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Gene: Abca4 (ATP binding cassette subfamily A member 4) Rattus norvegicus
Symbol: Abca4
Name: ATP binding cassette subfamily A member 4
Description: Predicted to have ATPase-coupled transmembrane transporter activity; N-retinylidene-phosphatidylethanolamine flippase activity; and phosphatidylethanolamine flippase activity. Predicted to be involved in phospholipid transport; photoreceptor cell maintenance; and visual perception. Predicted to localize to endoplasmic reticulum and photoreceptor outer segment. Human ortholog(s) of this gene implicated in fundus dystrophy and retinal degeneration (multiple). Orthologous to human ABCA4 (ATP binding cassette subfamily A member 4); PARTICIPATES IN altered retinoid cycle metabolic pathway; retinitis pigmentosa pathway; retinoid cycle metabolic pathway; INTERACTS WITH bisphenol A; cobalt dichloride; cocaine.
Type: protein-coding
Also known as: ABCR; ATP-binding cassette, sub-family A (ABC1), member 4; ATP-binding cassette, subfamily A (ABC1), member 4; LOC310836; retinal-specific ATP-binding cassette transporter
Homo sapiens (human) : ABCA4 (ATP binding cassette subfamily A member 4)  HGNC  Alliance
Mus musculus (house mouse) : Abca4 (ATP-binding cassette, sub-family A (ABC1), member 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abca4 (ATP binding cassette subfamily A member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCA4 (ATP binding cassette subfamily A member 4)
Canis lupus familiaris (dog) : ABCA4 (ATP binding cassette subfamily A member 4)
Sus scrofa (pig) : ABCA4 (ATP binding cassette subfamily A member 4)
Chlorocebus sabaeus (African green monkey) : ABCA4 (ATP binding cassette subfamily A member 4)
Heterocephalus glaber (naked mole-rat) : Abca4 (ATP binding cassette subfamily A member 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02225,645,539 - 225,783,288 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2225,645,568 - 225,783,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02243,682,218 - 243,818,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42218,712,663 - 218,849,896 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12218,675,724 - 218,812,957 (+)NCBI
Celera2202,594,748 - 202,731,906 (+)NCBICelera
Cytogenetic Map2q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Abca4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309445
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.