Tpgs2 (tubulin polyglutamylase complex subunit 2)

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Gene: Tpgs2 (tubulin polyglutamylase complex subunit 2) Rattus norvegicus

Analyze

Symbol:

Tpgs2

Name:

tubulin polyglutamylase complex subunit 2

RGD ID:

1310571

Description:

Predicted to be located in centriolar satellite; cytoplasm; and microtubule. Orthologous to human TPGS2 (tubulin polyglutamylase complex subunit 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC361301; Pgs2; RGD1310571; similar to hypothetical protein

RGD Orthologs

Alliance Genes

More Info

more info ...

Related Pseudogenes:

Tpgs2-ps2

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	16,432,628 - 16,489,604 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	16,422,238 - 16,489,570 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	16,619,084 - 16,676,135 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	17,401,744 - 17,458,795 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	16,681,102 - 16,738,053 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	17,339,033 - 17,396,886 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	17,339,033 - 17,396,886 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	17,093,464 - 17,150,888 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	16,959,252 - 16,999,878 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	16,985,897 - 17,026,519 (-)	NCBI
Celera	18	16,343,298 - 16,400,482 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-hydroxypropanoic acid (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

bisphenol A (EXP,ISO)

carbamazepine (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

epoxiconazole (ISO)

folic acid (ISO)

hydrogen peroxide (ISO)

methimazole (EXP)

propiconazole (EXP)

rac-lactic acid (ISO)

sulfadimethoxine (EXP)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

centriolar satellite (IEA)

cytoplasm (IEA)

microtubule (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334

Genomics

Comparative Map Data

Tpgs2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	16,432,628 - 16,489,604 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	16,422,238 - 16,489,570 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	16,619,084 - 16,676,135 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	17,401,744 - 17,458,795 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	16,681,102 - 16,738,053 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	17,339,033 - 17,396,886 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	17,339,033 - 17,396,886 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	17,093,464 - 17,150,888 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	16,959,252 - 16,999,878 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	16,985,897 - 17,026,519 (-)	NCBI
Celera	18	16,343,298 - 16,400,482 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

TPGS2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	36,780,024 - 36,829,002 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	36,777,647 - 36,829,216 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	34,359,987 - 34,408,965 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	32,630,032 - 32,663,156 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	32,630,031 - 32,662,938	NCBI
Celera	18	31,185,470 - 31,218,594 (-)	NCBI		Celera
Cytogenetic Map	18	q12.2	NCBI
HuRef	18	31,218,876 - 31,268,065 (-)	NCBI		HuRef
CHM1_1	18	34,287,018 - 34,336,196 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	36,969,322 - 37,022,119 (-)	NCBI		T2T-CHM13v2.0

Tpgs2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	25,260,280 - 25,301,990 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	25,260,280 - 25,302,064 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	25,127,223 - 25,168,933 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	25,127,223 - 25,169,007 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	25,285,724 - 25,327,378 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	25,281,621 - 25,311,628 (-)	NCBI		MGSCv36	mm8
Celera	18	25,612,847 - 25,654,411 (-)	NCBI		Celera
Cytogenetic Map	18	A2	NCBI
cM Map	18	13.69	NCBI

Tpgs2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	23,286,833 - 23,319,207 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	23,286,950 - 23,319,207 (-)	NCBI	ChiLan1.0	ChiLan1.0

TPGS2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	18	39,875,377 - 39,917,523 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	30,039,892 - 30,082,047 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	33,597,438 - 33,639,528 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	33,590,771 - 33,639,528 (-)	Ensembl	panpan1.1		panPan2

TPGS2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	53,399,571 - 53,467,180 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	53,398,763 - 53,466,656 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	52,814,760 - 52,882,422 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	53,359,055 - 53,426,746 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	53,359,215 - 53,428,237 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	53,043,064 - 53,110,715 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	53,066,213 - 53,133,575 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	53,358,830 - 53,426,514 (+)	NCBI		UU_Cfam_GSD_1.0

Tpgs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	49,245,151 - 49,279,955 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936517	8,572,795 - 8,604,664 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936517	8,572,515 - 8,607,361 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TPGS2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	120,590,031 - 120,670,286 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	120,605,477 - 120,670,286 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	113,245,019 - 113,290,130 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TPGS2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	44,004,591 - 44,046,612 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	44,004,653 - 44,036,892 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	18,552,478 - 18,587,638 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tpgs2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624779	11,049,815 - 11,107,459 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624779	11,070,741 - 11,107,349 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tpgs2
160 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	371
Count of miRNA genes:	227
Interacting mature miRNAs:	254
Transcripts:	ENSRNOT00000020148
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552968	Pigfal19	Plasma insulin-like growth factor 1 level QTL 19	11.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	18	1	25758124	Rat
9590248	Scort10	Serum corticosterone level QTL 10	19.71	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	1	25758124	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	30558703	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34291613	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34291613	Rat
61388	Bp2	Blood pressure QTL 2	3.23		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	1	35374722	Rat
9589153	Insul31	Insulin level QTL 31	7.15	0.05	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	18	1	42547119	Rat
1641910	Colcr3	Colorectal carcinoma resistance QTL 3	5.02	0.000007	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor surface area measurement (CMO:0002078)	18	2249477	22066430	Rat
1641910	Colcr3	Colorectal carcinoma resistance QTL 3	5.02	0.000007	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	2249477	22066430	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4207941	60377792	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5185858	40503530	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11941791	31393320	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	11941791	31393320	Rat
12904690	Cm129	Cardiac mass QTL 129		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	11944273	26548295	Rat
12904689	Cm128	Cardiac mass QTL 128		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	11944273	26548295	Rat
12904693	Am20	Aortic mass QTL 20		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	11944273	26548295	Rat
12904695	Kidm73	Kidney mass QTL 73		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	11944273	26548295	Rat
12904691	Cm130	Cardiac mass QTL 130		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	11944273	26548295	Rat
12904680	Bw189	Body weight QTL 189		0.019	body mass (VT:0001259)	body weight (CMO:0000012)	18	11944273	26548295	Rat
2301410	Bp317	Blood pressure QTL 317		0.004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944273	26548295	Rat
1331781	Scl28	Serum cholesterol level QTL 28	3.995		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	11944299	24797117	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944299	31359530	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	11944299	41122201	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944299	52293055	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	11944299	59330563	Rat
6903359	Bp355	Blood pressure QTL 355	3.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944544	59796478	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	14951337	59951337	Rat

Markers in Region

RH128473

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	16,433,879 - 16,434,094 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	17,340,285 - 17,340,499	NCBI	Rnor6.0
Rnor_5.0	18	17,094,716 - 17,094,930	UniSTS	Rnor5.0
RGSC_v3.4	18	16,960,504 - 16,960,718	UniSTS	RGSC3.4
Celera	18	16,344,550 - 16,344,764	UniSTS
RH 3.4 Map	18	192.2	UniSTS
Cytogenetic Map	18	p12	UniSTS

RH137138

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	16,432,730 - 16,432,946 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	17,339,136 - 17,339,351	NCBI	Rnor6.0
Rnor_5.0	18	17,093,567 - 17,093,782	UniSTS	Rnor5.0
RGSC_v3.4	18	16,959,355 - 16,959,570	UniSTS	RGSC3.4
Celera	18	16,343,401 - 16,343,616	UniSTS
RH 3.4 Map	18	192.3	UniSTS
Cytogenetic Map	18	p12	UniSTS

RH139984

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	16,433,185 - 16,433,369 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	17,339,591 - 17,339,774	NCBI	Rnor6.0
Rnor_5.0	18	17,094,022 - 17,094,205	UniSTS	Rnor5.0
RGSC_v3.4	18	16,959,810 - 16,959,993	UniSTS	RGSC3.4
Celera	18	16,343,856 - 16,344,039	UniSTS
RH 3.4 Map	18	192.3	UniSTS
Cytogenetic Map	18	p12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	31	36	20	19	20		1	74	33	41	11
Low		12	21	21		21	8	10		2			8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014147	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079332	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000082963 ⟹ ENSRNOP00000070604

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	16,422,238 - 16,489,570 (-)	Ensembl
Rnor_6.0 Ensembl	18	17,340,495 - 17,396,805 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093690

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	16,432,653 - 16,489,570 (-)	Ensembl
Rnor_6.0 Ensembl	18	17,339,033 - 17,396,886 (-)	Ensembl

RefSeq Acc Id:

NM_001014147 ⟹ NP_001014169

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	18	16,432,628 - 16,489,570 (-)	NCBI
Rnor_6.0	18	17,339,033 - 17,396,886 (-)	NCBI
Rnor_5.0	18	17,093,464 - 17,150,888 (-)	NCBI
RGSC_v3.4	18	16,959,252 - 16,999,878 (-)	RGD
Celera	18	16,343,298 - 16,400,482 (-)	RGD

Sequence:

show sequence

CGTCAGCCGGCCGGCCGGCTGTGCACGGCAGCGCCGGGGACTGGGCCCGCCGCTGCCGCGCGCG
GGGTGAAGACGCGTGCCATGGAGGAGACACCGCCCCCAATGCAAGCCGGCAGCAAGCCGCACCT
TGAGAAGTTGACCCTGGGCGTAACTCGCATCCTGGAATCTTCCCCAGGTGTGACAGAGGTGAGC
ATAATAGAAAAGCTGCCTGCTGAGCGTCATATGATTTCTTCATGGGAACAGAAAAACAATTGTG
TGATGCCTGAGGATGTGAGAAACTTCTACTTGATGACCAATGGTTTTCACATGACCTGGAGTGT
GAAGCTAGATGACCACATTATTCCACTGGGAAGCATGGTGATTAATGGCATTTCCAAACTGACT
CAGCTCATCCAGTCCTCCGTGTACTCACTTCCTAATGCACCAACTCTGGCGGACCTGGAGGATG
ATTCTCAAGAAGGCAATGAAGACCACCAGCTCGAGAAGCCTCACTTTGACTGTCGCAGTGCGAT
ATTTGAGCTGGATTCATGCGGTGGGAATGGGAAAGTTTGCCTCGTCTACAAAAATGGGAAACCT
GGATTAGCTCATGACACTGAGATATGGTTCCTGGACAGAGCGTTATACTGGCATTTTCTCACAG
ACACCTTTACTGCCTATTACCGCCTGCTCATCACCCACCTGGGCCTGCCCCAGTGGCAATATGC
CTTTACCAGCTATGGCATTAGCCCACAGGCCAAGCAATGGTTCAGTATGTACAAACCCATCACC
TACAACACGAGCCTGCTCACAGAAGAGCCCGACACCTTTGTGAACAAGCTGGACCCCAGCAAAG
TGTTCAAGAGCAAGAACAAGATTTTAATCCCAAAAAAGAAAGGGCCTGTGCAGCCTGTCAGTGG
CCAGAAAGGGCCCGGGCCCTTAGCTCCGCCTACCTCTAAACCTTCTGCAGGCTGTGGAAACCCT
GTCCGAAAATAAGCGTTCTGTCACCTCCCATCAGTAATATCTGGGCACAGACAGCCCTGTGCAG
GCCCCACCATTCTCCTGAGAGACCAAAGCCTTAGGCCTTCACTCCCACTGTTGTTAGCCAGGAG
TTGGGACAATCACACTGAATTCTCCCCAGGAGTCCATTCCTCTGTAGGTTGTGCCAACCTCGTC
TCCAAATCCAACGACGGCTTTCAGATGTACCTAGAGCTTTCTTATGTCTGTACCCAATCCTTAA
CTTCTTAGCAGTAATTAGAGAGGTCACCCTCCCAAATAAACCCATGGTTTGAATCATCAGTAAC
GACTAGTCATGTGACCATCGCGGTTATGAAAATTTCATACCTTCAATTGCATTAGCCACACTTC
AGGGGTGCACCCAATAGTAGATTCCATATTGGCCAGCACAGAAAGGGGAACATTTCTGTCACAG
AAGCATTTTGGACAGAATTGCATGTGAACACTTTCATACTGTTCTTCAGATCCAATAATGTTTG
ACAACGTTACTGCCTTAACTTCATGGGCTTTATGCTTTAAGAAAACACTGTCAAAGTCTTGGGT
TCTTTACAACCAATACCACACATTTCACTTGAGTCATTTCTTTTTTAATTTGCTATAAAATATC
GTGTTCCTGATCAGTTTCTACATTTGCCAAAATCATCTTTAAAGAGATCGACCCTTGCTGTATT
TTATCTGTTAGTTCCCGGGGCATCGTTTGCAGACAAAGCCAGTCTGGTAAGAATTTCCAGCTCT
TCTGCTTATGCACAGTTGGATGCTGTTGCTCCCAGCTTGCTTAAGTCTAAGCAATGGTAGGTGT
GGGGTCCCAAGAAGCCTTTGTACATGAGTGTCCTATTCAAAAGGCGTTTCCCCCATAGCAGCAT
GATGGTATTAGACACTGCGCCGTCCCACAGGTTTATCATGTGGCATAGATTAGGCGTATAACAG
AAGTTCTGTAGAGAAAGACGTACTCTGATTTTCAGTTAAGAGTATCTGTTCCTTCGTCTGCACT
CCTGGCAATGGGCAGGAGTTTTGATGGCTGTATAATTTTTGTAATGATACTCCAGAGGTAGAAT
AAAGAGTTCTGAGGAGGAACAGACTGCACACTCCCTTTCCAGTTGGCCAACCTACTCAAACTTT
TCTACTATGGTGGTTGTCTGGGCTTCTTTCCTAGTATGTGATGGGAGCGAGAAGCCCCTGTCAT
TTTCTACCTGTACTTCTTCAACACCACTTTGAATGTTTAGTGAAGGTTTCAAATTCTTGTTTTG
GGGACTGGAAGGATGGCTCAGCAGTTAGGAGCGTGGACTACTCATGCAGAGGACCCGAGGTCAT
GTTGCAGCACCCATGTGAAGCAGTTTATGGCCCCTGGAACTCCAACTCCAGGAGGCTCAACATG
TTCTCCAAATTCCACAGGCACCTATGCACACACAAAGAAGGAAATAAAAACATTTGAAAAACTG
TTAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039096955 ⟹ XP_038952883

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	18	16,432,632 - 16,489,604 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014169	(Get FASTA)	NCBI Sequence Viewer
	XP_038952883	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79332	(Get FASTA)	NCBI Sequence Viewer
	EDL76145	(Get FASTA)	NCBI Sequence Viewer
	EDL76146	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000070604.2
	ENSRNOP00000084578
GenBank Protein	Q6AXS8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001014169 ⟸ NM_001014147

- UniProtKB:

Q6AXS8 (UniProtKB/Swiss-Prot), A6J2L4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEETPPPMQAGSKPHLEKLTLGVTRILESSPGVTEVSIIEKLPAERHMISSWEQKNNCVMPEDV
RNFYLMTNGFHMTWSVKLDDHIIPLGSMVINGISKLTQLIQSSVYSLPNAPTLADLEDDSQEGN
EDHQLEKPHFDCRSAIFELDSCGGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFTAY
YRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTSLLTEEPDTFVNKLDPSKVFKSKN
KILIPKKKGPVQPVSGQKGPGPLAPPTSKPSAGCGNPVRK

hide sequence

RefSeq Acc Id:

ENSRNOP00000070604 ⟸ ENSRNOT00000082963

RefSeq Acc Id:	XP_038952883 ⟸ XM_039096955
- Peptide Label:	isoform X1

Protein Domains

Knr4/Smi1-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AXS8-F1-model_v2	AlphaFold	Q6AXS8	1-296	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700669

Promoter ID:

EPDNEW_R11193

Type:

multiple initiation site

Name:

Tpgs2_1

Description:

tubulin polyglutamylase complex subunit 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	17,396,882 - 17,396,942	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310571	AgrOrtholog
BioCyc Gene	G2FUF-8139	BioCyc
Ensembl Genes	ENSRNOG00000054118	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000082963.2	UniProtKB/TrEMBL
	ENSRNOT00000093690	ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7096678	IMAGE-MGC_LOAD
InterPro	Knr4/Smi1-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Knr4/Smi1-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TPGS2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:361301	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94761	IMAGE-MGC_LOAD
NCBI Gene	361301	ENTREZGENE
PANTHER	PTHR31854	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Tpgs2	PhenoGen
RatGTEx	ENSRNOG00000054118	RatGTEx
SMART	SMI1_KNR4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF160631	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A6J2L4	ENTREZGENE, UniProtKB/TrEMBL
	F1LR55_RAT	UniProtKB/TrEMBL
	Q6AXS8	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-12-06	Tpgs2	tubulin polyglutamylase complex subunit 2	RGD1310571	similar to hypothetical protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1310571	similar to hypothetical protein	RGD1310571_predicted	similar to hypothetical protein (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1310571_predicted	similar to hypothetical protein (predicted)	LOC361301_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC361301_predicted	similar to hypothetical protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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