Serpinb8 (serpin family B member 8) - Rat Genome Database

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Gene: Serpinb8 (serpin family B member 8) Rattus norvegicus
Analyze
Symbol: Serpinb8
Name: serpin family B member 8
RGD ID: 1309833
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in epithelial cell-cell adhesion. Predicted to be located in cytosol. Predicted to be active in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in peeling skin syndrome 5. Orthologous to human SERPINB8 (serpin family B member 8); INTERACTS WITH (+)-schisandrin B; 3-chloropropane-1,2-diol; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC288937; serine (or cysteine) peptdiase inhibitor, clade B, member 8; serine (or cysteine) peptidase inhibitor, clade B, member 8; serine (or cysteine) proteinase inhibitor, clade B, member 8; serpin B8; serpin peptidase inhibitor, clade B (ovalbumin), member 8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81324,141,557 - 24,164,894 (+)NCBIGRCr8
mRatBN7.21323,626,936 - 23,650,277 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1323,626,945 - 23,650,835 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1324,003,700 - 24,026,951 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01325,288,158 - 25,311,407 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01323,973,889 - 23,997,138 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01327,876,662 - 27,914,038 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1327,889,345 - 27,914,006 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01333,035,661 - 33,058,982 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41313,718,139 - 13,741,460 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11313,689,411 - 13,714,475 (+)NCBI
Celera1323,473,106 - 23,496,452 (+)NCBICelera
Cytogenetic Map13p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
1-nitropyrene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dimethylarsinic acid  (EXP)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
diquat  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP,ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
iron atom  (ISO)
iron(0)  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
Licochalcone B  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
N-Nitrosopyrrolidine  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
trametinib  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8530382   PMID:23533145   PMID:27476651  


Genomics

Comparative Map Data
Serpinb8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81324,141,557 - 24,164,894 (+)NCBIGRCr8
mRatBN7.21323,626,936 - 23,650,277 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1323,626,945 - 23,650,835 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1324,003,700 - 24,026,951 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01325,288,158 - 25,311,407 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01323,973,889 - 23,997,138 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01327,876,662 - 27,914,038 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1327,889,345 - 27,914,006 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01333,035,661 - 33,058,982 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41313,718,139 - 13,741,460 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11313,689,411 - 13,714,475 (+)NCBI
Celera1323,473,106 - 23,496,452 (+)NCBICelera
Cytogenetic Map13p11NCBI
SERPINB8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381863,970,081 - 64,019,779 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1863,970,029 - 64,019,779 (+)EnsemblGRCh38hg38GRCh38
GRCh371861,637,315 - 61,687,013 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361859,788,243 - 59,807,588 (+)NCBINCBI36Build 36hg18NCBI36
Build 341859,788,242 - 59,807,587NCBI
Celera1858,357,699 - 58,377,053 (+)NCBICelera
Cytogenetic Map18q22.1NCBI
HuRef1858,338,377 - 58,357,732 (+)NCBIHuRef
CHM1_11861,633,434 - 61,652,779 (+)NCBICHM1_1
T2T-CHM13v2.01864,175,116 - 64,224,810 (+)NCBIT2T-CHM13v2.0
Serpinb8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391107,517,668 - 107,536,708 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1107,517,736 - 107,538,214 (+)EnsemblGRCm39 Ensembl
GRCm381107,589,926 - 107,608,978 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1107,590,006 - 107,610,484 (+)EnsemblGRCm38mm10GRCm38
MGSCv371109,486,583 - 109,505,555 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361109,417,618 - 109,436,456 (+)NCBIMGSCv36mm8
Celera1110,430,564 - 110,449,516 (+)NCBICelera
Cytogenetic Map1E2.1NCBI
cM Map150.34NCBI
Serpinb8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540247,763,322 - 47,781,523 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540247,761,900 - 47,781,281 (+)NCBIChiLan1.0ChiLan1.0
SERPINB8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21781,454,672 - 81,494,845 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11867,167,662 - 67,484,657 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01857,313,562 - 57,373,502 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11860,634,212 - 60,684,096 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1860,634,206 - 60,669,118 (+)Ensemblpanpan1.1panPan2
SERPINB8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1113,213,506 - 13,223,489 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl113,200,602 - 13,222,943 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha114,174,267 - 14,187,709 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0113,068,163 - 13,082,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl113,068,049 - 13,082,039 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1113,107,196 - 13,120,647 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0113,036,467 - 13,049,898 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0113,285,466 - 13,298,939 (-)NCBIUU_Cfam_GSD_1.0
SERPINB8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1157,820,657 - 157,836,904 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11157,820,641 - 157,836,922 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21175,308,376 - 175,324,323 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103244145
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11815,766,510 - 15,787,350 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1815,765,671 - 15,787,370 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660609,905,719 - 9,926,364 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Serpinb8
198 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:389
Count of miRNA genes:231
Interacting mature miRNAs:263
Transcripts:ENSRNOT00000003274
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134266636Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13599466834535351Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317034Aia9Adjuvant induced arthritis QTL 94.62joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131176653532331607Rat
2317044Aia23Adjuvant induced arthritis QTL 232.3joint integrity trait (VT:0010548)ankle joint diameter (CMO:0002148)131176653532331607Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 5
Low 1 6 21 13 19 13 17 18 6
Below cutoff 2 21 18 10 10 8 10 18 10 16 8

Sequence


RefSeq Acc Id: ENSRNOT00000003274   ⟹   ENSRNOP00000003274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1323,626,945 - 23,649,739 (+)Ensembl
Rnor_6.0 Ensembl1327,889,395 - 27,912,716 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079134   ⟹   ENSRNOP00000074210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1323,626,945 - 23,650,835 (+)Ensembl
Rnor_6.0 Ensembl1327,889,345 - 27,914,006 (+)Ensembl
RefSeq Acc Id: NM_001105948   ⟹   NP_001099418
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81324,141,557 - 24,164,894 (+)NCBI
mRatBN7.21323,626,936 - 23,650,277 (+)NCBI
Rnor_6.01327,889,395 - 27,912,716 (+)NCBI
Rnor_5.01333,035,661 - 33,058,982 (+)NCBI
RGSC_v3.41313,718,139 - 13,741,460 (+)RGD
Celera1323,473,106 - 23,496,452 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001099418 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91759 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003274
  ENSRNOP00000003274.4
  ENSRNOP00000074210.1
RefSeq Acc Id: NP_001099418   ⟸   NM_001105948
- UniProtKB: D3ZHB5 (UniProtKB/TrEMBL),   A6JSW1 (UniProtKB/TrEMBL),   A0A0G2K7H6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074210   ⟸   ENSRNOT00000079134
RefSeq Acc Id: ENSRNOP00000003274   ⟸   ENSRNOT00000003274
Protein Domains
SERPIN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHB5-F1-model_v2 AlphaFold D3ZHB5 1-375 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698757
Promoter ID:EPDNEW_R9281
Type:multiple initiation site
Name:Serpinb8_1
Description:serpin family B member 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01327,889,470 - 27,889,530EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309833 AgrOrtholog
BioCyc Gene G2FUF-18577 BioCyc
Ensembl Genes ENSRNOG00000002396 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003274 ENTREZGENE
  ENSRNOT00000003274.7 UniProtKB/TrEMBL
  ENSRNOT00000079134.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/TrEMBL
  Serpins superfamily UniProtKB/TrEMBL
InterPro Protease_inhib_I4_serpin UniProtKB/TrEMBL
  Protease_inhib_I4_serpin_CS UniProtKB/TrEMBL
  Sepin_dom UniProtKB/TrEMBL
  Serpin_sf UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/TrEMBL
KEGG Report rno:288937 UniProtKB/TrEMBL
NCBI Gene 288937 ENTREZGENE
PANTHER Prot_inh_serpin UniProtKB/TrEMBL
  SERPIN B8 UniProtKB/TrEMBL
Pfam Serpin UniProtKB/TrEMBL
PhenoGen Serpinb8 PhenoGen
PROSITE SERPIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002396 RatGTEx
SMART SERPIN UniProtKB/TrEMBL
Superfamily-SCOP Prot_inh_serpin UniProtKB/TrEMBL
UniProt A0A0G2K7H6 ENTREZGENE, UniProtKB/TrEMBL
  A6JSW1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZHB5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Serpinb8  serpin family B member 8  Serpinb8  serpin peptidase inhibitor, clade B (ovalbumin), member 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-04-30 Serpinb8  serpin peptidase inhibitor, clade B (ovalbumin), member 8  Serpinb8  serine (or cysteine) peptdiase inhibitor, clade B, member 8   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Serpinb8  serine (or cysteine) peptdiase inhibitor, clade B, member 8   Serpinb8_predicted  serine (or cysteine) peptdiase inhibitor, clade B, member 8 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Serpinb8_predicted  serine (or cysteine) peptdiase inhibitor, clade B, member 8 (predicted)    serine (or cysteine) proteinase inhibitor, clade B, member 8 (predicted)  Name updated 1299863 APPROVED
2005-01-12 Serpinb8_predicted  serine (or cysteine) proteinase inhibitor, clade B, member 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED