Esco2-ps2 (establishment of cohesion 1 homolog 2 (S. cerevisiae), pseudogene 2) - Rat Genome Database

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Gene: Esco2-ps2 (establishment of cohesion 1 homolog 2 (S. cerevisiae), pseudogene 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Esco2-ps2
Name: establishment of cohesion 1 homolog 2 (S. cerevisiae), pseudogene 2
RGD ID: 1310303
Description: Predicted to enable protein-lysine-acetyltransferase activity. Predicted to be involved in mitotic sister chromatid cohesion. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in Roberts syndrome and lung adenocarcinoma. Orthologous to human ESCO2 (establishment of sister chromatid cohesion N-acetyltransferase 2); INTERACTS WITH atrazine.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: AC110315.1; Esco2; Esco2l1; establishment of cohesion 1 homolog 2 (S. cerevisiae); establishment of cohesion 1 homolog 2 (S. cerevisiae)-like 1; LOC290404; rCG52137-like; RGD1310303; similar to 2410004I17Rik protein
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Esco2  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81556,861,717 - 56,865,187 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1556,863,260 - 56,865,044 (-)EnsemblGRCr8
mRatBN7.21550,452,291 - 50,455,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1550,452,312 - 50,455,724 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl1550,452,312 - 50,455,724 (-)NCBImRatBN7.2
UTH_Rnor_SHR_Utx1554,594,401 - 54,597,869 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01555,712,709 - 55,716,177 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01552,544,758 - 52,548,226 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01557,185,438 - 57,188,908 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1557,186,984 - 57,188,723 (-)NCBIrn6Rnor6.0
Rnor_5.01560,897,350 - 60,900,164 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41555,999,481 - 56,001,268 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1550,084,786 - 50,087,877 (-)NCBICelera
RGSC_v3.11556,015,252 - 56,022,642 (-)NCBI
Cytogenetic Map15q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
atrazine  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Esco2-ps2
9 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000045917   ⟹   ENSRNOP00000090628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1550,452,312 - 50,455,724 (-)Ensembl
RefSeq Acc Id: XR_596044
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1550,069,409 - 50,087,878 (-)NCBI
RefSeq Acc Id: XR_596210
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01557,185,439 - 57,188,909 (-)NCBI
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310303 AgrOrtholog
BioCyc Gene G2FUF-13132 BioCyc
Ensembl Genes ENSRNOG00000029520 Ensembl
NCBI Gene 290404 ENTREZGENE
PhenoGen Esco2-ps2 PhenoGen
RatGTEx ENSRNOG00000029520 RatGTEx


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Esco2-ps2  establishment of cohesion 1 homolog 2 (S. cerevisiae), pseudogene 2  AC110315.1    Data merged from RGD:15003756 737654 PROVISIONAL
2019-11-08 AC110315.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2013-05-24 Esco2-ps2  establishment of cohesion 1 homolog 2 (S. cerevisiae), pseudogene 2  LOC100365653  rCG52137-like  Data merged from RGD:2318632 1643240 APPROVED
2011-06-08 Esco2-ps2  establishment of cohesion 1 homolog 2 (S. cerevisiae), pseudogene 2  Esco2l1  establishment of cohesion 1 homolog 2 (S. cerevisiae)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100365653  rCG52137-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-01-23 Esco2l1  establishment of cohesion 1 homolog 2 (S. cerevisiae)-like 1  Esco2  establishment of cohesion 1 homolog 2 (S. cerevisiae)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Esco2  establishment of cohesion 1 homolog 2 (S. cerevisiae)   Esco2_predicted  establishment of cohesion 1 homolog 2 (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Esco2_predicted  establishment of cohesion 1 homolog 2 (S. cerevisiae) (predicted)  RGD1310303_predicted  similar to 2410004I17Rik protein (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1310303_predicted  similar to 2410004I17Rik protein (predicted)  LOC290404_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC290404_predicted  similar to 2410004I17Rik protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL