E2f7 (E2F transcription factor 7) - Rat Genome Database

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Gene: E2f7 (E2F transcription factor 7) Rattus norvegicus
Analyze
Symbol: E2f7
Name: E2F transcription factor 7
RGD ID: 1310258
Description: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; regulation of cell cycle process; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of cell population proliferation and regulation of DNA-templated transcription. Predicted to be located in nuclear speck. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human E2F7 (E2F transcription factor 7); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E2F-7; LOC314818; transcription factor E2F7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,036,881 - 48,079,055 (+)NCBIGRCr8
mRatBN7.2746,150,533 - 46,192,739 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,151,293 - 46,192,734 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx748,049,531 - 48,091,687 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0750,252,659 - 50,294,815 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,030,385 - 50,072,539 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0753,275,659 - 53,318,261 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,275,676 - 53,316,481 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0753,286,853 - 53,328,709 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4749,689,755 - 49,751,823 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1749,710,871 - 49,771,412 (+)NCBI
Celera742,963,883 - 43,003,790 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2-butoxyethanol  (ISO)
2-palmitoylglycerol  (ISO)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium atom  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
cisplatin  (ISO)
cobalt atom  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coptisine  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gallic acid  (ISO)
gentamycin  (EXP)
harmine  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
MeIQx  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
niclosamide  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phosphoramide mustard  (EXP)
picoxystrobin  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
succimer  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trametinib  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
Tungsten carbide  (ISO)
urethane  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12893818   PMID:15133492   PMID:18541936   PMID:22180533   PMID:22516201   PMID:22802528   PMID:22903062   PMID:23064266  


Genomics

Comparative Map Data
E2f7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,036,881 - 48,079,055 (+)NCBIGRCr8
mRatBN7.2746,150,533 - 46,192,739 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,151,293 - 46,192,734 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx748,049,531 - 48,091,687 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0750,252,659 - 50,294,815 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,030,385 - 50,072,539 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0753,275,659 - 53,318,261 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,275,676 - 53,316,481 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0753,286,853 - 53,328,709 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4749,689,755 - 49,751,823 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1749,710,871 - 49,771,412 (+)NCBI
Celera742,963,883 - 43,003,790 (+)NCBICelera
Cytogenetic Map7q22NCBI
E2F7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381277,021,251 - 77,065,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1277,021,248 - 77,065,569 (-)EnsemblGRCh38hg38GRCh38
GRCh371277,415,031 - 77,459,349 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361275,939,157 - 75,983,491 (-)NCBINCBI36Build 36hg18NCBI36
Celera1277,080,472 - 77,124,821 (-)NCBICelera
Cytogenetic Map12q21.2NCBI
HuRef1274,467,815 - 74,512,166 (-)NCBIHuRef
CHM1_11277,380,867 - 77,425,221 (-)NCBICHM1_1
T2T-CHM13v2.01276,999,082 - 77,043,421 (-)NCBIT2T-CHM13v2.0
E2f7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910110,580,799 - 110,623,245 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10110,581,300 - 110,623,245 (+)EnsemblGRCm39 Ensembl
GRCm3810110,745,439 - 110,787,384 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10110,745,439 - 110,787,384 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710110,182,521 - 110,224,440 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610110,149,578 - 110,191,483 (+)NCBIMGSCv36mm8
MGSCv3610110,874,175 - 110,915,960 (+)NCBIMGSCv36mm8
Celera10112,679,553 - 112,721,244 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1057.74NCBI
E2f7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540516,148,480 - 16,186,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540516,148,640 - 16,187,272 (-)NCBIChiLan1.0ChiLan1.0
E2F7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21085,057,718 - 85,102,581 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11285,054,112 - 85,098,451 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01274,540,049 - 74,582,561 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11277,388,950 - 77,433,262 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1277,388,950 - 77,433,262 (-)Ensemblpanpan1.1panPan2
E2F7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11519,856,093 - 19,895,657 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1519,857,227 - 19,895,225 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1520,339,285 - 20,381,001 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01520,194,252 - 20,236,238 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1520,195,500 - 20,234,063 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11519,793,846 - 19,832,959 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01519,851,678 - 19,893,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01519,980,571 - 20,022,547 (-)NCBIUU_Cfam_GSD_1.0
E2f7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494540,476,352 - 40,522,277 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365685,206,135 - 5,244,450 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365685,206,135 - 5,245,324 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
E2F7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5104,127,731 - 104,163,212 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15104,126,924 - 104,163,582 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25109,254,285 - 109,289,365 (+)NCBISscrofa10.2Sscrofa10.2susScr3
E2F7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11172,598,220 - 72,642,366 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1172,599,353 - 72,641,420 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037172,897,900 - 172,942,501 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
E2f7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475021,010,339 - 21,063,757 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475021,010,347 - 21,063,655 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in E2f7
77 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:387
Count of miRNA genes:209
Interacting mature miRNAs:252
Transcripts:ENSRNOT00000031986
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 86 85 54 25 54 6 213 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000031986   ⟹   ENSRNOP00000030798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,151,293 - 46,192,734 (+)Ensembl
Rnor_6.0 Ensembl753,275,676 - 53,316,481 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094983   ⟹   ENSRNOP00000089197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,151,293 - 46,158,768 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104778   ⟹   ENSRNOP00000081093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,151,293 - 46,192,729 (+)Ensembl
RefSeq Acc Id: NM_001108092   ⟹   NP_001101562
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,036,903 - 48,079,055 (+)NCBI
mRatBN7.2746,150,578 - 46,192,734 (+)NCBI
Rnor_6.0753,275,676 - 53,316,481 (+)NCBI
Rnor_5.0753,286,853 - 53,328,709 (+)NCBI
RGSC_v3.4749,689,755 - 49,751,823 (+)RGD
Celera742,963,883 - 43,003,790 (+)RGD
Sequence:
RefSeq Acc Id: XM_006241321   ⟹   XP_006241383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,036,881 - 48,079,055 (+)NCBI
mRatBN7.2746,150,533 - 46,192,739 (+)NCBI
Rnor_6.0753,275,659 - 53,318,261 (+)NCBI
Rnor_5.0753,286,853 - 53,328,709 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001101562   ⟸   NM_001108092
- UniProtKB: D4A4D7 (UniProtKB/Swiss-Prot),   A0A0A0MY02 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241383   ⟸   XM_006241321
- Peptide Label: isoform X1
- UniProtKB: D4A4D7 (UniProtKB/Swiss-Prot),   A0A0A0MY02 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030798   ⟸   ENSRNOT00000031986
Ensembl Acc Id: ENSRNOP00000081093   ⟸   ENSRNOT00000104778
Ensembl Acc Id: ENSRNOP00000089197   ⟸   ENSRNOT00000094983
Protein Domains
E2F/DP family winged-helix DNA-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4D7-F1-model_v2 AlphaFold D4A4D7 1-902 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695185
Promoter ID:EPDNEW_R5710
Type:initiation region
Name:E2f7_1
Description:E2F transcription factor 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0753,275,691 - 53,275,751EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310258 AgrOrtholog
BioCyc Gene G2FUF-34144 BioCyc
Ensembl Genes ENSRNOG00000026252 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000031986.6 UniProtKB/TrEMBL
  ENSRNOT00000094983.1 UniProtKB/TrEMBL
  ENSRNOT00000104778 ENTREZGENE
  ENSRNOT00000104778.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro E2F UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  E2F_WHTH_DNA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:314818 UniProtKB/TrEMBL
NCBI Gene 314818 ENTREZGENE
PANTHER PTHR12081 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR E2F7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam E2F_TDP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen E2f7 PhenoGen
RatGTEx ENSRNOG00000026252 RatGTEx
SMART E2F_TDP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MY02 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GH03_RAT UniProtKB/TrEMBL
  A6IGF0_RAT UniProtKB/TrEMBL
  D4A4D7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 E2f7  E2F transcription factor 7   E2f7_predicted  E2F transcription factor 7 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 E2f7_predicted  E2F transcription factor 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED