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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ipo9 | Rat | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of IPO9 mRNA | CTD | PMID:27840820 | Ipo9 | Rat | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | IPO9 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to IPO9 protein | CTD | PMID:32991956 | Ipo9 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of IPO9 mRNA | CTD | PMID:33387578 | Ipo9 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of IPO9 mRNA | CTD | PMID:21346803 | Ipo9 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of IPO9 mRNA | CTD | PMID:30851411 | Ipo9 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of IPO9 protein | CTD | PMID:34915118 | Ipo9 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | IPO9 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of IPO9 protein | CTD | PMID:34186270 | Ipo9 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of IPO9 mRNA | CTD | PMID:28959563 | Ipo9 | Rat | aflatoxin B1 | increases methylation | ISO | IPO9 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of IPO9 gene | CTD | PMID:27153756 | Ipo9 | Rat | all-trans-retinoic acid | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of IPO9 mRNA | CTD | PMID:33167477 | Ipo9 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of IPO9 mRNA | CTD | PMID:30779732 | Ipo9 | Rat | antirheumatic drug | increases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of IPO9 mRNA | CTD | PMID:24449571 | Ipo9 | Rat | atrazine | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of IPO9 mRNA | CTD | PMID:22378314 | Ipo9 | Rat | benzo[a]pyrene | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of IPO9 mRNA | CTD | PMID:26238291 | Ipo9 | Rat | benzo[a]pyrene | increases methylation | ISO | IPO9 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of IPO9 promoter | CTD | PMID:27901495 | Ipo9 | Rat | benzo[a]pyrene | affects methylation | ISO | IPO9 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of IPO9 3' UTR | CTD | PMID:27901495 | Ipo9 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Ipo9 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of IPO9 mRNA | CTD | PMID:34319233 | Ipo9 | Rat | bisphenol A | decreases expression | ISO | Ipo9 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of IPO9 mRNA | CTD | PMID:26063408 | Ipo9 | Rat | bisphenol A | increases expression | ISO | IPO9 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of IPO9 protein | CTD | PMID:34186270 | Ipo9 | Rat | bisphenol A | multiple interactions | ISO | IPO9 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of IPO9 gene | CTD | PMID:31601247 | Ipo9 | Rat | bisphenol A | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of IPO9 protein | CTD | PMID:37567409 | Ipo9 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of IPO9 mRNA | CTD | PMID:32145629 | Ipo9 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of IPO9 mRNA | CTD | PMID:30816183 more ... | Ipo9 | Rat | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of IPO9 mRNA | CTD | PMID:24136188 | Ipo9 | Rat | butanal | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of IPO9 mRNA | CTD | PMID:26079696 | Ipo9 | Rat | cadmium dichloride | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of IPO9 mRNA | CTD | PMID:38568856 | Ipo9 | Rat | calcitriol | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of IPO9 mRNA | CTD | PMID:16847355 | Ipo9 | Rat | carbamazepine | affects expression | ISO | IPO9 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of IPO9 mRNA | CTD | PMID:25979313 | Ipo9 | Rat | carbon nanotube | increases expression | ISO | Ipo9 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of IPO9 mRNA | CTD | PMID:25554681 | Ipo9 | Rat | CGP 52608 | multiple interactions | ISO | IPO9 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to IPO9 gene] | CTD | PMID:28238834 | Ipo9 | Rat | choline | multiple interactions | ISO | Ipo9 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of IPO9 gene | CTD | PMID:20938992 | Ipo9 | Rat | cobalt dichloride | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of IPO9 mRNA | CTD | PMID:19320972 and PMID:19376846 | Ipo9 | Rat | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of IPO9 mRNA | CTD | PMID:30556269 | Ipo9 | Rat | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of IPO9 mRNA | CTD | PMID:30556269 | Ipo9 | Rat | copper(II) sulfate | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of IPO9 mRNA | CTD | PMID:19549813 | Ipo9 | Rat | coumestrol | multiple interactions | ISO | IPO9 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of IPO9 mRNA | CTD | PMID:19167446 | Ipo9 | Rat | coumestrol | increases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of IPO9 mRNA | CTD | PMID:19167446 | Ipo9 | Rat | dicrotophos | increases expression | ISO | IPO9 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of IPO9 mRNA | CTD | PMID:28302478 | Ipo9 | Rat | dorsomorphin | multiple interactions | ISO | IPO9 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of IPO9 mRNA | CTD | PMID:27188386 | Ipo9 | Rat | doxorubicin | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of IPO9 mRNA | CTD | PMID:29803840 | Ipo9 | Rat | ethanol | multiple interactions | ISO | Ipo9 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of IPO9 mRNA | CTD | PMID:30319688 | Ipo9 | Rat | fenthion | decreases expression | ISO | Ipo9 (Mus musculus) | 6480464 | Fenthion results in decreased expression of IPO9 mRNA | CTD | PMID:34813904 | Ipo9 | Rat | folic acid | multiple interactions | ISO | Ipo9 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of IPO9 gene | CTD | PMID:20938992 | Ipo9 | Rat | fulvestrant | multiple interactions | ISO | IPO9 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of IPO9 gene | CTD | PMID:31601247 | Ipo9 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of IPO9 mRNA | CTD | PMID:22061828 and PMID:33387578 | Ipo9 | Rat | ivermectin | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of IPO9 protein | CTD | PMID:32959892 | Ipo9 | Rat | L-methionine | multiple interactions | ISO | Ipo9 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of IPO9 gene | CTD | PMID:20938992 | Ipo9 | Rat | methidathion | decreases expression | ISO | Ipo9 (Mus musculus) | 6480464 | methidathion results in decreased expression of IPO9 mRNA | CTD | PMID:34813904 | Ipo9 | Rat | methylmercury chloride | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of IPO9 mRNA | CTD | PMID:28001369 | Ipo9 | Rat | ozone | multiple interactions | ISO | IPO9 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of IPO9 mRNA | CTD | PMID:35430440 | Ipo9 | Rat | paracetamol | increases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of IPO9 mRNA | CTD | PMID:22230336 | Ipo9 | Rat | rac-lactic acid | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of IPO9 mRNA | CTD | PMID:30851411 | Ipo9 | Rat | resveratrol | multiple interactions | ISO | IPO9 (Homo sapiens) | 6480464 | [Coumestrol co-treated with Resveratrol] results in increased expression of IPO9 mRNA and [Plant Extracts co-treated with Resveratrol] results in increased expression of IPO9 mRNA | CTD | PMID:19167446 and PMID:23557933 | Ipo9 | Rat | rotenone | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of IPO9 mRNA | CTD | PMID:29955902 | Ipo9 | Rat | SB 431542 | multiple interactions | ISO | IPO9 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | Ipo9 | Rat | sodium arsenite | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of IPO9 mRNA | CTD | PMID:38568856 | Ipo9 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of IPO9 mRNA | CTD | PMID:15336504 | Ipo9 | Rat | tetrachloromethane | increases expression | ISO | Ipo9 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of IPO9 mRNA | CTD | PMID:31919559 | Ipo9 | Rat | tetrahydropalmatine | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | tetrahydropalmatine results in decreased expression of IPO9 protein | CTD | PMID:20109541 | Ipo9 | Rat | thiram | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Thiram results in decreased expression of IPO9 mRNA | CTD | PMID:38568856 | Ipo9 | Rat | titanium dioxide | decreases methylation | ISO | Ipo9 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of IPO9 gene | CTD | PMID:35295148 | Ipo9 | Rat | trichostatin A | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of IPO9 mRNA | CTD | PMID:26272509 | Ipo9 | Rat | trichostatin A | multiple interactions | ISO | IPO9 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of IPO9 mRNA | CTD | PMID:27188386 | Ipo9 | Rat | triphenyl phosphate | affects expression | ISO | IPO9 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of IPO9 mRNA | CTD | PMID:37042841 | Ipo9 | Rat | triptonide | affects expression | ISO | Ipo9 (Mus musculus) | 6480464 | triptonide affects the expression of IPO9 mRNA | CTD | PMID:33045310 | Ipo9 | Rat | tungsten | decreases expression | ISO | Ipo9 (Mus musculus) | 6480464 | Tungsten results in decreased expression of IPO9 mRNA | CTD | PMID:30912803 | Ipo9 | Rat | urethane | decreases expression | ISO | IPO9 (Homo sapiens) | 6480464 | Urethane results in decreased expression of IPO9 mRNA | CTD | PMID:28818685 | Ipo9 | Rat | valproic acid | affects expression | ISO | IPO9 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of IPO9 mRNA | CTD | PMID:25979313 | |