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Gene: Map3k14 (mitogen-activated protein kinase kinase kinase 14) Rattus norvegicus

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Symbol:

Map3k14

Name:

mitogen-activated protein kinase kinase kinase 14

RGD ID:

1310487

Description:

Enables protein kinase activity. Involved in protein phosphorylation. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 112. Orthologous to human MAP3K14 (mitogen-activated protein kinase kinase kinase 14); PARTICIPATES IN nuclear factor kappa B signaling pathway; apoptotic cell death pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-phenylprop-2-enal; acrolein.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC360640

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	88,665,417 - 88,715,669 (-)	NCBI		GRCr8
mRatBN7.2	10	88,165,349 - 88,215,558 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	88,165,351 - 88,215,523 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	93,201,107 - 93,251,268 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	92,668,001 - 92,718,220 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	88,061,351 - 88,111,570 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	91,303,428 - 91,353,601 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	91,303,428 - 91,353,601 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	91,074,396 - 91,121,436 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	92,406,098 - 92,456,276 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	92,421,198 - 92,444,501 (-)	NCBI
Celera	10	86,866,471 - 86,916,375 (-)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

JBrowse:

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Model

Annotation Click to see Annotation Detail View

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	hereditary breast ovarian cancer syndrome		ISO	RGD:1321416	8554872	ClinVar Annotator: match by term: Breast-ovarian cancer, familial, susceptibility to, 1	ClinVar	PMID:38922859
Map3k14	Rat	immunodeficiency 112		ISO	RGD:1321416	8554872	ClinVar Annotator: match by term: Immunodeficiency 112 \| ClinVar Annotator: match by term: MAP3K14-related condition	ClinVar	PMID:25406581\|PMID:25741868\|PMID:28492532\|PMID:29230214\|PMID:34093558

Imported Disease Annotations - MGI

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	primary biliary cholangitis		ISS	RGD:1321417	13592920	OMIM:109720 \| OMIM:613007 \| OMIM:613008 \| OMIM:614220 \| OMIM:614221	MouseDO
Map3k14	Rat	Sjogren's syndrome		ISS	RGD:1321417	13592920	OMIM:270150	MouseDO

Imported Disease Annotations - OMIM

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	immunodeficiency 112		ISO	RGD:1321416	7240710		OMIM

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	(-)-epigallocatechin 3-gallate	decreases expression	ISO	RGD:1321416	6480464	epigallocatechin gallate results in decreased expression of MAP3K14 mRNA	CTD	PMID:12628509
Map3k14	Rat	1'-acetoxychavicol acetate	multiple interactions	ISO	RGD:1321416	6480464	1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of MAP3K14 protein]	CTD	PMID:15905586
Map3k14	Rat	1,2-dichloroethane	increases expression	ISO	RGD:1321417	6480464	ethylene dichloride results in increased expression of MAP3K14 mRNA	CTD	PMID:28960355
Map3k14	Rat	17beta-estradiol	increases expression	ISO	RGD:1321416	6480464	Estradiol results in increased expression of MAP3K14 mRNA	CTD	PMID:31614463
Map3k14	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:1321417	6480464	Tetrachlorodibenzodioxin results in increased expression of MAP3K14 mRNA	CTD	PMID:12167310
Map3k14	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of MAP3K14 mRNA	CTD	PMID:33387578
Map3k14	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1321417	6480464	Tetrachlorodibenzodioxin affects the expression of MAP3K14 mRNA	CTD	PMID:21570461
Map3k14	Rat	2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid	decreases activity	ISO	RGD:1321416	6480464	anacardic acid results in decreased activity of MAP3K14 protein	CTD	PMID:18349320
Map3k14	Rat	2-hydroxyethyl methacrylate	increases expression	ISO	RGD:1321416	6480464	hydroxyethyl methacrylate results in increased expression of MAP3K14 mRNA	CTD	PMID:30497689
Map3k14	Rat	2-palmitoylglycerol	increases expression	ISO	RGD:1321416	6480464	2-palmitoylglycerol results in increased expression of MAP3K14 mRNA	CTD	PMID:37199045
Map3k14	Rat	3-isobutyl-1-methyl-7H-xanthine	multiple interactions	ISO	RGD:1321416	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...	CTD	PMID:28628672
Map3k14	Rat	3-phenylprop-2-enal	decreases phosphorylation	EXP		6480464	cinnamaldehyde results in decreased phosphorylation of MAP3K14 protein	CTD	PMID:17486422
Map3k14	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	RGD:1321417	6480464	bisphenol S results in decreased expression of MAP3K14 mRNA	CTD	PMID:39298647
Map3k14	Rat	4-nitrophenol	decreases expression	ISO	RGD:1321417	6480464	4-nitrophenol results in decreased expression of MAP3K14 mRNA	CTD	PMID:34673133
Map3k14	Rat	acrolein	affects expression	EXP		6480464	Acrolein affects the expression of MAP3K14 mRNA	CTD	PMID:38090360
Map3k14	Rat	acrylamide	increases expression	ISO	RGD:1321416	6480464	Acrylamide results in increased expression of MAP3K14 mRNA	CTD	PMID:32763439
Map3k14	Rat	aflatoxin B1	increases expression	ISO	RGD:1321417	6480464	Aflatoxin B1 results in increased expression of MAP3K14 mRNA	CTD	PMID:19770486
Map3k14	Rat	aflatoxin B1	decreases methylation	ISO	RGD:1321416	6480464	Aflatoxin B1 results in decreased methylation of MAP3K14 gene	CTD	PMID:27153756
Map3k14	Rat	all-trans-retinoic acid	increases expression	ISO	RGD:1321416	6480464	Tretinoin results in increased expression of MAP3K14 mRNA	CTD	PMID:23724009
Map3k14	Rat	aristolochic acid A	increases expression	ISO	RGD:1321416	6480464	aristolochic acid I results in increased expression of MAP3K14 mRNA	CTD	PMID:33212167
Map3k14	Rat	arsane	multiple interactions	ISO	RGD:1321416	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Map3k14	Rat	arsenic atom	multiple interactions	ISO	RGD:1321416	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Map3k14	Rat	arsenite(3-)	multiple interactions	ISO	RGD:1321416	6480464	arsenite inhibits the reaction [MAP3K14 protein results in increased activity of CHUK protein]; arsenite inhibits more ...	CTD	PMID:10967126
Map3k14	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1321416	6480464	Benzo(a)pyrene results in increased expression of MAP3K14 mRNA	CTD	PMID:26238291
Map3k14	Rat	benzo[a]pyrene	affects methylation	ISO	RGD:1321416	6480464	Benzo(a)pyrene affects the methylation of MAP3K14 intron	CTD	PMID:30157460
Map3k14	Rat	benzo[a]pyrene	increases methylation	ISO	RGD:1321416	6480464	Benzo(a)pyrene results in increased methylation of MAP3K14 5' UTR	CTD	PMID:27901495
Map3k14	Rat	benzo[e]pyrene	increases methylation	ISO	RGD:1321416	6480464	benzo(e)pyrene results in increased methylation of MAP3K14 intron	CTD	PMID:30157460
Map3k14	Rat	bis(2-ethylhexyl) phthalate	increases expression	ISO	RGD:1321417	6480464	Diethylhexyl Phthalate results in increased expression of MAP3K14 mRNA	CTD	PMID:19850644
Map3k14	Rat	bis(2-ethylhexyl) phthalate	multiple interactions	ISO	RGD:1321417	6480464	PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of MAP3K14 mRNA]	CTD	PMID:19850644
Map3k14	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of MAP3K14 mRNA	CTD	PMID:25181051
Map3k14	Rat	bisphenol A	increases expression	ISO	RGD:1321417	6480464	bisphenol A results in increased expression of MAP3K14 mRNA	CTD	PMID:32156529
Map3k14	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of MAP3K14 mRNA	CTD	PMID:30816183\|PMID:32528016\|PMID:34947998
Map3k14	Rat	bisphenol A	multiple interactions	ISO	RGD:1321416	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...	CTD	PMID:28628672
Map3k14	Rat	bisphenol F	multiple interactions	ISO	RGD:1321416	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ...	CTD	PMID:28628672
Map3k14	Rat	butanal	increases expression	ISO	RGD:1321416	6480464	butyraldehyde results in increased expression of MAP3K14 mRNA	CTD	PMID:26079696
Map3k14	Rat	cadmium atom	increases expression	ISO	RGD:1321416	6480464	Cadmium results in increased expression of MAP3K14 mRNA	CTD	PMID:22562489
Map3k14	Rat	calcitriol	increases expression	ISO	RGD:1321416	6480464	Calcitriol results in increased expression of MAP3K14 mRNA	CTD	PMID:21592394
Map3k14	Rat	calcitriol	multiple interactions	ISO	RGD:1321416	6480464	[Testosterone co-treated with Calcitriol] results in increased expression of MAP3K14 mRNA	CTD	PMID:21592394
Map3k14	Rat	carbon nanotube	increases expression	ISO	RGD:1321417	6480464	Nanotubes, Carbon results in increased expression of MAP3K14 mRNA	CTD	PMID:25620056
Map3k14	Rat	CGP 52608	multiple interactions	ISO	RGD:1321416	6480464	CGP 52608 promotes the reaction [RORA protein binds to MAP3K14 gene]	CTD	PMID:28238834
Map3k14	Rat	ciguatoxin CTX1B	affects expression	ISO	RGD:1321417	6480464	Ciguatoxins affects the expression of MAP3K14 mRNA	CTD	PMID:18353800
Map3k14	Rat	cisplatin	decreases expression	ISO	RGD:1321416	6480464	Cisplatin results in decreased expression of MAP3K14 mRNA	CTD	PMID:27392435
Map3k14	Rat	cisplatin	multiple interactions	ISO	RGD:1321416	6480464	[Cisplatin co-treated with jinfukang] results in decreased expression of MAP3K14 mRNA	CTD	PMID:27392435
Map3k14	Rat	copper atom	multiple interactions	ISO	RGD:1321416	6480464	[Chelating Agents binds to Copper] which results in increased expression of MAP3K14 mRNA	CTD	PMID:30911355
Map3k14	Rat	copper(0)	multiple interactions	ISO	RGD:1321416	6480464	[Chelating Agents binds to Copper] which results in increased expression of MAP3K14 mRNA	CTD	PMID:30911355
Map3k14	Rat	copper(II) sulfate	increases expression	ISO	RGD:1321416	6480464	Copper Sulfate results in increased expression of MAP3K14 mRNA	CTD	PMID:19549813
Map3k14	Rat	Cuprizon	increases expression	EXP		6480464	Cuprizone results in increased expression of MAP3K14 mRNA	CTD	PMID:26577399
Map3k14	Rat	cyclosporin A	increases expression	ISO	RGD:1321416	6480464	Cyclosporine results in increased expression of MAP3K14 mRNA	CTD	PMID:20106945\|PMID:25562108
Map3k14	Rat	cylindrospermopsin	increases expression	ISO	RGD:1321416	6480464	cylindrospermopsin results in increased expression of MAP3K14 mRNA	CTD	PMID:24921660
Map3k14	Rat	dexamethasone	multiple interactions	ISO	RGD:1321416	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...	CTD	PMID:28628672
Map3k14	Rat	diallyl trisulfide	decreases expression	ISO	RGD:1321416	6480464	diallyl trisulfide results in decreased expression of MAP3K14 mRNA	CTD	PMID:34995734
Map3k14	Rat	dicrotophos	increases expression	ISO	RGD:1321416	6480464	dicrotophos results in increased expression of MAP3K14 mRNA	CTD	PMID:28302478
Map3k14	Rat	dieldrin	increases expression	ISO	RGD:1321416	6480464	Dieldrin results in increased expression of MAP3K14 mRNA	CTD	PMID:31068361
Map3k14	Rat	dimethylarsinic acid	increases expression	ISO	RGD:1321417	6480464	Cacodylic Acid results in increased expression of MAP3K14 mRNA	CTD	PMID:17441966
Map3k14	Rat	disodium selenite	decreases expression	ISO	RGD:1321416	6480464	Sodium Selenite results in decreased expression of MAP3K14 mRNA	CTD	PMID:16705456
Map3k14	Rat	dorsomorphin	multiple interactions	ISO	RGD:1321416	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Map3k14	Rat	Fusarenone X	increases expression	ISO	RGD:1321417	6480464	fusarenon-X results in increased expression of MAP3K14 mRNA	CTD	PMID:24983900
Map3k14	Rat	genistein	decreases expression	ISO	RGD:1321416	6480464	Genistein results in decreased expression of MAP3K14 mRNA	CTD	PMID:22228119
Map3k14	Rat	gentamycin	increases expression	EXP		6480464	Gentamicins results in increased expression of MAP3K14 mRNA	CTD	PMID:33387578
Map3k14	Rat	ibrutinib	decreases response to substance	ISO	RGD:1321416	6480464	MAP3K14 protein mutant form results in decreased susceptibility to ibrutinib	CTD	PMID:26254443
Map3k14	Rat	indometacin	multiple interactions	ISO	RGD:1321416	6480464	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...	CTD	PMID:28628672
Map3k14	Rat	iron atom	multiple interactions	EXP		6480464	MAP3K14 protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; MAP3K14 protein more ...	CTD	PMID:17172471
Map3k14	Rat	iron(0)	multiple interactions	EXP		6480464	MAP3K14 protein affects the reaction [Iron results in increased phosphorylation of NFKBIA protein]; MAP3K14 protein more ...	CTD	PMID:17172471
Map3k14	Rat	iron(2+) sulfate (anhydrous)	multiple interactions	EXP		6480464	MAP3K14 protein affects the reaction [ferrous sulfate results in increased phosphorylation of NFKBIA protein]; MAP3K14 more ...	CTD	PMID:17172471
Map3k14	Rat	leflunomide	increases expression	ISO	RGD:1321416	6480464	leflunomide results in increased expression of MAP3K14 mRNA	CTD	PMID:28988120
Map3k14	Rat	Licochalcone B	increases expression	ISO	RGD:1321416	6480464	licochalcone B results in increased expression of MAP3K14 mRNA	CTD	PMID:33647349
Map3k14	Rat	lipopolysaccharide	multiple interactions	EXP		6480464	MAP3K14 protein affects the reaction [Manganese promotes the reaction [Lipopolysaccharides results in increased phosphorylation of more ...	CTD	PMID:15010209
Map3k14	Rat	lipopolysaccharide	multiple interactions	ISO	RGD:1321416	6480464	[NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of MAP3K14 mRNA	CTD	PMID:35877022
Map3k14	Rat	manganese atom	multiple interactions	EXP		6480464	MAP3K14 protein affects the reaction [Manganese promotes the reaction [Lipopolysaccharides results in increased phosphorylation of more ...	CTD	PMID:15010209
Map3k14	Rat	manganese atom	multiple interactions	ISO	RGD:1321416	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Map3k14	Rat	manganese(0)	multiple interactions	EXP		6480464	MAP3K14 protein affects the reaction [Manganese promotes the reaction [Lipopolysaccharides results in increased phosphorylation of more ...	CTD	PMID:15010209
Map3k14	Rat	manganese(0)	multiple interactions	ISO	RGD:1321416	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Map3k14	Rat	manganese(II) chloride	multiple interactions	ISO	RGD:1321416	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Map3k14	Rat	mangiferin	decreases phosphorylation	ISO	RGD:1321416	6480464	mangiferin results in decreased phosphorylation of MAP3K14 protein	CTD	PMID:26996543
Map3k14	Rat	mercury dibromide	multiple interactions	ISO	RGD:1321416	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Map3k14	Rat	metacetamol	increases expression	ISO	RGD:1321417	6480464	3-hydroxyacetanilide results in increased expression of MAP3K14 mRNA	CTD	PMID:18544908
Map3k14	Rat	methapyrilene	increases methylation	ISO	RGD:1321416	6480464	Methapyrilene results in increased methylation of MAP3K14 intron	CTD	PMID:30157460
Map3k14	Rat	methotrexate	increases expression	ISO	RGD:1321416	6480464	Methotrexate results in increased expression of MAP3K14 mRNA	CTD	PMID:21678067
Map3k14	Rat	methylmercury chloride	increases expression	ISO	RGD:1321416	6480464	methylmercuric chloride results in increased expression of MAP3K14 mRNA	CTD	PMID:28001369
Map3k14	Rat	N-methyl-4-phenylpyridinium	affects expression	ISO	RGD:1321416	6480464	1-Methyl-4-phenylpyridinium affects the expression of MAP3K14 mRNA	CTD	PMID:12710931
Map3k14	Rat	nickel atom	increases expression	ISO	RGD:1321416	6480464	Nickel results in increased expression of MAP3K14 mRNA	CTD	PMID:25583101
Map3k14	Rat	nickel sulfate	increases expression	ISO	RGD:1321416	6480464	nickel sulfate results in increased expression of MAP3K14 mRNA	CTD	PMID:16780908
Map3k14	Rat	nitrates	multiple interactions	ISO	RGD:1321417	6480464	[Particulate Matter results in increased abundance of Nitrates] which results in increased expression of MAP3K14 more ...	CTD	PMID:35964746
Map3k14	Rat	o-anisidine	decreases expression	ISO	RGD:1321416	6480464	2-anisidine results in decreased expression of MAP3K14 mRNA	CTD	PMID:28089782
Map3k14	Rat	obeticholic acid	decreases expression	ISO	RGD:1321416	6480464	obeticholic acid results in decreased expression of MAP3K14 mRNA	CTD	PMID:27939613
Map3k14	Rat	ochratoxin A	decreases expression	ISO	RGD:1321416	6480464	ochratoxin A results in decreased expression of MAP3K14 mRNA	CTD	PMID:30763683
Map3k14	Rat	okadaic acid	increases expression	ISO	RGD:1321416	6480464	Okadaic Acid results in increased expression of MAP3K14 mRNA	CTD	PMID:38832940
Map3k14	Rat	p-chloromercuribenzoic acid	multiple interactions	ISO	RGD:1321416	6480464	[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Map3k14	Rat	p-menthan-3-ol	increases expression	ISO	RGD:1321416	6480464	Menthol results in increased expression of MAP3K14 mRNA	CTD	PMID:26760959
Map3k14	Rat	paracetamol	increases expression	ISO	RGD:1321417	6480464	Acetaminophen results in increased expression of MAP3K14 mRNA	CTD	PMID:18544908
Map3k14	Rat	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of MAP3K14 mRNA	CTD	PMID:33387578
Map3k14	Rat	paracetamol	increases expression	ISO	RGD:1321416	6480464	Acetaminophen results in increased expression of MAP3K14 mRNA	CTD	PMID:21420995
Map3k14	Rat	pentachlorophenol	increases expression	ISO	RGD:1321417	6480464	Pentachlorophenol results in increased expression of MAP3K14 mRNA	CTD	PMID:23892564
Map3k14	Rat	perfluorohexanesulfonic acid	decreases expression	ISO	RGD:1321416	6480464	perfluorohexanesulfonic acid results in decreased expression of MAP3K14 mRNA	CTD	PMID:25812627
Map3k14	Rat	perfluorohexanesulfonic acid	increases expression	ISO	RGD:1321417	6480464	perfluorohexanesulfonic acid results in increased expression of MAP3K14 mRNA	CTD	PMID:37995155
Map3k14	Rat	perfluorooctane-1-sulfonic acid	decreases expression	ISO	RGD:1321416	6480464	perfluorooctane sulfonic acid results in decreased expression of MAP3K14 mRNA	CTD	PMID:25812627
Map3k14	Rat	perfluorooctanoic acid	decreases expression	ISO	RGD:1321416	6480464	perfluorooctanoic acid results in decreased expression of MAP3K14 mRNA	CTD	PMID:25812627
Map3k14	Rat	phenobarbital	affects expression	ISO	RGD:1321417	6480464	Phenobarbital affects the expression of MAP3K14 mRNA	CTD	PMID:19136022
Map3k14	Rat	phenylmercury acetate	increases expression	ISO	RGD:1321416	6480464	Phenylmercuric Acetate results in increased expression of MAP3K14 mRNA	CTD	PMID:26272509
Map3k14	Rat	phenylmercury acetate	multiple interactions	ISO	RGD:1321416	6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Map3k14	Rat	phorbol 13-acetate 12-myristate	increases expression	ISO	RGD:1321416	6480464	Tetradecanoylphorbol Acetate results in increased expression of MAP3K14 mRNA	CTD	PMID:10910055
Map3k14	Rat	pirinixic acid	multiple interactions	ISO	RGD:1321416	6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ...	CTD	PMID:19710929
Map3k14	Rat	pirinixic acid	decreases expression	ISO	RGD:1321417	6480464	pirinixic acid results in decreased expression of MAP3K14 mRNA	CTD	PMID:20813756
Map3k14	Rat	pirinixic acid	affects expression	ISO	RGD:1321417	6480464	pirinixic acid affects the expression of MAP3K14 mRNA	CTD	PMID:19136022
Map3k14	Rat	potassium chromate	increases expression	ISO	RGD:1321416	6480464	potassium chromate(VI) results in increased expression of MAP3K14 mRNA	CTD	PMID:22714537
Map3k14	Rat	quercetin	increases expression	ISO	RGD:1321416	6480464	Quercetin results in increased expression of MAP3K14 mRNA	CTD	PMID:21632981
Map3k14	Rat	resveratrol	decreases expression	ISO	RGD:1321416	6480464	resveratrol results in decreased expression of MAP3K14 mRNA	CTD	PMID:25888808
Map3k14	Rat	SB 431542	multiple interactions	ISO	RGD:1321416	6480464	[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
Map3k14	Rat	silicon dioxide	increases expression	ISO	RGD:1321416	6480464	Silicon Dioxide analog results in increased expression of MAP3K14 mRNA	CTD	PMID:25895662
Map3k14	Rat	silicon dioxide	increases expression	ISO	RGD:1321417	6480464	Silicon Dioxide results in increased expression of MAP3K14 mRNA	CTD	PMID:23221170
Map3k14	Rat	silver atom	increases expression	ISO	RGD:1321416	6480464	Silver results in increased expression of MAP3K14 mRNA	CTD	PMID:26014281\|PMID:28959546
Map3k14	Rat	silver(0)	increases expression	ISO	RGD:1321416	6480464	Silver results in increased expression of MAP3K14 mRNA	CTD	PMID:26014281\|PMID:28959546
Map3k14	Rat	simvastatin	decreases expression	ISO	RGD:1321416	6480464	Simvastatin results in decreased expression of MAP3K14 mRNA	CTD	PMID:17277159
Map3k14	Rat	SM-164	increases expression	ISO	RGD:1321416	6480464	SM 164 results in increased expression of MAP3K14 protein	CTD	PMID:22241084
Map3k14	Rat	sodium arsenite	increases expression	ISO	RGD:1321416	6480464	sodium arsenite results in increased expression of MAP3K14 mRNA	CTD	PMID:10910055\|PMID:38568856
Map3k14	Rat	sodium arsenite	multiple interactions	ISO	RGD:1321416	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Map3k14	Rat	sulfates	multiple interactions	ISO	RGD:1321416	6480464	[Soot co-treated with Sulfates] affects the methylation of MAP3K14 promoter	CTD	PMID:25395096
Map3k14	Rat	testosterone	multiple interactions	ISO	RGD:1321416	6480464	[Testosterone co-treated with Calcitriol] results in increased expression of MAP3K14 mRNA	CTD	PMID:21592394
Map3k14	Rat	testosterone	increases expression	ISO	RGD:1321416	6480464	Testosterone results in increased expression of MAP3K14 mRNA	CTD	PMID:21592394
Map3k14	Rat	tetrachloromethane	affects expression	ISO	RGD:1321417	6480464	Carbon Tetrachloride affects the expression of MAP3K14 mRNA	CTD	PMID:17484886
Map3k14	Rat	tetraphene	increases expression	ISO	RGD:1321417	6480464	benz(a)anthracene results in increased expression of MAP3K14 mRNA	CTD	PMID:26377693
Map3k14	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of MAP3K14 mRNA	CTD	PMID:34492290
Map3k14	Rat	thiram	increases expression	ISO	RGD:1321416	6480464	Thiram results in increased expression of MAP3K14 mRNA	CTD	PMID:38568856
Map3k14	Rat	titanium dioxide	decreases methylation	ISO	RGD:1321417	6480464	titanium dioxide results in decreased methylation of MAP3K14 gene; titanium dioxide results in decreased methylation more ...	CTD	PMID:35295148
Map3k14	Rat	trichloroethene	decreases expression	EXP		6480464	Trichloroethylene results in decreased expression of MAP3K14 mRNA	CTD	PMID:33387578
Map3k14	Rat	Tylophorine	increases expression	ISO	RGD:1321416	6480464	tylophorine analog results in increased expression of MAP3K14 mRNA	CTD	PMID:19284764
Map3k14	Rat	urethane	increases expression	ISO	RGD:1321416	6480464	Urethane results in increased expression of MAP3K14 mRNA	CTD	PMID:28818685
Map3k14	Rat	valproic acid	affects expression	ISO	RGD:1321416	6480464	Valproic Acid affects the expression of MAP3K14 mRNA	CTD	PMID:25979313
Map3k14	Rat	valproic acid	increases expression	ISO	RGD:1321416	6480464	Valproic Acid results in increased expression of MAP3K14 mRNA	CTD	PMID:28001369\|PMID:29154799
Map3k14	Rat	vanadium atom	decreases expression	ISO	RGD:1321416	6480464	Vanadium results in decreased expression of MAP3K14 mRNA	CTD	PMID:19000753
Map3k14	Rat	vanadium(0)	decreases expression	ISO	RGD:1321416	6480464	Vanadium results in decreased expression of MAP3K14 mRNA	CTD	PMID:19000753
Map3k14	Rat	zerumbone	multiple interactions	ISO	RGD:1321416	6480464	zerumbone inhibits the reaction [MAP3K14 protein results in increased activity of [NFKB1 protein binds to more ...	CTD	PMID:16007145
Map3k14	Rat	zinc atom	multiple interactions	ISO	RGD:1321416	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of MAP3K14 mRNA	CTD	PMID:18593933
Map3k14	Rat	zinc(0)	multiple interactions	ISO	RGD:1321416	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of MAP3K14 mRNA	CTD	PMID:18593933

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	cellular response to mechanical stimulus	involved_in	ISO	RGD:1321416	1624291	PMID:19593445	RGD	PMID:19593445
Map3k14	Rat	cellular response to mechanical stimulus	involved_in	IEA	UniProtKB:Q99558\|ensembl:ENSP00000478552	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	defense response to virus	involved_in	IEA	UniProtKB:Q99558\|ensembl:ENSP00000478552	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	immune response	involved_in	ISO	RGD:1321417	1624291	PMID:11239468	RGD	PMID:11239468
Map3k14	Rat	immune response	involved_in	IEA	UniProtKB:Q9WUL6\|ensembl:ENSMUSP00000021324	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	intracellular signal transduction	involved_in	IEA	ARBA:ARBA00026887	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Map3k14	Rat	MAPK cascade	involved_in	IBA	FB:FBgn0024329\|PANTHER:PTN002519713\|PomBase:SPAC1006.09\|PomBase:SPAC9G1.02\|SGD:S000000669\|SGD:S000003631\|SGD:S000005314\|TAIR:locus:2133559\|UniProtKB:P41279\|UniProtKB:Q9Y6R4	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Map3k14	Rat	non-canonical NF-kappaB signal transduction	involved_in	ISO	RGD:1321417	1624291	PMID:11239468	RGD	PMID:11239468
Map3k14	Rat	non-canonical NF-kappaB signal transduction	involved_in	IEA	UniProtKB:Q99558\|ensembl:ENSP00000478552	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	non-canonical NF-kappaB signal transduction	involved_in	IEA	UniProtKB:Q9WUL6\|ensembl:ENSMUSP00000021324	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	non-canonical NF-kappaB signal transduction	involved_in	ISO	RGD:1321416	1624291	PMID:10094049	RGD	PMID:10094049
Map3k14	Rat	protein phosphorylation		IMP		2313425		RGD

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	cytoplasm	located_in	IEA	UniRule:UR001376753	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Map3k14	Rat	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Map3k14	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Map3k14	Rat	cytosol	located_in	IEA	UniProtKB:Q99558\|ensembl:ENSP00000478552	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	cytosol	located_in	ISO	RGD:1321416	1624291		RGD	GO_REF:0000052
Map3k14	Rat	fibrillar center	located_in	IEA	UniProtKB:Q99558\|ensembl:ENSP00000478552	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	fibrillar center	located_in	ISO	RGD:1321416	1624291		RGD	GO_REF:0000052
Map3k14	Rat	nucleoplasm	located_in	IEA	UniProtKB:Q99558\|ensembl:ENSP00000478552	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	nucleoplasm	located_in	ISO	RGD:1321416	1624291		RGD	GO_REF:0000052

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	ATP binding	enables	IEA	UniRule:UR001376753\|UniRule:UR001503341	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Map3k14	Rat	ATP binding	enables	IEA	UniProtKB-KW:KW-0067	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Map3k14	Rat	ATP binding	enables	IEA	InterPro:IPR000719\|InterPro:IPR017441	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Map3k14	Rat	kinase activity	enables	IEA	UniProtKB-KW:KW-0418	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Map3k14	Rat	MAP kinase kinase kinase activity	enables	IEA	EC:2.7.11.25	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Map3k14	Rat	nucleotide binding	enables	IEA	UniProtKB-KW:KW-0547	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Map3k14	Rat	nucleotide binding	enables	IEA	UniRule:UR001503341	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Map3k14	Rat	protein binding	enables	ISO	RGD:1321417	1624291	UniProtKB:P48453\|UniProtKB:P63328\|UniProtKB:Q00653 PMID:11239468, PMID:26029823	RGD	PMID:11239468\|PMID:26029823
Map3k14	Rat	protein binding	enables	ISO	RGD:1321416	1624291	UniProtKB:O14920\|UniProtKB:O15111\|UniProtKB:P01112\|UniProtKB:P07900\|UniProtKB:P08238\|UniProtKB:P36578\|UniProtKB:P59046\|UniProtKB:P62258\|UniProtKB:P62277\|UniProtKB:P62280\|UniProtKB:P62917\|UniProtKB:Q02878\|UniProtKB:Q12933\|UniProtKB:Q13114\|UniProtKB:Q14790\|UniProtKB:Q14974\|UniProtKB:Q16543\|UniProtKB:Q60680-2\|UniProtKB:Q60803\|UniProtKB:Q9Y6K9 PMID:10733566, PMID:12884866, PMID:14743216, PMID:16286467, PMID:16498412, PMID:17158868, PMID:17237370, PMID:22939624, PMID:25036637, PMID:25241761, PMID:25416956, PMID:28514442, PMID:30833792, more ...	RGD	PMID:10733566\|PMID:12884866\|PMID:14743216\|PMID:16286467\|PMID:16498412\|PMID:17158868\|PMID:17237370\|PMID:22939624\|PMID:25036637\|PMID:25241761\|PMID:25416956\|PMID:28514442\|PMID:30833792\|PMID:31980649\|PMID:32296183\|PMID:32707033\|PMID:32814053\|PMID:33961781\|PMID:36931259\|PMID:9020361\|PMID:9520446
Map3k14	Rat	protein kinase activity		IMP		2313425		RGD
Map3k14	Rat	protein kinase activity	enables	IEA	UniRule:UR001376753	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Map3k14	Rat	protein kinase activity	enables	IEA	UniProtKB:Q99558\|ensembl:ENSP00000478552	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	protein kinase activity	enables	IEA	ARBA:ARBA00027018	1600115	GO_REF:0000117	UniProt	GO_REF:0000117
Map3k14	Rat	protein kinase activity	enables	IEA	InterPro:IPR000719\|InterPro:IPR008271\|InterPro:IPR017425	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Map3k14	Rat	protein kinase activity	enables	ISO	RGD:1321416	1624291	PMID:15001576	RGD	PMID:15001576
Map3k14	Rat	protein serine/threonine kinase activity	enables	ISO	RGD:1321416	1624291	PMID:9520446	RGD	PMID:9520446
Map3k14	Rat	protein serine/threonine kinase activity	enables	IEA	UniRule:UR001376753	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Map3k14	Rat	protein serine/threonine kinase activity	enables	ISO	RGD:1321417	1624291	PMID:11239468	RGD	PMID:11239468
Map3k14	Rat	protein serine/threonine kinase activity	enables	IEA	UniProtKB:Q9WUL6\|ensembl:ENSMUSP00000021324	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Map3k14	Rat	protein serine/threonine kinase activity	enables	IEA	InterPro:IPR042787	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Map3k14	Rat	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

