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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Usp49 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of USP49 mRNA] | CTD | PMID:31150632 | Usp49 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Usp49 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of USP49 mRNA | CTD | PMID:22206623 | Usp49 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Usp49 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Usp49 | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Usp49 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Usp49 | Rat | 2-hydroxypropanoic acid | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of USP49 mRNA | CTD | PMID:30851411 | Usp49 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Usp49 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of USP49 mRNA | CTD | PMID:39298647 | Usp49 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Usp49 (Mus musculus) | 6480464 | bisphenol S affects the methylation of USP49 gene | CTD | PMID:31683443 | Usp49 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Usp49 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of USP49 exon | CTD | PMID:33297965 | Usp49 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of USP49 mRNA | CTD | PMID:24780913 and PMID:25825206 | Usp49 | Rat | all-trans-retinoic acid | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of USP49 mRNA | CTD | PMID:21934132 | Usp49 | Rat | aristolochic acid A | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of USP49 mRNA | CTD | PMID:33212167 | Usp49 | Rat | beta-lapachone | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of USP49 mRNA | CTD | PMID:38218311 | Usp49 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of USP49 mRNA | CTD | PMID:25181051 | Usp49 | Rat | bisphenol A | decreases expression | ISO | Usp49 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of USP49 mRNA | CTD | PMID:33221593 | Usp49 | Rat | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of USP49 mRNA | CTD | PMID:32479839 | Usp49 | Rat | cadmium atom | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of USP49 mRNA | CTD | PMID:35301059 | Usp49 | Rat | cadmium dichloride | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of USP49 mRNA | CTD | PMID:38568856 | Usp49 | Rat | cadmium dichloride | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of USP49 mRNA | CTD | PMID:35301059 | Usp49 | Rat | chlorpyrifos | decreases expression | ISO | Usp49 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of USP49 mRNA | CTD | PMID:37019170 | Usp49 | Rat | copper atom | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of USP49 mRNA | CTD | PMID:20971185 | Usp49 | Rat | copper(0) | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of USP49 mRNA | CTD | PMID:20971185 | Usp49 | Rat | Dibutyl phosphate | affects expression | ISO | USP49 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of USP49 mRNA | CTD | PMID:37042841 | Usp49 | Rat | dorsomorphin | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Usp49 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of USP49 mRNA | CTD | PMID:29391264 | Usp49 | Rat | entinostat | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | entinostat results in decreased expression of USP49 mRNA | CTD | PMID:26272509 | Usp49 | Rat | ethyl methanesulfonate | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of USP49 mRNA | CTD | PMID:23649840 | Usp49 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of USP49 mRNA | CTD | PMID:30307764 | Usp49 | Rat | formaldehyde | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of USP49 mRNA | CTD | PMID:23649840 | Usp49 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of USP49 mRNA | CTD | PMID:33387578 | Usp49 | Rat | hydralazine | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of USP49 mRNA | CTD | PMID:17183730 | Usp49 | Rat | hydrogen peroxide | affects expression | ISO | USP49 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of USP49 mRNA | CTD | PMID:21179406 | Usp49 | Rat | methyl methanesulfonate | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of USP49 mRNA | CTD | PMID:23649840 | Usp49 | Rat | methylmercury chloride | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of USP49 mRNA | CTD | PMID:28001369 | Usp49 | Rat | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of USP49 mRNA | CTD | PMID:28801915 | Usp49 | Rat | ozone | multiple interactions | ISO | Usp49 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of USP49 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of USP49 mRNA | CTD | PMID:34911549 | Usp49 | Rat | panobinostat | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of USP49 mRNA | CTD | PMID:27188386 | Usp49 | Rat | panobinostat | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of USP49 mRNA | CTD | PMID:26272509 | Usp49 | Rat | paracetamol | affects expression | ISO | Usp49 (Mus musculus) | 6480464 | Acetaminophen affects the expression of USP49 mRNA | CTD | PMID:17562736 | Usp49 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of USP49 mRNA | CTD | PMID:33387578 | Usp49 | Rat | PCB138 | multiple interactions | ISO | Usp49 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Usp49 | Rat | pentanal | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | pentanal results in decreased expression of USP49 mRNA | CTD | PMID:26079696 | Usp49 | Rat | phenylmercury acetate | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of USP49 mRNA | CTD | PMID:26272509 | Usp49 | Rat | phenylmercury acetate | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of USP49 mRNA | CTD | PMID:27188386 | Usp49 | Rat | pirinixic acid | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of USP49 mRNA | CTD | PMID:19710929 | Usp49 | Rat | rac-lactic acid | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of USP49 mRNA | CTD | PMID:30851411 | Usp49 | Rat | SB 431542 | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Usp49 | Rat | silicon dioxide | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of USP49 mRNA | CTD | PMID:23806026 | Usp49 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of USP49 mRNA | CTD | PMID:19281266 | Usp49 | Rat | sunitinib | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of USP49 mRNA | CTD | PMID:31533062 | Usp49 | Rat | temozolomide | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of USP49 mRNA | CTD | PMID:31758290 | Usp49 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of USP49 mRNA | CTD | PMID:31150632 | Usp49 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of USP49 mRNA] | CTD | PMID:31150632 | Usp49 | Rat | thimerosal | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of USP49 mRNA | CTD | PMID:27188386 | Usp49 | Rat | thiram | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | Thiram results in increased expression of USP49 mRNA | CTD | PMID:38568856 | Usp49 | Rat | titanium dioxide | increases methylation | ISO | Usp49 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of USP49 gene | CTD | PMID:35295148 | Usp49 | Rat | titanium dioxide | decreases methylation | ISO | Usp49 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of USP49 promoter | CTD | PMID:35295148 | Usp49 | Rat | torcetrapib | increases expression | ISO | USP49 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of USP49 mRNA | CTD | PMID:23228038 | Usp49 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of USP49 mRNA | CTD | PMID:33387578 | Usp49 | Rat | trichostatin A | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of USP49 mRNA | CTD | PMID:24935251 and PMID:26272509 | Usp49 | Rat | trichostatin A | affects expression | ISO | USP49 (Homo sapiens) | 6480464 | trichostatin A affects the expression of USP49 mRNA | CTD | PMID:28542535 | Usp49 | Rat | trichostatin A | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of USP49 mRNA | CTD | PMID:27188386 | Usp49 | Rat | triptonide | increases expression | ISO | Usp49 (Mus musculus) | 6480464 | triptonide results in increased expression of USP49 mRNA | CTD | PMID:33045310 | Usp49 | Rat | valproic acid | multiple interactions | ISO | USP49 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of USP49 mRNA more ... | CTD | PMID:17183730 and PMID:27188386 | Usp49 | Rat | valproic acid | affects expression | ISO | Usp49 (Mus musculus) | 6480464 | Valproic Acid affects the expression of USP49 mRNA | CTD | PMID:17292431 | Usp49 | Rat | valproic acid | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of USP49 mRNA | CTD | PMID:23179753 more ... | Usp49 | Rat | vorinostat | decreases expression | ISO | USP49 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of USP49 mRNA | CTD | PMID:26272509 and PMID:27188386 | |