C13h1orf115 (similar to human chromosome 1 open reading frame 115) - Rat Genome Database

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Pathways
Gene: C13h1orf115 (similar to human chromosome 1 open reading frame 115) Rattus norvegicus
Analyze
Symbol: C13h1orf115
Name: similar to human chromosome 1 open reading frame 115
RGD ID: 1310587
Description: Predicted to be involved in regulation of response to drug. Predicted to be located in 9+0 non-motile cilium. Orthologous to human C1orf115 (chromosome 1 open reading frame 115); INTERACTS WITH (+)-schisandrin B; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC360894; LOC360894; required for drug-induced death protein 1; RGD1310587; similar to hypothetical protein FLJ14146; uncharacterized protein C1orf115 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81398,953,841 - 98,963,577 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1398,953,843 - 98,963,810 (-)EnsemblGRCr8
mRatBN7.21396,422,308 - 96,432,044 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,422,302 - 96,432,068 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1398,928,570 - 98,938,306 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013100,327,408 - 100,337,144 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01397,510,809 - 97,520,545 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013102,780,885 - 102,790,621 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13102,780,877 - 102,790,639 (-)Ensemblrn6Rnor6.0
Rnor_5.013107,456,593 - 107,466,329 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413100,875,932 - 100,885,668 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1395,939,418 - 95,949,154 (-)NCBICelera
RGSC_v3.113101,064,974 - 101,093,525 (-)NCBI
Cytogenetic Map13q26NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334  


Genomics

Comparative Map Data
C13h1orf115
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81398,953,841 - 98,963,577 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1398,953,843 - 98,963,810 (-)EnsemblGRCr8
mRatBN7.21396,422,308 - 96,432,044 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,422,302 - 96,432,068 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1398,928,570 - 98,938,306 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013100,327,408 - 100,337,144 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01397,510,809 - 97,520,545 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013102,780,885 - 102,790,621 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13102,780,877 - 102,790,639 (-)Ensemblrn6Rnor6.0
Rnor_5.013107,456,593 - 107,466,329 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.413100,875,932 - 100,885,668 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1395,939,418 - 95,949,154 (-)NCBICelera
RGSC_v3.113101,064,974 - 101,093,525 (-)NCBI
Cytogenetic Map13q26NCBI
C1orf115
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381220,690,363 - 220,699,153 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1220,690,363 - 220,699,153 (+)Ensemblhg38GRCh38
GRCh371220,863,705 - 220,872,495 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,930,251 - 218,939,122 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1194,082,992 - 194,091,863 (+)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1191,538,249 - 191,547,115 (+)NCBIHuRef
CHM1_11222,136,076 - 222,144,946 (+)NCBICHM1_1
T2T-CHM13v2.01219,930,068 - 219,938,857 (+)NCBIT2T-CHM13v2.0
C130074G19Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391184,604,123 - 184,615,233 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1184,604,123 - 184,615,415 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381184,871,926 - 184,883,036 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,871,926 - 184,883,218 (-)Ensemblmm10GRCm38
MGSCv371186,695,805 - 186,706,915 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361186,572,714 - 186,583,802 (-)NCBIMGSCv36mm8
Celera1191,834,798 - 191,845,748 (-)NCBICelera
Cytogenetic Map1H5NCBI
cM Map189.22NCBI
CUNH1orf115
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555203,064,235 - 3,065,978 (-)NCBIChiLan1.0ChiLan1.0
C1H1orf115
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2128,700,936 - 28,709,942 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1128,662,763 - 28,671,779 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01196,276,253 - 196,285,549 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11201,311,283 - 201,320,273 (+)NCBIPanPan1.1PanPan1.1panPan2
CUNH1orf115
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934456,326,874 - 56,338,324 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366501,575,083 - 1,586,548 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366501,575,098 - 1,586,515 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C10H1orf115
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1010,115,923 - 10,127,714 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11010,115,917 - 10,127,722 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21012,317,346 - 12,329,153 (-)NCBISscrofa10.2Sscrofa10.2susScr3
C25H1orf115
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1258,844,455 - 8,853,459 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660559,123,440 - 9,132,712 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH1orf115
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248354,112,431 - 4,121,013 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in C13h1orf115
23 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:506
Count of miRNA genes:268
Interacting mature miRNAs:331
Transcripts:ENSRNOT00000003177
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1366451204106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat

Markers in Region
D13Got242  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21396,430,065 - 96,430,275 (+)MAPPERmRatBN7.2
Rnor_6.013102,788,643 - 102,788,852NCBIRnor6.0
Rnor_5.013107,464,351 - 107,464,560UniSTSRnor5.0
RGSC_v3.413100,883,690 - 100,883,899UniSTSRGSC3.4
Celera1395,947,176 - 95,947,385UniSTS
Cytogenetic Map13q26UniSTS
RH132582  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21396,422,508 - 96,422,691 (+)MAPPERmRatBN7.2
Rnor_6.013102,781,086 - 102,781,268NCBIRnor6.0
Rnor_5.013107,456,794 - 107,456,976UniSTSRnor5.0
RGSC_v3.413100,876,133 - 100,876,315UniSTSRGSC3.4
Celera1395,939,619 - 95,939,801UniSTS
RH 3.4 Map13653.0UniSTS
Cytogenetic Map13q26UniSTS
RH139065  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21396,424,065 - 96,424,257 (+)MAPPERmRatBN7.2
Rnor_6.013102,782,643 - 102,782,834NCBIRnor6.0
Rnor_5.013107,458,351 - 107,458,542UniSTSRnor5.0
RGSC_v3.413100,877,690 - 100,877,881UniSTSRGSC3.4
Celera1395,941,176 - 95,941,367UniSTS
RH 3.4 Map13652.7UniSTS
Cytogenetic Map13q26UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 159 91 90 59 46 59 6 310 146 11 138 81 92 31 14 14

Sequence


Ensembl Acc Id: ENSRNOT00000003177   ⟹   ENSRNOP00000003177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1398,953,843 - 98,963,810 (-)Ensembl
mRatBN7.2 Ensembl1396,422,302 - 96,432,068 (-)Ensembl
Rnor_6.0 Ensembl13102,780,877 - 102,790,639 (-)Ensembl
RefSeq Acc Id: NM_001100857   ⟹   NP_001094327
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81398,953,841 - 98,963,577 (-)NCBI
mRatBN7.21396,422,308 - 96,432,044 (-)NCBI
Rnor_6.013102,780,885 - 102,790,621 (-)NCBI
Rnor_5.013107,456,593 - 107,466,329 (-)NCBI
RGSC_v3.413100,875,932 - 100,885,668 (-)RGD
Celera1395,939,418 - 95,949,154 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001094327 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00158 (Get FASTA)   NCBI Sequence Viewer  
  EDL94905 (Get FASTA)   NCBI Sequence Viewer  
  Q3ZCQ0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001094327   ⟸   NM_001100857
- UniProtKB: Q3ZCQ0 (UniProtKB/Swiss-Prot),   A6JGP9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003177   ⟸   ENSRNOT00000003177

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3ZCQ0-F1-model_v2 AlphaFold Q3ZCQ0 1-140 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699088
Promoter ID:EPDNEW_R9612
Type:multiple initiation site
Name:RGD1310587_1
Description:similar to hypothetical protein FLJ14146
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013102,790,625 - 102,790,685EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310587 AgrOrtholog
BioCyc Gene G2FUF-16996 BioCyc
Ensembl Genes ENSRNOG00000002322 Ensembl
IMAGE_CLONE IMAGE:7096718 IMAGE-MGC_LOAD
  IMAGE:7096719 IMAGE-MGC_LOAD
InterPro DUF4710 UniProtKB/Swiss-Prot
KEGG Report rno:360894 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114576 IMAGE-MGC_LOAD
  MGC:93701 IMAGE-MGC_LOAD
NCBI Gene 360894 ENTREZGENE
PANTHER PTHR14680 UniProtKB/Swiss-Prot
  SI:DKEY-126G1.9-RELATED UniProtKB/Swiss-Prot
Pfam DUF4710 UniProtKB/Swiss-Prot
PhenoGen C13h1orf115 PhenoGen
RatGTEx ENSRNOG00000002322 RatGTEx
UniProt A0A8L2Q047_RAT UniProtKB/TrEMBL
  A6JGP9 ENTREZGENE, UniProtKB/TrEMBL
  CA115_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C13h1orf115   similar to human chromosome 1 open reading frame 115  RGD1310587  similar to hypothetical protein FLJ14146  Symbol and Name Changed 1299863 APPROVED
2005-12-06 RGD1310587  similar to hypothetical protein FLJ14146  RGD1310587_predicted  similar to hypothetical protein FLJ14146 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1310587_predicted  similar to hypothetical protein FLJ14146 (predicted)  LOC360894_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC360894_predicted  similar to hypothetical protein FLJ14146 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL