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Gene: Parp14 (poly (ADP-ribose) polymerase family, member 14) Rattus norvegicus

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Symbol:

Parp14

Name:

poly (ADP-ribose) polymerase family, member 14

RGD ID:

1310490

Description:

Predicted to enable several functions, including NAD+ binding activity; pentosyltransferase activity; and transcription corepressor activity. Predicted to be involved in several processes, including protein poly-ADP-ribosylation; regulation of cytokine-mediated signaling pathway; and regulation of tyrosine phosphorylation of STAT protein. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm and nucleus. Orthologous to human PARP14 (poly(ADP-ribose) polymerase family member 14); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; interleukin-4 signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC303903; poly [ADP-ribose] polymerase 14; RGD1310490; similar to hypothetical protein MGC29390

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	78,408,134 - 78,440,201 (+)	NCBI		GRCr8
mRatBN7.2	11	64,902,848 - 64,934,916 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	64,902,785 - 64,934,916 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	73,724,829 - 73,756,951 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	66,387,099 - 66,419,216 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	65,418,357 - 65,450,473 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	68,105,442 - 68,137,509 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	68,105,369 - 68,137,535 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	71,194,913 - 71,226,980 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	66,736,902 - 66,768,977 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	66,800,714 - 66,824,843 (+)	NCBI
Celera	11	64,365,191 - 64,397,200 (+)	NCBI		Celera
Cytogenetic Map	11	q22	NCBI

JBrowse:

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Model

Annotation Click to see Annotation Detail View

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Parp14	Rat	alkaptonuria		ISO	RGD:1344897	8554872	ClinVar Annotator: match by term: Alkaptonuria	ClinVar	PMID:12501223\|PMID:19862842\|PMID:28492532
Parp14	Rat	familial hypocalciuric hypercalcemia		ISO	RGD:1344897	8554872	ClinVar Annotator: match by term: Familial hypocalciuric hypercalcemia	ClinVar	PMID:28492532
Parp14	Rat	Primary Lymphedema with Myelodysplasia		ISO	RGD:1344897	8554872	ClinVar Annotator: match by term: Lymphedema, primary, with myelodysplasia	ClinVar	PMID:19449416\|PMID:22147895\|PMID:25741868

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Parp14	Rat	(-)-alpha-phellandrene	increases expression	ISO	RGD:1344897	6480464	alpha phellandrene results in increased expression of PARP14 mRNA	CTD	PMID:25075043
Parp14	Rat	(1->4)-beta-D-glucan	multiple interactions	ISO	RGD:1613887	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PARP14 mRNA	CTD	PMID:36331819
Parp14	Rat	1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene	multiple interactions	ISO	RGD:1613887	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Parp14	Rat	1,2-dimethylhydrazine	increases expression	EXP		6480464	1,2-Dimethylhydrazine results in increased expression of PARP14 mRNA	CTD	PMID:27840820
Parp14	Rat	1,2-dimethylhydrazine	affects expression	ISO	RGD:1613887	6480464	1,2-Dimethylhydrazine affects the expression of PARP14 mRNA	CTD	PMID:22206623
Parp14	Rat	17beta-estradiol	increases expression	ISO	RGD:1344897	6480464	Estradiol results in increased expression of PARP14 mRNA	CTD	PMID:21185374
Parp14	Rat	17beta-estradiol	affects expression	ISO	RGD:1613887	6480464	Estradiol affects the expression of PARP14 mRNA	CTD	PMID:39298647
Parp14	Rat	17beta-estradiol	multiple interactions	EXP		6480464	[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PARP14 mRNA	CTD	PMID:32741896
Parp14	Rat	17beta-estradiol	multiple interactions	ISO	RGD:1344897	6480464	[Estradiol co-treated with TGFB1 protein] results in decreased expression of PARP14 mRNA	CTD	PMID:30165855
Parp14	Rat	17beta-estradiol 3-benzoate	multiple interactions	EXP		6480464	[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PARP14 mRNA	CTD	PMID:32741896
Parp14	Rat	2,2',4,4',5,5'-hexachlorobiphenyl	multiple interactions	ISO	RGD:1613887	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Parp14	Rat	2,2',4,4'-Tetrabromodiphenyl ether	increases expression	ISO	RGD:1344897	6480464	2,2',4,4'-tetrabromodiphenyl ether results in increased expression of PARP14 mRNA	CTD	PMID:23146750
Parp14	Rat	2,2',4,4'-Tetrabromodiphenyl ether	decreases expression	ISO	RGD:1344897	6480464	2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of PARP14 protein	CTD	PMID:31675489
Parp14	Rat	2,2',4,4'-Tetrabromodiphenyl ether	affects expression	ISO	RGD:1613887	6480464	2,2',4,4'-tetrabromodiphenyl ether affects the expression of PARP14 mRNA	CTD	PMID:30294300
Parp14	Rat	2,2',5,5'-tetrachlorobiphenyl	decreases expression	EXP		6480464	2,5,2',5'-tetrachlorobiphenyl results in decreased expression of PARP14 mRNA	CTD	PMID:23829299
Parp14	Rat	2,2',5,5'-tetrachlorobiphenyl	multiple interactions	ISO	RGD:1613887	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Parp14	Rat	2,3',4,4',5-Pentachlorobiphenyl	increases expression	ISO	RGD:1613887	6480464	2,3',4,4',5-pentachlorobiphenyl results in increased expression of PARP14 mRNA	CTD	PMID:31388691
Parp14	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1613887	6480464	Tetrachlorodibenzodioxin affects the expression of PARP14 mRNA	CTD	PMID:21570461
Parp14	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of PARP14 mRNA	CTD	PMID:33387578
Parp14	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of PARP14 mRNA	CTD	PMID:34747641
Parp14	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:1344897	6480464	Tetrachlorodibenzodioxin results in increased expression of PARP14 mRNA	CTD	PMID:20106945\|PMID:21632981
Parp14	Rat	2,4,4'-trichlorobiphenyl	multiple interactions	ISO	RGD:1613887	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Parp14	Rat	2,4,6-tribromophenol	decreases expression	ISO	RGD:1344897	6480464	2,4,6-tribromophenol results in decreased expression of PARP14 mRNA	CTD	PMID:31675489
Parp14	Rat	3,3',5,5'-tetrabromobisphenol A	decreases expression	ISO	RGD:1344897	6480464	tetrabromobisphenol A results in decreased expression of PARP14 protein	CTD	PMID:31675489
Parp14	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	RGD:1613887	6480464	bisphenol S results in increased expression of PARP14 mRNA	CTD	PMID:30951980
Parp14	Rat	4,4'-sulfonyldiphenol	affects expression	ISO	RGD:1613887	6480464	bisphenol S affects the expression of PARP14 mRNA	CTD	PMID:39298647
Parp14	Rat	4-(ethoxymethylene)-2-phenyloxazol-5-one	increases expression	EXP		6480464	Oxazolone results in increased expression of PARP14 mRNA	CTD	PMID:21893156
Parp14	Rat	5-fluorouracil	increases expression	ISO	RGD:1344897	6480464	Fluorouracil results in increased expression of PARP14 mRNA	CTD	PMID:17039268
Parp14	Rat	acetamide	affects expression	EXP		6480464	acetamide affects the expression of PARP14 mRNA	CTD	PMID:31881176
Parp14	Rat	aconitine	decreases expression	EXP		6480464	Aconitine results in decreased expression of PARP14 protein	CTD	PMID:33236894
Parp14	Rat	aflatoxin B1	increases expression	ISO	RGD:1613887	6480464	Aflatoxin B1 results in increased expression of PARP14 mRNA	CTD	PMID:19770486
Parp14	Rat	aflatoxin B1	decreases methylation	ISO	RGD:1344897	6480464	Aflatoxin B1 results in decreased methylation of PARP14 gene	CTD	PMID:27153756
Parp14	Rat	aldehydo-D-glucose	multiple interactions	ISO	RGD:1613887	6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Parp14	Rat	all-trans-retinoic acid	increases expression	ISO	RGD:1344897	6480464	Tretinoin results in increased expression of PARP14 mRNA	CTD	PMID:23830798\|PMID:33167477
Parp14	Rat	all-trans-retinoic acid	multiple interactions	ISO	RGD:1613887	6480464	[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PARP14 mRNA	CTD	PMID:36189433
Parp14	Rat	alpha-phellandrene	increases expression	ISO	RGD:1344897	6480464	alpha phellandrene results in increased expression of PARP14 mRNA	CTD	PMID:25075043
Parp14	Rat	benzo[a]pyrene	decreases expression	ISO	RGD:1613887	6480464	Benzo(a)pyrene results in decreased expression of PARP14 mRNA	CTD	PMID:19770486
Parp14	Rat	benzo[a]pyrene	affects methylation	ISO	RGD:1344897	6480464	Benzo(a)pyrene affects the methylation of PARP14 intron	CTD	PMID:30157460
Parp14	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1344897	6480464	Benzo(a)pyrene results in increased expression of PARP14 mRNA	CTD	PMID:20106945\|PMID:21632981\|PMID:26238291
Parp14	Rat	benzo[a]pyrene diol epoxide I	increases expression	ISO	RGD:1344897	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PARP14 mRNA	CTD	PMID:26238291
Parp14	Rat	benzo[e]pyrene	increases methylation	ISO	RGD:1344897	6480464	benzo(e)pyrene results in increased methylation of PARP14 intron	CTD	PMID:30157460
Parp14	Rat	bisphenol A	increases expression	ISO	RGD:1613887	6480464	bisphenol A results in increased expression of PARP14 mRNA	CTD	PMID:26063408
Parp14	Rat	bisphenol A	decreases expression	ISO	RGD:1344897	6480464	bisphenol A results in decreased expression of PARP14 protein	CTD	PMID:31675489
Parp14	Rat	bisphenol A	multiple interactions	ISO	RGD:1344897	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of PARP14 gene	CTD	PMID:31601247
Parp14	Rat	bisphenol A	decreases methylation	ISO	RGD:1344897	6480464	bisphenol A results in decreased methylation of PARP14 gene	CTD	PMID:31601247
Parp14	Rat	bisphenol A	increases expression	ISO	RGD:1344897	6480464	bisphenol A results in increased expression of PARP14 mRNA	CTD	PMID:29275510
Parp14	Rat	bisphenol A	increases methylation	EXP		6480464	bisphenol A results in increased methylation of PARP14 gene	CTD	PMID:28505145
Parp14	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of PARP14 mRNA	CTD	PMID:30816183\|PMID:32528016\|PMID:34947998
Parp14	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of PARP14 mRNA	CTD	PMID:25181051
Parp14	Rat	bromobenzene	decreases expression	EXP		6480464	bromobenzene results in decreased expression of PARP14 mRNA	CTD	PMID:32479839
Parp14	Rat	buspirone	decreases expression	EXP		6480464	Buspirone results in decreased expression of PARP14 mRNA	CTD	PMID:24136188
Parp14	Rat	cadmium dichloride	decreases expression	EXP		6480464	Cadmium Chloride results in decreased expression of PARP14 mRNA	CTD	PMID:33453195
Parp14	Rat	carbon nanotube	increases expression	ISO	RGD:1613887	6480464	Nanotubes, Carbon analog results in increased expression of PARP14 mRNA; Nanotubes, Carbon results in increased more ...	CTD	PMID:25554681
Parp14	Rat	chlorohydrocarbon	multiple interactions	EXP		6480464	[Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of more ...	CTD	PMID:30744511
Parp14	Rat	chromium(6+)	affects expression	ISO	RGD:1613887	6480464	chromium hexavalent ion affects the expression of PARP14 mRNA	CTD	PMID:28472532
Parp14	Rat	ciguatoxin CTX1B	affects expression	ISO	RGD:1613887	6480464	Ciguatoxins affects the expression of PARP14 mRNA	CTD	PMID:18353800
Parp14	Rat	cisplatin	increases expression	ISO	RGD:1344897	6480464	Cisplatin results in increased expression of PARP14 mRNA	CTD	PMID:27594783
Parp14	Rat	clofibrate	decreases expression	ISO	RGD:1613887	6480464	Clofibrate results in decreased expression of PARP14 mRNA	CTD	PMID:23811191
Parp14	Rat	cobalt dichloride	decreases expression	EXP		6480464	cobaltous chloride results in decreased expression of PARP14 mRNA	CTD	PMID:24386269
Parp14	Rat	Cuprizon	increases expression	EXP		6480464	Cuprizone results in increased expression of PARP14 mRNA	CTD	PMID:26577399\|PMID:27523638
Parp14	Rat	D-glucose	multiple interactions	ISO	RGD:1613887	6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Parp14	Rat	decabromodiphenyl ether	increases expression	ISO	RGD:1344897	6480464	decabromobiphenyl ether results in increased expression of PARP14 protein	CTD	PMID:31675489
Parp14	Rat	dioxygen	multiple interactions	ISO	RGD:1613887	6480464	[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PARP14 mRNA	CTD	PMID:30529165
Parp14	Rat	dioxygen	multiple interactions	EXP		6480464	[dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with more ...	CTD	PMID:33729688
Parp14	Rat	diquat	decreases expression	ISO	RGD:1613887	6480464	Diquat results in decreased expression of PARP14 mRNA	CTD	PMID:36851058
Parp14	Rat	endosulfan	decreases expression	EXP		6480464	Endosulfan results in decreased expression of PARP14 mRNA	CTD	PMID:29391264
Parp14	Rat	ethanol	affects expression	ISO	RGD:1613887	6480464	Ethanol affects the expression of PARP14 mRNA	CTD	PMID:26730594
Parp14	Rat	ethyl methanesulfonate	increases expression	ISO	RGD:1344897	6480464	Ethyl Methanesulfonate results in increased expression of PARP14 mRNA	CTD	PMID:23649840
Parp14	Rat	fenthion	decreases expression	ISO	RGD:1613887	6480464	Fenthion results in decreased expression of PARP14 mRNA	CTD	PMID:34813904
Parp14	Rat	finasteride	decreases expression	EXP		6480464	Finasteride results in decreased expression of PARP14 mRNA	CTD	PMID:24136188
Parp14	Rat	flutamide	decreases expression	EXP		6480464	Flutamide results in decreased expression of PARP14 mRNA	CTD	PMID:24793618
Parp14	Rat	fructose	multiple interactions	ISO	RGD:1613887	6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Parp14	Rat	fulvestrant	multiple interactions	ISO	RGD:1344897	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of PARP14 gene	CTD	PMID:31601247
Parp14	Rat	furan	decreases expression	EXP		6480464	furan results in decreased expression of PARP14 mRNA	CTD	PMID:25539665\|PMID:26194646
Parp14	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of PARP14 mRNA	CTD	PMID:22061828
Parp14	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of PARP14 mRNA	CTD	PMID:33387578
Parp14	Rat	glucose	multiple interactions	ISO	RGD:1613887	6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Parp14	Rat	glycidol	decreases expression	EXP		6480464	glycidol results in decreased expression of PARP14 mRNA	CTD	PMID:24395379
Parp14	Rat	glyphosate	multiple interactions	ISO	RGD:1613887	6480464	[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ...	CTD	PMID:37567420
Parp14	Rat	hydralazine	multiple interactions	ISO	RGD:1344897	6480464	[Hydralazine co-treated with Valproic Acid] results in increased expression of PARP14 mRNA	CTD	PMID:17183730
Parp14	Rat	inulin	multiple interactions	ISO	RGD:1613887	6480464	[perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PARP14 mRNA	CTD	PMID:36331819
Parp14	Rat	lidocaine	increases expression	EXP		6480464	Lidocaine results in increased expression of PARP14 mRNA	CTD	PMID:35283115
Parp14	Rat	lipopolysaccharide	multiple interactions	ISO	RGD:1613887	6480464	(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of PARP14 mRNA]	CTD	PMID:25890327
Parp14	Rat	lipopolysaccharide	multiple interactions	ISO	RGD:1344897	6480464	[S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PARP14 mRNA	CTD	PMID:35811015
Parp14	Rat	lipopolysaccharide	increases expression	ISO	RGD:1344897	6480464	Lipopolysaccharides results in increased expression of PARP14 mRNA	CTD	PMID:35811015
Parp14	Rat	lipopolysaccharide	increases expression	ISO	RGD:1613887	6480464	Lipopolysaccharides results in increased expression of PARP14 mRNA	CTD	PMID:25890327
Parp14	Rat	manganese atom	increases expression	ISO	RGD:1613887	6480464	Manganese results in increased expression of PARP14 mRNA	CTD	PMID:23499988
Parp14	Rat	manganese(0)	increases expression	ISO	RGD:1613887	6480464	Manganese results in increased expression of PARP14 mRNA	CTD	PMID:23499988
Parp14	Rat	methapyrilene	increases methylation	ISO	RGD:1344897	6480464	Methapyrilene results in increased methylation of PARP14 intron	CTD	PMID:30157460
Parp14	Rat	methidathion	decreases expression	ISO	RGD:1613887	6480464	methidathion results in decreased expression of PARP14 mRNA	CTD	PMID:34813904
Parp14	Rat	methylmercury chloride	multiple interactions	EXP		6480464	[Hydrocarbons, Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of more ...	CTD	PMID:30744511
Parp14	Rat	mono(2-ethylhexyl) phthalate	multiple interactions	ISO	RGD:1613887	6480464	[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PARP14 mRNA	CTD	PMID:36189433
Parp14	Rat	nefazodone	decreases expression	EXP		6480464	nefazodone results in decreased expression of PARP14 mRNA	CTD	PMID:24136188
Parp14	Rat	nickel atom	increases expression	ISO	RGD:1344897	6480464	Nickel results in increased expression of PARP14 mRNA	CTD	PMID:24768652\|PMID:25583101
Parp14	Rat	oxaliplatin	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in increased expression of PARP14 mRNA	CTD	PMID:25729387
Parp14	Rat	ozone	multiple interactions	ISO	RGD:1613887	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ...	CTD	PMID:34911549
Parp14	Rat	paracetamol	decreases expression	ISO	RGD:1344897	6480464	Acetaminophen results in decreased expression of PARP14 mRNA	CTD	PMID:21420995\|PMID:29067470
Parp14	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of PARP14 mRNA	CTD	PMID:32479839\|PMID:33387578
Parp14	Rat	PCB138	multiple interactions	ISO	RGD:1613887	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Parp14	Rat	pentachlorophenol	increases expression	ISO	RGD:1613887	6480464	Pentachlorophenol results in increased expression of PARP14 mRNA	CTD	PMID:23892564
Parp14	Rat	perfluorooctane-1-sulfonic acid	decreases expression	ISO	RGD:1344897	6480464	perfluorooctane sulfonic acid results in decreased expression of PARP14 mRNA	CTD	PMID:27153767
Parp14	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	RGD:1613887	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PARP14 mRNA; [perfluorooctane sulfonic more ...	CTD	PMID:36331819
Parp14	Rat	pirinixic acid	multiple interactions	ISO	RGD:1613887	6480464	[pirinixic acid co-treated with PPARA] results in decreased expression of PARP14 mRNA	CTD	PMID:20813756
Parp14	Rat	pirinixic acid	decreases expression	ISO	RGD:1613887	6480464	pirinixic acid results in decreased expression of PARP14 mRNA	CTD	PMID:17426115\|PMID:20813756\|PMID:23811191
Parp14	Rat	resveratrol	multiple interactions	ISO	RGD:1344897	6480464	[Plant Extracts co-treated with Resveratrol] results in increased expression of PARP14 mRNA	CTD	PMID:23557933
Parp14	Rat	rotenone	decreases expression	EXP		6480464	Rotenone results in decreased expression of PARP14 mRNA	CTD	PMID:28374803
Parp14	Rat	S-(1,2-dichlorovinyl)-L-cysteine	multiple interactions	ISO	RGD:1344897	6480464	[S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of PARP14 mRNA	CTD	PMID:35811015
Parp14	Rat	silicon dioxide	decreases expression	ISO	RGD:1613887	6480464	Silicon Dioxide results in decreased expression of PARP14 mRNA	CTD	PMID:19073995
Parp14	Rat	silver atom	decreases expression	ISO	RGD:1613887	6480464	Silver results in decreased expression of PARP14 mRNA	CTD	PMID:27131904
Parp14	Rat	silver(0)	decreases expression	ISO	RGD:1613887	6480464	Silver results in decreased expression of PARP14 mRNA	CTD	PMID:27131904
Parp14	Rat	sodium arsenite	increases expression	ISO	RGD:1344897	6480464	sodium arsenite results in increased expression of PARP14 mRNA	CTD	PMID:38568856
Parp14	Rat	Soman	increases expression	EXP		6480464	Soman results in increased expression of PARP14 mRNA	CTD	PMID:19281266
Parp14	Rat	sulindac	decreases expression	EXP		6480464	Sulindac results in decreased expression of PARP14 mRNA	CTD	PMID:24136188
Parp14	Rat	sunitinib	decreases expression	ISO	RGD:1344897	6480464	Sunitinib results in decreased expression of PARP14 mRNA	CTD	PMID:31533062
Parp14	Rat	tamoxifen	affects expression	ISO	RGD:1613887	6480464	Tamoxifen affects the expression of PARP14 mRNA	CTD	PMID:20937368
Parp14	Rat	temozolomide	increases expression	ISO	RGD:1344897	6480464	Temozolomide results in increased expression of PARP14 mRNA	CTD	PMID:31758290
Parp14	Rat	testosterone	multiple interactions	EXP		6480464	[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PARP14 mRNA	CTD	PMID:32741896
Parp14	Rat	tetrachloromethane	decreases expression	EXP		6480464	Carbon Tetrachloride results in decreased expression of PARP14 mRNA	CTD	PMID:31150632
Parp14	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of PARP14 mRNA	CTD	PMID:34492290
Parp14	Rat	topotecan	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in increased expression of PARP14 mRNA	CTD	PMID:25729387
Parp14	Rat	trichostatin A	increases expression	ISO	RGD:1344897	6480464	trichostatin A results in increased expression of PARP14 mRNA	CTD	PMID:24935251
Parp14	Rat	triclosan	increases expression	ISO	RGD:1344897	6480464	Triclosan results in increased expression of PARP14 mRNA	CTD	PMID:30510588
Parp14	Rat	Triptolide	increases expression	EXP		6480464	triptolide results in increased expression of PARP14 protein	CTD	PMID:32519852
Parp14	Rat	troglitazone	decreases expression	ISO	RGD:1613887	6480464	troglitazone results in decreased expression of PARP14 mRNA	CTD	PMID:28973697
Parp14	Rat	trovafloxacin	increases expression	ISO	RGD:1613887	6480464	trovafloxacin results in increased expression of PARP14 mRNA	CTD	PMID:35537566
Parp14	Rat	tungsten	decreases expression	ISO	RGD:1613887	6480464	Tungsten results in decreased expression of PARP14 mRNA	CTD	PMID:30912803
Parp14	Rat	urethane	decreases expression	ISO	RGD:1344897	6480464	Urethane results in decreased expression of PARP14 mRNA	CTD	PMID:28818685
Parp14	Rat	valproic acid	multiple interactions	ISO	RGD:1344897	6480464	[Hydralazine co-treated with Valproic Acid] results in increased expression of PARP14 mRNA	CTD	PMID:17183730
Parp14	Rat	valproic acid	affects expression	ISO	RGD:1344897	6480464	Valproic Acid affects the expression of PARP14 mRNA	CTD	PMID:25979313
Parp14	Rat	valproic acid	decreases expression	ISO	RGD:1344897	6480464	Valproic Acid results in decreased expression of PARP14 mRNA	CTD	PMID:23179753
Parp14	Rat	vancomycin	decreases expression	ISO	RGD:1613887	6480464	Vancomycin results in decreased expression of PARP14 mRNA	CTD	PMID:18930951
Parp14	Rat	vinclozolin	decreases expression	EXP		6480464	vinclozolin results in decreased expression of PARP14 mRNA	CTD	PMID:23034163

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Parp14	Rat	biological_process		ND		1598407	03/2018: no relevant rat data	RGD
Parp14	Rat	NAD+ catabolic process	involved_in	ISO	RGD:1613887	1624291	PMID:23956424	RGD	PMID:23956424
Parp14	Rat	negative regulation of DNA-templated transcription	involved_in	IEA	GO:0003714	1600115	GO_REF:0000108	GOC	GO_REF:0000108
Parp14	Rat	negative regulation of gene expression	involved_in	ISO	RGD:1344897	1624291	PMID:27796300	RGD	PMID:27796300
Parp14	Rat	negative regulation of gene expression	involved_in	IBA	PANTHER:PTN004461525\|UniProtKB:Q460N5\|UniProtKB:Q53GL7\|UniProtKB:Q8IXQ6	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Parp14	Rat	negative regulation of gene expression	involved_in	IEA	UniProtKB:Q460N5\|ensembl:ENSP00000418194	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	negative regulation of type II interferon-mediated signaling pathway	involved_in	ISO	RGD:1344897	1624291	PMID:27796300	RGD	PMID:27796300
Parp14	Rat	negative regulation of type II interferon-mediated signaling pathway	involved_in	IEA	UniProtKB:Q460N5\|ensembl:ENSP00000418194	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	negative regulation of type II interferon-mediated signaling pathway	involved_in	ISO	RGD:1613887	1624291	PMID:27796300	RGD	PMID:27796300
Parp14	Rat	negative regulation of type II interferon-mediated signaling pathway	involved_in	IBA	MGI:1919489\|PANTHER:PTN002683692\|UniProtKB:Q460N5	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Parp14	Rat	negative regulation of type II interferon-mediated signaling pathway	involved_in	IEA	UniProtKB:Q2EMV9\|ensembl:ENSMUSP00000037657	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	negative regulation of tyrosine phosphorylation of STAT protein	involved_in	ISO	RGD:1344897	1624291	PMID:27796300	RGD	PMID:27796300
Parp14	Rat	positive regulation of interleukin-4-mediated signaling pathway	involved_in	ISO	RGD:1344897	1624291	PMID:27796300	RGD	PMID:27796300
Parp14	Rat	positive regulation of interleukin-4-mediated signaling pathway	involved_in	IEA	UniProtKB:Q460N5\|ensembl:ENSP00000418194	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	positive regulation of interleukin-4-mediated signaling pathway	involved_in	IEA	UniProtKB:Q2EMV9\|ensembl:ENSMUSP00000037657	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	positive regulation of interleukin-4-mediated signaling pathway	involved_in	ISO	RGD:1613887	1624291	PMID:27796300	RGD	PMID:27796300
Parp14	Rat	positive regulation of tyrosine phosphorylation of STAT protein	involved_in	ISO	RGD:1344897	1624291	PMID:27796300	RGD	PMID:27796300
Parp14	Rat	protein poly-ADP-ribosylation	involved_in	ISO	RGD:1344897,UniProtKB:Q460N5-1	1624291	PMID:16061477	RGD	PMID:16061477

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Parp14	Rat	cytoplasm	located_in	ISO	RGD:1344897	1624291	PMID:27796300	RGD	PMID:27796300
Parp14	Rat	cytoplasm	located_in	IEA	UniProtKB:Q2EMV9\|ensembl:ENSMUSP00000037657	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	cytoplasm	is_active_in	IBA	MGI:1919489\|PANTHER:PTN004461525\|UniProtKB:Q460N5\|UniProtKB:Q53GL7\|UniProtKB:Q8IXQ6	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Parp14	Rat	cytoplasm	located_in	ISO	RGD:1613887	1624291	PMID:23473667	RGD	PMID:23473667
Parp14	Rat	cytoplasm	located_in	IEA	UniProtKB:Q460N5\|ensembl:ENSP00000418194	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	cytosol	located_in	ISO	RGD:1344897\|UniProtKB:Q460N5-6	1624291		RGD	GO_REF:0000052
Parp14	Rat	cytosol	located_in	IEA	UniProtKB:Q460N5\|ensembl:ENSP00000418194	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	nucleus	is_active_in	IBA	PANTHER:PTN004461525\|UniProtKB:Q53GL7\|UniProtKB:Q8IXQ6	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Parp14	Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Parp14	Rat	plasma membrane	located_in	ISO	RGD:1344897\|UniProtKB:Q460N5-6	1624291		RGD	GO_REF:0000052
Parp14	Rat	plasma membrane	located_in	IEA	UniProtKB:Q460N5\|ensembl:ENSP00000418194	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Parp14	Rat	enzyme binding	enables	ISO	RGD:1344897	1624291	UniProtKB:Q8IXQ6 PMID:27796300	RGD	PMID:27796300
Parp14	Rat	enzyme binding	enables	IEA	UniProtKB:Q460N5\|ensembl:ENSP00000418194	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	glycosyltransferase activity	enables	IEA	UniProtKB-KW:KW-0328	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Parp14	Rat	NAD+ binding	enables	ISO	RGD:1344897,UniProtKB:Q460N5-1	1624291	PMID:16061477	RGD	PMID:16061477
Parp14	Rat	NAD+ poly-ADP-ribosyltransferase activity	enables	ISO	RGD:1344897,UniProtKB:Q460N5-1	1624291	PMID:16061477	RGD	PMID:16061477
Parp14	Rat	NAD+ poly-ADP-ribosyltransferase activity	enables	IEA	InterPro:IPR012317	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Parp14	Rat	NAD+ poly-ADP-ribosyltransferase activity	enables	IEA	UniProtKB:Q460N5\|ensembl:ENSP00000418194	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	NAD+ poly-ADP-ribosyltransferase activity	enables	IEA	UniRule:UR000078407	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Parp14	Rat	NAD+ poly-ADP-ribosyltransferase activity	enables	IBA	PANTHER:PTN001025084\|UniProtKB:Q460N3\|UniProtKB:Q460N5\|UniProtKB:Q53GL7	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Parp14	Rat	NAD+ poly-ADP-ribosyltransferase activity	enables	ISO	RGD:1613887	1624291	PMID:22841009	RGD	PMID:22841009
Parp14	Rat	NAD+ poly-ADP-ribosyltransferase activity	enables	ISO	RGD:1344897	1624291	PMID:27796300	RGD	PMID:27796300
Parp14	Rat	NAD+-protein mono-ADP-ribosyltransferase activity	enables	ISO	RGD:1344897	1624291	PMID:18851833, PMID:25043379	RGD	PMID:18851833\|PMID:25043379
Parp14	Rat	NAD+-protein mono-ADP-ribosyltransferase activity	enables	IEA	UniProtKB:Q460N5\|ensembl:ENSP00000418194	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Parp14	Rat	nucleotidyltransferase activity	enables	IEA	UniProtKB-KW:KW-0548	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Parp14	Rat	protein binding	enables	ISO	RGD:1344897	1624291	UniProtKB:Q460N3\|UniProtKB:Q53GL7 PMID:23473667	RGD	PMID:23473667
Parp14	Rat	protein binding	enables	ISO	RGD:1613887	1624291	UniProtKB:P06745\|UniProtKB:P52633\|UniProtKB:Q53GL7 PMID:16537510, PMID:17875708, PMID:23473667	RGD	PMID:16537510\|PMID:17875708\|PMID:23473667
Parp14	Rat	transcription corepressor activity	enables	IBA	PANTHER:PTN004461525\|UniProtKB:Q460N3\|UniProtKB:Q8IXQ6	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Parp14	Rat	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Pathway Annotations Click to see Annotation Detail View

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Parp14	Rat	ADP-ribosylation pathway, mono and poly-ribosylation		ISO	RGD:1344897	11100038		RGD

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Parp14	Rat	interleukin-4 signaling pathway		ISO	RGD:1344897	6484113		PID	PID:200022

Disease Annotations Click to see Annotation Detail View

alkaptonuria (ISO)

familial hypocalciuric hypercalcemia (ISO)

Primary Lymphedema with Myelodysplasia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-alpha-phellandrene (ISO)

(1->4)-beta-D-glucan (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (EXP,ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (EXP,ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2,4,6-tribromophenol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (EXP)

5-fluorouracil (ISO)

acetamide (EXP)

aconitine (EXP)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-phellandrene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

buspirone (EXP)

cadmium dichloride (EXP)

carbon nanotube (ISO)

chlorohydrocarbon (EXP)

chromium(6+) (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

clofibrate (ISO)

cobalt dichloride (EXP)

Cuprizon (EXP)

D-glucose (ISO)

decabromodiphenyl ether (ISO)

dioxygen (EXP,ISO)

diquat (ISO)

endosulfan (EXP)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenthion (ISO)

finasteride (EXP)

flutamide (EXP)

fructose (ISO)

fulvestrant (ISO)

furan (EXP)

gentamycin (EXP)

glucose (ISO)

glycidol (EXP)

glyphosate (ISO)

hydralazine (ISO)

inulin (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

methapyrilene (ISO)

methidathion (ISO)

methylmercury chloride (EXP)

mono(2-ethylhexyl) phthalate (ISO)

nefazodone (EXP)

nickel atom (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

pentachlorophenol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

resveratrol (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

Soman (EXP)

sulindac (EXP)

sunitinib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

topotecan (EXP)

trichostatin A (ISO)

triclosan (ISO)

Triptolide (EXP)

troglitazone (ISO)

trovafloxacin (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

NAD+ catabolic process (ISO)

negative regulation of DNA-templated transcription (IEA)

negative regulation of gene expression (IBA,IEA,ISO)

negative regulation of type II interferon-mediated signaling pathway (IBA,IEA,ISO)

negative regulation of tyrosine phosphorylation of STAT protein (ISO)

positive regulation of interleukin-4-mediated signaling pathway (IEA,ISO)

positive regulation of tyrosine phosphorylation of STAT protein (ISO)

protein poly-ADP-ribosylation (ISO)

Cellular Component

cytoplasm (IBA,IEA,ISO)

cytosol (IEA,ISO)

nucleus (IBA,IEA)

plasma membrane (IEA,ISO)

Molecular Function

enzyme binding (IEA,ISO)

glycosyltransferase activity (IEA)

NAD+ binding (ISO)

NAD+ poly-ADP-ribosyltransferase activity (IBA,IEA,ISO)

NAD+-protein mono-ADP-ribosyltransferase activity (IEA,ISO)

nucleotidyltransferase activity (IEA)

protein binding (ISO)

transcription corepressor activity (IBA)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ADP-ribosylation pathway, mono and poly-ribosylation (ISO)

interleukin-4 signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.	Barkauskaite E, etal., Mol Cell. 2015 Jun 18;58(6):935-46. doi: 10.1016/j.molcel.2015.05.007.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:16061477	PMID:18851833	PMID:19946888	PMID:23473667	PMID:25043379	PMID:27796300

Genomics

Comparative Map Data

Parp14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	78,408,134 - 78,440,201 (+)	NCBI		GRCr8
mRatBN7.2	11	64,902,848 - 64,934,916 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	64,902,785 - 64,934,916 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	73,724,829 - 73,756,951 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	66,387,099 - 66,419,216 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	65,418,357 - 65,450,473 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	68,105,442 - 68,137,509 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	68,105,369 - 68,137,535 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	71,194,913 - 71,226,980 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	66,736,902 - 66,768,977 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	66,800,714 - 66,824,843 (+)	NCBI
Celera	11	64,365,191 - 64,397,200 (+)	NCBI		Celera
Cytogenetic Map	11	q22	NCBI

PARP14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	122,680,839 - 122,730,840 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	122,680,839 - 122,730,840 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	122,399,686 - 122,449,687 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	123,882,362 - 123,932,377 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	123,900,859 - 123,932,376	NCBI
Celera	3	120,809,505 - 120,859,520 (+)	NCBI		Celera
Cytogenetic Map	3	q21.1	NCBI
HuRef	3	119,772,932 - 119,822,958 (+)	NCBI		HuRef
CHM1_1	3	122,363,227 - 122,413,244 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	125,400,088 - 125,450,091 (+)	NCBI		T2T-CHM13v2.0

Parp14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	35,652,262 - 35,691,904 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	35,653,244 - 35,691,914 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	35,831,892 - 35,871,518 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	35,832,874 - 35,871,544 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	35,832,964 - 35,871,468 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	35,752,625 - 35,791,247 (-)	NCBI		MGSCv36	mm8
Celera	16	36,312,784 - 36,351,557 (-)	NCBI		Celera
Cytogenetic Map	16	B3	NCBI
cM Map	16	25.43	NCBI

Parp14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955427	21,879,740 - 21,927,883 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955427	21,878,980 - 21,929,097 (+)	NCBI	ChiLan1.0	ChiLan1.0

PARP14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	120,630,429 - 120,680,952 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	120,635,379 - 120,685,731 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	119,773,334 - 119,823,732 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	126,677,868 - 126,728,256 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	126,677,868 - 126,728,256 (+)	Ensembl	panpan1.1		panPan2

PARP14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	25,763,282 - 25,798,284 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	25,763,255 - 25,798,198 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	25,787,251 - 25,824,358 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	25,996,942 - 26,033,819 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	25,996,843 - 26,031,731 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	25,794,923 - 25,831,746 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	25,836,951 - 25,874,257 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	26,396,287 - 26,433,388 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101962583
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	128,548,280 - 128,598,605 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936536	8,923,411 - 8,974,283 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936536	8,923,398 - 8,976,583 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PARP14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	137,809,510 - 137,865,106 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	137,809,499 - 137,865,383 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	147,430,086 - 147,483,561 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PARP14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	58,135,092 - 58,185,988 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	58,134,973 - 58,185,521 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	108,163,757 - 108,215,859 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Parp14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624912	969,236 - 1,023,564 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624912	969,144 - 1,022,506 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Parp14
452 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	262
Count of miRNA genes:	161
Interacting mature miRNAs:	206
Transcripts:	ENSRNOT00000046888
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	59802794	82566553	Rat
70180	BpQTLcluster10	Blood pressure QTL cluster 10	3.19		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	11	34918041	79918041	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	45459323	75190161	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	19456205	76331918	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	22959403	67959403	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	60346590	86241447	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	31239134	78851519	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	40946188	82566702	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	44285759	82566702	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	27672410	82846715	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	23280456	68280456	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	54457534	86241447	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	23280456	68280456	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	55136729	82993457	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	56351424	86241447	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	59802794	82566545	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	29528418	82566702	Rat

Markers in Region

AA955471

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	64,933,474 - 64,933,654 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	68,136,068 - 68,136,247	NCBI	Rnor6.0
Rnor_6.0	11	67,864,444 - 67,864,623	NCBI	Rnor6.0
Rnor_5.0	11	71,225,539 - 71,225,718	UniSTS	Rnor5.0
Rnor_5.0	11	70,952,692 - 70,952,871	UniSTS	Rnor5.0
RGSC_v3.4	11	66,767,536 - 66,767,715	UniSTS	RGSC3.4
Celera	11	64,395,759 - 64,395,938	UniSTS
RH 3.4 Map	11	462.31	UniSTS
Cytogenetic Map	11	q22	UniSTS

RH141648

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	64,934,557 - 64,934,759 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	68,137,151 - 68,137,352	NCBI	Rnor6.0
Rnor_6.0	11	67,865,527 - 67,865,728	NCBI	Rnor6.0
Rnor_5.0	11	71,226,622 - 71,226,823	UniSTS	Rnor5.0
Rnor_5.0	11	70,953,775 - 70,953,976	UniSTS	Rnor5.0
RGSC_v3.4	11	66,768,619 - 66,768,820	UniSTS	RGSC3.4
Celera	11	64,396,842 - 64,397,043	UniSTS
RH 3.4 Map	11	462.8	UniSTS
Cytogenetic Map	11	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC090003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000046888 ⟹ ENSRNOP00000046194

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	64,902,848 - 64,934,916 (+)	Ensembl
Rnor_6.0 Ensembl	11	68,105,369 - 68,137,535 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103796 ⟹ ENSRNOP00000081888

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	64,902,785 - 64,934,916 (+)	Ensembl

RefSeq Acc Id:

NM_001191659 ⟹ NP_001178588

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	78,408,134 - 78,440,201 (+)	NCBI
mRatBN7.2	11	64,902,848 - 64,934,916 (+)	NCBI
Rnor_6.0	11	68,105,442 - 68,137,509 (+)	NCBI
Rnor_5.0	11	71,194,913 - 71,226,980 (+)	NCBI
Celera	11	64,365,191 - 64,397,200 (+)	NCBI

Sequence:

show sequence

ATGGCAGCGTCGGGTCCCTTCCCGCTGCTGGTCGAGGGCTCTTGGGGTCCCGACCCCCCGAAGA
ACTTGATCAACAAGTTGCAAATGTACTTCCAGAGCCGGAAGAAATCTGGAGGAGGGGAGTGCGA
GGTCGTCCCGGAGCCCGGGAACCCAGCACGCTTCCTGGTGCTCTTCTCCCCGGAGGATGTTCGG
CAGAATGTTCTGGAGAAAGAGAATCATGAGTTAGTGTGGCAAGGAAAAGGAACATTCAAAATGA
CCGTCCAGTTGCCCGCAGACCCAGGGCAAGCCTCAGTCTCTAAGAAGGCAATTCCAGAAGAGGA
GTCCAAGACAAAAGAAGATGCTGTGAAACCAGGTGATTTGGACACAACACCTTCTCCCAGCAGC
AGATCAGAAGAAATGGAAGATGTCCCAAAAGAATGTGAAAATATTTCCTCCATGGTGGCATTTG
AACAACTGCCCGAGAAAGTATCGGAGATGGTGCTGACCTTCCTGGTGGAGAATATAAGTGGCCT
CCCTAGTGATGATTTTAAGGTGGAATTGATCCGAGATTTCGCTGTTGCTGTGGTTACCTTTCAG
AAGCCTATAGATACCAAAAAATTTATTATTGATTGTATCAGCCACCGCTCAAATCAACAACTCC
AACTTGTCCCGAGACTTCTGGAAACGACCAATGTAGTGAGGGTGGAGAACCTGCCTCCTGGGGT
GGATGATTACCAGCTGCAACTCTTCTTTGAAAACCCTTTCAACGGGGGTGGTAGGGTCGCCCGA
GTTGAGTGTTTCCCCGAAGAGAGTTCGGCGCTGGTTGAGTTTTGTGACAGCAAAGTGTTAGACA
CCATTATGGCCAAGAAACACAGTTTCAACAAGATGCCGCTGTCTGTCTTCCCATATTACCCCTC
CCTGGGCACAGCCTTGTATGGTGAGGAGAAGCCTCTGGTCAAGCTTCCAGCATCTTTCCAGGAG
TCCCTGGATCTTCCTTTGTGGAAGTTCTTTCAGAAAAATGATCATCTGATGGAGGAGATAAATG
ATGAAATGAGGCACTGTCACTGCGAGCTGACGTGGTCTGAAATCAACGGTAAACTGACCGTCAG
ACCGGCCGCCACCTTAGTCAGTCACAGACCGAGCATCAAGACCTGGCAGAGGGATGCGTCCGCA
GCACTCTCTGGCATCAGGTCTAAATATGATGTGATGGTGTTTGAAGTGTGCTCGCCAGTATGGG
ACATCATAAAGCATGAGTTAGGAGATGACAGGGTTTTGATTGAGTTTGAGAAGGAGAGTCTGAA
TGTAGCAGGAAAATCAGAAGATGTCCAAGGCATTAGCCAGCAAATCAGGGAACTAATAGAGCGC
ACCACTGAAAAGCTCAGAAGGGAAGAGCAGAGTCTGGAGGAGAAAGTGGCCATTTCCTCGGGAA
AGCATTTTCTTCTGTACCACAGTGGCTTCCTGAAGGATCTAAGCAAAGAGTACCCGGAGATGGA
GATCTCTTACGATGCCACGGCTCAGTACCTGTGCATTAAAGGCCTCCGTGCAGATGTGTACAAA
GTAAAGTGTGAAATCCAAGAAAAGGTGTTTTCCATGGCTCAGAAAAATGTCCCGGTTTCTTCCG
AAGTCTTCAGATTTCTGCAGCAAGTAGACGGTCAGAGACTCTCCAATGCTCTGTTCAAGGCTCA
GAACATTCTTGCCACATACGAGCTGAAAGATAACGCTCTTTTCTTAATTGGAAGTTCTCCCAAA
GATCTGGCAGAAGCTGAGGCCAAAATGCTCAGTGCTTTAAGTCATAAGCACATTGAAGTTGAGG
ACAAGGAAGTTCTGAGAAGTAATGTGTGGAAGAAGAAAATTCACCCTCTGCAAAAGAGACACGG
CTCCTACGCAGCCATTATGGTCAAGAATGAGTTGACGTCGGGAGTCCCGGCTGAGGTCGTCATC
GCCGGCTGTGTGAAAGAAGTCAATGAAATTCATAGGCAGCTTTTCGAGTTTTTGGAAAACCACA
TGAAAGTTGAAAGAGTGGTCAAAATCGATCCACCCTTGATTATTGACTATTTAAAGACAGACAA
GAGGCTACTGTCAAAGACAAAGAAGGCAAATGTGAGTGTGAGTTTCAAGACTAAAGATGATCCA
AACAGCATTTTGTTACTTGGCTCCAAGAGCAAAGTTCTAGAGTGCCTGGATACAGTCAAGGAAA
TCCGGGATTCAGTCTGCGTCAGAAAATTCCAGACTGACAAAGCCGGTGCCAGGCACTTCTTCCA
GGATAAAGAATTCTATTACAAAATGGAGATCAGACGTCTGTATGGATGCATCGTTGAACTGAAG
GAGGGTGAAGAGGGGGAGGAAGACAGCCTTAAGGAGCAGAAGTGCTACTTACAGAGGGACATAG
GCCCTGGGGTTACACTGATTGTCCACGAGGGAGACCTGAGTCTGTTTCCTGTTGATGTGGTAGT
GAACGCAGCCAATGAGAGCCTTAAGCACATCGATGGCCTCGCGGGCACTCTCTCAAAGGCTGCG
GGCCCCAGCCTCCAAGCAGAATGTGACCTGATCGTGAAAAAGGGAGGCATGGTCCCACCCGGCA
ATGCTGTTATCTCAAAAGCAGGCAAGCTCCCTTGTCGTTATGTCATCCATGCCGTAGGGCCTCG
ATGGAAGGGAGATAAGGTCCTGGAGTGTGTGAACCTCCTGAAGAAAGCTGTGAAACAAAGTCTC
ACTTTAGCTGAAGAGTACAAGTGCCAGTCCATAGCCATACCAGCGATCAGCTCTGGGATCTTTG
ATTTTCCCTTAGACCTGTGCGTGGCATCCATTGCTTCAGCCATCAAGGACAACGTCCAACAGAA
GCAGAACACGCACTCCGTGAAAAAGATTTATCTGGTGGACGTATCTGCAAAGGTTGCCAAGGCC
TTTGCTGAAGCTGTCAAGACTACATATAGAGATATCCTTTCTCCAGCCAGTGTTAAAGCATTAG
TACCACCTGGGAAAATGCCCCAGAAGCAAGGCAAGCTGCTGGTGTCACCAGAAGGCTTGAACAT
CCGCCTGATTGAAGAAGGTGTGCAGAATGCTGAGGCCCATGCCATTGTGAACTCTGTTTCCTCG
GATCTTATACTCAACAAAGGACCCCTTTCTCAGGCTTTCTTGGAAAGTGCTGGGCCAGAACTCC
AGGAGGAATTGACCAAGGCAGGACAAGGGGTCTCTGTCAGTGTGGGTACAGTTCTTCAAACCAG
CGGCTGTAATCTGAACAGCCGCTCCATCTTCCACGTGGTGACCCCACCATGGAAAAGCAACAAC
AGCGAGTGGTCACTAAAGATCATGAAAAACATCATCCGTGACTGTCTGAGGACCACCGAGGACC
TGTCTCTACAATCCATTGCATTTCCAGCAATAGGAACGGGAAATCTGGGGTTTCCTAAACCCGA
ATTTGCTAAATTGATAATTTCAGAAGTACTCAAATTCAGTAGCAGGAACCAACTGAAGACTTTA
CAAGAGGTTCAGTTTCTGCTGCACCCCAAGGACCATGAAAACATTCAGGCATTTTTAGATGAAT
TTGACAAAAGGAGTAATGGAGATCCTAGTAGCAAGAATCCCAAGGCTGAAGACACACAAGGTAT
CTATGGGAGTCTTTCCAGCCCTACTTTAGGAGTGCATGAGATGAATATTGGCCCGATCCTCTTC
CAAGTGGCCACCGGGGACATCATCAAAGAAGTGGCAGATGTGATTGTCAATTCCACATCATGCA
CGTTTAATCTCAAATCAGGGGTCTCCAAAGCAATTTTGGAAGGTGCAGGACAAAATGTGGAGCA
AGAGTGTTCTCGCTTGGCTCAACAGGGTAAAGAGTACATAGTCACTGGAGGTGGATTATTGAAA
TGTAAGAGTATTATTCATGTTGATGGTGGGAATGATGTCAAGAGATCAGTTTCCTGTATTTTGG
AAGAATGTGAACAACGCAGTTTCTCATCCATTTGTCTACCAGCTATTGGCACAGGAAGCGCTCA
ACAGGATCCAAAGGTAGTAGCAAAAGCGGTATTGGATGCCATTGAAGAATTTGTCCAGAAGAAA
TCAGTGCAGGCTGTGAAGAGAGTTAAAGTTGTTATCTTCCAGCCCCATATTCTGCAATTTTTCT
ATGACAACATGAAAGAAAGAGAAGGTTCTCCAGCTCCTGTCAAGCCGTCAGTGATGTCTAAGAT
TGCCTCCTTCCTTGGCTTTCCAACACAAGCTTCACCCCCAAAGAACACCCTGGTTTTGGAAAAG
AAAATTGAGCTCACAGTTTTCCAGATATGTGGCCCAGGTGTAGACAGTGTGGAAGGTACAATCT
CCTGGCTAAAGAGTCTGATTACCAAAGAGCAGTTTTCCTTCACCAATGAGGACGAGTGTGTCAG
AGACTTTGACACCGAGGAGTACAGGAAACTGAATGAGATGCAGAAGAGGCTGAACATCATCATT
GAGCTGAACCAGAAGAAACCTTTGATTAAAGTCTCAGGAATCAGCAGAGACGTGGTAGAAGCTA
GAGATGAGATTGACAACATGGTCAAGAGCATTAGATTGGCTAAGGAAAAGGAAAACCAGGCAGA
CTACGTCTCTACATTTGTGGAATGGCAATATATTGCTAATAACACCACACGGTGTTTTGACAAG
ATAGCCAACATGCAGTTGGAGGATGCATGGAAGGCAAAGAAGAAGCACACTGTTGTCAAAATTC
AGAATCAGGACTTCACGGTGGACTTGAGCACAAACACAGCCACGGCTCCCCAAGGACTGAGTTT
CACTGTCCAGCGACTCCTCAAAGCTGAAGCTGAAATTCCTGCCAATTGGAGTGATATGAAGCAG
AACAAATTGCTTGTGGTGAGTCTGCAAACCAGTGATGCCGAGTACACCATGGTATCCAGGGCCT
TCCATCAGACCTGCCCAAACTTTGTCATAGAGAAGATTGAAAGGATTCAAAATCCAGCTCTTTG
GAGGAGGTACCAGGCGTACAAAAAAATTATGGATGAAAAGAATGGCAATGTGATAAATGAGAAG
CAACTCTTCCATGGGACGGAGTTTGGCTCTCTGGCACAGCTCAACAGTAATGGATTTAACCGCA
GCTATGCTGGGAAGAACGCTACAGCCTATGGGAAAGGAACCTATTTTGCAGTCAATGCTTCCTA
TTCTGCCCATGACACATATTCCAAACCAGATGCCAATGGGAAAAAGTATATGTATTATGTGCGG
GTCCTCACTGGAAACTACACACAAGGAAACGCATCACTGATTGTGCCTCCTTCAAGGGACCCTC
AAAATGCTACTGACTTGTTTGACACTGTCGCAGATAATGTTATAAATCCGAGTATATTTGTAGT
GTTTTATGACAATCAAGCATACCCTGAGTATCTTATCACATTTAGGAAGTAACACTTTGGGGTG
CCTTCTGAAAGACATTGGTATCTGCCGTAGGACAAATTTTAGCTGTTTTCCTTCTTAGACTTTC
TTCTCTAAGAGCACGAGGTCTTTCTCTGCCACGGATTGTTTCCTCAGCTGCCCCTTCATAGTGA
ACATGAACCTACTTGAGAGCCAACCACTTGAGAATTTCAAGCAGGTGACAGCTTTAACTGCCTT
CACAAATGTGAACCTCAAATCCACGGAAAAGAACAAACTTACGTTCTGGAAGGACAATAAAACC
TTTATGCACTTTCAGAAAGCCCACAATACACCCACCACCAGTGGAGTTACATCAGAGCACCACT
GTGCTGAGGGGCACCCAGGACCACTGAGCCAGTAAGGCTGCCAACTGAACAGATTCCAAGACAG
AGAACTTCGTTCATCACTAACAGCGCCGTGTCCTGTGGGTTGGACAGTTCCAGCCAGGGTTATG
TACAGACTGGGTTCTGGGATGTGGCTCTGGGTCTGTGTGAACTGAGCCCCCCAAGGAGAGGCAC
AGCTGAAGCCCTGTCAGGGGGCCCTTTTAATGTTGACACCAATGTTGAGGCTACCTAGTGAAGA
AATGGGATGGGGCCTGCTACCTCTCCCATGGAAGTCCTTCTACTGGGTGAAAATGAATGAACTC
TAACAGTATTGGCTAGCGTCTTTCTTGTGGCAGGCTGGCTTGTGATAACTTGAAGCTTTATGAC
TAAGTCAGTCATTTTGCTAACTCACTAACAGTATCTACTGGATGCGATTTGTTTCTTGTGATGC
CAGAGATCACCCAGAGCCTCACATGGGCCAGGCAAGCACTCTACTACTGAACTATATTCCCAGC
CTTTTAGTGAGGCAAGACTCCACTAAGTTGCCCTGGCAGGTTTGAACTCATTATCTTCCTGCAT
TGGCTACTTATTGGGGTGGGGTGGGGTGCTTAAATTGTTCTTTTAATTTTCTCCTGTACTCCCA
TTTATTGAGTGCCTGGACCCTTGTCAGGTAGAATAAGAGGTGTGTTCACATAGATAATTTTGTT
TCCATAAAAAAAAATGCACTGTAAGAATTATGTCAAGGCCTAGGAGCAGGCTCAGAGTACAAGA
GCTGTCCTTGCCAAAGGTCACTAAGGCAGGAACCGCAGAGCCAGCCACCAGAGTCTTGGTACTG
GGTTGAGCCCCTCACTATTCCCAGCACAGAGCCTGGCCCTGAGGTAAGCCTGTGCTGCTTCAGA
AGTTGGCTTTTCTCCTTCTGGGATTGGTGTCCACTCTGCCCCTTTTCTAGGTCATGGAGCTAGT
GCGGTGTAATGTTCCCAGGAGGTAGGTACACTCTTAGGTGTTGTGGGGATCCAAGTGCTGGTTC
CCACCATTGGCATTAACAGTGGACTGCAAGCAGAGAGAGGGGTCCCCATCATTGTTTCGTGGAC
ACTGAGGCCTTGAGACCTTGGCTGCTGTGTCTATGTGGACTGGCAAAGACTGTGGCTTGGGAGG
GGCTTCCTCAGCACTGGCACCTGAACTCAGCACCAAGGATGGCCCCAAGAGGCTTGTTTTCATT
TGCCTTTGTTCTCCAGTGCTTTGGTTACCTCAGGGCAGGGCTGAACAATAGTGTGATGTTACAT
TGAAGAATAAAGACCCAACCAACAAATGTTAGTGTCATTTTCAGTCTAAGTAAATAAGCCATTA
TGTCATTTCCCTTACTTCCTAGTAAAGTTATGTAATTACATAATGTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001178588	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000046194
	ENSRNOP00000046194.5
	ENSRNOP00000081888.1

RefSeq Acc Id:

NP_001178588 ⟸ NM_001191659

- UniProtKB:

F1LZ05 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAASGPFPLLVEGSWGPDPPKNLINKLQMYFQSRKKSGGGECEVVPEPGNPARFLVLFSPEDVR
QNVLEKENHELVWQGKGTFKMTVQLPADPGQASVSKKAIPEEESKTKEDAVKPGDLDTTPSPSS
RSEEMEDVPKECENISSMVAFEQLPEKVSEMVLTFLVENISGLPSDDFKVELIRDFAVAVVTFQ
KPIDTKKFIIDCISHRSNQQLQLVPRLLETTNVVRVENLPPGVDDYQLQLFFENPFNGGGRVAR
VECFPEESSALVEFCDSKVLDTIMAKKHSFNKMPLSVFPYYPSLGTALYGEEKPLVKLPASFQE
SLDLPLWKFFQKNDHLMEEINDEMRHCHCELTWSEINGKLTVRPAATLVSHRPSIKTWQRDASA
ALSGIRSKYDVMVFEVCSPVWDIIKHELGDDRVLIEFEKESLNVAGKSEDVQGISQQIRELIER
TTEKLRREEQSLEEKVAISSGKHFLLYHSGFLKDLSKEYPEMEISYDATAQYLCIKGLRADVYK
VKCEIQEKVFSMAQKNVPVSSEVFRFLQQVDGQRLSNALFKAQNILATYELKDNALFLIGSSPK
DLAEAEAKMLSALSHKHIEVEDKEVLRSNVWKKKIHPLQKRHGSYAAIMVKNELTSGVPAEVVI
AGCVKEVNEIHRQLFEFLENHMKVERVVKIDPPLIIDYLKTDKRLLSKTKKANVSVSFKTKDDP
NSILLLGSKSKVLECLDTVKEIRDSVCVRKFQTDKAGARHFFQDKEFYYKMEIRRLYGCIVELK
EGEEGEEDSLKEQKCYLQRDIGPGVTLIVHEGDLSLFPVDVVVNAANESLKHIDGLAGTLSKAA
GPSLQAECDLIVKKGGMVPPGNAVISKAGKLPCRYVIHAVGPRWKGDKVLECVNLLKKAVKQSL
TLAEEYKCQSIAIPAISSGIFDFPLDLCVASIASAIKDNVQQKQNTHSVKKIYLVDVSAKVAKA
FAEAVKTTYRDILSPASVKALVPPGKMPQKQGKLLVSPEGLNIRLIEEGVQNAEAHAIVNSVSS
DLILNKGPLSQAFLESAGPELQEELTKAGQGVSVSVGTVLQTSGCNLNSRSIFHVVTPPWKSNN
SEWSLKIMKNIIRDCLRTTEDLSLQSIAFPAIGTGNLGFPKPEFAKLIISEVLKFSSRNQLKTL
QEVQFLLHPKDHENIQAFLDEFDKRSNGDPSSKNPKAEDTQGIYGSLSSPTLGVHEMNIGPILF
QVATGDIIKEVADVIVNSTSCTFNLKSGVSKAILEGAGQNVEQECSRLAQQGKEYIVTGGGLLK
CKSIIHVDGGNDVKRSVSCILEECEQRSFSSICLPAIGTGSAQQDPKVVAKAVLDAIEEFVQKK
SVQAVKRVKVVIFQPHILQFFYDNMKEREGSPAPVKPSVMSKIASFLGFPTQASPPKNTLVLEK
KIELTVFQICGPGVDSVEGTISWLKSLITKEQFSFTNEDECVRDFDTEEYRKLNEMQKRLNIII
ELNQKKPLIKVSGISRDVVEARDEIDNMVKSIRLAKEKENQADYVSTFVEWQYIANNTTRCFDK
IANMQLEDAWKAKKKHTVVKIQNQDFTVDLSTNTATAPQGLSFTVQRLLKAEAEIPANWSDMKQ
NKLLVVSLQTSDAEYTMVSRAFHQTCPNFVIEKIERIQNPALWRRYQAYKKIMDEKNGNVINEK
QLFHGTEFGSLAQLNSNGFNRSYAGKNATAYGKGTYFAVNASYSAHDTYSKPDANGKKYMYYVR
VLTGNYTQGNASLIVPPSRDPQNATDLFDTVADNVINPSIFVVFYDNQAYPEYLITFRK

hide sequence

Ensembl Acc Id:

ENSRNOP00000046194 ⟸ ENSRNOT00000046888

Ensembl Acc Id:

ENSRNOP00000081888 ⟸ ENSRNOT00000103796

Protein Domains

Macro PARP catalytic

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LZ05-F1-model_v2	AlphaFold	F1LZ05	1-1787	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698188

Promoter ID:

EPDNEW_R8712

Type:

multiple initiation site

Name:

Parp14_1

Description:

poly (ADP-ribose) polymerase family, member 14

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	68,105,413 - 68,105,473	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310490	AgrOrtholog
BioCyc Gene	G2FUF-21204	BioCyc
Ensembl Genes	ENSRNOG00000023334	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000046888	ENTREZGENE
	ENSRNOT00000046888.6	UniProtKB/TrEMBL
	ENSRNOT00000103796.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
	3.30.720.50	UniProtKB/TrEMBL
	3.40.220.10	UniProtKB/TrEMBL
	3.90.228.10	UniProtKB/TrEMBL
InterPro	A1pp	UniProtKB/TrEMBL
	Macro_dom-like	UniProtKB/TrEMBL
	Mono-ARTD/PARP	UniProtKB/TrEMBL
	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	PARP14_WWE	UniProtKB/TrEMBL
	Poly(ADP-ribose)pol_cat_dom	UniProtKB/TrEMBL
	WWE_dom_sf	UniProtKB/TrEMBL
NCBI Gene	303903	ENTREZGENE
PANTHER	PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN	UniProtKB/TrEMBL
	PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP14	UniProtKB/TrEMBL
Pfam	Macro	UniProtKB/TrEMBL
	PARP	UniProtKB/TrEMBL
	WWE_1	UniProtKB/TrEMBL
PhenoGen	Parp14	PhenoGen
PROSITE	MACRO	UniProtKB/TrEMBL
	PARP_CATALYTIC	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000023334	RatGTEx
SMART	A1pp	UniProtKB/TrEMBL
Superfamily-SCOP	ADP-ribosylation	UniProtKB/TrEMBL
	SSF117839	UniProtKB/TrEMBL
	SSF52949	UniProtKB/TrEMBL
UniProt	A0A8I5ZTF7_RAT	UniProtKB/TrEMBL
	F1LZ05	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-27	Parp14	poly (ADP-ribose) polymerase family, member 14	RGD1310490_predicted	similar to hypothetical protein MGC29390 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1310490_predicted	similar to hypothetical protein MGC29390 (predicted)	LOC303903_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC303903_predicted	similar to hypothetical protein MGC29390 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - PID (archival)