P4ha2 (prolyl 4-hydroxylase subunit alpha 2)

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Gene: P4ha2 (prolyl 4-hydroxylase subunit alpha 2) Rattus norvegicus

Analyze

Symbol:

P4ha2

Name:

prolyl 4-hydroxylase subunit alpha 2

RGD ID:

1309673

Description:

Predicted to enable procollagen-proline 4-dioxygenase activity. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of procollagen-proline 4-dioxygenase complex. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in myopia. Orthologous to human P4HA2 (prolyl 4-hydroxylase subunit alpha 2); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC360526; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II; prolyl 4-hydroxylase subunit alpha-2; prolyl 4-hydroxylase, alpha polypeptide II

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	38,243,139 - 38,287,314 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	42,928,504 - 42,957,355 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	42,418,604 - 42,447,453 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	37,922,310 - 37,951,165 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	39,435,227 - 39,464,134 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	39,435,227 - 39,464,188 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	39,214,791 - 39,243,698 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	39,522,157 - 39,551,063 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	39,535,833 - 39,564,271 (+)	NCBI
Celera	10	37,584,460 - 37,613,368 (+)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

familial adenomatous polyposis 1 (ISO)

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Myopia 25, Autosomal Dominant (ISO)

Neurodevelopmental Disorders (ISO)

schizophrenia (ISO)

systemic primary carnitine deficiency disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,10-phenanthroline (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

5-chloro-7-iodoquinolin-8-ol (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

atrazine (EXP,ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

cadmium dichloride (EXP,ISO)

calciol (ISO)

calcium silicate (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (EXP,ISO)

cyclosporin A (ISO)

cytarabine (ISO)

dexamethasone (ISO)

diclofenac (ISO)

dioxygen (ISO)

diquat (ISO)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (ISO)

fluoranthene (ISO)

folic acid (ISO)

ivermectin (ISO)

L-ascorbic acid (ISO)

L-methionine (ISO)

lead(0) (ISO)

methamphetamine (EXP)

nickel dichloride (EXP,ISO)

nickel subsulfide (ISO)

nickel sulfate (ISO)

oxaliplatin (EXP,ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

potassium dichromate (EXP)

progesterone (ISO)

propiconazole (ISO)

SB 431542 (ISO)

SCH 23390 (EXP)

serpentine asbestos (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

tetrachloromethane (EXP,ISO)

thifluzamide (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc dichloride (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytosol (IEA,ISO)

endoplasmic reticulum (IBA,ISO)

endoplasmic reticulum lumen (IEA)

intracellular membrane-bounded organelle (ISO)

nucleoplasm (IEA,ISO)

procollagen-proline 4-dioxygenase complex (ISO)

Molecular Function

iron ion binding (IEA)

L-ascorbic acid binding (IEA)

procollagen-proline 4-dioxygenase activity (IBA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

arginine and proline metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7753822

Genomics

Comparative Map Data

P4ha2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	38,243,139 - 38,287,314 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	42,928,504 - 42,957,355 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	42,418,604 - 42,447,453 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	37,922,310 - 37,951,165 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	39,435,227 - 39,464,134 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	39,435,227 - 39,464,188 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	39,214,791 - 39,243,698 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	39,522,157 - 39,551,063 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	39,535,833 - 39,564,271 (+)	NCBI
Celera	10	37,584,460 - 37,613,368 (+)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

P4HA2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	132,190,147 - 132,227,853 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	132,190,147 - 132,295,315 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	131,525,840 - 131,563,546 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	131,556,202 - 131,591,455 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	131,556,201 - 131,590,458	NCBI
Celera	5	127,658,410 - 127,693,660 (-)	NCBI		Celera
Cytogenetic Map	5	q31.1	NCBI
HuRef	5	126,720,651 - 126,756,017 (-)	NCBI		HuRef
CHM1_1	5	130,961,055 - 130,996,320 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	132,710,021 - 132,747,731 (-)	NCBI		T2T-CHM13v2.0

P4ha2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	53,991,750 - 54,022,494 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	53,990,921 - 54,022,491 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	54,100,924 - 54,131,668 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	54,100,095 - 54,131,665 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	53,914,426 - 53,945,169 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	53,944,939 - 53,975,071 (+)	NCBI		MGSCv36	mm8
Celera	11	58,688,554 - 58,719,297 (+)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	32.13	NCBI

P4ha2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	3,574,860 - 3,607,015 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	3,574,860 - 3,607,015 (-)	NCBI	ChiLan1.0	ChiLan1.0

P4HA2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	5	125,583,719 - 125,685,655 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	127,613,037 - 127,650,647 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	133,778,520 - 133,813,779 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	133,778,520 - 133,813,779 (-)	Ensembl	panpan1.1		panPan2

P4HA2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	20,514,982 - 20,548,261 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	20,514,978 - 20,549,541 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	19,310,369 - 19,350,017 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	21,300,346 - 21,333,655 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	21,300,356 - 21,333,637 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	20,019,425 - 20,052,694 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	19,867,545 - 19,900,820 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	20,509,393 - 20,542,685 (-)	NCBI		UU_Cfam_GSD_1.0

P4ha2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	115,927,933 - 115,960,406 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936647	2,930,494 - 2,964,550 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936647	2,930,748 - 2,963,168 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

P4HA2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	134,502,212 - 134,595,430 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	134,502,210 - 134,595,444 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	139,853,792 - 139,886,023 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

P4HA2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	35,022,675 - 35,058,128 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	35,020,535 - 35,058,009 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	42,885,975 - 42,923,550 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

P4ha2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	39,871,180 - 39,903,377 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	39,871,156 - 39,902,266 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in P4ha2
229 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	89
Count of miRNA genes:	74
Interacting mature miRNAs:	87
Transcripts:	ENSRNOT00000042144
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38328221	Rat
7411611	Foco17	Food consumption QTL 17	18.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	1	42315980	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1	80676123	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	418344	45418344	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	743364	63851208	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5387014	50387014	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5387014	50387014	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5387014	50387014	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5387014	50387014	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5387014	50387014	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	5801990	62146030	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6154182	73453136	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6375746	51375746	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
9590310	Scort19	Serum corticosterone level QTL 19	6.3	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9590268	Scort13	Serum corticosterone level QTL 13	3.26	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9589136	Insul27	Insulin level QTL 27	10.46	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	10	11474010	56474010	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15028513	60430477	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15275955	60275955	Rat
6893350	Bw99	Body weight QTL 99	0.87	0.16	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
6893352	Bw100	Body weight QTL 100	0.33	0.6	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	17907113	51786432	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18167841	63167841	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	19606483	64606483	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	19606483	64606483	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21329805	61345413	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	26521957	61345413	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	26944628	71944628	Rat
10402859	Bp381	Blood pressure QTL 381		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
2292441	Bp308	Blood pressure QTL 308			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28453136	73453136	Rat
1600371	Mcs21	Mammary carcinoma susceptibility QTL 21	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	28875650	52200160	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29299504	64155584	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
631557	Bp136	Blood pressure QTL 136		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	30632053	75632053	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31224026	75632053	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31297439	76297439	Rat
1576319	Cia29	Collagen induced arthritis QTL 29			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	33973921	78973921	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	34490559	45579777	Rat
1354614	Hpcl1	Hepatic cholesterol level QTL 1	3.3		liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	35392267	51793994	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35392267	64155584	Rat
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35392457	63642539	Rat
2317042	Aia20	Adjuvant induced arthritis QTL 20	3.38		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	37565079	82565079	Rat
2317043	Aia7	Adjuvant induced arthritis QTL 7	3.82		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	37565079	82565079	Rat

Markers in Region

BI276296

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	38,271,750 - 38,271,913 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	39,463,896 - 39,464,058	NCBI	Rnor6.0
Rnor_5.0	10	39,243,460 - 39,243,622	UniSTS	Rnor5.0
RGSC_v3.4	10	39,550,825 - 39,550,987	UniSTS	RGSC3.4
Celera	10	37,613,130 - 37,613,292	UniSTS
RH 3.4 Map	10	413.5	UniSTS
Cytogenetic Map	10	q22	UniSTS

UniSTS:546912

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	38,271,480 - 38,271,917 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	39,463,626 - 39,464,062	NCBI	Rnor6.0
Rnor_5.0	10	39,243,190 - 39,243,626	UniSTS	Rnor5.0
Celera	10	37,612,860 - 37,613,296	UniSTS
Cytogenetic Map	10	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		29	30	22	1	22	5	8	36	35	41	11	5
Low	3	14	27	19	18	19	3	3	38				3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399543	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000042144 ⟹ ENSRNOP00000048172

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	38,243,142 - 38,271,990 (+)	Ensembl
Rnor_6.0 Ensembl	10	39,435,227 - 39,464,134 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000077185 ⟹ ENSRNOP00000070701

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	38,243,139 - 38,271,991 (+)	Ensembl
Rnor_6.0 Ensembl	10	39,435,283 - 39,464,188 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104075 ⟹ ENSRNOP00000089755

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	38,243,196 - 38,271,967 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106136 ⟹ ENSRNOP00000097385

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	38,243,175 - 38,287,314 (+)	Ensembl

RefSeq Acc Id:

NM_001108275 ⟹ NP_001101745

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI
Rnor_6.0	10	39,435,227 - 39,464,134 (+)	NCBI
Rnor_5.0	10	39,214,791 - 39,243,698 (+)	NCBI
RGSC_v3.4	10	39,522,157 - 39,551,063 (+)	RGD
Celera	10	37,584,460 - 37,613,368 (+)	RGD

Sequence:

show sequence

GCGGGAGGTGGGGATCGTGGCGGAGGCTCAAGCAGGCGGAGCTTCTGACGAGGGCGGAGCCGAG
AGCGCCCGGGCGACGCCGCGGGAGGTTCTGGAAACGCCGGCTGCTGCGCGTGTCCAGTTTCAGA
GACCGGTGGCGATTGGCTGACTGATTCAACAAATAGAGCATTCTCTGTGCCTGGAGACTTTCAA
GGACGGAGGCAGGCAGAAGGGAAGACTCAGAAAGTCCGTGTCCAGAGCACCGGCAAGGTCCCGC
CCTTTCCAGTCATGAAGCTCCAGGTGTTGGTGTTGCTGATGTCCTGGTTTGGTGTCCTGAGCTG
GGTGCAGGCGGAATTCTTCACCTCCATTGGGCACATGACCGACCTGATTTATGCAGAGAAGGAC
CTCGTCCAGTCTCTGAAGGAGTACATCCTGGCAGAGGAAGCCAAGCTCTCCAAGATTAAGAGCT
GGGCCAGTAAGATGGAGGCCCTGACCAGCAAGTCAGCTGCTGACCCCGAGGGCTACCTGGCCCA
TCCTGTGAACGCCTATAAGCTGGTGAAGCGATTGAACACAGACTGGCCTGCCCTGGGGGACCTT
GTCCTCCAGGACGCGGCTGCAGGTTTTGTGGCTAACCTCTCAGTTCAGCGGCAGTTCTTCCCCA
CTGACGAGGACGAGTCTGGAGCTGCCAGAGCCCTGATGCGACTTCAGGACACCTACAAACTGGA
TCCGGACATGATTTCTAGAGGGGAGCTTCCAGGAACAAAGTACCAGGCCATGCTGAGTGTGGAT
GACTGCTTTGGGATGGGCCGCTCAGCTTACAACGAAGGAGACTATTACCACACCGTGTTGTGGA
TGGAGCAGGTGCTGAAGCAGCTGGATGCTGGGGAGGAGGCCACTGTTACCAAATCCCTGGTGCT
GGACTACCTGAGCTATGCCGTCTTCCAGCTGGGTGACCTGCACCGTGCGGTGGAACTCACCCGT
CGCCTGCTCTCTCTTGACCCGAGCCATGAACGAGCCGGAGGGAACCTGCGGTACTTTGAGCGGC
TGTTAGAGGAAGAAAGAGGAAAATCATTGTCGAATCAGACGGACGCTGGACTAGCATCGCAGGA
AAACTTGTACGAGAGGCCTGTAGACTACCTGCCCGAGAGGGACGTGTATGAGAGCCTGTGTCGA
GGGGAGGGCATCAAAATGACACCCCGGAGGCAGAAGAGGCTTTTCTGTAGATACCACCATGGAA
ACAGAGTGCCACAGCTCCTCATTGCCCCCTTCAAAGAGGAAGACGAGTGGGACAGCCCACACAT
CGTCAGGTACTATGATGTGATGTCGGACGAAGAGATCGAGAGGATCAAGGAGATTGCTAAGCCC
AAACTCGCACGAGCCACTGTGCGTGATCCCAAGACAGGTGTCCTCACTGTTGCTAGCTACAGAG
TTTCCAAAAGCTCCTGGCTAGAGGAAGACGATGACCCTGTTGTGGCCCGAGTCAACCGCAGGAT
GCAGCACATCACAGGGCTGACGGTGAAGACTGCAGAGCTATTGCAGGTCGCAAACTACGGAATG
GGGGGACAGTACGAACCACACTTTGACTTCTCGAGGAGCGATGAGCGAGATGCTTTCAAGCGTT
TAGGGACTGGGAACCGTGTGGCCACATTTCTAAACTACATGAGTGATGTTGAAGCTGGTGGCGC
CACTGTCTTCCCCGACTTGGGAGCTGCGATTTGGCCCAAGAAGGGCACGGCTGTATTTTGGTAT
AACCTTCTTCGGAGCGGGGAAGGCGATTATCGAACGAGGCACGCGGCCTGCCCTGTGCTTGTGG
GCTGCAAGTGGGTCTCCAATAAGTGGTTCCATGAGCGAGGACAGGAGTTCTTGAGGCCTTGTGG
GACAACGGAAGTCGATTGACGTCCTTTTCTGCTCTGCCCCTCCCTGTCCCACAGTCCAAATCAT
CTTCAAGTTCAGTGTGACAGCTTCCTTTGTATGTCCCAGCTCCTGTCAAGCAGGCCATTGGGGG
AGCCAGTGTTTGTCTGAATTGAGAGAGTGTGTCCTGAGCCGAGTCCTGGGTGACCTGGGCCGCA
GGCTCTGGCCAGCCTATGCCTGCCCTGGCTCCCAGGGTAGTCTTGTCATGGCTGTAGTAGAGCC
AGACTGTAGCACCCAGCACGGTGCCTTTGTACCTCAGATATTTCAGGTGGACGATGTTTCAGTG
AAACCAAAGTTCTGACACTGTTTACATGTTTGTTTTCTATGACATTTCTATTTGTTGTGGCTTT
AACCAAAAAATAAAATAAAACAAAACAAAACAAAATAAAATGTTCCTGCCAGAAGCCTTAAAGA
GCTTTACTTCGG

hide sequence

RefSeq Acc Id:

NM_001399539 ⟹ NP_001386468

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

NM_001399540 ⟹ NP_001386469

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

NM_001399541 ⟹ NP_001386470

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

NM_001399542 ⟹ NP_001386471

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

NM_001399543 ⟹ NP_001386472

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	38,243,136 - 38,271,983 (+)	NCBI

RefSeq Acc Id:

XM_008767691 ⟹ XP_008765913

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	38,243,280 - 38,271,983 (+)	NCBI
Rnor_6.0	10	39,435,421 - 39,464,128 (+)	NCBI

Sequence:

show sequence

CGCGGAGCCGGGAGCTGGATCCGGGGTCACTCAGTCTCGCTCTCGGCGCCCTGATTCTGCACCC
GCCTGGGTTCCTGTTCCCGCCCGTGTCCCTTCCCAGGGTTAGGGCGGTGAGTTTCAGAGACCGG
TGGCGATTGGCTGACTGATTCAACAAATAGAGCATTCTCTGTGCCTGGAGACTTTCAAGGACGG
AGGCAGGCAGAAGGGAAGACTCAGAAAGTCCGTGTCCAGAGCACCGGCAAGGTCCCGCCCTTTC
CAGTCATGAAGCTCCAGGTGTTGGTGTTGCTGATGTCCTGGTTTGGTGTCCTGAGCTGGGTGCA
GGCGGAATTCTTCACCTCCATTGGGCACATGACCGACCTGATTTATGCAGAGAAGGACCTCGTC
CAGTCTCTGAAGGAGTACATCCTGGCAGAGGAAGCCAAGCTCTCCAAGATTAAGAGCTGGGCCA
GTAAGATGGAGGCCCTGACCAGCAAGTCAGCTGCTGACCCCGAGGGCTACCTGGCCCATCCTGT
GAACGCCTATAAGCTGGTGAAGCGATTGAACACAGACTGGCCTGCCCTGGGGGACCTTGTCCTC
CAGGACGCGGCTGCAGGTTTTGTGGCTAACCTCTCAGTTCAGCGGCAGTTCTTCCCCACTGACG
AGGACGAGTCTGGAGCTGCCAGAGCCCTGATGCGACTTCAGGACACCTACAAACTGGATCCGGA
CATGATTTCTAGAGGGGAGCTTCCAGGAACAAAGTACCAGGCCATGCTGAGTGTGGATGACTGC
TTTGGGATGGGCCGCTCAGCTTACAACGAAGGAGACTATTACCACACCGTGTTGTGGATGGAGC
AGGTGCTGAAGCAGCTGGATGCTGGGGAGGAGGCCACTGTTACCAAATCCCTGGTGCTGGACTA
CCTGAGCTATGCCGTCTTCCAGCTGGGTGACCTGCACCGTGCGGTGGAACTCACCCGTCGCCTG
CTCTCTCTTGACCCGAGCCATGAACGAGCCGGAGGGAACCTGCGGTACTTTGAGCGGCTGTTAG
AGGAAGAAAGAGGAAAATCATTGTCGAATCAGACGGACGCTGGACTAGCATCGCAGGAAAACTT
GTACGAGAGGCCTGTAGACTACCTGCCCGAGAGGGACGTGTATGAGAGCCTGTGTCGAGGGGAG
GGCATCAAAATGACACCCCGGAGGCAGAAGAGGCTTTTCTGTAGATACCACCATGGAAACAGAG
TGCCACAGCTCCTCATTGCCCCCTTCAAAGAGGAAGACGAGTGGGACAGCCCACACATCGTCAG
GTACTATGATGTGATGTCGGACGAAGAGATCGAGAGGATCAAGGAGATTGCTAAGCCCAAACTC
GCACGAGCCACTGTGCGTGATCCCAAGACAGGTGTCCTCACTGTTGCTAGCTACAGAGTTTCCA
AAAGCTCCTGGCTAGAGGAAGACGATGACCCTGTTGTGGCCCGAGTCAACCGCAGGATGCAGCA
CATCACAGGGCTGACGGTGAAGACTGCAGAGCTATTGCAGGTCGCAAACTACGGAATGGGGGGA
CAGTACGAACCACACTTTGACTTCTCGAGGAGCGATGAGCGAGATGCTTTCAAGCGTTTAGGGA
CTGGGAACCGTGTGGCCACATTTCTAAACTACATGAGTGATGTTGAAGCTGGTGGCGCCACTGT
CTTCCCCGACTTGGGAGCTGCGATTTGGCCCAAGAAGGGCACGGCTGTATTTTGGTATAACCTT
CTTCGGAGCGGGGAAGGCGATTATCGAACGAGGCACGCGGCCTGCCCTGTGCTTGTGGGCTGCA
AGTGGGTCTCCAATAAGTGGTTCCATGAGCGAGGACAGGAGTTCTTGAGGCCTTGTGGGACAAC
GGAAGTCGATTGACGTCCTTTTCTGCTCTGCCCCTCCCTGTCCCACAGTCCAAATCATCTTCAA
GTTCAGTGTGACAGCTTCCTTTGTATGTCCCAGCTCCTGTCAAGCAGGCCATTGGGGGAGCCAG
TGTTTGTCTGAATTGAGAGAGTGTGTCCTGAGCCGAGTCCTGGGTGACCTGGGCCGCAGGCTCT
GGCCAGCCTATGCCTGCCCTGGCTCCCAGGGTAGTCTTGTCATGGCTGTAGTAGAGCCAGACTG
TAGCACCCAGCACGGTGCCTTTGTACCTCAGATATTTCAGGTGGACGATGTTTCAGTGAAACCA
AAGTTCTGACACTGTTTACATGTTTGTTTTCTATGACATTTCTATTTGTTGTGGCTTTAACCAA
AAAATAAAATAAAACAAAACAAAACAAAATAAAATGTTCCTGCCAGAAGCCTTAAAGAGCTTTA

hide sequence

RefSeq Acc Id:

XM_017597370 ⟹ XP_017452859

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	38,243,238 - 38,271,983 (+)	NCBI
Rnor_6.0	10	39,435,358 - 39,464,128 (+)	NCBI

Sequence:

show sequence

TCTGCGGGGTCGTCGTCCGGGCTGGCCTCGGGTCCCGGTGACCCGGCGTTTCAGAGACCGGTGG
CGATTGGCTGACTGATTCAACAAATAGAGCATTCTCTGTGCCTGGAGACTTTCAAGGACGGAGG
CAGGCAGAAGGGAAGACTCAGAAAGTCCGTGTCCAGAGCACCGGCAAGGTCCCGCCCTTTCCAG
TCATGAAGCTCCAGGTGTTGGTGTTGCTGATGTCCTGGTTTGGTGTCCTGAGCTGGGTGCAGGC
GGAATTCTTCACCTCCATTGGGCACATGACCGACCTGATTTATGCAGAGAAGGACCTCGTCCAG
TCTCTGAAGGAGTACATCCTGGCAGAGGAAGCCAAGCTCTCCAAGATTAAGAGCTGGGCCAGTA
AGATGGAGGCCCTGACCAGCAAGTCAGCTGCTGACCCCGAGGGCTACCTGGCCCATCCTGTGAA
CGCCTATAAGCTGGTGAAGCGATTGAACACAGACTGGCCTGCCCTGGGGGACCTTGTCCTCCAG
GACGCGGCTGCAGGTTTTGTGGCTAACCTCTCAGTTCAGCGGCAGTTCTTCCCCACTGACGAGG
ACGAGTCTGGAGCTGCCAGAGCCCTGATGCGACTTCAGGACACCTACAAACTGGATCCGGACAT
GATTTCTAGAGGGGAGCTTCCAGGAACAAAGTACCAGGCCATGCTGAGTGTGGATGACTGCTTT
GGGATGGGCCGCTCAGCTTACAACGAAGGAGACTATTACCACACCGTGTTGTGGATGGAGCAGG
TGCTGAAGCAGCTGGATGCTGGGGAGGAGGCCACTGTTACCAAATCCCTGGTGCTGGACTACCT
GAGCTATGCCGTCTTCCAGCTGGGTGACCTGCACCGTGCGGTGGAACTCACCCGTCGCCTGCTC
TCTCTTGACCCGAGCCATGAACGAGCCGGAGGGAACCTGCGGTACTTTGAGCGGCTGTTAGAGG
AAGAAAGAGGAAAATCATTGTCGAATCAGACGGACGCTGGACTAGCATCGCAGGAAAACTTGTA
CGAGAGGCCTGTAGACTACCTGCCCGAGAGGGACGTGTATGAGAGCCTGTGTCGAGGGGAGGGC
ATCAAAATGACACCCCGGAGGCAGAAGAGGCTTTTCTGTAGATACCACCATGGAAACAGAGTGC
CACAGCTCCTCATTGCCCCCTTCAAAGAGGAAGACGAGTGGGACAGCCCACACATCGTCAGGTA
CTATGATGTGATGTCGGACGAAGAGATCGAGAGGATCAAGGAGATTGCTAAGCCCAAACTCGCA
CGAGCCACTGTGCGTGATCCCAAGACAGGTGTCCTCACTGTTGCTAGCTACAGAGTTTCCAAAA
GCTCCTGGCTAGAGGAAGACGATGACCCTGTTGTGGCCCGAGTCAACCGCAGGATGCAGCACAT
CACAGGGCTGACGGTGAAGACTGCAGAGCTATTGCAGGTCGCAAACTACGGAATGGGGGGACAG
TACGAACCACACTTTGACTTCTCGAGGAGCGATGAGCGAGATGCTTTCAAGCGTTTAGGGACTG
GGAACCGTGTGGCCACATTTCTAAACTACATGAGTGATGTTGAAGCTGGTGGCGCCACTGTCTT
CCCCGACTTGGGAGCTGCGATTTGGCCCAAGAAGGGCACGGCTGTATTTTGGTATAACCTTCTT
CGGAGCGGGGAAGGCGATTATCGAACGAGGCACGCGGCCTGCCCTGTGCTTGTGGGCTGCAAGT
GGGTCTCCAATAAGTGGTTCCATGAGCGAGGACAGGAGTTCTTGAGGCCTTGTGGGACAACGGA
AGTCGATTGACGTCCTTTTCTGCTCTGCCCCTCCCTGTCCCACAGTCCAAATCATCTTCAAGTT
CAGTGTGACAGCTTCCTTTGTATGTCCCAGCTCCTGTCAAGCAGGCCATTGGGGGAGCCAGTGT
TTGTCTGAATTGAGAGAGTGTGTCCTGAGCCGAGTCCTGGGTGACCTGGGCCGCAGGCTCTGGC
CAGCCTATGCCTGCCCTGGCTCCCAGGGTAGTCTTGTCATGGCTGTAGTAGAGCCAGACTGTAG
CACCCAGCACGGTGCCTTTGTACCTCAGATATTTCAGGTGGACGATGTTTCAGTGAAACCAAAG
TTCTGACACTGTTTACATGTTTGTTTTCTATGACATTTCTATTTGTTGTGGCTTTAACCAAAAA
ATAAAATAAAACAAAACAAAACAAAATAAAATGTTCCTGCCAGAAGCCTTAAAGAGCTTTA

hide sequence

RefSeq Acc Id:

XM_039086302 ⟹ XP_038942230

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	38,243,196 - 38,271,983 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101745	(Get FASTA)	NCBI Sequence Viewer
	NP_001386468	(Get FASTA)	NCBI Sequence Viewer
	NP_001386469	(Get FASTA)	NCBI Sequence Viewer
	NP_001386470	(Get FASTA)	NCBI Sequence Viewer
	NP_001386471	(Get FASTA)	NCBI Sequence Viewer
	NP_001386472	(Get FASTA)	NCBI Sequence Viewer
	XP_008765913	(Get FASTA)	NCBI Sequence Viewer
	XP_017452859	(Get FASTA)	NCBI Sequence Viewer
	XP_038942230	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM04421	(Get FASTA)	NCBI Sequence Viewer
	EDM04422	(Get FASTA)	NCBI Sequence Viewer
	EDM04423	(Get FASTA)	NCBI Sequence Viewer
	EDM04424	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001101745 ⟸ NM_001108275
- Peptide Label:	isoform 1 precursor
- UniProtKB:	D3ZGT6 (UniProtKB/TrEMBL), A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLQVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASK MEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDED ESGAARALMRLQDTYKLDPDMISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQV LKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEE ERGKSLSNQTDAGLASQENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCRYHHGNRVP QLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKS SWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDERDAFKRLGTG NRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKW VSNKWFHERGQEFLRPCGTTEVD hide sequence

RefSeq Acc Id:	XP_008765913 ⟸ XM_008767691
- Peptide Label:	isoform X1
- UniProtKB:	D3ZGT6 (UniProtKB/TrEMBL), A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLQVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASK MEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDED ESGAARALMRLQDTYKLDPDMISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQV LKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEE ERGKSLSNQTDAGLASQENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCRYHHGNRVP QLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKS SWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDERDAFKRLGTG NRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKW VSNKWFHERGQEFLRPCGTTEVD hide sequence

RefSeq Acc Id:	XP_017452859 ⟸ XM_017597370
- Peptide Label:	isoform X1
- UniProtKB:	D3ZGT6 (UniProtKB/TrEMBL), A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLQVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASK MEALTSKSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDED ESGAARALMRLQDTYKLDPDMISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQV LKQLDAGEEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEE ERGKSLSNQTDAGLASQENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCRYHHGNRVP QLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKS SWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDERDAFKRLGTG NRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKW VSNKWFHERGQEFLRPCGTTEVD hide sequence

RefSeq Acc Id:

ENSRNOP00000070701 ⟸ ENSRNOT00000077185

RefSeq Acc Id:

ENSRNOP00000048172 ⟸ ENSRNOT00000042144

RefSeq Acc Id:	XP_038942230 ⟸ XM_039086302
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000089755 ⟸ ENSRNOT00000104075

RefSeq Acc Id:

ENSRNOP00000097385 ⟸ ENSRNOT00000106136

RefSeq Acc Id:	NP_001386472 ⟸ NM_001399543
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A0A8I6ACJ4 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386471 ⟸ NM_001399542
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A0A8I6ACJ4 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386469 ⟸ NM_001399540
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A0A8I6ACJ4 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386468 ⟸ NM_001399539
- Peptide Label:	isoform 1 precursor
- UniProtKB:	A0A8I6ASK1 (UniProtKB/TrEMBL), A6HEG7 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386470 ⟸ NM_001399541
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A0A8I6ACJ4 (UniProtKB/TrEMBL), A6HEG8 (UniProtKB/TrEMBL)

Protein Domains

Fe2OG dioxygenase Prolyl 4-hydroxylase alpha subunit

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZGT6-F1-model_v2	AlphaFold	D3ZGT6	1-535	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309673	AgrOrtholog
BioCyc Gene	G2FUF-25120	BioCyc
Ensembl Genes	ENSRNOG00000033663	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000048172.4	UniProtKB/TrEMBL
	ENSRNOP00000070701	ENTREZGENE
	ENSRNOP00000070701.2	UniProtKB/TrEMBL
	ENSRNOP00000089755	ENTREZGENE
	ENSRNOP00000089755.1	UniProtKB/TrEMBL
	ENSRNOP00000097385	ENTREZGENE
	ENSRNOP00000097385.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000042144.5	UniProtKB/TrEMBL
	ENSRNOT00000077185	ENTREZGENE
	ENSRNOT00000077185.2	UniProtKB/TrEMBL
	ENSRNOT00000104075	ENTREZGENE
	ENSRNOT00000104075.1	UniProtKB/TrEMBL
	ENSRNOT00000106136	ENTREZGENE
	ENSRNOT00000106136.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/TrEMBL
	6.10.140.1460	UniProtKB/TrEMBL
	q2cbj1_9rhob like domain	UniProtKB/TrEMBL
InterPro	Oxoglutarate/Fe-dep_oxygenase	UniProtKB/TrEMBL
	P4HA-like	UniProtKB/TrEMBL
	Pro_4_hyd_alph	UniProtKB/TrEMBL
	Pro_4_hyd_alph_FE2OG_OXY	UniProtKB/TrEMBL
	Pro_4_hyd_alph_N	UniProtKB/TrEMBL
	TPR-like_helical	UniProtKB/TrEMBL
	TPR_repeat	UniProtKB/TrEMBL
KEGG Report	rno:360526	UniProtKB/TrEMBL
NCBI Gene	360526	ENTREZGENE
PANTHER	PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2	UniProtKB/TrEMBL
	PTHR10869	UniProtKB/TrEMBL
Pfam	2OG-FeII_Oxy_3	UniProtKB/TrEMBL
	P4Ha_N	UniProtKB/TrEMBL
PhenoGen	P4ha2	PhenoGen
PROSITE	FE2OG_OXY	UniProtKB/TrEMBL
	TPR	UniProtKB/TrEMBL
SMART	P4Hc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48452	UniProtKB/TrEMBL
UniProt	A0A0G2JYL4_RAT	UniProtKB/TrEMBL
	A0A8I6ACJ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ASK1	ENTREZGENE, UniProtKB/TrEMBL
	A6HEG7	ENTREZGENE, UniProtKB/TrEMBL
	A6HEG8	ENTREZGENE, UniProtKB/TrEMBL
	D3ZGT6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-03	P4ha2	prolyl 4-hydroxylase subunit alpha 2	P4ha2	prolyl 4-hydroxylase, alpha polypeptide II	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-04-23	P4ha2	prolyl 4-hydroxylase, alpha polypeptide II	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	P4ha2_predicted	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	P4ha2_predicted	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide (predicted)			Symbol and Name status set to approved	70820	APPROVED

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InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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