Molecular Pathway Annotations Click to see Annotation Detail View

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	nuclear factor kappa B signaling pathway		ISO	RGD:1321416	2292172		RGD

Imported Annotations - KEGG (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	apoptotic cell death pathway		IEA		6907045		KEGG	rno:04210
Map3k14	Rat	mitogen activated protein kinase signaling pathway		IEA		6907045		KEGG	rno:04010
Map3k14	Rat	T cell receptor signaling pathway		IEA		6907045		KEGG	rno:04660

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Map3k14	Rat	nuclear factor kappa B signaling pathway		ISO	RGD:1321416	6484113		PID	PID:200048

Disease Annotations Click to see Annotation Detail View

hereditary breast ovarian cancer syndrome (ISO)

immunodeficiency 112 (ISO)

primary biliary cholangitis (ISS)

Sjogren's syndrome (ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1'-acetoxychavicol acetate (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid (ISO)

2-hydroxyethyl methacrylate (ISO)

2-palmitoylglycerol (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-phenylprop-2-enal (EXP)

4,4'-sulfonyldiphenol (ISO)

4-nitrophenol (ISO)

acrolein (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium atom (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

dexamethasone (ISO)

diallyl trisulfide (ISO)

dicrotophos (ISO)

dieldrin (ISO)

dimethylarsinic acid (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

Fusarenone X (ISO)

genistein (ISO)

gentamycin (EXP)

ibrutinib (ISO)

indometacin (ISO)

iron atom (EXP)

iron(0) (EXP)

iron(2+) sulfate (anhydrous) (EXP)

leflunomide (ISO)

Licochalcone B (ISO)

lipopolysaccharide (EXP,ISO)

manganese atom (EXP,ISO)

manganese(0) (EXP,ISO)

manganese(II) chloride (ISO)

mangiferin (ISO)

mercury dibromide (ISO)

metacetamol (ISO)

methapyrilene (ISO)

methotrexate (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

nitrates (ISO)

o-anisidine (ISO)

obeticholic acid (ISO)

ochratoxin A (ISO)

okadaic acid (ISO)

p-chloromercuribenzoic acid (ISO)

p-menthan-3-ol (ISO)

paracetamol (EXP,ISO)

pentachlorophenol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

phorbol 13-acetate 12-myristate (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

quercetin (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

simvastatin (ISO)

SM-164 (ISO)

sodium arsenite (ISO)

sulfates (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

tetraphene (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

Tylophorine (ISO)

urethane (ISO)

valproic acid (ISO)

vanadium atom (ISO)

vanadium(0) (ISO)

zerumbone (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to mechanical stimulus (IEA,ISO)

defense response to virus (IEA)

immune response (IEA,ISO)

intracellular signal transduction (IEA)

MAPK cascade (IBA)

non-canonical NF-kappaB signal transduction (IEA,ISO)

protein phosphorylation (IMP)

Cellular Component

cytoplasm (IEA)

cytosol (IEA,ISO)

fibrillar center (IEA,ISO)

nucleoplasm (IEA,ISO)

Molecular Function

ATP binding (IEA)

kinase activity (IEA)

MAP kinase kinase kinase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

protein kinase activity (IEA,IMP,ISO)

protein serine/threonine kinase activity (IEA,ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

apoptotic cell death pathway (IEA)

mitogen activated protein kinase signaling pathway (IEA)

nuclear factor kappa B signaling pathway (ISO)

T cell receptor signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Shared principles in NF-kappaB signaling.	Hayden MS and Ghosh S, Cell. 2008 Feb 8;132(3):344-62.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Protective effect of Ginkgolids (A+B) is associated with inhibition of NIK/IKK/IkappaB/NF-kappaB signaling pathway in a rat model of permanent focal cerebral ischemia.	Wang X, etal., Brain Res. 2008 Oct 9;1234:8-15. Epub 2008 Aug 5.

Additional References at PubMed

PMID:9520446	PMID:10094049	PMID:11239468	PMID:15001576	PMID:18056702	PMID:18305221	PMID:19593445	PMID:21478870	PMID:22871113

Genomics

Comparative Map Data

Map3k14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	88,665,417 - 88,715,669 (-)	NCBI		GRCr8
mRatBN7.2	10	88,165,349 - 88,215,558 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	88,165,351 - 88,215,523 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	93,201,107 - 93,251,268 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	92,668,001 - 92,718,220 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	88,061,351 - 88,111,570 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	91,303,428 - 91,353,601 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	91,303,428 - 91,353,601 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	91,074,396 - 91,121,436 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	92,406,098 - 92,456,276 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	92,421,198 - 92,444,501 (-)	NCBI
Celera	10	86,866,471 - 86,916,375 (-)	NCBI		Celera
Cytogenetic Map	10	q32.1	NCBI

MAP3K14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	45,263,119 - 45,317,020 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	45,263,119 - 45,317,029 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	43,340,486 - 43,394,386 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	40,696,271 - 40,750,197 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	40,696,277 - 40,724,123	NCBI
Celera	17	40,049,855 - 40,103,781 (-)	NCBI		Celera
Cytogenetic Map	17	q21.31	NCBI
HuRef	17	39,101,255 - 39,155,179 (-)	NCBI		HuRef
CHM1_1	17	43,575,752 - 43,629,721 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	46,116,902 - 46,170,784 (-)	NCBI		T2T-CHM13v2.0

Map3k14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	103,110,590 - 103,158,227 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	103,110,588 - 103,158,298 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	103,219,764 - 103,267,401 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	103,219,762 - 103,267,472 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	103,081,078 - 103,128,715 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	103,035,854 - 103,083,491 (-)	NCBI		MGSCv36	mm8
Celera	11	114,933,508 - 114,981,179 (-)	NCBI		Celera
Cytogenetic Map	11	E1	NCBI
cM Map	11	66.8	NCBI

Map3k14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	17,908,827 - 17,926,151 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	17,907,800 - 17,954,821 (-)	NCBI	ChiLan1.0	ChiLan1.0

MAP3K14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	19,521,228 - 19,575,128 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	21,489,935 - 21,543,815 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	12,011,037 - 12,064,978 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	12,183,243 - 12,237,131 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	12,183,243 - 12,237,131 (+)	Ensembl	panpan1.1		panPan2

MAP3K14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	18,255,416 - 18,302,405 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	18,280,198 - 18,302,401 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	17,640,218 - 17,687,188 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	18,928,453 - 18,975,466 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	18,928,497 - 18,975,502 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	17,806,803 - 17,853,778 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	17,985,479 - 18,032,427 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	18,141,265 - 18,188,242 (+)	NCBI		UU_Cfam_GSD_1.0

Map3k14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	17,602,812 - 17,645,706 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936541	1,548,875 - 1,591,833 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936541	1,548,892 - 1,591,770 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAP3K14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	18,142,952 - 18,182,928 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	18,142,899 - 18,182,931 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	18,391,601 - 18,431,641 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAP3K14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	61,100,298 - 61,153,984 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	61,100,352 - 61,155,052 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	31,837,235 - 31,890,835 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Map3k14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	167,990 - 203,784 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624795	167,959 - 207,421 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Map3k14
376 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	534
Count of miRNA genes:	254
Interacting mature miRNAs:	300
Transcripts:	ENSRNOT00000004532
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	50574707	95574707	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63221094	107211142	Rat
631555	Bp134	Blood pressure QTL 134		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	80515287	91230079	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
1549831	Bss6	Bone structure and strength QTL 6	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	10	57576521	102576521	Rat
70164	Bw21	Body weight QTL 21	4.36	0.00005	body mass (VT:0001259)	body weight (CMO:0000012)	10	53797494	98952626	Rat
4889948	Bss91	Bone structure and strength QTL 91	4		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	10	82564856	92369470	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	72224939	107211142	Rat
1579919	Bp281	Blood pressure QTL 281		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	74372084	94965338	Rat
1302404	Cia27	Collagen induced arthritis QTL 27	2.6	0.0045	joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	10	76452683	107211142	Rat
1300107	Rf18	Renal function QTL 18	3.41		urine output (VT:0003620)	timed urine volume (CMO:0000260)	10	78775516	98279596	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44441699	89441699	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45029650	95600334	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	82685200	107211142	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
10450495	Bp383	Blood pressure QTL 383		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	94965338	Rat
2313856	Bp342	Blood pressure QTL 342	4.4	0.0001	life span trait (VT:0005372)	age at time of death (CMO:0001193)	10	87307617	96121100	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2292617	Ept18	Estrogen-induced pituitary tumorigenesis QTL 18	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73453136	96120911	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62057807	107057807	Rat
2293646	Bss25	Bone structure and strength QTL 25	10.96	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	10	69738412	107211142	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
2300172	Bmd57	Bone mineral density QTL 57	9.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	10	69738412	107211142	Rat
70193	Mcs7	Mammary carcinoma susceptibility QTL 7	2.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72224939	107211142	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62057807	107057807	Rat
61363	Oia3	Oil induced arthritis QTL 3		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87307617	107211142	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44441699	89441699	Rat
1357344	Bp249	Blood pressure QTL 249		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	66743655	98003205	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
2306970	Anxrr22	Anxiety related response QTL 22	5.95		fear/anxiety-related behavior trait (VT:1000241)	number of periods of voluntary immobility (CMO:0001045)	10	61345276	98211570	Rat
1359017	Hrtrt21	Heart rate QTL 21	2.4		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	10	51772940	96772940	Rat
2293663	Bss33	Bone structure and strength QTL 33	9.34	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	10	69738412	107211142	Rat
7387312	Bw125	Body weight QTL 125	3	0.0047	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight (CMO:0000356)	10	64890616	107211142	Rat
2312672	Insul15	Insulin level QTL 15		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	10	57134272	102134272	Rat
6893357	Bw102	Body weight QTL 102	0.5	0.36	body mass (VT:0001259)	body weight (CMO:0000012)	10	80515287	101325465	Rat
2317029	Aia19	Adjuvant induced arthritis QTL 19	2.98		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	66978955	107211142	Rat
2303589	Bw87	Body weight QTL 87	2		body mass (VT:0001259)	body weight (CMO:0000012)	10	81285008	107211142	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
2306793	Ean5	Experimental allergic neuritis QTL 5	4.7		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	10	72552416	93995749	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
2306792	Ean4	Experimental allergic neuritis QTL 4	4		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	10	84022321	93995963	Rat
2317039	Aia6	Adjuvant induced arthritis QTL 6	4.31		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	66978955	107211142	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68420376	107211142	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
70364	Bp72	Blood pressure QTL 72			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	51121100	96121100	Rat
10450498	Bp384	Blood pressure QTL 384		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	67750049	107211142	Rat
4889492	Pancm2	Pancreatic morphology QTL 2	3.2		pancreatic beta cell morphology trait (VT:0005217)	ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)	10	76748906	107211142	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70199100	107211142	Rat
2293698	Bss43	Bone structure and strength QTL 43	5.33	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	10	59209888	104209888	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	51774612	95600334	Rat
1354608	Cm33	Cardiac mass QTL 33	2.8		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	10	54809292	99809292	Rat
1558643	Cm44	Cardiac mass QTL 44	4.8	0.0000368	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	61345276	99703528	Rat
631535	Cm51	Cardiac mass QTL 51	3		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	51786282	91669536	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40035094	102359817	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44441699	89441699	Rat
6893336	Cm75	Cardiac mass QTL 75	0.1	0.87	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	61345276	99703528	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47369470	92369470	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
12880055	Am11	Aortic mass QTL 11		0.004	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	84007272	95933025	Rat
2292438	Bp311	Blood pressure QTL 311			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	76246085	107211142	Rat
2312662	Slep8	Serum leptin concentration QTL 8		0.05	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	10	57134272	102134272	Rat
2301398	Kidm38	Kidney mass QTL 38		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	84007272	95933025	Rat
1600367	Mcs15	Mammary carcinoma susceptibility QTL 15	4.5		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	85565469	103884409	Rat
1358188	Ept9	Estrogen-induced pituitary tumorigenesis QTL 9	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73453136	96120911	Rat
631538	Oia5	Oil induced arthritis QTL 5			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	87055121	107211142	Rat
1642980	Bp300	Blood pressure QTL 300			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68383129	107211142	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat
2312668	Scl65	Serum cholesterol level QTL 65		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	57134272	102134272	Rat

Markers in Region

D10Rat142

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	88,207,600 - 88,207,815 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	91,345,679 - 91,345,893	NCBI	Rnor6.0
Rnor_5.0	10	91,113,514 - 91,113,728	UniSTS	Rnor5.0
RGSC_v3.4	10	92,448,354 - 92,448,568	UniSTS	RGSC3.4
RGSC_v3.4	10	92,448,353 - 92,448,568	RGD	RGSC3.4
RGSC_v3.1	10	92,462,723 - 92,462,938	RGD
Celera	10	86,908,452 - 86,908,666	UniSTS
RH 3.4 Map	10	899.0	RGD
RH 3.4 Map	10	899.0	UniSTS
SHRSP x BN Map	10	66.5	RGD
SHRSP x BN Map	10	66.5	UniSTS
Cytogenetic Map	10	q32.1	UniSTS

RH144612

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	88,165,436 - 88,165,586 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	91,303,514 - 91,303,663	NCBI	Rnor6.0
Rnor_5.0	10	91,074,482 - 91,074,631	UniSTS	Rnor5.0
RGSC_v3.4	10	92,406,184 - 92,406,333	UniSTS	RGSC3.4
Celera	10	86,866,557 - 86,866,706	UniSTS
RH 3.4 Map	10	897.6	UniSTS
Cytogenetic Map	10	q32.1	UniSTS

RH141437

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	88,202,662 - 88,202,861 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	91,340,741 - 91,340,939	NCBI	Rnor6.0
Rnor_6.0	10	90,862,005 - 90,862,203	NCBI	Rnor6.0
Rnor_5.0	10	90,637,644 - 90,637,842	UniSTS	Rnor5.0
Rnor_5.0	10	91,108,576 - 91,108,774	UniSTS	Rnor5.0
RGSC_v3.4	10	92,443,418 - 92,443,616	UniSTS	RGSC3.4
RH 3.4 Map	10	899.0	UniSTS
Cytogenetic Map	10	q32.1	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086417	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC136172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004532 ⟹ ENSRNOP00000004532

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	88,165,351 - 88,215,523 (-)	Ensembl
Rnor_6.0 Ensembl	10	91,303,428 - 91,353,601 (-)	Ensembl

RefSeq Acc Id:

NM_001108301 ⟹ NP_001101771

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	88,665,417 - 88,715,592 (-)	NCBI
mRatBN7.2	10	88,165,351 - 88,215,523 (-)	NCBI
Rnor_6.0	10	91,303,428 - 91,353,601 (-)	NCBI
Rnor_5.0	10	91,074,396 - 91,121,436 (-)	NCBI
RGSC_v3.4	10	92,406,098 - 92,456,276 (-)	RGD
Celera	10	86,866,471 - 86,916,375 (-)	RGD

Sequence:

show sequence

GCCCCGAGCGATCGCTGGCCAGCGAAGCGCCACACTCGCTTGTTTGAGGAGAACGGCGCTCCGC
CGGTGAGCACAAGCCTAGGAGATGGCCGTGATGGAAGTGGCCTGCCCAGGCACTCCTGGGTCGG
CAGTCGGGCAGCAGAAGGAGTTCGCCAAAGCCAAGGAGAAGACACAGTCACCAGGGAAGAAGCA
GAGCTGCATCTTCCAGCTCGAGGCGGTGGAGAAGAGCCCTGTGTTCTGTGGGAAGTGGGAGATC
CTCAACGATGTGATCACCAAAGGCACAGCCAAGGAAGGTTCCGAGGGCGGGCCCCCCGCCATCT
CCATCATCGCCCAGGCTGAATGTGAGAATAGCCAAGAGTTCAGCCCCACCTTCTCAGAGCGCAT
TTTCATCGCGGGGTCACAGCAGTACAGCCAGTCTGAGAGTCTTGATCAAATCCCCAACAATGTG
GCCCATGCAACTGAAGGCAAAATGGCCCGAGTGTGCCGGAAGGGGAAGCGTCACAGCAAAGCCC
GAAAAAAACGTAGGAAGAGGAGGTCGAAGTCACTGGCCCAGGCAGGAGTGGCCTTGGCCAAGCC
CCTGCCCAGAACCCCTGAGCAAGAGAGCTGTACCATCCCAGTGCAGGAAGATGAGTCTCCACTA
GGCAACCTCTATGCCAGAAATGTCTCCCAGTTCACCAAGCCTCTGAAGGGACCAGGCCTTGGCC
ACCTGTGCTTTAAGAAACAAGATGAAGGCCTGCGACCAGTGCTGCCTCGACCAGAACTCCACAA
ACTGATCAGCCCCCTGCAATGTCTAAACCACGTGTGGAAACTCCACCACCCGCAGGCCACAGGC
CCCCTGCCCCACCCCACTCACCCGTTCCCCTTCAGCAGAATGCCCCATCCTTTCCCATTCTACC
CCCTGGAGCCCTGGAGACCCTATACACTGAACCCGGCCTTCCTGGACAAACTAGCCGCTGTAAG
TGGCCAGCGGCCTCTGCCTGGCCCACCACACCTAAGCAAACCGGCCTACAGAGACAGTCAGAAG
CCCCTGCCTGGCCCACATCTGGAGTCCAGCTGCCTGTCCCGAGAGGCCCTAGAAAAGGTCCCTG
CCGAGGAATACCTGGTGCACGCGCTACAAGGAAGTGTGAGCTCAGGCCAGGCCCACAGCCTGGC
TAGCCTGGCTAAGACATGGTCATCAGGGAGCTCCAAGCTGCAGAGGTTCAGCCCTGAAACTGAG
GACAACGAGGGGGTCCTGCTTACTGAGAAACTCAAACCAGTGGATTATGAGTACCGGGAAGAGG
TCCACTGGATGACACACCAGCCTCGGGTGGGCAGAGGGTCCTTCGGCGAAGTCCACAGAATGAA
GGACAAGCAGACAGGCTTCCAGTGTGCTGTCAAAAAGGTACGGCTTGAGGTATTTCGGGCAGAG
GAACTGATAGCCTGTGCCGGACTGAGCTCGCCCAGGATCGTCCCTCTCTACGGAGCTGTAAGAG
AAGGCCCGTGGGTGAACATCTTCATGGAGCTGCTAGAAGGTGGCTCTCTAGGCCAGCTCATAAA
GCAGAAGGGCTGTCTGCCAGAAGACCGAGCCCTTTACTACCTGGGCCAGGCCCTGGAGGGGCTG
GAATACCTCCATACACACAGGGTTCTGCATGGCGACGTCAAAGCTGACAACGTGCTCCTGTCCA
GTGATGGAAGCCGAGCTGCCCTCTGTGACTTCGGCCATGCCTTGTGCCTACAACCTGATGGCCT
AGGAAAATCCTTGCTCACAGGGGACTACATTCCTGGCACAGAGACCCACATGGCCCCAGAAGTG
GTGCTGGGGAAGCCCTGTGATGCCAAGGTCGACATCTGGAGCAGCTGTTGCATGATGCTCCACA
TGCTCAATGGCTGCCACCCCTGGACTCAGTACTTCCGAGGCCCGCTCTGTCTCAAGATTGCCAG
CGAGCCTCCACCTGTCAGGGAGATTCCACCTTCCTGCACACCCCTCACAGCCCAGGCCATCCAA
GAGGGGCTGAGGAAAGAGCCCATCCACCGAGCATCTGCCATGGAACTTCGGAGGAAAGTGGGCA
AGGCGTTACAGGAAGTGGGAGGTCTGAAAAGCCCTTGGAAAGGAGAATATAAAGAGCCAAGACC
TCCACCCCAAGACCAAGCCCCCTGCCCCCAGACCTTACATACCCTGCCAAGAGAGAACCCACCA
GCCAAGGCCAACACAGACGGGGCCCCTGAGCGTCAGCCTCCTCTGCCGCCTGAACCACCGGAAC
CGAACAAAGCACCAGCCCTGAACCTGAGCAAGGAGGAGTCTGGCACCTGGGAACCCCTGCCTCT
GTCCTCCCTGGACCCAGCCCCTGCCAAAGGCCCCAGCTTGCCAGACCGGAGGGCAACCTTCCCG
GAGCTGGAGCTACAACAGCTGGAGATAGAACTGTTCCTAAACAGCCTGTCCCAGCCGTTTTCTC
TGGAGGAACAGGAACAGATTCTCTCCTGCCTCAGCATCGACAGCCTCTCACTGTCAGAGGACAG
TGAAAAGAACCCATCTAAGGCCTCTCAGAGCTCACGTGATACCCTGAGTTCCGGCGTGCACTCT
TGGAGCAGCCAAGCAGAGGCCAGAAGCTCCAGCTGCAGCATGGCGCTGGCCCGGGGACGGCCCA
CTGACATCCCGAGCTACTTCAACGGTGTCAAGGTCCAGATACAGTCTCTCAATGGCGAGCACCT
GCACATCCGGGAATTCCACCGGGTCAAGGTGGGAGACATTGCAACCGGCATCAGCAGCCAGATC
CCGGCCACAGCTTTCAGCTTGGTGACCAAAGATGGACAGCCTGTTTGCTATGACATGGAGGTGC
CAGACTCAGGCATCGACCTGCAGTGCACCCTAGCCCCTGATGGCAGCTTCGCTTGGGCCTGGAG
GGTCAAGCACGGCCAGCTGGAGAACCGGCCCTAGCCCTGTCTTCCAGCACCAGCTCTACTCTGG
CCACAGCAGGCTTCCTTTGAATCTCAGTACTCAGTGGCGCTCTGAGATGCTGGATGAGTCTGCT
CAGGCCCCTGCCAGTCCCCGGCTGGGCATAAGACCGGGGCTGTCGAGCAGCAAGCGGAGGAGCA
GAGTAAAACGCCTCCCAGGACTTGCCTGCCTCCTGCTGCTGGCTCCTGGCAGGAGAAACTCTTC
CCTCATGAGAAGACAAGGAGGAAGACAGGGGTCTCATCCCCCAGAGAGAGAGCCAGCGCTTTCT
GTGATGCTCCAAATGAGGTAGCCAGACCCACATGGGTCAGTCAGCACTTGCCAGCAGTTGGGGA
GCAGCTTCTAGCCTGGGCACGAAGAGCAGGCACCCCTGAGGAGGGCAGGAGAGTGTCTGGGGTT
CCTGCCCAGCTTGTTACAGGGCAGGCAGTAGGTGTACCTGCCCAGGGACTTGTGGAGTCCTTGA
CCCCGTGTGAGGTGGACGAGGCAGGAAGGACACGAGAATGCACGGAGCCTTCAGGTTAGTGCAA
CCCAGGTCCTGAGTTGAGCTCCTCGATCAACCAAGGACCCTAGAAGATGCTGAGAGAAGAGACT
CTCCCGCCTCAAGTGTCCGGCTGCTGGACAGCACTCCTCAGAGCACCAGCCCCACTGGCTCCCT
GGCACTCTAGTCCCTCAGCTGTGGAAATGAAGGATGACAGGAGACCCACCTGACAGGAATGGTC
TGCAAATGATAGATGCTCAAGAAAGCCACAGAAGCAGGACTCGCCACCCTCTGGGGCGCAGTCA
GTCGCCAGCATGCCAGCCTCATGGTGGCAAGACACTGCCAGCAGCACTTTGCACTCTGATGACC
TCAAAGCACTTTCCTGGCTGCCTTCCAGCAGGGCACTGGCTCTGCATGGTCACAAGCAAGCCAG
GGGATGGGGAAGGGACTGTCTCGACCCATCATCCACACAGGCTTGAGCCCCTCAAGCTTCTTTC
AGATGTAAAATGAGCACCCCCAACCCCATTGCCCTAGCTGGGGCTTCTCCTGGTGGGACTTGGA
AATGGCTGCTTAGGACTGACTCATTGTAGCATTAAGTTAACTGTGAATCATTGTAGGGAGGGGC
AGAGACTTCTCCTGTAGAGAAGCTCATTCCCCCGCCCTCACTCGACAGCCAGGATACCGTCCGT
CCCTATATTTGCGTGGATCCAGACTGCTCCTGGCCCCAGTACATGAACCGCAGCCATGGTGCTG
CATTTGGGGTATATCGAGGTCTGTACACAATAAAATTTGGAATGAA

hide sequence

RefSeq Acc Id:

XM_039086417 ⟹ XP_038942345

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	88,665,417 - 88,689,209 (-)	NCBI
mRatBN7.2	10	88,165,349 - 88,189,139 (-)	NCBI

RefSeq Acc Id:

XM_039086418 ⟹ XP_038942346

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	88,677,670 - 88,715,669 (-)	NCBI
mRatBN7.2	10	88,179,274 - 88,215,558 (-)	NCBI

RefSeq Acc Id:

XM_039086419 ⟹ XP_038942347

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	88,665,417 - 88,679,639 (-)	NCBI
mRatBN7.2	10	88,165,349 - 88,177,557 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101771	(Get FASTA)	NCBI Sequence Viewer
	XP_038942345	(Get FASTA)	NCBI Sequence Viewer
	XP_038942346	(Get FASTA)	NCBI Sequence Viewer
	XP_038942347	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM06262	(Get FASTA)	NCBI Sequence Viewer
	EDM06263	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004532
	ENSRNOP00000004532.5

RefSeq Acc Id:

NP_001101771 ⟸ NM_001108301

- UniProtKB:

D3ZTD1 (UniProtKB/TrEMBL), A6HJQ8 (UniProtKB/TrEMBL), A6HJQ9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAVMEVACPGTPGSAVGQQKEFAKAKEKTQSPGKKQSCIFQLEAVEKSPVFCGKWEILNDVITK
GTAKEGSEGGPPAISIIAQAECENSQEFSPTFSERIFIAGSQQYSQSESLDQIPNNVAHATEGK
MARVCRKGKRHSKARKKRRKRRSKSLAQAGVALAKPLPRTPEQESCTIPVQEDESPLGNLYARN
VSQFTKPLKGPGLGHLCFKKQDEGLRPVLPRPELHKLISPLQCLNHVWKLHHPQATGPLPHPTH
PFPFSRMPHPFPFYPLEPWRPYTLNPAFLDKLAAVSGQRPLPGPPHLSKPAYRDSQKPLPGPHL
ESSCLSREALEKVPAEEYLVHALQGSVSSGQAHSLASLAKTWSSGSSKLQRFSPETEDNEGVLL
TEKLKPVDYEYREEVHWMTHQPRVGRGSFGEVHRMKDKQTGFQCAVKKVRLEVFRAEELIACAG
LSSPRIVPLYGAVREGPWVNIFMELLEGGSLGQLIKQKGCLPEDRALYYLGQALEGLEYLHTHR
VLHGDVKADNVLLSSDGSRAALCDFGHALCLQPDGLGKSLLTGDYIPGTETHMAPEVVLGKPCD
AKVDIWSSCCMMLHMLNGCHPWTQYFRGPLCLKIASEPPPVREIPPSCTPLTAQAIQEGLRKEP
IHRASAMELRRKVGKALQEVGGLKSPWKGEYKEPRPPPQDQAPCPQTLHTLPRENPPAKANTDG
APERQPPLPPEPPEPNKAPALNLSKEESGTWEPLPLSSLDPAPAKGPSLPDRRATFPELELQQL
EIELFLNSLSQPFSLEEQEQILSCLSIDSLSLSEDSEKNPSKASQSSRDTLSSGVHSWSSQAEA
RSSSCSMALARGRPTDIPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPATAFSL
VTKDGQPVCYDMEVPDSGIDLQCTLAPDGSFAWAWRVKHGQLENRP

hide sequence

Ensembl Acc Id:

ENSRNOP00000004532 ⟸ ENSRNOT00000004532

RefSeq Acc Id:	XP_038942345 ⟸ XM_039086417
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038942347 ⟸ XM_039086419
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038942346 ⟸ XM_039086418
- Peptide Label:	isoform X2

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZTD1-F1-model_v2	AlphaFold	D3ZTD1	1-942	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697809

Promoter ID:

EPDNEW_R8334

Type:

single initiation site

Name:

Map3k14_1

Description:

mitogen-activated protein kinase kinase kinase 14

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	91,353,570 - 91,353,630	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310487	AgrOrtholog
BioCyc Gene	G2FUF-23049	BioCyc
Ensembl Genes	ENSRNOG00000003278	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000004532	ENTREZGENE
	ENSRNOT00000004532.6	UniProtKB/TrEMBL
Gene3D-CATH	Phosphorylase Kinase, domain 1	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom	UniProtKB/TrEMBL
	M3K14_STKc	UniProtKB/TrEMBL
	MAP_kinase_kinase_kinase	UniProtKB/TrEMBL
	MAPKKK14	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
KEGG Report	rno:360640	UniProtKB/TrEMBL
NCBI Gene	360640	ENTREZGENE
PANTHER	MAP KINASE KINASE KINASE SSK2-RELATED-RELATED	UniProtKB/TrEMBL
	PTHR48016:SF9	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PhenoGen	Map3k14	PhenoGen
PIRSF	MAPKKK14	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000003278	RatGTEx
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	Kinase_like	UniProtKB/TrEMBL
UniProt	A6HJQ8	ENTREZGENE, UniProtKB/TrEMBL
	A6HJQ9	ENTREZGENE, UniProtKB/TrEMBL
	D3ZTD1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Map3k14	mitogen-activated protein kinase kinase kinase 14	Map3k14_predicted	mitogen-activated protein kinase kinase kinase 14 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Map3k14_predicted	mitogen-activated protein kinase kinase kinase 14 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)