

- Sequence:

show sequence

MFGIQDTLGRGPVLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKS
NFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVR
LIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLK
CNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEATPCIK
AISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSY
KSKQFCKGAPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLAKEMLLKRAADLVEALYGTP
HNNQDIILKRAADIAEALYSVPRNPSQIPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQG
YIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMS
SSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPVIRPQGSPSPACSSGNGNGFRAMTGLVVPPM

hide sequence

Ensembl Acc Id:

ENSRNOP00000016568 ⟸ ENSRNOT00000016568

Ensembl Acc Id:

ENSRNOP00000104492 ⟸ ENSRNOT00000173641

Protein Domains

IPT/TIG

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZT68-F1-model_v2	AlphaFold	D3ZT68	1-575	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310805	AgrOrtholog
BioCyc Gene	G2FUF-13310	BioCyc
Ensembl Genes	ENSRNOG00000011548	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000016568	ENTREZGENE
	ENSRNOT00000016568.5	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.4280	UniProtKB/TrEMBL
	2.60.40.10	UniProtKB/TrEMBL
	2.60.40.3180	UniProtKB/TrEMBL
InterPro	COE_DBD	UniProtKB/TrEMBL
	COE_DBD_sf	UniProtKB/TrEMBL
	COE_HLH	UniProtKB/TrEMBL
	COE_IPT	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_E-set	UniProtKB/TrEMBL
	IPT_TIG_rcpt	UniProtKB/TrEMBL
	Transcription_factor_COE	UniProtKB/TrEMBL
	Transcription_factor_COE_CS	UniProtKB/TrEMBL
KEGG Report	rno:361060	UniProtKB/TrEMBL
NCBI Gene	361060	ENTREZGENE
PANTHER	TF_COE	UniProtKB/TrEMBL
Pfam	COE1_DBD	UniProtKB/TrEMBL
	COE1_HLH	UniProtKB/TrEMBL
	TIG	UniProtKB/TrEMBL
PhenoGen	Ebf2	PhenoGen
PROSITE	COE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000011548	RatGTEx
SMART	IPT	UniProtKB/TrEMBL
Superfamily-SCOP	Ig_E-set	UniProtKB/TrEMBL
UniProt	A6K6P4	ENTREZGENE, UniProtKB/TrEMBL
	D3ZT68	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-10-03	Ebf2	EBF transcription factor 2	Ebf2	early B-cell factor 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Ebf2	early B-cell factor 2	Ebf2_predicted	early B-cell factor 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Ebf2_predicted	early B-cell factor 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar