Prxl2a (peroxiredoxin like 2A) - Rat Genome Database

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Gene: Prxl2a (peroxiredoxin like 2A) Rattus norvegicus
Analyze
Symbol: Prxl2a
Name: peroxiredoxin like 2A
RGD ID: 1309676
Description: Predicted to enable antioxidant activity. Predicted to be involved in regulation of osteoclast differentiation. Predicted to be located in extracellular region and membrane. Predicted to be active in cytoplasm. Orthologous to human PRXL2A (peroxiredoxin like 2A); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fam213a; family with sequence similarity 213, member A; hypothetical protein LOC361118; LOC361118; PAMM; peroxiredoxin-like 2 activated in M-CSF stimulated monocytes; peroxiredoxin-like 2A; redox-regulatory protein FAM213A; redox-regulatory protein PAMM; RGD1309676; similar to RIKEN cDNA 5730469M10; sperm head protein 1; UPF0765 protein C10orf58 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81616,900,697 - 16,920,521 (-)NCBIGRCr8
mRatBN7.21616,866,601 - 16,886,378 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1616,866,603 - 16,886,433 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1616,930,779 - 16,950,429 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,057,541 - 18,077,191 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01616,983,676 - 17,003,327 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01617,494,000 - 17,513,781 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1617,493,953 - 17,513,870 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01617,376,841 - 17,396,622 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41617,425,527 - 17,445,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11617,425,526 - 17,445,306 (-)NCBI
Celera1617,092,238 - 17,112,513 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
clofibric acid  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
haloperidol  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
potassium chromate  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
tributylstannane  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
extracellular region  (IEA)
membrane  (IEA)

Molecular Function
antioxidant activity  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:18614015   PMID:19951071   PMID:23376485   PMID:29476059  


Genomics

Comparative Map Data
Prxl2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81616,900,697 - 16,920,521 (-)NCBIGRCr8
mRatBN7.21616,866,601 - 16,886,378 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1616,866,603 - 16,886,433 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1616,930,779 - 16,950,429 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01618,057,541 - 18,077,191 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01616,983,676 - 17,003,327 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01617,494,000 - 17,513,781 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1617,493,953 - 17,513,870 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01617,376,841 - 17,396,622 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41617,425,527 - 17,445,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11617,425,526 - 17,445,306 (-)NCBI
Celera1617,092,238 - 17,112,513 (-)NCBICelera
Cytogenetic Map16p14NCBI
PRXL2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381080,407,829 - 80,437,115 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1080,407,829 - 80,437,115 (+)EnsemblGRCh38hg38GRCh38
GRCh371082,167,585 - 82,196,871 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361082,158,222 - 82,182,733 (+)NCBINCBI36Build 36hg18NCBI36
Build 341082,158,277 - 82,182,727NCBI
Celera1076,158,574 - 76,183,083 (+)NCBICelera
Cytogenetic Map10q23.1NCBI
HuRef1076,010,785 - 76,035,953 (+)NCBIHuRef
CHM1_11082,450,611 - 82,475,759 (+)NCBICHM1_1
T2T-CHM13v2.01081,276,927 - 81,306,214 (+)NCBIT2T-CHM13v2.0
Prxl2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391440,715,692 - 40,735,790 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1440,715,697 - 40,735,745 (-)EnsemblGRCm39 Ensembl
GRCm381440,993,735 - 41,013,833 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1440,993,740 - 41,013,788 (-)EnsemblGRCm38mm10GRCm38
MGSCv371441,807,029 - 41,827,064 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361439,902,453 - 39,922,488 (-)NCBIMGSCv36mm8
Celera1437,152,444 - 37,172,479 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1422.36NCBI
Prxl2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955510400,469 - 423,056 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955510400,454 - 420,900 (+)NCBIChiLan1.0ChiLan1.0
PRXL2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2892,374,121 - 92,398,591 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11092,379,450 - 92,403,912 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01076,808,869 - 76,837,447 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11080,407,861 - 80,432,032 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1080,412,903 - 80,432,032 (+)Ensemblpanpan1.1panPan2
PRXL2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1429,539,182 - 29,559,353 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl429,538,781 - 29,558,961 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha429,664,527 - 29,684,707 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0429,842,305 - 29,862,483 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1429,711,907 - 29,732,079 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0429,914,243 - 29,934,411 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0430,268,661 - 30,288,845 (+)NCBIUU_Cfam_GSD_1.0
Prxl2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721351,144,036 - 51,163,838 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936716246,345 - 266,531 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936716246,735 - 266,513 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRXL2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1482,249,452 - 82,271,214 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11482,249,450 - 82,271,227 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21488,856,827 - 88,878,595 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRXL2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1951,403,837 - 51,428,015 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl951,404,808 - 51,427,599 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604811,725,400 - 11,751,897 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prxl2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248416,671,604 - 6,682,854 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248416,672,204 - 6,690,991 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Prxl2a
91 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:296
Count of miRNA genes:199
Interacting mature miRNAs:234
Transcripts:ENSRNOT00000014819
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16422773017696785Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat

Markers in Region
RH134489  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2161,504,078 - 1,504,283 (-)MAPPERmRatBN7.2
Rnor_6.0163,820,918 - 3,821,122NCBIRnor6.0
Rnor_5.0163,786,961 - 3,787,165UniSTSRnor5.0
RGSC_v3.4161,542,394 - 1,542,598UniSTSRGSC3.4
Celera161,479,882 - 1,480,086UniSTS
Cytogenetic Map16p16UniSTS
BI286434  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21616,866,666 - 16,866,835 (-)MAPPERmRatBN7.2
Rnor_6.01617,513,548 - 17,513,719NCBIRnor6.0
Rnor_5.01617,396,389 - 17,396,560UniSTSRnor5.0
RGSC_v3.41617,425,589 - 17,425,760UniSTSRGSC3.4
Celera1617,092,300 - 17,092,471UniSTS
RH 3.4 Map16164.11UniSTS
Cytogenetic Map16p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 14 57 41 19 41 5 5 74 35 41 11 5
Low 29 3 6 3
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000014819   ⟹   ENSRNOP00000014819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1616,866,603 - 16,886,433 (-)Ensembl
Rnor_6.0 Ensembl1617,493,953 - 17,513,870 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113272   ⟹   ENSRNOP00000078597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1616,866,603 - 16,880,274 (-)Ensembl
RefSeq Acc Id: NM_001014140   ⟹   NP_001014162
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81616,900,697 - 16,920,478 (-)NCBI
mRatBN7.21616,866,601 - 16,886,378 (-)NCBI
Rnor_6.01617,494,000 - 17,513,781 (+)NCBI
Rnor_5.01617,376,841 - 17,396,622 (+)NCBI
RGSC_v3.41617,425,527 - 17,445,308 (-)RGD
Celera1617,092,238 - 17,112,513 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252791   ⟹   XP_006252853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81616,900,697 - 16,914,486 (-)NCBI
mRatBN7.21616,866,601 - 16,880,389 (-)NCBI
Rnor_6.01617,500,028 - 17,513,781 (+)NCBI
Rnor_5.01617,376,841 - 17,396,622 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063275493   ⟹   XP_063131563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81616,900,697 - 16,920,521 (-)NCBI
RefSeq Acc Id: NP_001014162   ⟸   NM_001014140
- UniProtKB: P85300 (UniProtKB/Swiss-Prot),   Q6AXX6 (UniProtKB/Swiss-Prot),   A6K9L0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252853   ⟸   XM_006252791
- Peptide Label: isoform X2
- UniProtKB: P85300 (UniProtKB/Swiss-Prot),   Q6AXX6 (UniProtKB/Swiss-Prot),   A6K9L0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014819   ⟸   ENSRNOT00000014819
RefSeq Acc Id: ENSRNOP00000078597   ⟸   ENSRNOT00000113272
RefSeq Acc Id: XP_063131563   ⟸   XM_063275493
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G216 (UniProtKB/TrEMBL),   A0A8L2Q6Y2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXX6-F1-model_v2 AlphaFold Q6AXX6 1-229 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699968
Promoter ID:EPDNEW_R10491
Type:initiation region
Name:Fam213a_1
Description:family with sequence similarity 213, member A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01617,493,962 - 17,494,022EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309676 AgrOrtholog
BioCyc Gene G2FUF-11913 BioCyc
Ensembl Genes ENSRNOG00000011140 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014819.6 UniProtKB/TrEMBL
  ENSRNOT00000113272.1 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7134042 IMAGE-MGC_LOAD
InterPro PXL2A/B/C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361118 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94395 IMAGE-MGC_LOAD
NCBI Gene 361118 ENTREZGENE
PANTHER PEROXIREDOXIN-LIKE 2A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR28630 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AhpC-TSA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prxl2a PhenoGen
RatGTEx ENSRNOG00000011140 RatGTEx
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6G216 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q6Y2 ENTREZGENE, UniProtKB/TrEMBL
  A6K9L0 ENTREZGENE, UniProtKB/TrEMBL
  P85300 ENTREZGENE
  PXL2A_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P85300 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-07-26 Prxl2a  peroxiredoxin like 2A  Fam213a  family with sequence similarity 213, member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-10 Fam213a  family with sequence similarity 213, member A  RGD1309676  similar to RIKEN cDNA 5730469M10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1309676  similar to RIKEN cDNA 5730469M10  RGD1309676_predicted  similar to RIKEN cDNA 5730469M10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1309676_predicted  similar to RIKEN cDNA 5730469M10 (predicted)  LOC361118_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361118_predicted  similar to RIKEN cDNA 5730469M10 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL