Dcun1d1 (defective in cullin neddylation 1 domain containing 1) - Rat Genome Database

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Gene: Dcun1d1 (defective in cullin neddylation 1 domain containing 1) Rattus norvegicus
Analyze
Symbol: Dcun1d1
Name: defective in cullin neddylation 1 domain containing 1
RGD ID: 1309668
Description: Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in positive regulation of protein neddylation; protein neddylation; and regulation of protein ubiquitination. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of ubiquitin ligase complex. Orthologous to human DCUN1D1 (defective in cullin neddylation 1 domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DCN1, defective in cullin neddylation 1, domain containing 1; DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae); DCN1-like protein 1; DCN1-like protein 1-like; LOC100912352; LOC102553014; LOC310324; Tes3; testis derived transcript 3; uncharacterized LOC102553014
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82120,649,445 - 120,700,879 (-)NCBIGRCr8
mRatBN7.22118,721,275 - 118,772,606 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2118,721,822 - 118,772,602 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2125,276,208 - 125,325,510 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02123,388,894 - 123,438,196 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02118,017,644 - 118,066,958 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02122,476,173 - 122,527,153 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2122,476,173 - 122,646,445 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02142,258,373 - 142,274,371 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42122,339,553 - 122,384,815 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12122,287,721 - 122,331,499 (-)NCBI
Celera2113,691,416 - 113,731,907 (-)NCBICelera
Cytogenetic Map2q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (ISO)
ubiquitin ligase complex  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18826954   PMID:22871113   PMID:28581483  


Genomics

Comparative Map Data
Dcun1d1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82120,649,445 - 120,700,879 (-)NCBIGRCr8
mRatBN7.22118,721,275 - 118,772,606 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2118,721,822 - 118,772,602 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2125,276,208 - 125,325,510 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02123,388,894 - 123,438,196 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02118,017,644 - 118,066,958 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02122,476,173 - 122,527,153 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2122,476,173 - 122,646,445 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02142,258,373 - 142,274,371 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42122,339,553 - 122,384,815 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12122,287,721 - 122,331,499 (-)NCBI
Celera2113,691,416 - 113,731,907 (-)NCBICelera
Cytogenetic Map2q25NCBI
DCUN1D1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383182,938,074 - 182,985,918 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3182,938,074 - 182,985,953 (-)EnsemblGRCh38hg38GRCh38
GRCh373182,655,862 - 182,703,706 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363184,143,253 - 184,181,020 (-)NCBINCBI36Build 36hg18NCBI36
Celera3181,095,010 - 181,132,568 (-)NCBICelera
Cytogenetic Map3q26.33NCBI
HuRef3180,065,325 - 180,102,962 (-)NCBIHuRef
CHM1_13182,623,460 - 182,661,204 (-)NCBICHM1_1
T2T-CHM13v2.03185,743,177 - 185,791,010 (-)NCBIT2T-CHM13v2.0
Dcun1d1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39335,946,254 - 35,991,626 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl335,946,254 - 35,991,594 (-)EnsemblGRCm39 Ensembl
GRCm38335,892,105 - 35,937,472 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl335,892,105 - 35,937,445 (-)EnsemblGRCm38mm10GRCm38
MGSCv37335,791,903 - 35,828,996 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36336,084,530 - 36,121,623 (-)NCBIMGSCv36mm8
Celera335,779,336 - 35,817,234 (-)NCBICelera
Cytogenetic Map3BNCBI
cM Map317.41NCBI
Dcun1d1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542011,706,649 - 11,747,471 (-)NCBIChiLan1.0ChiLan1.0
DCUN1D1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22180,808,249 - 180,846,855 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13180,809,040 - 180,851,574 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03179,969,744 - 180,016,270 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13188,140,321 - 188,187,885 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3188,140,321 - 188,187,885 (-)Ensemblpanpan1.1panPan2
DCUN1D1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13415,962,629 - 15,998,910 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3415,966,241 - 15,998,834 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3420,052,025 - 20,087,978 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03415,870,937 - 15,906,915 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3415,870,172 - 15,902,294 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13415,911,618 - 15,947,579 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03415,892,520 - 15,928,519 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03416,135,166 - 16,171,124 (-)NCBIUU_Cfam_GSD_1.0
Dcun1d1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602112,677,292 - 112,724,779 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936566509,863 - 544,884 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936566507,043 - 543,438 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCUN1D1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113120,914,001 - 120,950,825 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213130,336,441 - 130,375,518 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DCUN1D1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1156,428,748 - 6,472,596 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl156,434,086 - 6,469,868 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606315,235,048 - 15,276,957 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcun1d1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473060,682,794 - 60,724,598 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dcun1d1
168 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:86
Count of miRNA genes:72
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000068334
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)259134147127460910Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)276539322150540526Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)278665616143657569Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
61392Bp6Blood pressure QTL 67arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)280270434125270434Rat
1598865Bp296Blood pressure QTL 2962.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)281018907126018907Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1578772Stresp14Stress response QTL 1450.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)282345893130923501Rat
7207808Bmd89Bone mineral density QTL 894.1femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)288862519133862519Rat
2300165Bmd49Bone mineral density QTL 494.80.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)288862519133862519Rat
2300170Bmd45Bone mineral density QTL 4512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)288862519133862519Rat
2300185Bmd46Bone mineral density QTL 468.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)288862519133862519Rat
1598862Glom9Glomerulus QTL 93.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)292337601137337601Rat
1598863Cm65Cardiac mass QTL 652.3heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)292337601137337601Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2102803808147803808Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2104559726149559726Rat
1581552Pur12Proteinuria QTL 125.190.0009urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)2112103657148076632Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1354594Despr10Despair related QTL 100.00000249locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)2114654253159654253Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527143657569Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527143657569Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
5135226Leukc2Leukocyte quantity QTL 2eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)2118111229149559726Rat
1582257Gluco21Glucose level QTL 213.10.0035blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2118111229157142209Rat
738007Anxrr7Anxiety related response QTL 74.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2118189491163189491Rat

Markers in Region
D2Got75  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22118,768,579 - 118,768,724 (+)MAPPERmRatBN7.2
Rnor_6.02122,642,671 - 122,642,815NCBIRnor6.0
Rnor_6.02122,521,733 - 122,521,877NCBIRnor6.0
Rnor_5.02142,275,633 - 142,275,777UniSTSRnor5.0
Rnor_5.02142,157,357 - 142,157,501UniSTSRnor5.0
RGSC_v3.42122,386,076 - 122,386,221RGDRGSC3.4
RGSC_v3.42122,386,077 - 122,386,221UniSTSRGSC3.4
RGSC_v3.12122,331,039 - 122,331,183RGD
Celera2113,733,045 - 113,733,195UniSTS
RH 3.4 Map2677.3UniSTS
RH 3.4 Map2677.3RGD
Cytogenetic Map2q25UniSTS
BF396735  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22118,755,658 - 118,755,843 (+)MAPPERmRatBN7.2
Rnor_6.02122,629,750 - 122,629,934NCBIRnor6.0
Rnor_6.02122,508,813 - 122,508,997NCBIRnor6.0
Rnor_5.02142,262,712 - 142,262,896UniSTSRnor5.0
Rnor_5.02142,144,437 - 142,144,621UniSTSRnor5.0
RGSC_v3.42122,373,156 - 122,373,340UniSTSRGSC3.4
Celera2113,720,248 - 113,720,432UniSTS
RH 3.4 Map2681.5UniSTS
Cytogenetic Map2q25UniSTS
AW532087  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22118,724,204 - 118,724,415 (+)MAPPERmRatBN7.2
Rnor_6.02122,478,658 - 122,478,868NCBIRnor6.0
Rnor_5.02142,114,282 - 142,114,492UniSTSRnor5.0
RGSC_v3.42122,341,934 - 122,342,144UniSTSRGSC3.4
Celera2113,693,793 - 113,694,003UniSTS
RH 3.4 Map2681.5UniSTS
Cytogenetic Map2q25UniSTS
RH130411  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22118,722,390 - 118,722,646 (+)MAPPERmRatBN7.2
mRatBN7.22118,722,433 - 118,722,646 (+)MAPPERmRatBN7.2
Rnor_6.02122,476,887 - 122,477,099NCBIRnor6.0
Rnor_6.02122,476,783 - 122,477,099NCBIRnor6.0
Rnor_5.02142,112,407 - 142,112,723UniSTSRnor5.0
Rnor_5.02142,112,511 - 142,112,723UniSTSRnor5.0
RGSC_v3.42122,340,163 - 122,340,375UniSTSRGSC3.4
Celera2113,692,026 - 113,692,238UniSTS
RH 3.4 Map2681.5UniSTS
Cytogenetic Map2q25UniSTS
RH132791  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22118,772,548 - 118,772,728 (+)MAPPERmRatBN7.2
Rnor_6.02122,646,640 - 122,646,819NCBIRnor6.0
Rnor_6.02122,525,702 - 122,525,881NCBIRnor6.0
Rnor_5.02142,279,602 - 142,279,781UniSTSRnor5.0
Rnor_5.02142,161,326 - 142,161,505UniSTSRnor5.0
RGSC_v3.42122,390,046 - 122,390,225UniSTSRGSC3.4
Celera2113,737,020 - 113,737,199UniSTS
RH 3.4 Map2678.1UniSTS
Cytogenetic Map2q25UniSTS
RH140385  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22118,721,709 - 118,721,899 (+)MAPPERmRatBN7.2
Rnor_6.02122,476,059 - 122,476,248NCBIRnor6.0
Rnor_5.02142,111,683 - 142,111,872UniSTSRnor5.0
RGSC_v3.42122,339,439 - 122,339,628UniSTSRGSC3.4
Celera2113,691,302 - 113,691,491UniSTS
RH 3.4 Map21413.1UniSTS
Cytogenetic Map2q25UniSTS
AI102690  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22118,724,677 - 118,724,887 (+)MAPPERmRatBN7.2
Rnor_6.02122,479,131 - 122,479,340NCBIRnor6.0
Rnor_5.02142,114,755 - 142,114,964UniSTSRnor5.0
RGSC_v3.42122,342,407 - 122,342,616UniSTSRGSC3.4
Celera2113,694,266 - 113,694,475UniSTS
RH 3.4 Map2681.5UniSTS
Cytogenetic Map2q25UniSTS
UniSTS:234659  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22118,763,445 - 118,763,666 (+)MAPPERmRatBN7.2
Rnor_6.02122,637,537 - 122,637,757NCBIRnor6.0
Rnor_6.02122,516,600 - 122,516,820NCBIRnor6.0
Rnor_5.02142,152,224 - 142,152,444UniSTSRnor5.0
Rnor_5.02142,270,499 - 142,270,719UniSTSRnor5.0
RGSC_v3.42122,380,943 - 122,381,163UniSTSRGSC3.4
Celera2113,728,035 - 113,728,255UniSTS
Cytogenetic Map2q25UniSTS
24.MMHAP12FLH3.seq  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22118,753,830 - 118,754,018 (+)MAPPERmRatBN7.2
Rnor_6.02122,627,922 - 122,628,109NCBIRnor6.0
Rnor_6.02122,506,985 - 122,507,172NCBIRnor6.0
Rnor_5.02142,142,609 - 142,142,796UniSTSRnor5.0
Rnor_5.02142,260,884 - 142,261,071UniSTSRnor5.0
RGSC_v3.42122,371,328 - 122,371,515UniSTSRGSC3.4
Celera2113,718,420 - 113,718,607UniSTS
Cytogenetic Map2q25UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 27 36 26 17 26 3 3 74 26 41 11 3
Low 16 21 15 2 15 5 8 9 5
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000068334   ⟹   ENSRNOP00000059805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2118,724,818 - 118,767,377 (-)Ensembl
Rnor_6.0 Ensembl2122,476,173 - 122,641,409 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000080100   ⟹   ENSRNOP00000074566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2118,724,818 - 118,756,273 (-)Ensembl
Rnor_6.0 Ensembl2122,479,285 - 122,646,445 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104731   ⟹   ENSRNOP00000084408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2118,722,992 - 118,757,012 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104963   ⟹   ENSRNOP00000076537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2118,721,822 - 118,767,377 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109045   ⟹   ENSRNOP00000090810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2118,722,992 - 118,772,602 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111905   ⟹   ENSRNOP00000092738
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2118,722,992 - 118,767,823 (-)Ensembl
RefSeq Acc Id: NM_001395100   ⟹   NP_001382029
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82120,649,445 - 120,695,992 (-)NCBI
mRatBN7.22118,721,275 - 118,767,823 (-)NCBI
RefSeq Acc Id: XM_006232261   ⟹   XP_006232323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82120,652,790 - 120,700,879 (-)NCBI
mRatBN7.22118,721,275 - 118,772,552 (-)NCBI
Rnor_6.02122,478,248 - 122,527,153 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006232262   ⟹   XP_006232324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82120,652,790 - 120,695,744 (-)NCBI
mRatBN7.22118,722,379 - 118,767,378 (-)NCBI
Rnor_6.02122,478,248 - 122,520,677 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102240   ⟹   XP_038958168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82120,666,479 - 120,700,879 (-)NCBI
mRatBN7.22118,736,366 - 118,772,555 (-)NCBI
RefSeq Acc Id: XM_063281773   ⟹   XP_063137843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82120,652,790 - 120,686,582 (-)NCBI
RefSeq Acc Id: XM_063281774   ⟹   XP_063137844
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82120,652,790 - 120,700,879 (-)NCBI
RefSeq Acc Id: XP_006232324   ⟸   XM_006232262
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y621 (UniProtKB/TrEMBL),   A0A0G2K8D6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232323   ⟸   XM_006232261
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ADB9 (UniProtKB/TrEMBL),   A0A8I5ZYZ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074566   ⟸   ENSRNOT00000080100
RefSeq Acc Id: ENSRNOP00000059805   ⟸   ENSRNOT00000068334
RefSeq Acc Id: XP_038958168   ⟸   XM_039102240
- Peptide Label: isoform X4
- UniProtKB: A6IHV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000084408   ⟸   ENSRNOT00000104731
RefSeq Acc Id: ENSRNOP00000092738   ⟸   ENSRNOT00000111905
RefSeq Acc Id: ENSRNOP00000090810   ⟸   ENSRNOT00000109045
RefSeq Acc Id: ENSRNOP00000076537   ⟸   ENSRNOT00000104963
RefSeq Acc Id: NP_001382029   ⟸   NM_001395100
- UniProtKB: A0A8I6AI94 (UniProtKB/TrEMBL),   A0A0G2K8D6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137844   ⟸   XM_063281774
- Peptide Label: isoform X3
- UniProtKB: D3ZRV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063137843   ⟸   XM_063281773
- Peptide Label: isoform X3
- UniProtKB: D3ZRV0 (UniProtKB/TrEMBL)
Protein Domains
DCUN1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K8D6-F1-model_v2 AlphaFold A0A0G2K8D6 1-273 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309668 AgrOrtholog
BioCyc Gene G2FUF-53330 BioCyc
BioCyc Pathway PWY-7899 [protein NEDDylation] BioCyc
BioCyc Pathway Image PWY-7899 BioCyc
Ensembl Genes ENSRNOG00000012734 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068334.3 UniProtKB/TrEMBL
  ENSRNOT00000080100.2 UniProtKB/TrEMBL
  ENSRNOT00000104731.1 UniProtKB/TrEMBL
  ENSRNOT00000104963.1 UniProtKB/TrEMBL
  ENSRNOT00000109045.1 UniProtKB/TrEMBL
  ENSRNOT00000111905 ENTREZGENE
  ENSRNOT00000111905.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.238.200 UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro DCN-prot UniProtKB/TrEMBL
  DCN1-like_PONY UniProtKB/TrEMBL
  DUF298 UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
KEGG Report rno:310324 UniProtKB/TrEMBL
NCBI Gene 310324 ENTREZGENE
PANTHER DCN1-LIKE PROTEIN 1 UniProtKB/TrEMBL
  DUF298 UniProtKB/TrEMBL
Pfam DUF298 UniProtKB/TrEMBL
  UBA_4 UniProtKB/TrEMBL
PhenoGen Dcun1d1 PhenoGen
PROSITE DCUN1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012734 RatGTEx
Superfamily-SCOP UBA_like UniProtKB/TrEMBL
UniProt A0A0G2K8D6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y621 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYZ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ADB9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AI94 ENTREZGENE, UniProtKB/TrEMBL
  A6IHV8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZRV0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Dcun1d1  defective in cullin neddylation 1 domain containing 1  LOC102553014  uncharacterized LOC102553014  Data merged from RGD:7547553 737654 PROVISIONAL
2016-01-20 Dcun1d1  defective in cullin neddylation 1 domain containing 1  Dcun1d1  DCN1, defective in cullin neddylation 1, domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 Dcun1d1  DCN1, defective in cullin neddylation 1, domain containing 1  LOC100912352  DCN1-like protein 1-like  Data merged from RGD:6487193 737654 PROVISIONAL
2013-12-17 LOC102553014  uncharacterized LOC102553014      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-08-01 Dcun1d1  DCN1, defective in cullin neddylation 1, domain containing 1  Dcun1d1  DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100912352  DCN1-like protein 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-06-27     Dcun1d1  Dcn1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-25 Dcun1d1  Dcn1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)  Dcun1d1_predicted  DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dcun1d1_predicted  DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) (predicted)  Tes3_predicted  testis derived transcript 3 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Tes3_predicted  testis derived transcript 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED