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Gene: Nek1 (NIMA-related kinase 1) Rattus norvegicus
Symbol: Nek1
Name: NIMA-related kinase 1
Description: Predicted to have 14-3-3 protein binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including DNA damage response, detection of DNA damage; regulation of DNA damage checkpoint; and response to ionizing radiation. Predicted to localize to centrosome; cytosol; and nucleoplasm. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; asphyxiating thoracic dystrophy; and short-rib thoracic dysplasia 6 with or without polydactyly. Orthologous to human NEK1 (NIMA related kinase 1); INTERACTS WITH bisphenol A; chloroprene; oxaliplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC290705; NIMA (never in mitosis gene a)-related expressed kinase 1; NIMA (never in mitosis gene a)-related kinase 1; serine/threonine-protein kinase Nek1
Homo sapiens (human) : NEK1 (NIMA related kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Nek1 (NIMA (never in mitosis gene a)-related expressed kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nek1 (NIMA related kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NEK1 (NIMA related kinase 1)
Canis lupus familiaris (dog) : NEK1 (NIMA related kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nek1 (NIMA related kinase 1)
Sus scrofa (pig) : NEK1 (NIMA related kinase 1)
Chlorocebus sabaeus (African green monkey) : NEK1 (NIMA related kinase 1)
Heterocephalus glaber (naked mole-rat) : Nek1 (NIMA related kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01632,321,010 - 32,439,421 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1632,321,010 - 32,439,421 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01631,025,718 - 31,032,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01632,155,914 - 32,274,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41632,317,987 - 32,438,010 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11632,320,904 - 32,431,386 (-)NCBI
Celera1628,993,115 - 29,112,552 (-)NCBICelera
Cytogenetic Map16p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nek1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309375
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.