Tbxt (T-box transcription factor T) - Rat Genome Database

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Gene: Tbxt (T-box transcription factor T) Rattus norvegicus
Analyze
Symbol: Tbxt
Name: T-box transcription factor T
RGD ID: 1310141
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in cellular response to retinoic acid. Predicted to be located in chromatin; cytoplasm; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in neural tube defect. Orthologous to human TBXT (T-box transcription factor T); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: brachyury; brachyury homolog; brachyury homolog (mouse); LOC292301; T; T brachyury transcription factor; T, brachyury homolog; T, brachyury homolog (mouse)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8154,845,674 - 54,859,340 (-)NCBIGRCr8
mRatBN7.2152,298,104 - 52,309,813 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,298,099 - 52,305,864 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx152,999,608 - 53,007,373 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0158,991,427 - 58,999,192 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,075,196 - 53,082,961 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0152,887,067 - 52,900,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl152,887,067 - 52,894,832 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0154,139,554 - 54,147,385 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4146,937,223 - 46,944,988 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1146,940,188 - 46,947,933 (-)NCBI
Celera148,061,384 - 48,069,149 (-)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IBA,ISO)
cytoplasm  (ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Pre-activation of retinoid signaling facilitates neuronal differentiation of mesenchymal stem cells. Bi Y, etal., Dev Growth Differ. 2010 Jun;52(5):419-31. doi: 10.1111/j.1440-169X.2010.01182.x.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:924142   PMID:7588606   PMID:7589801   PMID:7720590   PMID:7883069   PMID:8155581   PMID:8293872   PMID:8344258   PMID:9420335   PMID:10349618   PMID:11071760   PMID:15384171  
PMID:16801560   PMID:16835439   PMID:17360443   PMID:18462699   PMID:19796622   PMID:20350929   PMID:20809182   PMID:21632880   PMID:22164283   PMID:22611028   PMID:24253444   PMID:38690917  


Genomics

Comparative Map Data
Tbxt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8154,845,674 - 54,859,340 (-)NCBIGRCr8
mRatBN7.2152,298,104 - 52,309,813 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl152,298,099 - 52,305,864 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx152,999,608 - 53,007,373 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0158,991,427 - 58,999,192 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0153,075,196 - 53,082,961 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0152,887,067 - 52,900,691 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl152,887,067 - 52,894,832 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0154,139,554 - 54,147,385 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4146,937,223 - 46,944,988 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1146,940,188 - 46,947,933 (-)NCBI
Celera148,061,384 - 48,069,149 (-)NCBICelera
Cytogenetic Map1q12NCBI
TBXT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386166,157,656 - 166,168,655 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6166,157,656 - 166,168,700 (-)EnsemblGRCh38hg38GRCh38
GRCh376166,571,144 - 166,582,143 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366166,491,076 - 166,502,121 (-)NCBINCBI36Build 36hg18NCBI36
Build 346166,541,496 - 166,552,542NCBI
Celera6167,310,712 - 167,321,757 (-)NCBICelera
Cytogenetic Map6q27NCBI
HuRef6164,037,863 - 164,048,876 (-)NCBIHuRef
CHM1_16166,835,290 - 166,846,303 (-)NCBICHM1_1
T2T-CHM13v2.06167,527,458 - 167,538,457 (-)NCBIT2T-CHM13v2.0
T
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,653,255 - 8,661,328 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,653,255 - 8,661,328 (+)EnsemblGRCm39 Ensembl
GRCm38178,434,423 - 8,442,496 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,434,423 - 8,442,496 (+)EnsemblGRCm38mm10GRCm38
MGSCv37178,627,288 - 8,635,361 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36178,272,597 - 8,280,670 (+)NCBIMGSCv36mm8
Celera178,480,245 - 8,488,318 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map174.92NCBI
Tbxt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543915,676,095 - 15,683,554 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543915,675,680 - 15,683,542 (+)NCBIChiLan1.0ChiLan1.0
TBXT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25186,353,564 - 186,363,413 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16184,249,368 - 184,259,217 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06164,112,117 - 164,122,253 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16169,095,723 - 169,106,595 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6169,095,723 - 169,106,595 (-)Ensemblpanpan1.1panPan2
TBXT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1154,183,495 - 54,192,331 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl154,183,153 - 54,192,352 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha154,970,966 - 54,979,790 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0154,360,266 - 54,369,833 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl154,360,928 - 54,369,833 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1154,257,349 - 54,266,189 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0154,107,519 - 54,116,264 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0154,733,858 - 54,742,687 (-)NCBIUU_Cfam_GSD_1.0
Tbxt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946148,774,775 - 148,782,886 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648916,027,359 - 16,035,041 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648916,027,359 - 16,035,041 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBXT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl12,717,165 - 2,725,601 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.112,717,165 - 2,725,561 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213,857,228 - 3,861,219 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TBXT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11393,854,086 - 93,864,910 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1393,855,534 - 93,864,507 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604065,656,160 - 65,666,958 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbxt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478513,058,444 - 13,066,719 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478513,058,520 - 13,066,607 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tbxt
24 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:151
Count of miRNA genes:103
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000016471
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat

Markers in Region
T  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2152,303,300 - 52,304,181 (+)MAPPERmRatBN7.2
Rnor_6.0152,892,269 - 52,893,149NCBIRnor6.0
Rnor_5.0154,144,756 - 54,145,636UniSTSRnor5.0
RGSC_v3.4146,942,425 - 46,943,305UniSTSRGSC3.4
Celera148,066,586 - 48,067,466UniSTS
Cytogenetic Map1q11UniSTS
T  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2152,304,121 - 52,304,935 (+)MAPPERmRatBN7.2
Rnor_6.0152,893,090 - 52,893,903NCBIRnor6.0
Rnor_5.0154,145,577 - 54,146,390UniSTSRnor5.0
RGSC_v3.4146,943,246 - 46,944,059UniSTSRGSC3.4
Celera148,067,407 - 48,068,220UniSTS
Cytogenetic Map1q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
4 1 6 97 29 36 8 24 8 4 74 37 87 24 60 28

Sequence


Ensembl Acc Id: ENSRNOT00000016471   ⟹   ENSRNOP00000016471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl152,298,099 - 52,305,864 (-)Ensembl
Rnor_6.0 Ensembl152,887,067 - 52,894,832 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110131   ⟹   ENSRNOP00000092633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl152,298,099 - 52,305,864 (-)Ensembl
RefSeq Acc Id: NM_001106209   ⟹   NP_001099679
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,845,674 - 54,853,583 (-)NCBI
mRatBN7.2152,298,104 - 52,306,013 (-)NCBI
Rnor_6.0152,887,067 - 52,894,832 (-)NCBI
Rnor_5.0154,139,554 - 54,147,385 (-)NCBI
RGSC_v3.4146,937,223 - 46,944,988 (-)RGD
Celera148,061,384 - 48,069,149 (-)RGD
Sequence:
RefSeq Acc Id: XM_017588873   ⟹   XP_017444362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,845,674 - 54,859,340 (-)NCBI
mRatBN7.2152,298,104 - 52,309,813 (-)NCBI
Rnor_6.0152,887,447 - 52,900,691 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039103470   ⟹   XP_038959398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,845,674 - 54,859,340 (-)NCBI
mRatBN7.2152,298,104 - 52,309,813 (-)NCBI
RefSeq Acc Id: XM_039103475   ⟹   XP_038959403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,845,674 - 54,859,340 (-)NCBI
mRatBN7.2152,298,104 - 52,309,812 (-)NCBI
RefSeq Acc Id: XM_063282870   ⟹   XP_063138940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8154,845,674 - 54,859,340 (-)NCBI
RefSeq Acc Id: NP_001099679   ⟸   NM_001106209
- UniProtKB: A6KK19 (UniProtKB/TrEMBL),   A6KK20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444362   ⟸   XM_017588873
- Peptide Label: isoform X1
- UniProtKB: D4A4W8 (UniProtKB/TrEMBL),   A6KK20 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016471   ⟸   ENSRNOT00000016471
RefSeq Acc Id: XP_038959398   ⟸   XM_039103470
- Peptide Label: isoform X2
- UniProtKB: A6KK19 (UniProtKB/TrEMBL),   A6KK20 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959403   ⟸   XM_039103475
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AEA5 (UniProtKB/TrEMBL),   A6KK20 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092633   ⟸   ENSRNOT00000110131
RefSeq Acc Id: XP_063138940   ⟸   XM_063282870
- Peptide Label: isoform X1
- UniProtKB: A6KK20 (UniProtKB/TrEMBL),   D4A4W8 (UniProtKB/TrEMBL)
Protein Domains
T-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4W8-F1-model_v2 AlphaFold D4A4W8 1-436 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310141 AgrOrtholog
BioCyc Gene G2FUF-61518 BioCyc
Ensembl Genes ENSRNOG00000012229 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016471.4 UniProtKB/TrEMBL
  ENSRNOT00000110131.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.820 UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/TrEMBL
  T-box_DNA-bd UniProtKB/TrEMBL
  T-box_sf UniProtKB/TrEMBL
  TF_Brachyury UniProtKB/TrEMBL
  TF_T-box UniProtKB/TrEMBL
  TF_T-box_CS UniProtKB/TrEMBL
KEGG Report rno:292301 UniProtKB/TrEMBL
NCBI Gene 292301 ENTREZGENE
PANTHER T-BOX TRANSCRIPTION FACTOR T UniProtKB/TrEMBL
  TF_T-box UniProtKB/TrEMBL
Pfam T-box UniProtKB/TrEMBL
PhenoGen Tbxt PhenoGen
PRINTS BRACHYURY UniProtKB/TrEMBL
  TBOX UniProtKB/TrEMBL
PROSITE TBOX_1 UniProtKB/TrEMBL
  TBOX_2 UniProtKB/TrEMBL
  TBOX_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012229 RatGTEx
SMART TBOX UniProtKB/TrEMBL
Superfamily-SCOP P53_like_DNA_bnd UniProtKB/TrEMBL
UniProt A0A8I6AEA5 ENTREZGENE, UniProtKB/TrEMBL
  A6KK19 ENTREZGENE, UniProtKB/TrEMBL
  A6KK20 ENTREZGENE, UniProtKB/TrEMBL
  D4A4W8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-12-22 Tbxt  T-box transcription factor T  T brachyury transcription factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-08-13 T brachyury transcription factor  brachyury  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-16 brachyury  brachyury homolog (mouse)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-26 brachyury homolog (mouse)  T, brachyury homolog (mouse)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 T, brachyury homolog (mouse)  brachyury  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 brachyury  T_predicted  T, brachyury homolog (mouse) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 T_predicted  T, brachyury homolog (mouse) (predicted)    brachyury (predicted)  Name updated 1299863 APPROVED
2005-01-12 T_predicted  brachyury (predicted)      Symbol and Name status set to approved 70820 APPROVED