Eed (embryonic ectoderm development) - Rat Genome Database

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Gene: Eed (embryonic ectoderm development) Rattus norvegicus
Analyze
Symbol: Eed
Name: embryonic ectoderm development
RGD ID: 1309782
Description: Enables chromatin binding activity. Involved in negative regulation of transcription by RNA polymerase II and spinal cord development. Predicted to be located in cytosol; nucleoplasm; and pronucleus. Predicted to be part of ESC/E(Z) complex; chromatin silencing complex; and sex chromatin. Used to study transient cerebral ischemia. Orthologous to human EED (embryonic ectoderm development); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC293104; polycomb protein EED
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81153,280,419 - 153,307,537 (-)NCBIGRCr8
mRatBN7.21143,867,875 - 143,895,008 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1143,867,875 - 143,894,974 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1151,808,615 - 151,835,700 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01158,985,009 - 159,012,094 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01151,858,916 - 151,886,001 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01154,189,252 - 154,216,340 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1154,189,260 - 154,216,340 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01160,493,753 - 160,520,834 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41146,563,961 - 146,591,042 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11146,642,345 - 146,669,450 (-)NCBI
Celera1142,108,258 - 142,135,298 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi. Gu L, etal., J Neuroinflammation. 2013 Sep 3;10:109. doi: 10.1186/1742-2094-10-109.
4. SET for life: biochemical activities and biological functions of SET domain-containing proteins. Herz HM, etal., Trends Biochem Sci. 2013 Dec;38(12):621-39. doi: 10.1016/j.tibs.2013.09.004. Epub 2013 Oct 20.
5. Epigenetic control of female puberty. Lomniczi A, etal., Nat Neurosci. 2013 Mar;16(3):281-9. doi: 10.1038/nn.3319. Epub 2013 Jan 27.
6. Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes. Metsuyanim S, etal., Stem Cells. 2008 Jul;26(7):1808-17. doi: 10.1634/stemcells.2007-0322. Epub 2008 May 8.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Simon JA and Kingston RE, Mol Cell. 2013 Mar 7;49(5):808-24. doi: 10.1016/j.molcel.2013.02.013.
10. Polycomb group proteins are essential for spinal cord development. Wang C, etal., Front Biosci (Landmark Ed). 2010 Jun 1;15:1018-22.
Additional References at PubMed
PMID:9584197   PMID:11124122   PMID:11555636   PMID:12477932   PMID:12627233   PMID:12900441   PMID:15385962   PMID:15525528   PMID:15916951   PMID:16687444   PMID:17107999   PMID:17997413  
PMID:18483221   PMID:19796622   PMID:20064375   PMID:20064376   PMID:20075857   PMID:20144788   PMID:20439489   PMID:22438827   PMID:22573614   PMID:23104054   PMID:23273982   PMID:24105743  
PMID:26658965   PMID:28041882   PMID:28229514   PMID:31451685   PMID:33479437  


Genomics

Comparative Map Data
Eed
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81153,280,419 - 153,307,537 (-)NCBIGRCr8
mRatBN7.21143,867,875 - 143,895,008 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1143,867,875 - 143,894,974 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1151,808,615 - 151,835,700 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01158,985,009 - 159,012,094 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01151,858,916 - 151,886,001 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01154,189,252 - 154,216,340 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1154,189,260 - 154,216,340 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01160,493,753 - 160,520,834 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41146,563,961 - 146,591,042 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11146,642,345 - 146,669,450 (-)NCBI
Celera1142,108,258 - 142,135,298 (-)NCBICelera
Cytogenetic Map1q32NCBI
EED
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381186,244,753 - 86,287,615 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1186,201,212 - 86,278,813 (+)EnsemblGRCh38hg38GRCh38
GRCh371185,955,795 - 85,989,852 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361185,633,463 - 85,667,429 (+)NCBINCBI36Build 36hg18NCBI36
Build 341185,633,462 - 85,667,426NCBI
Celera1183,265,529 - 83,300,439 (+)NCBICelera
Cytogenetic Map11q14.2NCBI
HuRef1182,243,000 - 82,278,147 (+)NCBIHuRef
CHM1_11185,841,580 - 85,875,590 (+)NCBICHM1_1
T2T-CHM13v2.01186,186,227 - 86,228,460 (+)NCBIT2T-CHM13v2.0
Eed
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39789,603,862 - 89,630,184 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl789,603,862 - 89,630,191 (-)EnsemblGRCm39 Ensembl
GRCm38789,954,654 - 89,980,976 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl789,954,654 - 89,980,983 (-)EnsemblGRCm38mm10GRCm38
MGSCv37797,103,164 - 97,129,486 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36789,829,868 - 89,857,005 (-)NCBIMGSCv36mm8
Celera787,275,683 - 87,302,613 (-)NCBICelera
Cytogenetic Map7D3NCBI
cM Map750.42NCBI
Eed
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554146,659,055 - 6,685,530 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554146,659,144 - 6,685,530 (-)NCBIChiLan1.0ChiLan1.0
EED
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2987,159,183 - 87,197,608 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11188,210,050 - 88,248,464 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01181,295,068 - 81,330,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11184,902,330 - 84,937,906 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1184,902,330 - 84,937,906 (+)Ensemblpanpan1.1panPan2
EED
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12113,260,062 - 13,289,511 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2113,260,002 - 13,289,337 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2113,125,575 - 13,155,433 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02113,442,739 - 13,472,602 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2113,442,743 - 13,472,368 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12113,228,555 - 13,258,431 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02113,300,989 - 13,331,006 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02113,357,756 - 13,387,545 (-)NCBIUU_Cfam_GSD_1.0
Eed
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494772,451,606 - 72,483,821 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649814,051,045 - 14,083,570 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649814,050,731 - 14,082,410 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EED
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl920,123,857 - 20,158,816 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1920,123,077 - 20,158,747 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2922,382,548 - 22,417,549 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EED
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1177,496,266 - 77,531,439 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl177,496,086 - 77,531,499 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604348,194,395 - 48,229,592 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eed
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248453,679,096 - 3,712,176 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248453,679,163 - 3,712,153 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eed
155 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:53
Count of miRNA genes:42
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000024082
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
61346Rf2Renal disease susceptibility QTL 23.7urine protein amount (VT:0005160)urine protein level (CMO:0000591)199267916144267916Rat
61399Tcat1Tongue tumor resistance QTL 13.3tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)199267916144267916Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
2317833Alcrsp19Alcohol response QTL 1912.40.001response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
1641897Alcrsp1Alcohol response QTL 1response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
2303591Gluco41Glucose level QTL 412blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1102168504147168504Rat
61370Mcs3Mammary carcinoma susceptibility QTL 32.15mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1102268556147268556Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1102813953151162766Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1103111621148111621Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1103111621148111621Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1106047847151047847Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
2313060Bss71Bone structure and strength QTL 712.60.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1118944747163944747Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121833674166833674Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501168883176Rat
9685799Bp375Blood pressure QTL 375arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
631202Gluco13Glucose level QTL 130.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1131763437159756369Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1136745990163747690Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 47 31 19 31 8 9 74 35 40 11 8
Low 8 10 10 10 2 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000024082   ⟹   ENSRNOP00000024082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1143,867,878 - 143,894,958 (-)Ensembl
Rnor_6.0 Ensembl1154,189,260 - 154,216,340 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114221   ⟹   ENSRNOP00000093078
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1143,867,875 - 143,894,269 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115575   ⟹   ENSRNOP00000096570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1143,867,917 - 143,894,958 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117476   ⟹   ENSRNOP00000085082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1143,867,879 - 143,894,974 (-)Ensembl
RefSeq Acc Id: NM_001106278   ⟹   NP_001099748
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,280,419 - 153,307,500 (-)NCBI
mRatBN7.21143,867,875 - 143,894,958 (-)NCBI
Rnor_6.01154,189,259 - 154,216,340 (-)NCBI
Rnor_5.01160,493,753 - 160,520,834 (-)NCBI
RGSC_v3.41146,563,961 - 146,591,042 (-)RGD
Celera1142,108,258 - 142,135,298 (-)RGD
Sequence:
RefSeq Acc Id: XM_006229664   ⟹   XP_006229726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,280,735 - 153,307,537 (-)NCBI
mRatBN7.21143,867,875 - 143,895,006 (-)NCBI
Rnor_6.01154,189,252 - 154,216,119 (-)NCBI
Rnor_5.01160,493,753 - 160,520,834 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105860   ⟹   XP_038961788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,280,475 - 153,306,914 (-)NCBI
mRatBN7.21143,867,875 - 143,894,339 (-)NCBI
RefSeq Acc Id: XM_039105864   ⟹   XP_038961792
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,280,475 - 153,307,537 (-)NCBI
mRatBN7.21143,867,875 - 143,895,008 (-)NCBI
RefSeq Acc Id: NP_001099748   ⟸   NM_001106278
- UniProtKB: B5DF02 (UniProtKB/TrEMBL),   F1LMC5 (UniProtKB/TrEMBL),   A0A8I6A2I3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229726   ⟸   XM_006229664
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AQZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024082   ⟸   ENSRNOT00000024082
RefSeq Acc Id: XP_038961792   ⟸   XM_039105864
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A2I3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961788   ⟸   XM_039105860
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AJ96 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000093078   ⟸   ENSRNOT00000114221
RefSeq Acc Id: ENSRNOP00000096570   ⟸   ENSRNOT00000115575
RefSeq Acc Id: ENSRNOP00000085082   ⟸   ENSRNOT00000117476

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DF02-F1-model_v2 AlphaFold B5DF02 1-441 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690185
Promoter ID:EPDNEW_R710
Type:multiple initiation site
Name:Eed_1
Description:embryonic ectoderm development
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01154,216,356 - 154,216,416EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309782 AgrOrtholog
BioCyc Gene G2FUF-58545 BioCyc
Ensembl Genes ENSRNOG00000017509 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024082 ENTREZGENE
  ENSRNOT00000024082.7 UniProtKB/TrEMBL
  ENSRNOT00000114221.1 UniProtKB/TrEMBL
  ENSRNOT00000115575.1 UniProtKB/TrEMBL
  ENSRNOT00000117476.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:293104 UniProtKB/TrEMBL
NCBI Gene 293104 ENTREZGENE
PANTHER POLYCOMB PROTEIN UniProtKB/TrEMBL
  PTHR10253:SF5 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PhenoGen Eed PhenoGen
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017509 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A8I6A2I3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AJ96 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQZ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8YPE2_RAT UniProtKB/TrEMBL
  B5DF02 ENTREZGENE, UniProtKB/TrEMBL
  F1LMC5 ENTREZGENE
UniProt Secondary F1LMC5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Eed  embryonic ectoderm development   Eed_predicted  embryonic ectoderm development (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Eed_predicted  embryonic ectoderm development (predicted)      Symbol and Name status set to approved 70820 APPROVED